acetylcysteine and Ovarian Neoplasms

acetylcysteine has been researched along with Ovarian Neoplasms in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.94)18.7374
1990's4 (11.76)18.2507
2000's9 (26.47)29.6817
2010's20 (58.82)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Choi, JH; Jang, DS; Kim, NJ; Lee, JY; Lee, KT; Preya, UH1
Ahn, JH; Choi, JH; Jang, DS; Jeong, M; Kim, HM; Lee, KT1
Aller, P; Alvarez, L; Barasoain, I; Díaz, JF; González-Maya, L; Lastres, P; Redondo-Horcajo, M; Romero-Estrada, A; Sánchez-Carranza, JN1
Hseu, YC; Hsu, CJ; Lee, CC; Lin, RW; Mathew, DC; Rajendran, P; Thigarajan, V; Yang, HL1
Årstad, E; Berndt, M; Gambhir, SS; Gendron, T; Glaser, M; Gowrishankar, G; Greenwood, HE; Hoehne, A; Koglin, N; Lewis, DY; Lythgoe, MF; Maddocks, ODK; McCormick, PN; Sander, K; Shuhendler, AJ; Witney, TH; Zhang, T1
Cho, HJ; Choi, KU; Kim, KH; Kim, YK; Moon, SH; Park, DY; Song, YJ; Suh, DS; Yoon, MS1
Haidari, M; Wakame, K; Zhang, W1
Chen, XX; Gong, LH; Jiang, QW; Mei, XL; Pan, SS; Qin, WM; Qiu, JG; Shi, Z; Wang, H; Xue, YQ; Yan, XJ; Zheng, FY1
Cao, L; Cheng, WH; Fu, Y; Tzeng, TJ; Zeng, H1
Dong, Y; Lin, X; Ma, J; Wang, C; Wang, Y; Yang, J; Zhang, N1
Lee, C1
Han, S; He, X; Li, X; Lu, J; Ouyang, J; Xie, F; Yi, C; Zhang, L; Zhu, L1
Bu, S; Lai, D; Wang, Q; Xue, L; Zhang, X; Zhu, X1
Coveñas, R; Geffard, M; Mangas, A; Pouns, O1
Haller, E; Mills, GB; Nanjundan, M; Patel, S; Raffoul, F; Smith, DM1
Choi, WH; Joo, WD; Kim, JH; Kim, YM; Kim, YT; Lee, HM; Nam, JH; Pak, JH1
Gajek, A; Jóźwiak, Z; Marczak, A; Rogalska, A; Szwed, M1
Brard, L; Horan, TC; Kim, KK; Lange, TS; Moore, RG; Singh, AP; Singh, RK; Vorsa, N1
Eißmann, F; Herz, C; Lamy, E; Mersch-Sundermann, V; Münstedt, K; Oey, D; Tinneberg, HR1
Best, C; Brum, G; Calianese, D; Cammarata, G; Carbone, T; Correia, V; Di, W; Higgins, K; Ji, F; Still, E; Szulak, K; Wan, Y1
Arbab, AS; Deeb, D; Gao, X; Gautam, SC; Liu, A; Liu, P; Liu, Y1
Bracci-Laudiero, L; Brunelli, R; Greco, G; Gustafsson, AC; Krasnowska, EK; Lundeberg, J; Lundeberg, T; Parasassi, T; Pittaluga, E; Romano, MC; Serafino, A1
Wong, AS; Zhou, HY1
Aiuchi, T; Ann, WW; Itabe, H; Nakajo, S; Nakaya, K; Sakairi, S; Shibayama-Imazu, T; Sonoda, I1
Bindoli, A; Folda, A; Gandin, V; Marzano, C; Rigobello, MP; Scutari, G1
Gorospe, M; Kawai, T; Otto, K; Rinker-Schaeffer, CW; Robinson, VL; Shalhav, O1
Mizutani, Y; Yoshida, O1
Guerrin, M; Lafon, C; Mathieu, C; Pierre, O; Valette, A; Vidal, S1
Abe, T; Gotoh, S; Higashi, K1
Baldin, V; Brichese, L; Chadebech, P; Valette, A; Vidal, S1
Bonvini, P; Hwang, SG; Li, Q; Mimnaugh, EG; Neckers, L; Reed, E; Trepel, J; Yunmbam, MK1
Lemoine, NR; Marani, M; McNeish, I; Tenev, T1
Li, QQ; Mimnaugh, EG; Neckers, L; Reed, E; Yu, JJ; Yunmbam, MK; Zhong, X1
Cervantes, A; Lankelma, J; Pinedo, HM; Schuurhuis, GJ1

