acetylcysteine has been researched along with Liver Cirrhosis in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.57) | 18.7374 |
| 1990's | 1 (3.57) | 18.2507 |
| 2000's | 7 (25.00) | 29.6817 |
| 2010's | 14 (50.00) | 24.3611 |
| 2020's | 5 (17.86) | 2.80 |
| Authors | Studies |
|---|---|
| Fedrizzi, M; Gál, J; Kovács, E; Maimeri, N; Morselli, F; Orlando, F; Pallanch, O; Székely, A | 1 |
| El-Kharashi, OA; Elayat, WM; Habib, EK; Khairy, E; Khedr, SA; Mohamed, DI | 1 |
| Banerjee, S; Banki, K; Beckford, M; Grossman, CC; Jimah, J; Kansu, A; Kelly, R; Kuloglu, Z; Lee, W; Miklossy, G; Niland, B; Oaks, Z; Perl, A; Szonyi, L | 1 |
| Alukal, J; Amjad, W; Doycheva, I; Maheshwari, A; Thuluvath, PJ; Yoo, H; Zhang, T | 1 |
| Abdallah, FR; Atteia, HH; Elswefy, SE; Hasan, RA; Wahba, AS | 1 |
| Ganz, T; Jung, G; Monga, SP; Nagarajan, S; Poddar, M; Popovic, B; Preziosi, ME; Singh, S; Valore, EV | 1 |
| Chen, A; Guo, Q; Jia, Y; Jiang, S; Jin, H; Li, M; Shao, J; Tan, S; Wang, F; Wang, L; Zhang, F; Zhang, Z; Zheng, S | 1 |
| Adil, HS; Afnan, Q; Bhushan, S; Farrukh, MR; Kaiser, PJ; Nissar, AU; Rafiq, RA; Subhash, BC; Tasduq, SA | 1 |
| Bahcecioglu, IH; Demiroren, K; Dogan, Y; Ilhan, S; Kocamaz, H; Ozercan, IH; Ustundag, B | 1 |
| Fujii, H; Hai, H; Kawada, N; Kubo, S; Matsumoto, Y; Morita, T; Motoyama, H; Suoh, M; Takemura, S; Tamori, A; Thuy, le TT; Thuy, TT; Urahara, Y; Yoshizato, K | 1 |
| Diehl, AM; Jewell, ML; Kruger, L; Machado, MV; Michelotti, GA; Moylan, CA; Pereira, Tde A; Xie, G | 1 |
| Guo, M; Shao, J; Zhang, Z; Zhao, S; Zheng, S | 1 |
| Chen, A; Shao, J; Wang, L; Yao, Z; Zhang, F; Zhang, Z; Zhao, S; Zheng, S | 1 |
| Crespo, I; Cuevas, MJ; de Oliveira, MG; de Souza, GF; González-Gallego, J; Marroni, NP; Tuñón, MJ; Vercelino, R | 1 |
| Kodai, S; Kubo, S; Minamiyama, Y; Okada, S; Osada-Oka, M; Shinkawa, H; Suehiro, S; Takemura, S; Tsukioka, T | 1 |
| Chen, Y; Dalton, TP; Johansson, E; Miller, ML; Nebert, DW; Orlicky, DJ; Shen, D; Shertzer, HG; Vasiliou, V; Yang, Y | 1 |
| Alvares-da-Silva, MR; Carrilho, FJ; Cogliati, B; Lima, VM; Matte, U; Mazo, DC; Oliveira, CP; Santos, F; Silveira, TR; Stefano, JT | 1 |
| Chao, JC; Chen, JR; Lo, YT; Tsai, YH; Wu, SJ | 1 |
| Abdalla, AM; Abdelwahab, SA; Mahmoud, AM; Mahmoud, ME; Morsy, MA | 1 |
| Álvares-da-Silva, MR; Alvares-Dasilva, MR; Camacho, VR; Cerski, CT; de Fraga, RS; de Oliveira, JR; Fraga, RS; Oliveira, JR | 1 |
| Gressner, AM; Lahme, B; Meurer, SK; Tihaa, L; Weiskirchen, R | 1 |
| Borojevic, R; Dal-Pizzol, F; Franceschi, MF; Grivicich, I; Guaragna, RM; Guimarães, EL; Guma, FC; Margis, R; Moreira, JC | 1 |
| Clouzeau-Girard, H; Combe, C; Desmoulière, A; Guyot, C; Moronvalle-Halley, V | 1 |
| Biberoglu, N; Bozbas, A; Eren, F; Gedik, N; Guzel, S; Sahan, E; Tahan, G; Tahan, V; Tarcin, O; Tozun, N; Yucel, O | 1 |
| Hsia, DY; O'Flynn, M; Rowley, WF | 1 |
| Hayes, PC; Jarvie, DR; Jones, AL; Prescott, LF; Simpson, D | 1 |
| Altomare, E; Caruso, ML; Grattagliano, I; Pirrelli, M; Serviddio, G; Valentini, AM; Vendemiale, G | 1 |
| Duan, RD; Liu, JJ; Nilsson, A; Wang, JY; Zhang, C | 1 |
1 review(s) available for acetylcysteine and Liver Cirrhosis
| Article | Year |
|---|---|
Factors improving mortality in critically ill patients with liver failure - A systematic review.
