acetylcysteine and Lung Diseases

acetylcysteine has been researched along with Lung Diseases in 93 studies

Research

Studies (93)

Timeframe	Studies, this research(%)	All Research%
pre-1990	37 (39.78)	18.7374
1990's	20 (21.51)	18.2507
2000's	18 (19.35)	29.6817
2010's	17 (18.28)	24.3611
2020's	1 (1.08)	2.80

Authors

Authors	Studies
Adir, Y; Alyan, M; Arber Raviv, S; Dor, E; Egorov, E; Farkash, S; Flikshtain, OD; Gal, Y; Harush, MY; Kaneti, G; Korach-Rechtman, H; Koren, L; Mekies, LN; Nudelman, I; Pieters, C; Saadya, A; Schroeder, A; Shainsky, J; Shklover, J; Zano, A	1
Abid, S; Adnot, S; Attwe, A; Beaulieu, D; Bernard, D; Born, E; Bourachot, B; Breau, M; Collin, G; Czibik, G; Flaman, JM; Houssaini, A; Lipskaia, L; Marcos, E; Mechta-Grigoriou, F; Palazzo, A; Tran Van Nhieu, J	1
Button, BM; Holland, AE; Le Maitre, C; Romero, L; Steward, R; Tarrant, BJ; Thompson, BR	1
Devereaux, A; Liang, NC	1
Ghanei, M; Hashjin, MM; Panahi, Y; Rezaee, R; Sahebkar, A	1
Chen, C; Hei, Z; Li, X; Liu, D; Wei, X; Yao, W; Zhang, Z	1
Fairhall, S; Jenner, J; Jugg, B; Mann, T; Perrott, R; Rutter, S; Salguero, J; Sciuto, AM; Shute, J; Smith, A	1
Nash, EF; Ratjen, F; Stephenson, A; Tam, J; Tullis, E	1
Akca, B; Battaloglu, B; Colak, MC; Disli, OM; Erdil, F; Erdil, N; Eroglu, T; Yetkin, O	1
Güler, G; Ozgur, E; Seyhan, N; Türközer, Z	1
Nash, EF; Ratjen, F; Stephenson, A; Tullis, E	1
Carlson, GP; Mahlapuu, R; Meszka-Jordan, A; Soomets, U	1
Breysse, PN; Chiang, ET; Chillrud, SN; Garcia, JG; Geyh, AS; Lang, GD; Moreno-Vinasco, L; Natarajan, V; Pendyala, S; Samet, JM; Wang, T	1
Celik, Y; Cigdem, MK; Kizil, G; Kizil, M; Nergiz, Y; Onen, A	1
Baas, P; Beijnen, JH; Keizer, RJ	1
Bracher, A; Doran, SF; Leustik, M; Matalon, S; Postlethwait, EM; Squadrito, GL; Yadav, AK	1
Day, BJ; Gould, NS	1
Johnson, DC	1
Gillissen, A	1
Chu, HW; Kosmider, B; Mason, RJ; Messier, EM	1
Guo, XC; Jiang, JF; Liu, HQ; Shen, C; Wang, Q; Wu, MJ; Xu, ZY; Zhou, WG; Zhu, H	1
Avlan, D; Cinel, I; Cinel, L; Dikmengil, M; Koksel, O; Okcu, H; Oral, U; Ozdulger, A; Unlu, A	1
Chatterjee, D; Das, SK; Mukherjee, S; Smith, MG	1
SUDDARTH, SB	1
REAS, HW	2
JACOBS, LW; MEDLER, EM; SARETT, HP; SHEFFNER, AL	1
WEBB, WR	1
DEGERLI, IU; WEBB, WR	1
Li, HZ; Li, SQ; Qi, HW; Wu, CG; Zhang, J	1
Boulanger, P; Guerin, JC; Lebas, FX; Leophonte, P; Liard, F; Terrioux, P	1
Aitio, ML	1
Hosogi, S; Iwasaki, Y; Kono, K; Kuwahara, H; Marunaka, Y; Nagata, K; Ohsugi, S; Yamada, T; Yuba, T	1
Chen, HI; Chuang, IC; Kao, SJ; Liu, DD	1
Doctor, BP; Gordon, RK; Katos, AM; Moran, TS; Nambiar, MP; Rezk, PE; Sciuto, AM; Steele, KE; Wajda, NA	1
Cooke, MS; Grigg, J; Panickar, JR	1
Hofer, CK; Metzger, U; Seifert, B; Zingg, U; Zollinger, A	1
Boogaard, R; de Jongste, JC; Merkus, PJ	1
Dal Pizzol, F; Pinho, RA; Rocha, LG; Silva, LA; Silveira, PC; Soares, FS; Streck, EL; Teixeira, KC; Valença, SS	1
Bartos, V; Brozmanova, M; Javorka, M; Masar, J; Plank, L; Plevkova, J; Tatar, M	1
Hsia, DY; O'Flynn, M; Rowley, WF	1
Ovchinnikov, AA; Rabicheva, MI; Vaĭsberg, LA	1
Balestra, L; Henriquet, F; Mereto, GC	1
Barbero, EA; Lucas, MC; Ludeña, MD; Sánchez-Gascón, F	1
Brien, JF; Leeder, RG; Massey, TE	1
Bernard, GR; Morris, PE	1
Avidor, I; Benjaminov, O; Hoffer, E; Merzbach, D; Shenker, L; Tabak, A; Taitelman, U; Tamir, A	1
Kelly, FJ; Langley, SC	1
Maier, KL	1
Blackwell, TR; Blackwell, TS; Christman, BW; Christman, JW; Holden, EP	1
Baum, Y; Hoffer, E; Shenker, L; Tabak, A	1
Buhl, R; Meyer, A; Vogelmeier, C	1
Ishii, Y; Kitamura, S; Yamasawa, H	1
Brand, PL; Duijvestijn, YC; Gerritsen, J	1
Meyboom-de Jong, B	1
Davreux, CJ; McGilvray, ID; Nathens, AB; Rotstein, OD; Shek, PN; Soric, I; Suntres, ZE; Watson, RW	1
Dekhuijzen, PN	1
Gillissen, A; Nowak, D	1
Domenighetti, G; Quattropani, C; Schaller, MD	1
Ben-Abraham, R; Karchevski, E; Rudick, V; Weinbroum, AA	1
Anderson, DR; Byers, SL; Vesely, KR	1
Boehm, G; Theile, H	1
Tarentini Trojani, F	1
Belik, J; Bibi, H; Oullette, M; Seifert, B	1
Bernard, GR	1
de Leval, M; Fradet, G; Helms, P; Higenbottam, TW; Scott, JP; Sharples, L; Smyth, RL; Wallwork, J; Whitehead, B	1
Jamieson, DD; Kerr, DR; Unsworth, I	1
Bebout, DE; Glennow, C; Gray, AT; Mathieu-Costello, O; Natterson, PD; Wagner, PD	1
Bernard, GR; Brigham, KL; English, DK; Lucht, WD; Serafin, WE	1
Butler, JA; Byrne, FD; Patterson, CE; Rhodes, ML	1
Balynia, NA; Ginters, JJ; Magalif, NI; Marga, OIa; Utkin, VV	1
Chiummariello, A; De Luca, L	1
Stadeler, HJ	1
Hunter, AR	1
Brooks, RC; Rao, S; Sproule, BJ; Wilson, DB	1
Ahlgren, EW	1
Günthner, W	1
Borgia, M; Porsio, A	1
Alberto, S; Brusasco, L; Colongo, PG; Frigerio, G	1
Kulkarni, TP	1
Stephan, U	1
Ciocatto, E; Marchiaro, G; Trompeo, MA	1
Fossati, C	1
Hirsch, SR; Kory, RC; Zastrow, JE	1
Lande, M	1
Carnimeo, N; Iaia, E	1
Sheffner, AL	1
Ramirez, J	1

