acetylcysteine and Liver Steatosis

acetylcysteine has been researched along with Liver Steatosis in 33 studies

Research

Studies (33)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (6.06)	18.2507
2000's	14 (42.42)	29.6817
2010's	13 (39.39)	24.3611
2020's	4 (12.12)	2.80

Authors

Authors	Studies
Albanese, C; Cui, W; Cui, Y; Duttargi, A; Fishbein, TM; Frank, BS; He, B; Kallakury, B; Kang, J; Khan, K; Kroemer, A; Kwon, D; Lee, Y; Levi, M; Li, HH; Libby, A; Liggett, JR; Loh, K; Nguyen, S; Oza, K; Patil, D; Ranjit, S; Robson, SC; Rodriguez, O	1
Ding, C; Gu, Y; Li, Z; Liu, B; Tang, W; Wang, Z; Yu, T; Zhang, C	1
Bai, H; Chang, X; Dong, W; Feng, C; Ma, Q; Wu, Z; Yang, J	1
Chen, YJ; Huang, LT; Lin, IC; Sheen, JM; Tain, YL; Tiao, MM; Tsai, CC; Wang, PW; Yu, HR	1
Ganz, T; Jung, G; Monga, SP; Nagarajan, S; Poddar, M; Popovic, B; Preziosi, ME; Singh, S; Valore, EV	1
Carrilho, FJ; Cogliati, B; de Oliveira, CP; de Oliveira, MG; de Souza, GF; Ferreira Alves, VA; Lima, FR; Mazo, DF; Pereira, IV; Rabelo, F; Stefano, JT	1
An, W; Jiang, S; Li, Y; Yu, H; Zhang, J	1
Hu, C; Huang, L; Liu, B; Pan, P; Su, X; Zhang, Y	1
Alves, VA; Carrilho, FJ; de Lima, VM; de Mello, ES; de Oliveira, CP; de Oliveira, MG; de Souza, HP; Laurindo, FR; Simplicio, FI; Soriano, FG	1
Albano, E; Badger, TM; Baumgardner, JN; Hennings, L; Ronis, MJ; Shankar, K	1
Boncompagni, E; Carlucci, F; Cillo, U; Ferrigno, A; Freitas, I; Gringeri, E; Neri, D; Rizzo, V; Tabucchi, A; Vairetti, M	1
Dhawan, A; Dziechciarz, P; Horvath, A; Socha, P; Szajewska, H; Vajro, P	1
Aktas, S; Dursun, N; Gunerhan, Y; Kadioglu, H; Koksal, N; Sehirli, AO; Uzun, MA	1
Moreno-Otero, R; Trapero-Marugán, M	1
Dhawan, A; Heaton, ND; Hughes, RD; Lehec, SC; Mieli-Vergani, G; Mitry, RR; Patel, AG; Rela, M; Sagias, FG	1
Andraus, W; Coelho, AM; D'Albuquerque, LA; Galvão, FH; Haddad, LB; Leitão, RM; Machado, MC; Oliveira, MG; Souza, GF	1
Albano, E; Apostolov, EO; Badger, TM; Basnakian, AG; Hennings, L; Petersen, DR; Ronis, MJ; Stewart, B	1
El-Agamy, DS; Said, SA	1
Hanczko, R; Landas, S; Oaks, Z; Perl, A; Telarico, T	1
Crum, A; Crum, AC; French, SW; Kim, H; Kim, HJ; Norris, KC; Rajavashisth, TB; Shen, R; Sinha-Hikim, AP; Sinha-Hikim, I; Vaziri, ND	1
Baghdadi, H; Baren, JP; Beckett, G; Burgess, KE; Filippi, C; Hayes, PC; Howie, F; Jaap, AJ; Lee, P; Lockman, KA; Pemberton, CJ; Plevris, JN; Plevris-Papaioannou, N; Pryde, A	1
Dhakal, K; Gadupudi, GS; Lai, IK; Li, M; Ludewig, G; Olivier, AK; Robertson, LW	1
Pamuk, GE; Sonsuz, A	1
Davidson, BR; Fusai, G; Glantzounis, GK; Hafez, T; Kanoria, S; Parkes, H; Quaglia, A; Seifalian, A; Sheth, H; Yang, W	1
Al-Osaimi, AM; Argo, CK; Caldwell, SH; Chang, CY	1
Abdalla, DS; Alves, VA; Carrilho, FJ; de Lima, VM; de Oliveira, CP; de Oliveira, MG; Laurindo, FR; Lopasso, FP; Simplicio, FI; Yuahasi, K	1
Alves, VA; Carrilho, FJ; Corrêa-Giannella, ML; de Lima, VM; de Mello, ES; de Oliveira, CP; de Oliveira, MG; de Sá, SV; Giannella-Neto, D; Laurindo, FR; Simplicio, FI; Stefano, JT	1
Coleman, MA; De Silva, A; Gregory, TL; Hughes, S	1
Klaikeaw, N; Kulaputana, O; Patumraj, S; Samuhasaneeto, S; Thong-Ngam, D	1
Alves, VA; Caldwell, S; Carrilho, FJ; Corrêa-Giannella, ML; de Mello, ES; de Oliveira, MG; Debbas, V; Giannella-Neto, D; Havaki, S; Laurindo, FR; Lima, VM; Marinos, E; Oliveira, CP; Sá, SV; Stefano, JT; Tiniakos, DG; Wakamatsu, A	1
Klaikeaw, N; Kulaputana, O; Samuhasaneeto, S; Thong-Ngam, D	1
Baek, Y; Barama, A; Boudjema, K; Jaeck, D; Kitamura, N; Kumada, K; Nagasaki, H; Nakano, H; Suzuki, T; Tatsuno, M; Yamaguchi, M	1
Fujiwara, Y; Kigawa, G; Kitamura, N; Kumada, K; Kuzume, M; Nagasaki, H; Nakano, H; Sasaki, J; Shimura, H; Takeuchi, S; Yamaguchi, M; Yoshida, K	1