Other Studies

34 other study(ies) available for acetylcysteine and Ovarian Neoplasms

ArticleYear
The natural terthiophene α-terthienylmethanol induces S phase cell cycle arrest of human ovarian cancer cells via the generation of ROS stress.
    Chemico-biological interactions, 2017, Jun-25, Volume: 272

    Topics: Acetylcysteine; Apoptosis; Cell Line, Tumor; Cyclin A; Cyclin-Dependent Kinase 2; DNA Damage; Eclipta; Female; Histones; Humans; Ovarian Neoplasms; Phosphorylation; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; S Phase Cell Cycle Checkpoints; Thiophenes

2017
9-Hydroxycanthin-6-one isolated from stem bark of Ailanthus altissima induces ovarian cancer cell apoptosis and inhibits the activation of tumor-associated macrophages.
    Chemico-biological interactions, 2018, Jan-25, Volume: 280

    Topics: Acetylcysteine; Ailanthus; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Caspase Inhibitors; Caspases; Cell Cycle Checkpoints; Cell Line, Tumor; Chemokines; Female; Humans; Indole Alkaloids; Macrophages; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Oligopeptides; Ovarian Neoplasms; Plant Bark; Reactive Oxygen Species; Vascular Endothelial Growth Factor A

2018
Gallic acid sensitizes paclitaxel-resistant human ovarian carcinoma cells through an increase in reactive oxygen species and subsequent downregulation of ERK activation.
    Oncology reports, 2018, Volume: 39, Issue:6

    Topics: Acetylcysteine; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Female; G2 Phase Cell Cycle Checkpoints; Gallic Acid; Gene Expression Regulation, Neoplastic; Humans; Ovarian Neoplasms; Paclitaxel; Reactive Oxygen Species

2018
Antrodia salmonea-induced oxidative stress abrogates HER-2 signaling cascade and enhanced apoptosis in ovarian carcinoma cells.
    Journal of cellular physiology, 2019, Volume: 234, Issue:3

    Topics: Acetylcysteine; Antioxidants; Antrodia; Apoptosis; Carcinoma; Female; Gene Expression Regulation, Neoplastic; Humans; Medicine, Chinese Traditional; Mitochondria; Ovarian Neoplasms; Oxidative Stress; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Receptor, ErbB-2; Signal Transduction

2019
Assessment of Tumor Redox Status through (
    Cancer research, 2019, 02-15, Volume: 79, Issue:4

    Topics: Acetylcysteine; Amino Acid Transport System y+; Animals; Apoptosis; Cell Proliferation; Cystadenocarcinoma, Serous; Female; Fluorine Radioisotopes; Free Radical Scavengers; Glutamates; Humans; Metabolomics; Mice; Mice, Inbred BALB C; Mice, Nude; Ovarian Neoplasms; Oxidation-Reduction; Positron-Emission Tomography; Radiopharmaceuticals; tert-Butylhydroperoxide; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2019
Silibinin inhibits tumor growth through downregulation of extracellular signal-regulated kinase and Akt in vitro and in vivo in human ovarian cancer cells.
    Journal of agricultural and food chemistry, 2013, May-01, Volume: 61, Issue:17

