Page last updated: 2024-08-22

acetylglucosamine and Aging

acetylglucosamine has been researched along with Aging in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19902 (7.41)18.7374
1990's3 (11.11)18.2507
2000's5 (18.52)29.6817
2010's12 (44.44)24.3611
2020's5 (18.52)2.80

Authors

AuthorsStudies
Kim, JI; Lee, BE; Suh, PG1
Desrouleaux, R; Lapenta, K; Li, MD; Liu, J; Wu, J; Yang, X1
Demetriou, M; Dennis, JW; Gong, AD; Grigoryan, D; Hai, JL; Hayama, KL; Khachikyan, K; Klaus, S; Lee, PL; Li, C; Ly, KM; Mkhikian, H; Newton, BL; Pawling, J; Raffatellu, M; Saryan, H; Tran, PQN; Zhou, RW1
Albarran, E; Bieri, G; Ding, JB; Pratt, K; Sanchez-Diaz, C; Snethlage, CE; Villeda, SA; Wheatley, EG; White, CW1
Alonso, J; Brooks, SP; Heck, AJR; Hills, R; Leney, AC; McCrimmon, RJ; McNeilly, AD; McWilliams, TG; Muha, V; Read, KD; Schimpl, M; Sutherland, C; van Aalten, DMF; Williamson, R1
Bagul, HP; Budnar, S; Chakraborty, A; Chattopadhyay, T; Kamat, SS; Kolthur-Seetharam, U; Maniyadath, B; Rajendran, A; Shukla, A; Shukla, N1
Chen, J; Cheng, X; Dong, X; Guo, W; Huang, X; Li, L; Li, Q; Li, X; Shu, Q; Sun, B; Wang, M; Yi, W; Zhang, J; Zhu, Q1
Davern, KM; Krištić, J; Lauc, G; Morahan, G; Nguyen, Q; Novokmet, M; Pezer, M; Ram, R; Trbojević-Akmačić, I; Vilaj, M; Vučković, F; Zaytseva, OO1
Crowley, SD; Ding, F; Paschen, W; Ren, J; Shen, Y; Sheng, H; Wang, W; Wang, Z; Wu, J; Yan, B; Yang, W; Yu, S; Zhao, Q1
Gurel, Z; Shallow, KD; Sheibani, N; Sieg, KM; Sorenson, CM1
Liu, S; Paschen, W; Sheng, H; Yang, W; Yu, Z1
Abdulhamid, S; Alejandro, EU; Arvan, P; Bernal-Mizrachi, E; Bozadjieva, N; Haataja, L; Kumusoglu, D; Levine, H; Satin, LS; Vadrevu, S1
Banerjee, PS; Hart, GW; Lagerlöf, O1
El-Agnaf, OM; Kawasaki, I; Kim, DK; Lee, HJ; Lee, SJ; Lim, HS; Shim, YH; Vaikath, NN1
Vosseller, K1
Cooksey, RC; Jones, D; Luo, B; McClain, DA; Parker, G; Soesanto, Y1
Chen, CC; Ding, N; Li, Y; Liang, X; Liu, X; Nie, H; Qu, Y; Sun, W; Sun, X; Yao, Y1
Chatham, JC; Davidoff, AJ; Dutta, K; Fülöp, N; Marchase, RB; Mason, MM; Wang, P1
McNulty, PH1
Brocks, CA; Chatham, JC; Feng, W; Fülöp, N; He, K; Marchase, RB; Miller, AP; Nőt, LG; Xing, D1
Bower, LM; Warren, C; Wilkinson, CR1
Kagayama, M; Mayanagi, H; Sasano, Y; Sato, H; Zhu, JX1
Bollinger, RR; Lee, W; Love, SD; Nakamura, YC; Parker, W; Platt, JL1
Griffith, LS; Rex-Mathes, M; Schmitz, B; Strutas, D; Thelen, K; Viebahn, C; Werner, S1
Dini, L; Mattioli, P1
Carter, TH; Zelinsky-Papez, K; Zimmerman, JA1
Gabrion, J; Loyzaga, PG; Uziel, A1

Reviews

2 review(s) available for acetylglucosamine and Aging

ArticleYear
O-GlcNAcylation in health and neurodegenerative diseases.
    Experimental & molecular medicine, 2021, Volume: 53, Issue:11

