acetylcysteine and Pancreatitis

acetylcysteine has been researched along with Pancreatitis in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.94)18.7374
1990's5 (14.71)18.2507
2000's21 (61.76)29.6817
2010's5 (14.71)24.3611
2020's2 (5.88)2.80

Authors

AuthorsStudies
Abdelhafez, D; Aboelkomsan, E; Ashur, S; El Sadik, A; Elshimy, A; Lasheen, N; Morcos, GNB1
Chen, Z; Dong, Y; Huang, W; Li, S; Niu, H; Su, W; Wan, C; Wen, E; Xin, G; Yang, X; Yu, X; Zhang, K; Zhang, Y1
Atayoğlu, K; Demirel, G; Gürleyik, G; Özkara, S1
Gong, J; Liu, D; Ma, Z; Meng, H; Qian, D; Song, G; Song, Z; Wang, Y; Yang, T; Zhou, B; Zhou, J1
Chen, F; Zhou, YJ1
Algin, MC; Bayhan, Z; Cosgun, S; Kahraman, C; Kocak, A; Koçak, C; Koçak, FE; Kocak, H; Metineren, MH; Savran, B; Zeren, S1
Collía, F; De Dios, I; Manso, MA; Ramudo, L; Yubero, S1
Arantes-Costa, FM; Landucci, EC; Leme, AS; Lichtenstein, A; Martins, MA1
Andersson, R; Börjesson, A; Haraldsen, P; Lasson, A; Olanders, K; Sun, ZW1
De Dios, I; De la Mano, AM; Manso, MA; Ramudo, L; Sevillano, S1
de Dios, I; de la Mano, AM; Manso, MA; Sevillano, S1
De Dios, I; de la Mano, AM; Manso, MA; Orfao, A; Sevillano, S1
Eddleston, JM; Mason, J; McCloy, RF; Schofield, D; Siriwardena, AK; Virlos, IT1
Cheng, WL; Qi, Y; Wang, X; Zhao, ZC; Zheng, SS1
Aydin, A; Balkan, M; Buyukdogan, V; Gul, H; Onguru, O; Sen, D; Simsek, A; Yagci, G; Yildiz, O; Zeybek, N1
Hardman, J; McMahon, R; Redmond, HP; Schofield, D; Shields, C; Siriwardena, AK1
De Dios, I; Manso, MA; Ramudo, L; Vicente, S1
Ates, B; Batçioğlu, K; Eşrefoğlu, M; Gül, M; Selimoğlu, MA1
Andersson, R; Lagergren, A; Shi, C; Sigvardsson, M; Wang, X; Zhao, X1
Degowska, M; Kierzkiewicz, M; Milewski, J; Rydzewska, G; Rydzewski, A1
Ateş, B; Eşrefoğlu, M; Gül, M; Yilmaz, I1
Bagul, A; Balachandra, S; Formela, L; Galloway, S; Hardman, JG; Jamdar, S; Mason, JM; Siriwardena, AK1
De Dios, I; Manso, MA; Ramudo, L; Vicente, S; Yubero, S1
Asaumi, H; Otsuki, M; Taguchi, M; Tashiro, M; Watanabe, S1
De Dios, I; Manso, MA; Ramudo, L1
Eşrefoğlu, M; Gül, M; Turan, F1
Bilton, D; Bottiglieri, T; Braganza, JM; Chaloner, C; Hunt, LP; Schofield, D; Scott, P; Shiel, N1
Andersson, R; Deng, XM; Haraldsen, P; Ihse, I; Wang, XD1
Blinman, TA; Gukovskaya, AS; Gukovsky, I; Pandol, SJ; Zaninovic, V1
Adler, G; Schmid, RM; Steinle, AU; Wagner, M; Weidenbach, H1
Grisham, MB1
Demols, A; Devière, J; Le Moine, O; Legros, F; Louis, H; Quertinmont, E; Van Laethem, JL1
Deng, JF; Lin, TJ; Yang, CC1
Braganza, JM; Holmes, AM; Kisher, R; Ku, R; Morton, AR; Stalley, L1

