acid-phosphatase has been researched along with Hemorrhagic-Disorders* in 4 studies
4 other study(ies) available for acid-phosphatase and Hemorrhagic-Disorders
| Article | Year |
|---|---|
High-fat Diet Enhances and Plasminogen Activator Inhibitor-1 Deficiency Attenuates Bone Loss in Mice with Lewis Lung Carcinoma.
This study determined the effects of a high-fat diet and plasminogen activator inhibitor-1 deficiency (Pai1(-/-)) on the bone structure in male C57BL/6 mice bearing Lewis lung carcinoma (LLC) in lungs. Significant reduction in bone volume fraction (BV/TV), trabecular number (Tb.N) and bone mineral density (BMD) in femurs and vertebrae were found in LLC-bearing mice compared to non-tumor-bearing mice. In LLC-bearing mice, the high-fat diet compared to the AIN93G control diet significantly reduced BV/TV, Tb.N and BMD in femurs and BV/TV in vertebrae. The high-fat diet significantly reduced BMD in vertebrae in wild-type mice but not in Pai1(-/-) mice. Compared to wild-type mice, PAI1 deficiency significantly increased BV/TV and Tb.N in femurs. The plasma concentration of osteocalcin was significantly lower and that of tartrate-resistant acid phosphatase 5b (TRAP5b) was significantly higher in LLC-bearing mice. The high-fat diet significantly reduced plasma osteocalcin and increased TRAP5b. Deficiency in PAI1 prevented the high-fat diet-induced increases in plasma TRAP5b. These findings demonstrate that a high-fat diet enhances, whereas PAI1 deficiency, attenuates metastasis-associated bone loss, indicating that a high-fat diet and PAI1 contribute to metastasis-associated bone deterioration. Topics: Acid Phosphatase; Animals; Bone and Bones; Bone Density; Carcinoma, Lewis Lung; Diet, High-Fat; Hemorrhagic Disorders; Isoenzymes; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Osteocalcin; Plasminogen Activator Inhibitor 1; Tartrate-Resistant Acid Phosphatase | 2015 |
Platelet dysfunction in glycogen storage disease type I.
Topics: Acid Phosphatase; Blood Coagulation Factors; Blood Coagulation Tests; Blood Platelet Disorders; Blood Platelets; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase Deficiency; Glycogen; Hemorrhagic Disorders; Humans; Metabolic Diseases; Microscopy, Electron; Platelet Adhesiveness | 1973 |
Studies on plasma thromboplastin antecedent (factor XI), PTA deficiency and inhibition of PTA by plasma: pharmacologic inhibitors and specific antiserum.
Topics: Acid Phosphatase; Adenosine Triphosphatases; Antigens; Blood Coagulation; Chromatography, Gel; Dialysis; Electrophoresis, Disc; Factor XI; Factor XI Deficiency; Hemorrhagic Disorders; Humans; Hydrogen-Ion Concentration; Immune Sera; Immunoelectrophoresis; Methods; Molecular Weight; Temperature; Triticum; Ultracentrifugation; Vegetables | 1972 |
[The uncommon course of promyelocytic leukemia. A contribution on the pathogenesis of hemorrhagic diathesis in acute promyelocytic leukemia].
Topics: Acid Phosphatase; Hemorrhagic Disorders; Humans; L-Lactate Dehydrogenase; Leukemia, Myeloid; Leukocytes; Leukopenia; Male; Middle Aged; Splenic Rupture | 1966 |