acetylcysteine has been researched along with Prostatic Neoplasms in 63 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.59) | 18.7374 |
| 1990's | 4 (6.35) | 18.2507 |
| 2000's | 19 (30.16) | 29.6817 |
| 2010's | 34 (53.97) | 24.3611 |
| 2020's | 5 (7.94) | 2.80 |
| Authors | Studies |
|---|---|
| Choung, DH; Han, DC; Kim, CH; Kim, YH; Kwon, BM; Lee, S; Lee, YJ; Yoon, YJ | 1 |
| Li, W; Liang, L; Sang, X; Wang, F; Zhang, F | 1 |
| Huang, J; Li, J; Li, Y; Liu, B; Qiu, J; Wang, D; Wu, J; Xie, R; Zhou, J | 1 |
| Li, Z; Long, Y; Luo, G; Shen, W; Shi, X; Zhang, X; Zheng, Z | 1 |
| Hoy, JJ; Iglesias-Bartolome, R; Kuhn, S; Park, J; Salinas Parra, N | 1 |
| Angelillo, IF; Barone, B; Boccellino, M; Boffo, S; Crocetto, F; Di Domenico, M; Di Zazzo, E; Galasso, G; Imbimbo, C; Quagliuolo, L; Sciarra, A; Settembre, G | 1 |
| Awasthi, S; Horne, D; Jain, D; Singhal, J; Singhal, P; Singhal, SS | 1 |
| Chen, W; Huang, H; Pan, Y; Xia, Y; Xie, H; Zheng, K | 1 |
| Karnewar, S; Kotamraju, S; Mallappa, S; Neeli, PK | 1 |
| Damodaran, C; Das, TP; Suman, S | 1 |
| Huh, YJ; Park, JW; Yang, ES | 1 |
| Supabphol, A; Supabphol, R | 1 |
| Ernst, E; Ko, BS; Lee, HW; Lee, MS; Onakpoya, I; Posadzki, P | 1 |
| Lee, DM; Lee, SH; Lee, YJ | 1 |
| Elhilali, MM; Elmansy, HM; Elshal, AM | 1 |
| Haidari, M; Wakame, K; Zhang, W | 1 |
| Cho, KH; Choi, MJ; Hwang, MH; Jeong, KJ; Kim, JJ; Lee, HY; Park, CG; Shin, SC | 1 |
| Frank, SJ; Ibbott, G; Kudchadker, RJ; Lim, TY; Martirosyan, KS; Rao, A; Sankaranarayanapillai, M; Stafford, RJ | 1 |
| Basu, HS; Beebe, DJ; Bischel, LL; Casavant, BP; Eliceiri, KW; Young, PA | 1 |
| Huang, S; Huang, W; Huang, X; Huang, Y; Li, Y; Pei, C; Pu, H; Wan, X; Wu, H; Yang, S; Zhang, C; Zhang, J; Zhang, Y | 1 |
| Chang, JL; Cheng, CW; Chien, MH; Chow, JM; Hsiao, M; Lai, GM; Lee, LM; Lee, WJ; Lin, YW; Wen, YC | 1 |
| Han, X; Li, B; Li, C; Wu, J; Zhang, H | 1 |
| Bjartell, A; Canesin, G; Escobar, Z; Evans-Axelsson, S; Hellsten, R; Johansson, MH; Sterner, O | 1 |
| Gao, HW; He, YY; Khan, M; Li, YM; Ma, TH; Yang, JB; Yao, M | 1 |
| Gong, A; He, M; Karnes, RJ; Krishna Vanaja, D; Yin, P; Young, CY | 1 |
| Bryskin, I; Hou, ZF; Lu, JP; Monardo, L; Pinthus, JH; Trachtenberg, J; Wilson, BC | 1 |
| Eto, M; Inokuchi, J; Kashiwagi, E; Masubuchi, D; Naito, S; Shiota, M; Tada, Y; Uchiumi, T; Yokomizo, A | 1 |
| Cheng, L; Crooks, P; Kusumanchi, P; Matthews, W; Nakshatri, H; Neelakantan, S; Shanmugam, R; Sweeney, CJ | 1 |
| Hwang, ES; Lee, HJ | 1 |
| Cho, MK; Heo, SH; Im, JH; Lee, CH; Lee, DM; Lee, SH; Lee, YJ; Nam, HS; Won, SY | 1 |
| Chiu, TH; Chueh, FS; Chung, JG; Huang, YT; Ji, BC; Liu, KC; Wu, PP; Yang, JL; Yang, JS | 1 |
| Chang, FR; Chen, HM; Cheng, YJ; Hsieh, KC; Hsieh, YC; Lin, AS; Tsai, LM; Wu, YC; Yuan, SS | 1 |
| Naito, S; Shiota, M; Yokomizo, A | 1 |
| Al-Husein, B; Al-Shabrawey, M; Bollag, WB; Choudhary, V; Davis, M; Dong, Z; El Gaish, M; Kaddour-Djebbar, I; Kumar, MV; Lakshmikanthan, V; Shirley, R; Zhong, R | 1 |
| Agharahimi, M; Badisa, RB; Goodman, CB; Mazzio, E; Oriaku, ET; Russell, LH; Zhu, ZP | 1 |
