acetylglucosamine has been researched along with Diabetes Mellitus, Type 2 in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 12 (33.33) | 29.6817 |
| 2010's | 19 (52.78) | 24.3611 |
| 2020's | 5 (13.89) | 2.80 |
| Authors | Studies |
|---|---|
| Hatano, N; Hayami, T; Ogawa, W; Seino, S; Takahashi, H; Yokoi, N; Yoshida, M | 1 |
| Hayashi, T; Itoh, H; Jo, R; Kobayashi, S; Kurihara, I; Mitsuishi, Y; Murai-Takeda, A; Nakamura, T; Shibata, H; Yokota, K | 1 |
| Arumugam, TV; Jo, DG; Lai, MKP; Park, J | 1 |
| Fahie, K; Fernandes, SM; Hart, GW; Narayanan, B; Reeves, R; Zachara, NE; Zahra, F | 1 |
| Ameneiro, C; Beiroa, D; Bernardo, G; Bilbao, J; Bravo, SB; Carneiro, C; Cho, JW; Coppari, R; Cuñarro, J; Da Silva Lima, N; Dieguez, C; Dp Chantada-Vazquez, M; Fernandez, U; Fernández-Ramos, D; Ferno, J; Fidalgo, M; Fondevila, MF; Fruhbeck, G; Garcia-Vence, M; Gonzalez-Rellan, MJ; Guallar, D; Herzig, S; Iglesias, C; López, M; Lopitz-Otsoa, F; Martinez-Chantar, ML; Mato, JM; Millet, O; Müller, TD; Nogueiras, R; Novoa, E; Perez-Fernandez, R; Porteiro, B; Rodríguez, A; Sabio, G; Senra, A; Seoane, S; Tovar, S; Varela-Rey, M; Veyrat-Durebex, C; Vidal, A; Woodhoo, A; Yang, WH | 1 |
| Dai, W; Dennis, MD; Dierschke, SK; Toro, AL | 1 |
| Jaggi, AS; Singh, N; Tyagi, S; Virdi, JK | 1 |
| Nie, H; Yi, W | 1 |
| Bøtker, HE; Hjortbak, MV; Jensen, RV; Jespersen, NR; Johnsen, J; Kristiansen, SB; Pryds, K; Pælestik, KB | 1 |
| Bond, MR; Hanover, JA | 1 |
| Cox, EJ; Marsh, SA | 1 |
| Vaidyanathan, K; Wells, L | 1 |
| Hanover, JA; Olivier-Van Stichelen, S | 1 |
| Choi, JH; Choi, SS; Jang, HJ; Kim, IS; Koh, A; Lee, GH; Lee, H; Lee, YH; Park, D; Ryu, SH; Seo, YK; Suh, PG; Yang, YR | 1 |
| Escalante, A; Festa, A; Haffner, SM; Hanley, AJ; Lorenzo, C; Rewers, MJ | 1 |
| Chatham, JC; Cseh, J; Degrell, P; Fülöp, N; Mohás, M; Molnár, GA; Pajor, L; Wittmann, I | 1 |
| Hanover, JA; Krause, MW; Love, DC | 1 |
| Dehennaut, V; Drougat, L; Guinez, C; Lefebvre, T; Michalski, JC; Mir, AM; Mortuaire, M; Olivier, S; Vercoutter-Edouart, AS | 1 |
| Chatham, JC; Dell'Italia, LJ; Marsh, SA | 1 |
| Davies, GJ; Martinez-Fleites, C | 1 |
| Vosseller, K | 1 |
| Hart, GW; Vosseller, K; Zachara, NE | 1 |
| Kamata, K; Kobayashi, T; Matsumoto, T; Nemoto, S; Taguchi, K | 1 |
| Erasmus, RT; Essop, MF; Matsha, TE; Springhorn, C | 1 |
| Bøtker, HE; Jensen, RV; Kimose, HH; Kristiansen, SB; Nielsen, PH; Zachara, NE | 1 |
| Hilgertová, J; Prázný, M; Skrha, J; Weiserová, H | 1 |
| Hart, GW; Vosseller, K; Wells, L | 1 |
| Hart, GW; Wells, L | 1 |
| Akimoto, Y; Hida, T; Hirano, H; Kawakami, H; Munetomo, E; Yamamoto, K | 1 |
| Hart, GW; Zachara, NE | 1 |
| Hanover, JA; Love, DC | 1 |
| Chatham, JC; Fülöp, N; Marchase, RB | 1 |
| Chatham, JC; Davidoff, AJ; Dutta, K; Fülöp, N; Marchase, RB; Mason, MM; Wang, P | 1 |
| McNulty, PH | 1 |
| Kang, Y; Kim, Y; Kwon, H; Park, J | 1 |
| Bullen, JW; Copeland, RJ; Hart, GW | 1 |
15 review(s) available for acetylglucosamine and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
O-GlcNAcylation as a Therapeutic Target for Alzheimer's Disease.
