acetylspiramycin and Chorioretinitis

Toxoplasma gondii is distributed worldwide, infecting a large population. It can cause focal necrotic retinitis or retinochoroiditis in the human eyes and is one of the most common causes of posterior uveitis.. A 68-year-old patient with normal immunity was complained about blurred vision and black shadow in the right eye for 1 week.. Combined Yellow-and-white bulged lesions in the fundus of the right eye with the Goldmann-Witmer coefficient = 2 and based on the serological indicators, we considered the diagnosis of T. gondii infection-induced retinochondritis.. Acetylspiramycin 0.4 QID × 3 weeks, concussive 20 days treatment after 3 days, for a total of 3 months, prednisone 20 mg/day with a weekly reduction of 5 mg for 1 month.. After oral acetylspiramycin, topical and systemic corticosteroids for 3 months, the retinal lesions were scarred, and inflammation of the anterior chamber and vitreum disappeared. After a 9-month follow-up, the visual acuity was 0.6, and no active lesions were observed in the fundus.. The immunocompetent elderly who are in contact with domestic cats may have an opportunistic infection with toxoplasmosis leading to primary retinochoroiditis. Prompt diagnosis and effective treatment can get a good clinical prognosis.

Topics: Aged; Animals; Anti-Bacterial Agents; Cats; Chorioretinitis; Diagnosis, Differential; Early Diagnosis; Fundus Oculi; Glucocorticoids; Humans; Male; Prednisone; Spiramycin; Toxoplasma; Toxoplasmosis, Ocular

Topics: Administration, Oral; Chorioretinitis; Coccidiostats; Endotamponade; Fluorescein Angiography; Humans; Male; Middle Aged; Retinal Perforations; Spiramycin; Sulfur Hexafluoride; Tomography, Optical Coherence; Toxoplasmosis, Ocular; Vision Disorders; Visual Acuity; Vitrectomy