Topics: Acetylcysteine; Adult; Critical Illness; Humans; Liver Cirrhosis; Liver Failure; Liver Failure, Acute | 2023 |
1 trial(s) available for acetylcysteine and Liver Cirrhosis
| Article | Year |
|---|---|
Pharmacokinetics of N-acetylcysteine are altered in patients with chronic liver disease.
Topics: Acetylcysteine; Adult; Aged; Area Under Curve; Biological Availability; Expectorants; Female; Half-Life; Humans; Injections, Intravenous; Liver Cirrhosis; Male; Metabolic Clearance Rate; Middle Aged | 1997 |
26 other study(ies) available for acetylcysteine and Liver Cirrhosis
| Article | Year |
|---|---|
N-acetylcysteine (NAC) alleviates the peripheral neuropathy associated with liver cirrhosis via modulation of neural MEG3/PAR2/ NF-ҡB axis.
Topics: Acetylcysteine; Animals; Free Radical Scavengers; Liver Cirrhosis; Male; NF-kappa B; Peripheral Nervous System Diseases; Random Allocation; Rats; Rats, Wistar; Receptor, PAR-2; RNA, Long Noncoding; Signal Transduction | 2020 |
Transaldolase haploinsufficiency in subjects with acetaminophen-induced liver failure.
Topics: Acetylcysteine; Adult; Animals; Carcinoma, Hepatocellular; Female; Haploinsufficiency; Humans; Liver Cirrhosis; Liver Failure; Liver Neoplasms; Male; Mice; Mice, Knockout; Mitochondria; Oxidative Stress; Pentose Phosphate Pathway; Transaldolase; Young Adult | 2020 |
A Combination of N-Acetylcysteine and Prednisone Has No Benefit Over Prednisone Alone in Severe Alcoholic Hepatitis: A Retrospective Analysis.
Topics: Acetylcysteine; Adult; Anti-Inflammatory Agents; Drug Monitoring; Drug Therapy, Combination; Female; Free Radical Scavengers; Hepatitis, Alcoholic; Humans; Liver Cirrhosis; Male; Outcome and Process Assessment, Health Care; Prednisone; Renal Insufficiency; Survival Analysis; United States | 2020 |
Antifibrotic effect of curcumin, N-acetyl cysteine and propolis extract against bisphenol A-induced hepatotoxicity in rats: Prophylaxis versus co-treatment.
Topics: Acetylcysteine; Animals; Apoptosis; Benzhydryl Compounds; Chemical and Drug Induced Liver Injury; Curcumin; Drug Therapy, Combination; Inflammation; Interleukins; Liver; Liver Cirrhosis; Male; Phenols; Propolis; Rats; Rats, Wistar | 2020 |
Mice lacking liver-specific β-catenin develop steatohepatitis and fibrosis after iron overload.
Topics: Acetylcysteine; Animals; Antioxidants; beta Catenin; Disease Models, Animal; Fatty Liver; Female; Hemochromatosis; Humans; Iron Overload; Liver; Liver Cirrhosis; Male; Mice; Mice, Knockout; Oxidative Stress; Signal Transduction | 2017 |
Curcumol induces RIPK1/RIPK3 complex-dependent necroptosis via JNK1/2-ROS signaling in hepatic stellate cells.
Topics: Acetylcysteine; Animals; Carbon Tetrachloride; Cell Proliferation; Cells, Cultured; Hepatic Stellate Cells; Liver Cirrhosis; Male; Mice; Mice, Inbred ICR; Mitochondria; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Necrosis; Phosphorylation; Random Allocation; Reactive Oxygen Species; Receptor-Interacting Protein Serine-Threonine Kinases; RNA Interference; RNA, Small Interfering; Sesquiterpenes | 2018 |
Effect of N-acetyl cysteine (NAC), an organosulfur compound from Allium plants, on experimentally induced hepatic prefibrogenic events in Wistar rat.
