Compounds > acetylcysteine

acetylcysteine and Non-alcoholic Fatty Liver Disease

acetylcysteine has been researched along with Non-alcoholic Fatty Liver Disease in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (64.29)24.3611
2020's5 (35.71)2.80

Authors

AuthorsStudies
Albadr, NA; Almasri, SA; Aloud, AA; Alshammari, GM; Alwadani, AH; Yahya, MA1
Cotrim, HP; Oliveira, CP; Parise, ER; Salgado, ALA; Siqueira, ACG; Stefano, JT1
Adiels, M; Arif, M; Benfeitas, R; Bergh, PO; Bidkhori, G; Bjornson, E; Borén, J; Bosley, J; Juszczak, K; Kim, JT; Kim, W; Lovric, A; Mardinoglu, A; Marschall, HU; Nielsen, J; Ozcan, M; Ståhlman, M; Taskinen, MR; Tebani, A; Turkez, H; Uhlén, M; Zhang, C1
Chen, YJ; Huang, LT; Lin, IC; Sheen, JM; Tain, YL; Tiao, MM; Tsai, CC; Wang, PW; Yu, HR1
Azevedo Cerqueira, AR; Chaves Cayuela, N; Frasson de Souza Montero, E; Jacysyn, JF; Kiyomi Koike, M; Massazo Utiyama, E; Pereira Costa, SK; Picanço Diniz-Júnior, JA; Rasslan, R1
Baum, SJ; Chakravarthy, MV; Chera, H; Gunn, NT; Harrison, SA; Kohli, A; Koziel, MJ; Patil, R; Younes, ZH; Zhao, J1
Jiang, X; Ke, Y; Liu, S; Pan, X; Shao, Y; Shi, T; Sun, J; Xi, J; Yang, X; Zhang, J; Zhou, H; Zhuang, R1
Feng, J; Ge, CX; Gu, TT; Hu, LF; Huang, P; Li, Q; Lou, DS; Qin, YT; Tan, J; Xu, MX1
Carrilho, FJ; Cogliati, B; de Oliveira, CP; de Oliveira, MG; de Souza, GF; Ferreira Alves, VA; Lima, FR; Mazo, DF; Pereira, IV; Rabelo, F; Stefano, JT1
An, W; Jiang, S; Li, Y; Yu, H; Zhang, J1
Fujii, H; Hai, H; Kawada, N; Kubo, S; Matsumoto, Y; Morita, T; Motoyama, H; Suoh, M; Takemura, S; Tamori, A; Thuy, le TT; Thuy, TT; Urahara, Y; Yoshizato, K1
Abdel-Latif, HA; Ali, MH; Messiha, BA1
Diehl, AM; Jewell, ML; Kruger, L; Machado, MV; Michelotti, GA; Moylan, CA; Pereira, Tde A; Xie, G1
Crum, A; Crum, AC; French, SW; Kim, H; Kim, HJ; Norris, KC; Rajavashisth, TB; Shen, R; Sinha-Hikim, AP; Sinha-Hikim, I; Vaziri, ND1

Trials

2 trial(s) available for acetylcysteine and Non-alcoholic Fatty Liver Disease

ArticleYear
N-ACETYLCYSTEINE AND/OR URSODEOXYCHOLIC ACID ASSOCIATED WITH METFORMIN IN NON-ALCOHOLIC STEATOHEPATITIS: AN OPEN-LABEL MULTICENTER RANDOMIZED CONTROLLED TRIAL.
    Arquivos de gastroenterologia, 2019, Aug-13, Volume: 56, Issue:2

    Topics: Acetylcysteine; Adolescent; Adult; Aged; Drug Therapy, Combination; Female; Humans; Male; Metformin; Middle Aged; Non-alcoholic Fatty Liver Disease; Treatment Outcome; Ursodeoxycholic Acid; Young Adult

2019
Safety, Tolerability, and Biologic Activity of AXA1125 and AXA1957 in Subjects With Nonalcoholic Fatty Liver Disease.
    The American journal of gastroenterology, 2021, 12-01, Volume: 116, Issue:12

    Topics: Acetylcysteine; Administration, Oral; Arginine; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Combinations; Drug Tolerance; Female; Glutamine; Humans; Isoleucine; Leucine; Liver; Magnetic Resonance Imaging; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Single-Blind Method; Treatment Outcome; Valine

2021

Other Studies

12 other study(ies) available for acetylcysteine and Non-alcoholic Fatty Liver Disease

ArticleYear
The Synergistic Protective Effect of γ-Oryzanol (OZ) and N-Acetylcysteine (NAC) against Experimentally Induced NAFLD in Rats Entails Hypoglycemic, Antioxidant, and PPARα Stimulatory Effects.
    Nutrients, 2022, Dec-26, Volume: 15, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Diet, High-Fat; Glucose; Hypoglycemic Agents; Liver; Male; Non-alcoholic Fatty Liver Disease; PPAR alpha; Rats

2022
The acute effect of metabolic cofactor supplementation: a potential therapeutic strategy against non-alcoholic fatty liver disease.
    Molecular systems biology, 2020, Volume: 16, Issue:4

    Topics: Acetylcysteine; Adult; Animals; Carnitine; Dietary Supplements; Drug Therapy, Combination; Healthy Volunteers; Humans; Male; Metabolomics; Models, Animal; Niacinamide; Non-alcoholic Fatty Liver Disease; Precision Medicine; Pyridinium Compounds; Rats; Serine

