Compounds > acetylcysteine

acetylcysteine and Myocardial Ischemia

acetylcysteine has been researched along with Myocardial Ischemia in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (13.64)18.2507
2000's12 (54.55)29.6817
2010's7 (31.82)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fei, Q; Liu, K; Liu, M; Wang, H; Wang, K; Wang, N; Xiao, H; Xiao, X; Zhang, H; Zou, J1
Apaijai, N; Chattipakorn, K; Chattipakorn, N; Chattipakorn, SC; Jaiwongkum, T; Palee, S; Pratchayasakul, W; Sivasinprasasn, S1
Avcı, B; Çavun, S; Savcı, V; Şentürk, T; Serdar, Z; Yermezler, A1
Dasgupta, C; Huang, X; Li, Y; Wang, L; Xiao, D; Zhang, L1
Guliaev, AM; Lishmanov, IuB; Rybal'chenko, EV; Vesnina, ZhV1
Cha, MJ; Chang, W; Choi, EJ; Chung, N; Ham, O; Hwang, KC; Jang, Y; Kim, IK; Lee, SY; Lim, S; Song, BW; Song, H1
Chen, N; Ko, M1
Andre, L; Cazorla, O; Farah, C; Fauconnier, J; Feillet-Coudray, C; Fouret, G; Lacampagne, A; Meschin, P; Reboul, C; Richard, S1
Adams, J; Ardeshirpour, F; Baldwin, AS; Bellinger, DA; Elliott, PJ; Fischer, TH; McCain, A; Merricks, E; Nichols, TC; Pien, C; Pye, J1
Angelos, MG; Klawitter, PF; Palmer, BS; Reiser, PJ1
Adamy, C; Bourin, MC; Candiani, G; Defer, N; Hittinger, L; Kirsch, M; Le Corvoisier, P; Pavoine, C; Pecker, E; Su, JB; Vermes, E1
Divald, A; Powell, SR1
Alver, A; Kalyoncu, NI; Karahan, SC; Koramaz, I; Ozcan, F; Pulathan, Z; Usta, S; Yaris, E1
Brennan, JP; Davidson, SM; Duchen, MR; Medina, RA; Shattock, MJ; Southworth, R1
Powell, SR1
Kucharská, J; Matejíková, J; Pancza, D; Ravingerová, T1
Chen, W; Gabel, S; Murphy, E; Steenbergen, C1
Boily, MJ; Brunet, J; Cordeau, S; Des Rosiers, C1
Hegde, BM; Tripathi, Y1
Garcia-Dorado, D; Hofstaetter, B; Inserte, J; Piper, HM; Taimor, G1
Bishopric, NH; Discher, DJ; Hernandez, OM; Webster, KA1
Alam, J; Das, DK; Ho, YS; Maulik, N; Yoshida, T1

Reviews

1 review(s) available for acetylcysteine and Myocardial Ischemia

ArticleYear
Tumor necrosis factor alpha and glutathione interplay in chronic heart failure.
    Archives des maladies du coeur et des vaisseaux, 2005, Volume: 98, Issue:9

    Topics: Acetylcysteine; Animals; Cardiotonic Agents; Glutathione; Heart Failure; Humans; Myocardial Contraction; Myocardial Ischemia; Tumor Necrosis Factor-alpha

2005

Trials

2 trial(s) available for acetylcysteine and Myocardial Ischemia

ArticleYear
[Radionuclide renoscintigraphy for the evaluation of nephroprotective action of acetylcysteine].
    Klinicheskaia meditsina, 2009, Volume: 87, Issue:10

    Topics: Acetylcysteine; Contrast Media; Coronary Angiography; Female; Follow-Up Studies; Free Radical Scavengers; Humans; Injections, Intravenous; Iohexol; Male; Middle Aged; Myocardial Ischemia; Radionuclide Imaging; Radiopharmaceuticals; Renal Insufficiency; Technetium Tc 99m Pentetate; Treatment Outcome

2009
Cardioprotective effect of cold-blood cardioplegia enriched with N-acetylcysteine during coronary artery bypass grafting.
    The Annals of thoracic surgery, 2006, Volume: 81, Issue:2

    Topics: Acetylcysteine; Coronary Artery Bypass; Coronary Artery Disease; Female; Free Radical Scavengers; Heart Arrest, Induced; Hemodynamics; Humans; Hypothermia, Induced; Male; Malondialdehyde; Middle Aged; Myocardial Ischemia; Reperfusion Injury; Treatment Outcome; Troponin I

2006

Other Studies

19 other study(ies) available for acetylcysteine and Myocardial Ischemia

ArticleYear
VEGF-A promotes angiogenesis after acute myocardial infarction through increasing ROS production and enhancing ER stress-mediated autophagy.
    Journal of cellular physiology, 2019, Volume: 234, Issue:10

