acetylcysteine has been researched along with Leukemia in 46 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.17) | 18.7374 |
| 1990's | 2 (4.35) | 18.2507 |
| 2000's | 15 (32.61) | 29.6817 |
| 2010's | 24 (52.17) | 24.3611 |
| 2020's | 4 (8.70) | 2.80 |
| Authors | Studies |
|---|---|
| Dolezel, P; Kriegova, E; Mlejnek, P; Pastvova, N | 1 |
| Chen, Y; Gao, A; Guo, X; Ren, J; Wang, J; Zhang, L; Zhang, W; Zhang, Y | 1 |
| Bartoccini, F; Crinelli, R; Diotallevi, A; Fraternale, A; Galluzzi, L; Magnani, M; Masini, S; Monittola, F; Smietana, M | 1 |
| Gurunathan, S; Jeyaraj, M; Kang, MH; Kim, JH | 1 |
| Lee, Y; Park, HB; Park, JA; Park, S; Yoo, H | 1 |
| Dolezel, P; Mlejnek, P; Ruzickova, E; Skoupa, N | 1 |
| Chen, YC; El-Shazly, M; Hsu, YM; Lai, KH; Lee, YL; Liu, YC; Lu, MC; Wu, TY | 1 |
| Choi, YH; Jin, CY; Kim, GY; Kim, WJ; Kwon, TK; Molagoda, IMN; Park, C; Yun, SJ | 1 |
| Ge, Y; Gu, N; Guo, D; Huang, Z; Ma, W; Wu, J; Zhang, X; Zhang, Y; Zhao, Y; Zhou, H; Zhou, X; Zhu, L | 1 |
| Anderson, LM; Holland, RJ; Keefer, LK; Maciag, AE; Robert Cheng, YS; Rodriguez, LG; Saavedra, JE | 1 |
| Leung, AW; Li, Y; Liu, Q; Su, X; Wang, P; Wang, X; Xu, C | 1 |
| Ho, CT; Huang, LJ; Kuo, DH; Kuo, SC; Lee, JC; Lin, YC; Liu, YJ; Way, TD | 1 |
| Kim, YE; Kwon, HJ; Lee, Y; Park, JA; Park, S; Song, S | 1 |
| Cho, EW; Kim, IG; Kim, JS; Lee, JH | 1 |
| Ando, M; Itoh, T; Koketsu, M; Masu, M; Muramatsu, Y; Ninomiya, M; Taniguchi, M; Tsuge, A; Tsukamasa, Y | 1 |
| Chandra, J; Egas-Bejar, DE; Fulbright, JM; Huh, WW | 1 |
| Li, Y; Liu, J; Ma, X; Ye, BC; Zhang, B; Zuo, P | 1 |
| Boris, SP; Popruzhenko, ТV | 1 |
| Berger, W; Downey, T; Heffeter, P; Herbacek, I; Jha, AK; Kril, IJ; Lehka, LV; Matselyukh, BP; Panchuk, RR; Rohr, J; Stoika, RS; Terenzi, A; van Schoonhoven, S | 1 |
| Chen, J; Jia, J | 1 |
| Ekberg, J; Persson, JL | 1 |
| Brown, GC; Brown, RD; Burke, GA | 1 |
| Chen, C; Liu, Y; Zheng, D | 1 |
| Choi, JH; Lee, KT | 1 |
| Deng, Y; Jing, Y; Li, Y; Ma, E; Wang, R; Wang, X; Xiao, J | 1 |
| Ahn, G; Heo, SJ; Jeon, YJ; Kang, SM; Kim, KN | 1 |
| Tang, X; Wang, C; Xiao, G; Yao, C | 1 |
| Finn, NA; Kemp, ML | 1 |
| Jiang, YF; Qu, SC; Qu, XR; Sui, da Y; Xu, HL; Yu, XF | 1 |
| Chang, WY; Choi, YH; Hyun, JW; Jayasooriya, RG; Kang, CH; Kang, SH; Kim, GY; Moon, DO | 1 |
| Choi, YH; Han, MH; Kang, HS; Kim, GY; Kim, WJ; Park, YS; Shin, DY; Yang, K | 1 |
| Cheng, YY; Chien, HC; Chung, JG; Huang, LJ; Kuo, SC; Lee, KH; Liaw, CC; Lu, CC; Tsai, SC; Tsuzuki, M; Yang, JS | 1 |