    Topics: Acetylglucosamine; Aging; Animals; Biomarkers; Brain; Diagnosis, Differential; Disease Susceptibility; Gene Expression Regulation; Glycosylation; Homeostasis; Humans; Neurodegenerative Diseases; Neurons; Protein Processing, Post-Translational

2021
Roles of O-GlcNAc in chronic diseases of aging.
    Molecular aspects of medicine, 2016, Volume: 51

    Topics: Acetylglucosamine; Aging; Chronic Disease; Diabetes Mellitus; Heart Diseases; Humans; Hyperglycemia; Inflammation; N-Acetylglucosaminyltransferases; Neoplasms; Neurodegenerative Diseases

2016

Trials

1 trial(s) available for acetylglucosamine and Aging

ArticleYear
Measurement of hyaluronidase activity in normal human serum.
    Journal of pharmaceutical and biomedical analysis, 1996, Volume: 14, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetylglucosamine; Adult; Aged; Aged, 80 and over; Aging; Borates; Colorimetry; Evaluation Studies as Topic; Female; Humans; Hyaluronic Acid; Hyaluronoglucosaminidase; Hydrogen-Ion Concentration; Indicators and Reagents; Male; Middle Aged; Sex Characteristics

1996

Other Studies

24 other study(ies) available for acetylglucosamine and Aging

ArticleYear
Regulation of the urea cycle by CPS1 O-GlcNAcylation in response to dietary restriction and aging.
    Journal of molecular cell biology, 2022, 07-05, Volume: 14, Issue:3

    Topics: Acetylglucosamine; Aging; Animals; Glycosylation; Liver; Mice; Protein Processing, Post-Translational; Urea

2022
Age-associated impairment of T cell immunity is linked to sex-dimorphic elevation of N-glycan branching.
    Nature aging, 2022, Volume: 2, Issue:3

    Topics: Acetylglucosamine; Aging; Animals; CD8-Positive T-Lymphocytes; Female; Humans; Interleukin-7; Male; Mice; Polysaccharides

2022
Neuronal O-GlcNAcylation Improves Cognitive Function in the Aged Mouse Brain.
    Current biology : CB, 2019, 10-21, Volume: 29, Issue:20

    Topics: Acetylglucosamine; Acylation; Aging; Animals; Cognition; Male; Mice; Mice, Knockout; N-Acetylglucosaminyltransferases

2019
Loss of CRMP2 O-GlcNAcylation leads to reduced novel object recognition performance in mice.
    Open biology, 2019, 11-29, Volume: 9, Issue:11

    Topics: Acetylglucosamine; Aging; Amino Acid Sequence; Animals; Cell Line; Cognition; Exploratory Behavior; Female; Gene Knock-In Techniques; Humans; Intercellular Signaling Peptides and Proteins; Male; Memory Disorders; Memory, Short-Term; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Point Mutation; Protein Processing, Post-Translational

2019
Spatiotemporal gating of SIRT1 functions by O-GlcNAcylation is essential for liver metabolic switching and prevents hyperglycemia.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 03-24, Volume: 117, Issue:12

    Topics: Acetylglucosamine; Aging; Animals; Fasting; Gluconeogenesis; Glycosylation; HEK293 Cells; Homeostasis; Humans; Hyperglycemia; Insulin Resistance; Liver; Male; Mice; Mice, Inbred C57BL; Obesity; Phosphorylation; Protein Processing, Post-Translational; Sirtuin 1; Spatio-Temporal Analysis

2020
Ogt controls neural stem/progenitor cell pool and adult neurogenesis through modulating Notch signaling.
    Cell reports, 2021, 03-30, Volume: 34, Issue:13

    Topics: Acetylglucosamine; Aging; Animals; Biocatalysis; Cell Differentiation; Cell Proliferation; Gene Deletion; Glycosylation; HEK293 Cells; Humans; Memory; Mice, Transgenic; N-Acetylglucosaminyltransferases; Neurogenesis; Proteolysis; Receptors, Notch; Signal Transduction; Stem Cells; Ubiquitin-Protein Ligases; Ubiquitination

2021
Profiling and genetic control of the murine immunoglobulin G glycome.
    Nature chemical biology, 2018, Volume: 14, Issue:5