Reviews

17 review(s) available for acetylcysteine and Lung Diseases

Article	Year
Mucoactive agents for chronic, non-cystic fibrosis lung disease: A systematic review and meta-analysis. Respirology (Carlton, Vic.), 2017, Volume: 22, Issue:6 Topics: Acetylcysteine; Administration, Inhalation; Bronchiectasis; Chronic Disease; Deoxyribonuclease I; Expectorants; Forced Expiratory Volume; Humans; Lung Diseases; Mannitol; Mesna; Mucociliary Clearance; Quality of Life; Recombinant Proteins; Saline Solution, Hypertonic; Symptom Flare Up; Vital Capacity	2017
Potential Utility of N-acetylcysteine for Treating Mustard Lung. Critical reviews in eukaryotic gene expression, 2017, Volume: 27, Issue:3 Topics: Acetylcysteine; Apoptosis; Chemical Warfare Agents; Humans; Inflammation; Lung; Lung Diseases; Mustard Gas; Oxidative Stress	2017
Nebulized and oral thiol derivatives for pulmonary disease in cystic fibrosis. The Cochrane database of systematic reviews, 2013, Jul-12, Issue:7 Topics: Acetylcysteine; Administration, Inhalation; Administration, Oral; Ambroxol; Carbocysteine; Cystic Fibrosis; Expectorants; Glutathione; Humans; Lung Diseases; Mucociliary Clearance; Nebulizers and Vaporizers; Randomized Controlled Trials as Topic; Saline Solution, Hypertonic	2013
Nebulized and oral thiol derivatives for pulmonary disease in cystic fibrosis. The Cochrane database of systematic reviews, 2009, Jan-21, Issue:1 Topics: Acetylcysteine; Administration, Inhalation; Administration, Oral; Ambroxol; Carbocysteine; Cystic Fibrosis; Expectorants; Humans; Lung Diseases; Mucociliary Clearance; Randomized Controlled Trials as Topic	2009
Mechanisms and modification of chlorine-induced lung injury in animals. Proceedings of the American Thoracic Society, 2010, Volume: 7, Issue:4 Topics: Acetylcysteine; Animals; Ascorbic Acid; Bronchoalveolar Lavage Fluid; Chlorine; Gases; Inhalation Exposure; Lung; Lung Diseases; Models, Animal; Rabbits; Rats	2010
[Oxidative stress in bronchopulmonary disease: contribution of N-acetylcysteine (NAC)]. Revue de pneumologie clinique, 2005, Volume: 61, Issue:1 Pt 1 Topics: Acetylcysteine; Glutathione; Humans; Inflammation; Lung Diseases; Oxidative Stress	2005
N-acetylcysteine -- passe-partout or much ado about nothing? British journal of clinical pharmacology, 2006, Volume: 61, Issue:1 Topics: Acetylcysteine; Anti-HIV Agents; Antioxidants; Cardiovascular Diseases; Drug Therapy, Combination; Expectorants; HIV Infections; Humans; Kidney Diseases; Liver Diseases; Lung Diseases; Neoplasms; Oxidative Stress; Reactive Oxygen Species	2006
Pharmacotherapy of impaired mucociliary clearance in non-CF pediatric lung disease. A review of the literature. Pediatric pulmonology, 2007, Volume: 42, Issue:11 Topics: Acetylcysteine; Adolescent; Child; Child, Preschool; Deoxyribonuclease I; Expectorants; Humans; Infant; Lung Diseases; Mucociliary Clearance; Physical Therapy Modalities; Randomized Controlled Trials as Topic; Saline Solution, Hypertonic	2007
Significance of glutathione in lung disease and implications for therapy. The American journal of the medical sciences, 1994, Volume: 307, Issue:2 Topics: Acetylcysteine; Animals; Cysteine; Disease Models, Animal; Glutathione; Humans; Inflammation; Lung Diseases; NF-kappa B	1994
Oxidant-protease interaction in the lung. Prospects for antioxidant therapy. Chest, 1996, Volume: 110, Issue:6 Suppl Topics: Acetylcysteine; Aerosols; Antioxidants; Glutathione; HIV Infections; Humans; Lung; Lung Diseases; Protease Inhibitors; Pulmonary Fibrosis	1996
[Acetylcysteine in children with lung disorders prescribed by one-third of family physicians: no support in the literature]. Nederlands tijdschrift voor geneeskunde, 1997, Apr-26, Volume: 141, Issue:17 Topics: Acetylcysteine; Child; Child, Preschool; Drug Prescriptions; Expectorants; Family Practice; Humans; Lung Diseases	1997
Characterization of N-acetylcysteine and ambroxol in anti-oxidant therapy. Respiratory medicine, 1998, Volume: 92, Issue:4 Topics: Acetylcysteine; Ambroxol; Animals; Expectorants; Free Radical Scavengers; Humans; Lung; Lung Diseases	1998
[Therapeutic use of N-acetylcysteine in acute lung diseases]. Revue des maladies respiratoires, 1999, Volume: 16, Issue:1 Topics: Acetylcysteine; Acute Disease; Free Radical Scavengers; Humans; Lung Diseases; Reactive Oxygen Species	1999
N-acetylcysteine in experimental and clinical acute lung injury. The American journal of medicine, 1991, Sep-30, Volume: 91, Issue:3C Topics: Acetylcysteine; Animals; Clinical Trials as Topic; Endotoxins; Free Radical Scavengers; Glutathione; Granulocytes; Humans; Lung Diseases; Models, Biological; Respiratory Distress Syndrome	1991
[Role of free radicals in respiratory pathology or the battle for an electron]. Allergie et immunologie, 1987, Volume: 19, Issue:8 Suppl Topics: Acetylcysteine; Emphysema; Free Radicals; Humans; Hydrogen Peroxide; Lung Diseases; Oxygen Consumption; Respiratory Tract Infections; Superoxides	1987
[Mucoviscidosis (review of the literature)]. Rassegna internazionale di clinica e terapia, 1968, Apr-30, Volume: 48, Issue:8 Topics: Acetylcysteine; Adult; Aerosols; Anti-Bacterial Agents; Bronchi; Bronchial Diseases; Bronchopneumonia; Cough; Cystic Fibrosis; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Lung Compliance; Lung Diseases; Middle Aged; Pancreas; Radiography; Sweating	1968
[Inhalation therapy from the modern point of view]. Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1971, Volume: 60, Issue:45 Topics: Acetylcysteine; Aerosols; Aniline Compounds; Bronchodilator Agents; Chronic Disease; Dexamethasone; Expectorants; Humans; Lung Diseases; Respiratory Function Tests; Respiratory Therapy; Respiratory Tract Diseases; Toluene	1971

