acetylcysteine and Respiratory Distress Syndrome

acetylcysteine has been researched along with Respiratory Distress Syndrome in 65 studies

Research

Studies (65)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (6.15)	18.7374
1990's	21 (32.31)	18.2507
2000's	27 (41.54)	29.6817
2010's	7 (10.77)	24.3611
2020's	6 (9.23)	2.80

Authors

Authors	Studies
Adir, Y; Alyan, M; Arber Raviv, S; Dor, E; Egorov, E; Farkash, S; Flikshtain, OD; Gal, Y; Harush, MY; Kaneti, G; Korach-Rechtman, H; Koren, L; Mekies, LN; Nudelman, I; Pieters, C; Saadya, A; Schroeder, A; Shainsky, J; Shklover, J; Zano, A	1
Izquierdo-Alonso, JL; Peces-Barba, G; Pérez-Rial, S; Rivera, CG	1
Baratashvili, N; Gvaramia, L; Kandelaki, M; Samsonia, M	1
Calkovska, A; Hanusrichterova, J; Kolomaznik, M; Kosutova, P; Mikolka, P; Mokra, D; Vatecha, M; Zila, I	1
Bhatnagar, M; Jaiswal, N; Shah, H	1
Zhang, S; Zhang, X; Zhao, Y	1
Lambert, AA; Moon, KK; Parker, AM	1
Kang, S	1
Chao, J; Chao, L; Chen, CW; Huang, YW; Lin, CF; Lin, WC; Lin, YS	1
Ditch, KL; Dube, KM; Hills, L	1
Bhullar, IS; Royall, N; Smith, H; Warren, B	1
Ghahremani, MH; Hajibabayee, M; Khajavi, MR; Mandegari, A; Mojtahedzadeh, M; Moradi, M; Najafi, A; Soltan-Sharifi, MS	1
Cansu, A; Erol, MM; Erturk, E; Tatli, O; Turedi, S; Yeniocak, S	1
Chen, J; Guan, XD; Li, XF; Ouyang, B; Wu, JF	1
Baboolal, HA; Bloch, KD; Ichinose, F; Kawai, N; Ullrich, R; Zapol, WM	1
Hales, CA; Jafari, B; Li, LF; Ouyang, B; Quinn, DA	1
Bouchier-Hayes, D; Condron, C; Kearns, S; Murray, P; Power, C; Street, J; Thornes, B; Timlin, M; Toomey, D	1
Adhikari, N; Burns, KE; Meade, MO	2
Atik, U; Cinel, I; Cinel, L; Ercan, B; Ercil, M; Kanik, A; Koksel, O; Ozdulger, A; Tamer, L	1
Eriksson, C; Jansson, AH; Wang, X	1
Balkan, A; Balkan, M; Bilgic, H; Erdem, O; Kiliç, S; Korkmaz, A; Kutsal, O; Yasar, M	1
Andrades, M; da Cunha, AA; Dal-Pizzol, F; Echer, IC; Lucchiari, N; Menna-Barreto, S; Moreira, JC; Reinke, A; Ritter, C; Rocha, J; Streck, EL	1
Cross, CE; Halliwell, B; van Asbeck, BS	1
Bozkurt, AK; Cortelekoglu, T; Koksal, C; Konukoglu, D; Musellim, B; Sayin, AG; Sirin, G; Ustundag, N	1
Alkan, A; Alsancak, G; Cerçi, C; Ergin, C; Eroğlu, E; Eroğlu, F	1
Benjamin, SP; Fernando, ME; Jayanth, JJ; Preetha, B	1
Barnes, K; Biswal, S; Crow, MT; Dodd-O, JM; Grigoryev, DN; Hassoun, PM; Kensler, TW; Mitzner, W; Papaiahgari, S; Reddy, NM; Reddy, SP; Reddy, SR; Tuder, RM; Yamamoto, M; Yerrapureddy, A	1
Abdollahi, M; Mohammadirad, A; Mojtahedzadeh, M; Moradi, M; Najafi, A; Reza Khajavi, M; Reza Rouini, M; Soltan-Sharifi, MS	1
Beltz, EA; Bream-Rouwenhorst, HR; Moores, KG; Ross, MB	1
Chen, HI; Kao, SJ; Liu, DD	1
Molnár, Z	1
Flierl, MA; Hoesel, LM; McClintock, SD; Niederbichler, AD; Pianko, MJ; Reuben, JS; Rittirsch, D; Sarma, JV; Smith, M; Stone, W; Ward, PA; Yang, H	1
Hales, CA; Jafari, B; Quinn, DA; Syrkina, O	1
Bernard, GR; Christman, BW	1
De Wit, N; Gillet, R; Huyghens, L; Spapen, H; Zhang, H	1
Beehler, CJ; Hybertson, BM; Leff, JA; Repine, JE; Shanley, PF; Wilke, CP	1
Domenighetti, G; Laverrière, MC; Perret, C; Ritz, R; Schaller, MD; Suter, PM	1
Barth, P; Feddersen, CO; Püchner, A; von Wichert, P	1
Feihl, F; Laurent, T; Markert, M; Perret, C; Schaller, MD	1
Blackwell, TR; Blackwell, TS; Christman, BW; Christman, JW; Holden, EP	1
Benson, PF; Doctrow, SR; Fink, MP; Gonzalez, PK; Malfroy, B; Menconi, MJ; Zhuang, J	1
Amsel, B; Bossaert, L; De Backer, WA; Hiemstra, PS; Jorens, PG; van Noort, P; van Overveld, FJ	1
Kasper, M; Morin, AM; Suhayda, A; von Schmädel, E; Zähringer, J	1
Arons, MM; Bernard, GR; Morris, PE; Paz, HL; Russell, JA; Wheeler, AP; Wright, PE	1
Domenighetti, G; Perret, C; Ritz, R; Schaller, MD; Suter, PM	1
Fukumoto, T; Moriuchi, H; Yuizono, T; Zaha, M	1
Ruffmann, R	1
Lee, A; Walsh, TS	1
Conti, A; De Gaudio, AR; Masoni, M; Novelli, G; Ortolani, O	1
Fan, J; Kapus, A; Li, YH; Marshall, JC; Rizoli, S; Rotstein, OD	1
Bossaert, L; De Backer, W; Jorens, PG; Lenz, AG; Maier, KL; Meyer, B; Van Overveld, F	1
Fan, J; Li, YH; Oreopoulos, GD; Rotstein, OD; Shek, PN; Suntres, ZE	1