    Topics: Acetylglucosamine; Aging; Animals; Fucose; Gene Expression Regulation; Genetic Variation; Glycopeptides; Glycosylation; Humans; Immunoglobulin G; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Peptides; Phenotype; Polysaccharides; Quantitative Trait Loci

2018
Aging Is Associated With Impaired Activation of Protein Homeostasis-Related Pathways After Cardiac Arrest in Mice.
    Journal of the American Heart Association, 2018, 09-04, Volume: 7, Issue:17

    Topics: Acetylglucosamine; Aging; Animals; Brain; Cardiopulmonary Resuscitation; Heart Arrest; Kidney; Mice; Proteostasis; Recovery of Function; Small Ubiquitin-Related Modifier Proteins; Spinal Cord; Ubiquitination; Unfolded Protein Response

2018
Retinal O-linked N-acetylglucosamine protein modifications: implications for postnatal retinal vascularization and the pathogenesis of diabetic retinopathy.
    Molecular vision, 2013, Volume: 19

    Topics: Acetylglucosamine; Aging; Animals; Animals, Newborn; Cell Movement; Diabetic Retinopathy; Eye Proteins; Glucose; Glycosylation; Insulin; Male; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; Pericytes; Protein Processing, Post-Translational; Retina; Retinal Vessels

2013
O-linked β-N-acetylglucosamine modification of proteins is activated in post-ischemic brains of young but not aged mice: Implications for impaired functional recovery from ischemic stress.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2016, Volume: 36, Issue:2

    Topics: Acetylglucosamine; Aging; Animals; Brain; Brain Ischemia; Male; Mice; Mice, Inbred C57BL; Myocardial Ischemia; Protein Processing, Post-Translational; Psychomotor Performance; Recovery of Function; Stress, Physiological; Stroke; SUMO-1 Protein; Ubiquitination; Unfolded Protein Response

2016
Disruption of O-linked N-Acetylglucosamine Signaling Induces ER Stress and β Cell Failure.
    Cell reports, 2015, Dec-22, Volume: 13, Issue:11

    Topics: Acetylglucosamine; Aging; Animals; Apoptosis; Cell Proliferation; Down-Regulation; Endoplasmic Reticulum Stress; Female; Glucose Tolerance Test; Hyperglycemia; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Acetylglucosaminyltransferases; Proto-Oncogene Proteins c-akt; Signal Transduction; Transcription Factor CHOP

2015
Anti-aging treatments slow propagation of synucleinopathy by restoring lysosomal function.
    Autophagy, 2016, 10-02, Volume: 12, Issue:10

    Topics: Acetylglucosamine; Aging; alpha-Synuclein; Animals; Caenorhabditis elegans; Disease Models, Animal; Endosomes; Humans; Lysosomes; Mutation; Polyubiquitin; Protein Aggregates; Transgenes; Ubiquitination

2016
O-GlcNAc and aging: C. elegans as a genetic model to test O-GlcNAc roles in type II diabetic insulin resistance.
    Aging, 2010, Volume: 2, Issue:11

    Topics: Acetylglucosamine; Aging; Animals; Caenorhabditis elegans; Diabetes Mellitus, Type 2; Insulin; Insulin Resistance; N-Acetylglucosaminyltransferases; Protein Processing, Post-Translational; Signal Transduction

2010
Pleiotropic and age-dependent effects of decreased protein modification by O-linked N-acetylglucosamine on pancreatic β-cell function and vascularization.
    The Journal of biological chemistry, 2011, Jul-22, Volume: 286, Issue:29

    Topics: Acetylglucosamine; Aging; Animals; beta-N-Acetylhexosaminidases; Female; Genetic Pleiotropy; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Mice; Mice, Transgenic; Neovascularization, Physiologic; Oxygen; Promoter Regions, Genetic; Protein Processing, Post-Translational; Rats; RNA, Messenger; Signal Transduction; Time Factors

2011
Human serum N-glycan profiles are age and sex dependent.
    Age and ageing, 2011, Volume: 40, Issue:5

    Topics: Acetylglucosamine; Adult; Age Distribution; Age Factors; Aging; Biomarkers; China; Electrophoresis; Female; Fucose; Glycomics; Glycosylation; Humans; Male; Middle Aged; Polysaccharides; Protein Processing, Post-Translational; Sex Distribution; Sex Factors

