acetylcysteine and Shock, Septic

acetylcysteine has been researched along with Shock, Septic in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (31.03)18.2507
2000's18 (62.07)29.6817
2010's2 (6.90)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Buckley, M; Krakauer, T1
Batteux, F; Benhamou, D; Borderie, D; Cherreau, C; Conti, M; Dupic, L; Duranteau, J; Huet, O; Mira, JP; Nicco, C; Pene, F; Vicaut, E1
Ellouze, O; Frikha, N; Mestiri, T; Ouerghi, S; Salah Ben Ammar, M1
Lenschat, A; Morrison, DC; Perera, PY; Qureshi, N; Shen, J; Splitter, G; Vogel, SN; Zhang, G1
Del Sorbo, L; Zhang, H1
Armstrong, VW; Hein, OV; Kox, WJ; Oellerich, M; Ohring, R; Schilling, A; Spies, C1
Asfar, P; De Backer, D; Meier-Hellmann, A; Radermacher, P; Sakka, SG1
Spapen, H1
Huang, XL; Ling, YL; Ling, YQ; Zhang, JL; Zhu, TN1
Kolbert, C; Morrison, DC; Papasian, C; Qureshi, AA; Qureshi, N; Raghavakaimal, S; Reis, J; Shen, J; Vogel, SN1
Chen, HI; Harn, HJ; Hsu, BG; Lee, RP; Yang, FL1
Banks, S; Costello, R; Csako, G; Danner, RL; Eichacker, P; Esposito, C; Kalil, AC; Myers, DE; Natanson, C; Sevransky, JE; Sittler, KJ; Solomon, SB; Susla, GM; Vandivier, RW1
Bakker, J; Nguyen, DN; Rogiers, P; Spapen, H; Vincent, JL; Zhang, H1
Bakker, J; Depierreux, M; van Asbeck, S; Vincent, JL; Zhang, H1
Bredle, DL; Hannemann, L; Meier-Hellmann, A; Reinhart, K; Schaffartzik, W; Spies, CD; Witt, I1
Leppard, PI; Moran, JL; Peake, SL1
Galley, HF; Howdle, PD; Walker, BE; Webster, NR1
Demanet, C; Huyghens, L; Spapen, H; Vincent, JL; Vleminckx, W; Zhang, H1
Caputi, AP; Costantino, G; Cuzzocrea, S; Mazzon, E1
De la Fuente, M; Del Río, M; Garrote, D; Guayerbas, N; Víctor, VM1
De la Fuente, M; Victor, VM2
Fan, J; Kapus, A; Li, YH; Marshall, JC; Rizoli, S; Rotstein, OD1
Cantini, Q; Conti, A; De Gaudio, AR; Moraldi, E; Novelli, G; Ortolani, O1
Haertel, C; Lenhart, A; Meier-Hellmann, A; Michel, C; Rank, N; Spies, C; Welte, M1
Kiefer, P; Radermacher, P; Vogt, J1
Breitkreutz, R; Groth, G; Heller, AR; Heller, SC; Koch, T; Nebe, T; Quintel, M1
Ahola, T; Lapatto, R1
Conti, A; De Gaudio, AR; Moraldi, E; Novelli, GP; Ortolani, O1

Reviews

4 review(s) available for acetylcysteine and Shock, Septic

ArticleYear
[N-acetylcysteine in septic shock].
    La Tunisie medicale, 2011, Volume: 89, Issue:10

    Topics: Acetylcysteine; Free Radical Scavengers; Humans; Shock, Septic

2011
Clinical review: influence of vasoactive and other therapies on intestinal and hepatic circulations in patients with septic shock.
    Critical care (London, England), 2004, Volume: 8, Issue:3

    Topics: Acetylcysteine; Fluid Therapy; Hemodynamics; Humans; Intestinal Mucosa; Liver; Multiple Organ Failure; Oxygen; Respiration, Artificial; Shock, Septic; Splanchnic Circulation; Vasoconstrictor Agents

2004
From mucolytic to antioxidant and liver protection: new aspects in the intensive care unit career of N-acetylcysteine.
    Critical care medicine, 2000, Volume: 28, Issue:12

    Topics: Acetylcysteine; Antioxidants; Critical Care; Expectorants; Humans; Liver Circulation; Shock, Septic