Topics: Acetylcysteine; Allium; Animals; Carbon Tetrachloride; Disease Models, Animal; Liver Cirrhosis; Male; Oxidative Stress; Phytotherapy; Rats; Rats, Wistar; Sulfur; Thioacetamide | 2013 |
Protective effects of L-carnitine, N-acetylcysteine and genistein in an experimental model of liver fibrosis.
Topics: Acetylcysteine; Animals; Carnitine; Disease Models, Animal; Genistein; Liver Cirrhosis; Male; Rats; Rats, Wistar | 2014 |
Cytoglobin deficiency promotes liver cancer development from hepatosteatosis through activation of the oxidative stress pathway.
Topics: Acetylcysteine; Animals; Antioxidants; Cytoglobin; Diet; Globins; Hepatic Stellate Cells; Humans; Inflammation; Liver; Liver Cirrhosis; Liver Neoplasms; Macrophages; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Oxidation-Reduction; Oxidative Stress; Precancerous Conditions | 2015 |
Vitamin B5 and N-Acetylcysteine in Nonalcoholic Steatohepatitis: A Preclinical Study in a Dietary Mouse Model.
Topics: Acetylcysteine; Acyl Coenzyme A; Animals; Apoptosis; Caspase 2; Choline Deficiency; Diet, Western; Disease Models, Animal; Liver; Liver Cirrhosis; Male; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor); Vitamin B Complex | 2016 |
ROS-JNK1/2-dependent activation of autophagy is required for the induction of anti-inflammatory effect of dihydroartemisinin in liver fibrosis.
Topics: Acetylcysteine; Animals; Anthracenes; Anti-Inflammatory Agents; Antioxidants; Artemisinins; Autophagy; Carbon Tetrachloride; Gene Expression Regulation; Glutathione; Hepatic Stellate Cells; Humans; Liver; Liver Cirrhosis; Male; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Small Interfering | 2016 |
Autophagy regulates turnover of lipid droplets via ROS-dependent Rab25 activation in hepatic stellate cell.
Topics: Acetylcysteine; Animals; Antioxidants; Autophagy; Autophagy-Related Protein 5; Class III Phosphatidylinositol 3-Kinases; Gene Expression Regulation; Glutathione; Hepatic Stellate Cells; Lipid Droplets; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred ICR; Primary Cell Culture; Proteins; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction | 2017 |
S-nitroso-N-acetylcysteine attenuates liver fibrosis in cirrhotic rats.
Topics: Acetylcysteine; Animals; Antioxidants; Fibrosis; Immunohistochemistry; Lipid Peroxidation; Liver; Liver Cirrhosis; Male; MAP Kinase Signaling System; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase | 2010 |
S-allylcysteine is effective as a chemopreventive agent against porcine serum-induced hepatic fibrosis in rats.
Topics: Acetylcysteine; Actins; Alanine Transaminase; Animals; Anticarcinogenic Agents; Chemoprevention; Cysteine; Disease Models, Animal; Hepatic Stellate Cells; Lipid Peroxidation; Liver; Liver Cirrhosis; Male; Rats; Rats, Wistar; Serum; Sulfhydryl Compounds; Swine; Treatment Outcome | 2009 |
Oral N-acetylcysteine rescues lethality of hepatocyte-specific Gclc-knockout mice, providing a model for hepatic cirrhosis.
Topics: Acetylcysteine; Administration, Oral; Animals; Antioxidants; Base Sequence; Cytokines; Disease Models, Animal; DNA Primers; Gene Expression Profiling; Glutamate-Cysteine Ligase; Glutathione; Hepatocytes; Liver; Liver Cirrhosis; Mice; Mice, Knockout; Microscopy, Electron, Transmission; Mitochondria, Liver; Oxidative Stress; RNA, Messenger | 2010 |
S-Nitroso-N-acetylcysteine induces de-differentiation of activated hepatic stellate cells and promotes antifibrotic effects in vitro.
Topics: Acetylcysteine; Animals; Cell Dedifferentiation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Hepatic Stellate Cells; Liver Cirrhosis; Mice | 2011 |
Ginsenoside Rb1 inhibits cell activation and liver fibrosis in rat hepatic stellate cells.
