acetylcysteine and Neoplasm Metastasis

acetylcysteine has been researched along with Neoplasm Metastasis in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (9.52)18.2507
2000's11 (52.38)29.6817
2010's7 (33.33)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Carvalho-Kelly, LF; Cosentino-Gomes, D; Cunha Nascimento, MT; Dick, CF; Lacerda-Abreu, MA; Meyer-Fernandes, JR; Rocco-Machado, N; Rocha-Vieira, TC; Russo-Abrahão, T1
Chen, XP; Lu, JJ; Luo, WW; Wang, YT; Zhao, WW1
Akula, MK; Akyürek, LM; Bergo, MO; Dalin, MG; Ibrahim, MX; Karlsson, C; Le Gal, K; Lindahl, P; Nilsson, J; Sayin, VI; Wiel, C1
Guo, Q; Kang, M; Li, B; Li, C; Qin, W; Wu, Y; Yang, B; Yang, H; Zhang, B; Zhang, Y; Zheng, W1
He, JD; Li, SP; Shen, ZY; Wang, CY; Wang, Z; Xu, HX; Xu, YJ; Yao, Z; Yu, Y; Zhang, HM; Zhang, JJ; Zhang, RX1
Blank, V; Fink, D; Gutsche, K; Leo, C; Randi, EB; Scholz, CC; Wenger, RH1
Cheng, PF; Ma, HX; Wang, CJ; Wang, JH; Xie, SQ; Zhao, J1
Du, J; Gu, L; Hu, Z; Lu, X; Sun, C; Yang, Y; Zheng, D; Zhu, Y1
Li, Y; Liu, B; Wu, H; Wu, X; Xu, K; Yan, H; Zhou, Q; Zhu, Y1
Chang, C; Chapman, PB; Fleisher, M; Hwu, WJ; Krown, SE; Livingston, PO; Pinto, JT; Williams, L; Wolchok, JD1
Futakuchi, M; Ogawa, K; Shirai, T; Takahashi, S; Tamano, S1
Agarwal, A; Claffey, KP; Klueh, U; Muñoz-Nájar, U; Shih, SC1
Wong, AS; Zhou, HY1
Hwang, ES; Lee, HJ2
Engel, D; Levovich, I; Makarovsky, I; Nudelman, A; Rephaeli, A; Sochotnikov, S; Tarasenko, I; Tarasenko, N1
Gorospe, M; Kawai, T; Otto, K; Rinker-Schaeffer, CW; Robinson, VL; Shalhav, O1
Akimoto, M; Hayashi, J; Honma, Y; Imanishi, H; Ishikawa, K; Koshikawa, N; Nakada, K; Takenaga, K; Yamaguchi, A1
Albini, A; Bagnasco, M; Balansky, RM; Bennicelli, C; Camoirano, A; Cesarone, CF; D'Agostini, F; De Flora, S; Rovida, A; Scatolini, L1
Goldman, Y; Peled, A; Shinitzky, M1
Akedo, H; Horai, T; Imamura, F; Mukai, M; Shinkai, K1

Reviews

1 review(s) available for acetylcysteine and Neoplasm Metastasis

ArticleYear
Chemopreventive properties and mechanisms of N-Acetylcysteine. The experimental background.
    Journal of cellular biochemistry. Supplement, 1995, Volume: 22

    Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Biomarkers; Cricetinae; Cytoplasm; Humans; Inactivation, Metabolic; Mice; Mutagenicity Tests; Neoplasm Invasiveness; Neoplasm Metastasis; Rats

1995

Trials

1 trial(s) available for acetylcysteine and Neoplasm Metastasis

ArticleYear
Phase I trial of high dose paracetamol and carmustine in patients with metastatic melanoma.
    Melanoma research, 2003, Volume: 13, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antineoplastic Agents, Alkylating; Carmustine; Cohort Studies; Dose-Response Relationship, Drug; Female; Free Radical Scavengers; Glutathione; Glutathione Reductase; Humans; Leukocytes, Mononuclear; Liver Neoplasms; Lymphatic Metastasis; Male; Maximum Tolerated Dose; Melanoma; Neoplasm Metastasis; Skin Neoplasms; Time Factors

2003

Other Studies

19 other study(ies) available for acetylcysteine and Neoplasm Metastasis

ArticleYear
Hydrogen Peroxide Generation as an Underlying Response to High Extracellular Inorganic Phosphate (Pi) in Breast Cancer Cells.
    International journal of molecular sciences, 2021, Sep-18, Volume: 22, Issue:18

    Topics: Acetylcysteine; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Survival; Epithelial-Mesenchymal Transition; Female; Humans; Hydrogen Peroxide; MCF-7 Cells; Membrane Potential, Mitochondrial; NADPH Oxidases; Neoplasm Metastasis; Oxygen Consumption; Phosphates; Protein Kinase C; Reactive Oxygen Species

