Page last updated: 2024-08-22

acetylglucosamine and Disease Models, Animal

acetylglucosamine has been researched along with Disease Models, Animal in 103 studies

Research

Studies (103)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (0.97)	18.7374
1990's	10 (9.71)	18.2507
2000's	20 (19.42)	29.6817
2010's	63 (61.17)	24.3611
2020's	9 (8.74)	2.80

Authors

Authors	Studies
Arena, P; Attanasio, S; Boffa, I; Brunetti-Pierri, N; Cuomo, P; D'Alessio, AM; De Angelis, A; Desviat, LR; Ferenbach, AT; Häberle, J; Lipshutz, GS; Makris, G; Martínez-Pizarro, A; Motta, A; Nitzahn, M; Nusco, E; Paris, D; Pravata, VM; Richard, E; Rüfenacht, V; Soria, LR; van Aalten, DMF	1
Bakshi, S; Barnes, JW; Benavides, GA; Brahma, MK; Chang, SF; Chatham, JC; Curfman, S; Darley-Usmar, VM; Ha, CM; He, L; Lal, H; Paterson, AJ; Potter, LA; Rajasekaran, NS; Sun, Z; Sunny, S; Umbarkar, P; Wende, AR; Xie, M; Zhang, J; Zou, L	1
Feng, D; Sheng-Dong, L; Tong, W; Zhen-Xian, D	1
Popov, OS; Shebeko, SK; Zupanets, IA	1
Aillerie, V; Bigot, E; Cadiet, J; Chatham, JC; Denis, M; Erraud, A; Ferron, M; Gauthier, C; Lauzier, B; Mevel, M; Persello, A; Prat, V; Rozec, B	1
Arumugam, TV; Jo, DG; Lai, MKP; Park, J	1
Chatham, JC; Collins, HE	1
Fernandes, FF; Gonçales, RA; Pitangui, NS; Roque-Barreira, MC	1
Finkielsztein, S; Huegel, J; Nuss, CA; Soslowsky, LJ	1
Gao, F; Jiang, T; Jin, L; Li, C; Liu, B; Qin, X; Zheng, Q	1
Asahina, M; Fujinawa, R; Hirayama, H; Kajii, Y; Suzuki, T; Tozawa, R	1
Burtin, M; Dang, T; Delacour, D; Leffler, H; Magescas, J; Mayeux, A; Nilsson, UJ; Poirier, F; Sengmanivong, L; Terzi, F; Viau, A	1
Beaudry, F; Bernalier-Donadille, A; Garneau, P; Garrivier, A; Gobert, AP; Harel, J; Hay, AG; Jubelin, G; Le Bihan, G; Martin, C; Sicard, JF	1
Jiang, M; Li, Y; Liu, S; Paschen, W; Sheng, H; Warner, DS; Yang, W; Yu, S; Yu, Z	1
Johnsen, VL; Khan, A; Klein, MS; Newell, C; Rho, JM; Shearer, J; Xu, WJ; Yee, NC	1
Cao, L; Kim, G; Reece, EA; Zhao, Z	1
Audhya, A; Bisnett, BJ; Boyce, M; Chhetri, A; Condon, BM; Cox, NJ; Hanna, M; Knapik, EW; Luo, PM; Meister, TR; Smith, TJ; Soderblom, EJ; Unlu, G	1
Bi, Y; Chow, CY; Lowry, JB; Might, M; Owings, KG	1
Chen, KT; Cole, JN; Davies, MR; Henningham, A; Lund, S; Nizet, V; Uchiyama, S; van Sorge, NM; Walker, MJ	1
Chi, X; Ding, F; Wei, L; Xu, H; Yu, S	1
Chen, M; Chen, YF; Gong, K; Li, R; Oparil, S; Shen, H; Xu, L; Xu, O; Yao, D; Zhang, F; Zhang, Z; Zhu, H	1
Pier, GB; Zaidi, T; Zaidi, TS	1
Chatterjee, A; Feng, Y; Hammes, HP; Qiu, Y; Shan, S; Wieland, T	1
Barone, E; Butterfield, DA; Cassano, T; Castagnola, M; Castellani, A; Di Domenico, F; Gaetani, S; Iavarone, F; Lanzillotta, C; Perluigi, M; Sharma, N; Tramutola, A; Vincenzoni, F	1
Han, B; Jiang, Z; Li, Z; Liu, W; Peng, Y; Yang, Y; Zhang, W	1
Cheng, Q; Chi, X; Ding, F; Wei, L; Xu, H; Yang, Y; Yu, S; Zhou, C	1
Gao, M; Hao, X; He, L; Li, Y; Ma, J; Wang, J; Wei, H; Xiao, F; Yang, J; Ye, X; Zhao, S	1
Bøtker, HE; Hjortbak, MV; Jensen, RV; Jespersen, NR; Johnsen, J; Kristiansen, SB; Pryds, K; Pælestik, KB	1
Brünggel, K; Damo, M; Diaceri, G; Hirosue, S; Hubbell, JA; Quaglia-Thermes, X; Raczy, MM; Wilson, DS	1
Bernier, SG; Bryant, AP; Bueno, L; Currie, MG; Eutamene, H; Ge, P; Graul, C; Hannig, G; Jacobson, S; Jin, H; Kessler, MM; Kurtz, CB; Liong, E; Pezzone, MA; Reza, T; Rivers, S; Shea, C; Silos-Santiago, I; Tchernychev, B; Ustinova, EE	1
Cox, EJ; Marsh, SA	1
Aceves, S; Broide, DH; Cho, JY; Miller, M; Pham, A; Rosenthal, P; Sakuda, S	1
Carlson, GA; Dellovade, TL; Graham, DL; Gray, AJ; Hering, H; Joyce, JA; O'Moore, J; Shearman, MS; Yu, D	1
Capková, K; Danyi, I; Fišerová, A; Hříbalová, V; Malý, M; Richter, J; Vannucci, L	1
Gurel, Z; Pratt, MR; Sheibani, N; Zaro, BW	1
Abe, K; Deguchi, K; Deguchi, S; Ikeda, Y; Kono, S; Liu, N; Liu, W; Omote, Y; Yamashita, T; Yunoki, T	1
Azuma, K; Imagawa, T; Itoh, N; Kiyose, M; Kurozumi, S; Masuda, S; Minami, S; Okamoto, Y; Osaki, T; Sato, K; Tsuka, T	1
Abe, K; Deguchi, K; Hishikawa, N; Kono, S; Kurata, T; Omote, Y; Sato, K; Yamashita, T	1
Cao, C; Guan, G; Huang, G; Konopka, JB; Liang, W; Naseem, S; Tao, L; Wang, H; Wang, Y	1
Benetti, E; Chegaev, K; Chiazza, F; Collino, M; Cutrin, JC; Fruttero, R; Lazzarato, L; Rogazzo, M	1
Abdin, MZ; Datta, A; Datta, K; Kamthan, M; Majumdar, SS; Ruhela, D; Saha, P	1
Konopka, JB; Naseem, S	1
Cha, MY; Cho, HJ; Cho, JW; Choi, H; Choi, YJ; Dickson, DW; Hong, HS; Jin, SM; Jung, YO; Kang, MJ; Kim, C; Kim, DK; Kim, J; Mook-Jung, I; Murray, ME; Song, HK; Yi, EC	1
Abe, S; Ishijima, SA	1
Cassano, T; dos Santos, M; Gaetani, S; Gatta, E; Lefebvre, T; Maccari, S; Mairesse, J; Marrocco, J; Mir, AM; Nicoletti, F	1
Ding, F; Liu, X; Shen, Y; Xu, H; Yang, Y; Yu, S	1
Akman, YE; Çirci, E; Öztürkmen, Y; Şükür, E; Talu, C; Tüzüner, T	1
El-Agnaf, OM; Kawasaki, I; Kim, DK; Lee, HJ; Lee, SJ; Lim, HS; Shim, YH; Vaikath, NN	1
Brophy, PJ; Burlingame, AL; Kim, S; Maynard, JC; Milbrandt, J; Sasaki, Y; Sherman, DL; Strickland, A	1
Hebrink, DM; Jenson, PE; Kottom, TJ; Limper, AH; Ramirez-Prado, JH	1
Braem, A; Kucharíková, S; Mingeot-Leclercq, MP; Siala, W; Tulkens, PM; Van Bambeke, F; Van Dijck, P; Vleugels, J	1
Hao, J; He, Y; Li, D; Ma, X	1
Bozkurt-Guzel, C; Lederer, JA; Pier, GB; Priebe, GP; Zaidi, TH; Zaidi, TS; Zhao, G	1
Champattanachai, V; Chatham, JC; Chaudry, IH; Hu, S; Marchase, RB; Yang, S; Zou, L	1
Assmann, A; Carothers, A; Demcheva, M; Fischer, TH; Hechtman, HB; Matthews, J; Muise-Helmericks, RC; Orgill, DP; Perry, S; Pietramaggiori, G; Scherer, SS; Seth, A; Valeri, RC; Vournakis, JN	1
Buffone, A; Chandrasekaran, EV; Lau, JT; Locke, RD; Marathe, DD; Matta, KL; Nasirikenari, M; Neelamegham, S; Xue, J	1
Guven, Z; Ozkan, FU; Ozkan, K; Ramadan, S	1
Brocks, CA; Chatham, JC; Marchase, RB; Nöt, LG; Vámhidy, L	1
Dunder, U; Kelo, E; Mononen, I; Valtonen, P	1
Abe, K; Deguchi, K; Kawai, H; Liu, N; Lukic-Panin, V; Matsuura, T; Shang, J; Tian, F; Yamashita, T; Zhang, X	1
Fišerová, A; Grobárová, V; Hulíková, K; Křivohlavá, R	1
Andrade, SP; Ayres, E; Da Silva, GR; Da Silva-Cunha, A; Lima, LD; Moura, SA; Órefice, RL	1
Demcheva, M; Muise-Helmericks, RC; Seth, A; Vournakis, JN	1
Bronson, SK; Dennis, MD; Jefferson, LS; Kimball, SR; Schrufer, TL	1
Levit, RD; Taylor, WR	1
Abe, S; Cannon, RD; Hayama, K; Holmes, AR; Ishijima, SA; Takahashi, M	1
Bakker, SJ; Braunagel, M; Brinkkötter, P; Deinzer, M; Hammes, HP; Henning, RH; Koeppel, H; Krämer, BK; Navis, G; Pfister, F; Riedl, E; Sternik, P; van den Born, J; Yard, B	1
Clark, T; Macauley, MS; Shan, X; Skorobogatko, Y; Vocadlo, DJ; Vosseller, K; Yuzwa, SA	1
Chen, H; Endo, Y; Fujita, T; Hou, W; Jeza, VT; Pan, Q; Wang, F; Xiang, T; Zhang, XL; Zhao, Y; Zhu, Y	1
Azuma, K; Imagawa, T; Minami, S; Okamoto, Y; Osaki, T; Tsuka, T; Wakuda, T	1
Chatham, JC; Dell'italia, LJ; Marsh, SA; Powell, PC	1
Bentancor, LV; Bozkurt-Guzel, C; Cywes-Bentley, C; Maira-Litrán, T; O'Malley, JM; Pier, GB	1
Forsythe, ME; Hanover, JA; Krause, MW; Lazarus, BD; Love, DC; Wang, P	1
Gong, CX; Iqbal, K; Liu, F	1
Buus Kristiansen, S; Bøtker, HE; Johnsen, J; Vibjerg Jensen, R; Zachara, NE	1
DeMaria, TF; Grants, I; Liu, X; Tong, HH	1
Akimoto, Y; Hida, T; Hirano, H; Kawakami, H; Munetomo, E; Yamamoto, K	1
Ancsin, J; Bhat, S; Kisilevsky, R; Li, Z; Marone, S; Szarek, WA	1
Connolly, RJ	1
Bellinger, D; Chan, MW; Cole, DJ; Connolly, RJ; Nichols, T; Read, M; Schwaitzberg, SD	1
Hirabayashi, K; Jensen, DM; Machicado, GA	1
Favuzza, J; Hechtman, HB	1
