acetylcysteine and Obesity

acetylcysteine has been researched along with Obesity in 31 studies

Research

Studies (31)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	9 (29.03)	29.6817
2010's	10 (32.26)	24.3611
2020's	12 (38.71)	2.80

Authors

Authors	Studies
Chabowski, A; Kasacka, I; Wołosowicz, M; Łukaszuk, B	1
Christou, DD; Ferreira, LF; Hahn, D; Kelley, RC; Lapierre, SS; Muscato, DR	1
Barra, R; Burgos, H; Constandil, L; Hernández, A; Morgan, C; Ramírez, P; Reyes, A; Ríos, M; Sáez-Briones, P; Zepeda-Morales, K	1
Awasthi, S; Garg, R; Horne, D; Salgia, R; Singhal, S; Singhal, SS	1
Bakirhan, EG; Terzi, F; Tüfekci, KK	1
Comin, VH; Luiz, KD; Pieri, BLDS; Rodrigues, MS; Silveira, GB; Silveira, PCL; Venturini, LM; Zaccaron, RP	1
Feng, X; Jin, R; Liu, X; Ma, L; Shan, Y; Wang, Y; Yang, Z; Yi, M; Zhao, B	1
Chang, CS; Chang, YH; Chuang, JH; Lian, WS; Lin, CY; Lin, HY; Lin, TK; Liou, CW; Shen, FC; Su, YJ; Tsao, CF; Wang, PW; Weng, SW	1
Du, X; Guo, LL; Liu, L; Liu, YS; Tian, F; Wen, T; Xiang, QY; Xu, J; Zhu, LY	1
Akpunonu, P; Bailey, AM; Baum, RA; Geraghty, L; Howell, MM; Mohan, S; Su, MK; Weant, KA; Webb, AN; Woolum, JA	1
Battista, D; Brown, RM; Lawrence, AJ; Perry, CJ; Sketriene, D; Sumithran, P	1
Bains, JS; Borgland, SL; Gordon, GR; Kaur, M; Lau, BK; Murphy-Royal, C; Qiao, M	1
Chomchai, C; Chomchai, S	1
Chang, CS; Chuang, JH; Lian, WS; Lin, CY; Lin, HY; Lin, TK; Liou, CW; Shen, FC; Tsao, CF; Wang, PW; Weng, SW	1
Arbelaez, LG; Castro, MC; Francini, F; Massa, ML; Schinella, G; Spinedi, E; Villagarcía, HG	1
Cirilli, I; Dludla, PV; Louw, J; Marcheggiani, F; Mazibuko-Mbeje, SE; Mxinwa, V; Nkambule, BB; Nyambuya, TM; Tiano, L	1
Chang, YC; Chen, YH; Chen, YR; Chuang, LM; Hwang, JJ; Lee, WH; Lee, WJ; Shew, JY; Wei, PC; Yu, YH	1
Cao, JJ; Picklo, MJ	1
Tew, KD; Townsend, DM; Ye, ZW; Zhang, J	1
Gao, M; Liu, D; Ma, Y	1
Choi, JW; Kim, AY; Kim, JB; Kim, M; Lee, YS; Masuzaki, H; Park, KS; Son, HJ; Yasue, S	1
Espiritu, DJ; Mazzone, T	1
Assalin, HB; Ebaid, GX; Fernandes, AA; Mani, F; Novelli, EL; Rocha, K; Santos, PP; Seiva, FR; Souza, G	1
Andrikopoulos, S; Boivin, B; Bruce, C; Cai, X; Crack, PJ; Deng, H; Febbraio, MA; Fukushima, A; Galic, S; Loh, K; Mitchell, CA; Ooms, LM; Shields, BJ; Skiba, B; Stepto, N; Tiganis, T; Tonks, NK; Watt, MJ; Wu, B	1
Crum, A; Crum, AC; French, SW; Kim, H; Kim, HJ; Norris, KC; Rajavashisth, TB; Shen, R; Sinha-Hikim, AP; Sinha-Hikim, I; Vaziri, ND	1
Corkey, BE; Ferrante, T; Haller, JF; Krawczyk, SA; Zoeller, RA	1
Anfossi, G; Massucco, P; Mattiello, L; Russo, I; Trovati, M	1
Bellou, V; Bodens, A; Dröge, W; Dugi, K; Edler, L; Hamann, A; Hildebrandt, W; Kinscherf, R; Krakowski-Roosen, H; Lacher, S; Nawroth, P; Nöbel, N; Sauer, R	1
Allister, EM; Bikopoulos, G; Fantus, IG; Giacca, A; Lewis, GF; Naassan, A; Oprescu, AI; Park, E; Rozakis-Adcock, M; Tang, C; Uchino, H; Wheeler, MB	1
Zhang, J	1
Giacca, A; Lewis, GF; Xiao, C	1

