Page last updated: 2024-08-22

acetylglucosamine and Breast Cancer

acetylglucosamine has been researched along with Breast Cancer in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.00)18.7374
1990's2 (8.00)18.2507
2000's4 (16.00)29.6817
2010's14 (56.00)24.3611
2020's4 (16.00)2.80

Authors

AuthorsStudies
Abraham, JE; Caldas, C; Edwards, PAW; Flach, S; Laman, H; Manzano Garcia, R; Mason, B; Rueda, OM; Teixeira, FR1
Cho, JW; Ji, S; Kang, MJ; Kim, E; Kim, YJ; Kweon, TH; Park, YS; Yang, WH; Yi, EC1
Cao, L; Cheng, L; Dai, Z; Guan, F; Li, X; Song, Z; Tan, Z; Wang, B; Wu, Y; Yang, J; Yang, X; Zhou, X1
Chen, Q; Li, W; Liu, Y; Wang, L; Wu, Q; Xie, X; Zhang, J; Zhang, K; Zhang, N1
Gajbhiye, V; Kumar, P; Paknikar, KM; Tambe, P1
Chalise, P; D'Santos, CS; Goodman, ML; Hagan, CR; Madan, R; Papachristou, EK; Slawson, C; Trinca, GM1
Hagan, CR; Trinca, GM1
Chaiyawat, P; Champattanachai, V; Chokchaichamnankit, D; Lirdprapamongkol, K; Netsirisawan, P; Srisomsap, C; Svasti, J1
Chaiyawat, P; Champattanachai, V; Charoenwattanasatien, R; Chokchaichamnankit, D; Netsirisawan, P; Phueaouan, T; Punyarit, P; Srisomsap, C; Svasti, J1
Fardini, Y; Hampe, C; Issad, T; Kanwal, S; Masson, E; N'tumba-Byn, T; Pagesy, P; Pierre-Eugène, C1
Chen, W; Ding, J; Geng, M; Huang, M; Huang, X; Pan, Q; Shen, A; Sun, D1
Bissell, MJ; Nam, JM; Onodera, Y1
Falcone, JN; Ferrer, CM; Lynch, TP; Peacock, DL; Reginato, MJ; Schwab, LP; Seagroves, TN; Sodi, VL; Vocadlo, DJ1
Auvinen, P; Hämäläinen, K; Kosma, VM; Oikari, S; Rilla, K; Tammi, M; Tammi, R; Tiainen, S1
Caldwell, SA; Jackson, SR; Lynch, TP; Reginato, MJ; Sethi, G; Shahriari, KS; Vosseller, K; Walker, S1
Fan, Q; Ge, Y; Gu, Y; Han, C; Han, F; Liu, H; Lu, X; Mi, W; Yang, J; Yu, W1
Bernaciak, M; Bryś, M; Forma, E; Krześlak, A; Romanowicz, H1
Dwek, MV; Greenwell, P; Rambaruth, ND1
Bhujwalla, ZM; Glunde, K; Guggino, SE; Ichikawa, Y1
Cho, JW; Ju, JW; Kim, HS; Kim, JE; Kim, YS; Nam, HW; Yang, WH1
Davidson, EA; O'Connor, JV1
Bovin, NV; Rye, PD; Vlasova, EV; Walker, RA1
Bovin, NV; Fodstad, O; Høifødt, HK; Kierulf, B; Rye, PD; Trones, GE; Vlasova, E1
Brooks, SA; Carter, TM1
Pidala, J; Potter, R; Slawson, C1

Reviews

1 review(s) available for acetylglucosamine and Breast Cancer

ArticleYear
O-GlcNAcylation in women's cancers: breast, endometrial and ovarian.
    Journal of bioenergetics and biomembranes, 2018, Volume: 50, Issue:3

    Topics: Acetylglucosamine; Breast Neoplasms; Carcinogenesis; Endometrial Neoplasms; Female; Glycosylation; Humans; Neoplasms; Ovarian Neoplasms; Protein Processing, Post-Translational

2018

Trials

1 trial(s) available for acetylglucosamine and Breast Cancer

ArticleYear
N-acetylgalactosamine, N-acetylglucosamine and sialic acid expression in primary breast cancers.
    Acta histochemica, 2001, Volume: 103, Issue:1

