acetylcysteine and Osteosarcoma

acetylcysteine has been researched along with Osteosarcoma in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (17.65)18.2507
2000's3 (17.65)29.6817
2010's10 (58.82)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Feng, W; Li, X; Liao, S; Lin, C; Liu, J; Liu, Y; Moro, A; Wang, C; Wang, K1
Bi, Z; Chen, Y; Geng, S; Liu, R; Sun, J; Tu, H; Wang, X; Zhang, Y; Zou, J1
Jiao, Y; Ju, Y; Li, W; Liu, Y; Wang, S; Wang, Y; Zhang, B; Zhang, J; Zhang, M; Zhao, L; Zhao, M; Zhao, Y1
Han, H; Huang, J; Wang, H; Ye, F; Zhang, L; Zou, Y1
Yang, ML; Ye, ZM1
Du, X; Huang, Q; Li, K; Ou, Y; Tao, Y; Tu, P; Yin, H1
Li, J; Li, K; Li, X; Sun, N; Tian, J; Wang, H1
Lee, SY; Lin, CH; Lin, KF; Lin, YM; Mar, K1
Arbon, KS; Harvey, WA; Heggland, SJ; Hunt, LM; Reyes, JR; Smith, SS1
Chang, IC; Chiang, TI; Hsu, LS; Huang, YJ; Yeh, CW1
Katsuda, H; Katsura, H; Miyamoto, K; Nagata, N; Sai, Y; Waki, Y; Yamashita, M; Yu, J1
Kim, NR; Lim, BS; Park, HC; Son, KM; Yang, HC1
Calvaruso, G; D'Anneo, A; Emanuele, S; Giuliano, M; Lauricella, M; Tesoriere, G; Vento, R1
Chang, YC; Kwon, TK; Lim, JH; Park, JW; Park, YB1
Corey, EJ; Fenteany, G; Reichard, GA; Schreiber, SL; Standaert, RF1
Ishiguro, N; Iwata, H; Izumi, R; Kambe, F; Kurokouchi, K; Seo, H; Yasukawa, K1
Boulaire, J; Cannella, D; Fitzgerald, P; Fotedar, A; Fotedar, R; Rousseau, D1

Other Studies

17 other study(ies) available for acetylcysteine and Osteosarcoma

ArticleYear
Polyphyllin VII induces apoptosis and autophagy via mediating H2O2 levels and the JNK pathway in human osteosarcoma U2OS cells.
    Oncology reports, 2021, Volume: 45, Issue:1

    Topics: Acetylcysteine; Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Humans; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Osteosarcoma; Saponins

2021
Deoxyelephantopin Induces Reactive Oxygen Species-Mediated Apoptosis and Autophagy in Human Osteosarcoma Cells.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2017, Volume: 42, Issue:5

    Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Bone Neoplasms; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Survival; Humans; Lactones; Membrane Potential, Mitochondrial; Mitochondria; Osteosarcoma; Reactive Oxygen Species; Sesquiterpenes

2017
A novel androstenedione derivative induces ROS-mediated autophagy and attenuates drug resistance in osteosarcoma by inhibiting macrophage migration inhibitory factor (MIF).
    Cell death & disease, 2014, Aug-07, Volume: 5

    Topics: Acetylcysteine; Adenine; Androstenedione; Autophagy; Bone Neoplasms; Cell Line, Tumor; Down-Regulation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; HMGB1 Protein; Humans; Macrophage Migration-Inhibitory Factors; Osteosarcoma; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Secosteroids; Translocation, Genetic

2014
Baicalein induces human osteosarcoma cell line MG-63 apoptosis via ROS-induced BNIP3 expression.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2015, Volume: 36, Issue:6

    Topics: Acetylcysteine; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Flavanones; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Membrane Potential, Mitochondrial; Membrane Proteins; Osteosarcoma; Proto-Oncogene Proteins; Reactive Oxygen Species

2015
[Extremely low frequency electromagnetic field induces apoptosis of osteosarcoma cells via oxidative stress].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2015, Volume: 44, Issue:3

    Topics: Acetylcysteine; Apoptosis; Cell Line, Tumor; Cell Proliferation; Electromagnetic Fields; Humans; Imidazoles; Osteosarcoma; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Reactive Oxygen Species

2015
Aloe-emodin-mediated photodynamic therapy induces autophagy and apoptosis in human osteosarcoma cell line MG‑63 through the ROS/JNK signaling pathway.
    Oncology reports, 2016, Volume: 35, Issue:6

    Topics: Acetylcysteine; Anthracenes; Anthraquinones; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Osteosarcoma; Photochemotherapy; Photosensitizing Agents; Reactive Oxygen Species

2016
Diallyl trisulfide induces osteosarcoma cell apoptosis through reactive oxygen species-mediated downregulation of the PI3K/Akt pathway.
    Oncology reports, 2016, Volume: 35, Issue:6

    Topics: Acetylcysteine; Allyl Compounds; Antineoplastic Agents; Antioxidants; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromones; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; G1 Phase Cell Cycle Checkpoints; Humans; Membrane Potential, Mitochondrial; Mitochondria; Morpholines; Osteosarcoma; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Sulfides

2016
Antioxidant N-Acetylcysteine and Glutathione Increase the Viability and Proliferation of MG63 Cells Encapsulated in the Gelatin Methacrylate/VA-086/Blue Light Hydrogel System.
    Tissue engineering. Part C, Methods, 2016, Volume: 22, Issue:8