| Ehrlich, M; Pinkas-Kramarski, R; Schmukler, E; Shai, B | 1 |
| Aghazarian, M; Cucchi, S; Galmarini, F; Goldschmidt, P; Golomar, W; Gordon, W; Lasalvia-Galante, E; Lasalvia-Prisco, E; Vázquez, J | 1 |
| Alapinar, C; Debelec-Butuner, B; Erbaykent-Tepedelen, B; Gonen-Korkmaz, C; Hamid, SM; Korkmaz, KS; Varisli, L | 1 |
| Borne, A; Carmazzi, Y; Frank, SJ; Gagea, M; Johansen, MJ; Madden, T; Martirosyan, KS; Van Pelt, CS | 1 |
| Choi, BT; Choi, YH; Jeong, JW; Jeong, YK; Kang, BW; Kim, GY; Kim, MJ; Lee, HH; Park, C; Park, JU; Seo, MJ | 1 |
| Caplan, AJ; Cardozo, CP; Fliss, AE; Hall, SJ; Michaud, C; Ost, MC; Patterson, C; Yang, E | 1 |
| Chiao, JW; Chung, FL; Conaway, CC; Liu, D; Ramaswamy, G; Wang, L; Wu, H | 1 |
| Johnson, CS; Singh, SV; Trump, DL; Xiao, D | 1 |
| Beckett, MA; Hellman, S; Kimchi, ET; Kufe, DW; Lopez, CA; Mauceri, HJ; Mehta, N; Murphy, KT; Park, JO; Posner, MC; Weichselbaum, RR | 1 |
| Antosiewicz, J; Choi, S; Herman-Antosiewicz, A; Johnson, CS; Lee, YJ; Lew, KL; Singh, SV; Srivastava, SK; Trump, DL; Watkins, SC; Xiao, D; Xiao, H; Zeng, Y | 1 |
| Kaddour-Djebbar, I; Kumar, MV; Lakshmikanthan, V; Lewis, RW; Patel, DM; Shirley, RB | 1 |
| Agarwal, C; Agarwal, R; Kaur, M | 1 |
| Bhattacharyya, RS; Feldman, D; Husbeck, B; Knox, SJ | 1 |
| Hu, H; Jiang, C; Li, GX; Lü, J; Schuster, T | 1 |
| Kim, YA; Lew, KL; Powolny, AA; Reilly, ML; Singh, SV; Wang, Z; Xiao, D; Xiao, H; Zeng, Y | 1 |
| Balaji, KC; Du, C; Narayani, N; Zhang, C; Zhang, W | 1 |
| Hahm, ER; Singh, SV | 1 |
| Powolny, AA; Singh, SV | 1 |
| Gorospe, M; Kawai, T; Otto, K; Rinker-Schaeffer, CW; Robinson, VL; Shalhav, O | 1 |
| Gupta, S; Shukla, S | 1 |
| Baraban, JM; Hardwick, JM; Lee, SH; Lin, KI; Narayanan, R; Ratan, RR | 1 |
| Choi, YH; Henkart, PA; Jang, JS; Lee, J; Lee, SJ; Maki, M; Nguyen, P; Takano, E; Trepel, JB; Wu, ML | 1 |
| Chung, LW; Li, H; Sang, QA; Schwartz, MA; Zhau, HE | 1 |
| Choi, YH; Jang, JS | 1 |
| Hescheler, J; Klimm, B; Sauer, H; Wartenberg, M | 1 |
| Hayashi, Y; Kawai, N; Kohri, K; Okamoto, T; Sasaki, S; Tozawa, K | 1 |
| Choudhury, MS; Davidson, SD; Konno, S; Mallouh, C; Milanesa, DM; Tazaki, H | 1 |
| Berra, S; Galli, L | 1 |
4 review(s) available for acetylcysteine and Prostatic Neoplasms
| Article | Year |
|---|---|
The Crosstalk between Prostate Cancer and Microbiota Inflammation: Nutraceutical Products Are Useful to Balance This Interplay?
Topics: Acetylcysteine; Carnitine; Chronic Disease; Dietary Supplements; Disease Progression; Fatty Acids, Unsaturated; Gastrointestinal Microbiome; Humans; Inflammation; Male; Monoterpenes; Polyphenols; Prostate; Prostatic Neoplasms | 2020 |
Targeting the mercapturic acid pathway and vicenin-2 for prevention of prostate cancer.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Apigenin; Docetaxel; Drug Resistance, Neoplasm; Glucosides; Humans; Male; Prostatic Neoplasms; Signal Transduction; Taxoids | 2017 |
Dietary supplements and prostate cancer: a systematic review of double-blind, placebo-controlled randomised clinical trials.