    Topics: Acetylgalactosamine; Acetylglucosamine; Agglutinins; Breast Neoplasms; Female; Glycosylation; Histocytochemistry; Humans; Lectins; N-Acetylneuraminic Acid; Plant Lectins; Ribosome Inactivating Proteins; Soybean Proteins; Staining and Labeling

2001

Other Studies

23 other study(ies) available for acetylglucosamine and Breast Cancer

ArticleYear
Fbxl17 is rearranged in breast cancer and loss of its activity leads to increased global O-GlcNAcylation.
    Cellular and molecular life sciences : CMLS, 2020, Volume: 77, Issue:13

    Topics: Acetylglucosamine; Breast Neoplasms; Cell Line, Tumor; DNA Breaks; F-Box Proteins; Female; HEK293 Cells; Humans; Phosphorylation; Protein Processing, Post-Translational; Sequence Deletion; Ubiquitin-Protein Ligases; Ubiquitination

2020
O-GlcNAc stabilizes SMAD4 by inhibiting GSK-3β-mediated proteasomal degradation.
    Scientific reports, 2020, 11-16, Volume: 10, Issue:1

    Topics: Acetylglucosamine; Breast Neoplasms; Female; Glycogen Synthase Kinase 3 beta; Humans; Lung Neoplasms; Protein Processing, Post-Translational; Proteolysis; Serine; Signal Transduction; Smad4 Protein; Threonine; Transforming Growth Factor beta; Tumor Cells, Cultured; Ubiquitin

2020
Bisecting GlcNAc modification diminishes the pro-metastatic functions of small extracellular vesicles from breast cancer cells.
    Journal of extracellular vesicles, 2020, Volume: 10, Issue:1

    Topics: Acetylglucosamine; Breast Neoplasms; Cell Line, Tumor; Extracellular Vesicles; Female; Glycosylation; Humans; Integrin beta1; Neoplasm Metastasis; Neoplasm Proteins

2020
O-GlcNAc modification regulates MTA1 transcriptional activity during breast cancer cell genotoxic adaptation.
    Biochimica et biophysica acta. General subjects, 2021, Volume: 1865, Issue:8

    Topics: Acetylglucosamine; Apoptosis; Biomarkers, Tumor; Breast Neoplasms; Cell Proliferation; Chromatin; DNA Damage; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; N-Acetylglucosaminyltransferases; Prognosis; Protein Processing, Post-Translational; Repressor Proteins; Survival Rate; Trans-Activators; Tumor Cells, Cultured

2021
Folate/N-acetyl glucosamine conjugated mesoporous silica nanoparticles for targeting breast cancer cells: A comparative study.
    Colloids and surfaces. B, Biointerfaces, 2017, Aug-01, Volume: 156

    Topics: Acetylglucosamine; Antineoplastic Agents; Breast Neoplasms; Cell Proliferation; Dose-Response Relationship, Drug; Doxorubicin; Drug Screening Assays, Antitumor; Female; Folic Acid; Humans; Molecular Structure; Nanoparticles; Particle Size; Porosity; Silicon Dioxide; Structure-Activity Relationship; Surface Properties; Tumor Cells, Cultured

2017
O-GlcNAc-Dependent Regulation of Progesterone Receptor Function in Breast Cancer.
    Hormones & cancer, 2018, Volume: 9, Issue:1

    Topics: Acetylglucosamine; Acylation; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Female; Gene Regulatory Networks; Humans; MCF-7 Cells; N-Acetylglucosaminyltransferases; Protein Processing, Post-Translational; Receptors, Progesterone; Signal Transduction

2018
Decreasing O-GlcNAcylation affects the malignant transformation of MCF-7 cells via Hsp27 expression and its O-GlcNAc modification.
    Oncology reports, 2018, Volume: 40, Issue:4

    Topics: Acetylglucosamine; Anoikis; Apoptosis; Biomarkers, Tumor; Breast Neoplasms; Cell Proliferation; Cell Transformation, Neoplastic; Female; Glycosylation; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Humans; Molecular Chaperones; N-Acetylglucosaminyltransferases; Protein Processing, Post-Translational; Tumor Cells, Cultured