| Akatsuka, Y; Demachi-Okamura, A; Kuzushima, K; Miyoshi, H; Torikai, H; Yoshimori, T | 1 |
| Bezombes, C; Demur, C; Filomenko, R; Hernandez, H; Jaffrézou, JP; Laurent, G; Maestre, N; Mas, VM; Plo, I; Quillet-Mary, A | 1 |
| Adjei, AA; Bone, N; Bruzek, LM; Chandra, J; Hackbarth, J; Karp, JE; Kaufmann, SH; Kay, NE; Le, S; Loegering, D; Narayanan, VL; Sausville, EA; Tefferi, A | 1 |
| Chen, J; Da, W; Kang, J; Ou, Y | 1 |
| Chen, J; Kang, J; Liu, Q; Wanming, D; Zhang, D | 1 |
| Hamasu, T; Inanami, O; Kashiwakura, I; Kuwabara, M; Takahashi, E; Tsujitani, M; Yokoyama, K | 1 |
| Hibasami, H; Iwase, H; Takahashi, H; Yoshioka, K | 1 |
| Efferth, T; Giaisi, M; Krammer, PH; Li-Weber, M; Merling, A | 1 |
| Arranz, N; Delgado, E; García, A; Haza, AI; Morales, P; Rafter, J | 1 |
| Hsu, PC; Hung, HC; Liao, YF; Liu, CC; Liu, GY; Tsay, GJ | 1 |
| Adesida, A; Edwards, LG; Thornalley, PJ | 1 |
| Chen, BD; Chen, C; Lin, H; Zhang, XM | 1 |
| Hauptmann, S; Leclere, A; Naujokat, C; Possinger, K; Sezer, O; Zinke, H | 1 |
| Arapakis, G; Gardikas, C; Kirkou, K; Stathakis, N | 1 |
1 trial(s) available for acetylcysteine and Leukemia
| Article | Year |
|---|---|
[Salivation in children during anticancer chemotherapy].
Topics: Acetylcysteine; Antimetabolites, Antineoplastic; Child; Cross-Sectional Studies; Dose-Response Relationship, Drug; Expectorants; Humans; Leukemia; Methotrexate; Saliva; Salivation; Viscosity | 2016 |
45 other study(ies) available for acetylcysteine and Leukemia
| Article | Year |
|---|---|
N-acetylcysteine Can Induce Massive Oxidative Stress, Resulting in Cell Death with Apoptotic Features in Human Leukemia Cells.
Topics: Acetylcysteine; Catalase; Cell Proliferation; Cell Survival; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Leukemia; NADPH Oxidase 2; Oxidative Stress; Peroxidase; Reactive Oxygen Species; Superoxide Dismutase; U937 Cells | 2021 |
Plasma metabolomics study reveals the critical metabolic signatures for benzene-induced hematotoxicity.
Topics: Acetylcysteine; Animals; Benzene; Bone Diseases, Metabolic; Fatty Acids; Humans; Leukemia; Leukocytes; Lipid Metabolism; Metabolic Networks and Pathways; Metabolomics; Mice; Occupational Exposure; Oxidation-Reduction | 2022 |
A synthetic thiol molecule releasing N-acetyl-l-cysteine and cysteamine drives early up-regulation of immunoproteasome subunits in the lymph nodes of mice infected with LP-BM5 leukemia retrovirus.
