Page last updated: 2024-08-23

acitretin and Alzheimer Disease

acitretin has been researched along with Alzheimer Disease in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's3 (30.00)24.3611
2020's6 (60.00)2.80

Authors

AuthorsStudies
Abu Nasra, NO; Dawood, KM; Elzayat, EM; Hagag, NM; Hosney, M; Yehya, MM1
El-Sherif, AA; Elzayat, EM; Hosney, M; Shahien, SA2
Ge, S; Guyatt, G; Lu, L; Tang, C; Wang, S; Wen, H; Xu, M; Xu, N; Yao, G; Zeng, J; Zhang, Y; Zheng, X1
Barger, Z; Dos Santos Guilherme, M; Endres, K; Reinhardt, S; Roesler, MK; Rosales Jubal, E; Ruffini, N; Schmeisser, MJ; Schmitt, U; Schuck, F; Schwalm, M; Stroh, A; Tose, A; Wierczeiko, A1
Bachmann, CM; Boehm, U; Dos Santos Guilherme, M; Endres, K; Grimm, HS; Grimm, MOW; Hartmann, T; Janitschke, D; Lauer, AA; Nguyen, VTT; Qiao, S; Schrul, B1
Brummer, T; Endres, K; Fellgiebel, A; Lichtenthaler, SF; Müller, SA; Pan-Montojo, F; Tomita, T; Yoshida, F1
Endres, K; Freese, C; Hefner, G; Kirkpatrick, CJ; Reinhardt, S; Unger, RE1
Endres, K; Fahrenholz, F; Fellgiebel, A; Hiemke, C; Lieb, K; Lotz, J; Teipel, S; Tüscher, O1
Endres, K; Fahrenholz, F; Hundt, J; Schneider, A; Tippmann, F1

Reviews

2 review(s) available for acitretin and Alzheimer Disease

ArticleYear
miRNAs and Stem Cells as Promising Diagnostic and Therapeutic Targets for Alzheimer's Disease.
    Journal of Alzheimer's disease : JAD, 2023, Volume: 94, Issue:s1

    Topics: Acitretin; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Disease Susceptibility; Humans; MicroRNAs; Stem Cell Transplantation; Stem Cells

2023
Anti-Aβ agents for mild to moderate Alzheimer's disease: systematic review and meta-analysis.
    Journal of neurology, neurosurgery, and psychiatry, 2020, Volume: 91, Issue:12

    Topics: Acitretin; Alanine; Alzheimer Disease; Amyloid beta-Peptides; Antibodies, Monoclonal, Humanized; Anxiety; Azepines; Clioquinol; Copper; Cyclic S-Oxides; Depression; Diarrhea; Exanthema; Fatigue; Flurbiprofen; Humans; Immunoglobulins, Intravenous; Inositol; Mental Status and Dementia Tests; Minimal Clinically Important Difference; Orotic Acid; Oxadiazoles; Severity of Illness Index; Sulfonamides; Syncope; Thiadiazines; Treatment Outcome; Vomiting

2020

Trials

1 trial(s) available for acitretin and Alzheimer Disease

ArticleYear
Increased CSF APPs-α levels in patients with Alzheimer disease treated with acitretin.
    Neurology, 2014, Nov-18, Volume: 83, Issue:21

    Topics: Acitretin; Aged; Alzheimer Disease; Amyloid Precursor Protein Secretases; Biomarkers; Double-Blind Method; Female; Humans; Male; Middle Aged; Pilot Projects; Prospective Studies; Treatment Outcome

2014

Other Studies

7 other study(ies) available for acitretin and Alzheimer Disease

ArticleYear
Regulatory Effect of Adipose-Derived Mesenchymal Stem Cells and/ or Acitretin on Adam10 Gene in Alzheimer's Disease Rat Model.
    Current stem cell research & therapy, 2022, Volume: 17, Issue:4

    Topics: Acitretin; ADAM10 Protein; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Male; Mesenchymal Stem Cells; Neurodegenerative Diseases; Rats

2022
Therapeutic potential of stem cells and acitretin on inflammatory signaling pathway-associated genes regulated by miRNAs 146a and 155 in AD-like rats.
    Scientific reports, 2023, 06-13, Volume: 13, Issue:1

    Topics: Acitretin; Alzheimer Disease; Animals; Male; MicroRNAs; NF-kappa B; Rats; Signal Transduction; Stem Cells

2023
Acitretin reverses early functional network degradation in a mouse model of familial Alzheimer's disease.
    Scientific reports, 2021, 03-23, Volume: 11, Issue:1

    Topics: Acitretin; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Brain Waves; Calcium; Disease Models, Animal; Humans; Immunohistochemistry; Mice; Neural Pathways; Neurons; Optical Imaging; Plaque, Amyloid; Protein Aggregation, Pathological; Synapses

2021
Shotgun lipidomics of liver and brain tissue of Alzheimer's disease model mice treated with acitretin.
    Scientific reports, 2021, 07-27, Volume: 11, Issue:1

    Topics: Acitretin; Alzheimer Disease; Animals; Brain; Disease Models, Animal; Lipidomics; Liver; Mice; Models, Biological

2021
NrCAM is a marker for substrate-selective activation of ADAM10 in Alzheimer's disease.
    EMBO molecular medicine, 2019, Volume: 11, Issue:4

    Topics: Acitretin; ADAM10 Protein; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cell Adhesion Molecules; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Neuronal Outgrowth; Neurons; Proteolysis; Proteome; Rats; RNA Interference; RNA, Small Interfering; Substrate Specificity; Tetraspanins

2019
A novel blood-brain barrier co-culture system for drug targeting of Alzheimer's disease: establishment by using acitretin as a model drug.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Acitretin; ADAM Proteins; ADAM10 Protein; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Biological Assay; Biological Transport; Blood-Brain Barrier; Brain; Cell Line, Tumor; Coculture Techniques; Drug Delivery Systems; Endothelial Cells; Endothelium, Vascular; Gene Expression; Genes, Reporter; Humans; Keratolytic Agents; Luciferases; Membrane Proteins; Models, Biological; Neurons; Promoter Regions, Genetic; Recombinant Fusion Proteins; Swine

2014
Up-regulation of the alpha-secretase ADAM10 by retinoic acid receptors and acitretin.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2009, Volume: 23, Issue:6

    Topics: Acitretin; ADAM Proteins; ADAM10 Protein; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Cell Line; DNA-Binding Proteins; Gene Expression Regulation; Humans; Keratolytic Agents; Liver X Receptors; Male; Membrane Proteins; Mice; Mice, Transgenic; Molecular Structure; Orphan Nuclear Receptors; PPAR gamma; Promoter Regions, Genetic; Receptors, Calcitriol; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Thyroid Hormone; Retinoid X Receptors; Tretinoin; Up-Regulation

2009