2000
[N-Acetylcysteine: new possibilities to use an old substance].
    Duodecim; laaketieteellinen aikakauskirja, 1999, Volume: 115, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Antioxidants; Free Radical Scavengers; Glutathione; Humans; Liver Failure; Oxidative Stress; Randomized Controlled Trials as Topic; Shock, Septic

1999

Trials

7 trial(s) available for acetylcysteine and Shock, Septic

ArticleYear
Influence of N-acetylcysteine on indirect indicators of tissue oxygenation in septic shock patients: results from a prospective, randomized, double-blind study.
    Critical care medicine, 1994, Volume: 22, Issue:11

    Topics: Acetylcysteine; Adult; Combined Modality Therapy; Double-Blind Method; Female; Hemodynamics; Humans; Male; Middle Aged; Monitoring, Physiologic; Oxygen Consumption; Prospective Studies; Shock, Septic; Statistics, Nonparametric; Survival Rate

1994
N-acetyl-L-cysteine depresses cardiac performance in patients with septic shock.
    Critical care medicine, 1996, Volume: 24, Issue:8

    Topics: Acetylcysteine; Aged; APACHE; Catecholamines; Double-Blind Method; Female; Heart; Hemodynamics; Humans; Intensive Care Units; Male; Middle Aged; Prospective Studies; Shock, Septic

1996
The effects of intravenous antioxidants in patients with septic shock.
    Free radical biology & medicine, 1997, Volume: 23, Issue:5

    Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Antioxidants; Ascorbic Acid; Drug Therapy, Combination; Free Radicals; Hemodynamics; Humans; Injections, Intravenous; Lipid Peroxides; Male; Middle Aged; Nitrites; Oxidation-Reduction; Shock, Septic; Vitamin E

1997
Does N-acetyl-L-cysteine influence cytokine response during early human septic shock?
    Chest, 1998, Volume: 113, Issue:6

    Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Antigens, CD; Double-Blind Method; Female; Hemodynamics; Humans; Infusions, Intravenous; Interleukin-10; Interleukin-6; Interleukin-8; Interleukins; Lactic Acid; Lung Compliance; Male; Middle Aged; Oxygen Consumption; Prospective Studies; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Shock, Septic; Tumor Necrosis Factor-alpha

1998
The effect of glutathione and N-acetylcysteine on lipoperoxidative damage in patients with early septic shock.
    American journal of respiratory and critical care medicine, 2000, Volume: 161, Issue:6

    Topics: Acetylcysteine; Adult; Aged; Antioxidants; APACHE; Critical Care; Female; Glutathione; Humans; Infusions, Intravenous; Lipid Peroxidation; Male; Middle Aged; Shock, Septic; Survival Rate; Treatment Outcome

2000
N-acetylcysteine increases liver blood flow and improves liver function in septic shock patients: results of a prospective, randomized, double-blind study.
    Critical care medicine, 2000, Volume: 28, Issue:12

    Topics: Acetylcysteine; Adult; Aged; Blood Flow Velocity; Coloring Agents; Double-Blind Method; Female; Free Radical Scavengers; Hemodynamics; Humans; Indocyanine Green; Infusions, Intravenous; Injections, Intravenous; Lidocaine; Liver; Liver Circulation; Liver Function Tests; Male; Metabolic Clearance Rate; Microsomes, Liver; Middle Aged; Oxygen Consumption; Prospective Studies; Shock, Septic; Survival Analysis

2000
N-acetylcysteine reduces respiratory burst but augments neutrophil phagocytosis in intensive care unit patients.
    Critical care medicine, 2001, Volume: 29, Issue:2

    Topics: Acetylcysteine; Adult; Analysis of Variance; APACHE; Female; Flow Cytometry; Free Radical Scavengers; Hospital Mortality; Humans; Infusions, Intravenous; Length of Stay; Male; Middle Aged; Neutrophils; Phagocytosis; Prospective Studies; Respiratory Burst; Shock, Septic; Survival Analysis; Time Factors

2001

Other Studies

18 other study(ies) available for acetylcysteine and Shock, Septic

ArticleYear
Efficacy of two FDA-approved drug combination in a mouse model of staphylococcal enterotoxin B-induced shock.
    Military medicine, 2013, Volume: 178, Issue:9