Ancsin, J; Kisilevsky, R; Li, Z; Marone, S; Szarek, WA; Vohra, R	1
Ishibashi, Y; Itakura, T; Itoh, K; Kuroki, A; Kuwahara, J; Tsuji, D; Yamanaka, S	1
Becker, RE; Burnett, AL; Kramer, MF; Musicki, B	1
Breborowicz, A; Oreopoulos, DG; Połubinska, A; Tam, P; Wu, G	1
Ashwell, G; Forsythe, ME; Hanover, JA; Kim, EJ; Krause, MW; Lazarus, BD; Love, DC; Prinz, WA	1
Hascall, VC; Lauer, ME; Wang, A	1
Cerca, N; Goldmann, DA; Grout, M; Jefferson, KK; Maira-Litrán, T; Pier, GB	1
Alperovich, M; Chan, RK; Demcheva, M; Hechtman, HB; Kaipainen, A; Newalder, J; Orgill, DP; Pietramaggiori, G; Scherer, SS; Valeri, CR; Vournakis, JN; Yang, HJ	1
Crawford, GL; Hart, GW; Whiteheart, SW	1
Chatham, JC; Chen, YF; Feng, W; Majid-Hassan, E; Miller, AP; Nöt, LG; Oparil, S; Xing, D; Zhang, Y	1
Sly, WS	1
Gonzalez-Gomez, I; Groffen, J; Heisterkamp, N; Kaartinen, V; Mononen, I; Noronkoski, T; Voncken, JW	1
Bond, A; Hay, FC; Ratkay, LG; Waterfield, JD	1
Autti, T; Ginns, EI; Ikonen, S; Jalanko, A; Joensuu, R; LaMarca, ME; Manninen, T; McKinney, CE; Peltonen, L; Rapola, J; Riekkinen, P; Sipilä, I; Tenhunen, K	1
Azuma, I; Hiratai, R; Ishihara, C; Nose, M; Tsuji, M; Yagi, K	1
Gonzalez-Gomez, I; Groffen, J; Heisterkamp, N; Kaartinen, V; Mononen, I; Noronkoski, T	1
Demcheva, MV; Finkielsztein, S; Hawes, RH; Kulling, D; Rios, G; Tagge, DU; Vournakis, JN; Woo, S	1
Adams, DB; Baron, PL; Byrne, TK; Chan, MW; Cole, DJ; Connolly, RJ; Demcheva, M; Metcalf, JS; O'Brien, PH; Schwaitzberg, SD; Vournakis, J	1
Aronson, NN	1
Dawson, G; Huffman, PS; Jones, MZ; Thompson, JN	1
Bond, A; Cooke, A; Hay, FC	1

Reviews

5 review(s) available for acetylglucosamine and Disease Models, Animal

Article	Year
O-GlcNAcylation as a Therapeutic Target for Alzheimer's Disease. Neuromolecular medicine, 2020, Volume: 22, Issue:2 Topics: Acetylglucosamine; Aged; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Antigens, Neoplasm; Brain; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucose; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing); Glycosylation; Hexosamines; Histone Acetyltransferases; Humans; Hyaluronoglucosaminidase; Insulin Resistance; Molecular Structure; Nerve Tissue Proteins; Neurodegenerative Diseases; Neuroprotective Agents; Phosphorylation; Protein Isoforms; Protein Processing, Post-Translational; Stroke; tau Proteins; Uridine Diphosphate; Uridine Diphosphate N-Acetylgalactosamine	2020
Regulation of cardiac O-GlcNAcylation: More than just nutrient availability. Biochimica et biophysica acta. Molecular basis of disease, 2020, 05-01, Volume: 1866, Issue:5 Topics: Acetylglucosamine; Animals; Cardiovascular Diseases; Disease Models, Animal; Feeding Behavior; Heart; Humans; Myocardium; N-Acetylglucosaminyltransferases; Nutrients; Protein Processing, Post-Translational; Stress, Physiological	2020
Liquid Poly-N-acetyl Glucosamine (sNAG) Improves Achilles Tendon Healing in a Rat Model. Annals of biomedical engineering, 2021, Volume: 49, Issue:2 Topics: Acetylglucosamine; Achilles Tendon; Animals; Biomechanical Phenomena; Disease Models, Animal; Male; Rats, Sprague-Dawley; Tendon Injuries	2021
N-acetylglucosamine Regulates Virulence Properties in Microbial Pathogens. PLoS pathogens, 2015, Volume: 11, Issue:7 Topics: Acetylglucosamine; Animals; Bacteria; Disease Models, Animal; Fungi; Gene Expression; Humans; Virulence	2015
Aspartylglycosaminuria: biochemistry and molecular biology. Biochimica et biophysica acta, 1999, Oct-08, Volume: 1455, Issue:2-3 Topics: Acetylglucosamine; Amino Acid Sequence; Animals; Aspartylglucosylaminase; Base Sequence; Disease Models, Animal; DNA, Complementary; Evolution, Molecular; Finland; Gene Deletion; Gene Rearrangement; Glycoproteins; Humans; Lysosomal Storage Diseases; Lysosomes; Molecular Sequence Data; Mutation; Mutation, Missense	1999

Other Studies

98 other study(ies) available for acetylglucosamine and Disease Models, Animal

Article	Year
O-GlcNAcylation enhances CPS1 catalytic efficiency for ammonia and promotes ureagenesis. Nature communications, 2022, 09-05, Volume: 13, Issue:1 Topics: Acetylglucosamine; Ammonia; Animals; Biocatalysis; Carbamoyl-Phosphate Synthase (Ammonia); Disease Models, Animal; Glycosylation; Humans; Hyperammonemia; Mammals; Mice; N-Acetylglucosaminyltransferases; Propionic Acidemia; Protein Processing, Post-Translational; Urea; Uridine Diphosphate	2022
Sustained Increases in Cardiomyocyte Protein Journal of the American Heart Association, 2023, 10-03, Volume: 12, Issue:19 Topics: Acetylglucosamine; Animals; Cardiomegaly; Cardiovascular Diseases; Disease Models, Animal; Glycosylation; Mice; Mitochondria; Myocytes, Cardiac; N-Acetylglucosaminyltransferases; Protein Processing, Post-Translational	2023
O-GlcNAcylation of RAF1 increases its stabilization and induces the renal fibrosis. Biochimica et biophysica acta. Molecular basis of disease, 2020, 03-01, Volume: 1866, Issue:3 Topics: Acetylglucosamine; Acylation; Animals; Cell Line; Disease Models, Animal; Epithelial-Mesenchymal Transition; Fibrosis; Humans; Kidney Diseases; Male; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-raf; Rats; Rats, Sprague-Dawley; Signal Transduction; Ubiquitination; Ureteral Obstruction	2020
N-Acetylglucosamine is the most effective glucosamine derivative for the treatment of membranous nephropathy in rats. Die Pharmazie, 2019, 11-01, Volume: 74, Issue:11 Topics: Acetylglucosamine; Administration, Oral; Animals; Disease Models, Animal; Doxorubicin; Glomerulonephritis, Membranous; Injections, Intramuscular; Male; Rats	2019
O-GlcNAc stimulation: A new metabolic approach to treat septic shock. Scientific reports, 2019, 12-10, Volume: 9, Issue:1 Topics: Acetylglucosamine; Animals; beta-N-Acetylhexosaminidases; Bridged Bicyclo Compounds, Heterocyclic; Disease Models, Animal; Fluid Therapy; Humans; Lipopolysaccharides; Male; Protein Processing, Post-Translational; Rats; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Shock, Septic	2019
Paracoccin: Purification and Validation of Its Lectin and Enzymatic Properties. Methods in molecular biology (Clifton, N.J.), 2020, Volume: 2132 Topics: Acetylglucosamine; Animals; Chitinases; Disease Models, Animal; Fungal Proteins; Lectins; Mice; Paracoccidioides; Paracoccidioidomycosis; Protein Binding; Recombinant Proteins; Virulence Factors	2020
Hyper-O-GlcNAcylation impairs insulin response against reperfusion-induced myocardial injury and arrhythmias in obesity. Biochemical and biophysical research communications, 2021, 06-18, Volume: 558 Topics: Acetylglucosamine; Animals; Arrhythmias, Cardiac; Cardiotonic Agents; Cell Hypoxia; Cell Line; Diazooxonorleucine; Disease Models, Animal; Glycosylation; Humans; Insulin; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Myocardial Reperfusion Injury; Myocardium; Obesity; Protein Processing, Post-Translational; Rats	2021
Reversibility of motor dysfunction in the rat model of NGLY1 deficiency. Molecular brain, 2021, 06-13, Volume: 14, Issue:1 Topics: Acetylglucosamine; Animals; Congenital Disorders of Glycosylation; Disease Models, Animal; Genetic Therapy; Genetic Vectors; Gliosis; Humans; Inflammation; Injections, Intraventricular; Motor Activity; Neurons; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Rats; Rats, Transgenic; Transgenes	2021
