aclarubicin and Gallbladder-Neoplasms

Cancer of the gallbladder is radioresistant. When a case of such was found inoperable, she was subjected to radiotherapy combined with aclarubicin and neocarzinostatin. Therapeutic effectiveness was confirmed at autopsy as she later succumbed to uterine cervical cancer. Thus, the present radiochemotherapeutic regimen would probably provide a means of overcoming those radioresistant inoperable malignancies. Intravenous administrations of appropriate antibiotics such as azthreonam and reniran may probably be helpful in the prevent ion and treatment of septic peritonitis possible during the course of reinforced radiotherapy of the abdomen.

Topics: Aclarubicin; Anti-Bacterial Agents; Combined Modality Therapy; Drug Therapy, Combination; Female; Gallbladder Neoplasms; Humans; Middle Aged; Radiotherapy Dosage; Zinostatin

Cancer of the gallbladder is radioresistant. When a 59-year-old woman was found to have an inoperable cancer of the gallbladder, she was subjected to radiotherapy combined with aclarubicin and neocarzinostatin. Therapeutic effectiveness was confirmed at autopsy as she later succumbed to uterine cervical cancer. Thus, the present radiochemotherapeutic regimen would probably provide a means of overcoming those radioresistant inoperable malignancies.

Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; DNA Damage; Female; Gallbladder Neoplasms; Humans; Middle Aged; Zinostatin