Gon, Y; Hashimoto, S; Horie, T; Koura, T; Matsumoto, K; Nakayama, T; Takeshita, I	1
Eaton, S; Martin, G	1
Bulger, EM; Garcia, I; Maier, RV	1
Bud, MI; Herlevsen, P; Jepsen, S; Klausen, NO; Knudsen, P	1
Ruffmann, R; Wendel, A	1
Bernard, GR	2
Brigham, KL	1
Bebout, DE; Glennow, C; Gray, AT; Mathieu-Costello, O; Natterson, PD; Wagner, PD	1
Braganza, JM; Holmes, AM; Kisher, R; Ku, R; Morton, AR; Stalley, L	1
Andersen, JB; Bud, MI; Hjortsø, E; Jensen, NK; Jones, R; Qvist, J; Reid, LM; Thomsen, JL; Wiberg-Jørgensen, F; Zapol, WM	1
Saldeen, T; Sandhagen, B; Wegener, T	1

Reviews

14 review(s) available for acetylcysteine and Respiratory Distress Syndrome

Article	Year
N-acetylcysteine for prevention and treatment of COVID-19: Current state of evidence and future directions. Journal of infection and public health, 2022, Volume: 15, Issue:12 Topics: Acetylcysteine; COVID-19 Drug Treatment; Humans; Immunotherapy; Respiratory Distress Syndrome; SARS-CoV-2	2022
[Progress of the antioxidant effect of N-acetylcysteine in treatment of acute respiratory distress syndrome]. Zhonghua wei zhong bing ji jiu yi xue, 2020, Volume: 32, Issue:12 Topics: Acetylcysteine; Animals; Antioxidants; China; Oxidative Stress; Respiratory Distress Syndrome	2020
Pharmacologic therapies for adults with acute lung injury and acute respiratory distress syndrome. The Cochrane database of systematic reviews, 2004, Oct-18, Issue:4 Topics: Acetylcysteine; Adrenal Cortex Hormones; Alprostadil; Humans; Pulmonary Surfactants; Randomized Controlled Trials as Topic; Respiratory Distress Syndrome	2004
Pharmacologic treatments for acute respiratory distress syndrome and acute lung injury: systematic review and meta-analysis. Treatments in respiratory medicine, 2004, Volume: 3, Issue:5 Topics: Acetylcysteine; Adrenal Cortex Hormones; Alprostadil; Humans; Pentoxifylline; Randomized Controlled Trials as Topic; Respiration, Artificial; Respiratory Distress Syndrome; Surface-Active Agents; Vasodilator Agents	2004
Recent developments in the management of acute respiratory distress syndrome in adults. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2008, Jan-01, Volume: 65, Issue:1 Topics: Acetylcysteine; Acute Disease; Adrenal Cortex Hormones; Adult; Albuterol; Bronchodilator Agents; Expectorants; Fluid Therapy; Humans; Nitric Oxide; Prone Position; Prostaglandins; Pulmonary Surfactants; Respiration, Artificial; Respiratory Distress Syndrome; Tidal Volume	2008
Antilipid mediator and antioxidant therapy in adult respiratory distress syndrome. New horizons (Baltimore, Md.), 1993, Volume: 1, Issue:4 Topics: Acetylcysteine; Adrenal Cortex Hormones; Antioxidants; Clinical Trials as Topic; Disease Models, Animal; Epoprostenol; Humans; Inflammation; Intensive Care Units; Leukotrienes; Lipid Peroxidation; Middle Aged; Platelet Activating Factor; Respiratory Distress Syndrome; Thromboxanes; Treatment Failure	1993
[Acetylcysteine: a promising antioxidant for cardiorespiratory disorders]. Nederlands tijdschrift voor geneeskunde, 1994, Apr-02, Volume: 138, Issue:14 Topics: Acetaminophen; Acetylcysteine; Acquired Immunodeficiency Syndrome; Antioxidants; Chemical and Drug Induced Liver Injury; Humans; Myocardial Reperfusion Injury; Nitrates; Reactive Oxygen Species; Respiratory Distress Syndrome	1994
Role of oxidant stress in the adult respiratory distress syndrome: evaluation of a novel antioxidant strategy in a porcine model of endotoxin-induced acute lung injury. Shock (Augusta, Ga.), 1996, Volume: 6 Suppl 1 Topics: Acetylcysteine; Adult; Animals; Catalase; Disease Models, Animal; Endotoxins; Ethylenediamines; Free Radical Scavengers; Humans; Lipopolysaccharides; Lung; Lung Injury; Organometallic Compounds; Oxidative Stress; Reactive Oxygen Species; Respiratory Distress Syndrome; Superoxide Dismutase; Swine; Thiourea	1996
N-acetylcysteine administration in the critically ill. Intensive care medicine, 1999, Volume: 25, Issue:5 Topics: Acetylcysteine; Animals; Antioxidants; Cardiovascular System; Critical Illness; Free Radical Scavengers; Humans; Immune System; Liver Failure; Respiratory Distress Syndrome	1999