Topics: Acetylcysteine; Antioxidants; Dietary Supplements; Humans; Male; Minerals; Plant Extracts; Prostate-Specific Antigen; Prostatic Neoplasms; Trace Elements; Vitamins | 2013 |
Oxidative stress and androgen receptor signaling in the development and progression of castration-resistant prostate cancer.
Topics: Acetylcysteine; Androgen Antagonists; Androgens; Animals; Antioxidants; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cytokines; Disease Progression; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Intercellular Signaling Peptides and Proteins; Male; Mice; Mutation; Orchiectomy; Oxidative Stress; Prostate; Prostatic Neoplasms; Protein Isoforms; Receptors, Androgen; Signal Transduction | 2011 |
2 trial(s) available for acetylcysteine and Prostatic Neoplasms
| Article | Year |
|---|---|
Two laser ablation techniques for a prostate less than 60 mL: lessons learned 70 months after a randomized controlled trial.
Topics: Acetylcysteine; Adenoma; Aged; Aged, 80 and over; Contracture; Humans; Laser Therapy; Lasers, Solid-State; Length of Stay; Male; Middle Aged; Organ Size; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Prostatism; Quality of Life; Reoperation; Single-Blind Method; Urethral Stricture; Urinary Bladder Neck Obstruction | 2013 |
Addition of an induction regimen of antiangiogenesis and antitumor immunity to standard chemotherapy improves survival in advanced malignancies.
Topics: Acetylcysteine; Angiogenesis Inhibitors; Antigens, Neoplasm; Antineoplastic Agents; Carcinoma; Carcinoma, Non-Small-Cell Lung; Celecoxib; Cyclophosphamide; Female; Humans; Immunization; Immunotherapy; Induction Chemotherapy; Kaplan-Meier Estimate; Male; Pancreatic Neoplasms; Prostatic Neoplasms; Pyrazoles; Sulfonamides | 2012 |
57 other study(ies) available for acetylcysteine and Prostatic Neoplasms
| Article | Year |
|---|---|
Piperlongumine derivative, CG-06, inhibits STAT3 activity by direct binding to STAT3 and regulating the reactive oxygen species in DU145 prostate carcinoma cells.
Topics: Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Proliferation; Dioxolanes; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Interleukin-6; Male; Molecular Structure; Phosphorylation; Prostatic Neoplasms; Reactive Oxygen Species; STAT3 Transcription Factor; Structure-Activity Relationship | 2018 |
The toxicity mechanism of glabridin in prostate cancer cells is involved in reactive oxygen species-dependent PI3K/Akt pathway: Integrated utilization of bioinformatic analysis and in vitro test validation.
Topics: Acetylcysteine; Apoptosis; Caspase 3; Cell Proliferation; Computational Biology; Humans; In Vitro Techniques; Male; Phosphatidylinositol 3-Kinases; Prospective Studies; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species | 2022 |
Gambogenic acid induces apoptosis and autophagy through ROS-mediated endoplasmic reticulum stress via JNK pathway in prostate cancer cells.
Topics: Acetylcysteine; Apoptosis; Autophagy; Cell Line, Tumor; Endoplasmic Reticulum Stress; Humans; Male; MAP Kinase Signaling System; Prostatic Neoplasms; Reactive Oxygen Species | 2023 |
The X
Topics: Acetylcysteine; Amino Acid Transport System y+; Animals; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Ascorbic Acid; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; Glutathione; Humans; Immunohistochemistry; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Prostatic Neoplasms; Reactive Oxygen Species; Sulfasalazine; Transplantation, Heterologous | 2020 |
Protein kinase A inhibitor proteins (PKIs) divert GPCR-Gαs-cAMP signaling toward EPAC and ERK activation and are involved in tumor growth.
Topics: Acetylcysteine; Animals; Cell Line, Tumor; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Erythromycin; Extracellular Signal-Regulated MAP Kinases; Feedback, Physiological; Female; GTP-Binding Protein alpha Subunits; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Male; MAP Kinase Signaling System; Mice; Mice, Nude; Prostatic Neoplasms | 2020 |
Plumbagin Triggers ER Stress-Mediated Apoptosis in Prostate Cancer Cells via Induction of ROS.
Topics: Acetylcysteine; Activating Transcription Factor 4; Animals; Apoptosis; Caspase 3; Caspase 9; Cell Line, Tumor; eIF-2 Kinase; Endoplasmic Reticulum Stress; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Naphthoquinones; Prostatic Neoplasms; Reactive Oxygen Species; RNA Interference; Transcription Factor CHOP; Transplantation, Heterologous | 2018 |
Doxorubicin induces prostate cancer drug resistance by upregulation of ABCG4 through GSH depletion and CREB activation: Relevance of statins in chemosensitization.