Spindle pole cohesion requires glycosylation-mediated localization of NuMA. Scientific reports, 2017, 05-03, Volume: 7, Issue:1 Topics: Acetylglucosamine; Animals; Antigens, Nuclear; Blood Proteins; Cell Cycle Proteins; Cell Line; Disease Models, Animal; Epithelial Cells; Galectin 3; Galectins; Glycosylation; Humans; Interphase; Metaphase; Mice; Mice, Knockout; Nuclear Matrix-Associated Proteins; Protein Binding; Protein Processing, Post-Translational; Renal Insufficiency, Chronic; Spindle Poles	2017
The NAG Sensor NagC Regulates LEE Gene Expression and Contributes to Gut Colonization by Frontiers in cellular and infection microbiology, 2017, Volume: 7 Topics: Acetylglucosamine; Animals; Bacterial Adhesion; Bacteroides thetaiotaomicron; Cell Line; Disease Models, Animal; Enterohemorrhagic Escherichia coli; Epithelial Cells; Escherichia coli O157; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; HCT116 Cells; HeLa Cells; Humans; Intestines; Mice; Mice, Inbred BALB C; Mutation; N-Acetylneuraminic Acid; Operon; Phosphoproteins; Repressor Proteins	2017
XBP1 (X-Box-Binding Protein-1)-Dependent O-GlcNAcylation Is Neuroprotective in Ischemic Stroke in Young Mice and Its Impairment in Aged Mice Is Rescued by Thiamet-G. Stroke, 2017, Volume: 48, Issue:6 Topics: Acetylglucosamine; Age Factors; Animals; Brain Ischemia; Disease Models, Animal; Infarction, Middle Cerebral Artery; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuroprotection; Protein Folding; Protein Serine-Threonine Kinases; Pyrans; Stroke; Thiazoles; Unfolded Protein Response; X-Box Binding Protein 1	2017
Ketogenic diet leads to O-GlcNAc modification in the BTBR Biochimica et biophysica acta. Molecular basis of disease, 2017, Volume: 1863, Issue:9 Topics: Acetylglucosamine; Animals; Autistic Disorder; Diet, Ketogenic; Disease Models, Animal; Mice; Mice, Transgenic; Nerve Tissue Proteins; Prefrontal Cortex; Protein Processing, Post-Translational	2017
Impact of protein O-GlcNAcylation on neural tube malformation in diabetic embryopathy. Scientific reports, 2017, 09-11, Volume: 7, Issue:1 Topics: Acetylglucosamine; Animals; Apoptosis; Blood Glucose; Diabetes Complications; Disease Models, Animal; Endoplasmic Reticulum Stress; Enzyme Activation; Female; Glucose; Glycosylation; Maternal Exposure; Metabolic Networks and Pathways; Mice; N-Acetylglucosaminyltransferases; Neural Tube Defects; Pregnancy; Protein Processing, Post-Translational; Reactive Oxygen Species	2017
Dynamic Glycosylation Governs the Vertebrate COPII Protein Trafficking Pathway. Biochemistry, 2018, 01-09, Volume: 57, Issue:1 Topics: Acetylglucosamine; Acylation; Animals; Cell Line; Collagen; COP-Coated Vesicles; Craniofacial Abnormalities; Disease Models, Animal; Glycosylation; Humans; Organelles; Protein Conformation; Protein Processing, Post-Translational; Protein Transport; Vertebrates; Vesicular Transport Proteins; Zebrafish	2018
Transcriptome and functional analysis in a Drosophila model of NGLY1 deficiency provides insight into therapeutic approaches. Human molecular genetics, 2018, 03-15, Volume: 27, Issue:6 Topics: Acetylglucosamine; Animals; Congenital Disorders of Glycosylation; Developmental Disabilities; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Endoplasmic Reticulum; Endoplasmic Reticulum-Associated Degradation; Glycosylation; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Proteasome Endopeptidase Complex; Seizures; Sequence Analysis, RNA; Transcriptome	2018
Virulence Role of the GlcNAc Side Chain of the Lancefield Cell Wall Carbohydrate Antigen in Non-M1-Serotype Group A mBio, 2018, 01-30, Volume: 9, Issue:1 Topics: Acetylglucosamine; Animals; Antigens, Bacterial; Blood Bactericidal Activity; Cell Wall; Disease Models, Animal; Gene Deletion; Humans; Mice; Polysaccharides, Bacterial; Streptococcal Infections; Streptococcus pyogenes; Survival Analysis; Virulence; Virulence Factors	2018
2-(4-Methoxyphenyl)ethyl-2-acetamido-2-deoxy-β-D-pyranoside, an analog of salidroside, contributes to neuroprotection in cerebral ischemic injury in vitro and in vivo. Neuroreport, 2018, 03-21, Volume: 29, Issue:5 Topics: Acetylglucosamine; Animals; Apoptosis; Brain; Brain Ischemia; Capillary Permeability; Cell Hypoxia; Cell Survival; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose; Male; Neurons; Neuroprotective Agents; Primary Cell Culture; Random Allocation; Rats, Sprague-Dawley; Time Factors	2018
O-Linked β-N-Acetylglucosamine Modification of A20 Enhances the Inhibition of NF-κB (Nuclear Factor-κB) Activation and Elicits Vascular Protection After Acute Endoluminal Arterial Injury. Arteriosclerosis, thrombosis, and vascular biology, 2018, Volume: 38, Issue:6 Topics: Acetylglucosamine; Animals; Anti-Inflammatory Agents; Carotid Artery Injuries; Cell Proliferation; Cells, Cultured; Cytokines; Disease Models, Animal; DNA-Binding Proteins; Glucosamine; Glycosylation; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neointima; NF-kappa B; Rats, Sprague-Dawley; Signal Transduction; Tumor Necrosis Factor alpha-Induced Protein 3	2018
Antibodies to Conserved Surface Polysaccharides Protect Mice Against Bacterial Conjunctivitis. Investigative ophthalmology & visual science, 2018, 05-01, Volume: 59, Issue:6 Topics: Acetylglucosamine; Animals; Antibodies, Monoclonal; Bacterial Capsules; Conjunctivitis, Bacterial; Disease Models, Animal; Eye Infections, Bacterial; Female; Immunoglobulin G; Injections, Intraperitoneal; Mice; Mice, Inbred A; Mice, Inbred C57BL; Pneumococcal Infections; Polysaccharides, Bacterial; Staphylococcal Infections; Staphylococcus aureus; Streptococcus pneumoniae	2018
O-GlcNAcylation of FoxO1 mediates nucleoside diphosphate kinase B deficiency induced endothelial damage. Scientific reports, 2018, Jul-12, Volume: 8, Issue:1 Topics: Acetylglucosamine; Angiopoietin-2; Animals; Cell Nucleus; Diabetic Retinopathy; Disease Models, Animal; Endothelium, Vascular; Forkhead Box Protein O1; Gene Knockdown Techniques; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Knockout; NM23 Nucleoside Diphosphate Kinases; Primary Cell Culture; Retina; Retinal Vessels; RNA, Small Interfering; Up-Regulation	2018
Proteomic identification of altered protein O-GlcNAcylation in a triple transgenic mouse model of Alzheimer's disease. Biochimica et biophysica acta. Molecular basis of disease, 2018, Volume: 1864, Issue:10 Topics: Acetylglucosamine; Alzheimer Disease; Animals; beta-N-Acetylhexosaminidases; Brain; Disease Models, Animal; Female; Humans; Insulin Receptor Substrate Proteins; Male; Mice; Mice, Transgenic; N-Acetylglucosaminyltransferases; Phosphorylation; Proteins; Proteomics; Proto-Oncogene Proteins c-akt	2018
Dietary Natural Molecules (Basel, Switzerland), 2018, Sep-09, Volume: 23, Issue:9 Topics: Acetylglucosamine; Administration, Oral; Alkaline Phosphatase; Animals; Calcium; Cell Line; Dietary Supplements; Disease Models, Animal; Female; Femur; Humans; Mice; Osteoblasts; Osteogenesis; Osteoporosis, Postmenopausal; Ovariectomy; Rats; Rats, Sprague-Dawley; Tibia; Up-Regulation	2018
2-(4-Methoxyphenyl)ethyl-2-Acetamido-2-deoxy-β-d-pyranoside (A Salidroside Analog) Confers Neuroprotection with a Wide Therapeutic Window by Regulating Local Glucose Metabolism in a Rat Model of Cerebral Ischemic Injury. Neuroscience, 2018, 11-01, Volume: 391 Topics: Acetylglucosamine; Animals; Apoptosis; Brain Ischemia; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Glucose; Male; Neurons; Neuroprotective Agents; Rats, Sprague-Dawley; Stroke	2018