Trials

4 trial(s) available for acetylcysteine and Pancreatitis

ArticleYear
Intravenous n-acetylcysteine, ascorbic acid and selenium-based anti-oxidant therapy in severe acute pancreatitis.
    Scandinavian journal of gastroenterology, 2003, Volume: 38, Issue:12

    Topics: Acetylcysteine; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; alpha-Tocopherol; Antioxidants; Ascorbic Acid; beta Carotene; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Oxidative Stress; Pancreatitis; Selenium; Survival Rate

2003
N-acetylcysteine does not prevent post-endoscopic retrograde cholangiopancreatography hyperamylasemia and acute pancreatitis.
    World journal of gastroenterology, 2006, Jun-21, Volume: 12, Issue:23

    Topics: Acetylcysteine; Acute Disease; Amylases; Cholangiopancreatography, Endoscopic Retrograde; Endothelium, Vascular; Female; Free Radical Scavengers; Free Radicals; Humans; Hyperamylasemia; Male; Pancreatitis; Regression Analysis; Severity of Illness Index; Treatment Outcome

2006
Randomised, double blind, placebo controlled trial of intravenous antioxidant (n-acetylcysteine, selenium, vitamin C) therapy in severe acute pancreatitis.
    Gut, 2007, Volume: 56, Issue:10

    Topics: Acetylcysteine; Acute Disease; Adult; Aged; Antioxidants; APACHE; Ascorbic Acid; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Oxidative Stress; Pancreatitis; Selenium; Treatment Outcome

2007
Evidence for early oxidative stress in acute pancreatitis. Clues for correction.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1995, Volume: 17, Issue:1

    Topics: Acetylcysteine; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Antioxidants; Discriminant Analysis; Free Radical Scavengers; Humans; Linoleic Acid; Linoleic Acids; Middle Aged; Oxidative Stress; Pancreatitis; S-Adenosylmethionine

1995

Other Studies

30 other study(ies) available for acetylcysteine and Pancreatitis

ArticleYear
The Role of Mesenchymal Stem Cells with Ascorbic Acid and N-Acetylcysteine on TNF-
    Journal of diabetes research, 2021, Volume: 2021

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Blood Glucose; Body Weight; Caspase 3; Cell Proliferation; Ceruletide; Fluorescent Dyes; Insulin; Interleukin-1beta; Islets of Langerhans; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; NF-kappa B; Organic Chemicals; Pancreatitis; Proliferating Cell Nuclear Antigen; Rats; Regeneration; Tumor Necrosis Factor-alpha

2021
Activation of TLR4 induces severe acute pancreatitis-associated spleen injury via ROS-disrupted mitophagy pathway.
    Molecular immunology, 2022, Volume: 142

    Topics: Acetylcysteine; Animals; Apoptosis; Immunologic Factors; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Mitochondria; Mitophagy; Pancreas; Pancreatitis; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Spleen; Taurocholic Acid; Toll-Like Receptor 4; TOR Serine-Threonine Kinases; Tuftsin

2022
Effect of N-acetylcysteine on neutrophil functions during experimental acute pancreatitis.
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2017, Volume: 23, Issue:2

    Topics: Acetylcysteine; Acute Disease; Animals; Neutrophils; Pancreatitis; Rats; Rats, Wistar

2017
N-Acetylcysteine enhances the therapeutic efficacy of bone marrow-derived mesenchymal stem cell transplantation in rats with severe acute pancreatitis.
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2019, Volume: 19, Issue:2

    Topics: Acetylcysteine; Acute Disease; Animals; Bone Marrow Cells; Male; Mesenchymal Stem Cell Transplantation; Oxidative Stress; Pancreatitis; Random Allocation; Rats; Rats, Sprague-Dawley; Taurocholic Acid

2019
Hepatic effect of NAC on sevear acute pancteatise of rats.
    Asian Pacific journal of tropical medicine, 2014, Volume: 7, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Enzymes; Female; Liver; Male; Pancreatitis; Random Allocation; Rats; Rats, Sprague-Dawley