Clinical developments for treating ARDS. Expert opinion on investigational drugs, 2002, Volume: 11, Issue:1 Topics: Acetylcysteine; Adrenal Cortex Hormones; Animals; Anticoagulants; Antioxidants; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Expectorants; Hemodynamics; Humans; Hydrostatic Pressure; Immunotherapy; Nutritional Physiological Phenomena; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Therapy	2002
GSH rescue by N-acetylcysteine. Klinische Wochenschrift, 1991, Nov-15, Volume: 69, Issue:18 Topics: Acetylcysteine; Acquired Immunodeficiency Syndrome; Glutathione; Humans; Pulmonary Fibrosis; Respiratory Distress Syndrome	1991
N-acetylcysteine in experimental and clinical acute lung injury. The American journal of medicine, 1991, Sep-30, Volume: 91, Issue:3C Topics: Acetylcysteine; Animals; Clinical Trials as Topic; Endotoxins; Free Radical Scavengers; Glutathione; Granulocytes; Humans; Lung Diseases; Models, Biological; Respiratory Distress Syndrome	1991
Oxidant stress and adult respiratory distress syndrome. The European respiratory journal. Supplement, 1990, Volume: 11 Topics: Acetylcysteine; Animals; Free Radicals; Humans; Lung; Oxygen; Respiratory Distress Syndrome	1990
ARDS after accidental inhalation of zinc chloride smoke. Intensive care medicine, 1988, Volume: 14, Issue:1 Topics: Acetylcysteine; Adult; Anti-Inflammatory Agents, Non-Steroidal; Chlorides; Humans; Lung; Military Personnel; Respiratory Distress Syndrome; Zinc; Zinc Compounds	1988

Trials

11 trial(s) available for acetylcysteine and Respiratory Distress Syndrome

Article	Year
The role of glutathione-S-transferase polymorphisms on clinical outcome of ALI/ARDS patient treated with N-acetylcysteine. Respiratory medicine, 2009, Volume: 103, Issue:3 Topics: Acetylcysteine; Acute Lung Injury; Adult; Antioxidants; Case-Control Studies; Chi-Square Distribution; Drug Administration Schedule; Female; Gene Frequency; Genotype; Glutathione Transferase; Humans; Male; Middle Aged; Oxidative Stress; Polymorphism, Genetic; Respiratory Distress Syndrome; Single-Blind Method; Treatment Outcome	2009
Improvement by N-acetylcysteine of acute respiratory distress syndrome through increasing intracellular glutathione, and extracellular thiol molecules and anti-oxidant power: evidence for underlying toxicological mechanisms. Human & experimental toxicology, 2007, Volume: 26, Issue:9 Topics: Acetylcysteine; Adult; Antioxidants; APACHE; Biomarkers; Blood Platelets; Female; Glutathione; Humans; Infusions, Intravenous; Male; Middle Aged; Oxidative Stress; Respiratory Distress Syndrome; Sulfhydryl Compounds; Treatment Outcome; Up-Regulation	2007
N-acetylcysteine enhances recovery from acute lung injury in man. A randomized, double-blind, placebo-controlled clinical study. Chest, 1994, Volume: 105, Issue:1 Topics: Acetylcysteine; Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Lung; Lung Injury; Male; Middle Aged; Oxygen Consumption; Oxygen Inhalation Therapy; Placebos; Respiration, Artificial; Respiratory Distress Syndrome; Risk Factors; Severity of Illness Index; Survival Rate; Time Factors; Treatment Outcome	1994
Oxidant-antioxidant balance in granulocytes during ARDS. Effect of N-acetylcysteine. Chest, 1996, Volume: 109, Issue:1 Topics: Acetylcysteine; Acridines; Antioxidants; Double-Blind Method; Female; Glutathione; Granulocytes; Humans; Indicators and Reagents; Infusions, Intravenous; Leukocyte Elastase; Luminescent Measurements; Luminol; Male; Middle Aged; Oxidants; Pancreatic Elastase; Placebos; Reactive Oxygen Species; Respiratory Distress Syndrome	1996
N-acetylcysteine pretreatment of cardiac surgery patients influences plasma neutrophil elastase and neutrophil influx in bronchoalveolar lavage fluid. Intensive care medicine, 1996, Volume: 22, Issue:9 Topics: Acetylcysteine; Aged; Bronchoalveolar Lavage Fluid; Cardiac Surgical Procedures; Double-Blind Method; Female; Free Radical Scavengers; Humans; Leukocyte Elastase; Male; Middle Aged; Neutrophils; Premedication; Respiratory Distress Syndrome	1996
