acivicin has been researched along with Neoplasms in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (50.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arellano, ML; Boggon, TJ; Brat, DJ; Chen, GZ; Chen, J; Chen, PR; DeBerardinis, RJ; Elf, S; Fan, J; Gu, TL; He, C; Hitosugi, T; Hurwitz, SJ; Ji, Q; Jiang, L; Kang, HB; Kang, S; Khoury, HJ; Khuri, FR; Lee, BH; Lei, Q; Li, Y; Lin, R; Lonial, S; Mao, H; Mitsche, M; Seo, JH; Shan, C; Sudderth, J; Tucker, M; Wang, D; Wu, S; Xie, J; Ye, K; Zhang, L; Zhang, S; Zhou, L | 1 |
| Brumby, AM; Humbert, PO; Manning, SA; Parisot, JP; Richardson, HE; Schlosser, T; Street, IP; Willoughby, LF | 1 |
| Weber, G | 1 |
| Alonso, MT; Leyland-Jones, B; O'Dwyer, PJ | 1 |
| Belt, RJ; Haas, CD; Hoogstraten, B; Joseph, U; Taylor, S | 1 |
| Bruno, S; McGovren, JP; Neil, GL; Penta, J; Poster, DS | 1 |
| Kufe, DW; McGovren, JP; Schade, D; Weiss, GR | 1 |
| Souba, WW | 1 |
| Baruchel, S; Bell, B; Bernstein, M; Devine, S; Dubowy, R; Grier, H; Kretschmar, C; Langevin, AM; Vietti, T; Whitehead, VM | 1 |
| Brown, T; Hidalgo, M; Kuhn, JG; MacGovren, JP; Rodriguez, G; Rowinsky, EK; Von Hoff, DD; Weiss, G | 1 |
| Doi, H; Komatsu, H; Nishihira, T; Satomi, S | 1 |
| Alberti, D; Bruggink, J; Earhart, RH; Fischer, PH; Hamilton, RD; Koeller, JM; Simon, K; Tormey, DC; Tutsch, K; Willson, JK | 1 |
5 review(s) available for acivicin and Neoplasms
| Article | Year |
|---|---|
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; Oxidative Stress; Pentose Phosphate Pathway; Phosphogluconate Dehydrogenase; Protein Serine-Threonine Kinases; Ribulosephosphates; Signal Transduction | 2015 |
Biochemical strategy of cancer cells and the design of chemotherapy: G. H. A. Clowes Memorial Lecture.
Topics: Adenosine Monophosphate; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Deoxyribonucleotides; Gene Expression Regulation; Gluconeogenesis; Guanosine Monophosphate; Humans; Inosine Monophosphate; Isoxazoles; Kidney Neoplasms; Liver Neoplasms; Liver Regeneration; Models, Biological; Neoplasms; Purines; Pyrimidines; Ribonucleotides | 1983 |
Acivicin. An antitumor antibiotic.
Topics: Animals; Antibiotics, Antineoplastic; Glycine; Humans; Isoxazoles; Neoplasms; Neoplasms, Experimental; Oxazoles | 1981 |
Glutamine and cancer.
Topics: Antimetabolites, Antineoplastic; Cell Division; Diazooxonorleucine; Glutamine; Humans; Intestinal Mucosa; Intestines; Isoxazoles; Lymphocytes; Muscles; Neoplasms; Parenteral Nutrition, Total; Randomized Controlled Trials as Topic | 1993 |
[Anti-cancer therapy with amino acid imbalance].
Topics: Amino Acids; Antimetabolites, Antineoplastic; Arginine; Asparagine; Glutamine; Humans; Isoxazoles; Methionine; Neoplasms; Valine | 2001 |
2 trial(s) available for acivicin and Neoplasms
| Article | Year |
|---|---|
A phase I study of acivicin in refractory pediatric solid tumors. A Pediatric Oncology Group study.
Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Drug Resistance, Neoplasm; Enzyme Inhibitors; gamma-Glutamyltransferase; Humans; Injections, Intravenous; Isoxazoles; Neoplasms; Tumor Cells, Cultured | 1995 |
A Phase I and pharmacological study of the glutamine antagonist acivicin with the amino acid solution aminosyn in patients with advanced solid malignancies.
Topics: Adult; Aged; Amino Acids; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Electrolytes; Female; Glucose; Glutamine; Humans; Isoxazoles; Male; Middle Aged; Neoplasms; Parenteral Nutrition Solutions; Solutions; Thrombocytopenia; Treatment Outcome | 1998 |
5 other study(ies) available for acivicin and Neoplasms
| Article | Year |
|---|---|
An in vivo large-scale chemical screening platform using Drosophila for anti-cancer drug discovery.
Topics: Animals; Antineoplastic Agents; Benzamides; Biological Availability; Cell Proliferation; Cytidine Triphosphate; Diphenylamine; Drosophila melanogaster; Drug Screening Assays, Antitumor; Glutamine; Isoxazoles; Neoplasms; Pharmacogenetics; Pilot Projects | 2013 |
Acivicin: a new glutamine antagonist in clinical trials.
Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites; Dose-Response Relationship, Drug; Drug Evaluation; Female; Glutamine; Half-Life; Humans; Isoxazoles; Kinetics; Leukemia, Experimental; Liver Neoplasms, Experimental; Macaca mulatta; Male; Mice; Neoplasms; Oxazoles; Purines; Pyrimidines; Sarcoma, Experimental | 1984 |
Phase I evaluation of AT-125 single dose every three weeks.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Central Nervous System; Drug Administration Schedule; Drug Evaluation; Glutamine; Humans; Isoxazoles; Middle Aged; Neoplasms; Oxazoles | 1984 |
Phase I and pharmacological study of acivicin by 24-hour continuous infusion.
Topics: Antimetabolites; Digestive System; Drug Evaluation; Humans; Infusions, Parenteral; Isoxazoles; Kinetics; Neoplasms; Nervous System; Oxazoles | 1982 |
Phase I clinical trial of a combination of dipyridamole and acivicin based upon inhibition of nucleoside salvage.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chromatography, High Pressure Liquid; Dipyridamole; Drug Evaluation; Humans; Isoxazoles; Leukocyte Count; Metabolic Clearance Rate; Neoplasms; Nucleosides | 1988 |