2014
Antioxidant Effect of Ukrain Versus N-Acetylcysteine Against Acute Biliary Pancreatitis in An Experimental Rat Model.
    Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2017, Volume: 30, Issue:2

    Topics: Acetylcysteine; Alanine Transaminase; Amylases; Animals; Antioxidants; Aspartate Aminotransferases; Berberine Alkaloids; Biliary Tract; Bilirubin; Disease Models, Animal; Humans; Lipase; Male; Malondialdehyde; Nitric Oxide; Oxidants; Oxidative Stress; Pancreas; Pancreatitis; Peroxidase; Phenanthridines; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha

2017
Evaluation of N-acetylcysteine treatment in acute pancreatitis-induced lung injury.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2012, Volume: 61, Issue:7

    Topics: Acetylcysteine; Amylases; Animals; Chemokine CCL2; Chemokine CXCL1; Disease Models, Animal; Free Radical Scavengers; Lung; Lung Injury; Male; Pancreatitis; Peroxidase; Rats; Rats, Wistar; RNA, Messenger; Taurocholic Acid

2012
Acute lung injury in experimental pancreatitis in rats: pulmonary protective effects of crotapotin and N-acetylcysteine.
    Shock (Augusta, Ga.), 2002, Volume: 18, Issue:5

    Topics: Acetylcysteine; Acute Disease; Animals; Crotoxin; Drug Interactions; Lung; Lung Injury; Male; Pancreas; Pancreatitis; Rats; Rats, Wistar

2002
Multimodal management - of value in fulminant acute pancreatitis?
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2003, Volume: 3, Issue:1

    Topics: Acetylcysteine; Acute Disease; Animals; Antibodies, Monoclonal; Capillary Permeability; Drug Therapy, Combination; Free Radical Scavengers; Imidazoles; Leucine; Male; Pancreatitis; Platelet Activating Factor; Platelet Endothelial Cell Adhesion Molecule-1; Rats; Rats, Sprague-Dawley

2003
Major pathological mechanisms of acute pancreatitis are prevented by N-acetylcysteine.
    Digestion, 2003, Volume: 68, Issue:1

    Topics: Acetylcysteine; Acute Disease; Animals; Free Radical Scavengers; Male; Microscopy, Electron; Oxidative Stress; Pancreas; Pancreatitis; Rats; Rats, Wistar

2003
N-acetylcysteine induces beneficial changes in the acinar cell cycle progression in the course of acute pancreatitis.
    Cell proliferation, 2003, Volume: 36, Issue:5

    Topics: Acetylcysteine; Acute Disease; Amylases; Animals; Cell Cycle; Flow Cytometry; Free Radicals; Male; Oxidative Stress; Pancreatitis; Rats; Rats, Wistar

2003
N-acetylcysteine prevents intra-acinar oxygen free radical production in pancreatic duct obstruction-induced acute pancreatitis.
    Biochimica et biophysica acta, 2003, Nov-20, Volume: 1639, Issue:3

    Topics: Acetylcysteine; Acute Disease; Amylases; Animals; Disease Models, Animal; Free Radical Scavengers; Free Radicals; Male; Pancreas; Pancreatic Ducts; Pancreatitis; Rats; Rats, Wistar

2003
Suppressing progress of pancreatitis through selective inhibition of NF-KappaB activation by using NAC.
    Journal of Zhejiang University. Science, 2004, Volume: 5, Issue:4

    Topics: Acetylcysteine; Animals; In Situ Hybridization; NF-kappa B; Pancreas; Pancreatitis; Rats; Rats, Wistar; RNA, Messenger; Tumor Necrosis Factor-alpha

2004
Beneficial effects of N-acetylcysteine on sodium taurocholate-induced pancreatitis in rats.
    Journal of gastroenterology, 2004, Volume: 39, Issue:3

