acetylcysteine and Skin Neoplasms

acetylcysteine has been researched along with Skin Neoplasms in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.45)18.7374
1990's3 (10.34)18.2507
2000's12 (41.38)29.6817
2010's10 (34.48)24.3611
2020's3 (10.34)2.80

Authors

AuthorsStudies
Baetz, T; Flemming, JA; Grin, A; Motomura, D1
Asthana, S; Chaturvedi, S; Dewangan, J; Divakar, A; Kumar, S; Mishra, S; Rath, SK; Sharma, D; Srivastava, S; Wahajuddin, M1
Chang, SN; Choi, DK; Hwang, BS; Kang, SC; Khan, I; Kim, CG; Lee, H; Park, JG; Park, SM1
Ajith, TA; Antonawich, F; Janardhanan, KK; Veena, RK1
Chen, W; Li, X; Wu, J; Zhang, X1
Akaike, T; Aoi, J; Endo, M; Fukushima, S; Hirakawa, S; Horiguchi, H; Ihn, H; Jinnin, M; Kadomatsu, T; Masuda, T; Miyata, K; Odagiri, H; Ogata, A; Oike, Y; Sawa, T1
Bartozzi, B; Bernardini, G; Pierpaoli, E; Provinciali, M1
Soliman, E; Van Dross, R1
Boucher, KM; Cassidy, PB; Florell, SR; Grossman, D; Honeggar, M; Leachman, SA; Liu, T1
Hanausek, M; Kinjo, T; Kowalczyk, MC; Kowalczyk, P; Slaga, TJ; Walaszek, Z1
Boucher, KM; Cassidy, P; Cotter, MA; Florell, SR; Goodson, AG; Grossman, D; Liu, T; Wade, M1
Czyz, M; Düchler, M; Koprowska, K; Lesiak, K; Nejc, D; Zalesna, I1
Nickoloff, BJ; Qin, JZ; Xin, H1
Esser, PR; Lademann, J; Martin, SF; Schempp, CM; Simon-Haarhaus, B; Wölfle, U1
Han, CY; Hien, TT; Kang, KW; Lim, SC1
Barrett, JC; French, JE; Kari, FW; Martin, KR; Saulnier, MJ1
Chang, C; Chapman, PB; Fleisher, M; Hwu, WJ; Krown, SE; Livingston, PO; Pinto, JT; Williams, L; Wolchok, JD1
Cho, D; Hahm, E; Hur, D; Hwang, YI; Kang, JS; Kim, D; Kim, S; Kim, YI; Kim, YS; Lee, WJ; Pang, S; Park, H; Park, JH; Yang, Y1
Balansky, RM; Camoirano, A; D'Agostini, F; De Flora, S1
Bracci-Laudiero, L; Edlundh-Rose, E; Greco, G; Gustafsson, AC; Krasnowska, EK; Kupershmidt, I; Lundeberg, J; Lundeberg, T; Parasassi, T; Romano, MC; Serafino, A1
Ivanov, V; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW; Roomi, NW1
Slaga, TJ; Warren, BS1
Brash, DE; Liu, M; Wikonkal, NM1
Colburn, NH; Collins, K; Davis, MA; Flaws, JA; Young, M1
Bandrés, E; García-Foncillas, J; Okroujnov, I; Redondo, P; Solano, T1
Higashi, Y; Kanekura, T; Kanzaki, T1
Barrett, JC; French, JE; Kari, FW; Martin, KR; Saulnier, M; Trempus, C1
Brötell, H; Hallberg, A; Karg, E; Rorsman, H; Rosengren, E; Tunek, A1
Rotstein, JB; Slaga, TJ1

Reviews

1 review(s) available for acetylcysteine and Skin Neoplasms

ArticleYear
Mechanisms of inhibition of tumor progression.
    Basic life sciences, 1993, Volume: 61

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Benzoates; Benzoic Acid; Butylated Hydroxyanisole; Carcinogens; Carcinoma; Cell Division; Disulfiram; Glutathione; Glutathione Disulfide; Mice; Papilloma; Skin Neoplasms; Vitamin E

1993

Trials

2 trial(s) available for acetylcysteine and Skin Neoplasms

ArticleYear
A Phase II Randomized Placebo-Controlled Trial of Oral N-acetylcysteine for Protection of Melanocytic Nevi against UV-Induced Oxidative Stress In Vivo.
    Cancer prevention research (Philadelphia, Pa.), 2017, Volume: 10, Issue:1

    Topics: Acetylcysteine; Administration, Oral; Antioxidants; Biomarkers; Double-Blind Method; Glutamate-Cysteine Ligase; Guanine; Humans; Melanoma; Mutation; Nevus, Pigmented; Oxidative Stress; Pilot Projects; Receptor, Melanocortin, Type 1; Skin Neoplasms; Sunlight; Thioredoxin Reductase 1; Ultraviolet Rays

