aconiazide and Weight-Loss

aconiazide has been researched along with Weight-Loss* in 1 studies

Other Studies

1 other study(ies) available for aconiazide and Weight-Loss

Article	Year
Upper confidence limits on excess risk for quantitative responses. Risk analysis : an official publication of the Society for Risk Analysis, 1993, Volume: 13, Issue:2 The definition and observation of clear-cut adverse health effects for continuous (quantitative) responses, such as altered body weights or organ weights, are difficult propositions. Thus, methods of risk assessment commonly used for binary (quantal) toxic responses such as cancer are not directly applicable. In this paper, two methods for calculating upper confidence limits on excess risk for quantitative toxic effects are proposed, based on a particular definition of an adverse quantitative response. The methods are illustrated with data from a dose-response study, and their performance is evaluated with a Monte Carlo simulation study. Topics: Animals; Dose-Response Relationship, Drug; Female; Hazardous Substances; Humans; Isoniazid; Models, Statistical; Monte Carlo Method; Probability; Rats; Rats, Inbred F344; Risk Factors; Weight Loss	1993

Article

Year

Upper confidence limits on excess risk for quantitative responses.

Risk analysis : an official publication of the Society for Risk Analysis, 1993, Volume: 13, Issue:2

The definition and observation of clear-cut adverse health effects for continuous (quantitative) responses, such as altered body weights or organ weights, are difficult propositions. Thus, methods of risk assessment commonly used for binary (quantal) toxic responses such as cancer are not directly applicable. In this paper, two methods for calculating upper confidence limits on excess risk for quantitative toxic effects are proposed, based on a particular definition of an adverse quantitative response. The methods are illustrated with data from a dose-response study, and their performance is evaluated with a Monte Carlo simulation study.

Topics: Animals; Dose-Response Relationship, Drug; Female; Hazardous Substances; Humans; Isoniazid; Models, Statistical; Monte Carlo Method; Probability; Rats; Rats, Inbred F344; Risk Factors; Weight Loss

1993