Topics: Acetylcysteine; Animals; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily G; Cyclic AMP Response Element-Binding Protein; Doxorubicin; Drug Resistance, Neoplasm; Glutathione; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mice; Mice, Nude; Prostatic Neoplasms; RNA Interference; RNA, Small Interfering; Simvastatin; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2019 |
Induction of reactive oxygen species generation inhibits epithelial-mesenchymal transition and promotes growth arrest in prostate cancer cells.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Benzofurans; beta Catenin; Cadherins; Caspase 3; Caspase 9; Catalase; Cell Line, Tumor; Cell Movement; Cell Proliferation; Coumarins; Cytochromes c; Enzyme Activation; Epithelial-Mesenchymal Transition; Humans; Male; Membrane Potential, Mitochondrial; Neoplasm Invasiveness; Oxidative Stress; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; Reactive Oxygen Species; Snail Family Transcription Factors; Superoxide Dismutase; Superoxide Dismutase-1; Transcription Factors; Transcription, Genetic | 2014 |
RNA interference targeting sensitive-to-apoptosis gene potentiates doxorubicin- and staurosporine-induced apoptosis of PC3 cells.
Topics: Acetylcysteine; Apoptosis; Cell Line, Tumor; Doxorubicin; Humans; Male; Prostatic Neoplasms; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Staurosporine; Ubiquitin-Protein Ligases | 2013 |
Antimetastatic potential of N-acetylcysteine on human prostate cancer cells.
Topics: Acetylcysteine; Adenocarcinoma; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Free Radical Scavengers; Humans; Male; Neoplasm Invasiveness; Prostatic Neoplasms | 2012 |
Production of Cyr61 protein is modulated by extracellular acidification and PI3K/Akt signaling in prostate carcinoma PC-3 cells.
Topics: Acetylcysteine; Acids; Apoptosis; Cell Line, Tumor; Cysteine-Rich Protein 61; Gene Silencing; Humans; Male; Phosphatidylinositol 3-Kinases; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Signal Transduction; Up-Regulation | 2013 |
Disruption of endothelial adherens junction by invasive breast cancer cells is mediated by reactive oxygen species and is attenuated by AHCC.
Topics: Acetylcysteine; Adherens Junctions; Antigens, CD; Antineoplastic Agents, Phytogenic; Antioxidants; beta Catenin; Breast Neoplasms; Cadherins; Cell Movement; Endothelial Cells; Endothelium, Vascular; Female; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Male; Ovarian Neoplasms; Plant Extracts; Prostatic Neoplasms; Reactive Oxygen Species; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 2013 |
A ROS/STAT3/HIF-1α signaling cascade mediates EGF-induced TWIST1 expression and prostate cancer cell invasion.
Topics: Acetylcysteine; Cadherins; Cell Line, Tumor; Cell Movement; Disease Progression; Epidermal Growth Factor; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Neoplasm Invasiveness; Nuclear Proteins; Phosphorylation; Prostatic Neoplasms; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction; STAT3 Transcription Factor; Twist-Related Protein 1 | 2014 |
MRI characterization of cobalt dichloride-N-acetyl cysteine (C4) contrast agent marker for prostate brachytherapy.
Topics: Acetylcysteine; Brachytherapy; Contrast Media; Fiducial Markers; Humans; Magnetic Resonance Imaging; Male; Prostatic Neoplasms; Temperature; Time Factors | 2014 |
A microfluidic coculture and multiphoton FAD analysis assay provides insight into the influence of the bone microenvironment on prostate cancer cells.
Topics: Acetylcysteine; Cell Line, Tumor; Coculture Techniques; Flavin-Adenine Dinucleotide; Humans; Male; Mesenchymal Stem Cells; Microfluidics; Microscopy, Fluorescence, Multiphoton; Prostatic Neoplasms; Reactive Oxygen Species | 2014 |
KDM1A triggers androgen-induced miRNA transcription via H3K4me2 demethylation and DNA oxidation.
Topics: Acetylcysteine; Cell Line, Tumor; DNA, Neoplasm; Histone Demethylases; Histones; Humans; Kallikreins; Male; MicroRNAs; Neoplasms, Hormone-Dependent; Oxidation-Reduction; Pargyline; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Small Interfering; Serine Endopeptidases; Transcription, Genetic | 2015 |
Nonautophagic cytoplasmic vacuolation death induction in human PC-3M prostate cancer by curcumin through reactive oxygen species -mediated endoplasmic reticulum stress.