Reviews

3 review(s) available for acetylcysteine and Obesity

Article	Year
RLIP: A necessary transporter protein for translating oxidative stress into pro-obesity and pro-carcinogenic signaling. Biochimica et biophysica acta. Reviews on cancer, 2022, Volume: 1877, Issue:5 Topics: Acetylcysteine; Adipokines; Animals; Carcinogenesis; Carcinogens; Carrier Proteins; Clathrin; Cytokines; Epidermal Growth Factor; GTPase-Activating Proteins; Humans; Infant; Insulins; Male; Mice; Neoplasms; Obesity; Oxidative Stress; Peptide Hormones; Transforming Growth Factor beta; Tumor Suppressor Protein p53	2022
The beneficial effects of N-acetyl cysteine (NAC) against obesity associated complications: A systematic review of pre-clinical studies. Pharmacological research, 2019, Volume: 146 Topics: Acetylcysteine; Animals; Humans; Inflammation; Obesity; Oxidative Stress; Transcription Factors	2019
Oxidative stress, redox regulation and diseases of cellular differentiation. Biochimica et biophysica acta, 2015, Volume: 1850, Issue:8 Topics: Acetylcysteine; Cell Differentiation; Free Radical Scavengers; Humans; Models, Biological; Obesity; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Signal Transduction	2015

Trials

1 trial(s) available for acetylcysteine and Obesity

Article	Year
Effect of thiol antioxidant on body fat and insulin reactivity. Journal of molecular medicine (Berlin, Germany), 2004, Volume: 82, Issue:5 Topics: Acetylcysteine; Adipose Tissue; Adult; Antioxidants; Body Weight; Cell Line; Creatine; Cysteine; Cystine; Female; Glucose Tolerance Test; Humans; Hyperlipidemias; Insulin; Male; Middle Aged; Obesity; Receptor, Insulin; Sulfhydryl Compounds	2004