2020
Long term N-acetylcysteine administration rescues liver steatosis via endoplasmic reticulum stress with unfolded protein response in mice.
    Lipids in health and disease, 2020, May-25, Volume: 19, Issue:1

    Topics: Acetylcysteine; Activating Transcription Factor 4; Animals; Antioxidants; Apoptosis; Chaperonin 60; Diet, High-Fat; Endoplasmic Reticulum Stress; Enoyl-CoA Hydratase; Fatty Liver; Gene Expression Regulation; HSP70 Heat-Shock Proteins; Liver; Male; Mice; Mice, Inbred C57BL; Mitochondrial Proteins; Non-alcoholic Fatty Liver Disease; Unfolded Protein Response

2020
    International journal of molecular sciences, 2020, Jun-09, Volume: 21, Issue:11

    Topics: Acetylcysteine; Alanine Transaminase; Animals; Antioxidants; Apoptosis; Aspartate Aminotransferases; Cell Death; Cytokines; Liver; Mice, Inbred C57BL; NF-E2-Related Factor 2; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Reperfusion Injury

2020
Activated carbon N-acetylcysteine microcapsule protects against nonalcoholic fatty liver disease in young rats via activating telomerase and inhibiting apoptosis.
    PloS one, 2018, Volume: 13, Issue:1

    Topics: Acetylcysteine; Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Enzyme Activation; Glucose; Glucose Tolerance Test; Homeostasis; Male; Non-alcoholic Fatty Liver Disease; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Telomerase

2018
Prolonged PM2.5 exposure elevates risk of oxidative stress-driven nonalcoholic fatty liver disease by triggering increase of dyslipidemia.
    Free radical biology & medicine, 2019, Volume: 130

    Topics: Acetylcysteine; Air Pollutants; Animals; Dyslipidemias; Hepatocytes; Humans; Inflammation; Insulin Resistance; Lipid Metabolism; Liver; Metabolic Syndrome; Mice; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Particulate Matter; Pyrrolidines; Signal Transduction; Thiocarbamates

2019
S-nitroso-N-acetylcysteine attenuates liver fibrosis in experimental nonalcoholic steatohepatitis.
    Drug design, development and therapy, 2013, Volume: 7

    Topics: Acetylcysteine; Animals; Fatty Liver; Immunohistochemistry; Liver Cirrhosis, Experimental; Matrix Metalloproteinase 13; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Rats; Rats, Sprague-Dawley

2013
Enhanced endoplasmic reticulum SERCA activity by overexpression of hepatic stimulator substance gene prevents hepatic cells from ER stress-induced apoptosis.
    American journal of physiology. Cell physiology, 2014, Feb-01, Volume: 306, Issue:3

    Topics: Acetylcysteine; Apoptosis; Calcium; Cell Line, Tumor; Cell Survival; Down-Regulation; eIF-2 Kinase; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Eukaryotic Initiation Factor-2; Fatty Acids, Nonesterified; Fatty Liver; Heat-Shock Proteins; Hepatocytes; Humans; Intercellular Signaling Peptides and Proteins; Liver; Non-alcoholic Fatty Liver Disease; Peptides; Reactive Oxygen Species; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Signal Transduction; Sterol Regulatory Element Binding Proteins; Transcription Factor CHOP; Transfection

2014
Cytoglobin deficiency promotes liver cancer development from hepatosteatosis through activation of the oxidative stress pathway.
    The American journal of pathology, 2015, Volume: 185, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Cytoglobin; Diet; Globins; Hepatic Stellate Cells; Humans; Inflammation; Liver; Liver Cirrhosis; Liver Neoplasms; Macrophages; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Oxidation-Reduction; Oxidative Stress; Precancerous Conditions

2015
Protective effect of ursodeoxycholic acid, resveratrol, and N-acetylcysteine on nonalcoholic fatty liver disease in rats.
    Pharmaceutical biology, 2016, Volume: 54, Issue:7

    Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Choline Deficiency; Cytoprotection; Disease Models, Animal; Hypolipidemic Agents; Lipids; Liver; Male; Methionine; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Rats, Wistar; Resveratrol; Stilbenes; Ursodeoxycholic Acid

2016
Vitamin B5 and N-Acetylcysteine in Nonalcoholic Steatohepatitis: A Preclinical Study in a Dietary Mouse Model.
    Digestive diseases and sciences, 2016, Volume: 61, Issue:1

    Topics: Acetylcysteine; Acyl Coenzyme A; Animals; Apoptosis; Caspase 2; Choline Deficiency; Diet, Western; Disease Models, Animal; Liver; Liver Cirrhosis; Male; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor); Vitamin B Complex

2016
A novel cystine based antioxidant attenuates oxidative stress and hepatic steatosis in diet-induced obese mice.
    Experimental and molecular pathology, 2011, Volume: 91, Issue:1

    Topics: Acetylcysteine; Animals; Apolipoproteins E; bcl-2-Associated X Protein; Dietary Fats; Disease Models, Animal; Drug Therapy, Combination; Fatty Liver; Free Radical Scavengers; Hepatocytes; Lipogenesis; Male; MAP Kinase Kinase 4; Mice; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-bcl-2; Selenomethionine

2011