Topics: Acetylcysteine; Animals; Apoptosis; Cell Line, Tumor; Cell Survival; Curcumin; Cycloheximide; Disease Models, Animal; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Heat-Shock Proteins; Humans; Immunohistochemistry; Male; Mice; Mice, SCID; Microtubule-Associated Proteins; Prostatic Neoplasms; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Transcription Factor CHOP; Transplantation, Heterologous; Vacuoles | 2015 |
The interplay between autophagy and apoptosis induced by tanshinone IIA in prostate cancer cells.
Topics: Abietanes; Acetylcysteine; Adenocarcinoma; Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Beclin-1; Caspase 3; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Male; Microtubule-Associated Proteins; Neoplasm Proteins; Prostatic Neoplasms; Reactive Oxygen Species | 2016 |
Preclinical Characterization of 3β-(N-Acetyl l-cysteine methyl ester)-2aβ,3-dihydrogaliellalactone (GPA512), a Prodrug of a Direct STAT3 Inhibitor for the Treatment of Prostate Cancer.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Male; Mice; Mice, Nude; Models, Molecular; Molecular Structure; Neoplasms, Experimental; Prodrugs; Prostatic Neoplasms; STAT3 Transcription Factor; Structure-Activity Relationship; Tumor Cells, Cultured | 2016 |
Tubeimoside-1 induces oxidative stress-mediated apoptosis and G0/G1 phase arrest in human prostate carcinoma cells in vitro.
Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Anthracenes; Apoptosis; Caspase 3; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Cinnamates; Cyclin E; Cyclin-Dependent Kinase 2; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; G1 Phase; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase Kinase 5; Membrane Potential, Mitochondrial; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Pyridines; Reactive Oxygen Species; Resting Phase, Cell Cycle; Saponins; Thiourea; Triterpenes | 2016 |
Phenethyl isothiocyanate inhibits STAT3 activation in prostate cancer cells.
Topics: Acetylcysteine; Anticarcinogenic Agents; Cell Division; Cell Line, Tumor; Cell Proliferation; G2 Phase; Humans; Interleukin-6; Isothiocyanates; Janus Kinase 2; Male; Phosphorylation; Prostatic Neoplasms; Receptors, Androgen; STAT3 Transcription Factor | 2009 |
Androgens induce oxidative stress and radiation resistance in prostate cancer cells though NADPH oxidase.
Topics: Acetophenones; Acetylcysteine; Androgen Antagonists; Androgens; Anilides; Animals; Cell Line, Tumor; Humans; Male; Membrane Glycoproteins; Metribolone; Mice; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Neoplasm Transplantation; Nitriles; Onium Compounds; Oxidative Stress; Prostatic Neoplasms; Radiation-Sensitizing Agents; Reactive Oxygen Species; Tosyl Compounds | 2010 |
Castration resistance of prostate cancer cells caused by castration-induced oxidative stress through Twist1 and androgen receptor overexpression.
Topics: Acetylcysteine; Apoptosis; Binding Sites; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Free Radical Scavengers; G1 Phase; Gene Expression Regulation, Neoplastic; Humans; Hydrogen Peroxide; Male; Nuclear Proteins; Orchiectomy; Oxidants; Oxidative Stress; Promoter Regions, Genetic; Prostatic Neoplasms; Protein Binding; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Twist-Related Protein 1 | 2010 |
A water-soluble parthenolide analogue suppresses in vivo prostate cancer growth by targeting NFkappaB and generating reactive oxygen species.
Topics: Acetylcysteine; Animals; Apoptosis; Cell Growth Processes; Cell Line, Tumor; Electrophoretic Mobility Shift Assay; Enzyme Activation; Female; Humans; Immunohistochemistry; Male; Mice; Mice, Nude; Mitogen-Activated Protein Kinase 9; NF-kappa B; Prostatic Neoplasms; Reactive Oxygen Species; Sesquiterpenes; Specific Pathogen-Free Organisms | 2010 |
Effects of phenylethyl isothiocyanate and its metabolite on cell-cycle arrest and apoptosis in LNCaP human prostate cancer cells.
Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Apoptosis; Brassicaceae; CDC2 Protein Kinase; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin B1; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression; Glucosinolates; Humans; Isothiocyanates; Male; Phytotherapy; Plant Extracts; Prostatic Neoplasms | 2010 |
Suppression of human prostate cancer PC-3 cell growth by N-acetylcysteine involves over-expression of Cyr61.
Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine-Rich Protein 61; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; I-kappa B Kinase; Male; NF-kappa B; Prostatic Neoplasms; Protein Synthesis Inhibitors; Reactive Oxygen Species; RNA, Messenger; Signal Transduction; Up-Regulation | 2011 |
The roles of AIF and Endo G in the apoptotic effects of benzyl isothiocyanate on DU 145 human prostate cancer cells via the mitochondrial signaling pathway.