    Topics: Acetylcysteine; Acute Disease; Amylases; Animals; Antioxidants; Cholagogues and Choleretics; Glutathione Peroxidase; Lipase; Male; Malondialdehyde; Nitrates; Nitrites; Pancreatitis; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Taurocholic Acid; Time Factors

2004
Intravenous antioxidant modulation of end-organ damage in L-arginine-induced experimental acute pancreatitis.
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2005, Volume: 5, Issue:4-5

    Topics: Acetylcysteine; Acute Disease; Amylases; Animals; Antioxidants; Arginine; Ascorbic Acid; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Drug Therapy, Combination; Injections, Intravenous; Lung; Male; Pancreas; Pancreatitis; Peroxidase; Proteins; Rats; Rats, Sprague-Dawley; Selenium; Time Factors

2005
Pro- and anti-inflammatory response of acinar cells during acute pancreatitis. Effect of N-acetyl cysteine.
    Cytokine, 2005, Nov-03, Volume: 32, Issue:3-4

    Topics: Acetylcysteine; Acute Disease; Animals; Bile Ducts; Cells, Cultured; Flow Cytometry; Hyperamylasemia; Inflammation Mediators; Interleukin-10; Male; Pancreas; Pancreatic Ducts; Pancreatitis; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2005
Antioxidative effect of melatonin, ascorbic acid and N-acetylcysteine on caerulein-induced pancreatitis and associated liver injury in rats.
    World journal of gastroenterology, 2006, Jan-14, Volume: 12, Issue:2

    Topics: Acetylcysteine; Acute Disease; Animals; Antioxidants; Ascorbic Acid; Ceruletide; Female; Lipid Peroxidation; Liver; Melatonin; Pancreatitis; Rats; Rats, Wistar; Reactive Oxygen Species

2006
Immune status and inflammatory response differ locally and systemically in severe acute pancreatitis.
    Scandinavian journal of gastroenterology, 2006, Volume: 41, Issue:4

    Topics: Acetylcysteine; Acute Disease; Animals; CD11b Antigen; Chemokines; Cytokines; Leukocyte Common Antigens; Male; Monocytes; NF-kappa B; Pancreas; Pancreatitis; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction

2006
Ultrastructural clues for the protective effect of ascorbic acid and N-acetylcysteine against oxidative damage on caerulein-induced pancreatitis.
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2006, Volume: 6, Issue:5

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Ceruletide; Female; Gastrointestinal Agents; Oxidative Stress; Pancreas; Pancreatitis; Rats; Rats, Sprague-Dawley

2006
ICAM-1 and CD11b/CD18 expression during acute pancreatitis induced by bile-pancreatic duct obstruction: effect of N-acetylcysteine.
    Experimental biology and medicine (Maywood, N.J.), 2007, Volume: 232, Issue:6

    Topics: Acetylcysteine; Animals; Antioxidants; CD11b Antigen; CD18 Antigens; Cholestasis; Disease Models, Animal; Intercellular Adhesion Molecule-1; Male; Monocytes; Neutrophils; Pancreas; Pancreatitis; Peroxidase; Rats; Rats, Wistar; RNA, Messenger; Up-Regulation

2007
Externally applied pressure activates pancreatic stellate cells through the generation of intracellular reactive oxygen species.
    American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 293, Issue:5

    Topics: Acetylcysteine; Animals; Antioxidants; Catechin; Kinetics; Models, Animal; Pancreas; Pancreatitis; Pressure; Rats; Reactive Oxygen Species; Reference Values; Superoxide Dismutase

2007
Extrapancreatic organ impairment during acute pancreatitis induced by bile-pancreatic duct obstruction. Effect of N-acetylcysteine.
    International journal of experimental pathology, 2007, Volume: 88, Issue:5

    Topics: Acetylcysteine; Acute Disease; Alanine Transaminase; Amylases; Animals; Aspartate Aminotransferases; Bilirubin; Biomarkers; Cholestasis; Creatinine; L-Lactate Dehydrogenase; Ligation; Liver; Lung; Male; Models, Animal; Multiple Organ Failure; Pancreas; Pancreatitis; Peroxidase; Rats; Rats, Wistar; Time Factors; Treatment Outcome