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Caspase 3; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Ki-67 Antigen; Mice; Mice, Inbred BALB C; Ovarian Neoplasms; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Silybin; Silymarin

2013
Disruption of endothelial adherens junction by invasive breast cancer cells is mediated by reactive oxygen species and is attenuated by AHCC.
    Life sciences, 2013, Dec-18, Volume: 93, Issue:25-26

    Topics: Acetylcysteine; Adherens Junctions; Antigens, CD; Antineoplastic Agents, Phytogenic; Antioxidants; beta Catenin; Breast Neoplasms; Cadherins; Cell Movement; Endothelial Cells; Endothelium, Vascular; Female; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Male; Ovarian Neoplasms; Plant Extracts; Prostatic Neoplasms; Reactive Oxygen Species; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine

2013
Piperlongumine induces apoptosis and synergizes with cisplatin or paclitaxel in human ovarian cancer cells.
    Oxidative medicine and cellular longevity, 2014, Volume: 2014

    Topics: Acetylcysteine; Apoptosis; Cell Line, Tumor; Cisplatin; Dioxolanes; Drug Synergism; Female; G2 Phase Cell Cycle Checkpoints; Humans; M Phase Cell Cycle Checkpoints; Ovarian Neoplasms; Paclitaxel; Reactive Oxygen Species

2014
Methylseleninic acid sensitizes Notch3-activated OVCA429 ovarian cancer cells to carboplatin.
    PloS one, 2014, Volume: 9, Issue:7

    Topics: Acetylcysteine; Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; Carboplatin; Cell Cycle; Cell Line, Tumor; Chromones; DNA-Binding Proteins; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Morpholines; Organoselenium Compounds; Ovarian Neoplasms; Phosphorylation; Receptor, Notch3; Receptors, Notch; RNA, Messenger; Thioxanthenes

2014
Emodin augments cisplatin cytotoxicity in platinum-resistant ovarian cancer cells via ROS-dependent MRP1 downregulation.
    BioMed research international, 2014, Volume: 2014

    Topics: Acetylcysteine; Cell Line, Tumor; Drug Resistance, Neoplasm; Emodin; Female; Gene Expression Regulation, Neoplastic; Humans; Multidrug Resistance-Associated Proteins; Ovarian Neoplasms; Reactive Oxygen Species

2014
Overexpression of Tyro3 receptor tyrosine kinase leads to the acquisition of taxol resistance in ovarian cancer cells.
    Molecular medicine reports, 2015, Volume: 12, Issue:1

    Topics: Acetylcysteine; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Oncogene Protein v-akt; Ovarian Neoplasms; Paclitaxel; Phosphorylation; Receptor Protein-Tyrosine Kinases; RNA, Messenger; Signal Transduction

2015
Mild oxidative stress induced by a low dose of cisplatin contributes to the escape of TRAIL-mediated apoptosis in the ovarian cancer SKOV3 cell line.
    Oncology reports, 2016, Volume: 35, Issue:6

    Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cisplatin; Drug Tolerance; Female; Humans; Ovarian Neoplasms; Oxidative Stress; TNF-Related Apoptosis-Inducing Ligand

2016
Autophagy protects ovarian cancer-associated fibroblasts against oxidative stress.
    Cell cycle (Georgetown, Tex.), 2016, 05-18, Volume: 15, Issue:10

    Topics: Acetylcysteine; Actins; Autophagy; Autophagy-Related Protein 5; Cancer-Associated Fibroblasts; Cell Proliferation; Cell Survival; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Female; Fibroblasts; Humans; Hydrogen Peroxide; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Monocarboxylic Acid Transporters; Muscle Proteins; Ovarian Neoplasms; Oxidative Stress; Reactive Oxygen Species; S Phase Cell Cycle Checkpoints; Superoxide Dismutase

2016
Circulating antibodies directed against "polycyclic aromatic hydrocarbon-like" structures in the sera of cancer patients.
    Cancer epidemiology, 2009, Volume: 33, Issue:1