Deficient O-GlcNAc Glycosylation Impairs Regulatory T Cell Differentiation and Notch Signaling in Autoimmune Hepatitis. Frontiers in immunology, 2018, Volume: 9 Topics: Acetylglucosamine; Animals; Cell Differentiation; Concanavalin A; Disease Models, Animal; Gene Knockout Techniques; Glycosylation; Hepatitis, Autoimmune; Liver; Lymphocyte Activation; N-Acetylglucosaminyltransferases; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Receptors, Notch; Signal Transduction; T-Lymphocytes, Regulatory	2018
Impact of hyperglycemia on myocardial ischemia-reperfusion susceptibility and ischemic preconditioning in hearts from rats with type 2 diabetes. Cardiovascular diabetology, 2019, 05-31, Volume: 18, Issue:1 Topics: Acetylglucosamine; Animals; beta-N-Acetylhexosaminidases; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Ischemic Preconditioning, Myocardial; Isolated Heart Preparation; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Rats, Zucker	2019
Synthetically glycosylated antigens induce antigen-specific tolerance and prevent the onset of diabetes. Nature biomedical engineering, 2019, Volume: 3, Issue:10 Topics: Acetylgalactosamine; Acetylglucosamine; Adoptive Transfer; Animals; Antigen Presentation; Autoantigens; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Immune Tolerance; Liver; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, SCID; Spleen; T-Lymphocytes	2019
Gastrointestinal pain: unraveling a novel endogenous pathway through uroguanylin/guanylate cyclase-C/cGMP activation. Pain, 2013, Volume: 154, Issue:9 Topics: Acetylcholine; Acetylglucosamine; Adenocarcinoma; Animals; Cell Differentiation; Cell Line, Tumor; Colitis; Colon; Colorectal Neoplasms; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Female; Gastrointestinal Diseases; Gene Expression Regulation, Neoplastic; Guanylate Cyclase; Humans; Hyperalgesia; Intestinal Mucosa; Male; Mast Cells; Morphine; Multidrug Resistance-Associated Proteins; Natriuretic Peptides; Organic Anion Transporters, Sodium-Independent; Peroxidase; Rats; Rats, Sprague-Dawley; Rats, Wistar; Restraint, Physical; RNA, Messenger; Signal Transduction; Trinitrobenzenesulfonic Acid; Visceral Pain	2013
Exercise and diabetes have opposite effects on the assembly and O-GlcNAc modification of the mSin3A/HDAC1/2 complex in the heart. Cardiovascular diabetology, 2013, Jul-09, Volume: 12 Topics: Acetylglucosamine; Animals; Blood Glucose; Cardiomegaly; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Disease Models, Animal; Exercise Therapy; Gene Expression Regulation; Glycosylation; Histone Deacetylase 1; Histone Deacetylase 2; Mice, Inbred C57BL; Myocardium; N-Acetylglucosaminyltransferases; Obesity; Protein Processing, Post-Translational; Repressor Proteins; RNA, Messenger; Running; Sedentary Behavior; Sin3 Histone Deacetylase and Corepressor Complex; Time Factors	2013
Targeting AMCase reduces esophageal eosinophilic inflammation and remodeling in a mouse model of egg induced eosinophilic esophagitis. International immunopharmacology, 2014, Volume: 18, Issue:1 Topics: Acetylglucosamine; Allergens; Animals; Cells, Cultured; Chemokine CCL11; Chitinases; Disease Models, Animal; Eggs; Enzyme Inhibitors; Eosinophilic Esophagitis; Esophagus; Female; Fibrosis; Humans; Hyperplasia; Hypersensitivity, Immediate; Inflammation Mediators; Mice, Inbred BALB C; Molecular Targeted Therapy; Ovalbumin; Trisaccharides	2014
Increased O-GlcNAcylation reduces pathological tau without affecting its normal phosphorylation in a mouse model of tauopathy. Neuropharmacology, 2014, Volume: 79 Topics: Acetylglucosamine; Animals; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Disease Models, Animal; Female; Glycosylation; Male; Mice; Mice, Transgenic; Neurons; Neuroprotective Agents; Phosphorylation; Pyrans; tau Proteins; Tauopathies; Thiazoles	2014
Collagen-induced arthritis: severity and immune response attenuation using multivalent N-acetyl glucosamine. Clinical and experimental immunology, 2014, Volume: 177, Issue:1 Topics: Acetylglucosamine; Animals; Antigen-Presenting Cells; Arthritis, Experimental; Arthritis, Rheumatoid; B-Lymphocytes; Cell Differentiation; Cells, Cultured; Cytokines; Disease Models, Animal; Female; Humans; Killer Cells, Natural; Male; Mice; Mice, Inbred DBA; NK Cell Lectin-Like Receptor Subfamily K; Synovial Membrane; T-Lymphocytes	2014
Identification of O-GlcNAc modification targets in mouse retinal pericytes: implication of p53 in pathogenesis of diabetic retinopathy. PloS one, 2014, Volume: 9, Issue:5 Topics: Acetylglucosamine; Alloxan; Animals; Apoptosis; Diabetic Retinopathy; Disease Models, Animal; Endothelial Cells; Glucose; Glycosylation; Hyperglycemia; Mice; Pericytes; Retina; Tumor Suppressor Protein p53	2014
Pericyte protection by edaravone after tissue plasminogen activator treatment in rat cerebral ischemia. Journal of neuroscience research, 2014, Volume: 92, Issue:11 Topics: Acetylglucosamine; Animals; Antipyrine; Astrocytes; Brain Ischemia; Cell Proliferation; Disease Models, Animal; Edaravone; Free Radical Scavengers; Glial Cell Line-Derived Neurotrophic Factor; Glial Fibrillary Acidic Protein; Male; Pericytes; Quinolines; Rats; Rats, Wistar; Receptor, Platelet-Derived Growth Factor beta; Reperfusion; Time Factors; Tissue Plasminogen Activator	2014
Anti-tumor properties of orally administered glucosamine and N-acetyl-D-glucosamine oligomers in a mouse model. Carbohydrate polymers, 2014, Oct-13, Volume: 111 Topics: Acetylglucosamine; Administration, Oral; Animals; Antineoplastic Agents; Apoptosis; Colon; Colonic Neoplasms; Cytokines; Disease Models, Animal; Female; Glucosamine; Immunity, Innate; Interferon-gamma; Mice; Mice, Inbred BALB C	2014
Neurovascular protection by telmisartan via reducing neuroinflammation in stroke-resistant spontaneously hypertensive rat brain after ischemic stroke. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2015, Volume: 24, Issue:3 Topics: Acetylglucosamine; Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Carrier Proteins; Cerebral Cortex; Collagen Type IV; Disease Models, Animal; Encephalitis; Glial Fibrillary Acidic Protein; Hypertension; Infarction, Middle Cerebral Artery; Inflammasomes; Male; Matrix Metalloproteinase 9; Neuroprotective Agents; NLR Family, Pyrin Domain-Containing 3 Protein; Rats, Inbred SHR; Telmisartan; Time Factors	2015
The mitochondrial protein Mcu1 plays important roles in carbon source utilization, filamentation, and virulence in Candida albicans. Fungal genetics and biology : FG & B, 2015, Volume: 81 Topics: Acetylglucosamine; Amino Acids; Animals; Candida albicans; Candidemia; Carbon; Disease Models, Animal; Fungal Proteins; Gene Deletion; Hyphae; Mice; Mitochondrial Proteins; Multigene Family; Virulence	2015
A nitric oxide-donor furoxan moiety improves the efficacy of edaravone against early renal dysfunction and injury evoked by ischemia/reperfusion. Oxidative medicine and cellular longevity, 2015, Volume: 2015 Topics: Acetylglucosamine; Acute-Phase Proteins; Animals; Antipyrine; Creatinine; Disease Models, Animal; Edaravone; Free Radical Scavengers; Ischemia; Kidney; Lipid Peroxidation; Lipocalin-2; Lipocalins; Male; Malondialdehyde; Nitric Oxide Donors; Oxadiazoles; Oxidative Stress; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Reperfusion Injury; Urea	2015
