acetylcysteine and Substance Withdrawal Syndrome

acetylcysteine has been researched along with Substance Withdrawal Syndrome in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (22.22)29.6817
2010's12 (66.67)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Cano-Cebrián, MJ; Fernández-Rodríguez, S; Granero, L; Hipólito, L; Polache, A; Zornoza, T1
Goudriaan, AE; Kaag, AM; Kooi, DP; Schmaal, L; Schulte, M; van den Brink, W; Wiers, RW1
Cox, S; Dawkins, L; Doig, M; Goniewicz, M; Kimber, C; Kośmider, L; McRobbie, H1
al'Absi, M; Allen, SS; Benowitz, NL; Carmella, SG; Chen, M; Cinciripini, PM; Denlinger-Apte, R; Donny, EC; Drobes, DJ; Hatsukami, DK; Hecht, SS; Jensen, JA; Koopmeiners, JS; Lane, T; Le, CT; Leischow, S; Luo, K; Luo, X; McClernon, FJ; Murphy, SE; Paiano, V; Robinson, JD; Severson, H; Sipe, C; Strasser, AA; Strayer, LG; Tang, MK; Vandrey, R1
Bimonte-Nelson, HA; Gipson, CD; Goenaga, J; Koebele, SV; Leyrer-Jackson, JM; McClure, EA; Namba, MD; Phan, S; Piña, J; Powell, GL; Prakapenka, AV1
da Rosa Araujo, AS; Herrmann, AP; Marcon, M; Mocelin, R; Piato, A1
Gipson, CD; Gray, KM; Kalivas, PW; Malcolm, RJ; McClure, EA1
Karimian Sichani, N; Maracy, M; Mousavi, SG; Peykanpour, M; Salehi, M; Sharbafchi, MR1
Clarimundo, V; Dalmaz, C; Elisabetsky, E; Gomez, R; Santos, CF; Schneider, R1
Froeliger, B; Gray, KM; Kalivas, PW; McClure, EA; McConnell, PA; Stankeviciute, N1
Bowers, MS; Damaj, MI; Jackson, A; Maldoon, PP1
Baker, NL; Cloud, K; Gray, KM; Killeen, TK; McRae-Clark, AL; Sherman, BJ; Sonne, SC1
Hedden, S; Kalivas, PW; Knackstedt, LA; LaRowe, S; Malcolm, R; Mardikian, P; Markou, A; Upadhyaya, H1
Gass, JT; Kalivas, PW; Lavin, A; Moran, M; Moussawi, K; Olive, MF; Pacchioni, A1
Do, PH; Kalivas, PW; Moussawi, K; Reichel, CM; See, RE1
Baker, NL; Gray, KM; Roten, AT1
Baker, DA; Kalivas, PW; Lake, RW; McFarland, K; Shen, H; Tang, XC; Toda, S1
Downey, HF; Jung, ME; Mallet, RT; Simpkins, JW; Wilson, AM1

Reviews

1 review(s) available for acetylcysteine and Substance Withdrawal Syndrome

ArticleYear
Potential role of N-acetylcysteine in the management of substance use disorders.
    CNS drugs, 2014, Volume: 28, Issue:2

    Topics: Acetylcysteine; Animals; Clinical Trials as Topic; Drug Evaluation, Preclinical; Humans; Molecular Structure; Substance Withdrawal Syndrome; Substance-Related Disorders; Treatment Outcome

2014

Trials

7 trial(s) available for acetylcysteine and Substance Withdrawal Syndrome

ArticleYear
The effect of N-acetylcysteine on brain glutamate and gamma-aminobutyric acid concentrations and on smoking cessation: A randomized, double-blind, placebo-controlled trial.
    Journal of psychopharmacology (Oxford, England), 2017, Volume: 31, Issue:10

    Topics: Acetylcysteine; Adult; Craving; Double-Blind Method; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; Humans; Male; Smoking Cessation; Substance Withdrawal Syndrome; Tobacco Use Disorder

2017
Effect of Immediate vs Gradual Reduction in Nicotine Content of Cigarettes on Biomarkers of Smoke Exposure: A Randomized Clinical Trial.
    JAMA, 2018, 09-04, Volume: 320, Issue:9