Trials

6 trial(s) available for acetylcysteine and Lung Diseases

Article	Year
Bioscience reports, 2018, 10-31, Volume: 38, Issue:5 Topics: Acetylcysteine; Administration, Inhalation; Breath Tests; Exhalation; Female; Humans; Intercellular Adhesion Molecule-1; Interleukin-8; Liver Transplantation; Lung; Lung Diseases; Male; Middle Aged; Oxidative Stress; Postoperative Complications; Tumor Necrosis Factor-alpha; Uteroglobin	2018
The effects of N-acetylcysteine on pulmonary functions in patients undergoing on-pump coronary artery surgery: a double blind placebo controlled study. European review for medical and pharmacological sciences, 2016, Volume: 20, Issue:1 Topics: Acetylcysteine; Aged; Blood Gas Analysis; Cardiopulmonary Bypass; Coronary Artery Bypass; Coronary Artery Disease; Double-Blind Method; Female; Free Radical Scavengers; Humans; Lung Diseases; Male; Middle Aged; Prospective Studies; Respiratory Function Tests	2016
[Oral mucosolvin therapy of pulmonary symptoms of mucoviscidosis]. Kinderarztliche Praxis, 1979, Volume: 47, Issue:12 Topics: Acetylcysteine; Administration, Oral; Clinical Trials as Topic; Cystic Fibrosis; Humans; Infant; Lung Diseases	1979
Intratracheal N-acetylcysteine use in infants with chronic lung disease. Acta paediatrica (Oslo, Norway : 1992), 1992, Volume: 81, Issue:4 Topics: Acetylcysteine; Airway Resistance; Chronic Disease; Humans; Infant; Infant, Newborn; Infant, Premature; Instillation, Drug; Intubation, Intratracheal; Lung Compliance; Lung Diseases; Lung Volume Measurements; Prospective Studies; Pulmonary Gas Exchange; Respiration, Artificial	1992
N-acetylcysteine in experimental and clinical acute lung injury. The American journal of medicine, 1991, Sep-30, Volume: 91, Issue:3C Topics: Acetylcysteine; Animals; Clinical Trials as Topic; Endotoxins; Free Radical Scavengers; Glutathione; Granulocytes; Humans; Lung Diseases; Models, Biological; Respiratory Distress Syndrome	1991
[Studies of the clinical and respiratory functional effects of a mucolytic-antibiotic preparation in chronic bronchopulmonary diseases. Controlled double-blind single code studies]. Minerva medica, 1968, Jul-04, Volume: 59, Issue:53 Topics: Acetylcysteine; Adult; Aged; Anti-Bacterial Agents; Asthma; Bronchial Diseases; Bronchiectasis; Bronchitis; Chronic Disease; Female; Humans; Lung Abscess; Lung Diseases; Male; Middle Aged; Pulmonary Emphysema; Respiration; Respiratory Insufficiency	1968

