ach-702 has been researched along with Mycetoma* in 1 studies
1 other study(ies) available for ach-702 and Mycetoma
Article | Year |
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In vitro activity of ACH-702, a new isothiazoloquinolone, against Nocardia brasiliensis compared with econazole and the carbapenems imipenem and meropenem alone or in combination with clavulanic acid.
The in vitro activities of ACH-702 and other antimicrobials against 30 Nocardia brasiliensis isolates were tested. The MIC(50) (MIC for 50% of the strains tested) and MIC(90) values of ACH-702 were 0.125 and 0.5 microg/ml. The same values for econazole were 2 and 4 microg/ml. The MIC(50) and MIC(90) values of imipenem and meropenem were 64 and >64 microg/ml and 2 and 8 microg/ml, respectively; the addition of clavulanic acid to the carbapenems had no effect. Topics: Anti-Bacterial Agents; Clavulanic Acid; Drug Therapy, Combination; Econazole; Humans; Imipenem; In Vitro Techniques; Meropenem; Mycetoma; Nocardia; Nocardia Infections; Quinolones; Thiazoles; Thienamycins | 2010 |