acetylcysteine and MODS

acetylcysteine has been researched along with MODS in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (25.00)18.2507
2000's12 (42.86)29.6817
2010's7 (25.00)24.3611
2020's2 (7.14)2.80

Authors

AuthorsStudies
Wu, J1
Basile, K; Colaco, CMG; Draper, J; Ferguson, PE1
Koch, A; Streetz, KL; Tacke, F; Trautwein, C1
Bedreag, OH; Cradigati, CA; Dumache, R; Horhat, FG; Luca, L; Papurica, M; Popovici, SE; Rogobete, AF; Sandesc, D; Sarandan, M; Sima, LV; Vernic, C1
Chertoff, J1
Kramer, DJ; Stravitz, RT1
Hou, L; Ji, G; Li, N; Li, S; Lu, Y; Ma, S; Peng, D; Qin, M; Shang, L; Xie, K; Xiong, L1
Andrades, M; Dal-Pizzol, F; de Oliveira, MR; Fonseca Moreira, JC; Ritter, C; Streck, EL1
Bogar, L; Bognar, Z; Csontos, C; Drenkovics, L; Foldi, V; Lantos, J; Rezman, B; Röth, E; Weber, G1
Bogar, L; Csontos, C; Drenkovics, L; Foldi, V; Lantos, J; Rezman, B; Röth, E; Weber, G1
Márton, S; Molnár, Z; Szakmány, T; Tóth, I1
Koszegi, T; Molnar, Z; Szakmany, T1
Marton, S; Molnar, Z; Szakmany, T1
Baue, AE1
Asfar, P; De Backer, D; Meier-Hellmann, A; Radermacher, P; Sakka, SG1
Diltoer, MW; Hendrickx, I; Huyghens, LP; Nguyen, DN; Spapen, HD1
Akinci, SB; Aypar, U; Erden, IA; Kanbak, M1
Chen, HI; Harn, HJ; Hsu, BG; Lee, RP; Yang, FL1
Bewley, J; Bourdeaux, C1
De Dios, I; Manso, MA; Ramudo, L1
Agustí, AG; Bergada, J; Ibañez, J; Jorda, R; Maimó, A; Marse, P; Raurich, JM; Togores, B1
Lowe, D; MacKinnon, KL; Molnar, Z; Shearer, E; Watson, ID1
Azimuddin, K; Ivatury, RR; Porter, JM; Swami, R1
Lowe, D; Molnár, Z; Shearer, E1
Caputi, AP; Costantino, G; Cuzzocrea, S; Mazzon, E1
Vaughan, D; Yanay, O; Zimmerman, JJ1
Ariceta, J; Balén, E; Ferrer, JV; Guerrero, D; Herrera, J; Lera, JM1
Rotstein, OD1

Reviews

7 review(s) available for acetylcysteine and MODS

ArticleYear
Tackle the free radicals damage in COVID-19.
    Nitric oxide : biology and chemistry, 2020, 09-01, Volume: 102

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Azithromycin; Betacoronavirus; Clinical Trials as Topic; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Cytokine Release Syndrome; Drug Therapy, Combination; Free Radicals; Glutathione; Humans; Hydroxychloroquine; Mice; Multiple Organ Failure; NF-E2-Related Factor 2; Nitric Oxide; Orthomyxoviridae Infections; Oxidative Stress; Pandemics; Pneumonia, Viral; Reactive Oxygen Species; SARS-CoV-2; Severe Acute Respiratory Syndrome

2020
[Acute liver failure. Diagnosis and therapy].
    Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2013, Volume: 108, Issue:8

    Topics: Acetylcysteine; Chemical and Drug Induced Liver Injury; Hepatic Encephalopathy; Humans; Liver Failure, Acute; Liver Transplantation; Multiple Organ Failure; Nucleosides; Nucleotides; Organ Dysfunction Scores; Prognosis

2013
N-Acetylcysteine's Role in Sepsis and Potential Benefit in Patients With Microcirculatory Derangements.
    Journal of intensive care medicine, 2018, Volume: 33, Issue:2

    Topics: Acetylcysteine; Acidosis, Lactic; Free Radical Scavengers; Humans; Microcirculation; Mortality; Multiple Organ Failure; Regional Blood Flow; Sepsis; Vasodilation