    Topics: Acetylcysteine; Antibodies, Neoplasm; Antibody Affinity; Antibody Specificity; Breast Neoplasms; Carrier Proteins; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoglobulin A; Immunoglobulins; Ligands; Menopause; Ovarian Neoplasms; Polycyclic Aromatic Hydrocarbons; Receptors, Aryl Hydrocarbon; Serum Albumin, Bovine

2009
Arsenic trioxide induces a beclin-1-independent autophagic pathway via modulation of SnoN/SkiL expression in ovarian carcinoma cells.
    Cell death and differentiation, 2010, Volume: 17, Issue:12

    Topics: Acetylcysteine; Apoptosis Regulatory Proteins; Arsenic Trioxide; Arsenicals; Autophagy; Autophagy-Related Protein 5; Autophagy-Related Protein 7; Beclin-1; Carcinoma; Cell Line, Tumor; Female; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Microtubule-Associated Proteins; Multidrug Resistance-Associated Proteins; Ovarian Neoplasms; Oxides; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Signal Transduction; Transforming Growth Factor beta; Ubiquitin-Activating Enzymes

2010
Peroxiredoxin 6 overexpression attenuates cisplatin-induced apoptosis in human ovarian cancer cells.
    Cancer investigation, 2011, Volume: 29, Issue:1

    Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Activation; Female; Humans; Ovarian Neoplasms; Peroxiredoxin VI; Reactive Oxygen Species; Signal Transduction; Time Factors; Transfection; Up-Regulation

2011
The role of reactive oxygen species in WP 631-induced death of human ovarian cancer cells: a comparison with the effect of doxorubicin.
    Toxicology in vitro : an international journal published in association with BIBRA, 2011, Volume: 25, Issue:8

    Topics: Acetylcysteine; Antibiotics, Antineoplastic; Antioxidants; Apoptosis; Cell Line, Tumor; Cell Survival; Daunorubicin; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; Membrane Potential, Mitochondrial; Ovarian Neoplasms; Reactive Oxygen Species

2011
Cytotoxic properties of Adamantyl isothiocyanate and potential in vivo metabolite adamantyl-N-acetylcystein in gynecological cancer cells.
    Chemical biology & drug design, 2012, Volume: 79, Issue:1

    Topics: Acetylcysteine; Adamantane; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Drug Design; Drug Screening Assays, Antitumor; Female; G2 Phase Cell Cycle Checkpoints; Humans; Isothiocyanates; Mitogen-Activated Protein Kinases; Ovarian Neoplasms; Protein Kinase Inhibitors; Reactive Oxygen Species

2012
Erucin and benzyl isothiocyanate suppress growth of late stage primary human ovarian carcinoma cells and telomerase activity in vitro.
    Phytotherapy research : PTR, 2013, Volume: 27, Issue:7

    Topics: Acetylcysteine; Apoptosis; Cell Line, Tumor; Cell Survival; DNA Fragmentation; Down-Regulation; Female; G2 Phase; Humans; Isothiocyanates; Mitochondrial Membranes; Ovarian Neoplasms; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Sulfides; Telomerase; Thiocyanates

2013
N-acetylcysteine potentiates doxorubicin-induced ATM and p53 activation in ovarian cancer cells.
    International journal of oncology, 2013, Volume: 42, Issue:1

    Topics: Acetylcysteine; Antibiotics, Antineoplastic; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cytoskeletal Proteins; DNA-Binding Proteins; Doxorubicin; Drug Synergism; Female; Free Radical Scavengers; Histones; Humans; Ovarian Neoplasms; Protein Serine-Threonine Kinases; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

2013
ROS mediate proapoptotic and antisurvival activity of oleanane triterpenoid CDDO-Me in ovarian cancer cells.
    Anticancer research, 2013, Volume: 33, Issue:1

    Topics: Acetylcysteine; Apoptosis; Cell Line, Tumor; Cell Proliferation; Female; Humans; Hydrogen Peroxide; Oleanolic Acid; Ovarian Neoplasms; Reactive Oxygen Species; Signal Transduction