Other Studies

27 other study(ies) available for acetylcysteine and Obesity

Article	Year
Diverse Impact of N-Acetylcysteine or Alpha-Lipoic Acid Supplementation during High-Fat Diet Regime on Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 in Visceral and Subcutaneous Adipose Tissue. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2022, Apr-15, Volume: 56, Issue:2 Topics: Acetylcysteine; Animals; Antioxidants; Diet, High-Fat; Dietary Supplements; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Obesity; Rats; Rats, Wistar; Subcutaneous Fat; Thioctic Acid	2022
Cardiac and respiratory muscle responses to dietary N-acetylcysteine in rats consuming a high-saturated fat, high-sucrose diet. Experimental physiology, 2022, Volume: 107, Issue:11 Topics: Acetylcysteine; Animals; Antioxidants; Diet, High-Fat; Fatty Acids; Male; Obesity; Rats; Rats, Wistar; Respiratory Muscles; Sucrose	2022
Prefrontal Cortical Control of Activity in Nucleus Accumbens Core Is Weakened by High-Fat Diet and Prevented by Co-Treatment with N-Acetylcysteine: Implications for the Development of Obesity. International journal of molecular sciences, 2022, Sep-03, Volume: 23, Issue:17 Topics: Acetylcysteine; Animals; Diet, High-Fat; Humans; Male; Mice; Nucleus Accumbens; Obesity; Prefrontal Cortex; Weight Gain	2022
A Maternal High-Fat Diet Causes Anxiety-Related Behaviors by Altering Neuropeptide Y1 Receptor and Hippocampal Volumes in Rat Offspring: the Potential Effect of N-Acetylcysteine. Molecular neurobiology, 2023, Volume: 60, Issue:3 Topics: Acetylcysteine; Animals; Anxiety; Diet, High-Fat; Female; Hippocampus; Humans; Male; Obesity; Obesity, Maternal; Pregnancy; Rats	2023
Reduction of oxidative stress improves insulin signaling in cardiac tissue of obese mice. Einstein (Sao Paulo, Brazil), 2020, Volume: 18 Topics: Acetylcysteine; Animals; Blood Glucose; Blotting, Western; Body Weight; Diet, High-Fat; Fluoresceins; Free Radical Scavengers; Humans; Insulin Resistance; Male; Mice; Myocardium; Obesity; Oxidative Stress; Protein Carbonylation; Reactive Oxygen Species; Reference Values; Spectrophotometry	2020
Correlation between oxidative stress and NF-κB signaling pathway in the obesity-asthma mice. Molecular biology reports, 2020, Volume: 47, Issue:5 Topics: Acetylcysteine; Animals; Asthma; Female; Glutathione; I-kappa B Kinase; Lung; Malondialdehyde; Mice; Mice, Inbred C57BL; Mice, Obese; NF-kappa B; NF-KappaB Inhibitor alpha; Obesity; Ovalbumin; Oxidative Stress; Phosphorylation; Signal Transduction; Tumor Necrosis Factor-alpha	2020
Legacy Effect of Antioxidant N-acetylcysteine in Cellular Senescence of Diet-induced Obesity Mice. Current molecular medicine, 2021, Volume: 21, Issue:6 Topics: Acetylcysteine; Animals; Antioxidants; Cellular Senescence; Diet, High-Fat; Insulin Resistance; Male; Mice; Obesity	2021
Postprandial triglyceride-rich lipoproteins-induced premature senescence of adipose-derived mesenchymal stem cells via the SIRT1/p53/Ac-p53/p21 axis through oxidative mechanism. Aging, 2020, 12-09, Volume: 12, Issue:24 Topics: Acetylation; Acetylcysteine; Adipogenesis; Animals; beta-Galactosidase; Cell Proliferation; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Down-Regulation; Inflammation; Lipoproteins; Mesenchymal Stem Cells; Mice; Obesity; Oxidative Stress; Postprandial Period; Reactive Oxygen Species; Sirtuin 1; Subcutaneous Fat; Triglycerides; Tumor Suppressor Protein p53; Up-Regulation	2020
Evaluation of Dosing Strategies of N-acetylcysteine for Acetaminophen Toxicity in Patients Greater than 100 Kilograms: Should the Dosage Cap Be Used? Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2021, Volume: 17, Issue:3 Topics: Acetaminophen; Acetylcysteine; Adult; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Free Radical Scavengers; Humans; Male; Middle Aged; Obesity; Retrospective Studies	2021