Topics: Acetylcysteine; Animals; Cysteamine; Leukemia; Lymph Nodes; Mice; Murine Acquired Immunodeficiency Syndrome; Retroviridae; Sulfhydryl Compounds; Up-Regulation | 2024 |
Palladium Nanoparticle-Induced Oxidative Stress, Endoplasmic Reticulum Stress, Apoptosis, and Immunomodulation Enhance the Biogenesis and Release of Exosome in Human Leukemia Monocytic Cells (THP-1).
Topics: Acetylcholinesterase; Acetylcysteine; Aniline Compounds; Antioxidants; Apoptosis; Benzylidene Compounds; Biomarkers, Tumor; Caspases; Cell Proliferation; Cell Survival; Cytokines; DNA Damage; Endoplasmic Reticulum Stress; Enzyme Activation; Exosomes; Gene Expression Regulation, Leukemic; Humans; Immunomodulation; Leukemia; Metal Nanoparticles; Mitochondria; Neoplasm Proteins; Oxidative Stress; Palladium; Particle Size; Sphingomyelin Phosphodiesterase; THP-1 Cells | 2021 |
Proteasome inhibitor-induced cleavage of HSP90 is mediated by ROS generation and caspase 10-activation in human leukemic cells.
Topics: Acetylcysteine; Carrier Proteins; Caspase 10; Free Radical Scavengers; Glutathione; HCT116 Cells; HSP90 Heat-Shock Proteins; HT29 Cells; Humans; Leukemia; Leupeptins; MCF-7 Cells; Protease Inhibitors; Proteolysis; Reactive Oxygen Species | 2017 |
Apoptosis Induced by the Curcumin Analogue EF-24 Is Neither Mediated by Oxidative Stress-Related Mechanisms nor Affected by Expression of Main Drug Transporters ABCB1 and ABCG2 in Human Leukemia Cells.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; Benzylidene Compounds; Cell Line, Tumor; Glutathione; Humans; Leukemia; Neoplasm Proteins; Oxidative Stress; Piperidones; Reactive Oxygen Species | 2017 |
Breaking down Leukemia Walls: Heteronemin, a Sesterterpene Derivative, Induces Apoptosis in Leukemia Molt4 Cells through Oxidative Stress, Mitochondrial Dysfunction and Induction of Talin Expression.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; HEK293 Cells; Humans; Leukemia; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Oxidative Stress; Porifera; Reactive Oxygen Species; RNA, Small Interfering; Sesterterpenes; Talin; Terpenes; Xenograft Model Antitumor Assays | 2018 |
Piceatannol-Induced Apoptosis Is Reversed by N-Acetyl-L-cysteine through Restoration of XIAP Expression.
Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Down-Regulation; Humans; Leukemia; Stilbenes; X-Linked Inhibitor of Apoptosis Protein | 2018 |
Anti-leukemia activity of PVP-coated silver nanoparticles via generation of reactive oxygen species and release of silver ions.
Topics: Acetylcysteine; Adolescent; Adult; Aged; Antineoplastic Agents; Antioxidants; Apoptosis; Ascorbic Acid; Cell Line, Tumor; DNA Damage; Female; HL-60 Cells; Humans; Ions; Leukemia; Male; Membrane Potential, Mitochondrial; Metal Nanoparticles; Middle Aged; Reactive Oxygen Species; Silver | 2013 |
Nitric oxide-releasing prodrug triggers cancer cell death through deregulation of cellular redox balance.
Topics: Acetylcysteine; Azo Compounds; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Leukemia; Membrane Potential, Mitochondrial; Nitric Oxide; Nitric Oxide Donors; Oxidation-Reduction; Piperazines; Prodrugs; Reactive Nitrogen Species | 2013 |
Cytotoxic effect of protoporphyrin IX to human Leukemia U937 cells under ultrasonic irradiation.
