Page last updated: 2024-08-22

acetylglucosamine and Neurodegenerative Diseases

acetylglucosamine has been researched along with Neurodegenerative Diseases in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.00)18.2507
2000's4 (16.00)29.6817
2010's15 (60.00)24.3611
2020's5 (20.00)2.80

Authors

AuthorsStudies
Kim, JI; Lee, BE; Suh, PG1
Aggarwal, A; Cole, RN; Craven, M; Henry, RK; Jacobson, A; Kohr, MJ; Narayanan, B; O'Meally, RN; Reeves, RA; Umapathi, P; Zachara, NE; Zahra, F1
Arumugam, TV; Jo, DG; Lai, MKP; Park, J1
Hanover, JA; Jeong, H; Kim, BG; Kim, HB; Kim, HJ; Kim, HY; Kim, JI; Kwon, T; Lee, BE; Lee, HE; Lee, J; Lee, SE; Myung, K; Suh, PG; Yang, YR; Yi, EC1
Bellmann-Strobl, J; Brandt, AU; Chien, C; Demetriou, M; Dennis, JW; Dörr, J; Newton, BL; Paul, F; Pawling, J; Sy, M; Wuerfel, JT; Yu, Z; Zimmermann, HG1
Hsieh-Wilson, LC; Sorum, AW; Thompson, JW1
Danon, JJ; Davey, AK; Kassiou, M; Mellick, GD; Rudrawar, S; Ryan, P; Xu, M1
Nie, H; Yi, W1
Bond, MR; Hanover, JA1
Huang, J; Sun, C; Wang, M; Wu, B; Xian, H; Yang, Y; Zhao, J; Zheng, Y1
Vocadlo, DJ; Yuzwa, SA1
Banerjee, PS; Hart, GW; Lagerlöf, O1
Chatham, JC; Darley-Usmar, V; McMahon, LL; Wani, WY; Zhang, J1
Hsieh-Wilson, LC; Jensen, EH; Rexach, JE; Vinters, HV; Wang, AC1
Hanover, JA; Lazarus, BD; Love, DC1
Davies, GJ; Martinez-Fleites, C1
Hart, GW; Lagerlof, O; Ramirez-Correa, G; Slawson, C1
Chertov, AO; Couron, D; Holzhausen, L; Hurley, JB; Kuok, IT; Linton, JD; Parker, E; Sadilek, M; Sweet, IR1
Clark, T; Macauley, MS; Shan, X; Skorobogatko, Y; Vocadlo, DJ; Vosseller, K; Yuzwa, SA1
Forsythe, ME; Hanover, JA; Krause, MW; Lazarus, BD; Love, DC; Wang, P1
Gong, CX; Iqbal, K; Liu, F1
Beseme-Dekeyser, O; Dehennaut, V; Guinez, C; Lefebvre, T; Michalski, JC; Morelle, W1
Hanover, JA; Love, DC1
Gonzalez-Gomez, I; Groffen, J; Heisterkamp, N; Kaartinen, V; Mononen, I1
Hart, GW; Zachara, NE1

Reviews

13 review(s) available for acetylglucosamine and Neurodegenerative Diseases

ArticleYear
O-GlcNAcylation in health and neurodegenerative diseases.
    Experimental & molecular medicine, 2021, Volume: 53, Issue:11

    Topics: Acetylglucosamine; Aging; Animals; Biomarkers; Brain; Diagnosis, Differential; Disease Susceptibility; Gene Expression Regulation; Glycosylation; Homeostasis; Humans; Neurodegenerative Diseases; Neurons; Protein Processing, Post-Translational

2021
O-GlcNAcylation as a Therapeutic Target for Alzheimer's Disease.
    Neuromolecular medicine, 2020, Volume: 22, Issue:2

    Topics: Acetylglucosamine; Aged; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Antigens, Neoplasm; Brain; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucose; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing); Glycosylation; Hexosamines; Histone Acetyltransferases; Humans; Hyaluronoglucosaminidase; Insulin Resistance; Molecular Structure; Nerve Tissue Proteins; Neurodegenerative Diseases; Neuroprotective Agents; Phosphorylation; Protein Isoforms; Protein Processing, Post-Translational; Stroke; tau Proteins; Uridine Diphosphate; Uridine Diphosphate N-Acetylgalactosamine

2020
O-GlcNAcylation, a sweet link to the pathology of diseases.
    Journal of Zhejiang University. Science. B, 2019, Volume: 20, Issue:5

    Topics: Acetylglucosamine; Animals; Apoptosis; beta-N-Acetylhexosaminidases; Cardiovascular Diseases; Catalysis; Cell Nucleus; Cell Proliferation; Cytoplasm; Diabetes Complications; Diabetes Mellitus, Type 2; Hexosamines; Humans; Insulin; Mitochondria; N-Acetylglucosaminyltransferases; Neoplasms; Neurodegenerative Diseases; Phosphorylation; Protein Processing, Post-Translational; Signal Transduction