Topics: Acetylglucosamine; Aged; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Antigens, Neoplasm; Brain; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucose; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing); Glycosylation; Hexosamines; Histone Acetyltransferases; Humans; Hyaluronoglucosaminidase; Insulin Resistance; Molecular Structure; Nerve Tissue Proteins; Neurodegenerative Diseases; Neuroprotective Agents; Phosphorylation; Protein Isoforms; Protein Processing, Post-Translational; Stroke; tau Proteins; Uridine Diphosphate; Uridine Diphosphate N-Acetylgalactosamine | 2020 |
Diabetes abolish cardioprotective effects of remote ischemic conditioning: evidences and possible mechanisms.
Topics: Acetylglucosamine; AMP-Activated Protein Kinases; Animals; Arginase; Autophagy; Beclin-1; Diabetes Mellitus, Type 2; Gene Expression Regulation; Humans; Ischemic Preconditioning, Myocardial; Myocardial Infarction; Myocardial Reperfusion Injury; Nitric Oxide; Oxidative Stress; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; rho-Associated Kinases; Signal Transduction; TOR Serine-Threonine Kinases | 2019 |
O-GlcNAcylation, a sweet link to the pathology of diseases.
Topics: Acetylglucosamine; Animals; Apoptosis; beta-N-Acetylhexosaminidases; Cardiovascular Diseases; Catalysis; Cell Nucleus; Cell Proliferation; Cytoplasm; Diabetes Complications; Diabetes Mellitus, Type 2; Hexosamines; Humans; Insulin; Mitochondria; N-Acetylglucosaminyltransferases; Neoplasms; Neurodegenerative Diseases; Phosphorylation; Protein Processing, Post-Translational; Signal Transduction | 2019 |
O-GlcNAc cycling: a link between metabolism and chronic disease.
Topics: Acetylglucosamine; Animals; beta-N-Acetylhexosaminidases; Diabetes Mellitus, Type 2; Diet; Energy Metabolism; Gene Expression Regulation; Health Status; Humans; N-Acetylglucosaminyltransferases; Neoplasms; Neurodegenerative Diseases; Protein Processing, Post-Translational; Protein Stability; Uridine Diphosphate N-Acetylglucosamine | 2013 |
Multiple tissue-specific roles for the O-GlcNAc post-translational modification in the induction of and complications arising from type II diabetes.
Topics: Acetylglucosamine; Animals; Diabetes Mellitus, Type 2; Humans; Insulin; Organ Specificity; Protein Processing, Post-Translational; Signal Transduction | 2014 |
You are what you eat: O-linked N-acetylglucosamine in disease, development and epigenetics.
Topics: Acetylglucosamine; Alzheimer Disease; Cardiovascular Diseases; Chromatin; Chronic Disease; Diabetes Mellitus, Type 2; Diet; Epigenesis, Genetic; Feeding Behavior; Female; Gene Expression Regulation; Genetic Loci; Genomic Imprinting; Homeostasis; Humans; Hypothalamo-Hypophyseal System; Lupus Erythematosus, Systemic; N-Acetylglucosaminyltransferases; Neoplasms; Neurogenesis; Obesity; Protein Processing, Post-Translational; X Chromosome Inactivation | 2015 |
The hexosamine signaling pathway: O-GlcNAc cycling in feast or famine.
Topics: Acetylglucosamine; Acetylglucosaminidase; Animals; Caenorhabditis elegans; Catalytic Domain; Diabetes Mellitus, Type 2; Evolution, Molecular; Food; Gene Expression Regulation; Humans; Insulin Resistance; MAP Kinase Signaling System; Models, Animal; Models, Molecular; N-Acetylglucosaminyltransferases; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-akt; Sirtuins; Starvation | 2010 |
Dysregulation of the nutrient/stress sensor O-GlcNAcylation is involved in the etiology of cardiovascular disorders, type-2 diabetes and Alzheimer's disease.