Topics: Acetylcysteine; Animals; Cell Line; Cell Proliferation; Cell Survival; Collagen; Dimethyl Sulfoxide; Ginsenosides; Hepatic Stellate Cells; Hydrogen Peroxide; Liver Cirrhosis; Matrix Metalloproteinase 2; Oxidative Stress; Rats; Taiwan; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1 | 2011 |
Protective effects of curcumin, α-lipoic acid, and N-acetylcysteine against carbon tetrachloride-induced liver fibrosis in rats.
Topics: Acetylcysteine; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Bilirubin; Carbon Tetrachloride; Curcumin; gamma-Glutamyltransferase; Glutathione; Liver Cirrhosis; Male; Malondialdehyde; Matrix Metalloproteinase 13; Rats; Rats, Wistar; Thioctic Acid; Transforming Growth Factor alpha | 2012 |
Relationship between ischemia/reperfusion injury and the stimulus of fibrogenesis in an experimental model: comparison among different preservation solutions.
Topics: Acetylcysteine; Adenosine; Alanine Transaminase; Allopurinol; Animals; Aspartate Aminotransferases; Biomarkers; Catalase; Disease Models, Animal; Fructosediphosphates; Glutathione; Insulin; L-Lactate Dehydrogenase; Liver; Liver Cirrhosis; Liver Transplantation; Male; Organ Preservation Solutions; Raffinose; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin; Reperfusion Injury; Thiobarbituric Acid Reactive Substances; Time Factors; Transforming Growth Factor beta1 | 2011 |
N-acetyl-L-cysteine suppresses TGF-beta signaling at distinct molecular steps: the biochemical and biological efficacy of a multifunctional, antifibrotic drug.
Topics: Acetylcysteine; Animals; Blotting, Western; COS Cells; DNA-Binding Proteins; Liver Cirrhosis; Male; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Signal Transduction; Smad7 Protein; Trans-Activators; Transforming Growth Factor beta | 2005 |
Relationship between oxidative stress levels and activation state on a hepatic stellate cell line.
Topics: Acetylcysteine; Animals; Antioxidants; Catalase; Cell Line; Cell Proliferation; Chromans; Cytokines; Liver; Liver Cirrhosis; Mice; Oxidative Stress; Phenotype; Reactive Oxygen Species; Tumor Necrosis Factor-alpha; Vitamin E | 2006 |
Specific activation of the different fibrogenic cells in rat cultured liver slices mimicking in vivo situations.
Topics: Acetaminophen; Acetylcysteine; Animal Use Alternatives; Animals; Antioxidants; Bile Ducts, Intrahepatic; Cell Survival; Disease Models, Animal; Drug Antagonism; Epidermal Growth Factor; Estradiol; Fibroblasts; Hepatocytes; Kupffer Cells; Liver; Liver Cirrhosis; Male; Necrosis; Organ Culture Techniques; Portal System; Rats; Rats, Wistar; Thioacetamide | 2007 |
The effects of N-acetylcysteine on bile duct ligation-induced liver fibrosis in rats.
Topics: Acetylcysteine; Animals; Bile Ducts; Collagen; Disease Models, Animal; Free Radical Scavengers; Glutathione; Ligation; Liver Cirrhosis; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Spectrophotometry | 2007 |
Cystic fibrosis of the pancreas.
Topics: Acetylcysteine; Anti-Bacterial Agents; Bronchi; Bronchial Diseases; Child; Cystic Fibrosis; Digestive System; Drainage; Fecal Impaction; Humans; Hyperglycemia; Intestinal Obstruction; Liver Cirrhosis; Lung; Lung Diseases; Meconium; Mucus; Pneumatosis Cystoides Intestinalis; Respiratory Function Tests; Respiratory Insufficiency; Respiratory Therapy; Respiratory Tract Diseases; Salivary Glands; Sweat | 1966 |
Increased oxidative stress in dimethylnitrosamine-induced liver fibrosis in the rat: effect of N-acetylcysteine and interferon-alpha.
Topics: Acetylcysteine; Animals; Dimethylnitrosamine; Free Radical Scavengers; Interferon-alpha; Liver Cirrhosis; Male; Oxidative Stress; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances | 2001 |
Hepatic cirrhosis increases sensitivity of kidney to endotoxin in rats.
Topics: Acetylcysteine; Animals; Endotoxins; Kidney; Liver Cirrhosis; Rats; Rats, Sprague-Dawley | 2002 |