2011
Impact of Type 2 diabetes and aging on cardiomyocyte function and O-linked N-acetylglucosamine levels in the heart.
    American journal of physiology. Cell physiology, 2007, Volume: 292, Issue:4

    Topics: Acetylglucosamine; Aging; Animals; Biomechanical Phenomena; Calcium; Diabetes Mellitus, Type 2; Glycosylation; Hyperglycemia; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Myocytes, Cardiac; N-Acetylglucosaminyltransferases; Rats; Rats, Sprague-Dawley; Rats, Zucker

2007
Hexosamine biosynthetic pathway flux and cardiomyopathy in type 2 diabetes mellitus. Focus on "Impact of type 2 diabetes and aging on cardiomyocyte function and O-linked N-acetylglucosamine levels in the heart".
    American journal of physiology. Cell physiology, 2007, Volume: 292, Issue:4

    Topics: Acetylglucosamine; Aging; Animals; Biomechanical Phenomena; Calcium; Cardiomyopathies; Diabetes Mellitus, Type 2; Glycosylation; Hexosamines; Hyperglycemia; Myocardial Contraction; Myocardium; Myocytes, Cardiac; N-Acetylglucosaminyltransferases; Rats

2007
Aging leads to increased levels of protein O-linked N-acetylglucosamine in heart, aorta, brain and skeletal muscle in Brown-Norway rats.
    Biogerontology, 2008, Volume: 9, Issue:3

    Topics: Acetylglucosamine; Aging; Animals; Aorta; Base Sequence; Brain; Chromatography, High Pressure Liquid; DNA Primers; Male; Muscle, Skeletal; Myocardium; Proteins; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2008
Development of interglobular dentine in rat molars and its relation to maturation of enamel.
    Anatomy and embryology, 1997, Volume: 196, Issue:6

    Topics: Acetylglucosamine; Aging; Ameloblasts; Animals; Animals, Newborn; Dental Enamel; Dentin; Histocytochemistry; Male; Microscopy, Fluorescence; Molar; Rats; Rats, Wistar

1997
Natural anti-carbohydrate IgM in mice: dependence on age and strain.
    Journal of immunological methods, 2000, Dec-01, Volume: 246, Issue:1-2

    Topics: Acetylglucosamine; Aging; Animals; Enzyme-Linked Immunosorbent Assay; Immunoglobulin M; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Species Specificity

2000
O-GlcNAc expression in developing and ageing mouse brain.
    Biochimie, 2001, Volume: 83, Issue:7

    Topics: Acetylgalactosamine; Acetylglucosamine; Aging; Animals; Antibodies, Monoclonal; Blotting, Western; Brain; Cells, Cultured; Cerebellum; Embryo, Mammalian; Enzyme Inhibitors; Fluorescent Antibody Technique, Direct; Gene Expression; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Neurons; Oximes; Phenylcarbamates; Protein Binding; Substrate Specificity

2001
Carbohydrate recognition systems in avian sinusoidal liver cells.
    Bioscience reports, 1990, Volume: 10, Issue:1

    Topics: Acetylglucosamine; Aging; Animals; Carbohydrate Metabolism; Chick Embryo; Chickens; Female; Galactose; Glycoproteins; Histocytochemistry; Lectins, C-Type; Liver; Male; Mannose; Mannose Receptor; Mannose-Binding Lectins; Perfusion; Receptors, Cell Surface; Receptors, Immunologic; Receptors, N-Acetylglucosamine

1990
Isolation and characterization of chemically transformed pancreatic acinar cell lines from young and old mice.
    In vitro cellular & developmental biology : journal of the Tissue Culture Association, 1987, Volume: 23, Issue:2

    Topics: Acetylglucosamine; Aging; Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Isoenzymes; Karyotyping; L-Lactate Dehydrogenase; Lectins; Male; Methylnitrosourea; Mice; Pancreatic Neoplasms; Phenotype; Plant Lectins; Soybean Proteins; Tetradecanoylphorbol Acetate

1987
Lectins demonstrate the presence of carbohydrates in the tectorial membrane of mammalian cochlea.
    Hearing research, 1985, Volume: 20, Issue:1

    Topics: Acetylglucosamine; Aging; Animals; Animals, Newborn; Autoradiography; Carbohydrates; Cochlea; Fluorescent Antibody Technique; Fucose; Galactose; Guinea Pigs; Lectins; Mannose; Rats; Tectorial Membrane

1985