Other Studies

71 other study(ies) available for acetylcysteine and Lung Diseases

Article	Year
Lung targeted liposomes for treating ARDS. Journal of controlled release : official journal of the Controlled Release Society, 2022, Volume: 346 Topics: Acetylcysteine; Animals; COVID-19; Humans; Inflammation; Lipopolysaccharides; Liposomes; Lung; Lung Diseases; Mice; Mice, Inbred C57BL; Nanoparticles; Respiratory Distress Syndrome; Tumor Necrosis Factor-alpha	2022
The antioxidant N-acetylcysteine protects from lung emphysema but induces lung adenocarcinoma in mice. JCI insight, 2019, 10-03, Volume: 4, Issue:19 Topics: Acetylcysteine; Adenocarcinoma of Lung; Animals; Antioxidants; Disease Models, Animal; Female; Humans; Lung; Lung Diseases; Lung Neoplasms; Male; Mice; Mice, Knockout; Oxidative Stress; Proto-Oncogene Proteins c-jun; Pulmonary Emphysema; Reactive Oxygen Species	2019
Integrative Medicine (Complementary and Alternative Medicine) for the Lungs. American journal of respiratory and critical care medicine, 2017, 06-01, Volume: 195, Issue:11 Topics: Acetylcysteine; Acupressure; Acupuncture Therapy; Antioxidants; Breathing Exercises; Complementary Therapies; Dietary Supplements; Humans; Integrative Medicine; Lung Diseases; Meditation; Mind-Body Therapies; Mindfulness; Probiotics; Transcutaneous Electric Nerve Stimulation; Vitamin D; Vitamins; Yoga	2017
N-acetyl-L-cysteine protects against inhaled sulfur mustard poisoning in the large swine. Clinical toxicology (Philadelphia, Pa.), 2013, Volume: 51, Issue:4 Topics: Acetylcysteine; Administration, Inhalation; Aerosols; Animals; Antidotes; Antioxidants; Bronchoalveolar Lavage Fluid; Chemical Warfare Agents; Disease Models, Animal; Expectorants; Female; Gas Poisoning; Lung; Lung Diseases; Mustard Gas; Neutrophil Infiltration; Random Allocation; Respiratory Insufficiency; Survival Analysis; Sus scrofa	2013
Antioxidants alleviate electric field-induced effects on lung tissue based on assays of heme oxygenase-1, protein carbonyl content, malondialdehyde, nitric oxide, and hydroxyproline. The Science of the total environment, 2009, Feb-01, Volume: 407, Issue:4 Topics: Acetylcysteine; Animals; Antioxidants; Biodiversity; Catechin; Electromagnetic Fields; Guinea Pigs; Heme Oxygenase-1; Hydroxyproline; Lung Diseases; Male; Malondialdehyde; Nitric Oxide; Protein Carbonylation; Random Allocation	2009
Oxidative stress due to (R)-styrene oxide exposure and the role of antioxidants in non-Swiss albino (NSA) mice. Journal of toxicology and environmental health. Part A, 2009, Volume: 72, Issue:10 Topics: Acetylcysteine; Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Cell Count; Chemical and Drug Induced Liver Injury; Epoxy Compounds; Glutathione; L-Iditol 2-Dehydrogenase; L-Lactate Dehydrogenase; Lung Diseases; Male; Mice; Oxidative Stress; Quinolines; Reactive Oxygen Species; Stereoisomerism; Trans-Activators	2009
Particulate matter disrupts human lung endothelial barrier integrity via ROS- and p38 MAPK-dependent pathways. American journal of respiratory cell and molecular biology, 2010, Volume: 42, Issue:4 Topics: Acetylcysteine; Air Pollutants; Antioxidants; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Humans; Imidazoles; Lung; Lung Diseases; Molecular Chaperones; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Particulate Matter; Phosphorylation; Pyridines; Reactive Oxygen Species	2010
Is there a role for antioxidants in prevention of pulmonary hypoplasia in nitrofen-induced rat model of congenital diaphragmatic hernia? Pediatric surgery international, 2010, Volume: 26, Issue:4 Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Disease Models, Animal; Drug Synergism; Female; Fetus; Free Radical Scavengers; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lipid Peroxidation; Lung; Lung Diseases; Male; Maternal-Fetal Exchange; Pesticides; Phenyl Ethers; Pregnancy; Proteins; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Vitamin E	2010
'Flooding' of the lungs and severe dyspnea in a patient with bronchoalveolar carcinoma. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2011, Volume: 17, Issue:3 Topics: Acetylcysteine; Adenocarcinoma, Bronchiolo-Alveolar; Administration, Inhalation; Administration, Oral; Dyspnea; Expectorants; Female; Humans; Hyperhomocysteinemia; Lung; Lung Diseases; Lung Neoplasms; Middle Aged; Nebulizers and Vaporizers; Risk Factors; Severity of Illness Index; Sputum	2011
Targeting maladaptive glutathione responses in lung disease. Biochemical pharmacology, 2011, Jan-15, Volume: 81, Issue:2 Topics: Acetylcysteine; Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Glutathione; Humans; Lung; Lung Diseases; Oxidation-Reduction	2011
Airway mucus function and dysfunction. The New England journal of medicine, 2011, 03-10, Volume: 364, Issue:10 Topics: Acetylcysteine; Humans; Insufflation; Lung Diseases; Mucus; Respiratory Physiological Phenomena; Tracheostomy	2011
[Anti-inflammatory efficacy of N-acetylcysteine and therapeutic usefulness]. Pneumologie (Stuttgart, Germany), 2011, Volume: 65, Issue:9 Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antioxidants; Arthritis; Bronchitis; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Expectorants; Free Radical Scavengers; Humans; Lung Diseases; Lung Diseases, Interstitial; Pulmonary Disease, Chronic Obstructive	2011