Topics: Acetylcysteine; Apoptosis; DNA; DNA Fragmentation; Humans; Leukemia; Membrane Potential, Mitochondrial; Mitochondria; Protoporphyrins; Reactive Oxygen Species; Sonication; U937 Cells | 2014 |
CCT327 enhances TRAIL-induced apoptosis through the induction of death receptors and downregulation of cell survival proteins in TRAIL-resistant human leukemia cells.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Proliferation; Drug Resistance, Neoplasm; HL-60 Cells; Humans; Leukemia; Organoselenium Compounds; Quinolines; Quinolones; Reactive Oxygen Species; Receptors, Death Domain; TNF-Related Apoptosis-Inducing Ligand; Up-Regulation | 2014 |
Suberoylanilide hydroxamic acid induces ROS-mediated cleavage of HSP90 in leukemia cells.
Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Caspase 10; Caspase Inhibitors; Caspases; fas Receptor; Histone Deacetylase Inhibitors; HSP90 Heat-Shock Proteins; Humans; Hydrogen Peroxide; Hydroxamic Acids; K562 Cells; Leukemia; Proteolysis; Reactive Oxygen Species; Signal Transduction; Vorinostat | 2015 |
Genistein decreases cellular redox potential, partially suppresses cell growth in HL‑60 leukemia cells and sensitizes cells to γ‑radiation‑induced cell death.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Cell Cycle Checkpoints; Cell Death; Cell Division; Cell Line, Tumor; Cell Proliferation; Down-Regulation; G2 Phase; Gamma Rays; Genistein; HL-60 Cells; Humans; Isocitrate Dehydrogenase; Leukemia; Lymphocytes; NADP; Oxidation-Reduction; Reactive Oxygen Species; Up-Regulation | 2014 |
A synthesized nostocionone derivative potentiates programmed cell death in human T-cell leukemia Jurkat cells through mitochondria via the release of endonuclease G.
Topics: Acetylcysteine; Apoptosis; DNA Fragmentation; Endodeoxyribonucleases; Humans; Jurkat Cells; Leukemia; Membrane Potential, Mitochondrial; Mitochondria; Nostoc commune; Reactive Oxygen Species | 2014 |
Analysis of redox and apoptotic effects of anthracyclines to delineate a cardioprotective strategy.
Topics: Acetylcysteine; Acute Disease; Adolescent; Animals; Anthracyclines; Antioxidants; Apoptosis; Cardiotonic Agents; Cell Line; Cell Line, Tumor; Child, Preschool; Female; Heart Diseases; Humans; Jurkat Cells; Leukemia; Leukocytes, Mononuclear; Male; Mice, Inbred BALB C; Mice, SCID; Myocytes, Cardiac; Oxidation-Reduction; Oxidative Stress; Rats; Reactive Oxygen Species | 2015 |
Ultrasensitive and selective assay of glutathione species in arsenic trioxide-treated leukemia HL-60 cell line by molecularly imprinted polymer decorated electrochemical sensors.
Topics: Acetylcysteine; Arsenic Trioxide; Arsenicals; Biosensing Techniques; Dielectric Spectroscopy; Glutathione; Glutathione Disulfide; HL-60 Cells; Humans; Leukemia; Molecular Imprinting; Oxides; Polymers | 2016 |
Rapid generation of hydrogen peroxide contributes to the complex cell death induction by the angucycline antibiotic landomycin E.
Topics: Acetylcysteine; Aminoglycosides; Antibiotics, Antineoplastic; Apoptosis; Caspase 7; Caspase 9; Doxorubicin; Humans; Hydrogen Peroxide; Jurkat Cells; Leukemia; Mitochondria; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Reactive Oxygen Species; Streptomyces; Superoxides | 2017 |
Histone hyperacetylation is involved in the quercetin-induced human leukemia cell death.
Topics: Acetylation; Acetylcysteine; Cell Death; Cell Proliferation; Free Radical Scavengers; Histones; HL-60 Cells; Humans; Hydroxamic Acids; Leukemia; Lipid Peroxidation; Malondialdehyde; Quercetin; Reactive Oxygen Species | 2008 |
Post-translational modification of cyclin A1 is associated with staurosporine and TNFalpha induced apoptosis in leukemic cells.
Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase 3; Caspase Inhibitors; cdc25 Phosphatases; Cell Line, Tumor; Cyclin A1; Cyclin-Dependent Kinase 2; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Humans; Leukemia; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Processing, Post-Translational; Staurosporine; Tumor Necrosis Factor-alpha; Ubiquitination | 2009 |
Dependence of leukemic cell proliferation and survival on H2O2 and L-arginine.
Topics: Acetylcysteine; Antioxidants; Arginase; Arginine; Ascorbic Acid; Azoles; Catalase; Cell Death; Cell Line, Tumor; Cell Proliferation; Humans; Hydrogen Peroxide; Isoindoles; Leukemia; Organoselenium Compounds | 2009 |
An agonistic monoclonal antibody against DR5 induces ROS production, sustained JNK activation and Endo G release in Jurkat leukemia cells.
Topics: Acetylcysteine; Antibodies, Monoclonal; Apoptosis; Caspase 8; Cell Line, Tumor; Endodeoxyribonucleases; Humans; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; Leukemia; Membrane Potential, Mitochondrial; Mitochondria; NF-kappa B; Reactive Oxygen Species; Receptors, TNF-Related Apoptosis-Inducing Ligand; Signal Transduction | 2009 |
Costunolide-induced apoptosis in human leukemia cells: involvement of c-jun N-terminal kinase activation.
Topics: Acetylcysteine; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Lewis Lung; Drug Therapy, Combination; Free Radical Scavengers; Humans; JNK Mitogen-Activated Protein Kinases; Leukemia; Magnolia; Mice; Phytotherapy; Plant Bark; Plant Extracts; Plant Stems; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Sesquiterpenes; Signal Transduction; Sorbitol; U937 Cells | 2009 |
The induction of G2/M cell-cycle arrest and apoptosis by cucurbitacin E is associated with increased phosphorylation of eIF2alpha in leukemia cells.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 3; Caspase 8; Caspase 9; Catalase; Cell Cycle; Cell Division; Eukaryotic Initiation Factor-2; G2 Phase; Growth Inhibitors; Humans; Inhibitor of Apoptosis Proteins; Jurkat Cells; Leukemia; Microtubule-Associated Proteins; Myeloid Cell Leukemia Sequence 1 Protein; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Survivin; Triterpenes; X-Linked Inhibitor of Apoptosis Protein | 2010 |
Fucoxanthin induces apoptosis in human leukemia HL-60 cells through a ROS-mediated Bcl-xL pathway.
Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-X Protein; Caspase Inhibitors; Caspases; Cell Cycle; Cell Nucleus; Cell Survival; Drug Antagonism; Free Radical Scavengers; HL-60 Cells; Humans; Leukemia; Phaeophyceae; Plant Extracts; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Signal Transduction; Xanthophylls | 2010 |
Potentiation of arsenic trioxide-induced apoptosis by 8-bromo-7-methoxychrysin in human leukemia cells involves depletion of intracellular reduced glutathione.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; bcl-2-Associated X Protein; bcl-X Protein; Blotting, Western; Cell Survival; Cytochromes c; Dose-Response Relationship, Drug; Drug Synergism; Flavonoids; Glutathione; HL-60 Cells; Humans; Intracellular Space; Jurkat Cells; Leukemia; Mitochondria; Oxides; Phosphorylation; Proto-Oncogene Proteins c-akt; Time Factors; U937 Cells; X-Linked Inhibitor of Apoptosis Protein | 2011 |
Pro-oxidant and antioxidant effects of N-acetylcysteine regulate doxorubicin-induced NF-kappa B activity in leukemic cells.
Topics: Acetylcysteine; Antioxidants; Cell Line, Tumor; Doxorubicin; Glutathione; Humans; I-kappa B Kinase; Leukemia; NF-kappa B; Oxidation-Reduction; Reactive Oxygen Species | 2012 |
Juglone, from Juglans mandshruica Maxim, inhibits growth and induces apoptosis in human leukemia cell HL-60 through a reactive oxygen species-dependent mechanism.