Reviews

3 review(s) available for acetylcysteine and Liver Steatosis

Article	Year
Pharmacological interventions for nonalcoholic fatty liver disease in adults and in children: a systematic review. Journal of pediatric gastroenterology and nutrition, 2009, Volume: 48, Issue:5 Topics: Acetylcysteine; Adult; Alanine Transaminase; Aspartate Aminotransferases; Carnitine; Child; Dietary Supplements; Drug Synergism; Drug Therapy, Combination; Fatty Liver; Humans; Hypoglycemic Agents; Liver; Metformin; Pioglitazone; Probucol; Randomized Controlled Trials as Topic; Thiazolidinediones; Ursodeoxycholic Acid; Vitamin E	2009
Oxidative stress, inflammation and carcinogenesis are controlled through the pentose phosphate pathway by transaldolase. Trends in molecular medicine, 2011, Volume: 17, Issue:7 Topics: Acetylcysteine; Animals; Autoimmunity; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Fatty Liver; Glucose; Humans; Infertility, Male; Inflammation; Male; Mitochondria; Oxidative Stress; Pentose Phosphate Pathway; Sperm Motility; Transaldolase	2011
Therapy of NAFLD: antioxidants and cytoprotective agents. Journal of clinical gastroenterology, 2006, Volume: 40 Suppl 1 Topics: Acetylcysteine; Antioxidants; Betaine; Cholagogues and Choleretics; Disease Progression; Fatty Liver; Humans; Lipid Peroxidation; S-Adenosylmethionine; Ursodeoxycholic Acid; Vitamin E	2006

Trials

1 trial(s) available for acetylcysteine and Liver Steatosis

Article	Year
N-acetylcysteine in the treatment of non-alcoholic steatohepatitis. Journal of gastroenterology and hepatology, 2003, Volume: 18, Issue:10 Topics: Acetylcysteine; Fatty Liver; Female; Hepatitis; Humans; Male; Middle Aged	2003