Human alveolar epithelial cell injury induced by cigarette smoke. PloS one, 2011, Volume: 6, Issue:12 Topics: Acetylcysteine; Active Transport, Cell Nucleus; Apoptosis; Benzimidazoles; Chromans; Epithelial Cells; Humans; In Situ Nick-End Labeling; Lung Diseases; Microscopy, Fluorescence; Necrosis; NF-E2-Related Factor 2; Oxidative Stress; Phenotype; Propidium; Pulmonary Alveoli; Smoking	2011
N-acetylcysteine-pretreated human embryonic mesenchymal stem cell administration protects against bleomycin-induced lung injury. The American journal of the medical sciences, 2013, Volume: 346, Issue:2 Topics: Acetylcysteine; Animals; Antibiotics, Antineoplastic; Antioxidants; Bleomycin; Cell Survival; Embryonic Stem Cells; Humans; Lung Diseases; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Nude; Reactive Oxygen Species	2013
The protective effect of N-acetylcysteine on apoptotic lung injury in cecal ligation and puncture-induced sepsis model. Shock (Augusta, Ga.), 2003, Volume: 19, Issue:4 Topics: Acetylcysteine; Animals; Apoptosis; Cecum; Disease Models, Animal; Intestinal Perforation; Ligation; Lipid Peroxidation; Lung; Lung Diseases; Male; Malondialdehyde; Nitrates; Nitrites; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Resuscitation; Systemic Inflammatory Response Syndrome	2003
Prophylactic protection by N-acetylcysteine against the pulmonary injury induced by 2-chloroethyl ethyl sulfide, a mustard analogue. Journal of biochemical and molecular toxicology, 2003, Volume: 17, Issue:3 Topics: Acetylcysteine; Animals; Caspases; Ceramides; Electrophoretic Mobility Shift Assay; Free Radical Scavengers; Free Radicals; Guinea Pigs; Lung; Lung Diseases; Male; Mustard Gas; NF-kappa B; Sphingomyelin Phosphodiesterase; Superoxide Dismutase; Tumor Necrosis Factor-alpha	2003
Acetylcysteine, a new and effective mucolytic agent. Bulletin - Geisinger Medical Center, 1963, Volume: 15 Topics: Acetylcysteine; Bronchi; Cysteine; Cystic Fibrosis; Expectorants; Humans; Lung Diseases	1963
THE USE OF N-ACETYLCYSTEINE IN THE TREATMENT OF CYSTIC FIBROSIS. Southern medical journal, 1963, Volume: 56 Topics: Acetylcysteine; Adolescent; Child; Cysteine; Cystic Fibrosis; Expectorants; Humans; Lung Diseases; Respiration; Respiratory Therapy	1963
THE IN VITRO REDUCTION IN VISCOSITY OF HUMAN TRACHEOBRONCHIAL SECRETIONS BY ACETYLCYSTEINE. The American review of respiratory disease, 1964, Volume: 90 Topics: Acetates; Acetylcysteine; Bronchitis; Chemistry Techniques, Analytical; Cysteine; Expectorants; Humans; In Vitro Techniques; Lung Diseases; Pharmacology; Pulmonary Emphysema; Ribonucleases; Sputum; Viscosity	1964
NEW MUCOLYTIC AGENTS FOR SPUTUM LIQUEFACTION. Postgraduate medicine, 1964, Volume: 36 Topics: Acetylcysteine; Asthma; Bronchial Diseases; Cysteine; Cystic Fibrosis; Expectorants; Fibrin; Humans; Lung Diseases; Mucus; Sputum; Toxicology	1964
THE USE OF N-ACETYLCYSTEINE IN THE TREATMENT OF CYSTIC FIBROSIS. The Journal of pediatrics, 1964, Volume: 65 Topics: Acetylcysteine; Adolescent; Child; Cysteine; Cystic Fibrosis; Humans; Infant; Klebsiella; Lung Diseases; Pneumonia; Proteus Infections; Pseudomonas Infections; Pulmonary Emphysema; Radiography, Thoracic; Respiratory Function Tests; Respiratory Therapy; Spirometry; Staphylococcal Infections	1964
[EFFECTIVENESS OF A NEW MUCOLYTIC AGENT, ACETYLCYSTEINE, IN POSTOPERATIVE PULMONARY COMPLICATIONS]. Turk Tip Cemiyeti mecmuasi, 1965, Volume: 31 Topics: Acetylcysteine; Drug Therapy; Expectorants; Humans; Lung Diseases; Postoperative Complications; Postoperative Period	1965
[NF-kappaB expression in lung tissue of acute lung injury rat model and the influence by antioxidant N-acetylcysteine]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2004, Volume: 20, Issue:6 Topics: Acetylcysteine; Animals; Epithelial Cells; Lipopolysaccharides; Lung; Lung Diseases; Male; NF-kappa B; Rats; Rats, Sprague-Dawley	2004
Overexpression of manganese superoxide dismutase by N-acetylcysteine in hyperoxic lung injury. Respiratory medicine, 2007, Volume: 101, Issue:4 Topics: Acetylcysteine; Administration, Inhalation; Aerosols; Animals; Blotting, Western; Bronchoalveolar Lavage Fluid; Cell Count; Free Radical Scavengers; Glutathione; Hyperoxia; Lipid Peroxidation; Lung; Lung Diseases; Male; Mice; Mice, Inbred C57BL; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superoxide Dismutase	2007
N-acetylcysteine attenuates the acute lung injury caused by phorbol myristate acetate in isolated rat lungs. Pulmonary pharmacology & therapeutics, 2007, Volume: 20, Issue:6 Topics: Acetylcysteine; Acute Disease; Animals; Blood Pressure; Body Weight; Bronchoalveolar Lavage Fluid; Capillary Permeability; Expectorants; Free Radical Scavengers; In Vitro Techniques; Inflammation Mediators; Lung; Lung Diseases; Male; Nitric Oxide; Organ Size; Pulmonary Artery; Pulmonary Edema; Random Allocation; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate	2007