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Chemokine CCL2; Dexamethasone; Disease Models, Animal; Drug Therapy, Combination; Enterotoxins; Female; Free Radical Scavengers; Interferon-gamma; Interleukin-2; Interleukin-6; Lung; Male; Mice; Shock, Septic

2013
Pivotal role of glutathione depletion in plasma-induced endothelial oxidative stress during sepsis.
    Critical care medicine, 2008, Volume: 36, Issue:8

    Topics: Acetylcysteine; Adult; Aged; APACHE; Cell Death; Endothelium, Vascular; Female; Free Radical Scavengers; Glutathione; Humans; Intensive Care Units; Male; Middle Aged; Oxidative Stress; Reactive Oxygen Species; Shock, Septic

2008
The proteasome as a lipopolysaccharide-binding protein in macrophages: differential effects of proteasome inhibition on lipopolysaccharide-induced signaling events.
    Journal of immunology (Baltimore, Md. : 1950), 2003, Aug-01, Volume: 171, Issue:3

    Topics: Acetylcysteine; Acute-Phase Proteins; Animals; Carrier Proteins; Cell Line; Chymotrypsin; Cross-Linking Reagents; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Down-Regulation; Enzyme Activation; Escherichia coli; Glutamate Synthase; Leupeptins; Lipopolysaccharides; Macrophages; Macrophages, Peritoneal; Membrane Glycoproteins; Membrane Proteins; Methanosarcina; Mice; Mice, Inbred C3H; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Phosphorylation; Proteasome Endopeptidase Complex; Shock, Septic; Signal Transduction; Tritium

2003
Is there a place for N-acetylcysteine in the treatment of septic shock?
    Critical care (London, England), 2004, Volume: 8, Issue:2

    Topics: Acetylcysteine; Antioxidants; Hemodynamics; Humans; Lidocaine; Liver; Liver Circulation; Shock, Septic

2004
N-acetylcysteine decreases lactate signal intensities in liver tissue and improves liver function in septic shock patients, as shown by magnetic resonance spectroscopy: extended case report.
    Critical care (London, England), 2004, Volume: 8, Issue:2

    Topics: Acetylcysteine; Adult; Aged; Antioxidants; Female; Hemodynamics; Humans; Lactates; Lidocaine; Liver; Liver Circulation; Liver Function Tests; Magnetic Resonance Spectroscopy; Male; Middle Aged; Oxygen Consumption; Prospective Studies; Shock, Septic; Signal Transduction; Survival Analysis; Vasoconstriction

2004
N-acetylcysteine in clinical sepsis: a difficult marriage.
    Critical care (London, England), 2004, Volume: 8, Issue:4

    Topics: Acetylcysteine; Cytokines; Gastric Mucosa; Humans; Intensive Care Units; Oxidative Stress; Oxygen Consumption; Randomized Controlled Trials as Topic; Sepsis; Shock, Septic

2004
Multiple factors contributing to lipopolysaccharide-induced reactivity changes in rabbit pulmonary artery.
    Sheng li xue bao : [Acta physiologica Sinica], 2005, Dec-25, Volume: 57, Issue:6

    Topics: Acetylcysteine; Animals; Carbon Monoxide; Hypertension, Pulmonary; Lipopolysaccharides; Male; Nitric Oxide; Pulmonary Artery; Rabbits; Shock, Septic

2005
Key inflammatory signaling pathways are regulated by the proteasome.
    Shock (Augusta, Ga.), 2006, Volume: 25, Issue:5

    Topics: Acetylcysteine; Animals; Cell Survival; Chymotrypsin; Gene Expression Regulation, Enzymologic; Inflammation; Lipopolysaccharides; Macrophages; Mice; Oligonucleotide Array Sequence Analysis; Proteasome Endopeptidase Complex; Shock, Septic; Signal Transduction; Toll-Like Receptor 4

2006
Post-treatment with N-acetylcysteine ameliorates endotoxin shock-induced organ damage in conscious rats.
    Life sciences, 2006, Oct-19, Volume: 79, Issue:21

    Topics: Acetylcysteine; Animals; Blood Pressure; Cytokines; Drug Administration Schedule; Free Radical Scavengers; Heart; Heart Rate; Kidney; Kidney Function Tests; Lipopolysaccharides; Liver; Liver Function Tests; Male; Multiple Organ Failure; Myocardium; Rats; Rats, Inbred WKY; Shock, Septic