Other Studies

29 other study(ies) available for acetylcysteine and Liver Steatosis

Article	Year
Oral N-acetylcysteine decreases IFN-γ production and ameliorates ischemia-reperfusion injury in steatotic livers. Frontiers in immunology, 2022, Volume: 13 Topics: Acetylcysteine; Animals; Cytokines; Fatty Liver; Interferon-gamma; Ligands; Mice; Mice, Inbred C57BL; Peroxisome Proliferator-Activated Receptors; Phospholipids; Reperfusion Injury; Triglycerides	2022
Hepatic ROS Mediated Macrophage Activation Is Responsible for Irinotecan Induced Liver Injury. Cells, 2022, Nov-26, Volume: 11, Issue:23 Topics: Acetylcysteine; Animals; Chemical and Drug Induced Liver Injury, Chronic; Fatty Liver; Hepatocytes; Irinotecan; Macrophage Activation; Mice	2022
Aflatoxin B1-induced early developmental hepatotoxicity in larvae zebrafish. Chemosphere, 2023, Volume: 340 Topics: Acetylcysteine; Aflatoxin B1; Animals; Chemical and Drug Induced Liver Injury; Fatty Liver; Larva; Zebrafish	2023
Long term N-acetylcysteine administration rescues liver steatosis via endoplasmic reticulum stress with unfolded protein response in mice. Lipids in health and disease, 2020, May-25, Volume: 19, Issue:1 Topics: Acetylcysteine; Activating Transcription Factor 4; Animals; Antioxidants; Apoptosis; Chaperonin 60; Diet, High-Fat; Endoplasmic Reticulum Stress; Enoyl-CoA Hydratase; Fatty Liver; Gene Expression Regulation; HSP70 Heat-Shock Proteins; Liver; Male; Mice; Mice, Inbred C57BL; Mitochondrial Proteins; Non-alcoholic Fatty Liver Disease; Unfolded Protein Response	2020
Mice lacking liver-specific β-catenin develop steatohepatitis and fibrosis after iron overload. Journal of hepatology, 2017, Volume: 67, Issue:2 Topics: Acetylcysteine; Animals; Antioxidants; beta Catenin; Disease Models, Animal; Fatty Liver; Female; Hemochromatosis; Humans; Iron Overload; Liver; Liver Cirrhosis; Male; Mice; Mice, Knockout; Oxidative Stress; Signal Transduction	2017
S-nitroso-N-acetylcysteine attenuates liver fibrosis in experimental nonalcoholic steatohepatitis. Drug design, development and therapy, 2013, Volume: 7 Topics: Acetylcysteine; Animals; Fatty Liver; Immunohistochemistry; Liver Cirrhosis, Experimental; Matrix Metalloproteinase 13; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Rats; Rats, Sprague-Dawley	2013
Enhanced endoplasmic reticulum SERCA activity by overexpression of hepatic stimulator substance gene prevents hepatic cells from ER stress-induced apoptosis. American journal of physiology. Cell physiology, 2014, Feb-01, Volume: 306, Issue:3 Topics: Acetylcysteine; Apoptosis; Calcium; Cell Line, Tumor; Cell Survival; Down-Regulation; eIF-2 Kinase; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Eukaryotic Initiation Factor-2; Fatty Acids, Nonesterified; Fatty Liver; Heat-Shock Proteins; Hepatocytes; Humans; Intercellular Signaling Peptides and Proteins; Liver; Non-alcoholic Fatty Liver Disease; Peptides; Reactive Oxygen Species; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Signal Transduction; Sterol Regulatory Element Binding Proteins; Transcription Factor CHOP; Transfection	2014
[Effect of chronic intermittent hypoxia on the expression of CXC chemokine ligand-10 in rat liver and the interventional effect of N-acetylcysteine]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2016, Volume: 41, Issue:8 Topics: Acetylcysteine; Animals; Chemokine CXCL10; Fatty Liver; Hypoxia; Inflammation; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley	2016
Prevention and reversion of nonalcoholic steatohepatitis in OB/OB mice by S-nitroso-N-acetylcysteine treatment. Journal of the American College of Nutrition, 2008, Volume: 27, Issue:2 Topics: Acetylcysteine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Cholesterol; Fatty Liver; Glutathione; Histocytochemistry; Male; Mice; Mice, Obese; Nitric Oxide Donors; Oxidative Stress; Thiobarbituric Acid Reactive Substances; Triglycerides	2008
N-acetylcysteine attenuates progression of liver pathology in a rat model of nonalcoholic steatohepatitis. The Journal of nutrition, 2008, Volume: 138, Issue:10 Topics: Acetylcysteine; Animals; Autoantibodies; Disease Models, Animal; Energy Intake; Fatty Liver; Glutathione; Inflammation; Liver; Liver Function Tests; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Triglycerides	2008