A trial of antioxidants N-acetylcysteine and procysteine in ARDS. The Antioxidant in ARDS Study Group. Chest, 1997, Volume: 112, Issue:1 Topics: Acetylcysteine; Adult; Antioxidants; Bilirubin; Bronchoalveolar Lavage Fluid; Cardiac Output; Cysteine; Double-Blind Method; Free Radical Scavengers; Glutathione; Humans; Middle Aged; Prospective Studies; Pyrrolidonecarboxylic Acid; Respiration, Artificial; Respiratory Distress Syndrome; Thiazoles; Thiazolidines; Time Factors	1997
Treatment with N-acetylcysteine during acute respiratory distress syndrome: a randomized, double-blind, placebo-controlled clinical study. Journal of critical care, 1997, Volume: 12, Issue:4 Topics: Acetylcysteine; Adult; Aged; Blood Coagulation; Double-Blind Method; Expectorants; Female; Hemodynamics; Humans; Infusions, Intravenous; Male; Middle Aged; Oxygen; Pulmonary Gas Exchange; Respiration, Artificial; Respiratory Distress Syndrome	1997
Protective effects of N-acetylcysteine and rutin on the lipid peroxidation of the lung epithelium during the adult respiratory distress syndrome. Shock (Augusta, Ga.), 2000, Volume: 13, Issue:1 Topics: Acetylcysteine; Adult; Aged; APACHE; Breath Tests; Bronchoalveolar Lavage Fluid; Ethane; Female; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Humans; Infusions, Intravenous; Lipid Peroxidation; Lung; Male; Malondialdehyde; Middle Aged; Respiratory Distress Syndrome; Respiratory Mucosa; Rutin; Time Factors	2000
Antioxidant treatment with N-acetylcysteine during adult respiratory distress syndrome: a prospective, randomized, placebo-controlled study. Critical care medicine, 1992, Volume: 20, Issue:7 Topics: Acetylcysteine; Adult; Aged; Antithrombin III; Double-Blind Method; Female; Fibrinogen; Humans; Lung Compliance; Male; Middle Aged; Oxygen; Partial Pressure; Platelet Count; Prospective Studies; Respiratory Distress Syndrome	1992
N-acetylcysteine in experimental and clinical acute lung injury. The American journal of medicine, 1991, Sep-30, Volume: 91, Issue:3C Topics: Acetylcysteine; Animals; Clinical Trials as Topic; Endotoxins; Free Radical Scavengers; Glutathione; Granulocytes; Humans; Lung Diseases; Models, Biological; Respiratory Distress Syndrome	1991
Potential of N-acetylcysteine as treatment for the adult respiratory distress syndrome. The European respiratory journal. Supplement, 1990, Volume: 11 Topics: Acetylcysteine; Animals; Double-Blind Method; Free Radicals; Glutathione; Humans; Lymphocyte Activation; Methylprednisolone; Respiratory Distress Syndrome; Sheep	1990

Other Studies

41 other study(ies) available for acetylcysteine and Respiratory Distress Syndrome

Article	Year
Lung targeted liposomes for treating ARDS. Journal of controlled release : official journal of the Controlled Release Society, 2022, Volume: 346 Topics: Acetylcysteine; Animals; COVID-19; Humans; Inflammation; Lipopolysaccharides; Liposomes; Lung; Lung Diseases; Mice; Mice, Inbred C57BL; Nanoparticles; Respiratory Distress Syndrome; Tumor Necrosis Factor-alpha	2022
NEUROPROTECTIVE AND ANTIOXIDANT POTENTIAL OF MONTELUKAST-ACETYLCYSTEINE COMBINATION THERAPY FOR BRAIN PROTECTION IN PATIENTS WITH COVID-19 INDUCED PNEUMONIA. Georgian medical news, 2023, Issue:335 Topics: Acetylcysteine; Adult; Aged; Antioxidants; COVID-19; Diabetes Mellitus, Type 2; Humans; Interleukin-6; Microcirculation; Middle Aged; Oxygen; Pneumonia, Viral; Respiratory Distress Syndrome; SARS-CoV-2	2023
Efficiency of exogenous surfactant combined with intravenous N-acetylcysteine in two-hit rodent model of ARDS. Respiratory physiology & neurobiology, 2023, Volume: 316 Topics: Acetylcysteine; Animals; Antioxidants; Hyperoxia; Lung; Lung Injury; Pulmonary Surfactants; Rats; Rats, Wistar; Respiratory Distress Syndrome; Rodentia; Surface-Active Agents	2023
N-acetycysteine: A potential therapeutic agent in COVID-19 infection. Medical hypotheses, 2020, Volume: 144 Topics: Acetylcysteine; Antioxidants; COVID-19 Drug Treatment; Glutathione; Humans; Oxidation-Reduction; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Reactive Oxygen Species; Respiratory Distress Syndrome	2020