2018
Proteomic analysis and abrogated expression of O-GlcNAcylated proteins associated with primary breast cancer.
    Proteomics, 2013, Volume: 13, Issue:14

    Topics: Acetylglucosamine; Biomarkers, Tumor; Breast Neoplasms; Electrophoresis, Gel, Two-Dimensional; Female; Glycoproteins; Heterogeneous-Nuclear Ribonucleoproteins; Humans; Immunoblotting; Lactic Acid; Models, Biological; N-Acetylglucosaminyltransferases; Proteome; Reproducibility of Results

2013
O-GlcNAcylation-inducing treatments inhibit estrogen receptor α expression and confer resistance to 4-OH-tamoxifen in human breast cancer-derived MCF-7 cells.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Acetylglucosamine; Antineoplastic Agents, Hormonal; Biosynthetic Pathways; Breast Neoplasms; Cell Death; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Hexosamines; Humans; Insulin-Like Growth Factor I; MCF-7 Cells; Oximes; Phenylcarbamates; Phosphatidylinositol 3-Kinases; Promoter Regions, Genetic; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Selective Estrogen Receptor Modulators; Signal Transduction; Tamoxifen

2013
O-GlcNAcylation of cofilin promotes breast cancer cell invasion.
    The Journal of biological chemistry, 2013, Dec-20, Volume: 288, Issue:51

    Topics: Acetylglucosamine; Actin Depolymerizing Factors; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Female; Glycosylation; Humans; Mutation; N-Acetylglucosaminyltransferases; Neoplasm Invasiveness; Pseudopodia; Rats

2013
Increased sugar uptake promotes oncogenesis via EPAC/RAP1 and O-GlcNAc pathways.
    The Journal of clinical investigation, 2014, Volume: 124, Issue:1

    Topics: Acetylglucosamine; Adenylyl Cyclases; Biosynthetic Pathways; Breast Neoplasms; Carrier Proteins; Cell Line; Cell Transformation, Neoplastic; ErbB Receptors; Female; Glucose; Glucose Transporter Type 3; Glycolysis; Glycosylation; Guanine Nucleotide Exchange Factors; Humans; Integrin beta1; MAP Kinase Kinase Kinases; Membrane Proteins; Oncogenes; Oxygen Consumption; Phenotype; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Second Messenger Systems; Shelterin Complex; Telomere-Binding Proteins; Thyroid Hormone-Binding Proteins; Thyroid Hormones; Up-Regulation

2014
O-GlcNAcylation regulates cancer metabolism and survival stress signaling via regulation of the HIF-1 pathway.
    Molecular cell, 2014, Jun-05, Volume: 54, Issue:5

    Topics: Acetylglucosamine; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Citric Acid Cycle; Endoplasmic Reticulum Stress; Female; Glycolysis; Glycosylation; Humans; Hydroxylation; Hypoxia-Inducible Factor 1, alpha Subunit; Kaplan-Meier Estimate; Mice; Mice, Nude; N-Acetylglucosaminyltransferases; Neoplasm Transplantation; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Proteolysis; Signal Transduction; Transcription Factor CHOP

2014
High extent of O-GlcNAcylation in breast cancer cells correlates with the levels of HAS enzymes, accumulation of hyaluronan, and poor outcome.
    Breast cancer research and treatment, 2016, Volume: 160, Issue:2

    Topics: Acetylglucosamine; Adult; Aged; Aged, 80 and over; Biomarkers; Breast Neoplasms; Cell Nucleus; Cytoplasm; Female; Glycosylation; Humans; Hyaluronan Synthases; Hyaluronic Acid; Immunohistochemistry; Kaplan-Meier Estimate; Middle Aged; Neoplasm Grading; Neoplasm Metastasis; Neoplasm Staging; Obesity; Prognosis; Stromal Cells

2016
Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1.
    Oncogene, 2010, May-13, Volume: 29, Issue:19

    Topics: Acetylglucosamine; Animals; Base Sequence; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p27; Enzyme Inhibitors; Female; Forkhead Box Protein M1; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Matrix Metalloproteinase 2; Mice; N-Acetylglucosaminyltransferases; Neoplasm Invasiveness; Oncogene Proteins; Phenotype; Up-Regulation

2010
GlcNAcylation plays an essential role in breast cancer metastasis.
    Cancer research, 2010, Aug-01, Volume: 70, Issue:15

