acetylcysteine and Leukemia, Promyelocytic, Acute

acetylcysteine has been researched along with Leukemia, Promyelocytic, Acute in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (21.05)18.2507
2000's11 (57.89)29.6817
2010's3 (15.79)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Hu, XX; Huang, Y; Kang, YH; Ma, YX; Meng, QH; Pan, XB; Wu, J; Wu, T; Wu, XJ; You, YQ; Zhang, N1
Fu, Z; He, B; Jin, Y; Kong, B; Wang, X; Wei, L; Xie, X1
Bharadwaj, AG; Cohen, AM; Holloway, RW; Marcato, P; Marignani, PA; Rahman, M; Thomas, ML; Waisman, DM1
Aljada, A; Aziz, MA; El-Abadelah, MM; Nasr, A; Sabri, SS; Saleh, AM; Zahra, JA1
Li, J; Shen, T; Zhang, ZN; Zuo, L1
Li, J; Shen, T; Xu, CM; Zhang, ZN; Zuo, L1
Fujii, M; Harazoro, K; Hou, DX; Imamura, I; Kubo, M; Lin, S; Ose, T; Terahara, N; Uto, T; Yoshimoto, M1
Aguilar, TM; Bahlis, NJ; Boise, LH; Krett, N; Lee, KP; McCafferty-Grad, J; Reis, I1
Jin, JY; Kim, IS; Lee, IH; Park, SJ1
Fujita, H; Inoue, A; Kanno, T; