acid-phosphatase and Orbital-Neoplasms

A patient with known prostatic cancer presented with bilateral orbital masses. On CT there was a bulky soft-tissue mass in the cranial aspect of each orbit. An open biopsy revealed undifferentiated tissue that stained strongly positive for prostatic-specific acid phosphatase, confirming the diagnosis of metastatic prostate carcinoma.

Topics: Acid Phosphatase; Adenocarcinoma; Humans; Male; Middle Aged; Orbital Neoplasms; Prostatic Neoplasms; Tomography, X-Ray Computed

A 66-year-old man presented with progressive proptosis of the left eye associated with ocular pain. A computed tomographic scan showed a high density mass in the posterolateral portion of the left orbit. The patient underwent surgical removal of the tumor and histopathological examination revealed adenocarcinoma of unknown origin. To find out the primary focus of the tumor the patient was referred to our department, where biopsy of the prostate revealed adenocarcinoma. Further, immunohistochemical examination of the orbital tumor was performed and prostatic acid phosphatase was identified. Finally, we made a diagnosis of orbital metastasis from prostatic carcinoma. This paper presents a rare case of prostatic carcinoma with orbital metastasis and reviews the literature of the subject.

Topics: Acid Phosphatase; Adenocarcinoma; Aged; Humans; Immunohistochemistry; Male; Orbital Neoplasms; Prostate; Prostatic Neoplasms

Topics: Acid Phosphatase; Adenocarcinoma; Aged; Humans; Male; Neoplasm Metastasis; Orbital Neoplasms; Prostatic Neoplasms

Topics: Acid Phosphatase; Adenosine Triphosphatases; Alkaline Phosphatase; Animals; Cattle; Cattle Diseases; Citric Acid Cycle; Esterases; Fibroma; Histocytochemistry; Lipase; Orbit; Orbital Neoplasms; Papilloma; Succinate Dehydrogenase