Subnormothermic machine perfusion protects steatotic livers against preservation injury: a potential for donor pool increase? Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2009, Volume: 15, Issue:1 Topics: Acetylcysteine; Animals; Bile; Cell Survival; Fatty Liver; Glucose; Glycogen; Liver; Male; Organ Preservation; Perfusion; Rats; Rats, Zucker; Reactive Oxygen Species; Temperature; Tissue Donors	2009
Effects of N-acetylcysteine on regeneration following partial hepatectomy in rats with nonalcoholic fatty liver disease. Surgery today, 2009, Volume: 39, Issue:7 Topics: Acetylcysteine; Animals; Antioxidants; Fatty Liver; Hepatectomy; Liver Regeneration; Male; Mitotic Index; Oxidative Stress; Rats; Rats, Wistar	2009
Hepatoprotective effects of antioxidants in chronic hepatitis C. World journal of gastroenterology, 2010, Apr-21, Volume: 16, Issue:15 Topics: Acetylcysteine; Antioxidants; Disease Progression; Fatty Liver; Fibrosis; Hepacivirus; Hepatitis C, Chronic; Humans; Liver; Nitric Oxide; Oxidative Stress; S-Adenosylmethionine; Virus Replication	2010
N-acetylcysteine improves the viability of human hepatocytes isolated from severely steatotic donor liver tissue. Cell transplantation, 2010, Volume: 19, Issue:11 Topics: Acetylcysteine; Adult; Aged; Cell Separation; Cell Survival; Fatty Liver; Female; Hepatocytes; Humans; Liver Transplantation; Male; Middle Aged; Tissue Donors	2010
S-nitroso-N-acetylcysteine ameliorates ischemia-reperfusion injury in the steatotic liver. Clinics (Sao Paulo, Brazil), 2010, Volume: 65, Issue:7 Topics: Acetylcysteine; Animals; Case-Control Studies; Disease Models, Animal; Fatty Liver; Free Radical Scavengers; Liver; Male; Oxidative Stress; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Statistics, Nonparametric; Time Factors	2010
Effects of long-term ethanol administration in a rat total enteral nutrition model of alcoholic liver disease. American journal of physiology. Gastrointestinal and liver physiology, 2011, Volume: 300, Issue:1 Topics: Acetylcysteine; Animals; Cell Proliferation; Cytochrome P-450 Enzyme System; Dietary Fats; Enteral Nutrition; Ethanol; Fatty Liver; Hedgehog Proteins; Lipid Metabolism; Liver; Liver Diseases, Alcoholic; Liver Regeneration; Male; Oxidative Stress; Rats	2011
Prevention of sodium valproate-induced hepatotoxicity by curcumin, rosiglitazone and N-acetylcysteine in rats. Arzneimittel-Forschung, 2010, Volume: 60, Issue:11 Topics: Acetylcysteine; Animals; Anticonvulsants; Body Weight; Chemical and Drug Induced Liver Injury; Convulsants; Curcumin; Eating; Fatty Liver; Free Radical Scavengers; Hypoglycemic Agents; Liver; Liver Function Tests; Male; Mice; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Rosiglitazone; Seizures; Thiazolidinediones; Valproic Acid	2010
A novel cystine based antioxidant attenuates oxidative stress and hepatic steatosis in diet-induced obese mice. Experimental and molecular pathology, 2011, Volume: 91, Issue:1 Topics: Acetylcysteine; Animals; Apolipoproteins E; bcl-2-Associated X Protein; Dietary Fats; Disease Models, Animal; Drug Therapy, Combination; Fatty Liver; Free Radical Scavengers; Hepatocytes; Lipogenesis; Male; MAP Kinase Kinase 4; Mice; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-bcl-2; Selenomethionine	2011
Oxidative stress rather than triglyceride accumulation is a determinant of mitochondrial dysfunction in in vitro models of hepatic cellular steatosis. Liver international : official journal of the International Association for the Study of the Liver, 2012, Volume: 32, Issue:7 Topics: Acetylcysteine; Antioxidants; Cell Line, Tumor; Cell Respiration; Fatty Liver; Gluconeogenesis; Humans; Membrane Potential, Mitochondrial; Mitochondria, Liver; Oxidative Stress; Reactive Oxygen Species; Triglycerides	2012
N-acetylcysteine (NAC) diminishes the severity of PCB 126-induced fatty liver in male rodents. Toxicology, 2012, Dec-08, Volume: 302, Issue:1 Topics: Acetylcysteine; Animals; Antioxidants; CD36 Antigens; Chemical and Drug Induced Liver Injury; Fatty Liver; Gene Expression Regulation; Glutathione; Injections, Intraperitoneal; Male; Organ Size; Polychlorinated Biphenyls; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; Severity of Illness Index	2012