Medical countermeasure against respiratory toxicity and acute lung injury following inhalation exposure to chemical warfare nerve agent VX. Toxicology and applied pharmacology, 2007, Volume: 219, Issue:2-3 Topics: Acetylcysteine; Acute Disease; Animals; Atropine Derivatives; Body Weight; Bronchoalveolar Lavage Fluid; Chemical Warfare Agents; Guinea Pigs; Inhalation Exposure; Lung Diseases; Male; Organ Size; Organothiophosphorus Compounds; Proteins; Pulmonary Surfactants; Respiratory Mucosa	2007
Case 3-2007: a boy with respiratory insufficiency. The New England journal of medicine, 2007, May-31, Volume: 356, Issue:22 Topics: Acetylcysteine; Child; Female; Free Radical Scavengers; Glutathione; Hemosiderosis; Humans; Lung Diseases; Male; Oxidative Stress; Respiratory Insufficiency	2007
High dose N-acetylcysteine to prevent pulmonary complications in partial or total transthoracic esophagectomy: results of a prospective observational study. Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2007, Volume: 20, Issue:5 Topics: Acetylcysteine; Dose-Response Relationship, Drug; Esophageal Neoplasms; Esophagectomy; Female; Follow-Up Studies; Free Radical Scavengers; Humans; Length of Stay; Lung Diseases; Male; Middle Aged; Oxygen; Postoperative Period; Prospective Studies; Retrospective Studies; Treatment Outcome	2007
Attenuation of bleomycin-induced lung injury and oxidative stress by N-acetylcysteine plus deferoxamine. Pulmonary pharmacology & therapeutics, 2008, Volume: 21, Issue:2 Topics: Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Bleomycin; Catalase; Deferoxamine; Drug Therapy, Combination; Fibrosis; Iron Chelating Agents; L-Lactate Dehydrogenase; Lipid Peroxidation; Lung; Lung Diseases; Male; Mice; Mice, Inbred Strains; Oxidative Stress; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances	2008
Oral N-acetylcysteine reverses hyperoxia-related cough suppression in guinea pigs. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2007, Volume: 58 Suppl 5, Issue:Pt 1 Topics: Acetylcysteine; Administration, Oral; Animals; Antioxidants; Citric Acid; Cough; Disease Models, Animal; Guinea Pigs; Hyperoxia; Lung; Lung Diseases; Male; Oxidative Stress; Physical Stimulation; Reflex	2007
Cystic fibrosis of the pancreas. Advances in cardiopulmonary diseases, 1966, Volume: 3 Topics: Acetylcysteine; Anti-Bacterial Agents; Bronchi; Bronchial Diseases; Child; Cystic Fibrosis; Digestive System; Drainage; Fecal Impaction; Humans; Hyperglycemia; Intestinal Obstruction; Liver Cirrhosis; Lung; Lung Diseases; Meconium; Mucus; Pneumatosis Cystoides Intestinalis; Respiratory Function Tests; Respiratory Insufficiency; Respiratory Therapy; Respiratory Tract Diseases; Salivary Glands; Sweat	1966
[Comparative effectiveness of various methods of bronchoscopic sanation in chronic nonspecific lung diseases]. Terapevticheskii arkhiv, 1980, Volume: 52, Issue:3 Topics: Acetylcysteine; Adolescent; Adult; Aged; Bronchoscopy; Evaluation Studies as Topic; Expectorants; Furagin; Humans; Lung Diseases; Mesna; Middle Aged; Sodium Chloride; Therapeutic Irrigation	1980
Alveolar surfactant in lungs of operated patients after acetylcysteine treatment. European journal of respiratory diseases. Supplement, 1980, Volume: 111 Topics: Acetylcysteine; Humans; Lung Diseases; Pulmonary Alveoli; Pulmonary Surfactants	1980
Effects of N-acetylcysteine on hyperoxic lung in the rat. Respiratory medicine, 1995, Volume: 89, Issue:4 Topics: Acetylcysteine; Animals; Hyperoxia; Lung Diseases; Rats; Rats, Wistar	1995
Investigation of the role of oxidative stress in amiodarone-induced pulmonary toxicity in the hamster. Canadian journal of physiology and pharmacology, 1994, Volume: 72, Issue:6 Topics: Acetylcysteine; Allyl Compounds; Amiodarone; Animals; Antioxidants; Butylated Hydroxyanisole; Cricetinae; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Lung; Lung Diseases; Male; Mesocricetus; Oxidative Stress; Pulmonary Fibrosis; Sulfides; Superoxide Dismutase	1994
N-acetylcysteine delays the infiltration of inflammatory cells into the lungs of paraquat-intoxicated rats. Toxicology and applied pharmacology, 1993, Volume: 120, Issue:1 Topics: Acetylcysteine; Animals; Bronchoalveolar Lavage Fluid; Chemotactic Factors; Chemotaxis, Leukocyte; Inflammation; Liver; Lung Diseases; Male; Neutrophils; Paraquat; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Superoxides	1993
N-acetylcysteine ameliorates hyperoxic lung injury in the preterm guinea pig. Biochemical pharmacology, 1993, Feb-24, Volume: 45, Issue:4 Topics: Acetylcysteine; Animals; Bronchoalveolar Lavage Fluid; Catalase; Disease Models, Animal; Female; Glutathione; Glutathione Peroxidase; Guinea Pigs; Humans; Infant, Newborn; Infant, Premature, Diseases; Lung; Lung Diseases; Oxygen; Proteins; Ventilators, Mechanical	1993
How the lung deals with oxidants. The European respiratory journal, 1993, Volume: 6, Issue:3 Topics: Acetylcysteine; Alveolitis, Extrinsic Allergic; Animals; Free Radical Scavengers; Humans; Lung; Lung Diseases; Nitrogen Dioxide; Ozone; Reactive Oxygen Species; Respiratory Burst; Smoking	1993