In vivo role of Candida albicans β-hexosaminidase (HEX1) in carbon scavenging. MicrobiologyOpen, 2015, Volume: 4, Issue:5 Topics: Acetylglucosamine; Animals; beta-N-Acetylhexosaminidases; Candida albicans; Candidiasis; Carbon; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Hyaluronic Acid; Mice, Inbred BALB C; Virulence; Virulence Factors	2015
Mitochondrial ATP synthase activity is impaired by suppressed O-GlcNAcylation in Alzheimer's disease. Human molecular genetics, 2015, Nov-15, Volume: 24, Issue:22 Topics: Acetylglucosamine; Adenosine Triphosphate; Alzheimer Disease; Animals; beta-N-Acetylhexosaminidases; CHO Cells; Cricetulus; Disease Models, Animal; Glycosylation; HeLa Cells; Humans; Mice; Mice, Transgenic; Mitochondria; Mitochondrial Proton-Translocating ATPases; N-Acetylglucosaminyltransferases; Oxidative Phosphorylation Coupling Factors; Protein Processing, Post-Translational	2015
A Novel Murine Candidiasis Model with Severe Colonization in the Stomach Induced by N-acetylglucosamine-treatment and Its Scoring System Based on Local Characteristic Stomach Symptoms. Medical mycology journal, 2015, Volume: 56, Issue:4 Topics: Acetylglucosamine; Animals; Candida albicans; Candidiasis; Chlorpromazine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Female; Gastric Mucosa; Immunocompromised Host; Mice, Inbred ICR; Severity of Illness Index; Stomach Diseases	2015
Evidence for an imbalance between tau O-GlcNAcylation and phosphorylation in the hippocampus of a mouse model of Alzheimer's disease. Pharmacological research, 2016, Volume: 105 Topics: Acetylglucosamine; Acylation; Alzheimer Disease; Animals; Brain; Disease Models, Animal; Glycosylation; Hippocampus; Humans; Male; Mice; Mice, Transgenic; Phosphorylation; tau Proteins	2016
Therapeutic benefits of combined treatment with tissue plasminogen activator and 2-(4-methoxyphenyl)ethyl-2-acetamido-2-deoxy-β-d-pyranoside in an animal model of ischemic stroke. Neuroscience, 2016, 07-07, Volume: 327 Topics: Acetylglucosamine; Animals; Brain; Cerebral Hemorrhage; Combined Modality Therapy; Disease Models, Animal; Fibrinolytic Agents; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Rats, Sprague-Dawley; Recovery of Function; Stroke; Tissue Plasminogen Activator	2016
Comparison of the chondroprotective effect of a novel hydrogel compound and traditional hyaluronate on rat cartilage in a papain-induced osteoarthritis model. Acta orthopaedica et traumatologica turcica, 2016, Volume: 50, Issue:4 Topics: Acetylglucosamine; Animals; Cartilage, Articular; Disease Models, Animal; Female; Hyaluronic Acid; Hydrogels; Injections, Intra-Articular; Knee Joint; Osteoarthritis, Knee; Papain; Random Allocation; Rats; Rats, Sprague-Dawley	2016
Anti-aging treatments slow propagation of synucleinopathy by restoring lysosomal function. Autophagy, 2016, 10-02, Volume: 12, Issue:10 Topics: Acetylglucosamine; Aging; alpha-Synuclein; Animals; Caenorhabditis elegans; Disease Models, Animal; Endosomes; Humans; Lysosomes; Mutation; Polyubiquitin; Protein Aggregates; Transgenes; Ubiquitination	2016
Schwann Cell O-GlcNAc Glycosylation Is Required for Myelin Maintenance and Axon Integrity. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, 09-14, Volume: 36, Issue:37 Topics: Acetylglucosamine; Action Potentials; Animals; Autoimmune Diseases of the Nervous System; Axons; Disease Models, Animal; Gene Expression Regulation; Glucose; Glycosylation; Humans; Membrane Proteins; Mice; Mice, Transgenic; Myelin Basic Protein; Myelin Sheath; N-Acetylglucosaminyltransferases; Nerve Tissue Proteins; Neural Conduction; Proteomics; Sciatic Nerve; Tubulin	2016
Characterization of N-Acetylglucosamine Biosynthesis in Pneumocystis species. A New Potential Target for Therapy. American journal of respiratory cell and molecular biology, 2017, Volume: 56, Issue:2 Topics: Acetylglucosamine; Aminoglycosides; Animals; Biosynthetic Pathways; Blotting, Western; Cell Wall; Disease Models, Animal; Fluorescent Antibody Technique; Fungal Proteins; Gas Chromatography-Mass Spectrometry; Genes, Fungal; Lectins; Mice; Molecular Targeted Therapy; Pneumocystis; Pneumonia, Pneumocystis; Rats; RNA, Messenger	2017
The antifungal caspofungin increases fluoroquinolone activity against Staphylococcus aureus biofilms by inhibiting N-acetylglucosamine transferase. Nature communications, 2016, 11-03, Volume: 7 Topics: Acetylglucosamine; Animals; Antifungal Agents; Biofilms; Caspofungin; Disease Models, Animal; Drug Resistance, Bacterial; Drug Synergism; Echinocandins; Female; Fluoroquinolones; Humans; Lipopeptides; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; N-Acetylglucosaminyltransferases; Staphylococcal Infections; Staphylococcus aureus	2016
Thiamet G mediates neuroprotection in experimental stroke by modulating microglia/macrophage polarization and inhibiting NF-κB p65 signaling. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2017, Volume: 37, Issue:8 Topics: Acetylglucosamine; Acetylglucosaminidase; Animals; Biomarkers; Disease Models, Animal; Macrophages; Male; Mice, Inbred C57BL; Microglia; N-Acetylglucosaminyltransferases; Neuroprotective Agents; Pyrans; Signal Transduction; Stroke; Thiazoles; Transcription Factor RelA	2017
Efficacy of Antibody to PNAG Against Keratitis Caused by Fungal Pathogens. Investigative ophthalmology & visual science, 2016, 12-01, Volume: 57, Issue:15 Topics: Acetylglucosamine; Animals; Antilymphocyte Serum; Cornea; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Eye Infections, Fungal; Immunity, Cellular; Immunoglobulin G; Immunotherapy; Keratitis; Mice; Mice, Inbred C57BL	2016
Glucosamine improves cardiac function following trauma-hemorrhage by increased protein O-GlcNAcylation and attenuation of NF-{kappa}B signaling. American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:2 Topics: Acetylglucosamine; Acylation; Animals; Animals, Newborn; Cardiotonic Agents; Cells, Cultured; Disease Models, Animal; Glucosamine; Hemodynamics; I-kappa B Proteins; Intercellular Adhesion Molecule-1; Interleukin-6; Lipopolysaccharides; Macrophages; Male; Mice; Myocardial Contraction; Myocytes, Cardiac; N-Acetylglucosaminyltransferases; NF-kappa B; NF-KappaB Inhibitor alpha; Peroxidase; Phosphorylation; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Resuscitation; RNA Interference; RNA, Small Interfering; Shock, Hemorrhagic; Signal Transduction; Transfection; Tumor Necrosis Factor-alpha	2009
Poly-N-acetyl glucosamine nanofibers: a new bioactive material to enhance diabetic wound healing by cell migration and angiogenesis. Annals of surgery, 2009, Volume: 250, Issue:2 Topics: Absorbable Implants; Acetylglucosamine; Animals; Cell Culture Techniques; Cell Movement; Cell Proliferation; Diabetes Complications; Disease Models, Animal; Endothelial Cells; Male; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; Skin Ulcer; Tissue Scaffolds; Wound Healing	2009
Fluorinated per-acetylated GalNAc metabolically alters glycan structures on leukocyte PSGL-1 and reduces cell binding to selectins. Blood, 2010, Feb-11, Volume: 115, Issue:6 Topics: Acetylation; Acetylglucosamine; Animals; Blotting, Western; Bone Marrow Cells; Cell Adhesion; Cell Movement; Chemotaxis, Leukocyte; Disease Models, Animal; Flow Cytometry; Glycosylation; HL-60 Cells; Humans; Leukocytes; Lewis Blood Group Antigens; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Neoplasm Proteins; Peritonitis; Polysaccharides; Protein Binding	2010