2013
Differentiation of normal and cancer cells induced by sulfhydryl reduction: biochemical and molecular mechanisms.
    Cell death and differentiation, 2005, Volume: 12, Issue:10

    Topics: Acetylcysteine; beta Catenin; Cadherins; Cell Adhesion; Cell Adhesion Molecules; Cell Differentiation; Cell Line, Tumor; Colonic Neoplasms; CSK Tyrosine-Protein Kinase; Cytoskeletal Proteins; Female; Humans; Keratinocytes; Ovarian Neoplasms; Phosphotransferases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction; src-Family Kinases; Sulfhydryl Compounds; Thymidine; Trans-Activators

2005
Activation of p70S6K induces expression of matrix metalloproteinase 9 associated with hepatocyte growth factor-mediated invasion in human ovarian cancer cells.
    Endocrinology, 2006, Volume: 147, Issue:5

    Topics: Acetylcysteine; Blotting, Western; Cell Line, Tumor; Cell Movement; Down-Regulation; Enzyme Activation; Extracellular Matrix; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Hepatocyte Growth Factor; Humans; Immunoblotting; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Models, Statistical; Neoplasm Invasiveness; Neoplasm Metastasis; Neurons; Ovarian Neoplasms; Phenotype; Phosphatidylinositol 3-Kinases; Phosphorylation; Promoter Regions, Genetic; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Time Factors; Transfection

2006
Production of superoxide and dissipation of mitochondrial transmembrane potential by vitamin K2 trigger apoptosis in human ovarian cancer TYK-nu cells.
    Apoptosis : an international journal on programmed cell death, 2006, Volume: 11, Issue:9

    Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; alpha-Tocopherol; Apoptosis; Cycloheximide; Diterpenes; Female; Humans; Membrane Potentials; Mitochondria; Ovarian Neoplasms; Reactive Oxygen Species; Superoxides; Tumor Cells, Cultured; Vitamin K 2

2006
Inhibition of thioredoxin reductase by auranofin induces apoptosis in cisplatin-resistant human ovarian cancer cells.
    Free radical biology & medicine, 2007, Mar-15, Volume: 42, Issue:6

    Topics: Acetylcysteine; Antineoplastic Agents; Antirheumatic Agents; Apoptosis; Auranofin; Cell Line, Tumor; Cisplatin; Cytochromes c; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Humans; Mitochondria; Ovarian Neoplasms; Thioredoxin-Disulfide Reductase

2007
Mitogen-activated protein kinase kinase 4/c-Jun NH2-terminal kinase kinase 1 protein expression is subject to translational regulation in prostate cancer cell lines.
    Molecular cancer research : MCR, 2008, Volume: 6, Issue:3

    Topics: Acetylcysteine; Blotting, Northern; Cell Line, Tumor; Cycloheximide; Dactinomycin; Ethanol; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Male; MAP Kinase Kinase 4; Neoplasm Metastasis; Ovarian Neoplasms; Polymerase Chain Reaction; Prostatic Neoplasms; Protein Biosynthesis

2008
Overcoming tumor necrosis factor-alpha resistance of human renal and ovarian carcinoma cells by combination treatment with buthionine sulfoximine and tumor necrosis factor-alpha. Role of tumor necrosis factor-alpha mRNA down-regulation in tumor cell sensi
    Cancer, 1994, Feb-01, Volume: 73, Issue:3

    Topics: Acetylcysteine; Antimetabolites, Antineoplastic; Blotting, Northern; Buthionine Sulfoximine; Carcinoma, Renal Cell; Down-Regulation; Drug Resistance; Drug Synergism; Female; Glutathione; Humans; Kidney Neoplasms; Methionine Sulfoximine; Ovarian Neoplasms; RNA, Messenger; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1994
Transforming growth factor beta 1-induced apoptosis in human ovarian carcinoma cells: protection by the antioxidant N-acetylcysteine and bcl-2.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1996, Volume: 7, Issue:8