2018
Management of acute liver failure.
    Nature reviews. Gastroenterology & hepatology, 2009, Volume: 6, Issue:9

    Topics: Acetylcysteine; Antiviral Agents; Hepatitis, Viral, Human; Humans; Liver Failure, Acute; Liver Transplantation; Multiple Organ Failure

2009
Clinical review: influence of vasoactive and other therapies on intestinal and hepatic circulations in patients with septic shock.
    Critical care (London, England), 2004, Volume: 8, Issue:3

    Topics: Acetylcysteine; Fluid Therapy; Hemodynamics; Humans; Intestinal Mucosa; Liver; Multiple Organ Failure; Oxygen; Respiration, Artificial; Shock, Septic; Splanchnic Circulation; Vasoconstrictor Agents

2004
Deciphering the oxyradical inflammation Rosetta stone: O2*-NO*, OONO-, polymorphonuclear neutrophils, poly(ADP-ribose) synthetase, systemic inflammatory response syndrome, and multiple organ dysfunction syndrome.
    Critical care medicine, 1999, Volume: 27, Issue:8

    Topics: Acetylcysteine; Free Radical Scavengers; Humans; Inflammation; Multiple Organ Failure; Neutrophils; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Systemic Inflammatory Response Syndrome

1999
Oxidants and antioxidant therapy.
    Critical care clinics, 2001, Volume: 17, Issue:1

    Topics: Acetylcysteine; Antioxidants; Free Radical Scavengers; Humans; Multiple Organ Failure; Reactive Oxygen Species; Superoxide Dismutase

2001

Trials

11 trial(s) available for acetylcysteine and MODS

ArticleYear
Effect of N-acetylcysteine treatment on the expression of leukocyte surface markers after burn injury.
    Burns : journal of the International Society for Burn Injuries, 2011, Volume: 37, Issue:3

    Topics: Acetylcysteine; Aged; Antigens, CD; Antioxidants; Biomarkers; Burns; Female; Flow Cytometry; Humans; Leukocytes; Male; Middle Aged; Multiple Organ Failure; Oxidative Stress; Prospective Studies

2011
Effect of N-acetylcysteine treatment on oxidative stress and inflammation after severe burn.
    Burns : journal of the International Society for Burn Injuries, 2012, Volume: 38, Issue:3

    Topics: Acetylcysteine; Adult; Aged; Antioxidants; Biomarkers; Burns; Catalase; Cytokines; Female; Free Radical Scavengers; Glutathione; Humans; Leukocyte Count; Male; Malondialdehyde; Middle Aged; Multiple Organ Failure; Oxidative Stress; Peroxidase; Prospective Studies; Superoxide Dismutase; Systemic Inflammatory Response Syndrome

2012
[Effect of prophylactic N-acetylcysteine on postoperative organ dysfunction and inflammatory markers after major abdominal surgery for cancer. Prospective, randomized, double-blind, placebo-controlled clinical trial].
    Magyar sebeszet, 2002, Volume: 55, Issue:6

    Topics: Abdominal Neoplasms; Acetylcysteine; Aged; Albuminuria; Biomarkers; C-Reactive Protein; Calcitonin; Calcitonin Gene-Related Peptide; Critical Care; Double-Blind Method; Female; Humans; Inflammation; Infusions, Intravenous; Length of Stay; Male; Middle Aged; Multiple Organ Failure; Prospective Studies; Protein Precursors; Respiration, Artificial; Treatment Outcome

2002
Prophylactic N-acetylcysteine decreases serum CRP but not PCT levels and microalbuminuria following major abdominal surgery. A prospective, randomised, double-blinded, placebo-controlled clinical trial.
    Intensive care medicine, 2003, Volume: 29, Issue:5

    Topics: Abdomen; Acetylcysteine; Aged; Albuminuria; C-Reactive Protein; Calcitonin; Calcitonin Gene-Related Peptide; Double-Blind Method; Female; Free Radical Scavengers; Humans; Intensive Care Units; Male; Middle Aged; Multiple Organ Failure; Postoperative Period; Protein Precursors; Systemic Inflammatory Response Syndrome