Topics: Acetylglucosamine; Alzheimer Disease; Animals; Basic Helix-Loop-Helix Transcription Factors; Brain; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Forkhead Box Protein O1; Forkhead Transcription Factors; Glucose; Homeodomain Proteins; HSP70 Heat-Shock Proteins; Humans; Insulin Resistance; Myocardial Reperfusion Injury; N-Acetylglucosaminyltransferases; Proteasome Endopeptidase Complex; Trans-Activators; Transcription Factors; Ubiquitins | 2010 |
GlaxoSmithKline Award Lecture. The O-GlcNAc modification: three-dimensional structure, enzymology and the development of selective inhibitors to probe disease.
Topics: Acetylglucosamine; Animals; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Humans; N-Acetylglucosaminyltransferases; Neurodegenerative Diseases | 2010 |
A role for N-acetylglucosamine as a nutrient sensor and mediator of insulin resistance.
Topics: Acetylglucosamine; Adipocytes; Animals; Diabetes Mellitus, Type 2; Forecasting; Glucose; Glycosylation; Hexosamines; Humans; Hyperglycemia; Insulin; Insulin Resistance; Models, Biological; Signal Transduction | 2003 |
O-GlcNAc turns twenty: functional implications for post-translational modification of nuclear and cytosolic proteins with a sugar.
Topics: Acetylglucosamine; Animals; Cell Nucleus; Cytosol; Diabetes Mellitus, Type 2; Glucose; Glycosylation; Hexosamines; Humans; Insulin; Models, Biological; Phosphorylation; Protein Processing, Post-Translational; Proteins; Signal Transduction; Transcription, Genetic | 2003 |
O-GlcNAc a sensor of cellular state: the role of nucleocytoplasmic glycosylation in modulating cellular function in response to nutrition and stress.
Topics: Acetylglucosamine; Acetylglucosaminidase; Animals; beta-N-Acetylhexosaminidases; Cell Death; Cell Nucleus; Cytoplasm; Diabetes Mellitus, Type 2; Glucose; Glycosylation; Histone Acetyltransferases; Humans; Multienzyme Complexes; Nutritional Physiological Phenomena; Phosphorylation; Proteins; Signal Transduction; Stress, Physiological | 2004 |
The hexosamine signaling pathway: deciphering the "O-GlcNAc code".
Topics: Acetylglucosamine; Acetylglucosaminidase; Animals; Antigens, Neoplasm; beta-N-Acetylhexosaminidases; Caenorhabditis elegans Proteins; Computational Biology; Diabetes Mellitus, Type 2; Genetic Predisposition to Disease; Hexosamines; Histone Acetyltransferases; Humans; Hyaluronoglucosaminidase; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Mammals; Mice; Mice, Transgenic; Multienzyme Complexes; N-Acetylglucosaminyltransferases; Neoplasm Proteins; Neurodegenerative Diseases; Plant Proteins; Protein Processing, Post-Translational; Signal Transduction; Stress, Physiological; Uridine Diphosphate N-Acetylglucosamine | 2005 |
Role of protein O-linked N-acetyl-glucosamine in mediating cell function and survival in the cardiovascular system.
Topics: Acetylglucosamine; Animals; Cardiovascular Diseases; Cell Survival; Diabetes Mellitus, Type 2; Glucose; Glycosylation; Hexosamines; Humans; Myocytes, Cardiac; Signal Transduction | 2007 |
Cross-talk between GlcNAcylation and phosphorylation: roles in insulin resistance and glucose toxicity.
Topics: Acetylglucosamine; Acetylglucosaminidase; Acylation; Amino Acid Sequence; Animals; Diabetes Mellitus, Type 2; Hexosamines; Humans; Insulin Resistance; Molecular Sequence Data; N-Acetylglucosaminyltransferases; Phosphorylation; Signal Transduction | 2008 |
21 other study(ies) available for acetylglucosamine and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
O-GlcNAcylation of myocyte-specific enhancer factor 2D negatively regulates insulin secretion from pancreatic β-cells.
Topics: Acetylglucosamine; Diabetes Mellitus, Type 2; Glucose; Humans; Incretins; Insulin Secretion; MEF2 Transcription Factors; Protein Processing, Post-Translational; Proteomics | 2022 |
Mechanisms of mineralocorticoid receptor-associated hypertension in diabetes mellitus: the role of O-GlcNAc modification.
Topics: Acetylglucosamine; Animals; Diabetes Mellitus, Type 2; Glucose; HEK293 Cells; Humans; Hypertension; Mice; Receptors, Mineralocorticoid | 2023 |
Detection and Analysis of Proteins Modified by O-Linked N-Acetylglucosamine.
Topics: Acetylglucosamine; Cell Nucleus; Diabetes Mellitus, Type 2; Glycosylation; Humans; Protein Processing, Post-Translational | 2021 |
O-GlcNAcylated p53 in the liver modulates hepatic glucose production.