Chondroprotective effect of N-acetylglucosamine and hyaluronate in early stages of osteoarthritis--an experimental study in rabbits. Bulletin of the NYU hospital for joint diseases, 2009, Volume: 67, Issue:4 Topics: Acetylglucosamine; Animals; Anterior Cruciate Ligament; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Hyaluronic Acid; Injections, Intra-Articular; Injections, Intramuscular; Knee Joint; Osteoarthritis, Knee; Rabbits; Range of Motion, Articular; Time Factors	2009
Increased O-linked beta-N-acetylglucosamine levels on proteins improves survival, reduces inflammation and organ damage 24 hours after trauma-hemorrhage in rats. Critical care medicine, 2010, Volume: 38, Issue:2 Topics: Acetylglucosamine; Animals; Apoptosis; Blood Gas Analysis; Blood Glucose; Blood Proteins; Cytokines; Disease Models, Animal; Hyperglycemia; Immunoblotting; Inflammation; Male; NF-kappa B; Peroxidase; Phosphorylation; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic	2010
Early initiation of enzyme replacement therapy improves metabolic correction in the brain tissue of aspartylglycosaminuria mice. Journal of inherited metabolic disease, 2010, Volume: 33, Issue:5 Topics: Acetylglucosamine; Age Factors; Animals; Animals, Newborn; Aspartylglucosaminuria; Aspartylglucosylaminase; Biomarkers; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Replacement Therapy; Humans; Injections, Intraperitoneal; Injections, Intravenous; Mice; Mice, Knockout; NIH 3T3 Cells; Recombinant Proteins; Time Factors; Transfection	2010
Free radical scavenger edaravone administration protects against tissue plasminogen activator induced oxidative stress and blood brain barrier damage. Current neurovascular research, 2010, Volume: 7, Issue:4 Topics: Acetylglucosamine; Animals; Antipyrine; Blood-Brain Barrier; Brain Injuries; Cerebral Cortex; Collagen Type IV; Disease Models, Animal; Drug Interactions; Edaravone; Endothelial Cells; Fibrinolytic Agents; Free Radical Scavengers; Gene Expression Regulation; In Vitro Techniques; Lipid Peroxidation; Male; Membrane Proteins; Nerve Tissue Proteins; Occludin; Oxidative Stress; Rats; Rats, Wistar; Tissue Plasminogen Activator	2010
Antitumor activity of N-acetyl-D-glucosamine-substituted glycoconjugates and combined therapy with keyhole limpet hemocyanin in B16F10 mouse melanoma model. Folia microbiologica, 2010, Volume: 55, Issue:5 Topics: Acetylglucosamine; Adjuvants, Immunologic; Animals; Antineoplastic Agents; Cell Line, Tumor; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Glycoconjugates; Hemocyanins; Humans; Male; Melanoma; Mice; Mice, Inbred C57BL; Skin Neoplasms; Treatment Outcome	2010
Local drug delivery system: inhibition of inflammatory angiogenesis in a murine sponge model by dexamethasone-loaded polyurethane implants. Journal of pharmaceutical sciences, 2011, Volume: 100, Issue:7 Topics: Acetylglucosamine; Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents; Biomarkers; Chemistry, Pharmaceutical; Collagen; Dexamethasone; Disease Models, Animal; Drug Carriers; Drug Compounding; Drug Implants; Female; Fibrosis; Hemoglobins; Inflammation; Macrophages; Mice; Neovascularization, Pathologic; Neutrophils; Peroxidase; Polyurethanes; Surgical Sponges; Technology, Pharmaceutical; Time Factors	2011
Poly-N-acetyl glucosamine fibers activate bone regeneration in a rabbit femur injury model. The Journal of trauma, 2011, Volume: 71, Issue:2 Suppl 1 Topics: Acetylglucosamine; Animals; Bone Regeneration; Disease Models, Animal; Femur; Male; Nanofibers; Osteoblasts; Rabbits	2011
Hyperglycemia-induced O-GlcNAcylation and truncation of 4E-BP1 protein in liver of a mouse model of type 1 diabetes. The Journal of biological chemistry, 2011, Sep-30, Volume: 286, Issue:39 Topics: Acetylglucosamine; Adaptor Proteins, Signal Transducing; Animals; Blood Glucose; Carrier Proteins; Cell Cycle Proteins; Diabetes Mellitus, Type 1; Disease Models, Animal; Eukaryotic Initiation Factors; Glycosylation; Hyperglycemia; Liver; Mice; Mice, Transgenic; Phlorhizin; Phosphoproteins	2011
A clinical commentary on the article "N-acetylglucosamine conjugated to nanoparticles enhances myocyte uptake and improves delivery of a small molecule p38 inhibitor for post-infarct healing" : N-acetylglucosamine conjugated nanoparticles: translational o Journal of cardiovascular translational research, 2011, Volume: 4, Issue:5 Topics: Acetylglucosamine; Animals; Cardiovascular Agents; Chemistry, Pharmaceutical; Disease Models, Animal; Drug Carriers; Drug Compounding; Imidazoles; Myocardial Infarction; Myocardium; Nanoparticles; p38 Mitogen-Activated Protein Kinases; Polymers; Protein Kinase Inhibitors; Pyrimidines; Regeneration	2011
N-acetylglucosamine increases symptoms and fungal burden in a murine model of oral candidiasis. Medical mycology, 2012, Volume: 50, Issue:3 Topics: Acetylglucosamine; Administration, Oral; Animals; Candida albicans; Candidiasis, Oral; Colony Count, Microbial; Disease Models, Animal; Female; Food; Histocytochemistry; Humans; Hyphae; Mice; Mice, Inbred ICR; Microscopy; Tongue; Virulence	2012
Carnosine prevents apoptosis of glomerular cells and podocyte loss in STZ diabetic rats. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2011, Volume: 28, Issue:2 Topics: Acetylglucosamine; Administration, Oral; Animals; Apoptosis; bcl-2-Associated X Protein; Carnosine; Cytochromes c; Diabetes Mellitus, Experimental; Disease Models, Animal; Glycation End Products, Advanced; Kidney Glomerulus; Oxidative Stress; Podocytes; Rats; Rats, Wistar; Reactive Oxygen Species; Streptozocin	2011
Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation. Nature chemical biology, 2012, Feb-26, Volume: 8, Issue:4 Topics: Acetylglucosamine; Adaptor Proteins, Signal Transducing; Alzheimer Disease; Animals; Carbohydrate Conformation; Disease Models, Animal; Enzyme Inhibitors; Female; Humans; Mice; Mice, Transgenic; N-Acetylglucosaminyltransferases; Neurodegenerative Diseases; Neurons; Phosphorylation; Pyrans; tau Proteins; Thiazoles	2012
L-ficolin binds to the glycoproteins hemagglutinin and neuraminidase and inhibits influenza A virus infection both in vitro and in vivo. Journal of innate immunity, 2012, Volume: 4, Issue:3 Topics: Acetylglucosamine; Animals; Cell Line; Complement Pathway, Mannose-Binding Lectin; Disease Models, Animal; Ficolins; Hemagglutinins; Humans; Influenza A virus; Lectins; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neuraminidase; Orthomyxoviridae Infections; Protein Binding; Transgenes; Virus Internalization	2012
Suppressive effects of N-acetyl-D-glucosamine on rheumatoid arthritis mouse models. Inflammation, 2012, Volume: 35, Issue:4 Topics: Acetylglucosamine; Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Disease Models, Animal; Female; Glucosamine; Interleukin-10; Interleukin-2; Interleukin-6; Joints; Mice; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha	2012
Cardiac O-GlcNAcylation blunts autophagic signaling in the diabetic heart. Life sciences, 2013, Mar-28, Volume: 92, Issue:11 Topics: Acetylglucosamine; Acylation; Animals; Arterial Pressure; Autophagy; Body Weight; Diabetic Cardiomyopathies; Disease Models, Animal; Hyperglycemia; Male; Myocytes, Cardiac; Random Allocation; Rats; Rats, Sprague-Dawley; Signal Transduction	2013