N-acetylcysteine reduces addiction-like behaviour towards high-fat high-sugar food in diet-induced obese rats. The European journal of neuroscience, 2021, Volume: 54, Issue:3 Topics: Acetylcysteine; Animals; Diet, High-Fat; Male; Obesity; Rats; Rats, Sprague-Dawley; Sugars	2021
Obesity-induced astrocyte dysfunction impairs heterosynaptic plasticity in the orbitofrontal cortex. Cell reports, 2021, 08-17, Volume: 36, Issue:7 Topics: Acetylcysteine; Animals; Astrocytes; Biological Transport; Diet; Endocannabinoids; GABAergic Neurons; Glutamic Acid; Homeostasis; Hypertrophy; Male; Neural Inhibition; Neuronal Plasticity; Obesity; Prefrontal Cortex; Rats, Long-Evans; Synapses; Synaptic Transmission	2021
Being overweight or obese as a risk factor for acute liver injury secondary to acute acetaminophen overdose. Pharmacoepidemiology and drug safety, 2018, Volume: 27, Issue:1 Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Body Mass Index; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Drug Overdose; Female; Follow-Up Studies; Humans; Incidence; Male; Middle Aged; Obesity; Retrospective Studies; Risk Assessment; Risk Factors; Thailand; Young Adult	2018
Early intervention of N-acetylcysteine better improves insulin resistance in diet-induced obesity mice. Free radical research, 2018, Volume: 52, Issue:11-12 Topics: Acetylcysteine; Animals; Diet; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mitochondria; Obesity; Reactive Oxygen Species; Secondary Prevention	2018
N-Acetyl-l-Cysteine treatment efficiently prevented pre-diabetes and inflamed-dysmetabolic liver development in hypothalamic obese rats. Life sciences, 2018, Apr-15, Volume: 199 Topics: Acetylcysteine; Animals; Antioxidants; Blood Glucose; Hypothalamus; Insulin Resistance; Liver; Male; Obesity; Oxidative Stress; Prediabetic State; Rats; Rats, Wistar; Treatment Outcome	2018
Deficiency of NPGPx, an oxidative stress sensor, leads to obesity in mice and human. EMBO molecular medicine, 2013, Volume: 5, Issue:8 Topics: Acetylcysteine; Adipocytes; Animals; Antioxidants; Body Mass Index; Carrier Proteins; CCAAT-Enhancer-Binding Protein-beta; Female; Gene Expression Regulation; Glutathione Peroxidase; Humans; Male; Mice; Mice, Knockout; Obesity; Oxidative Stress; Peroxidases; Phenotype; Polymorphism, Single Nucleotide; Reactive Oxygen Species	2013
N-acetylcysteine supplementation decreases osteoclast differentiation and increases bone mass in mice fed a high-fat diet. The Journal of nutrition, 2014, Volume: 144, Issue:3 Topics: Acetylcysteine; Animals; Antioxidants; Body Weight; Bone Density; Bone Resorption; Cell Differentiation; Cell Line, Tumor; Diet, High-Fat; Dietary Fats; Dietary Supplements; Disease Models, Animal; Glutathione; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Osteoclasts	2014
N-acetylcysteine Protects Mice from High Fat Diet-induced Metabolic Disorders. Pharmaceutical research, 2016, Volume: 33, Issue:8 Topics: Acetylcysteine; Animals; Blood Glucose; Diet, High-Fat; Insulin; Male; Metabolic Diseases; Mice; Mice, Inbred C57BL; Obesity	2016
Dysregulation of adipose glutathione peroxidase 3 in obesity contributes to local and systemic oxidative stress. Molecular endocrinology (Baltimore, Md.), 2008, Volume: 22, Issue:9 Topics: 3T3-L1 Cells; Acetylcysteine; Adipose Tissue; Animals; Antioxidants; Base Sequence; Gene Expression Regulation, Enzymologic; Glutathione Peroxidase; Humans; Hypoxia; Kidney; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Oxidative Stress; PPAR gamma; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Tumor Necrosis Factor-alpha	2008
Oxidative stress regulates adipocyte apolipoprotein e and suppresses its expression in obesity. Diabetes, 2008, Volume: 57, Issue:11 Topics: 3T3-L1 Cells; Acetylcysteine; Adipocytes; Animals; Apolipoproteins E; Blotting, Western; Cells, Cultured; Gene Expression; Hydrogen Peroxide; I-kappa B Proteins; Male; Mice; Mice, Inbred C57BL; NF-KappaB Inhibitor alpha; Obesity; Oxidative Stress; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger	2008