2021
Cucurbitacin B suppresses metastasis mediated by reactive oxygen species (ROS) via focal adhesion kinase (FAK) in breast cancer MDA-MB-231 cells.
    Chinese journal of natural medicines, 2018, Volume: 16, Issue:1

    Topics: Acetylcysteine; Antineoplastic Agents; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Collagen Type I; Dose-Response Relationship, Drug; Down-Regulation; Female; Fibronectins; Focal Adhesion Kinase 1; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Paxillin; Phosphorylation; Reactive Oxygen Species; Triterpenes

2018
Antioxidants can increase melanoma metastasis in mice.
    Science translational medicine, 2015, Oct-07, Volume: 7, Issue:308

    Topics: Acetylcysteine; Animals; Antioxidants; Cell Line, Tumor; Chromans; Dietary Supplements; Disease Models, Animal; Glutathione; Humans; Male; Melanoma; Mice; Neoplasm Metastasis

2015
Inhibition of autophagy promotes metastasis and glycolysis by inducing ROS in gastric cancer cells.
    Oncotarget, 2015, Nov-24, Volume: 6, Issue:37

    Topics: Acetylcysteine; Animals; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Epithelial-Mesenchymal Transition; Free Radical Scavengers; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Membrane Proteins; Mice, Nude; Microscopy, Confocal; Neoplasm Metastasis; Reactive Oxygen Species; RNA Interference; RNAi Therapeutics; Stomach Neoplasms; Transcription Factor RelA; Xenograft Model Antitumor Assays

2015
LncRNA HULC enhances epithelial-mesenchymal transition to promote tumorigenesis and metastasis of hepatocellular carcinoma via the miR-200a-3p/ZEB1 signaling pathway.
    Oncotarget, 2016, Jul-05, Volume: 7, Issue:27

    Topics: Acetylcysteine; Aged; Animals; Apoptosis; Carcinogenesis; Carcinoma, Hepatocellular; Cell Proliferation; Cell Transformation, Neoplastic; Disease Progression; Epithelial-Mesenchymal Transition; Female; Humans; Lentivirus; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Middle Aged; Neoplasm Metastasis; Neoplasm Transplantation; RNA, Long Noncoding; RNA, Small Interfering; Signal Transduction; Zinc Finger E-box-Binding Homeobox 1

2016
Intermittent hypoxia confers pro-metastatic gene expression selectively through NF-κB in inflammatory breast cancer cells.
    Free radical biology & medicine, 2016, Volume: 101

    Topics: Acetylcysteine; Anthracenes; Cell Hypoxia; Cell Line, Tumor; Cyclooxygenase 2; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; Mammary Glands, Human; Matrix Metalloproteinase 9; Neoplasm Metastasis; NF-E2-Related Factor 2; NF-kappa B; NF-KappaB Inhibitor alpha; Nitriles; Oxidative Stress; Oxygen; Phosphorylation; Proto-Oncogene Proteins c-jun; Signal Transduction; Sulfones; Tenascin

2016
Polyamine transporter recognization and antitumor effects of anthracenymethyl homospermidine.
    Toxicology, 2009, Sep-19, Volume: 263, Issue:2-3

    Topics: Acetylcysteine; Animals; Anthracenes; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Line, Tumor; Cytochrome c Group; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression Regulation, Enzymologic; Lung Neoplasms; Matrix Metalloproteinases; Melanoma, Experimental; Membrane Transport Proteins; Mice; Mitochondria; Neoplasm Metastasis; Oxidative Stress; Polyamines; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Spermidine; Xenograft Model Antitumor Assays

2009
Lysophosphatidic acid induces MDA-MB-231 breast cancer cells migration through activation of PI3K/PAK1/ERK signaling.
    PloS one, 2010, Dec-30, Volume: 5, Issue:12

    Topics: Acetylcysteine; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Lysophospholipids; Neoplasm Metastasis; p21-Activated Kinases; Phosphatidylinositol 3-Kinases; Reactive Oxygen Species; Signal Transduction

2010
Mitogen-activated protein kinase mediates the apoptosis of highly metastatic human non-small cell lung cancer cells induced by isothiocyanates.
    The British journal of nutrition, 2011, Volume: 106, Issue:12

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line, Tumor; Cyclin B1; Gene Expression; Humans; Isothiocyanates; Lung Neoplasms; MAP Kinase Signaling System; Neoplasm Metastasis; Transcription Factor AP-1

2011
Suppression of metastasis by nuclear factor kappaB inhibitors in an in vivo lung metastasis model of chemically induced hepatocellular carcinoma.
    Cancer science, 2004, Volume: 95, Issue:1

    Topics: Acetylcysteine; Animals; Aspirin; Blotting, Western; Carcinogens; Diethylnitrosamine; E-Selectin; Enzyme Inhibitors; Free Radical Scavengers; Intercellular Adhesion Molecule-1; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Neoplasm Metastasis; NF-kappa B; Nitrosamines; Pentoxifylline; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vascular Cell Adhesion Molecule-1