Synthesis and evaluation of a conjugate vaccine composed of Staphylococcus aureus poly-N-acetyl-glucosamine and clumping factor A. PloS one, 2012, Volume: 7, Issue:9 Topics: Acetylglucosamine; Animals; Antibodies, Bacterial; Antibody Specificity; Bacteremia; Chromatography, Gel; Coagulase; Cytotoxicity, Immunologic; Disease Models, Animal; Female; Fibrinogen; Goats; Immobilized Proteins; Immune Sera; Macaca mulatta; Mice; Microscopy, Confocal; Models, Immunological; Opsonin Proteins; Phagocytes; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Vaccines, Conjugate	2012
O-GlcNAc cycling mutants modulate proteotoxicity in Caenorhabditis elegans models of human neurodegenerative diseases. Proceedings of the National Academy of Sciences of the United States of America, 2012, Oct-23, Volume: 109, Issue:43 Topics: Acetylglucosamine; Alleles; Animals; Caenorhabditis elegans; Disease Models, Animal; Humans; Mutation; Neurodegenerative Diseases; Proteolysis	2012
O-GlcNAc cycling modulates neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America, 2012, Oct-23, Volume: 109, Issue:43 Topics: Acetylglucosamine; Animals; Caenorhabditis elegans; Disease Models, Animal; Humans; Mutation; Neurodegenerative Diseases	2012
Ischemic preconditioning increases myocardial O-GlcNAc glycosylation. Scandinavian cardiovascular journal : SCJ, 2013, Volume: 47, Issue:3 Topics: Acetylglucosamine; Alloxan; Animals; Azaserine; Disease Models, Animal; Glycosylation; Hemodynamics; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; N-Acetylglucosaminyltransferases; Rats; Rats, Wistar; Recovery of Function; Time Factors; Up-Regulation	2013
Comparison of alteration of cell surface carbohydrates of the chinchilla tubotympanum and colonial opacity phenotype of Streptococcus pneumoniae during experimental pneumococcal otitis media with or without an antecedent influenza A virus infection. Infection and immunity, 2002, Volume: 70, Issue:8 Topics: Acetylglucosamine; Animals; Carbohydrate Metabolism; Cell Membrane; Chinchilla; Disease Models, Animal; Ear, Middle; Eustachian Tube; Galactose; Humans; Influenza A virus; Influenza, Human; Lectins; Nasopharynx; Otitis Media; Peanut Agglutinin; Phenotype; Plant Lectins; Pneumococcal Infections; Sialic Acids; Streptococcus pneumoniae; Wheat Germ Agglutinins	2002
Elevated expression of O-GlcNAc-modified proteins and O-GlcNAc transferase in corneas of diabetic Goto-Kakizaki rats. Investigative ophthalmology & visual science, 2003, Volume: 44, Issue:9 Topics: Acetylglucosamine; Acetylglucosaminidase; Animals; beta-N-Acetylhexosaminidases; Cornea; Corneal Diseases; Diabetes Mellitus, Type 2; Disease Models, Animal; Enzyme Inhibitors; Fluorescent Antibody Technique, Indirect; Histone Acetyltransferases; In Situ Hybridization; Male; Multienzyme Complexes; N-Acetylglucosaminyltransferases; Organ Culture Techniques; Rabbits; Rats; Rats, Wistar; RNA Probes; RNA, Messenger	2003
Novel glycosaminoglycan precursors as anti-amyloid agents, part III. Journal of molecular neuroscience : MN, 2003, Volume: 20, Issue:3 Topics: Acetylglucosamine; Alzheimer Disease; Amyloid beta-Peptides; Animals; Basement Membrane; Brain; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Glycosaminoglycans; Golgi Apparatus; Heparan Sulfate Proteoglycans; Hepatocytes; Macrophages; Mice; Molecular Structure; Plaque, Amyloid	2003
Application of the poly-N-acetyl glucosamine-derived rapid deployment hemostat trauma dressing in severe/lethal Swine hemorrhage trauma models. The Journal of trauma, 2004, Volume: 57, Issue:1 Suppl Topics: Acetylglucosamine; Animals; Aorta, Abdominal; Aprotinin; Bandages; Blood Cell Count; Blood Volume; Chemistry, Pharmaceutical; Disease Models, Animal; Drug Combinations; Drug Evaluation, Preclinical; Femoral Artery; Fibrinogen; Hemorrhage; Hemostatic Techniques; Hemostatics; Military Medicine; Platelet Count; Survival Rate; Swine; Thrombin; Time Factors; Wounds, Penetrating	2004
Comparison of poly-N-acetyl glucosamine with commercially available topical hemostats for achieving hemostasis in coagulopathic models of splenic hemorrhage. The Journal of trauma, 2004, Volume: 57, Issue:1 Suppl Topics: Acetylglucosamine; Administration, Topical; Animals; Aprotinin; Body Temperature; Cellulose, Oxidized; Disease Models, Animal; Drug Combinations; Drug Evaluation, Preclinical; Female; Fibrin Foam; Fibrin Tissue Adhesive; Fibrinogen; Hemophilia B; Hemorrhage; Hemostatic Techniques; Hemostatics; Hypothermia, Induced; Rabbits; Spleen; Swine; Thrombin; Wounds, Penetrating	2004
Randomized double-blind studies of polysaccharide gel compared with glue and other agents for hemostasis of large veins and bleeding canine esophageal or gastric varices. The Journal of trauma, 2004, Volume: 57, Issue:1 Suppl Topics: Acetylglucosamine; Alcohols; Animals; Chemistry, Pharmaceutical; Disease Models, Animal; Dogs; Double-Blind Method; Drug Evaluation, Preclinical; Enbucrilate; Esophageal and Gastric Varices; Esophagoscopy; Gastrointestinal Hemorrhage; Gastroscopy; Gels; Hemostatic Techniques; Hemostatics; Hypertension, Portal; Oleic Acids; Random Allocation; Sclerosing Solutions; Sclerotherapy; Sodium Morrhuate; Wound Healing	2004
Hemostasis in the absence of clotting factors. The Journal of trauma, 2004, Volume: 57, Issue:1 Suppl Topics: Acetylglucosamine; Administration, Topical; Animals; Aorta, Abdominal; Azepines; Bandages; Disease Models, Animal; Drug Evaluation, Preclinical; Endothelin A Receptor Antagonists; Female; Hemorrhage; Hemostatic Techniques; Hemostatics; Male; Oligopeptides; Rats; Receptor, Endothelin A; Time Factors; Wounds, Penetrating	2004
Novel glycosaminoglycan precursors as antiamyloid agents: Part IV. Journal of molecular neuroscience : MN, 2004, Volume: 24, Issue:1 Topics: Acetylglucosamine; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Basement Membrane; Cell Adhesion; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Glycosaminoglycans; Heparan Sulfate Proteoglycans; Hepatocytes; Macrophages; Mice; Mice, Transgenic; Neuroprotective Agents; Protein Conformation	2004
Specific induction of macrophage inflammatory protein 1-alpha in glial cells of Sandhoff disease model mice associated with accumulation of N-acetylhexosaminyl glycoconjugates. Journal of neurochemistry, 2005, Volume: 92, Issue:6 Topics: Acetylglucosamine; Animals; Astrocytes; beta-N-Acetylhexosaminidases; Brain; Calcium-Binding Proteins; Chemokine CCL3; Chemokine CCL4; Chemokines; Disease Models, Animal; Disease Progression; G(M2) Ganglioside; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glycoconjugates; Hexosaminidase A; Hexosaminidase B; Macrophage Inflammatory Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Microfilament Proteins; Microglia; Neuroglia; Protein Subunits; RNA, Messenger; Sandhoff Disease; Up-Regulation	2005
Inactivation of phosphorylated endothelial nitric oxide synthase (Ser-1177) by O-GlcNAc in diabetes-associated erectile dysfunction. Proceedings of the National Academy of Sciences of the United States of America, 2005, Aug-16, Volume: 102, Issue:33 Topics: Acetylglucosamine; Animals; Diabetes Complications; Disease Models, Animal; Enzyme Activation; Erectile Dysfunction; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Penile Erection; Penis; Phosphorylation; Phosphoserine; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A	2005
