acid-phosphatase and Meningeal-Neoplasms

In meningiomas extending into pericranial structures, phenomena of invasive growth are observed that have been little known up to now in this onkotype but are of differential diagnostic importance in these locations. 6 out of 10 meningiomas invading the ethmoidal sinus and/or skeletal muscles showed intravasal extension of tumour cells in small vessels of the neighbouring tissue. In 5 out of 7 cases with muscle invasion next to interstitial growth, the spreading of meningioma cells within isolated myofibers could be observed. As shown by enzyme- and immunohistochemical methods, the latter survived for a longer time in spite of active mitotic proliferation and axial spreading of the tumour cells within the sarcoplasm tube. A relation to peculiarities of histology, growth activity and clinical course does not seem to exist.

Topics: Acid Phosphatase; Adenosine Triphosphatases; Adult; Aged; Biomarkers; Biopsy; Dihydrolipoamide Dehydrogenase; Female; Head and Neck Neoplasms; Humans; Male; Meningeal Neoplasms; Meningioma; Middle Aged; Neck Muscles; Neoplasm Invasiveness; Retrospective Studies

Estimation of activity of five hydrolytic enzymes was made in foru histologically different types of human meningiomas derived from surgery. The hydrolytic enzymes examined in 13 tumors included four lysosomal enzymes: beta-glucuronidase, N-acetyl-beta-D-glucosaminidase (hexosaminidase), beta-galactosidase, and acid phosphatase. The fifth enzyme studied was alkaline phosphatase. The one papillary-type meningioma examined appeared to contain generally greater activities of the lysosomal enzymes than the other tumor types. Alkaline phosphatase was decidedly greater in transitional type meningiomas. The correlation of histological types with alkaline phosphatase activity is discussed with regard to previous observations.

Topics: Acid Phosphatase; Alkaline Phosphatase; Galactosidases; Glucuronidase; Hexosaminidases; Humans; Meningeal Neoplasms; Meningioma

A patient presenting with signs and symptoms attributable to meningeal carcinomatosis was found to have metastasizing prostatic carcinoma at autopsy. Microsopically, the primary and metastatic carcinomas exhibited mucus production. Only 3 cases of meningeal carcinomatosis owing to prostatic carcinoma are cited in the literature, none of which is documented adequately.

Topics: Acid Phosphatase; Adenocarcinoma; Aged; Humans; Male; Meningeal Neoplasms; Mucins; Prostatic Neoplasms

Topics: Acid Phosphatase; Aged; Basement Membrane; Central Nervous System Diseases; Desmosomes; Esterases; Female; Fibrosarcoma; Humans; Male; Meningeal Neoplasms; Microscopy, Electron; Middle Aged; Neoplasms, Radiation-Induced

Topics: Acetylglucosaminidase; Acid Phosphatase; Adult; Arylsulfatases; Child; Female; Glucuronidase; Humans; Lysosomes; Male; Meningeal Neoplasms; Meningioma

Topics: Acid Phosphatase; Alkaline Phosphatase; Cerebrospinal Fluid; Clinical Enzyme Tests; Esterases; Humans; Meningeal Neoplasms; Meningioma; Neoplasms

Topics: Acid Phosphatase; Alkaline Phosphatase; Aminopeptidases; Brain; Cerebellar Neoplasms; Esterases; Glioma; Medulloblastoma; Meningeal Neoplasms; Meningioma; Neoplasms, Nerve Tissue; Neurochemistry; Neurofibroma

Topics: Acid Phosphatase; Incidence; Meningeal Neoplasms; Meningioma; Phosphoric Monoester Hydrolases