Topics: Acetylcysteine; Adenocarcinoma; Antineoplastic Agents; Apoptosis; Apoptosis Inducing Factor; Caspases; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Endodeoxyribonucleases; Gene Expression Regulation, Neoplastic; Humans; Isothiocyanates; Male; Membrane Potential, Mitochondrial; Mitochondria; Models, Biological; Prostatic Neoplasms; Signal Transduction | 2011 |
A novel synthetic protoapigenone analogue, WYC02-9, induces DNA damage and apoptosis in DU145 prostate cancer cells through generation of reactive oxygen species.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 9; Cell Cycle; Cell Line, Tumor; Checkpoint Kinase 1; Checkpoint Kinase 2; Cyclohexanones; DNA Damage; Flavones; Gene Expression; Histones; Humans; Male; Membrane Potential, Mitochondrial; Mice; Mice, Nude; Mitochondria; Neoplasm Transplantation; Neoplasms, Experimental; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; Protein Kinases; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Tumor Suppressor Protein p53 | 2011 |
Diltiazem enhances the apoptotic effects of proteasome inhibitors to induce prostate cancer cell death.
Topics: Acetylcysteine; Apoptosis; Blotting, Western; Boronic Acids; Bortezomib; Calcium; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Endoplasmic Reticulum Chaperone BiP; Humans; Male; Prostatic Neoplasms; Protease Inhibitors; Pyrazines; Transfection; Tumor Cells, Cultured | 2012 |
Autoxidation of gallic acid induces ROS-dependent death in human prostate cancer LNCaP cells.
Topics: Acetylcysteine; Apoptosis; Caspases; Cell Line, Tumor; Cytochromes c; Gallic Acid; Glutathione; Humans; Male; Membrane Potential, Mitochondrial; Oxidation-Reduction; Prostatic Neoplasms; Reactive Oxygen Species | 2012 |
Neuregulin promotes incomplete autophagy of prostate cancer cells that is independent of mTOR pathway inhibition.
Topics: Acetylcysteine; Adenine; Anthracenes; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Cell Death; Cell Line, Tumor; Humans; Male; MAP Kinase Signaling System; Membrane Proteins; Neoplasms, Hormone-Dependent; Neuregulins; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Recombinant Proteins; Signal Transduction; TOR Serine-Threonine Kinases | 2012 |
Inflammation-mediated abrogation of androgen signaling: an in vitro model of prostate cell inflammation.
Topics: Acetylcysteine; Androgens; Antioxidants; Apoptosis; Cell Differentiation; Cell Line, Tumor; Down-Regulation; Glutathione Peroxidase; Homeodomain Proteins; Humans; I-kappa B Proteins; Inflammation; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Kallikreins; Lysine; Macrophages; Male; Matrix Metalloproteinase 9; NF-kappa B; Phosphorylation; Prostate-Specific Antigen; Prostatic Neoplasms; Prostatitis; Proto-Oncogene Proteins c-mdm2; Reactive Oxygen Species; Receptors, Androgen; Signal Transduction; Transcription Factors; Transcriptional Activation; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; U937 Cells; Up-Regulation | 2014 |
A biodistribution and toxicity study of cobalt dichloride-N-acetyl cysteine in an implantable MRI marker for prostate cancer treatment.
Topics: Acetylcysteine; Animals; Brachytherapy; Humans; Kidney; Liver; Magnetic Resonance Imaging; Male; Prostate; Prostatic Neoplasms; Rats; Tissue Distribution | 2013 |
Apoptosis induction of human prostate carcinoma cells by cordycepin through reactive oxygen species‑mediated mitochondrial death pathway.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Cytochromes c; Deoxyadenosines; Down-Regulation; Enzyme Activation; Humans; Inhibitor of Apoptosis Proteins; Male; Membrane Potential, Mitochondrial; Mitochondria; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species | 2013 |
C-terminal Hsp-interacting protein slows androgen receptor synthesis and reduces its rate of degradation.
Topics: Acetylcysteine; Benzoquinones; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dihydrotestosterone; Gene Expression; HeLa Cells; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Leupeptins; Ligases; Male; Molecular Chaperones; Multienzyme Complexes; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Quinones; Receptors, Androgen; Receptors, Estrogen; Receptors, Glucocorticoid; Tumor Cells, Cultured; Ubiquitin; Ubiquitin-Protein Ligases | 2003 |
Ingestion of an isothiocyanate metabolite from cruciferous vegetables inhibits growth of human prostate cancer cell xenografts by apoptosis and cell cycle arrest.
Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Bromodeoxyuridine; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Cell Separation; Coloring Agents; Cyclin D; Cyclin E; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Flow Cytometry; G1 Phase; Humans; Isothiocyanates; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitosis; Neoplasm Transplantation; Neoplasms; Phosphorylation; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; S Phase; Time Factors; Tumor Suppressor Proteins; Up-Regulation; Vegetables | 2004 |
Proteasome-mediated degradation of cell division cycle 25C and cyclin-dependent kinase 1 in phenethyl isothiocyanate-induced G2-M-phase cell cycle arrest in PC-3 human prostate cancer cells.
