acid-phosphatase and Pre-Eclampsia

Topics: Acid Phosphatase; Adult; Erythroblastosis, Fetal; Female; Humans; Leukocyte Count; Lymphocytes; Neutrophils; Pre-Eclampsia; Pregnancy; Rh-Hr Blood-Group System

Among 30 pregnant women with EPH-gestosis activity of myeloperoxidase was significantly decreased and activity of acid phosphatase was not much increased. Results of scientific researches can confirm the fact of weakness of anti-infection immunity among women with EPH-gestosis in compare with healthy pregnant women.

Topics: Acid Phosphatase; Adult; Female; Granulocytes; Humans; Peroxidase; Pre-Eclampsia; Pregnancy

Topics: Acid Phosphatase; Adolescent; Adult; Alkaline Phosphatase; Female; Humans; Lipids; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Third

Topics: Acid Phosphatase; Adult; Female; Humans; Leukocyte Count; Leukocytosis; Lymphocytes; Neutrophils; Pre-Eclampsia; Pregnancy

171 samples of amniotic fluid were obtained by abdominal amniocentesis from 67 women with complicated pregnancies (isoimmunization, diabetes mellitus or toxaemia). The levels of heat-labile alkaline phosphatase (HLAP), heat-stable alkaline phosphatase (HSAP) and acid phosphatase (AcP) were determined and compared to the enzyme levels in 179 samples from women with normal pregnancies of corresponding gestational ages. HLAP showed two "peaks" of activity, one in the 5th-22nd week and the other at term. HSAP and AcP showed increased activity at term. HSAP was decreased (p less than 0.01) in isoimmunization between the 36th and 40th week. 11 cases of toxaemia with placental insufficiency showed no differences in the levels of HLAP and HSAP compared with normal pregnancy. AcP showed no differences between normal and complicated pregnancy. Samples contaminated by blood showed no significant increase in the acid- and alkaline phosphatase levels. Samples contaminated by meconium showed a complex pattern. Some samples had normal enzyme levels, some had high levels of HLAP only and some had high levels of HSAP and AcP. The origin of the enzymes is not known with certainty. HSAP in amniotic fluid is most likely not of placental but intestinal origin. Determinations of acid- and alkaline phosphatase in amniotic fluid seem to be of little values in the clinical management of complicated pregnancy.

Topics: Acid Phosphatase; Alkaline Phosphatase; Amniotic Fluid; Blood Group Incompatibility; Female; Humans; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pregnancy Complications, Hematologic; Pregnancy in Diabetics

The subcellular localisation of acid and alkaline phosphatase has been studied in the trophoblast of placentae from both normal and complicated pregnancies. In placentae from uncomplicated pregnancies the number of trophoblastic acid-phosphatase-containing organelles decreases progressively as gestation proceeds whilst alkaline-phosphatase activity, although abundant at term, could not be demonstrated during the early stages of pregnancy. The acid-phosphatase-containing organelles are of two types; one is a small round body which is probably a lysosome whilst the other is a multivesicular body. The alkaline phosphatase is distributed mainly on the syncytial microvilli and plasma-membrane. It is suggested that the marked lysosomal activity during early pregnancy is related to the architectural refashioning of the placenta during this period and that there are two phosphatase-linked transfer systems in the trophoblast, one dependent upon acid-phosphatase-containing multivesicular bodies and being utilised during early pregnancy and the other reliant upon alkaline phosphatase and dominating during the second half of gestation. In placentae from prolonged pregnancies there is a further decrease in trophoblastic acid phosphatase and, usually, a continuing increase in alkaline-phosphatase activity. In placentae from babies of low birth weight this trend is sometimes reversed and alkaline-phosphatase activity either disappears or its reaction product diffuses throughout the syncytium; this is usually accompanied by a marked increase in the number of acid-phosphatase-containing multivesicular bodies. Placentae from women with pre-eclampsia show no loss of alkaline-phosphatase activity but are characterised by an increased number of lysosomal bodies.

Topics: Acid Phosphatase; Alkaline Phosphatase; Birth Weight; Female; Histocytochemistry; Humans; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pregnancy, Prolonged; Trophoblasts

Topics: Acid Phosphatase; Adolescent; Adult; Alkaline Phosphatase; Female; Humans; Infant, Newborn; Pre-Eclampsia; Pregnancy; Umbilical Cord

Topics: Acid Phosphatase; Alkaline Phosphatase; Decidua; Female; Galactosidases; Gestational Age; Glucosephosphate Dehydrogenase; Glucuronidase; Humans; Hydroxysteroid Dehydrogenases; Isocitrate Dehydrogenase; L-Lactate Dehydrogenase; Leucyl Aminopeptidase; Monoamine Oxidase; Placenta Diseases; Pre-Eclampsia; Pregnancy; Sulfatases; Trophoblasts

Topics: Acid Phosphatase; Alkaline Phosphatase; Cytochrome Reductases; Esterases; Female; Gestational Age; Glucosephosphate Dehydrogenase; Humans; Isocitrate Dehydrogenase; L-Lactate Dehydrogenase; Monoamine Oxidase; Placenta Diseases; Pre-Eclampsia; Pregnancy; Succinate Dehydrogenase

Topics: Acid Phosphatase; Alkaline Phosphatase; Female; Histocytochemistry; Humans; Oxidoreductases; Placenta; Pre-Eclampsia; Pregnancy

Topics: Acid Phosphatase; Alkaline Phosphatase; Blood Group Incompatibility; Female; Humans; Infant, Newborn; Myocardial Infarction; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pregnancy Complications, Cardiovascular; Pregnancy, Prolonged; Rh-Hr Blood-Group System

Topics: Acid Phosphatase; Cathepsins; Female; Humans; Placenta; Pre-Eclampsia; Pregnancy

Topics: Acid Phosphatase; Blood Platelets; Blood Proteins; Female; Humans; Kidney; Placenta; Postpartum Period; Pre-Eclampsia; Pregnancy

Topics: Acid Phosphatase; Alkaline Phosphatase; Female; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Glycerolphosphate Dehydrogenase; Histocytochemistry; Humans; Hypertension; L-Lactate Dehydrogenase; Leucyl Aminopeptidase; Malate Dehydrogenase; Oxidoreductases; Placenta; Pre-Eclampsia; Pregnancy; Succinate Dehydrogenase

Topics: Acid Phosphatase; Amniotic Fluid; Female; Humans; Pre-Eclampsia; Pregnancy; Toxemia