2017
Phase I trial of high dose paracetamol and carmustine in patients with metastatic melanoma.
    Melanoma research, 2003, Volume: 13, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antineoplastic Agents, Alkylating; Carmustine; Cohort Studies; Dose-Response Relationship, Drug; Female; Free Radical Scavengers; Glutathione; Glutathione Reductase; Humans; Leukocytes, Mononuclear; Liver Neoplasms; Lymphatic Metastasis; Male; Maximum Tolerated Dose; Melanoma; Neoplasm Metastasis; Skin Neoplasms; Time Factors

2003

Other Studies

26 other study(ies) available for acetylcysteine and Skin Neoplasms

ArticleYear
Severe Refractory Checkpoint Inhibitor-Related Hepatitis Reversed With Anti-Thymocyte Globulin and n-Acetylcysteine.
    Hepatology (Baltimore, Md.), 2020, Volume: 72, Issue:6

    Topics: Acetylcysteine; Antilymphocyte Serum; Chemotherapy, Adjuvant; Drug Resistance; Drug Therapy, Combination; Female; Glucocorticoids; Hepatitis; Humans; Immune Checkpoint Inhibitors; Immunosuppressive Agents; Melanoma; Middle Aged; Severity of Illness Index; Skin Neoplasms; Treatment Outcome

2020
N-acetyl-cysteine in combination with celecoxib inhibits Deoxynivalenol induced skin tumor initiation via induction of autophagic pathways in swiss mice.
    Free radical biology & medicine, 2020, 08-20, Volume: 156

    Topics: Acetylcysteine; Animals; Autophagy; Celecoxib; Mice; Skin Neoplasms; Trichothecenes

2020
Decursinol Angelate Arrest Melanoma Cell Proliferation by Initiating Cell Death and Tumor Shrinkage via Induction of Apoptosis.
    International journal of molecular sciences, 2021, Apr-15, Volume: 22, Issue:8

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Apoptosis; Autophagosomes; Benzopyrans; Butyrates; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Humans; Male; Melanoma; Melanoma, Experimental; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Mitochondrial Membranes; Models, Biological; Reactive Oxygen Species; Skin Neoplasms

2021
Poly-MVA attenuates 7,12- dimethylbenz[a]anthracene initiated and croton oil promoted skin papilloma formation on mice skin.
    Journal of experimental therapeutics & oncology, 2017, Volume: 11, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetylcysteine; Animals; Carcinogens; Croton Oil; Dietary Supplements; Female; Free Radical Scavengers; Inflammation; Lipid Peroxidation; Mice; Molybdenum; N-Formylmethionine; Palladium; Papilloma; Rhodium; Ruthenium; Skin Neoplasms; Thioctic Acid; Vitamin B Complex

2017
Glutathione reductase-mediated thiol oxidative stress suppresses metastasis of murine melanoma cells.
    Free radical biology & medicine, 2018, Volume: 129

    Topics: Acetylcysteine; Actins; Animals; Antineoplastic Agents; Cadherins; Carcinogenesis; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Glutathione Reductase; Isografts; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Skin Neoplasms; Snail Family Transcription Factors; Thiocarbamates; Tumor Burden; Vimentin

2018
Angiopoietin-like protein 2 accelerates carcinogenesis by activating chronic inflammation and oxidative stress.
    Molecular cancer research : MCR, 2014, Volume: 12, Issue:2

    Topics: Acetylcysteine; Angiopoietins; Animals; Carcinoma, Squamous Cell; DNA Methylation; Gene Expression Regulation, Neoplastic; Inflammation; Male; Mice; Mice, Knockout; MutS Homolog 2 Protein; Neoplasms, Experimental; Oxidative Stress; Promoter Regions, Genetic; Skin Neoplasms

2014
Zinc Induces Apoptosis of Human Melanoma Cells, Increasing Reactive Oxygen Species, p53 and FAS Ligand.
    Anticancer research, 2015, Volume: 35, Issue:10

    Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Fas Ligand Protein; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Reactive Oxygen Species; Skin Neoplasms; Tumor Suppressor Protein p53; Zinc

2015
Anandamide-induced endoplasmic reticulum stress and apoptosis are mediated by oxidative stress in non-melanoma skin cancer: Receptor-independent endocannabinoid signaling.
    Molecular carcinogenesis, 2016, Volume: 55, Issue:11

    Topics: Acetylcysteine; Animals; Apoptosis; Arachidonic Acids; Cell Line, Tumor; Cell Survival; Chromans; Endocannabinoids; Endoplasmic Reticulum Stress; Gene Expression Regulation, Neoplastic; Humans; Mice; Oxidative Stress; Polyunsaturated Alkamides; Receptors, Cannabinoid; Signal Transduction; Skin Neoplasms