    Topics: Acetylcysteine; Adult; Area Under Curve; Biomarkers; Breath Tests; Carbon Monoxide; Creatinine; Double-Blind Method; Female; Humans; Male; Middle Aged; Nicotiana; Nicotine; Phenanthrenes; Smoke; Smoking Cessation; Substance Withdrawal Syndrome; Tobacco Products; Tobacco Use Disorder

2018
The efficacy of N-acetylcysteine in the treatment of methamphetamine dependence: a double-blind controlled, crossover study.
    Archives of Iranian medicine, 2015, Volume: 18, Issue:1

    Topics: Acetylcysteine; Adult; Amphetamine-Related Disorders; Central Nervous System Stimulants; Craving; Cross-Over Studies; Double-Blind Method; Female; Free Radical Scavengers; Humans; Male; Methamphetamine; Substance Withdrawal Syndrome; Surveys and Questionnaires; Treatment Outcome; Young Adult

2015
The effects of N-Acetylcysteine on frontostriatal resting-state functional connectivity, withdrawal symptoms and smoking abstinence: A double-blind, placebo-controlled fMRI pilot study.
    Drug and alcohol dependence, 2015, Nov-01, Volume: 156

    Topics: Acetylcysteine; Adult; Corpus Striatum; Double-Blind Method; Female; Frontal Lobe; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neural Pathways; Pilot Projects; Smoking Cessation; Substance Withdrawal Syndrome; Tobacco Use Disorder

2015
Gender differences among treatment-seeking adults with cannabis use disorder: Clinical profiles of women and men enrolled in the achieving cannabis cessation-evaluating N-acetylcysteine treatment (ACCENT) study.
    The American journal on addictions, 2017, Volume: 26, Issue:2

    Topics: Acetylcysteine; Adult; Cannabinoids; Comorbidity; Female; Free Radical Scavengers; Help-Seeking Behavior; Humans; Male; Marijuana Abuse; Mental Disorders; Middle Aged; Patient Acceptance of Health Care; Patient Care Management; Sex Factors; Substance Withdrawal Syndrome

2017
The role of cystine-glutamate exchange in nicotine dependence in rats and humans.
    Biological psychiatry, 2009, May-15, Volume: 65, Issue:10

    Topics: Acetylcysteine; Amino Acid Transport System y+; Amygdala; Animals; Brain; Carbon Monoxide; Excitatory Amino Acid Transporter 2; Female; Humans; Male; Middle Aged; Nicotine; Nucleus Accumbens; Pilot Projects; Prefrontal Cortex; Rats; Rats, Wistar; Self Administration; Substance Withdrawal Syndrome; Tobacco Use Disorder; Ventral Tegmental Area

2009
Marijuana craving trajectories in an adolescent marijuana cessation pharmacotherapy trial.
    Addictive behaviors, 2013, Volume: 38, Issue:3

    Topics: Acetylcysteine; Adolescent; Combined Modality Therapy; Counseling; Drug Administration Schedule; Excitatory Amino Acid Agonists; Female; Humans; Male; Marijuana Abuse; Self Report; Substance Withdrawal Syndrome; Young Adult

2013

Other Studies

10 other study(ies) available for acetylcysteine and Substance Withdrawal Syndrome

ArticleYear
Efficacy of N-acetylcysteine in the prevention of alcohol relapse-like drinking: Study in long-term ethanol-experienced male rats.
    Journal of neuroscience research, 2021, Volume: 99, Issue:2

    Topics: Acetylcysteine; Alcohol Drinking; Alcoholism; Animals; Drug Evaluation, Preclinical; Ethanol; Infusions, Subcutaneous; Injections, Subcutaneous; Male; Models, Animal; Random Allocation; Rats; Rats, Wistar; Recurrence; Substance Withdrawal Syndrome

2021
'Real-world' compensatory behaviour with low nicotine concentration e-liquid: subjective effects and nicotine, acrolein and formaldehyde exposure.
    Addiction (Abingdon, England), 2018, Volume: 113, Issue:10