2007
Comparative effects of several therapatic agents on hepatic damage induced by acute experimental pancreatitis.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:5

    Topics: Acetylcysteine; Acute Disease; Animals; Antioxidants; Arginine; Ascorbic Acid; Ceruletide; Female; Liver Diseases; Melatonin; Pancreatitis; Pentoxifylline; Rats; Rats, Wistar; Statistics, Nonparametric

2008
Antioxidant and calcium channel blockers counteract endothelial barrier injury induced by acute pancreatitis in rats.
    Scandinavian journal of gastroenterology, 1995, Volume: 30, Issue:11

    Topics: Acetylcysteine; Acute Disease; Animals; Antioxidants; Calcium; Calcium Channel Blockers; Diltiazem; Endothelium; Free Radicals; Gastrointestinal Motility; Male; Pancreatitis; Permeability; Rats; Rats, Sprague-Dawley; Serum Albumin, Radio-Iodinated; Verapamil

1995
Early NF-kappaB activation is associated with hormone-induced pancreatitis.
    The American journal of physiology, 1998, Volume: 275, Issue:6

    Topics: Acetylcysteine; Animals; Antioxidants; Ceruletide; Chemokines; Cytokines; DNA-Binding Proteins; Gene Expression Regulation; I-kappa B Proteins; Interleukin-6; Isomerism; Kinetics; Male; NF-kappa B; Pancreas; Pancreatitis; Rats; Rats, Sprague-Dawley; Sincalide; Tumor Necrosis Factor-alpha

1998
NF-kappaB/Rel activation in cerulein pancreatitis.
    Gastroenterology, 1999, Volume: 116, Issue:2

    Topics: Acetylcysteine; Amylases; Animals; Antioxidants; Blotting, Northern; Blotting, Western; Ceruletide; DNA Probes; Dose-Response Relationship, Drug; Edema; Free Radical Scavengers; L-Lactate Dehydrogenase; Male; NF-kappa B; Pancreatitis; Pancreatitis-Associated Proteins; Protein Binding; Pyrrolidines; Rats; Rats, Wistar; Thiocarbamates

1999
NF-kappaB activation in acute pancreatitis: protective, detrimental, or inconsequential?
    Gastroenterology, 1999, Volume: 116, Issue:2

    Topics: Acetylcysteine; Acute Disease; Antioxidants; Cell Adhesion Molecules; Free Radical Scavengers; Humans; NF-kappa B; Pancreatitis; Pyrrolidines; Thiocarbamates

1999
N-acetylcysteine decreases severity of acute pancreatitis in mice.
    Pancreas, 2000, Volume: 20, Issue:2

    Topics: Acetylcysteine; Acute Disease; Amylases; Animals; Chemokine CCL2; Dose-Response Relationship, Drug; Female; Interleukin-6; Lipase; Male; Mice; Mice, Inbred BALB C; Pancreatitis; Survival Rate

2000
Pancytopenia, hyperglycemia, shock, coma, rhabdomyolysis, and pancreatitis associated with acetaminophen poisoning.
    Veterinary and human toxicology, 2001, Volume: 43, Issue:6

    Topics: Acetaminophen; Acetylcysteine; Adult; Anti-Inflammatory Agents, Non-Steroidal; Coma; Diagnosis, Differential; Drug Overdose; Fatal Outcome; Female; Free Radical Scavengers; Humans; Hyperglycemia; Liver Failure; Pancreatitis; Pancytopenia; Renal Insufficiency; Rhabdomyolysis; Shock; Suicide, Attempted

2001
Acetylcysteine to treat complications of pancreatitis.
    Lancet (London, England), 1986, Apr-19, Volume: 1, Issue:8486

    Topics: Acetylcysteine; Acute Disease; Humans; Male; Middle Aged; Pancreatitis; Respiratory Distress Syndrome

1986