2016
Differential effects of several phytochemicals and their derivatives on murine keratinocytes in vitro and in vivo: implications for skin cancer prevention.
    Carcinogenesis, 2009, Volume: 30, Issue:6

    Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Aryl Hydrocarbon Hydroxylases; Carotenoids; Cell Line; Cell Line, Tumor; Cell Transformation, Neoplastic; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Ellagic Acid; Female; Free Radical Scavengers; Free Radicals; Genes, ras; Keratinocytes; Lycopene; Mice; Mutation; Plant Extracts; Proto-Oncogene Proteins p21(ras); Resveratrol; Skin Neoplasms; Stilbenes; Triterpenes; Ursolic Acid; Vitis

2009
Use of oral N-acetylcysteine for protection of melanocytic nevi against UV-induced oxidative stress: towards a novel paradigm for melanoma chemoprevention.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Dec-01, Volume: 15, Issue:23

    Topics: Acetylcysteine; Administration, Oral; Adult; Aged; Anticarcinogenic Agents; Antioxidants; Cysteine; Female; Glutathione; Humans; Male; Melanoma; Middle Aged; Nevus, Pigmented; Oxidative Stress; Risk; Skin Neoplasms; Time Factors; Ultraviolet Rays

2009
Parthenolide, a sesquiterpene lactone from the medical herb feverfew, shows anticancer activity against human melanoma cells in vitro.
    Melanoma research, 2010, Volume: 20, Issue:1

    Topics: Acetylcysteine; Adult; Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Adhesion; Cell Growth Processes; Cell Line, Tumor; Drug Interactions; Female; Flow Cytometry; Humans; Male; Melanoma; Membrane Potential, Mitochondrial; Mice; Middle Aged; Reactive Oxygen Species; Sesquiterpenes; Skin Neoplasms; Tanacetum parthenium

2010
3-Bromopyruvate induces necrotic cell death in sensitive melanoma cell lines.
    Biochemical and biophysical research communications, 2010, May-28, Volume: 396, Issue:2

    Topics: Acetylcysteine; Adenosine Triphosphate; Apoptosis; Cell Line, Tumor; Glutathione; Humans; Melanoma; Membrane Potential, Mitochondrial; Necrosis; Pyruvates; Skin Neoplasms; Superoxides

2010
UVB-induced DNA damage, generation of reactive oxygen species, and inflammation are effectively attenuated by the flavonoid luteolin in vitro and in vivo.
    Free radical biology & medicine, 2011, May-01, Volume: 50, Issue:9

    Topics: Acetylcysteine; Antioxidants; Cell Line; Chromans; Cyclooxygenase 2; Cytoprotection; Dinoprostone; DNA Damage; Erythema; Extracellular Signal-Regulated MAP Kinases; Fluoresceins; Gene Expression; Humans; Inflammation; Inhibitory Concentration 50; Keratinocytes; Luteolin; Organ Culture Techniques; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pyrimidine Dimers; Reactive Oxygen Species; Skin; Skin Neoplasms; Ultraviolet Rays

2011
Role of Pin1 in UVA-induced cell proliferation and malignant transformation in epidermal cells.
    Biochemical and biophysical research communications, 2011, Jun-24, Volume: 410, Issue:1

    Topics: Acetylcysteine; Animals; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin D1; Epidermis; Humans; Mice; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Reactive Oxygen Species; Skin Neoplasms; Transcription Factor AP-1; Ultraviolet Rays

2011
Timing of supplementation with the antioxidant N-acetyl-L-cysteine reduces tumor multiplicity in novel, cancer-prone p53 haploinsufficient Tg.AC (v-Ha-ras) transgenic mice but has no impact on malignant progression.
    Nutrition and cancer, 2002, Volume: 43, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cross-Over Studies; Dietary Supplements; Disease Models, Animal; Female; Free Radical Scavengers; Genes, ras; Linear Models; Male; Mice; Mice, Transgenic; Sarcoma; Skin Neoplasms; Survival Rate; Time Factors

2002
Vitamin C downregulates interleukin-18 production by increasing reactive oxygen intermediate and mitogen-activated protein kinase signalling in B16F10 murine melanoma cells.
    Melanoma research, 2003, Volume: 13, Issue:6

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Blotting, Western; Cell Line, Tumor; Densitometry; Down-Regulation; Enzyme Inhibitors; Flow Cytometry; Imidazoles; Immunoprecipitation; Interleukin-18; MAP Kinase Signaling System; Melanoma; Mice; p38 Mitogen-Activated Protein Kinases; Pyridines; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Skin Neoplasms; Time Factors

2003
Modulation of light-induced skin tumors by N-acetylcysteine and/or ascorbic acid in hairless mice.
    Carcinogenesis, 2005, Volume: 26, Issue:3