Topics: Acetylcysteine; Annexin A5; Antioxidants; Apoptosis; Caspases; Cell Division; Cytochromes c; Enzyme Activation; Glutathione; HL-60 Cells; Humans; Juglans; Leukemia; Membrane Potentials; Naphthoquinones; Reactive Oxygen Species | 2012 |
Apigenin decreases cell viability and telomerase activity in human leukemia cell lines.
Topics: Acetylcysteine; Apigenin; Apoptosis; Base Sequence; Cell Line, Tumor; Cell Survival; DNA Primers; Electrophoretic Mobility Shift Assay; Flow Cytometry; Glutathione; Humans; Leukemia; Reactive Oxygen Species; Telomerase | 2012 |
Decitabine, a DNA methyltransferase inhibitor, induces apoptosis in human leukemia cells through intracellular reactive oxygen species generation.
Topics: Acetylcysteine; Apoptosis; Azacitidine; Baculoviral IAP Repeat-Containing 3 Protein; Caspases; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Decitabine; Down-Regulation; Enzyme Inhibitors; Humans; Inhibitor of Apoptosis Proteins; Leukemia; Membrane Potential, Mitochondrial; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Ubiquitin-Protein Ligases; X-Linked Inhibitor of Apoptosis Protein | 2012 |
The newly synthesized 2-(3-hydroxy-5-methoxyphenyl)-6,7-methylenedioxyquinolin-4-one triggers cell apoptosis through induction of oxidative stress and upregulation of the p38 MAPK signaling pathway in HL-60 human leukemia cells.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Benzodioxoles; Caspases; Cell Survival; fas Receptor; Free Radical Scavengers; HL-60 Cells; Humans; Leukemia; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Quinolones; Reactive Oxygen Species; Signal Transduction; Up-Regulation | 2012 |
Autophagy creates a CTL epitope that mimics tumor-associated antigens.
Topics: Acetylcysteine; Aminopeptidases; Antigens, Neoplasm; Autophagy; Cell Line, Tumor; Epitopes; Fibroblasts; HLA-A24 Antigen; Humans; Leukemia; Molecular Mimicry; Pancreatic Neoplasms; Recombinant Proteins; RNA Interference; T-Lymphocytes, Cytotoxic; Vacuoles | 2012 |
Protein kinase Czeta mediated Raf-1/extracellular-regulated kinase activation by daunorubicin.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcysteine; Androstadienes; Antibiotics, Antineoplastic; Antioxidants; Bridged-Ring Compounds; Cell Death; Daunorubicin; Diglycerides; Enzyme Activation; Flavonoids; Humans; Leukemia; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Norbornanes; Phosphatidylcholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-raf; Reactive Oxygen Species; Thiocarbamates; Thiones; Transfection; Tumor Cells, Cultured; Wortmannin | 2003 |
Involvement of reactive oxygen species in adaphostin-induced cytotoxicity in human leukemia cells.
Topics: Acetylcysteine; Adamantane; Antioxidants; Apoptosis; Buthionine Sulfoximine; DNA Damage; DNA, Neoplasm; Enzyme Inhibitors; Fusion Proteins, bcr-abl; Glutathione; Humans; Hydroquinones; K562 Cells; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Neoplasm Proteins; Neoplastic Stem Cells; Quinones; Reactive Oxygen Species; Tumor Stem Cell Assay; Tyrphostins | 2003 |
Combination with water-soluble antioxidants increases the anticancer activity of quercetin in human leukemia cells.
Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Ascorbic Acid; Cell Proliferation; Cell Survival; Glutathione; HL-60 Cells; Humans; Hydrogen Peroxide; Indicators and Reagents; Leukemia; Lipid Peroxidation; Malondialdehyde; Quercetin; Reactive Oxygen Species; Solubility | 2004 |
Water-soluble antioxidants improve the antioxidant and anticancer activity of low concentrations of curcumin in human leukemia cells.
Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Ascorbic Acid; Cell Proliferation; Cell Survival; Curcumin; Glutathione; HL-60 Cells; Humans; Hydrogen Peroxide; Indicators and Reagents; Leukemia; Lipid Peroxidation; Malondialdehyde; Oxidants; Reactive Oxygen Species | 2005 |
Post-irradiation hypoxic incubation of X-irradiated MOLT-4 cells reduces apoptotic cell death by changing the intracellular redox state and modulating SAPK/JNK pathways.
Topics: Acetylcysteine; Apoptosis; Caspase 3; Caspases; Cell Line, Tumor; Enzyme Activation; fas Receptor; Glutathione; Humans; Hypoxia; Imidazoles; Leukemia; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Radiation-Sensitizing Agents | 2005 |
Glycyrrhetic acid (a metabolic substance and aglycon of glycyrrhizin) induces apoptosis in human hepatoma, promyelotic leukemia and stomach cancer cells.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; Leukemia; Lymphocytes; Stomach Neoplasms | 2006 |
Artesunate induces ROS-mediated apoptosis in doxorubicin-resistant T leukemia cells.
Topics: Acetylcysteine; Animals; Antibiotics, Antineoplastic; Antimalarials; Apoptosis; Artemisinins; Artesunate; Cell Line, Tumor; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Free Radical Scavengers; Humans; Leukemia; Mice; Oxidation-Reduction; Reactive Oxygen Species | 2007 |
Induction of apoptosis and reactive oxygen species production by N-nitrosopiperidine and N-nitrosodibutylamine in human leukemia cells.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Blotting, Western; Carcinogens; Cell Shape; Cell Survival; Chromatin Assembly and Disassembly; Dose-Response Relationship, Drug; Flow Cytometry; HL-60 Cells; Humans; In Situ Nick-End Labeling; Leukemia; Nitrosamines; Oxidative Stress; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Time Factors | 2008 |
Ornithine decarboxylase attenuates leukemic chemotherapy drugs-induced cell apoptosis and arrest in human promyelocytic HL-60 cells.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Caspases; Cell Cycle; Cisplatin; Etoposide; Glutathione; HL-60 Cells; Humans; Leukemia; Membrane Potential, Mitochondrial; Ornithine Decarboxylase; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; Putrescine; Reactive Oxygen Species | 2008 |
Inhibition of human leukaemia 60 cell growth by mercapturic acid metabolites of phenylethyl isothiocyanate.
Topics: Acetylcysteine; Antineoplastic Agents; Cell Division; DNA; Humans; Isocyanates; Leukemia; Tumor Cells, Cultured | 1996 |
Inhibition of ubiquitin-proteasome pathway activates a caspase-3-like protease and induces Bcl-2 cleavage in human M-07e leukaemic cells.
Topics: Acetylcysteine; Apoptosis; Caspase 3; Caspase Inhibitors; Caspases; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Enzyme Activation; Enzyme Precursors; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia; Leupeptins; Molecular Weight; Multienzyme Complexes; Oligopeptides; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Signal Transduction; Time Factors; Tumor Cells, Cultured; Ubiquitins | 1999 |
Proteasome inhibitors induced caspase-dependent apoptosis and accumulation of p21WAF1/Cip1 in human immature leukemic cells.
Topics: Acetylcysteine; Acute Disease; Adult; Antigens, CD34; Apoptosis; Caspase 3; Caspases; Cell Culture Techniques; Cell Cycle; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Flow Cytometry; G2 Phase; Hematopoietic Stem Cells; Humans; K562 Cells; Leukemia; Leupeptins; Mitosis; Multienzyme Complexes; Neoplasm Proteins; Tumor Cells, Cultured; Tumor Suppressor Protein p53; U937 Cells | 2000 |
Lysis of red cells from haematological disorders.
Topics: Acetylcysteine; Acute Disease; Anemia, Aplastic; Erythrocytes; Hemolysis; Histological Techniques; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Myeloproliferative Disorders; Thalassemia | 1972 |