    Topics: Acetylcysteine; Adenocarcinoma; Apoptosis; Blotting, Northern; Blotting, Western; Cell Division; DNA Fragmentation; Female; Genes, fos; Genes, jun; Humans; Hydrogen Peroxide; Ovarian Neoplasms; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Time Factors; Transfection; Transforming Growth Factor beta; Tumor Cells, Cultured

1996
Attenuation by glutathione of hsp72 gene expression induced by cadmium in cisplatin-resistant human ovarian cancer cells.
    Biochemical pharmacology, 1999, Jul-01, Volume: 58, Issue:1

    Topics: Acetylcysteine; Cadmium Chloride; Cisplatin; DNA-Binding Proteins; Drug Resistance, Neoplasm; Female; Free Radical Scavengers; Gene Expression; Glutathione; Heat Shock Transcription Factors; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Humans; Mutagens; Ovarian Neoplasms; RNA, Messenger; Transcription Factors; Tumor Cells, Cultured

1999
Phosphorylation and proteasome-dependent degradation of Bcl-2 in mitotic-arrested cells after microtubule damage.
    Biochemical and biophysical research communications, 1999, Sep-07, Volume: 262, Issue:3

    Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Apoptosis; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Female; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Humans; Leupeptins; Microtubules; Mitosis; Multienzyme Complexes; Ovarian Neoplasms; Paclitaxel; Phosphorylation; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured; Virulence Factors, Bordetella

1999
Prevention of cisplatin-DNA adduct repair and potentiation of cisplatin-induced apoptosis in ovarian carcinoma cells by proteasome inhibitors.
    Biochemical pharmacology, 2000, Nov-01, Volume: 60, Issue:9

    Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Cells, Cultured; Chromatin; Cisplatin; Cysteine Endopeptidases; Cytosol; DNA; DNA Adducts; DNA Repair; DNA-Binding Proteins; Drug Interactions; Endonucleases; Enzyme Inhibitors; Female; Histones; Humans; Leucine; Multienzyme Complexes; Ovarian Neoplasms; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteasome Endopeptidase Complex; Protein Biosynthesis; Proteins; RNA, Messenger; Ubiquitins

2000
Pro-caspase-3 overexpression sensitises ovarian cancer cells to proteasome inhibitors.
    Cell death and differentiation, 2001, Volume: 8, Issue:3

    Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Caspase 3; Caspases; Cell Division; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Enzyme Induction; Female; Flow Cytometry; G2 Phase; Glycoproteins; Humans; Immunoblotting; Isoenzymes; Leupeptins; Ovarian Neoplasms; Transfection

2001
Lactacystin enhances cisplatin sensitivity in resistant human ovarian cancer cell lines via inhibition of DNA repair and ERCC-1 expression.
    Cellular and molecular biology (Noisy-le-Grand, France), 2001, Volume: 47 Online Pub

    Topics: Acetylcysteine; Antineoplastic Agents; Cisplatin; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA Damage; DNA Repair; DNA-Binding Proteins; DNA, Neoplasm; Drug Resistance, Neoplasm; Drug Synergism; Endonucleases; Female; Gene Expression; Humans; Multienzyme Complexes; Ovarian Neoplasms; Proteasome Endopeptidase Complex; Proteins; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured

2001
The role of oxygen-derived free radicals in the cytotoxicity of doxorubicin in multidrug resistant and sensitive human ovarian cancer cells.
    Cancer letters, 1988, Aug-15, Volume: 41, Issue:2

    Topics: Acetylcysteine; Ascorbic Acid; Benzoates; Benzoic Acid; Catalase; Cell Division; Cell Survival; Doxorubicin; Drug Resistance; Female; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Kinetics; Mannitol; Ovarian Neoplasms; Oxygen; Superoxide Dismutase; Tumor Cells, Cultured

1988