acetylcysteine and Machado-Joseph Disease

acetylcysteine has been researched along with Machado-Joseph Disease in 2 studies

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Kanazawa, I; Shibasaki, F; Shoji, S; Yoshida, H; Yoshizawa, T	1
Chai, Y; Koppenhafer, SL; Paulson, HL; Perez, MK; Shoesmith, SJ	1

Other Studies

2 other study(ies) available for acetylcysteine and Machado-Joseph Disease

Article	Year
Chemical chaperones reduce aggregate formation and cell death caused by the truncated Machado-Joseph disease gene product with an expanded polyglutamine stretch. Neurobiology of disease, 2002, Volume: 10, Issue:2 Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Ataxin-3; Cell Line; Cricetinae; Dimethyl Sulfoxide; Glutathione; Glycerol; Humans; Machado-Joseph Disease; Mesocricetus; Methylamines; Nerve Tissue Proteins; Nuclear Proteins; Peptide Fragments; Peptides; Protein Conformation; Protein Folding; Recombinant Fusion Proteins; Repressor Proteins; Transfection	2002
Evidence for proteasome involvement in polyglutamine disease: localization to nuclear inclusions in SCA3/MJD and suppression of polyglutamine aggregation in vitro. Human molecular genetics, 1999, Volume: 8, Issue:4 Topics: Acetylcysteine; Adult; Animals; Ataxin-3; Brain; Brain Chemistry; Cell Line; Cell Nucleus; COS Cells; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; HeLa Cells; Humans; Immunohistochemistry; Inclusion Bodies; Leukemia, Promyelocytic, Acute; Machado-Joseph Disease; Male; Multienzyme Complexes; Mutation; Nerve Tissue Proteins; Nuclear Proteins; Oncogene Proteins; PC12 Cells; Peptides; Proteasome Endopeptidase Complex; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Repressor Proteins	1999

Article

Year

Chemical chaperones reduce aggregate formation and cell death caused by the truncated Machado-Joseph disease gene product with an expanded polyglutamine stretch.

Neurobiology of disease, 2002, Volume: 10, Issue:2

Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Ataxin-3; Cell Line; Cricetinae; Dimethyl Sulfoxide; Glutathione; Glycerol; Humans; Machado-Joseph Disease; Mesocricetus; Methylamines; Nerve Tissue Proteins; Nuclear Proteins; Peptide Fragments; Peptides; Protein Conformation; Protein Folding; Recombinant Fusion Proteins; Repressor Proteins; Transfection

2002

Evidence for proteasome involvement in polyglutamine disease: localization to nuclear inclusions in SCA3/MJD and suppression of polyglutamine aggregation in vitro.

Human molecular genetics, 1999, Volume: 8, Issue:4

Topics: Acetylcysteine; Adult; Animals; Ataxin-3; Brain; Brain Chemistry; Cell Line; Cell Nucleus; COS Cells; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; HeLa Cells; Humans; Immunohistochemistry; Inclusion Bodies; Leukemia, Promyelocytic, Acute; Machado-Joseph Disease; Male; Multienzyme Complexes; Mutation; Nerve Tissue Proteins; Nuclear Proteins; Oncogene Proteins; PC12 Cells; Peptides; Proteasome Endopeptidase Complex; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Repressor Proteins

1999