Topics: Acetylglucosamine; Animals; Base Sequence; Caloric Restriction; Cell Line; Colforsin; Diabetes Mellitus, Type 2; Epinephrine; Glucagon; Glucocorticoids; Gluconeogenesis; Glucose; Glycosylation; Hepatocytes; Humans; Hydrocortisone; Hyperglycemia; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Liver; Mice, Inbred C57BL; Mice, Knockout; Obesity; Phosphoenolpyruvate Carboxykinase (GTP); Promoter Regions, Genetic; Protein Binding; Protein Stability; Pyruvic Acid; RNA, Messenger; Transcription, Genetic; Tumor Suppressor Protein p53 | 2021 |
Consumption of a high fat diet promotes protein O-GlcNAcylation in mouse retina via NR4A1-dependent GFAT2 expression.
Topics: Acetylglucosamine; Acylation; Animals; Cell Line; Ceramides; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Diet, High-Fat; Eye Proteins; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing); Humans; Male; Mice; Mice, Inbred C57BL; Nitrogenous Group Transferases; Nuclear Receptor Subfamily 4, Group A, Member 1; Palmitic Acid; Rats; Retina; Up-Regulation | 2018 |
Impact of hyperglycemia on myocardial ischemia-reperfusion susceptibility and ischemic preconditioning in hearts from rats with type 2 diabetes.
Topics: Acetylglucosamine; Animals; beta-N-Acetylhexosaminidases; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Ischemic Preconditioning, Myocardial; Isolated Heart Preparation; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Rats, Zucker | 2019 |
Exercise and diabetes have opposite effects on the assembly and O-GlcNAc modification of the mSin3A/HDAC1/2 complex in the heart.
Topics: Acetylglucosamine; Animals; Blood Glucose; Cardiomegaly; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Disease Models, Animal; Exercise Therapy; Gene Expression Regulation; Glycosylation; Histone Deacetylase 1; Histone Deacetylase 2; Mice, Inbred C57BL; Myocardium; N-Acetylglucosaminyltransferases; Obesity; Protein Processing, Post-Translational; Repressor Proteins; RNA, Messenger; Running; Sedentary Behavior; Sin3 Histone Deacetylase and Corepressor Complex; Time Factors | 2013 |
Obesity resistance and increased energy expenditure by white adipose tissue browning in Oga(+/-) mice.
Topics: Acetylglucosamine; Adipocytes, Brown; Adipose Tissue, Brown; Adipose Tissue, White; Animals; beta-N-Acetylhexosaminidases; Blood Glucose; Body Weight; Cell Differentiation; Diabetes Mellitus, Type 2; Energy Metabolism; Glucose Intolerance; Insulin Resistance; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; Signal Transduction; Thermogenesis | 2015 |
Novel Protein Glycan-Derived Markers of Systemic Inflammation and C-Reactive Protein in Relation to Glycemia, Insulin Resistance, and Insulin Secretion.
Topics: Acetylglucosamine; Biomarkers; Blood Glucose; Body Mass Index; C-Reactive Protein; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Galactosamine; Glucose Tolerance Test; Humans; Inflammation; Insulin; Insulin Resistance; Insulin Secretion; Linear Models; Magnetic Resonance Spectroscopy; Male; Middle Aged; Polysaccharides | 2017 |
Evidence of O-linked N-acetylglucosamine in diabetic nephropathy.
Topics: Acetylglucosamine; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Hypertrophy; Immunohistochemistry; Kidney; Male; N-Acetylglucosaminyltransferases | 2009 |
Activation of the hexosamine biosynthesis pathway and protein O-GlcNAcylation modulate hypertrophic and cell signaling pathways in cardiomyocytes from diabetic mice.
Topics: Acetylglucosamine; Animals; Biosynthetic Pathways; Cells, Cultured; Diabetes Mellitus, Type 2; Gene Expression; Glycosylation; Hexosamines; Humans; Hypertrophy; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Proteins; Signal Transduction | 2011 |
O-GlcNAc and aging: C. elegans as a genetic model to test O-GlcNAc roles in type II diabetic insulin resistance.
Topics: Acetylglucosamine; Aging; Animals; Caenorhabditis elegans; Diabetes Mellitus, Type 2; Insulin; Insulin Resistance; N-Acetylglucosaminyltransferases; Protein Processing, Post-Translational; Signal Transduction | 2010 |
Detection and analysis of proteins modified by O-linked N-acetylglucosamine.