2006
Preclinical trial of L-arginine monotherapy alone or with N-acetylcysteine in septic shock.
    Critical care medicine, 2006, Volume: 34, Issue:11

    Topics: Acetylcysteine; Animals; Arginine; Dogs; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Free Radical Scavengers; Immunotherapy; Nitric Oxide; Parenteral Nutrition; Proportional Hazards Models; Random Allocation; Shock, Septic; Survival Analysis

2006
Effects of N-acetyl-L-cysteine on regional blood flow during endotoxic shock.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1995, Volume: 27, Issue:5

    Topics: Acetylcysteine; Animals; Dogs; Femoral Artery; Free Radical Scavengers; Hemodynamics; Mesenteric Arteries; Oxygen; Regional Blood Flow; Renal Artery; Shock, Septic

1995
Effects of N-acetylcysteine in endotoxic shock.
    Journal of critical care, 1994, Volume: 9, Issue:4

    Topics: Acetylcysteine; Analysis of Variance; Animals; Blood Pressure; Cardiac Output; Disease Models, Animal; Dogs; Lactates; Random Allocation; Respiratory Function Tests; Shock, Septic; Tumor Necrosis Factor-alpha; Vasodilator Agents

1994
Protective effect of N-acetylcysteine on multiple organ failure induced by zymosan in the rat.
    Critical care medicine, 1999, Volume: 27, Issue:8

    Topics: Acetylcysteine; Animals; Body Weight; Disease Models, Animal; Drug Evaluation, Preclinical; Free Radical Scavengers; Leukocyte Count; Male; Multiple Organ Failure; Nitrates; Nitric Oxide; Peritonitis; Random Allocation; Rats; Rats, Sprague-Dawley; Shock, Septic; Survival Analysis; Time Factors; Zymosan

1999
Modulation of murine macrophage function by N-acetylcysteine in a model of endotoxic shock.
    BioFactors (Oxford, England), 1999, Volume: 10, Issue:4

    Topics: Acetylcysteine; Animals; Cell Adhesion; Chemotaxis; Disease Models, Animal; Escherichia coli; Female; In Vitro Techniques; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; N-Formylmethionine Leucyl-Phenylalanine; Phagocytosis; Shock, Septic; Superoxides; Tumor Necrosis Factor-alpha

1999
Anti-oxidants as modulators of immune function.
    Immunology and cell biology, 2000, Volume: 78, Issue:1

    Topics: Acetylcysteine; Adjuvants, Immunologic; Adult; Aged; Aging; Animals; Antioxidants; Cell Adhesion; Disease Models, Animal; Female; Humans; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Shock, Septic; Vitamin E

2000
Priming for enhanced alveolar fibrin deposition after hemorrhagic shock: role of tumor necrosis factor.
    American journal of respiratory cell and molecular biology, 2000, Volume: 22, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Blood Coagulation Disorders; Bronchoalveolar Lavage Fluid; Capillary Leak Syndrome; Disseminated Intravascular Coagulation; Fibrin; Fibrinolysis; Gene Expression Regulation; Lipopolysaccharides; Lipoproteins; Macrophage Activation; Macrophages, Alveolar; Male; Models, Biological; Neutrophils; NF-kappa B; Oxidative Stress; Plasminogen Activator Inhibitor 1; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Respiratory Distress Syndrome; Shock, Hemorrhagic; Shock, Septic; Thromboplastin; Transcription, Genetic; Tumor Necrosis Factor-alpha

2000
Ascorbic acid and N-acetylcysteine improve in vitro the function of lymphocytes from mice with endotoxin-induced oxidative stress.
    Free radical research, 2001, Volume: 35, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Cell Adhesion; Cells, Cultured; Chemotaxis; Escherichia coli; Female; In Vitro Techniques; Lipopolysaccharides; Lymphocytes; Mice; Mice, Inbred BALB C; Oxidative Stress; Phagocytosis; Reactive Oxygen Species; Shock, Septic; Tumor Necrosis Factor-alpha

2001
[Glutathione and N-acetylcysteine in the prevention of free-radical damage in the initial phase of septic shock].
    Recenti progressi in medicina, 2002, Volume: 93, Issue:2

    Topics: Acetylcysteine; Free Radical Scavengers; Free Radicals; Glutathione; Humans; Shock, Septic

2002