N-acetylcysteine in high-sucrose diet-induced obesity: energy expenditure and metabolic shifting for cardiac health. Pharmacological research, 2009, Volume: 59, Issue:1 Topics: Acetylcysteine; Animals; Energy Metabolism; Heart; Male; Myocardium; Obesity; Oxygen Consumption; Rats; Rats, Wistar; Sucrose; Triglycerides	2009
Reactive oxygen species enhance insulin sensitivity. Cell metabolism, 2009, Volume: 10, Issue:4 Topics: Acetylcysteine; Animals; Antioxidants; Cells, Cultured; Energy Metabolism; Female; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Insulin; Insulin Resistance; Male; Mice; Mice, Knockout; Motor Activity; Obesity; Oxidation-Reduction; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Reactive Oxygen Species; Signal Transduction	2009
A novel cystine based antioxidant attenuates oxidative stress and hepatic steatosis in diet-induced obese mice. Experimental and molecular pathology, 2011, Volume: 91, Issue:1 Topics: Acetylcysteine; Animals; Apolipoproteins E; bcl-2-Associated X Protein; Dietary Fats; Disease Models, Animal; Drug Therapy, Combination; Fatty Liver; Free Radical Scavengers; Hepatocytes; Lipogenesis; Male; MAP Kinase Kinase 4; Mice; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-bcl-2; Selenomethionine	2011
Reactive oxygen species facilitate translocation of hormone sensitive lipase to the lipid droplet during lipolysis in human differentiated adipocytes. PloS one, 2012, Volume: 7, Issue:4 Topics: Acetylcysteine; Adipocytes; Adipose Tissue; Adult; Antioxidants; Biphenyl Compounds; Colforsin; Female; Humans; Lipids; Lipolysis; Middle Aged; Obesity; Onium Compounds; Phosphorylation; Primary Cell Culture; Protein Transport; Reactive Oxygen Species; Resveratrol; Serine; Signal Transduction; Sterol Esterase; Stilbenes	2012
Platelet resistance to the antiaggregating effect of N-acetyl-L-cysteine in obese, insulin-resistant subjects. Thrombosis research, 2003, Apr-15, Volume: 110, Issue:1 Topics: Acetylcysteine; Adenosine Diphosphate; Adult; Amifostine; Antioxidants; Collagen; Cyclic GMP; Drug Resistance; Female; Free Radical Scavengers; Humans; Insulin Resistance; Male; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Nitroprusside; Obesity; Platelet Aggregation; Platelet Aggregation Inhibitors; Superoxide Dismutase	2003
Free fatty acid-induced reduction in glucose-stimulated insulin secretion: evidence for a role of oxidative stress in vitro and in vivo. Diabetes, 2007, Volume: 56, Issue:12 Topics: Acetylcysteine; Animals; Antioxidants; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Glucose; Infusions, Intravenous; Insulin; Insulin Secretion; Obesity; Oleic Acid; Oxidative Stress; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Taurine	2007
Suppression of phosphoenolpyruvate carboxykinase gene expression by reduced endogenous glutathione level. Biochimica et biophysica acta, 2007, Volume: 1772, Issue:10 Topics: Acetylcysteine; Aging; Animals; Cell Line, Tumor; Diabetes Mellitus; Dithiothreitol; Energy Metabolism; Enzyme Inhibitors; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Gluconeogenesis; Glutathione; Hepatocytes; Homeostasis; Male; Obesity; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Phosphoenolpyruvate Carboxykinase (ATP); Rats; Rats, Sprague-Dawley; RNA, Messenger	2007
Oral taurine but not N-acetylcysteine ameliorates NEFA-induced impairment in insulin sensitivity and beta cell function in obese and overweight, non-diabetic men. Diabetologia, 2008, Volume: 51, Issue:1 Topics: Acetylcysteine; Administration, Oral; Adult; Diabetes Mellitus; Fatty Acids, Nonesterified; Free Radical Scavengers; Humans; Insulin; Insulin-Secreting Cells; Lipids; Male; Middle Aged; Obesity; Overweight; Taurine	2008