    Topics: Acetylcysteine; Animals; Autophagy; Beclin-1; Disease Models, Animal; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Mice, Inbred BALB C; Myocardial Infarction; Myocardial Ischemia; Neovascularization, Physiologic; Reactive Oxygen Species; RNA, Small Interfering; Vascular Endothelial Growth Factor A

2019
N-acetylcysteine with low-dose estrogen reduces cardiac ischemia-reperfusion injury.
    The Journal of endocrinology, 2019, Volume: 242, Issue:2

    Topics: Acetylcysteine; Animals; Cardiotonic Agents; Dose-Response Relationship, Drug; Estradiol; Estrogens; Female; Heart Rate; Humans; Mitochondria, Heart; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Ovariectomy; Rats, Wistar

2019
Effective inhibition of cardiomyocyte apoptosis through the combination of trimetazidine and N-acetylcysteine in a rat model of myocardial ischemia and reperfusion injury.
    Atherosclerosis, 2014, Volume: 237, Issue:2

    Topics: Acetylcysteine; Animals; Apoptosis; Blood Pressure; Caspase 3; Cell Death; Coronary Vessels; Disease Models, Animal; Fatty Acids; Glucose; Glutathione; Inflammation; Male; Malondialdehyde; Myocardial Ischemia; Myocardium; Myocytes, Cardiac; Oxidative Stress; Oxygen; Rats; Rats, Wistar; Reperfusion Injury; S100 Calcium Binding Protein beta Subunit; Trimetazidine

2014
Protective Effect of Antenatal Antioxidant on Nicotine-Induced Heart Ischemia-Sensitive Phenotype in Rat Offspring.
    PloS one, 2016, Volume: 11, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Coronary Circulation; Disease Susceptibility; Drug Evaluation, Preclinical; Female; Fetus; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Infusion Pumps, Implantable; Male; Models, Biological; Myocardial Ischemia; Myocardial Reperfusion Injury; Nicotine; Oxidative Stress; Phenotype; Phosphorylation; Pregnancy; Prenatal Exposure Delayed Effects; Protein Kinase C-epsilon; Protein Processing, Post-Translational; Random Allocation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Recovery of Function; Ventricular Dysfunction, Left

2016
Reactive oxygen species inhibit adhesion of mesenchymal stem cells implanted into ischemic myocardium via interference of focal adhesion complex.
    Stem cells (Dayton, Ohio), 2010, Mar-31, Volume: 28, Issue:3

    Topics: Acetylcysteine; Animals; Cell Adhesion; Cell Adhesion Molecules; Cell Differentiation; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Focal Adhesion Kinase 1; Focal Adhesions; Free Radical Scavengers; Gene Knock-In Techniques; Graft Survival; Hydrogen Peroxide; Integrins; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Myocardial Ischemia; Oxidants; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Regeneration; src-Family Kinases

2010
Schisandrin B-induced glutathione antioxidant response and cardioprotection are mediated by reactive oxidant species production in rat hearts.
    Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:5

    Topics: Acetylcysteine; alpha-Tocopherol; Animals; Antioxidants; Cardiovascular Agents; Cyclooctanes; Cytochrome P-450 Enzyme System; Drugs, Chinese Herbal; Female; Glutathione; Lignans; Microsomes; Mitochondria; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; NADP; Oxidation-Reduction; Phytotherapy; Polycyclic Compounds; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Schisandra

2010
Subendocardial increase in reactive oxygen species production affects regional contractile function in ischemic heart failure.
    Antioxidants & redox signaling, 2013, Mar-20, Volume: 18, Issue:9

    Topics: Acetylcysteine; Animals; Antioxidants; Calcium; Catalase; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Cyclic AMP-Dependent Protein Kinases; Heart Failure; Lipid Peroxidation; Male; Mitochondria, Heart; Myocardial Contraction; Myocardial Ischemia; Myocytes, Cardiac; Myofibrils; Oxidative Stress; Phosphorylation; Protein Processing, Post-Translational; Random Allocation; Rats; Rats, Wistar; Reactive Oxygen Species; Recombinant Proteins; Superoxide Dismutase

2013
Proteasome inhibition ablates activation of NF-kappa B in myocardial reperfusion and reduces reperfusion injury.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 284, Issue:3

    Topics: Acetylcysteine; Animals; Creatine Kinase; Creatine Kinase, MB Form; Cysteine Endopeptidases; Disease Models, Animal; Enzyme Inhibitors; Female; Isoenzymes; Male; Multienzyme Complexes; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; NF-kappa B; Proteasome Endopeptidase Complex; Swine; Troponin I

2003
Degradation of rat cardiac troponin I during ischemia independent of reperfusion.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 287, Issue:3

    Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; Animals; Antioxidants; Blotting, Western; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Sprague-Dawley; Time Factors; Troponin I

2004
Proteasome mediates removal of proteins oxidized during myocardial ischemia.
    Free radical biology & medicine, 2006, Jan-01, Volume: 40, Issue:1