High-dose N-acetylcysteine in chronic obstructive pulmonary disease, prone positioning in acute respiratory distress syndrome, and continuous positive airway pressure and exhaled nitric oxide in obstructive sleep apnea. American journal of respiratory and critical care medicine, 2014, 01-15, Volume: 189, Issue:2 Topics: Acetylcysteine; Continuous Positive Airway Pressure; Free Radical Scavengers; Humans; Nitric Oxide; Prone Position; Pulmonary Disease, Chronic Obstructive; Respiratory Distress Syndrome; Sleep Apnea, Obstructive	2014
2014 American Thoracic Society International Conference. The Lancet. Respiratory medicine, 2014, Volume: 2, Issue:7 Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Asthma; Congresses as Topic; Eosinophilia; Expectorants; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Idiopathic Pulmonary Fibrosis; Indoles; Lung Neoplasms; Protein Kinase Inhibitors; Pulmonary Disease, Chronic Obstructive; Pyridones; Respiratory Distress Syndrome	2014
Kallistatin protects against sepsis-related acute lung injury via inhibiting inflammation and apoptosis. Scientific reports, 2015, Jul-22, Volume: 5 Topics: Acetylcysteine; Acute Lung Injury; Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Cell Line, Tumor; Down-Regulation; Epithelial Cells; Fas Ligand Protein; fas Receptor; Humans; Inflammation; Lipopolysaccharides; Lung; Mice; NF-kappa B; Reactive Oxygen Species; Respiratory Distress Syndrome; Sepsis; Serpins; Signal Transduction	2015
Use of Nebulized Heparin, Nebulized N-Acetylcysteine, and Nebulized Epoprostenol in a Patient With Smoke Inhalational Injury and Acute Respiratory Distress Syndrome. Journal of pharmacy practice, 2017, Volume: 30, Issue:6 Topics: Acetylcysteine; Administration, Inhalation; Anticoagulants; Antihypertensive Agents; Drug Therapy, Combination; Epoprostenol; Expectorants; Heparin; Humans; Male; Nebulizers and Vaporizers; Respiratory Distress Syndrome; Smoke Inhalation Injury; Young Adult	2017
Novel Treatment of Acute Respiratory Distress Syndrome after Chlorine Gas Inhalation Injury. The American surgeon, 2016, Volume: 82, Issue:8 Topics: Acetylcysteine; Albuterol; Anticoagulants; Bronchodilator Agents; Chemical Warfare Agents; Chlorine; Expectorants; Heparin; Humans; Male; Middle Aged; Respiratory Distress Syndrome; Respiratory Therapy	2016
Acute severe respiratory distress secondary to misuse of an N-acetylcysteine effervescent tablet. The American journal of emergency medicine, 2010, Volume: 28, Issue:7 Topics: Acetylcysteine; Administration, Oral; Aged; Antiviral Agents; Causality; Edema; Emergency Treatment; Glottis; Humans; Male; Medication Errors; Respiratory Aspiration; Respiratory Distress Syndrome; Solubility; Tablets	2010
[N-acetylcysteine (NAC) inhibited pulmonary fibrosis in acute respiratory distress syndrome (ARDS)]. Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, 2011, Volume: 23, Issue:10 Topics: Acetylcysteine; Cells, Cultured; Collagen; Fibroblasts; Glutathione; Humans; Lipopolysaccharides; Lung; Pulmonary Fibrosis; Respiratory Distress Syndrome	2011
Reactive oxygen species scavengers attenuate endotoxin-induced impairment of hypoxic pulmonary vasoconstriction in mice. Anesthesiology, 2002, Volume: 97, Issue:5 Topics: Acetylcysteine; Animals; Antioxidants; Cell Hypoxia; Endotoxins; Ethylenediamines; Female; Male; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Organometallic Compounds; Peroxidase; Pulmonary Circulation; Reactive Oxygen Species; Respiratory Distress Syndrome; RNA, Messenger; Vasoconstriction	2002
Intracellular glutathione in stretch-induced cytokine release from alveolar type-2 like cells. Respirology (Carlton, Vic.), 2004, Volume: 9, Issue:1 Topics: Acetylcysteine; Antioxidants; Blotting, Northern; Buthionine Sulfoximine; Cells, Cultured; Cytokines; Epithelial Cells; Glutathione; Humans; Interleukin-1; Interleukin-6; Interleukin-8; Isoprostanes; Lipid Peroxidation; NF-kappa B; Oxidative Stress; Pulmonary Alveoli; Respiratory Distress Syndrome; Stress, Mechanical; Transcription Factor AP-1	2004