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Female; Mice; Mice, Hairless; Skin Neoplasms; Ultraviolet Rays

2005
Global gene expression analysis in time series following N-acetyl L-cysteine induced epithelial differentiation of human normal and cancer cells in vitro.
    BMC cancer, 2005, Jul-07, Volume: 5

    Topics: Acetylcysteine; Antioxidants; Cadherins; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Lineage; Cell Proliferation; Cytoskeleton; Down-Regulation; Epithelium; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genome, Human; Humans; Keratinocytes; Kinetics; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Skin Neoplasms; Time Factors; Transcription, Genetic; Up-Regulation

2005
Inhibition of 7,12-dimethylbenzanthracene-induced skin tumors by a nutrient mixture.
    Medical oncology (Northwood, London, England), 2008, Volume: 25, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetylcysteine; Amino Acids; Animals; Arginine; Ascorbic Acid; Camellia sinensis; Carcinogens; Copper; Diet; Female; Keratoacanthoma; Lysine; Manganese; Mice; Mice, Inbred SENCAR; Papilloma; Plant Extracts; Proline; Selenium; Skin; Skin Neoplasms

2008
Induction of cyclin-dependent kinase inhibitors and G(1) prolongation by the chemopreventive agent N-acetylcysteine.
    Carcinogenesis, 1999, Volume: 20, Issue:9

    Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Antioxidants; Cell Cycle; Cell Line; Chromans; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Fibroblasts; Free Radical Scavengers; G1 Phase; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, p16; Glutathione; Humans; Keratinocytes; Mice; Models, Biological; Neoplasm Proteins; Papilloma; Skin Neoplasms; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1999
Effect of ceramide on intracellular glutathione determines apoptotic or necrotic cell death of JB6 tumor cells.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 53, Issue:1

    Topics: Acetylcysteine; Animals; Apoptosis; Drug Resistance; Glutathione; Mice; Necrosis; Propidium; Reactive Oxygen Species; Skin Neoplasms; Sphingosine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2000
Vascular endothelial growth factor (VEGF) and melanoma. N-acetylcysteine downregulates VEGF production in vitro.
    Cytokine, 2000, Volume: 12, Issue:4

    Topics: Acetylcysteine; Adult; Antioxidants; Cells, Cultured; Down-Regulation; Endothelial Growth Factors; Female; Humans; Lymphokines; Male; Melanocytes; Melanoma; Middle Aged; Neoplasm Recurrence, Local; Skin Neoplasms; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2000
Inhibitory effects of 9-cis-retinoic acid and pyrrolidinedithiocarbamate on cyclooxygenase (COX)-2 expression and cell growth in human skin squamous carcinoma cells.
    Cancer letters, 2000, Dec-20, Volume: 161, Issue:2

    Topics: Acetylcysteine; Alitretinoin; Antineoplastic Agents; Antioxidants; Blotting, Western; Carcinoma, Squamous Cell; Cell Division; Cell Line; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Free Radical Scavengers; Humans; Isoenzymes; Keratinocytes; Membrane Proteins; Oligonucleotides, Antisense; Prostaglandin-Endoperoxide Synthases; Pyrrolidines; Retinoids; Skin Neoplasms; Thiocarbamates; Time Factors; Transfection; Tretinoin; Tumor Cells, Cultured

2000
Dietary N-acetyl-L-cysteine modulates benzo[a]pyrene-induced skin tumors in cancer-prone p53 haploinsufficient Tg.AC (v-Ha-ras) mice.
    Carcinogenesis, 2001, Volume: 22, Issue:9

    Topics: Acetylcysteine; Animals; Antioxidants; Benzo(a)pyrene; Carcinogens; Carcinoma, Squamous Cell; Cocarcinogenesis; Crosses, Genetic; Dietary Supplements; Female; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; Genes, p53; Genes, ras; Genetic Predisposition to Disease; Haplotypes; Male; Mice; Mice, Transgenic; Skin Neoplasms; Transgenes; Tumor Suppressor Protein p53

2001
Glutathione in human melanoma cells. Effects of cysteine, cysteine esters and glutathione isopropyl ester.
    Journal of dermatological science, 1990, Volume: 1, Issue:1

    Topics: Acetylcysteine; Cysteine; Expectorants; Glutathione; Humans; Melanoma; Skin Neoplasms; Tumor Cells, Cultured

1990
Effect of exogenous glutathione on tumor progression in the murine skin multistage carcinogenesis model.
    Carcinogenesis, 1988, Volume: 9, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetylcysteine; Animals; Antioxidants; Carcinoma; Disulfiram; Free Radicals; Glutathione; Mice; Oxidation-Reduction; Papilloma; Precancerous Conditions; Skin Neoplasms

1988