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acetylhydrazine and Acute Liver Injury, Drug-Induced

acetylhydrazine has been researched along with Acute Liver Injury, Drug-Induced in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19904 (44.44)18.7374
1990's2 (22.22)18.2507
2000's2 (22.22)29.6817
2010's0 (0.00)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Huang, CH; Li, J; Li, PL; Li, R; Liu, CQ; Mao, L; Qin, L; Shao, B; Shao, J; Tang, TS; Xie, LN; Zhang, L; Zhao, CF; Zhu, BZ1
Chau, B; McQueen, CA; Richards, VE; White, MR1
Mashregi, M; O'Brien, PJ; Tafazoli, S1
Timbrell, JA; Wright, JM1
Timbrell, JA; Woodward, KN1
Bahri, AK; Chiang, CS; Timbrell, JA1
Folb, PI; Smith, P; Walubo, A1
Cheng, WB; Li, D; Wang, ZY; Zhang, RL1
Abramovich, AG; Koriakin, VA; Nikolaev, VP; Protopopova, MM; Sokolova, GB; Ziia, AV1

Other Studies

9 other study(ies) available for acetylhydrazine and Acute Liver Injury, Drug-Induced

ArticleYear
Molecular mechanism for the activation of the potent hepatotoxin acetylhydrazine: Identification of the initial N-centered radical and the secondary C-centered radical intermediates.
    Free radical biology & medicine, 2023, 08-01, Volume: 204

    Topics: Antitubercular Agents; Chemical and Drug Induced Liver Injury; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Hydrazines; Isoniazid

2023
Hepatic gene expression and lipid homeostasis in C57BL/6 mice exposed to hydrazine or acetylhydrazine.
    Toxicological sciences : an official journal of the Society of Toxicology, 2004, Volume: 82, Issue:1

    Topics: Administration, Oral; Animals; Carcinogens; Chemical and Drug Induced Liver Injury; Gene Expression; Gene Expression Profiling; Homeostasis; Hydrazines; Lipid Metabolism; Lipids; Liver; Male; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis; Organization and Administration; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2004
Role of hydrazine in isoniazid-induced hepatotoxicity in a hepatocyte inflammation model.
    Toxicology and applied pharmacology, 2008, May-15, Volume: 229, Issue:1

    Topics: Animals; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Hepatocytes; Hydrazines; Hydrogen Peroxide; In Vitro Techniques; Inflammation; Isoniazid; Lysosomes; Male; Membrane Potential, Mitochondrial; Oxidative Stress; Protein Carbonylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2008
Urinary metabolic profile of isoniazid in patients who develop isoniazid-related liver damage.
    Human toxicology, 1984, Volume: 3, Issue:6

    Topics: Acetylation; Adult; Aged; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Female; Humans; Hydrazines; Isoniazid; Kinetics; Male; Middle Aged; Phenotype

1984
Acetylhydrazine hepatotoxicity: the role of covalent binding.
    Toxicology, 1984, Feb-14, Volume: 30, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Hydrazines; Liver Diseases; Macromolecular Substances; Male; Necrosis; Phenobarbital; Protein Binding; Rats; Rats, Inbred Strains; Subcellular Fractions

1984
Acetylhydrazine hepatotoxicity.
    Toxicology and applied pharmacology, 1981, Sep-30, Volume: 60, Issue:3

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Hydrazines; Isoniazid; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains; Rifampin

1981
The role of oxygen free radicals in isoniazid-induced hepatotoxicity.
    Methods and findings in experimental and clinical pharmacology, 1998, Volume: 20, Issue:8

    Topics: Animals; Antitubercular Agents; Carcinogens; Chemical and Drug Induced Liver Injury; Hydrazines; Isoniazid; Lipid Peroxidation; Liver; Male; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

1998
Effects of rifampicin on pharmacokinetics of isoniazid and its metabolite acetylhydrazine in rats.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1992, Volume: 13, Issue:6

    Topics: Animals; Chemical and Drug Induced Liver Injury; Drug Interactions; Hydrazines; Isoniazid; Male; Rats; Rats, Wistar; Rifampin

1992
[Nonmedicinal prevention of liver involvement caused by isoniazid and monoacetylhydrazine in rats].
    Problemy tuberkuleza, 1987, Issue:12

    Topics: Animals; Chemical and Drug Induced Liver Injury; Female; Hydrazines; Isoniazid; Rats

1987