Topics: Acetylcysteine; Anticarcinogenic Agents; Apoptosis; bcl-X Protein; Caspases; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine Proteinase Inhibitors; G2 Phase; Gene Expression Regulation; Humans; Isothiocyanates; Male; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-bcl-2; Transfection | 2004 |
Chemoinducible gene therapy: a strategy to enhance doxorubicin antitumor activity.
Topics: Acetylcysteine; Adenoviridae; Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Combined Modality Therapy; DNA-Binding Proteins; Doxorubicin; Drug Resistance, Neoplasm; Early Growth Response Protein 1; Genetic Therapy; Genetic Vectors; Humans; Immediate-Early Proteins; Male; Neoplasms; Neovascularization, Pathologic; Promoter Regions, Genetic; Prostatic Neoplasms; Rats; Transcription Factors; Tumor Necrosis Factor-alpha; Up-Regulation; Xenograft Model Antitumor Assays | 2004 |
Sulforaphane-induced cell death in human prostate cancer cells is initiated by reactive oxygen species.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Carrier Proteins; Caspase 8; Caspases; Cell Line, Tumor; Cells, Cultured; Cytochromes c; Enzyme Activation; Humans; Isothiocyanates; Male; Membrane Potentials; Mice; Mice, Knockout; Mitochondria; Models, Biological; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Sulfoxides; Thiocyanates | 2005 |
Combination of proteasomal inhibitors lactacystin and MG132 induced synergistic apoptosis in prostate cancer cells.
Topics: Acetylcysteine; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cysteine Proteinase Inhibitors; Drug Synergism; Humans; I-kappa B Kinase; Leupeptins; Male; NF-kappa B; Prostatic Neoplasms; Proteasome Inhibitors; Tumor Cells, Cultured | 2005 |
Grape seed extract induces anoikis and caspase-mediated apoptosis in human prostate carcinoma LNCaP cells: possible role of ataxia telangiectasia mutated-p53 activation.
Topics: Acetylcysteine; Anoikis; Anticarcinogenic Agents; Apoptosis; Apoptosis Inducing Factor; Ataxia Telangiectasia Mutated Proteins; Caspases; Cell Cycle Proteins; Checkpoint Kinase 2; Cytochromes c; DNA-Binding Proteins; Focal Adhesion Kinase 1; Histones; Humans; Male; Plant Extracts; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2006 |
Inhibition of androgen receptor signaling by selenite and methylseleninic acid in prostate cancer cells: two distinct mechanisms of action.
Topics: Acetylcysteine; Androgen Receptor Antagonists; Dose-Response Relationship, Drug; Down-Regulation; Glutathione; Humans; Male; Metalloporphyrins; Metribolone; Organoselenium Compounds; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Receptors, Steroid; Signal Transduction; Sodium Selenite; Sp1 Transcription Factor; Superoxides; Tumor Cells, Cultured | 2006 |
Differential involvement of reactive oxygen species in apoptosis induced by two classes of selenium compounds in human prostate cancer cells.
Topics: Acetylcysteine; Androgens; Antioxidants; Apoptosis; Caspases; Cell Line, Tumor; DNA Breaks; Humans; Male; Organoselenium Compounds; Prostatic Neoplasms; Reactive Oxygen Species; Signal Transduction; Sodium Selenite; Tumor Suppressor Protein p53 | 2007 |
Mitochondria-mediated apoptosis by diallyl trisulfide in human prostate cancer cells is associated with generation of reactive oxygen species and regulated by Bax/Bak.
Topics: Acetylcysteine; Allyl Compounds; Androgens; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Cell Line, Tumor; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Male; Mitochondria; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Sulfides | 2007 |
Nuclear translocation of apoptosis inducing factor is associated with cisplatin induced apoptosis in LNCaP prostate cancer cells.
Topics: Acetylcysteine; Active Transport, Cell Nucleus; Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Apoptosis Inducing Factor; Cell Line, Tumor; Cell Survival; Cisplatin; DNA Fragmentation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Male; Prostatic Neoplasms | 2007 |
Honokiol causes G0-G1 phase cell cycle arrest in human prostate cancer cells in association with suppression of retinoblastoma protein level/phosphorylation and inhibition of E2F1 transcriptional activity.
Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Antioxidants; Biphenyl Compounds; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Drugs, Chinese Herbal; E2F1 Transcription Factor; G1 Phase; Humans; Immunoprecipitation; Lignans; Luciferases; Male; Phosphorylation; Prostatic Neoplasms; Reactive Oxygen Species; Resting Phase, Cell Cycle; Retinoblastoma Protein; RNA, Small Interfering; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2007 |
Plumbagin-induced apoptosis in human prostate cancer cells is associated with modulation of cellular redox status and generation of reactive oxygen species.