N-Acetylcysteine ameliorates the late phase of liver ischaemia/reperfusion injury in the rabbit with hepatic steatosis. Clinical science (London, England : 1979), 2005, Volume: 109, Issue:5 Topics: Acetylcysteine; Alanine Transaminase; Animals; Bile; Cholesterol, Dietary; Fatty Liver; Hemodynamics; Liver; Liver Circulation; Magnetic Resonance Spectroscopy; Microcirculation; Oxidation-Reduction; Oxidative Stress; Rabbits; Reperfusion Injury	2005
Oral administration of S-nitroso-N-acetylcysteine prevents the onset of non alcoholic fatty liver disease in rats. World journal of gastroenterology, 2006, Mar-28, Volume: 12, Issue:12 Topics: Acetylcysteine; Administration, Oral; Animals; Disease Models, Animal; Fatty Liver; Lipid Peroxidation; Liver; Male; Necrosis; Nitrates; Rats; Rats, Wistar; Transaminases	2006
Hepatic gene expression profile associated with non-alcoholic steatohepatitis protection by S-nitroso-N-acetylcysteine in ob/ob mice. Journal of hepatology, 2006, Volume: 45, Issue:5 Topics: Acetylcysteine; Animals; Antioxidants; Choline Deficiency; Down-Regulation; Fatty Acids; Fatty Liver; Gene Expression Profiling; Lipid Peroxidation; Male; Mice; Models, Animal; Oligonucleotide Array Sequence Analysis; Reactive Oxygen Species; Up-Regulation	2006
Acute fatty liver of pregnancy; three cases and discussion of analgesia and anaesthesia. International journal of obstetric anesthesia, 2007, Volume: 16, Issue:2 Topics: Abdominal Pain; Acetylcysteine; Acute Disease; Adult; Analgesia, Obstetrical; Anesthesia, Obstetrical; Anti-Bacterial Agents; Blood Pressure; Fatty Liver; Female; Fetal Death; Free Radical Scavengers; Gastrointestinal Agents; Humans; Lactulose; Nausea; Pregnancy; Pregnancy Complications; Rare Diseases; Severity of Illness Index; Tachycardia; Vomiting	2007
Effects of N-acetylcysteine on oxidative stress in rats with non-alcoholic steatohepatitis. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2007, Volume: 90, Issue:4 Topics: Acetylcysteine; Animals; Dietary Fats; Disease Models, Animal; Fatty Liver; Free Radical Scavengers; Hepatitis; Liver; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley	2007
Modulation of hepatic microsomal triglyceride transfer protein (MTP) induced by S-nitroso-N-acetylcysteine in ob/ob mice. Biochemical pharmacology, 2007, Jul-15, Volume: 74, Issue:2 Topics: Acetylcysteine; Animals; Carrier Proteins; Fatty Liver; Liver; Male; Mice; Mice, Obese; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger	2007
N-acetylcysteine attenuates oxidative stress and liver pathology in rats with non-alcoholic steatohepatitis. World journal of gastroenterology, 2007, Oct-14, Volume: 13, Issue:38 Topics: Acetylcysteine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Fatty Liver; Free Radical Scavengers; Glutathione; Hepatocytes; Liver; Male; Malondialdehyde; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley	2007
The effects of N-acetylcysteine and anti-intercellular adhesion molecule-1 monoclonal antibody against ischemia-reperfusion injury of the rat steatotic liver produced by a choline-methionine-deficient diet. Hepatology (Baltimore, Md.), 1997, Volume: 26, Issue:3 Topics: Acetylcysteine; Acid Phosphatase; Alanine Transaminase; Animals; Antibodies, Monoclonal; Aspartate Aminotransferases; Bile; Choline Deficiency; Fatty Liver; In Vitro Techniques; Intercellular Adhesion Molecule-1; Ischemia; L-Lactate Dehydrogenase; Liver; Male; Malondialdehyde; Methionine; Microscopy, Electron; Neutrophils; Perfusion; Rats; Rats, Wistar; Reperfusion Injury	1997
N-acetylcysteine and anti-ICAM-1 monoclonal antibody reduce ischemia-reperfusion injury of the steatotic rat liver. Transplantation proceedings, 1998, Volume: 30, Issue:7 Topics: Acetylcysteine; Adenosine; Allopurinol; Animals; Antibodies, Monoclonal; Choline Deficiency; Fatty Liver; Glutathione; Insulin; Intercellular Adhesion Molecule-1; Ischemia; Liver; Male; Methionine; Organ Preservation; Organ Preservation Solutions; Raffinose; Rats; Rats, Wistar; Reperfusion Injury	1998