N-acetylcysteine attenuates lung injury in a rodent model of fracture. Acta orthopaedica Scandinavica, 2004, Volume: 75, Issue:1 Topics: Acetylcysteine; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Femoral Fractures; Fracture Fixation, Intramedullary; Free Radical Scavengers; Lung; Male; Organ Size; Peroxidase; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome	2004
Effects of N-acetylcysteine on oxidant-antioxidant balance in oleic acid-induced lung injury. Experimental lung research, 2004, Volume: 30, Issue:6 Topics: Acetylcysteine; Animals; Antioxidants; Disease Models, Animal; Drug Administration Schedule; Female; Injections, Intravenous; Lung; Malondialdehyde; Oleic Acid; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Respiratory Distress Syndrome; Sodium-Potassium-Exchanging ATPase; Time Factors	2004
Effects of budesonide and N-acetylcysteine on acute lung hyperinflation, inflammation and injury in rats. Vascular pharmacology, 2005, Volume: 43, Issue:2 Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Budesonide; Chemokine CCL2; Chemokine CXCL1; Chemokine CXCL2; Chemokines, CXC; Dose-Response Relationship, Drug; Female; Free Radical Scavengers; Instillation, Drug; Interleukin-1; Interleukin-6; Lipopolysaccharides; Lung; Organ Size; Pneumonia; Rats; Rats, Wistar; Respiratory Distress Syndrome; Total Lung Capacity; Tumor Necrosis Factor-alpha	2005
Pulmonary protective effects of hyberbaric oxygen and N-acetylcysteine treatment in necrotizing pancreatitis. Physiological research, 2006, Volume: 55, Issue:1 Topics: Acetylcysteine; Animals; Ceruletide; Glutathione Peroxidase; Hyperbaric Oxygenation; Lung; Male; Malondialdehyde; Oxidative Stress; Pancreatitis, Acute Necrotizing; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Superoxide Dismutase	2006
Effects of N-acetylcysteine plus deferoxamine in lipopolysaccharide-induced acute lung injury in the rat. Critical care medicine, 2006, Volume: 34, Issue:2 Topics: Acetylcysteine; Animals; Bronchoalveolar Lavage Fluid; Deferoxamine; Disease Models, Animal; Interleukin-1; Lipopolysaccharides; Male; Oxidative Stress; Rats; Rats, Wistar; Respiratory Distress Syndrome; Siderophores; Tumor Necrosis Factor-alpha; Vasodilator Agents	2006
More antioxidants in sepsis: still paved with uncertainties. Critical care medicine, 2006, Volume: 34, Issue:2 Topics: Acetylcysteine; Animals; Bronchoalveolar Lavage Fluid; Deferoxamine; Disease Models, Animal; Humans; Oxidation-Reduction; Oxidative Stress; Respiratory Distress Syndrome; Sepsis; Siderophores	2006
Attenuation of acute lung injury following lower limb ischemia/reperfusion: the pharmacological approach. The Journal of cardiovascular surgery, 2006, Volume: 47, Issue:4 Topics: Acetylcysteine; Animals; Aprotinin; Biomarkers; Calcium Dobesilate; Creatine Kinase; Disease Models, Animal; Drug Therapy, Combination; Free Radical Scavengers; Hemostatics; L-Lactate Dehydrogenase; Lower Extremity; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Respiratory Distress Syndrome; Thiobarbituric Acid Reactive Substances; Treatment Outcome	2006
Protective effects of N-acetylcysteine and erdosteine on hemorrhagic shock-induced acute lung injury. European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2006, Volume: 13, Issue:5 Topics: Acetylcysteine; Animals; Blood Pressure; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Free Radical Scavengers; Glutathione; Lung; Macrophages, Alveolar; Male; Malondialdehyde; Neutrophils; Premedication; Random Allocation; Rats; Rats, Wistar; Respiratory Distress Syndrome; Shock, Hemorrhagic; Thioglycolates; Thiophenes	2006
Cleistanthus collinus poisoning. The Journal of the Association of Physicians of India, 2006, Volume: 54 Topics: Acetylcysteine; Acidosis, Renal Tubular; Adult; Glycosides; Humans; Hypokalemia; Lignans; Male; Plant Leaves; Plant Poisoning; Plants, Toxic; Respiratory Distress Syndrome; Shock; Toxins, Biological; Treatment Outcome; Vasodilation	2006