In vivo antioxidant treatment suppresses nuclear factor-kappa B activation and neutrophilic lung inflammation. Journal of immunology (Baltimore, Md. : 1950), 1996, Aug-15, Volume: 157, Issue:4 Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Base Sequence; Chemokines, CXC; Chemotactic Factors; Chemotaxis, Leukocyte; Dinoprost; Disease Models, Animal; Drug Evaluation, Preclinical; Endotoxins; F2-Isoprostanes; Gene Expression Regulation; Glutathione; Growth Substances; Inflammation; Intercellular Signaling Peptides and Proteins; Leukocyte Count; Lung; Lung Diseases; Male; Molecular Sequence Data; Neutrophils; NF-kappa B; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; RNA, Messenger; Sepsis	1996
Paraquat-induced formation of leukotriene B4 in rat lungs: modulation by N-acetylcysteine. Free radical biology & medicine, 1997, Volume: 22, Issue:3 Topics: Acetylcysteine; Animals; Arachidonic Acid; Bronchoalveolar Lavage Fluid; Female; Leukotriene B4; Lung; Lung Diseases; Macrophages, Alveolar; Neutrophils; Paraquat; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley	1997
[Role of oxidants in adhesion molecule expression and cytokine production]. Nihon Kyobu Shikkan Gakkai zasshi, 1996, Volume: 34 Suppl Topics: Acetylcysteine; Animals; Antioxidants; Bronchi; Cells, Cultured; Humans; Intercellular Adhesion Molecule-1; Interleukin-8; Lung Diseases; Rats; Reactive Oxygen Species; Tumor Necrosis Factor-alpha	1996
[Acetylcysteine prescribed by one third of family physicians for lung diseases in children; no proof in the literature]. Nederlands tijdschrift voor geneeskunde, 1997, Jun-14, Volume: 141, Issue:24 Topics: Acetylcysteine; Child; Drug Prescriptions; Expectorants; Family Practice; Humans; Lung Diseases; Practice Patterns, Physicians'	1997
N-acetyl cysteine attenuates acute lung injury in the rat. Shock (Augusta, Ga.), 1997, Volume: 8, Issue:6 Topics: Acetylcysteine; Acute Disease; Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Capillary Permeability; CD11 Antigens; Cell Count; Disease Models, Animal; Dose-Response Relationship, Drug; Endotoxins; Glutathione; Hemorrhage; Lipid Peroxidation; Lipopolysaccharides; Liver; Lung; Lung Diseases; Lung Injury; Male; Neutrophil Activation; Neutrophils; Peroxidase; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha	1997
[Acetylcysteine in children with lung disorders prescribed by one third of family physicians; no support in the literature]. Nederlands tijdschrift voor geneeskunde, 1997, Aug-02, Volume: 141, Issue:31 Topics: Acetylcysteine; Child; Expectorants; Humans; Lung Diseases	1997
N-acetyl-L-cysteine for preventing lung reperfusion injury after liver ischemia-reperfusion: a possible dual protective mechanism in a dose-response study. Transplantation, 2000, Mar-15, Volume: 69, Issue:5 Topics: Acetylcysteine; Animals; Dose-Response Relationship, Drug; Free Radical Scavengers; Glutathione; Ischemia; Liver; Liver Circulation; Lung; Lung Diseases; Male; Perfusion; Pulmonary Circulation; Rats; Rats, Wistar; Reperfusion Injury; Respiration; Xanthine Oxidase	2000
Treatment of sulfur mustard (HD)-induced lung injury. Journal of applied toxicology : JAT, 2000, Volume: 20 Suppl 1 Topics: Acetylcysteine; Animals; Bronchoalveolar Lavage; Dermatologic Agents; Free Radical Scavengers; gamma-Glutamyltransferase; Lung; Lung Diseases; Male; Mustard Gas; Neutrophils; Niacinamide; Rats	2000
[Pulmonary aging. Meeting at the Istituto Superiore di Sanità in Rome]. La Clinica terapeutica, 1992, Volume: 140, Issue:5 Topics: Acetylcysteine; Adult; Aging; Bronchitis; Chronic Disease; Clinical Trials as Topic; Humans; Lung; Lung Diseases; Multicenter Studies as Topic; Smoking	1992
The use of heart-lung transplantation in management of terminal respiratory complications of cystic fibrosis. Transplantation proceedings, 1990, Volume: 22, Issue:4 Topics: Acetylcysteine; Adult; Constipation; Cystic Fibrosis; Follow-Up Studies; Heart-Lung Transplantation; Humans; Lung Diseases; Prognosis	1990
Interaction of N-acetylcysteine and bleomycin on hyperbaric oxygen-induced lung damage in mice. Lung, 1987, Volume: 165, Issue:4 Topics: Acetylcysteine; Animals; Bleomycin; Hyperbaric Oxygenation; Lung; Lung Diseases; Male; Mice; Mice, Inbred BALB C; Oxygen	1987
Protection against pulmonary O2 toxicity by N-acetylcysteine. The European respiratory journal, 1989, Volume: 2, Issue:2 Topics: Acetylcysteine; Administration, Oral; Animals; Antioxidants; Dogs; Free Radicals; Glutathione; Lung Diseases; Oxygen; Respiratory Distress Syndrome; Respiratory Function Tests	1989
Prevention of release of granulocyte aggregants into sheep lung lymph following endotoxemia by N-acetylcysteine. The American journal of the medical sciences, 1987, Volume: 294, Issue:3 Topics: Acetylcysteine; Animals; Cell Adhesion; Cell Aggregation; Endotoxins; Granulocytes; Leukotriene B4; Lung Diseases; Lymph; Neutrophils; Sheep	1987
Tobacco smoke: respiratory tract defense mechanisms and therapeutic implications. An international symposium held in Lugano, CH, April 13-14, 1984. European journal of respiratory diseases. Supplement, 1985, Volume: 139 Topics: Acetylcysteine; Humans; Lung; Lung Diseases; Smoke; Smoking	1985
Oxidant lung injury: intervention with sulfhydryl reagents. Lung, 1985, Volume: 163, Issue:1 Topics: Acetylcysteine; Animals; Cysteamine; Humans; Lung Diseases; Mice; Oxygen; Paraquat; Rats; Rats, Inbred Strains; Sulfhydryl Compounds	1985