2004
N-acetyl-cysteine promotes angiostatin production and vascular collapse in an orthotopic model of breast cancer.
    The American journal of pathology, 2004, Volume: 164, Issue:5

    Topics: Acetylcysteine; Angiostatins; Animals; Antioxidants; Apoptosis; Breast Neoplasms; Cell Division; Cell Line, Tumor; Cell Survival; Chickens; Disease Models, Animal; DNA, Complementary; Endothelial Cells; Free Radical Scavengers; Green Fluorescent Proteins; Humans; In Situ Nick-End Labeling; Luminescent Proteins; Lymphatic Metastasis; Mammary Neoplasms, Animal; Mice; Mice, Nude; Microcirculation; Microscopy, Fluorescence; Models, Biological; Necrosis; Neoplasm Metastasis; Neoplasm Transplantation; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Vascular Endothelial Growth Factor A

2004
Activation of p70S6K induces expression of matrix metalloproteinase 9 associated with hepatocyte growth factor-mediated invasion in human ovarian cancer cells.
    Endocrinology, 2006, Volume: 147, Issue:5

    Topics: Acetylcysteine; Blotting, Western; Cell Line, Tumor; Cell Movement; Down-Regulation; Enzyme Activation; Extracellular Matrix; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Hepatocyte Growth Factor; Humans; Immunoblotting; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Models, Statistical; Neoplasm Invasiveness; Neoplasm Metastasis; Neurons; Ovarian Neoplasms; Phenotype; Phosphatidylinositol 3-Kinases; Phosphorylation; Promoter Regions, Genetic; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Time Factors; Transfection

2006
Phenylethyl isothiocyanate and its N-acetylcysteine conjugate suppress the metastasis of SK-Hep1 human hepatoma cells.
    The Journal of nutritional biochemistry, 2006, Volume: 17, Issue:12

    Topics: Acetylcysteine; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Adhesion; Cell Movement; Drug Screening Assays, Antitumor; Humans; Isothiocyanates; Liver Neoplasms; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Neoplasm Metastasis; Tissue Inhibitor of Metalloproteinase-1; Tumor Cells, Cultured

2006
Allyl isothiocyanate and its N-acetylcysteine conjugate suppress metastasis via inhibition of invasion, migration, and matrix metalloproteinase-2/-9 activities in SK-Hep 1 human hepatoma cells.
    Experimental biology and medicine (Maywood, N.J.), 2006, Volume: 231, Issue:4

    Topics: Acetylcysteine; Brassica; Carcinoma, Hepatocellular; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Isothiocyanates; Liver Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Neoplasm Invasiveness; Neoplasm Metastasis; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2

2006
Novel prodrugs of tegafur that display improved anticancer activity and antiangiogenic properties.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Acetylcysteine; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antioxidants; Astrocytes; Cell Line, Tumor; Cell Survival; Cells, Cultured; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Endothelial Cells; Endothelium, Vascular; Formaldehyde; Histone Acetyltransferases; Humans; Male; Methylation; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Prodrugs; Semicarbazides; Structure-Activity Relationship; Tegafur; Transplantation, Heterologous; Umbilical Cord

2008
Mitogen-activated protein kinase kinase 4/c-Jun NH2-terminal kinase kinase 1 protein expression is subject to translational regulation in prostate cancer cell lines.
    Molecular cancer research : MCR, 2008, Volume: 6, Issue:3

    Topics: Acetylcysteine; Blotting, Northern; Cell Line, Tumor; Cycloheximide; Dactinomycin; Ethanol; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Male; MAP Kinase Kinase 4; Neoplasm Metastasis; Ovarian Neoplasms; Polymerase Chain Reaction; Prostatic Neoplasms; Protein Biosynthesis

2008
ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis.
    Science (New York, N.Y.), 2008, May-02, Volume: 320, Issue:5876

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Cell Line, Tumor; DNA, Mitochondrial; DNA, Neoplasm; Electron Transport Complex I; Free Radical Scavengers; HeLa Cells; Humans; Hybrid Cells; Mice; Mutation; NADH Dehydrogenase; Neoplasm Metastasis; Reactive Oxygen Species

2008
Effective elimination of lung metastases induced by tumor cells treated with hydrostatic pressure and N-acetyl-L-cysteine.
    Cancer research, 2000, Jan-15, Volume: 60, Issue:2

    Topics: Acetylcysteine; Adenosine; Animals; CD4 Antigens; CD8 Antigens; Female; Humans; Hydrostatic Pressure; Hypersensitivity, Delayed; Lung; Lung Neoplasms; Lymphocyte Culture Test, Mixed; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasm Metastasis; Spleen

2000
Potentiation of invasive capacity of rat ascites hepatoma cells by adriamycin.
    Cancer research, 1990, Apr-01, Volume: 50, Issue:7

    Topics: Acetylcysteine; Animals; Ascites; Cell Survival; Free Radicals; Liver Neoplasms, Experimental; Neoplasm Metastasis; Rats

1990