Genetic and pharmacologic evidence links oxidative stress to ventilator-induced lung injury in mice. American journal of respiratory and critical care medicine, 2007, Dec-15, Volume: 176, Issue:12 Topics: Acetylcysteine; Animals; Antioxidants; Capillary Permeability; Cytokines; Disease Models, Animal; Free Radical Scavengers; Inflammation; Male; Mice; Mice, Knockout; NF-E2-Related Factor 2; Oxidative Stress; Respiratory Distress Syndrome; Ventilators, Mechanical	2007
N-acetylcysteine attenuates acute lung injury induced by fat embolism. Critical care medicine, 2008, Volume: 36, Issue:2 Topics: Acetylcysteine; Animals; Embolism, Fat; Expectorants; Leukocyte Elastase; Male; Nitric Oxide Synthase Type II; Peroxidase; Pulmonary Embolism; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome	2008
N-acetylcysteine as the magic bullet: too good to be true. Critical care medicine, 2008, Volume: 36, Issue:2 Topics: Acetylcysteine; Animals; Disease Models, Animal; Embolism, Fat; Expectorants; Humans; Pulmonary Embolism; Respiratory Distress Syndrome	2008
Ability of antioxidant liposomes to prevent acute and progressive pulmonary injury. Antioxidants & redox signaling, 2008, Volume: 10, Issue:5 Topics: Acetylcysteine; Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Chemokines; Cytokines; Free Radical Scavengers; Humans; Liposomes; Lung; Macrophages, Alveolar; Male; Mustard Gas; Rats; Rats, Long-Evans; Respiratory Distress Syndrome; Tocopherols	2008
Oxidant stress mediates inflammation and apoptosis in ventilator-induced lung injury. Respirology (Carlton, Vic.), 2008, Volume: 13, Issue:3 Topics: Acetylcysteine; Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Chemokine CXCL2; Disease Models, Animal; Epithelial Cells; Free Radical Scavengers; Glutathione; Interleukin-6; Lung; Oxidative Stress; Pneumonia; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Tumor Necrosis Factor-alpha; Ventilators, Mechanical	2008
Postinsult treatment with N-acetyl-L-cysteine decreases IL-1-induced neutrophil influx and lung leak in rats. The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 1 Topics: Acetylcysteine; Animals; Disease Models, Animal; Glutathione; Glutathione Disulfide; Humans; Hydrogen Peroxide; Interleukin-1; Lung; Male; Neutrophils; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Respiration; Respiratory Distress Syndrome	1993
[N-acetylcysteine decreases functional and structural, ARDS-typical lung changes in endotoxin-treated rats]. Medizinische Klinik (Munich, Germany : 1983), 1993, Apr-15, Volume: 88, Issue:4 Topics: Acetylcysteine; Animals; Endotoxins; Lung; Perfusion; Rats; Reactive Oxygen Species; Respiratory Distress Syndrome; Salmonella enteritidis; Ventilation-Perfusion Ratio	1993
In vivo antioxidant treatment suppresses nuclear factor-kappa B activation and neutrophilic lung inflammation. Journal of immunology (Baltimore, Md. : 1950), 1996, Aug-15, Volume: 157, Issue:4 Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Base Sequence; Chemokines, CXC; Chemotactic Factors; Chemotaxis, Leukocyte; Dinoprost; Disease Models, Animal; Drug Evaluation, Preclinical; Endotoxins; F2-Isoprostanes; Gene Expression Regulation; Glutathione; Growth Substances; Inflammation; Intercellular Signaling Peptides and Proteins; Leukocyte Count; Lung; Lung Diseases; Male; Molecular Sequence Data; Neutrophils; NF-kappa B; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; RNA, Messenger; Sepsis	1996
[Acute respiratory insufficiency after inhaling concrete dust--a case report]. Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1997, Volume: 32, Issue:1 Topics: Acetylcysteine; Bronchoalveolar Lavage; Bronchoscopy; Construction Materials; Dust; Humans; Male; Middle Aged; Oxygen Inhalation Therapy; Radiography; Respiratory Distress Syndrome	1997