2003
Lack of effect of prophylactic N-acetylcysteine on postoperative organ dysfunction following major abdominal tumour surgery: a randomized, placebo-controlled, double-blinded clinical trial.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:3

    Topics: Abdominal Neoplasms; Acetylcysteine; Aged; Double-Blind Method; Female; Free Radical Scavengers; Humans; Male; Middle Aged; Multiple Organ Failure; Postoperative Complications; Treatment Failure

2003
Effects of N-acetylcysteine on microalbuminuria and organ failure in acute severe sepsis: results of a pilot study.
    Chest, 2005, Volume: 127, Issue:4

    Topics: Acetylcysteine; Acute Disease; Adult; Aged; Aged, 80 and over; Albuminuria; Female; Humans; Male; Middle Aged; Multiple Organ Failure; Pilot Projects; Sepsis; Severity of Illness Index

2005
Lack of effect of N-acetylcysteine treatment to ameliorate the progression of multiple organ failure.
    Saudi medical journal, 2005, Volume: 26, Issue:4

    Topics: Acetylcysteine; Adolescent; Adult; Aged; Aged, 80 and over; Disease Progression; Double-Blind Method; Female; Humans; Male; Middle Aged; Multiple Organ Failure; Prospective Studies

2005
Effects of N-acetylcysteine on tissue oxygenation in patients with multiple organ failure and evidence of tissue hypoxia.
    The European respiratory journal, 1997, Volume: 10, Issue:9

    Topics: Acetylcysteine; Adult; Aged; Cross-Over Studies; Hemodynamics; Humans; Hydrogen-Ion Concentration; Hypoxia; Infusions, Intravenous; Middle Aged; Multiple Organ Failure; Oxygen; Oxygen Consumption; Prospective Studies

1997
The effect of N-acetylcysteine on total serum anti-oxidant potential and urinary albumin excretion in critically ill patients.
    Intensive care medicine, 1998, Volume: 24, Issue:3

    Topics: Acetylcysteine; Adult; Aged; Albuminuria; Antioxidants; Cardiotonic Agents; Creatinine; Critical Illness; Double-Blind Method; Female; Free Radical Scavengers; Humans; Length of Stay; Male; Middle Aged; Multiple Organ Failure; Prospective Studies; Respiration, Artificial; Treatment Outcome

1998
Antioxidant therapy in the prevention of organ dysfunction syndrome and infectious complications after trauma: early results of a prospective randomized study.
    The American surgeon, 1999, Volume: 65, Issue:5

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Humans; Infections; Injury Severity Score; Multiple Organ Failure; Prospective Studies; Selenium; Treatment Outcome; Vitamin E; Wounds and Injuries

1999
N-Acetylcysteine treatment to prevent the progression of multisystem organ failure: a prospective, randomized, placebo-controlled study.
    Critical care medicine, 1999, Volume: 27, Issue:6

    Topics: Acetylcysteine; Adult; Aged; APACHE; Critical Care; Double-Blind Method; Female; Free Radical Scavengers; Humans; Infusions, Intravenous; Intensive Care Units; Male; Middle Aged; Multiple Organ Failure; Time Factors

1999

Other Studies

10 other study(ies) available for acetylcysteine and MODS

ArticleYear
Fulminant
    BMJ case reports, 2021, Jan-18, Volume: 14, Issue:1

    Topics: Acetylcysteine; Acidosis; Adult; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Arrhythmias, Cardiac; Bacillus cereus; Blood Coagulation Disorders; Blood Transfusion; Brain Diseases; Continuous Renal Replacement Therapy; Exotoxins; Fatal Outcome; Female; Foodborne Diseases; Free Radical Scavengers; Humans; Immunocompetence; Liver Failure; Multiple Organ Failure; Plasmapheresis; Renal Insufficiency; Rhabdomyolysis; Sepsis; Shock; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Whole Genome Sequencing

2021
Modulation of the Redox Expression and Inflammation Response in the Critically Ill Polytrauma Patient with Thoracic Injury. Statistical Correlations between Antioxidant Therapy.
    Clinical laboratory, 2016, Sep-01, Volume: 62, Issue:9