2019
O-GlcNAc cycling: a link between metabolism and chronic disease.
    Annual review of nutrition, 2013, Volume: 33

    Topics: Acetylglucosamine; Animals; beta-N-Acetylhexosaminidases; Diabetes Mellitus, Type 2; Diet; Energy Metabolism; Gene Expression Regulation; Health Status; Humans; N-Acetylglucosaminyltransferases; Neoplasms; Neurodegenerative Diseases; Protein Processing, Post-Translational; Protein Stability; Uridine Diphosphate N-Acetylglucosamine

2013
O-GlcNAc and neurodegeneration: biochemical mechanisms and potential roles in Alzheimer's disease and beyond.
    Chemical Society reviews, 2014, Oct-07, Volume: 43, Issue:19

    Topics: Acetylglucosamine; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antigens, Neoplasm; Histone Acetyltransferases; Humans; Hyaluronoglucosaminidase; N-Acetylglucosaminyltransferases; Neurodegenerative Diseases; tau Proteins

2014
Roles of O-GlcNAc in chronic diseases of aging.
    Molecular aspects of medicine, 2016, Volume: 51

    Topics: Acetylglucosamine; Aging; Chronic Disease; Diabetes Mellitus; Heart Diseases; Humans; Hyperglycemia; Inflammation; N-Acetylglucosaminyltransferases; Neoplasms; Neurodegenerative Diseases

2016
O-GlcNAcylation and neurodegeneration.
    Brain research bulletin, 2017, Volume: 133

    Topics: Acetylglucosamine; Acylation; Alzheimer Disease; Animals; beta-N-Acetylhexosaminidases; Brain; Glycoside Hydrolases; Glycosylation; Humans; N-Acetylglucosaminyltransferases; Neurodegenerative Diseases; Protein Processing, Post-Translational; Proteins

2017
O-GlcNAc cycling: implications for neurodegenerative disorders.
    The international journal of biochemistry & cell biology, 2009, Volume: 41, Issue:11

    Topics: Acetylglucosamine; Acetylglucosaminidase; Animals; Gene Expression Regulation; Glycosylation; Humans; N-Acetylglucosaminyltransferases; Neurodegenerative Diseases

2009
GlaxoSmithKline Award Lecture. The O-GlcNAc modification: three-dimensional structure, enzymology and the development of selective inhibitors to probe disease.
    Biochemical Society transactions, 2010, Volume: 38, Issue:5

    Topics: Acetylglucosamine; Animals; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Humans; N-Acetylglucosaminyltransferases; Neurodegenerative Diseases

2010
Cross talk between O-GlcNAcylation and phosphorylation: roles in signaling, transcription, and chronic disease.
    Annual review of biochemistry, 2011, Volume: 80

    Topics: Acetylglucosamine; Animals; Chronic Disease; Diabetes Mellitus; Glycosylation; Humans; Models, Molecular; Molecular Structure; N-Acetylglucosaminyltransferases; Neoplasms; Neurodegenerative Diseases; Phosphorylation; Protein Conformation; Signal Transduction; Transcription, Genetic

2011
Does O-GlcNAc play a role in neurodegenerative diseases?
    Expert review of proteomics, 2005, Volume: 2, Issue:2

    Topics: Acetylglucosamine; Acetylglucosaminidase; Animals; Brain; Glucose; Glycosylation; Humans; N-Acetylglucosaminyltransferases; Nerve Tissue Proteins; Neurodegenerative Diseases; Phosphorylation; Proteasome Endopeptidase Complex; Protein Folding; Protein Processing, Post-Translational; tau Proteins; Vesicular Transport Proteins

2005
The hexosamine signaling pathway: deciphering the "O-GlcNAc code".
    Science's STKE : signal transduction knowledge environment, 2005, Nov-29, Volume: 2005, Issue:312

    Topics: Acetylglucosamine; Acetylglucosaminidase; Animals; Antigens, Neoplasm; beta-N-Acetylhexosaminidases; Caenorhabditis elegans Proteins; Computational Biology; Diabetes Mellitus, Type 2; Genetic Predisposition to Disease; Hexosamines; Histone Acetyltransferases; Humans; Hyaluronoglucosaminidase; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Mammals; Mice; Mice, Transgenic; Multienzyme Complexes; N-Acetylglucosaminyltransferases; Neoplasm Proteins; Neurodegenerative Diseases; Plant Proteins; Protein Processing, Post-Translational; Signal Transduction; Stress, Physiological; Uridine Diphosphate N-Acetylglucosamine

2005
The emerging significance of O-GlcNAc in cellular regulation.
    Chemical reviews, 2002, Volume: 102, Issue:2

    Topics: Acetylglucosamine; Animals; Cell Physiological Phenomena; Diabetes Mellitus; Glycosylation; Humans; Neurodegenerative Diseases; Phosphorylation; Proteins

2002

Other Studies

12 other study(ies) available for acetylglucosamine and Neurodegenerative Diseases

ArticleYear
Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.
    Analytical biochemistry, 2023, 10-01, Volume: 678

    Topics: Acetylglucosamine; Animals; Antibodies; Contractile Proteins; Heart; Mammals; Mice; Neurodegenerative Diseases; Protein Processing, Post-Translational; Proteome