    Topics: Acetylcysteine; Actins; Animals; Cysteine Proteinase Inhibitors; Heart; Immunoprecipitation; Ischemic Preconditioning, Myocardial; Male; Methylhistidines; Myocardial Ischemia; Oxidation-Reduction; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proteins; Rats; Rats, Sprague-Dawley; Reperfusion; Ubiquitin

2006
Mitochondrial uncoupling, with low concentration FCCP, induces ROS-dependent cardioprotection independent of KATP channel activation.
    Cardiovascular research, 2006, Nov-01, Volume: 72, Issue:2

    Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Decanoic Acids; Dose-Response Relationship, Drug; Free Radical Scavengers; Glyburide; Hydroxy Acids; Ischemic Preconditioning, Myocardial; Magnetic Resonance Spectroscopy; Male; Microscopy, Fluorescence; Mitochondria, Heart; Myocardial Ischemia; Perfusion; Potassium Channels; Rats; Rats, Wistar; Reactive Oxygen Species; Tiopronin; Uncoupling Agents

2006
Proteasome inhibitors in myocardial ischemia, some concerns.
    The Annals of thoracic surgery, 2008, Volume: 85, Issue:4

    Topics: Acetylcysteine; Animals; Disease Models, Animal; Humans; Ischemic Preconditioning, Myocardial; Mice; Myocardial Ischemia; NF-kappa B; Oxidation-Reduction; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Reperfusion Injury; Risk Factors; Sensitivity and Specificity

2008
The effect of antioxidant treatment and NOS inhibition on the incidence of ischemia-induced arrhythmias in the diabetic rat heart.
    Physiological research, 2008, Volume: 57 Suppl 2

    Topics: Acetylcysteine; Adaptation, Physiological; alpha-Tocopherol; Animals; Antioxidants; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Male; Myocardial Ischemia; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Tachycardia, Ventricular; Ubiquinone; Up-Regulation; Ventricular Function, Left

2008
A redox-based mechanism for cardioprotection induced by ischemic preconditioning in perfused rat heart.
    Circulation research, 1995, Volume: 77, Issue:2

    Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Biochemical Phenomena; Biochemistry; Coronary Circulation; Creatine Kinase; Energy Metabolism; Glutathione; Heart; Heart Rate; Hydrogen-Ion Concentration; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Oxidation-Reduction; Perfusion; Rats; Time Factors

1995
Effects of N-acetylcysteine in the rat heart reperfused after low-flow ischemia: evidence for a direct scavenging of hydroxyl radicals and a nitric oxide-dependent increase in coronary flow.
    Free radical biology & medicine, 1995, Volume: 19, Issue:5

    Topics: Acetylcysteine; Animals; Coronary Circulation; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Heart; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Kinetics; L-Lactate Dehydrogenase; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Nitric Oxide; Rats; Rats, Sprague-Dawley; Time Factors

1995
Effect of N-acetylcysteine on myocardial infarct size following ischemia and reperfusion in dogs.
    Indian journal of physiology and pharmacology, 1998, Volume: 42, Issue:1

    Topics: Acetylcysteine; Animals; Blood Pressure; Coronary Vessels; Dogs; Free Radical Scavengers; Glutathione; Lipid Peroxidation; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Superoxide Dismutase

1998
Influence of simulated ischemia on apoptosis induction by oxidative stress in adult cardiomyocytes of rats.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 278, Issue:1

    Topics: Acetylcysteine; Animals; Apoptosis; Cells, Cultured; Free Radical Scavengers; Hydrogen Peroxide; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Oxidants; Oxidative Stress; Phosphocreatine; Rats; Rats, Wistar

2000
Rapid activation of neutral sphingomyelinase by hypoxia-reoxygenation of cardiac myocytes.
    Circulation research, 2000, Feb-04, Volume: 86, Issue:2

    Topics: Acetylcysteine; Animals; Cell Hypoxia; Cells, Cultured; Ceramides; Enzyme Activation; Fibroblasts; Free Radical Scavengers; Hydrogen Peroxide; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Kinetics; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Muscle Fibers, Skeletal; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Oxidants; Oxidative Stress; Oxygen; Rats; Sphingomyelin Phosphodiesterase

2000
H(mox-1) constitutes an adaptive response to effect antioxidant cardioprotection: A study with transgenic mice heterozygous for targeted disruption of the Heme oxygenase-1 gene.
    Circulation, 2001, Mar-27, Volume: 103, Issue:12

    Topics: Acetylcysteine; Animals; Antioxidants; Chromans; Creatine Kinase; Disease Models, Animal; Gene Targeting; Heart; Heart Rate; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Heterozygote; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Malondialdehyde; Membrane Proteins; Mice; Mice, Transgenic; Myocardial Contraction; Myocardial Infarction; Myocardial Ischemia; Myocardium; Reperfusion Injury; Thiourea

2001