Page last updated: 2024-08-22

acetylglucosamine and Parkinson Disease

acetylglucosamine has been researched along with Parkinson Disease in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (60.00)24.3611
2020's4 (40.00)2.80

Authors

AuthorsStudies
Davey, AK; Kassiou, M; Mellick, GD; Rudrawar, S; Ryan, P; Xu, MM1
Galesic, A; Pratt, MR1
Hanover, JA; Jeong, H; Kim, BG; Kim, HB; Kim, HJ; Kim, HY; Kim, JI; Kwon, T; Lee, BE; Lee, HE; Lee, J; Lee, SE; Myung, K; Suh, PG; Yang, YR; Yi, EC1
Balana, AT; Pratt, MR1
Balana, A; De Leon, CA; Galesic, A; Levine, PM; Lewis, YE; Marotta, NP; Pratt, MR1
Hao, J; He, Y; Li, H; Ma, X1
Kalia, LV; Kalia, SK; O'Hara, DM1
Balana, AT; De Leon, CA; Galesic, A; Lashuel, HA; Levine, PM; Mahul-Mellier, AL; Navarro, MX; Pratt, MR1
Groves, JA; Lee, A; Yildirir, G; Zachara, NE1
Ambroso, MR; Arnold, DB; Langen, R; Lewis, YE; Lin, YH; Marotta, NP; Pratt, MR; Roth, MT; Zaro, BW1

Reviews

3 review(s) available for acetylglucosamine and Parkinson Disease

ArticleYear
Mechanistic roles for altered O-GlcNAcylation in neurodegenerative disorders.
    The Biochemical journal, 2021, 07-30, Volume: 478, Issue:14

    Topics: Acetylglucosamine; alpha-Synuclein; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Glycosylation; Humans; N-Acetylglucosaminyltransferases; Parkinson Disease; Protein Processing, Post-Translational; tau Proteins

2021
The emerging link between O-GlcNAcylation and neurological disorders.
    Cellular and molecular life sciences : CMLS, 2017, Volume: 74, Issue:20

    Topics: Acetylglucosamine; Acetylglucosaminidase; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Brain; Humans; N-Acetylglucosaminyltransferases; Nervous System Diseases; Neurons; Parkinson Disease; Protein Processing, Post-Translational; Proteins

2017
Emerging disease-modifying strategies targeting α-synuclein for the treatment of Parkinson's disease.
    British journal of pharmacology, 2018, Volume: 175, Issue:15

    Topics: Acetylglucosamine; Adrenergic beta-Agonists; alpha-Synuclein; Animals; Gastrointestinal Microbiome; Humans; Parkinson Disease

2018

Other Studies

7 other study(ies) available for acetylglucosamine and Parkinson Disease

ArticleYear
O-GlcNAcylation of truncated NAC segment alters peptide-dependent effects on α-synuclein aggregation.
    Bioorganic chemistry, 2020, Volume: 94

    Topics: Acetylglucosamine; alpha-Synuclein; Carbohydrate Conformation; Dose-Response Relationship, Drug; Glycosylation; Humans; Parkinson Disease; Protein Aggregates; Structure-Activity Relationship

2020
Investigating the Effects of O-GlcNAc Modifications in Parkinson's Disease Using Semisynthetic α-Synuclein.
    Methods in molecular biology (Clifton, N.J.), 2020, Volume: 2133

    Topics: Acetylglucosamine; alpha-Synuclein; Cysteine; Escherichia coli; Esters; Gene Expression; Glycosylation; Humans; Parkinson Disease; Peptide Biosynthesis; Peptides; Plasmids; Protein Engineering; Recombinant Proteins; Solid-Phase Synthesis Techniques; Sulfhydryl Compounds; Threonine

2020
O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.
    Brain : a journal of neurology, 2020, 12-01, Volume: 143, Issue:12

    Topics: Acetylglucosamine; Animals; Behavior, Animal; Cell Survival; Dopaminergic Neurons; Electrophysiological Phenomena; Female; Immunohistochemistry; Male; Mice; Movement Disorders; Neurodegenerative Diseases; Optogenetics; Parkinson Disease; Protein Modification, Translational; Synapses; Up-Regulation

2020
O-GlcNAc modification inhibits the calpain-mediated cleavage of α-synuclein.
    Bioorganic & medicinal chemistry, 2017, 09-15, Volume: 25, Issue:18

    Topics: Acetylglucosamine; alpha-Synuclein; Calpain; Escherichia coli; Humans; Parkinson Disease; Peptides; Protein Processing, Post-Translational; Proteolysis; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization

2017
α-Synuclein O-GlcNAcylation alters aggregation and toxicity, revealing certain residues as potential inhibitors of Parkinson's disease.
    Proceedings of the National Academy of Sciences of the United States of America, 2019, 01-29, Volume: 116, Issue:5

    Topics: Acetylglucosamine; Acylation; alpha-Synuclein; Animals; Cells, Cultured; Female; Mice; Mice, Inbred C57BL; Parkinson Disease; Pregnancy; Protein Aggregation, Pathological; Protein Processing, Post-Translational

2019
Dynamic O-GlcNAcylation and its roles in the cellular stress response and homeostasis.
    Cell stress & chaperones, 2013, Volume: 18, Issue:5

    Topics: Acetylglucosamine; Alzheimer Disease; Animals; beta-N-Acetylhexosaminidases; Calcium; Heat-Shock Proteins; Humans; Mitochondria; N-Acetylglucosaminyltransferases; Parkinson Disease; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction

2013
O-GlcNAc modification blocks the aggregation and toxicity of the protein α-synuclein associated with Parkinson's disease.
    Nature chemistry, 2015, Volume: 7, Issue:11

    Topics: Acetylglucosamine; Acylation; alpha-Synuclein; Humans; Parkinson Disease

2015