Topics: Acetylglucosamine; Alzheimer Disease; Antibodies; beta-N-Acetylhexosaminidases; Cell Nucleus; Cells, Cultured; Diabetes Mellitus, Type 2; Glycosylation; Humans; N-Acetylglucosaminyltransferases; Protein Processing, Post-Translational; Proteins | 2011 |
Aminoguanidine normalizes ET-1-induced aortic contraction in type 2 diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rats by suppressing Jab1-mediated increase in ET(A)-receptor expression.
Topics: Acetylglucosamine; Animals; Aorta, Thoracic; Blood Glucose; Blood Pressure; COP9 Signalosome Complex; Diabetes Mellitus, Type 2; Dinoprostone; Endothelin-1; Endothelins; Extracellular Signal-Regulated MAP Kinases; Glycation End Products, Advanced; Guanidines; In Vitro Techniques; Insulin; Intracellular Signaling Peptides and Proteins; Male; Peptide Fragments; Phenylephrine; Phosphorylation; Proteins; Rats; Rats, Inbred OLETF; Receptor, Endothelin A; Receptor, Endothelin B; Vasoconstriction | 2012 |
Exploring leukocyte O-GlcNAcylation as a novel diagnostic tool for the earlier detection of type 2 diabetes mellitus.
Topics: Acetylglucosamine; Acylation; Blood Glucose; Diabetes Mellitus, Type 2; Early Diagnosis; Fasting; Female; Flow Cytometry; Glycated Hemoglobin; Glycosylation; Humans; Leukocytes; Male; Middle Aged; N-Acetylglucosaminyltransferases; Prediabetic State; Protein Processing, Post-Translational | 2012 |
Impact of O-GlcNAc on cardioprotection by remote ischaemic preconditioning in non-diabetic and diabetic patients.
Topics: Acetylglucosamine; Aged; beta-N-Acetylhexosaminidases; Diabetes Mellitus, Type 2; Female; Hemodynamics; Humans; Ischemic Preconditioning, Myocardial; Male; Middle Aged; N-Acetylglucosaminyltransferases | 2013 |
Serum alpha-tocopherol and ascorbic acid concentrations in Type 1 and Type 2 diabetic patients with and without angiopathy.
Topics: Acetylglucosamine; Adolescent; Adult; Antioxidants; Ascorbic Acid; Cholesterol; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Humans; Lipids; Male; Malondialdehyde; Oxidative Stress; Serum Albumin; Triglycerides; Vitamin E | 2003 |
Elevated expression of O-GlcNAc-modified proteins and O-GlcNAc transferase in corneas of diabetic Goto-Kakizaki rats.
Topics: Acetylglucosamine; Acetylglucosaminidase; Animals; beta-N-Acetylhexosaminidases; Cornea; Corneal Diseases; Diabetes Mellitus, Type 2; Disease Models, Animal; Enzyme Inhibitors; Fluorescent Antibody Technique, Indirect; Histone Acetyltransferases; In Situ Hybridization; Male; Multienzyme Complexes; N-Acetylglucosaminyltransferases; Organ Culture Techniques; Rabbits; Rats; Rats, Wistar; RNA Probes; RNA, Messenger | 2003 |
Impact of Type 2 diabetes and aging on cardiomyocyte function and O-linked N-acetylglucosamine levels in the heart.
Topics: Acetylglucosamine; Aging; Animals; Biomechanical Phenomena; Calcium; Diabetes Mellitus, Type 2; Glycosylation; Hyperglycemia; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Myocytes, Cardiac; N-Acetylglucosaminyltransferases; Rats; Rats, Sprague-Dawley; Rats, Zucker | 2007 |
Hexosamine biosynthetic pathway flux and cardiomyopathy in type 2 diabetes mellitus. Focus on "Impact of type 2 diabetes and aging on cardiomyocyte function and O-linked N-acetylglucosamine levels in the heart".
Topics: Acetylglucosamine; Aging; Animals; Biomechanical Phenomena; Calcium; Cardiomyopathies; Diabetes Mellitus, Type 2; Glycosylation; Hexosamines; Hyperglycemia; Myocardial Contraction; Myocardium; Myocytes, Cardiac; N-Acetylglucosaminyltransferases; Rats | 2007 |
Proteomic analysis of O-GlcNAc modifications derived from streptozotocin and glucosamine induced beta-cell apoptosis.
Topics: Acetylglucosamine; Animals; Apoptosis; Cell Line; Diabetes Mellitus, Type 2; Glucosamine; Glycosylation; Insulin; Insulin Secretion; Insulin-Secreting Cells; Models, Biological; Oximes; Phenylcarbamates; Proteomics; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Streptozocin | 2007 |