acid-phosphatase and Schistosomiasis-haematobia

Urinary alkaline phosphatase (ALP), acid phosphatase (ACP), aryl sulphatase (Ar. sulph.), beta-glucuronidase (beta-gluc.) and galactosidase were assayed in a group of Bilharzia haematobium patients and another group of healthy subjects (control group). The results for most of the determined enzymes revealed high activities as compared to the controls. The activity of acid phosphatase in male urine samples increased also, though not significantly. These elevated enzyme activities could be used to establish the diagnosis of schistosomiasis in patients whose urine contains no ova or when it is difficult to detect them. The results are discussed in the light of localization of each enzyme in the urinary tract as well as in other organs like the liver.

Topics: Acid Phosphatase; Adult; Alkaline Phosphatase; Biomarkers; Child; Female; Galactosidases; Glucuronidase; Humans; Male; Schistosomiasis haematobia; Sulfatases

Topics: Acid Phosphatase; Adolescent; Alkaline Phosphatase; Child; Child, Preschool; Humans; Muramidase; Nigeria; Schistosomiasis haematobia; Serum Albumin; Serum Globulins

Variation in serum prostatic acid phosphatase (PAP) level over a twenty-four-hour period was studied in 18 urologic patients with no prostatic disease. Hourly, twenty-four-hour serum PAP level was determined using Elisa method. Seven of 18 patients (38.8%) showed appreciable change with definite diurnal pattern. PAP level was highest in early AM hours and lowest in the PM period. The difference between the mean AM and PM periods was statistically significant (P less than 0.01). Four of 18 patients showed no change over the twenty-four hours while 7 patients showed some variation without definite diurnal pattern. Such changes may lead to variation in serum PAP level and may lead to false positive results.

Topics: Acid Phosphatase; Adult; Aged; Circadian Rhythm; Clinical Enzyme Tests; Cystitis; Enzyme-Linked Immunosorbent Assay; Humans; Male; Middle Aged; Prostate; Schistosomiasis haematobia; Urethral Stricture; Urinary Calculi; Urologic Diseases

Topics: Acid Phosphatase; Adult; Female; Humans; Male; Middle Aged; Neoplasms; Nigeria; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Radioimmunoassay; Schistosomiasis haematobia