    Topics: Acetylcysteine; Acrolein; Adult; Cotinine; Craving; England; Female; Formaldehyde; Formates; Humans; Inhalation Exposure; Male; Middle Aged; Nicotine; Nicotinic Agonists; Saliva; Substance Withdrawal Syndrome; Vaping; Young Adult

2018
N-acetylcysteine yields sex-specific efficacy for cue-induced reinstatement of nicotine seeking.
    Addiction biology, 2020, Volume: 25, Issue:1

    Topics: Acetylcysteine; Animals; Craving; Cues; Disease Models, Animal; Drug-Seeking Behavior; Estrous Cycle; Extinction, Psychological; Female; Free Radical Scavengers; Male; Nicotine; Rats; Rats, Sprague-Dawley; Sex Factors; Substance Withdrawal Syndrome; Tobacco Use Disorder

2020
Withdrawal effects following repeated ethanol exposure are prevented by N-acetylcysteine in zebrafish.
    Progress in neuro-psychopharmacology & biological psychiatry, 2019, 07-13, Volume: 93

    Topics: Acetylcysteine; Animals; Anxiety; Brain; Catalase; Disease Models, Animal; Ethanol; Female; Lipid Peroxidation; Male; Oxidative Stress; Substance Withdrawal Syndrome; Superoxide Dismutase; Zebrafish

2019
N-acetylcysteine prevents behavioral and biochemical changes induced by alcohol cessation in rats.
    Alcohol (Fayetteville, N.Y.), 2015, Volume: 49, Issue:3

    Topics: Acetylcysteine; Animals; Anxiety; Behavior, Animal; Central Nervous System Depressants; Corticosterone; Ethanol; Free Radical Scavengers; Leptin; Motor Activity; Rats; Rats, Wistar; Substance Withdrawal Syndrome

2015
N-acetylcysteine decreased nicotine reward-like properties and withdrawal in mice.
    Psychopharmacology, 2016, Volume: 233, Issue:6

    Topics: Acetylcysteine; Animals; Association Learning; Dose-Response Relationship, Drug; Male; Mecamylamine; Mice; Mice, Inbred ICR; Nicotine; Reward; Substance Withdrawal Syndrome; Tobacco Use Disorder

2016
N-Acetylcysteine reverses cocaine-induced metaplasticity.
    Nature neuroscience, 2009, Volume: 12, Issue:2

    Topics: Acetylcysteine; Animals; Behavior, Animal; Cocaine-Related Disorders; Disease Models, Animal; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Free Radical Scavengers; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Neuronal Plasticity; Nucleus Accumbens; Prefrontal Cortex; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Secondary Prevention; Self Administration; Substance Withdrawal Syndrome

2009
Chronic N-acetylcysteine during abstinence or extinction after cocaine self-administration produces enduring reductions in drug seeking.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 337, Issue:2

    Topics: Acetylcysteine; Animals; Cocaine; Cocaine-Related Disorders; Cues; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Glutamic Acid; Homeostasis; Male; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Substance Withdrawal Syndrome

2011
Neuroadaptations in cystine-glutamate exchange underlie cocaine relapse.
    Nature neuroscience, 2003, Volume: 6, Issue:7

    Topics: Acetylcysteine; Adaptation, Physiological; Analysis of Variance; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corpus Striatum; Cystine; Dose-Response Relationship, Drug; Expectorants; Extinction, Psychological; Extracellular Space; Glutamic Acid; Male; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Recurrence; Reinforcement, Psychology; Self Administration; Substance Withdrawal Syndrome; Time Factors

2003
Intermittent hypoxia conditioning prevents behavioral deficit and brain oxidative stress in ethanol-withdrawn rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2008, Volume: 105, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Behavior, Animal; Brain Chemistry; Central Nervous System Depressants; Dextrins; Diet; Ethanol; Hypoxia; Ischemic Preconditioning; Male; Mitochondria; Mitochondrial Membranes; Mitochondrial Swelling; Oxidants; Oxidative Stress; Protein Carbonylation; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Superoxides

2008