2023
O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.
    Brain : a journal of neurology, 2020, 12-01, Volume: 143, Issue:12

    Topics: Acetylglucosamine; Animals; Behavior, Animal; Cell Survival; Dopaminergic Neurons; Electrophysiological Phenomena; Female; Immunohistochemistry; Male; Mice; Movement Disorders; Neurodegenerative Diseases; Optogenetics; Parkinson Disease; Protein Modification, Translational; Synapses; Up-Regulation

2020
Association of a Marker of N-Acetylglucosamine With Progressive Multiple Sclerosis and Neurodegeneration.
    JAMA neurology, 2021, 07-01, Volume: 78, Issue:7

    Topics: Acetylglucosamine; Adult; Aged; Biomarkers; Case-Control Studies; Cohort Studies; Cross-Sectional Studies; Female; Germany; Humans; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Neurodegenerative Diseases; United States

2021
Deciphering the Functions of O-GlcNAc Glycosylation in the Brain: The Role of Site-Specific Quantitative O-GlcNAcomics.
    Biochemistry, 2018, 07-10, Volume: 57, Issue:27

    Topics: Acetylglucosamine; Animals; Brain; Brain Chemistry; Glycosylation; Humans; Memory; Neurodegenerative Diseases; Protein Processing, Post-Translational; Proteome; Proteomics; Tandem Mass Spectrometry

2018
O-GlcNAc Modification Protects against Protein Misfolding and Aggregation in Neurodegenerative Disease.
    ACS chemical neuroscience, 2019, 05-15, Volume: 10, Issue:5

    Topics: Acetylglucosamine; Animals; Brain; Humans; Neurodegenerative Diseases; Protein Aggregation, Pathological; Protein Folding; Protein Processing, Post-Translational

2019
MADP, a salidroside analog, protects hippocampal neurons from glutamate induced apoptosis.
    Life sciences, 2014, May-08, Volume: 103, Issue:1

    Topics: Acetylglucosamine; Animals; Apoptosis; bcl-2-Associated X Protein; Cell Survival; Cells, Cultured; Flow Cytometry; Glucosides; Glutamic Acid; Hippocampus; In Situ Nick-End Labeling; Mitogen-Activated Protein Kinases; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Phenols; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Signal Transduction

2014
Loss of O-GlcNAc glycosylation in forebrain excitatory neurons induces neurodegeneration.
    Proceedings of the National Academy of Sciences of the United States of America, 2016, 12-27, Volume: 113, Issue:52

    Topics: Acetylglucosamine; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain Mapping; Crosses, Genetic; Female; Glycosylation; Hippocampus; Humans; Inflammation; Male; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Acetylglucosaminyltransferases; Neurodegenerative Diseases; Neuroglia; Neurons; Phosphorylation; Prosencephalon; Signal Transduction; tau Proteins

2016
Roles of glucose in photoreceptor survival.
    The Journal of biological chemistry, 2011, Oct-07, Volume: 286, Issue:40

    Topics: Acetylglucosamine; Adenosine Triphosphate; Animals; Autophagy; Cell Death; Cell Survival; Gas Chromatography-Mass Spectrometry; Glucose; Lactic Acid; Mice; Mice, Inbred C57BL; Mitochondria; NAD; Neurodegenerative Diseases; Neurons; Oxygen Consumption; Photoreceptor Cells, Vertebrate; Retina

2011
Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation.
    Nature chemical biology, 2012, Feb-26, Volume: 8, Issue:4

    Topics: Acetylglucosamine; Adaptor Proteins, Signal Transducing; Alzheimer Disease; Animals; Carbohydrate Conformation; Disease Models, Animal; Enzyme Inhibitors; Female; Humans; Mice; Mice, Transgenic; N-Acetylglucosaminyltransferases; Neurodegenerative Diseases; Neurons; Phosphorylation; Pyrans; tau Proteins; Thiazoles

2012
O-GlcNAc cycling mutants modulate proteotoxicity in Caenorhabditis elegans models of human neurodegenerative diseases.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, Oct-23, Volume: 109, Issue:43

    Topics: Acetylglucosamine; Alleles; Animals; Caenorhabditis elegans; Disease Models, Animal; Humans; Mutation; Neurodegenerative Diseases; Proteolysis

2012
O-GlcNAc cycling modulates neurodegeneration.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, Oct-23, Volume: 109, Issue:43

    Topics: Acetylglucosamine; Animals; Caenorhabditis elegans; Disease Models, Animal; Humans; Mutation; Neurodegenerative Diseases

2012
Progressive neurodegeneration in aspartylglycosaminuria mice.
    The American journal of pathology, 1998, Volume: 153, Issue:4

    Topics: Acetylglucosamine; Animals; Aspartylglucosaminuria; Aspartylglucosylaminase; Central Nervous System; Cytoplasm; Female; Gait; Glial Fibrillary Acidic Protein; Immunoenzyme Techniques; Lysosomal Storage Diseases; Lysosomes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurodegenerative Diseases; Neurons; Urinary Bladder; Vacuoles

1998