Topics: Acetylcysteine; Anticarcinogenic Agents; Antioxidants; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Male; Naphthoquinones; Oxidation-Reduction; Peroxidases; Prostatic Neoplasms; Reactive Oxygen Species; Superoxide Dismutase | 2008 |
Mitogen-activated protein kinase kinase 4/c-Jun NH2-terminal kinase kinase 1 protein expression is subject to translational regulation in prostate cancer cell lines.
Topics: Acetylcysteine; Blotting, Northern; Cell Line, Tumor; Cycloheximide; Dactinomycin; Ethanol; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Male; MAP Kinase Kinase 4; Neoplasm Metastasis; Ovarian Neoplasms; Polymerase Chain Reaction; Prostatic Neoplasms; Protein Biosynthesis | 2008 |
Apigenin-induced prostate cancer cell death is initiated by reactive oxygen species and p53 activation.
Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Antioxidants; Apigenin; Apoptosis; Benzothiazoles; Cell Death; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Humans; Male; Membrane Potential, Mitochondrial; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-mdm2; Reactive Oxygen Species; Signal Transduction; Toluene; Transcription Factor RelA; Tumor Suppressor Protein p14ARF; Tumor Suppressor Protein p53 | 2008 |
Thiol agents and Bcl-2 identify an alphavirus-induced apoptotic pathway that requires activation of the transcription factor NF-kappa B.
Topics: Acetylcysteine; Animals; Apoptosis; Base Sequence; Cell Nucleus; Chelating Agents; Dithiothreitol; DNA; Iron; Lipid Peroxidation; Male; Mercaptoethanol; Mice; Molecular Sequence Data; Neuroblastoma; NF-kappa B; Prostatic Neoplasms; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrrolidines; Rats; Sindbis Virus; Sulfhydryl Reagents; Thiocarbamates; Tumor Cells, Cultured | 1995 |
Regulation of cyclin D1 by calpain protease.
Topics: 3T3 Cells; Acetylcysteine; Animals; Calpain; Cyclin B; Cyclin B1; Cyclin D1; Cysteine Proteinase Inhibitors; Dactinomycin; Half-Life; Humans; Male; Mice; Prostatic Neoplasms; Protein Synthesis Inhibitors; Tumor Cells, Cultured | 1997 |
Targeting matrix metalloproteinases in human prostate cancer.
Topics: Acetylcysteine; Drug Design; Humans; Male; Metalloendopeptidases; Prostatic Neoplasms; Protease Inhibitors; Structure-Activity Relationship; Tumor Cells, Cultured | 1999 |
Proteolytic degradation of the retinoblastoma family protein p107: A putative cooperative role of calpain and proteasome.
Topics: Acetylcysteine; Antineoplastic Agents; Blotting, Western; Calcium-Binding Proteins; Calpain; CDC2-CDC28 Kinases; Cell Cycle; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Cysteine Proteinase Inhibitors; Humans; Lovastatin; Male; Nuclear Proteins; Proliferating Cell Nuclear Antigen; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Retinoblastoma Protein; Retinoblastoma-Like Protein p107; Sarcoma, Ewing; Transfection; Tumor Cells, Cultured; Ubiquitins | 1999 |
Activation of p90RSK and growth stimulation of multicellular tumor spheroids are dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP.
Topics: Acetylcysteine; Adenosine Triphosphate; Calcium; Cell Division; Dose-Response Relationship, Drug; Enzyme Activation; Flavonoids; Free Radical Scavengers; Humans; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; NADPH Oxidases; Phospholipases A; Phospholipases A2; Phosphorylation; Prostatic Neoplasms; Purinergic Agonists; Reactive Oxygen Species; Receptors, Purinergic; Ribosomal Protein S6 Kinases; Spheroids, Cellular; Thiourea; Tumor Cells, Cultured; Vitamin E | 2001 |
N-acetyl-L-cysteine enhances chemotherapeutic effect on prostate cancer cells.
Topics: Acetylcysteine; Antineoplastic Agents; Cisplatin; Etoposide; Humans; Interleukin-6; Male; NF-kappa B; Prostatic Neoplasms; Tumor Cells, Cultured | 2002 |
A possible regulatory role of glyoxalase I in cell viability of human prostate cancer.
Topics: Acetylcysteine; Cell Survival; Enzyme Inhibitors; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Humans; In Vitro Techniques; Lactoylglutathione Lyase; Male; Prostatic Neoplasms; Pyruvaldehyde; Tumor Cells, Cultured | 2002 |
[Topical use of N-acetyl-L-cysteine in some urological diseases].
Topics: Acetylcysteine; Aged; Humans; Male; Middle Aged; Postoperative Complications; Prostatic Hyperplasia; Prostatic Neoplasms; Urinary Bladder Diseases; Urinary Catheterization; Urinary Tract Infections; Urologic Diseases | 1968 |