N-acetylglucosamine reduces inflammatory response during acute peritonitis in uremic rats. Blood purification, 2006, Volume: 24, Issue:3 Topics: Acetylglucosamine; Acute Disease; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Glucose; Inflammation; Kinetics; Lipopolysaccharides; Male; Osmolar Concentration; Peritoneal Dialysis; Peritonitis; Rats; Rats, Wistar; Uremia	2006
Caenorhabditis elegans ortholog of a diabetes susceptibility locus: oga-1 (O-GlcNAcase) knockout impacts O-GlcNAc cycling, metabolism, and dauer. Proceedings of the National Academy of Sciences of the United States of America, 2006, Aug-08, Volume: 103, Issue:32 Topics: Acetylglucosamine; Acetylglucosaminidase; Alleles; Animals; Animals, Genetically Modified; beta-N-Acetylhexosaminidases; Caenorhabditis elegans; Disease Models, Animal; Hexosamines; Histone Acetyltransferases; Insulin; Insulin Resistance; Molecular Sequence Data; Multienzyme Complexes; Mutation; Phosphorylation; Signal Transduction	2006
Heparan sulfate analysis from diabetic rat glomeruli. The Journal of biological chemistry, 2007, Jan-12, Volume: 282, Issue:2 Topics: Acetylglucosamine; Albuminuria; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Disaccharides; Disease Models, Animal; Heparitin Sulfate; Kidney Glomerulus; Male; Oligosaccharides; Polysaccharide-Lyases; Rats; Rats, Sprague-Dawley; Sulfates	2007
Protection against Escherichia coli infection by antibody to the Staphylococcus aureus poly-N-acetylglucosamine surface polysaccharide. Proceedings of the National Academy of Sciences of the United States of America, 2007, May-01, Volume: 104, Issue:18 Topics: Acetylglucosamine; Animals; Antibodies, Bacterial; Disease Models, Animal; Escherichia coli; Escherichia coli Infections; Mice; Polysaccharides, Bacterial; Staphylococcus aureus	2007
Effects of poly-N-acetyl glucosamine (pGlcNAc) patch on wound healing in db/db mouse. The Journal of trauma, 2008, Volume: 64, Issue:3 Topics: Acetylglucosamine; Analysis of Variance; Animals; Bandages; Diabetes Mellitus, Experimental; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Skin; Wound Healing	2008
Murine platelets are not regulated by O-linked beta-N-acetylglucosamine. Archives of biochemistry and biophysics, 2008, Jun-01, Volume: 474, Issue:1 Topics: Acetylglucosamine; Animals; Blood Glucose; Blood Platelets; Blotting, Western; Diabetes Mellitus, Experimental; Disease Models, Animal; Mice; Mice, Inbred C57BL; Platelet Aggregation	2008
Increased protein O-GlcNAc modification inhibits inflammatory and neointimal responses to acute endoluminal arterial injury. American journal of physiology. Heart and circulatory physiology, 2008, Volume: 295, Issue:1 Topics: Acetylglucosamine; Animals; Anti-Inflammatory Agents; Carotid Arteries; Carotid Artery Injuries; Disease Models, Animal; Female; Glucosamine; Glycosylation; Inflammation Mediators; Monocytes; Neutrophil Infiltration; Ovariectomy; Oximes; Phenylcarbamates; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Time Factors	2008
Prospects for enzyme replacement for lysosomal storage diseases. Birth defects original article series, 1981, Volume: 17, Issue:1 Topics: Acetylglucosamine; Animals; Cell Membrane; Disease Models, Animal; Enzyme Therapy; Enzymes; Fibroblasts; Humans; Mannans; Mannosephosphates; Metabolism, Inborn Errors; Mononuclear Phagocyte System; Pinocytosis; Rats	1981
A mouse model for the human lysosomal disease aspartylglycosaminuria. Nature medicine, 1996, Volume: 2, Issue:12 Topics: Acetylglucosamine; Age Factors; Animals; Aspartylglucosaminuria; Aspartylglucosylaminase; Central Nervous System; Disease Models, Animal; Female; Humans; Lysosomal Storage Diseases; Lysosomes; Male; Mice; Mice, Knockout; Psychomotor Performance; RNA, Messenger; Stem Cells; Urinary Bladder	1996
Post-partum flare in MRL-lpr/lpr mice is associated with a parallel increase of N-acetylglucosamine on serum IgG. British journal of rheumatology, 1997, Volume: 36, Issue:2 Topics: Acetylglucosamine; Animals; Ankle Joint; Arthritis, Rheumatoid; Disease Models, Animal; Female; Galactose; Glycosylation; Hindlimb; Immunoglobulin G; Male; Mice; Mice, Inbred MRL lpr; Postpartum Period; Pregnancy	1997
Mice with an aspartylglucosaminuria mutation similar to humans replicate the pathophysiology in patients. Human molecular genetics, 1998, Volume: 7, Issue:2 Topics: Acetylglucosamine; Animals; Aspartylglucosaminuria; Aspartylglucosylaminase; Brain; Disease Models, Animal; Disease Progression; Gene Targeting; Genes, Recessive; Humans; Intellectual Disability; Liver; Lysosomal Storage Diseases; Magnetic Resonance Imaging; Maze Learning; Mice; Mice, Knockout; Microscopy, Electron; Phenotype	1998
Mannan decelerates the clearance of human red blood cells in SCID mouse. Immunopharmacology, 1998, Volume: 38, Issue:3 Topics: Acetylglucosamine; Animals; Candida; Chimera; Chitin; Disease Models, Animal; Erythrocyte Transfusion; Erythrocytes; Female; Glucose; Humans; Lactoferrin; Macrophages; Malaria, Falciparum; Male; Mannans; Mice; Mice, SCID; Phagocytosis; Receptors, Mitogen; Yeasts	1998
Phenotypic characterization of mice with targeted disruption of glycosylasparaginase gene: a mouse model for aspartylglycosaminuria. Journal of inherited metabolic disease, 1998, Volume: 21, Issue:3 Topics: Acetylglucosamine; Animals; Aspartylglucosylaminase; Disease Models, Animal; Gene Targeting; Lysosomal Storage Diseases; Mice; Phenotype	1998
Endoscopic injection of bleeding esophageal varices with a poly-N-acetyl glucosamine gel formulation in the canine portal hypertension model. Gastrointestinal endoscopy, 1999, Volume: 49, Issue:6 Topics: Acetylglucosamine; Animals; Disease Models, Animal; Dogs; Endosonography; Enzyme-Linked Immunosorbent Assay; Esophageal and Gastric Varices; Esophagoscopy; Female; Fluoroscopy; Gastrointestinal Hemorrhage; Gels; Homeostasis; Hypertension, Portal; Injections, Intralesional; Male; Treatment Outcome	1999
A pilot study evaluating the efficacy of a fully acetylated poly-N-acetyl glucosamine membrane formulation as a topical hemostatic agent. Surgery, 1999, Volume: 126, Issue:3 Topics: Acetylation; Acetylglucosamine; Administration, Topical; Adult; Animals; Digestive System Surgical Procedures; Disease Models, Animal; Female; Gastrointestinal Hemorrhage; Hemostatic Techniques; Hemostatics; Humans; Intestine, Small; Male; Pilot Projects; Polysaccharides; Postoperative Hemorrhage; Spleen; Swine	1999
N-acetylglucosamine 6-sulphatase deficiency in a Nubian goat: a model of Sanfilippo syndrome type D (mucopolysaccharidosis IIID). Journal of inherited metabolic disease, 1992, Volume: 15, Issue:5 Topics: Acetylglucosamine; Animals; Disease Models, Animal; Electrophoresis, Cellulose Acetate; Fibroblasts; Glycosaminoglycans; Goats; Male; Mucopolysaccharidosis III; Sulfatases; Sulfates	1992
Glycosylation of IgG, immune complexes and IgG subclasses in the MRL-lpr/lpr mouse model of rheumatoid arthritis. European journal of immunology, 1990, Volume: 20, Issue:10 Topics: Acetylglucosamine; Animals; Antigen-Antibody Complex; Arthritis, Rheumatoid; Carbohydrate Sequence; Disease Models, Animal; Galactose; Glycosylation; Immunoglobulin G; Lectins; Mice; Mice, Inbred Strains; Mice, Mutant Strains; Molecular Sequence Data; Oligosaccharides; Protein Processing, Post-Translational	1990