acid-phosphatase and Oligodendroglioma

The tartrat resistant zinc activated acid phosphatase (ZT-AP) was investigated in 17 glial microtumours of the rat brain. The tumours were induced by N-ethyl-N-nitrosourea injected to newborn rats subcutaneously (85 mg/kg body weight). The morphology of these microtumours corresponds to the statements in the literature. In regard to their behaviour of the investigated enzyme the microtumours may be divided in 2 groups: 1) Microtumours with an activity of acid phosphatases but without any histochemically demonstrable activity of ZT-AP. Histologically they correspond to oligodendric microgliomas. 2) Microtumours with a high activity of acid phosphatases and a remarkable activity of ZT-AP especially in the perivascular cell proliferations. This type corresponds histologically to the astrocytic and mixed glial proliferations including glioblastomas. According to our present findings the ZT-AP was found in astrocytes and especially in mesenchymal cells. In some cases a focal increased activity of ZT-AP could also be observed before histological alterations appeared. We regard it as an early stage of the development of tumours.

Topics: Acid Phosphatase; Animals; Astrocytoma; Brain Neoplasms; Ethylnitrosourea; Female; Histocytochemistry; Male; Oligodendroglioma; Rats; Rats, Inbred Strains; Stimulation, Chemical; Tartrates; Zinc

Topics: Acid Phosphatase; Animals; Astrocytoma; Brain Neoplasms; Female; Glioma; Golgi Apparatus; Lysosomes; Macrophages; Maternal-Fetal Exchange; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Oligodendroglioma; Pregnancy; Rats; Rats, Inbred Strains

Topics: Acid Phosphatase; Animals; Brain; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Glucuronidase; Hexosaminidases; Lysosomes; Male; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Oligodendroglioma; Pregnancy; Rats; Sulfatases

Topics: Acid Phosphatase; Adenosine Triphosphatases; Animals; Animals, Newborn; Brain Neoplasms; Demyelinating Diseases; Encephalomyelitis, Autoimmune, Experimental; Esterases; Fetus; Guinea Pigs; Humans; Mice; Multiple Sclerosis; Myelin Sheath; Neuroglia; Oligodendroglioma; Phosphoric Monoester Hydrolases; Rabbits

Topics: Acid Phosphatase; Adolescent; Adult; Aged; Alcohol Oxidoreductases; Alkaline Phosphatase; Astrocytoma; Brain Neoplasms; Female; Glioma; Glutamate Dehydrogenase; Glycerolphosphate Dehydrogenase; Histocytochemistry; Humans; L-Lactate Dehydrogenase; Male; Middle Aged; Oligodendroglioma; Succinate Dehydrogenase

Topics: Acid Phosphatase; Adenoma, Chromophobe; Astrocytoma; Biopsy; Brain Neoplasms; Choroid Plexus; Ependymoma; Glioblastoma; Hemangiosarcoma; Histocytochemistry; Humans; Medulloblastoma; Meningioma; Neurilemmoma; Oligodendroglioma; Papilloma; Pituitary Neoplasms; Rosaniline Dyes; Sarcoma; Staining and Labeling

Topics: Acid Phosphatase; Adenoma, Chromophobe; Ameloblastoma; Astrocytoma; Biopsy; Brain; Brain Neoplasms; Cell Differentiation; Cerebellar Neoplasms; Cerebellum; Choroid Neoplasms; Choroid Plexus; Ependyma; Ependymoma; Esterases; Ganglia; Ganglioneuroma; Hemangiosarcoma; Histocytochemistry; Humans; Medulla Oblongata; Medulloblastoma; Meninges; Meningioma; Neuroectodermal Tumors, Primitive, Peripheral; Neuroma; Neurons; Oligodendroglioma; Pituitary Gland; Pituitary Neoplasms; Sarcoma

Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Brain Neoplasms; Disease Models, Animal; Enzymes; Esterases; Glioma; Glucuronidase; Histocytochemistry; Neoplasms, Experimental; Neurilemmoma; Nitroso Compounds; Oligodendroglioma; Rats

Topics: Acid Phosphatase; Alkaline Phosphatase; Aminopeptidases; Animals; Astrocytoma; Brain Neoplasms; Ependymoma; Esterases; Glioma; Histocytochemistry; Methylcholanthrene; Mice; Oligodendroglioma

Topics: Acid Phosphatase; Adenosine Triphosphatases; Alkaline Phosphatase; Astrocytoma; Brain Neoplasms; Carcinoma; Ependymoma; Esterases; Glioma; Glucosyltransferases; Histocytochemistry; Humans; Meningioma; Neurilemmoma; Oligodendroglioma; Sarcoma

Topics: Acid Phosphatase; Adenosine Triphosphate; Alkaline Phosphatase; Astrocytoma; Brain; Brain Neoplasms; Cerebellar Neoplasms; Dihydrolipoamide Dehydrogenase; Electron Transport Complex II; Ependyma; Esterases; Glioblastoma; Glucose-6-Phosphatase; Hemangiosarcoma; Histocytochemistry; Intracranial Arteriosclerosis; L-Lactate Dehydrogenase; NAD; NADP; Oligodendroglioma; Succinate Dehydrogenase

Topics: Acid Phosphatase; Alkaline Phosphatase; Astrocytoma; Brain; Brain Neoplasms; Esterases; Glioblastoma; Glioma; NAD; NADP; Neurochemistry; Oligodendroglioma; Oxidoreductases