    Topics: Acetylglucosamine; Acylation; Animals; beta Catenin; Breast Neoplasms; Cadherins; Cell Line, Tumor; Cell Movement; Female; Glucosamine; Humans; Immunohistochemistry; Lung Neoplasms; Mice; Mice, Inbred BALB C

2010
Gene expression of O-GlcNAc cycling enzymes in human breast cancers.
    Clinical and experimental medicine, 2012, Volume: 12, Issue:1

    Topics: Acetylglucosamine; Adult; Aged; Antigens, Neoplasm; Breast Neoplasms; Enzyme Activation; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Histone Acetyltransferases; Humans; Hyaluronoglucosaminidase; Lymph Nodes; Middle Aged; N-Acetylglucosaminyltransferases; Neoplasm Grading; RNA, Messenger; Statistics, Nonparametric

2012
The lectin Helix pomatia agglutinin recognizes O-GlcNAc containing glycoproteins in human breast cancer.
    Glycobiology, 2012, Volume: 22, Issue:6

    Topics: Acetylglucosamine; Antibodies, Monoclonal; Breast Neoplasms; Female; Glycoproteins; Humans; Lectins; Tumor Cells, Cultured

2012
A novel method of imaging lysosomes in living human mammary epithelial cells.
    Molecular imaging, 2003, Volume: 2, Issue:1

    Topics: Acetylglucosamine; Antigens, CD; Breast; Breast Neoplasms; Cell Line; Dansyl Compounds; Epithelial Cells; Female; Fluorescent Dyes; Humans; Lysosomal Membrane Proteins; Lysosomes; Microscopy, Fluorescence; Tumor Cells, Cultured

2003
Modification of p53 with O-linked N-acetylglucosamine regulates p53 activity and stability.
    Nature cell biology, 2006, Volume: 8, Issue:10

    Topics: Acetylglucosamine; Breast Neoplasms; Cell Survival; Electrophoresis, Gel, Two-Dimensional; Humans; Immunoprecipitation; Lung Neoplasms; Phosphates; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-mdm2; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Ubiquitin

2006
Low-molecular-weight metabolites of D-[1-14C]glucosamine in cultured, normal and carcinomatous, human-mammary cells.
    Carbohydrate research, 1982, Jul-16, Volume: 105, Issue:2

    Topics: Acetylgalactosamine; Acetylglucosamine; Breast; Breast Neoplasms; Carbon Radioisotopes; Cells, Cultured; Chromatography, High Pressure Liquid; Female; Glucosamine; Humans

1982
Monoclonal antibody LU-BCRU-G7 against a breast tumour-associated glycoprotein recognizes the disaccharide Gal beta 1-3GlcNAc.
    Glycobiology, 1995, Volume: 5, Issue:4

    Topics: Acetylglucosamine; Antibodies, Monoclonal; Antibody Specificity; Antigens, Tumor-Associated, Carbohydrate; Breast Neoplasms; Carbohydrate Conformation; Carbohydrate Sequence; Disaccharides; Enzyme-Linked Immunosorbent Assay; Epitopes; Female; Galactose; Glycoproteins; Humans; Molecular Sequence Data; Molecular Structure; Protein Conformation; Tumor Cells, Cultured

1995
Breast cancer-associated antibody LU BCRU G7 recognises the terminal disaccharide Gal beta 1-3GlcNAc and can be used to isolate tumour cells from body fluids by an immunomagnetic bead procedure.
    Biochemical Society transactions, 1995, Volume: 23, Issue:4

    Topics: Acetylglucosamine; Antibodies, Monoclonal; Antibodies, Neoplasm; Antigens, Tumor-Associated, Carbohydrate; Body Fluids; Breast Neoplasms; Female; Humans; Immunomagnetic Separation

1995
Increased N-acetyl-beta-glucosaminidase activity in primary breast carcinomas corresponds to a decrease in N-acetylglucosamine containing proteins.
    Biochimica et biophysica acta, 2001, Sep-28, Volume: 1537, Issue:2

    Topics: Acetylglucosamine; Acetylglucosaminidase; Breast Neoplasms; Glycosylation; Humans; Hydrogen-Ion Concentration; Immunoblotting; Proteins; Up-Regulation

2001