Activation of polymorphonuclear leukocytes in oleic acid-induced lung injury. Intensive care medicine, 1998, Volume: 24, Issue:7 Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Animals; Capillary Permeability; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Free Radical Scavengers; Guinea Pigs; Leukocyte Elastase; Male; Neutrophils; Oleic Acid; Prospective Studies; Pulmonary Circulation; Rats; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Superoxides	1998
Reactive oxygen species in acute lung injury. The European respiratory journal, 1998, Volume: 12, Issue:6 Topics: Acetylcysteine; Antioxidants; Humans; Reactive Oxygen Species; Respiratory Distress Syndrome	1998
Priming for enhanced alveolar fibrin deposition after hemorrhagic shock: role of tumor necrosis factor. American journal of respiratory cell and molecular biology, 2000, Volume: 22, Issue:4 Topics: Acetylcysteine; Animals; Antioxidants; Blood Coagulation Disorders; Bronchoalveolar Lavage Fluid; Capillary Leak Syndrome; Disseminated Intravascular Coagulation; Fibrin; Fibrinolysis; Gene Expression Regulation; Lipopolysaccharides; Lipoproteins; Macrophage Activation; Macrophages, Alveolar; Male; Models, Biological; Neutrophils; NF-kappa B; Oxidative Stress; Plasminogen Activator Inhibitor 1; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Respiratory Distress Syndrome; Shock, Hemorrhagic; Shock, Septic; Thromboplastin; Transcription, Genetic; Tumor Necrosis Factor-alpha	2000
Oxidatively modified proteins in bronchoalveolar lavage fluid of patients with ARDS and patients at-risk for ARDS. The European respiratory journal, 1999, Volume: 13, Issue:1 Topics: Acetylcysteine; Adult; Aged; Bronchoalveolar Lavage Fluid; Female; Humans; Male; Methylprednisolone; Middle Aged; Oxidation-Reduction; Proteins; Reactive Oxygen Species; Respiratory Distress Syndrome; Risk Factors	1999
Liposomal antioxidants provide prolonged protection against acute respiratory distress syndrome. Surgery, 2000, Volume: 128, Issue:2 Topics: Acetylcysteine; Animals; Antioxidants; Chemokines, CXC; Chemotactic Factors; Drug Carriers; Gene Expression Regulation; Growth Substances; Hemorrhage; Injections, Intravenous; Intercellular Signaling Peptides and Proteins; Lipopolysaccharides; Liposomes; Lung; Male; Neutrophils; Peroxidase; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Resuscitation	2000
N-acetyl-L-cysteine inhibits bleomycin-induced interleukin-8 secretion by bronchial epithelial cells. Respirology (Carlton, Vic.), 2000, Volume: 5, Issue:4 Topics: Acetylcysteine; Antimetabolites, Antineoplastic; Antioxidants; Bleomycin; Bronchi; Cell Line; Drug Evaluation, Preclinical; Enzyme-Linked Immunosorbent Assay; Free Radical Scavengers; Humans; Interleukin-8; Pyrrolidines; Respiratory Distress Syndrome; Respiratory Mucosa; Thiocarbamates	2000
Intracellular antioxidant activity is necessary to modulate the macrophage response to endotoxin. Shock (Augusta, Ga.), 2002, Volume: 18, Issue:1 Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Blood Coagulation Factors; Butylated Hydroxyanisole; Cells, Cultured; Chromans; Endotoxins; F2-Isoprostanes; Inflammation; Macrophages, Alveolar; Male; Rabbits; Reactive Oxygen Species; Respiratory Distress Syndrome; Signal Transduction; Superoxide Dismutase; Tumor Necrosis Factor-alpha	2002
Protection against pulmonary O2 toxicity by N-acetylcysteine. The European respiratory journal, 1989, Volume: 2, Issue:2 Topics: Acetylcysteine; Administration, Oral; Animals; Antioxidants; Dogs; Free Radicals; Glutathione; Lung Diseases; Oxygen; Respiratory Distress Syndrome; Respiratory Function Tests	1989
Acetylcysteine to treat complications of pancreatitis. Lancet (London, England), 1986, Apr-19, Volume: 1, Issue:8486 Topics: Acetylcysteine; Acute Disease; Humans; Male; Middle Aged; Pancreatitis; Respiratory Distress Syndrome	1986
Effect of N-acetylcysteine on pulmonary damage due to microembolism in the rat. European journal of respiratory diseases, 1987, Volume: 70, Issue:4 Topics: Acetylcysteine; Animals; Blood Viscosity; Male; Pulmonary Embolism; Rats; Rats, Inbred Strains; Respiratory Distress Syndrome	1987