    Topics: Acetamides; Acetylcysteine; Antioxidants; Azo Compounds; Bone Neoplasms; Cell Proliferation; Cell Survival; Cross-Linking Reagents; Gelatin; Glutathione; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Light; Methacrylates; Osteosarcoma; Reactive Oxygen Species; Tumor Cells, Cultured

2016
Cadmium-induced decrease in RUNX2 mRNA expression and recovery by the antioxidant N-acetylcysteine (NAC) in the human osteoblast-like cell line, Saos-2.
    Toxicology in vitro : an international journal published in association with BIBRA, 2009, Volume: 23, Issue:1

    Topics: Acetylcysteine; Apoptosis; Cadmium Chloride; Cell Line, Tumor; Cell Survival; Core Binding Factor Alpha 1 Subunit; Dose-Response Relationship, Drug; Drug Antagonism; Environmental Pollutants; Free Radical Scavengers; Gene Expression; Glutathione; Humans; Lipid Peroxidation; Osteoblasts; Osteosarcoma; Oxidative Stress; Reactive Oxygen Species; RNA, Messenger

2009
Shikonin induces apoptosis through reactive oxygen species/extracellular signal-regulated kinase pathway in osteosarcoma cells.
    Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:5

    Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Extracellular Signal-Regulated MAP Kinases; Humans; Inhibitory Concentration 50; Naphthoquinones; Osteosarcoma; Phosphorylation; Phytotherapy; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species

2010
Protecting cisplatin-induced nephrotoxicity with cimetidine does not affect antitumor activity.
    Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:11

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Bone Neoplasms; Cell Line; Cell Line, Tumor; Cimetidine; Cisplatin; Infusions, Intravenous; Kidney; Male; Organic Cation Transport Proteins; Osteosarcoma; Platinum; Rats; Rats, Wistar; Reactive Oxygen Species; Renal Agents

2010
Effects of N-acetylcysteine on TEGDMA- and HEMA-induced suppression of osteogenic differentiation of human osteosarcoma MG63 cells.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2011, Volume: 98, Issue:2

    Topics: Acetylcysteine; Active Transport, Cell Nucleus; Cell Differentiation; Cell Line, Tumor; Composite Resins; Humans; Methacrylates; NF-E2-Related Factor 2; Osteogenesis; Osteosarcoma; Oxidative Stress; Polyethylene Glycols; Polymethacrylic Acids

2011
Induction of apoptosis in human osteosarcoma Saos-2 cells by the proteasome inhibitor MG132 and the protective effect of pRb.
    Cell death and differentiation, 2003, Volume: 10, Issue:8

    Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Antioxidants; Apoptosis; bcl-X Protein; Blotting, Western; Caspase 3; Caspase 8; Caspases; Cell Line, Tumor; Cell Survival; Cysteine Endopeptidases; Cytochromes c; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Leupeptins; Membrane Potentials; Microscopy, Fluorescence; Mitochondria; Multienzyme Complexes; Osteosarcoma; Protease Inhibitors; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Retinoblastoma Protein; Time Factors; Transfection; Tumor Suppressor Protein p53

2003
Transcriptional repression of E2F gene by proteasome inhibitors in human osteosarcoma cells.
    Biochemical and biophysical research communications, 2004, Jun-11, Volume: 318, Issue:4

    Topics: Acetylcysteine; Antioxidants; Cell Cycle Proteins; Cell Line, Tumor; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Down-Regulation; E2F Transcription Factors; E2F1 Transcription Factor; E2F2 Transcription Factor; Glutathione; Humans; Leupeptins; Multienzyme Complexes; Osteosarcoma; Transcription Factors; Transcription, Genetic; Transfection

2004
A beta-lactone related to lactacystin induces neurite outgrowth in a neuroblastoma cell line and inhibits cell cycle progression in an osteosarcoma cell line.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Apr-12, Volume: 91, Issue:8

    Topics: Acetylcysteine; Anti-Bacterial Agents; Cell Cycle; Cytoskeleton; Humans; In Vitro Techniques; Lactones; Neurites; Neuroblastoma; Osteosarcoma; Structure-Activity Relationship; Tumor Cells, Cultured

1994
TNF-alpha increases expression of IL-6 and ICAM-1 genes through activation of NF-kappaB in osteoblast-like ROS17/2.8 cells.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1998, Volume: 13, Issue:8

    Topics: Acetylcysteine; Animals; Bone Neoplasms; Cytosol; Free Radical Scavengers; Intercellular Adhesion Molecule-1; Interleukin-6; NF-kappa B; Osteoblasts; Osteosarcoma; Rats; RNA, Messenger; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1998
Growth inhibition by CDK-cyclin and PCNA binding domains of p21 occurs by distinct mechanisms and is regulated by ubiquitin-proteasome pathway.
    Oncogene, 1999, Jul-29, Volume: 18, Issue:30

    Topics: 3T3 Cells; Acetylcysteine; Animals; CDC2-CDC28 Kinases; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Gene Deletion; Gene Expression Regulation, Neoplastic; Growth Inhibitors; Hemagglutinins; Humans; Leupeptins; Mice; Models, Genetic; Multienzyme Complexes; Mutagenesis; Osteosarcoma; Proliferating Cell Nuclear Antigen; Proteasome Endopeptidase Complex; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Time Factors; Transfection; Tumor Cells, Cultured; Ubiquitins

1999