    Topics: Abbreviated Injury Scale; Acetylcysteine; Adult; Aged; Antioxidants; Ascorbic Acid; Critical Illness; Female; Humans; Incidence; Inflammation; Injury Severity Score; Length of Stay; Male; Middle Aged; Multiple Organ Failure; Multiple Trauma; Oxidation-Reduction; Oxidative Stress; Respiration, Artificial; Retrospective Studies; Sepsis; Thiamine; Thoracic Injuries

2016
Effects of reactive oxygen species scavenger on the protective action of 100% oxygen treatment against sterile inflammation in mice.
    Shock (Augusta, Ga.), 2010, Volume: 33, Issue:6

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Cytokines; Free Radical Scavengers; Heart; Inflammation; Kidney; Liver; Lung; Male; Mice; Multiple Organ Failure; Myocardium; Oxygen; Reactive Oxygen Species; Sepsis; Thiourea; Zymosan

2010
Antioxidant treatment reverses organ failure in rat model of sepsis: role of antioxidant enzymes imbalance, neutrophil infiltration, and oxidative stress.
    The Journal of surgical research, 2011, May-15, Volume: 167, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Catalase; Deferoxamine; Disease Models, Animal; Kidney; Lung; Male; Multiple Organ Failure; Neutrophil Infiltration; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Sepsis; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Urea

2011
When will we learn?
    Critical care medicine, 2004, Volume: 32, Issue:4

    Topics: Acetylcysteine; Critical Care; Humans; Intercellular Adhesion Molecule-1; Interleukin-6; Interleukin-8; Multiple Organ Failure; NF-kappa B; Randomized Controlled Trials as Topic; Systemic Inflammatory Response Syndrome; Treatment Failure

2004
Post-treatment with N-acetylcysteine ameliorates endotoxin shock-induced organ damage in conscious rats.
    Life sciences, 2006, Oct-19, Volume: 79, Issue:21

    Topics: Acetylcysteine; Animals; Blood Pressure; Cytokines; Drug Administration Schedule; Free Radical Scavengers; Heart; Heart Rate; Kidney; Kidney Function Tests; Lipopolysaccharides; Liver; Liver Function Tests; Male; Multiple Organ Failure; Myocardium; Rats; Rats, Inbred WKY; Shock, Septic

2006
Death from paracetamol overdose despite appropriate treatment with N-acetylcysteine.
    Emergency medicine journal : EMJ, 2007, Volume: 24, Issue:5

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Drug Overdose; Fatal Outcome; Free Radical Scavengers; Humans; Male; Middle Aged; Multiple Organ Failure

2007
Extrapancreatic organ impairment during acute pancreatitis induced by bile-pancreatic duct obstruction. Effect of N-acetylcysteine.
    International journal of experimental pathology, 2007, Volume: 88, Issue:5

    Topics: Acetylcysteine; Acute Disease; Alanine Transaminase; Amylases; Animals; Aspartate Aminotransferases; Bilirubin; Biomarkers; Cholestasis; Creatinine; L-Lactate Dehydrogenase; Ligation; Liver; Lung; Male; Models, Animal; Multiple Organ Failure; Pancreas; Pancreatitis; Peroxidase; Rats; Rats, Wistar; Time Factors; Treatment Outcome

2007
Protective effect of N-acetylcysteine on multiple organ failure induced by zymosan in the rat.
    Critical care medicine, 1999, Volume: 27, Issue:8

    Topics: Acetylcysteine; Animals; Body Weight; Disease Models, Animal; Drug Evaluation, Preclinical; Free Radical Scavengers; Leukocyte Count; Male; Multiple Organ Failure; Nitrates; Nitric Oxide; Peritonitis; Random Allocation; Rats; Rats, Sprague-Dawley; Shock, Septic; Survival Analysis; Time Factors; Zymosan

1999
Prevention by somatostatine and N-acetylcisteine of multiorgan failure mediated by oxidative stress after intestinal ischemia.
    Transplantation proceedings, 1999, Volume: 31, Issue:6

    Topics: Acetylcysteine; Adenosine Triphosphate; Allopurinol; Animals; Glutathione; Heart; Intestine, Small; Ischemia; Liver; Lung; Malondialdehyde; Mesenteric Arteries; Multiple Organ Failure; Myocardium; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Somatostatin

1999