acid-phosphatase and Mucocele

Ductal ligation of the sublingual gland induced mucocele formation in a high percentage of cats. Extravasated mucus was associated with all sublingual glands up to 20 days after ligation, and extravasation mucoceles were associated with 12 out of 27 sublingual glands between 7 and 365 days after ligation. Enzyme-histochemic examination revealed that the extravasated mucus induced a migration of macrophages and a fibroblastic reaction. It is thought that if these reactions are sufficiently intense in the early days after ligation, then continued spread of extravasated mucus and mucocele formation does not occur; however, if the extravasation is too great to be contained, a mucocele forms in which a balance develops between extravasation of mucus and its removal. Possibly the numerous macrophages in the mucoceles are involved in degrading mucus and facilitating its removal.

Topics: Acid Phosphatase; Aminopeptidases; Animals; Cats; Connective Tissue; Esterases; Glucuronidase; Leukocytes; Macrophages; Mucocele; Sublingual Gland; Time Factors

A survey of natural mucoceles revealed that there were two types, namely, extravasation and retention, and that extravasation mucocceles occurred most often in younger patients and in the lower lip, whereas retention mucoceles occurred most often in older patients and elsewhere in the mouth.

Topics: Acid Phosphatase; Adolescent; Adult; Aged; Aminopeptidases; Child; Child, Preschool; Epithelium; Esterases; Female; Fibroblasts; Glucuronidase; Histocytochemistry; Humans; Infant; Leukocytes; Macrophages; Male; Middle Aged; Mucocele; Salivary Gland Diseases

Topics: Acid Phosphatase; Animals; Cat Diseases; Cats; Collagen; Esterases; Glucuronidase; Histocytochemistry; Lysosomes; Macrophages; Male; Mucocele; Mucus; Salivary Gland Diseases; Vacuoles