[Evaluation of the use of N-acetylcysteine in chronic suppurative diseases of the lungs]. Klinicheskaia meditsina, 1972, Volume: 50, Issue:12 Topics: Acetylcysteine; Adolescent; Bronchial Diseases; Bronchoscopy; Chronic Disease; Humans; Lung Diseases; Male; Middle Aged; Respiratory Therapy; Suppuration; Therapeutic Irrigation	1972
Treatment by artificial ventilation of the lungs. International anesthesiology clinics, 1967,Spring, Volume: 5, Issue:1 Topics: Acetylcysteine; Asthma; Barbiturates; Glutethimide; Humans; Humidity; Infections; Intensive Care Units; Intubation, Intratracheal; Lung Diseases; Myasthenia Gravis; Neurologic Manifestations; Nursing Care; Parenteral Nutrition; Perfusion; Porphyrias; Pulmonary Emphysema; Respiration, Artificial; Seizures; Thoracic Injuries; Tracheal Stenosis; Tracheotomy	1967
Acute effects of nebulization of N-acetylcysteine on pulmonary mechanics and gas exchange. The American review of respiratory disease, 1970, Volume: 102, Issue:1 Topics: Acetylcysteine; Aerosols; Blood Gas Analysis; Bronchial Spasm; Female; Humans; Hypercapnia; Hypoxia; Lung Compliance; Lung Diseases; Male; Respiration; Spirometry; Ventilation-Perfusion Ratio	1970
Acetylcysteine--Respaire and Mucomyst. The Medical letter on drugs and therapeutics, 1970, Mar-20, Volume: 12, Issue:6 Topics: Acetylcysteine; Cystic Fibrosis; Humans; Lung Diseases	1970
Aerosol drug therapy. International anesthesiology clinics, 1970,Fall, Volume: 8, Issue:3 Topics: Acetylcysteine; Aerosols; Anti-Bacterial Agents; Catecholamines; Deoxyribonucleases; Dexamethasone; Humans; Lung Diseases; Pharmaceutical Vehicles; Surface-Active Agents; Theophylline	1970
[Inhalation therapy using secretolytics]. Medizinische Klinik, 1971, May-07, Volume: 66, Issue:19 Topics: Acetylcysteine; Airway Resistance; Ammonium Chloride; Blood Gas Analysis; Detergents; Health Resorts; Humans; Lung Diseases; Lung Diseases, Obstructive; Oils, Volatile; Plethysmography, Whole Body; Respiratory Function Tests; Respiratory Therapy; Time Factors	1971
[General use of N-acetyl-L-cysteine: controled evaluation of the mucolytic activity and tolerability]. La Clinica terapeutica, 1967, Apr-15, Volume: 41, Issue:1 Topics: Acetylcysteine; Adult; Female; Humans; Lung Diseases; Male; Middle Aged; Respiratory Insufficiency	1967
Clinical experience with acetylcysteine--a mucolytic agent. Journal of the Indian Medical Association, 1968, Dec-16, Volume: 51, Issue:12 Topics: Acetylcysteine; Bronchiectasis; Humans; Lung Abscess; Lung Diseases; Postoperative Complications	1968
[Mucoviscidosis]. Der Landarzt, 1968, Dec-10, Volume: 44, Issue:34 Topics: Acetylcysteine; Aerosols; Anti-Bacterial Agents; Child; Cystic Fibrosis; Drainage; Humans; Lung Diseases; Pancreatic Extracts; Radiography; Ultrasonic Therapy	1968
[Preliminary experience with parenteral N-acetyl-L-cysteine in resuscitation]. Minerva anestesiologica, 1968, Volume: 34, Issue:5 Topics: Acetylcysteine; Adult; Aged; Coma; Female; Humans; Infusions, Parenteral; Injections, Intramuscular; Lung Diseases; Male; Middle Aged; Pneumothorax; Poisoning; Respiratory Insufficiency; Resuscitation	1968
[A new mucolytic alone or associated with an antibiotic in the treatment of bronchial-pleural-pulmonary diseases]. La Clinica terapeutica, 1968, Feb-15, Volume: 44, Issue:3 Topics: Acetates; Acetylcysteine; Aerosols; Bronchial Diseases; Drug Synergism; Empyema; Humans; Lung Diseases; Pleural Diseases	1968
Sputum liquefying agents: a comparative in vitro evaluation. The Journal of laboratory and clinical medicine, 1969, Volume: 74, Issue:2 Topics: Acetylcysteine; Bicarbonates; Humans; Lung Diseases; Mercaptoethanol; Methods; Potassium Iodide; Sodium Chloride; Sputum; Sulfhydryl Compounds; Sulfonic Acids; Urea; Viscosity	1969
[A mucolytic agent: actylcysteine in the prevention and treatment of postoperative pulmonary complications]. La Presse medicale, 1965, Oct-23, Volume: 73, Issue:44 Topics: Acetylcysteine; Humans; Lung Diseases; Postoperative Complications	1965
[Experiences on aerosol treatment of bronchopulmonary diseases with tetracycline-1-methylene-lysine combined with acetylcysteine]. Gazzetta medica italiana, 1965, Volume: 124, Issue:8 Topics: Acetylcysteine; Adolescent; Adult; Aged; Bronchial Diseases; Female; Heart Diseases; Humans; Lung Diseases; Lymecycline; Male; Middle Aged; Tetracycline	1965
Pharmacologic agents. Aspen Emphysema Conference, 1965, Volume: 8 Topics: Acetylcysteine; Acidosis, Respiratory; Anticoagulants; Bicarbonates; Bronchodilator Agents; Chymotrypsin; Ephedrine; Expectorants; Glucocorticoids; Guaiacol; Humans; Iodine Isotopes; Isoproterenol; Lung Diseases; Lung Diseases, Obstructive; Potassium Iodide; Sodium; Thyroid Gland; Tromethamine; Trypsin	1965
Airbron. Drug and therapeutics bulletin, 1966, Jan-07, Volume: 4, Issue:1 Topics: Acetylcysteine; Aerosols; Bronchial Diseases; Humans; Lung Diseases	1966
The mucolytic action of acetylcysteine. Tuberculology and thoracic diseases, 1966, Volume: 23, Issue:2 Topics: Acetylcysteine; Humans; In Vitro Techniques; Lung Diseases; Sputum	1966
Bronchopulmonary lavage. New techniques and observations. Diseases of the chest, 1966, Volume: 50, Issue:6 Topics: Acetylcysteine; Amyloidosis; Asthma; Bronchitis; Bronchospirometry; Heparin; Humans; Intubation, Intratracheal; Lung Diseases; Pulmonary Alveolar Proteinosis; Solutions; Therapeutic Irrigation	1966