acetylcysteine has been researched along with Scleroderma, Systemic in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Khodamoradi, Z; Mehrabi, S; Moradi, MM; Nazarinia, MA | 1 |
| Kim, KJ; Moon, SJ; Park, KS; Tagkopoulos, I | 1 |
| Borghese, F; Pisarri, S; Rosato, E; Salsano, F | 1 |
| Amoroso, A; Barbano, B; Cianci, R; Gigante, A; Menghi, G; Pisarri, S; Rosato, E; Rossi, C; Salsano, F; Zardi, EM | 1 |
| Jimenez, SA; Kendzicky, A; Koch, AE; Phillips, K; Piera-Velazquez, S; Pinney, AJ; Seibold, JR; Talia, NN; Tsou, PS | 1 |
| Lota, HK; Wells, AU | 1 |
| D'Alfonso, C; Failli, P; Generini, S; Giovannelli, L; Matucci-Cerinic, M; Orsi, S; Palmieri, L; Pignone, A; Rosso, AD; Stanflin, N; Zilletti, L | 1 |
| Chizzolini, C; Dayer, JM; Fineschi, S; Guerne, PA; Reith, W | 1 |
| Amico, D; Gabrielli, A; Giacomelli, R; Matucci-Cerinic, M; Salsano, F; Sambo, P; Valentini, G | 1 |
| Baroni, SS; Dusi, S; Gabrielli, A; Luchetti, M; Orlandini, G; Paroncini, P; Sambo, P | 1 |
| Clements, PJ; Furst, DE; Harris, R; Levy, J; Paulus, HE; Ross, M | 1 |
| Bianchi, V; Ghirardo, G; Rovetta, G | 1 |
1 review(s) available for acetylcysteine and Scleroderma, Systemic
| Article | Year |
|---|---|
The evolving pharmacotherapy of pulmonary fibrosis.
Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Interstitial Pneumonias; Immunosuppressive Agents; Indoles; Lung Diseases, Interstitial; Pulmonary Fibrosis; Pyridones; Randomized Controlled Trials as Topic; Sarcoidosis, Pulmonary; Scleroderma, Systemic; Treatment Outcome | 2013 |
4 trial(s) available for acetylcysteine and Scleroderma, Systemic
| Article | Year |
|---|---|
Effects of N-acetylcysteine on Pulmonary Functions in Patients with Systemic Sclerosis: A Randomized Double Blind, Placebo Controlled Study.
Topics: Acetylcysteine; Adult; Double-Blind Method; Female; Free Radical Scavengers; Humans; Lung; Lung Diseases, Interstitial; Male; Middle Aged; Respiratory Function Tests; Scleroderma, Systemic; Treatment Outcome; Young Adult | 2020 |
N-acetylcysteine infusion reduces the resistance index of renal artery in the early stage of systemic sclerosis.
Topics: Acetylcysteine; Female; Free Radical Scavengers; Humans; Male; Microscopic Angioscopy; Middle Aged; Renal Artery; Renal Artery Obstruction; Scleroderma, Systemic; Vascular Resistance | 2009 |
Intravenous N-acetylcysteine for treatment of Raynaud's phenomenon secondary to systemic sclerosis: a pilot study.
Topics: Acetylcysteine; Adult; Cold Temperature; Female; Follow-Up Studies; Free Radical Scavengers; Humans; Injections, Intravenous; Male; Middle Aged; Oxidative Stress; Pilot Projects; Plethysmography; Raynaud Disease; Scleroderma, Systemic; Skin Ulcer; Treatment Outcome | 2001 |
Measurement of clinical change in progressive systemic sclerosis: a 1 year double-blind placebo-controlled trial of N-acetylcysteine.
Topics: Acetylcysteine; Adult; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Prospective Studies; Scleroderma, Systemic; Skin; Time Factors | 1979 |
7 other study(ies) available for acetylcysteine and Scleroderma, Systemic
| Article | Year |
|---|---|
Network-based modeling of drug effects on disease module in systemic sclerosis.
Topics: Acetylcysteine; Dasatinib; Drug Repositioning; Female; Fibrosis; Genome-Wide Association Study; Humans; Imatinib Mesylate; Indoles; Male; Molecular Targeted Therapy; Protein Kinase Inhibitors; Scleroderma, Systemic; Signal Transduction | 2020 |
The treatment with N-acetylcysteine of Raynaud's phenomenon and ischemic ulcers therapy in sclerodermic patients: a prospective observational study of 50 patients.
Topics: Acetylcysteine; Female; Fingers; Free Radical Scavengers; Humans; Infusions, Intravenous; Ischemia; Male; Middle Aged; Raynaud Disease; Scleroderma, Systemic; Skin; Skin Ulcer; Treatment Outcome | 2009 |
Effect of oxidative stress on protein tyrosine phosphatase 1B in scleroderma dermal fibroblasts.
Topics: Acetylcysteine; Cells, Cultured; Collagen Type I; Fibroblasts; Free Radical Scavengers; Humans; Oxidative Stress; Phosphorylation; Platelet-Derived Growth Factor; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Reactive Oxygen Species; Receptors, Platelet-Derived Growth Factor; Scleroderma, Systemic; Skin; Superoxides | 2012 |
Effect of N-acetyl-L-cysteine on peroxynitrite and superoxide anion production of lung alveolar macrophages in systemic sclerosis.
Topics: Acetylcysteine; Bronchoalveolar Lavage Fluid; Female; Humans; Immunohistochemistry; Lung; Macrophages, Alveolar; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Scleroderma, Systemic; Superoxides | 2002 |
Proteasome blockade exerts an antifibrotic activity by coordinately down-regulating type I collagen and tissue inhibitor of metalloproteinase-1 and up-regulating metalloproteinase-1 production in human dermal fibroblasts.
Topics: Acetylcysteine; Anthracenes; Boronic Acids; Bortezomib; Collagen Type I; Dose-Response Relationship, Drug; Down-Regulation; Extracellular Matrix; Fibroblasts; Fibrosis; Genes, jun; Humans; JNK Mitogen-Activated Protein Kinases; Leupeptins; Matrix Metalloproteinase 1; Phosphorylation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-jun; Pyrazines; RNA Polymerase II; RNA, Messenger; Scleroderma, Systemic; Skin; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta; Up-Regulation | 2006 |
Oxidative stress in scleroderma: maintenance of scleroderma fibroblast phenotype by the constitutive up-regulation of reactive oxygen species generation through the NADPH oxidase complex pathway.
Topics: Acetylcysteine; Allopurinol; alpha-Tocopherol; Biphenyl Compounds; Cell Division; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Fibroblasts; Growth Substances; Humans; Hydrogen Peroxide; Microscopy, Confocal; NADPH Oxidases; Onium Compounds; Oxidative Stress; Phenotype; Phosphoproteins; Protein Transport; Reactive Oxygen Species; Rotenone; Scleroderma, Localized; Scleroderma, Systemic; Skin; Up-Regulation | 2001 |
[The action of sulfhydryl substances in fibrosis in joint pathology].
Topics: Acetylcysteine; Cysteamine; Dupuytren Contracture; Humans; Joint Diseases; Scleroderma, Systemic; Sulfhydryl Compounds | 1971 |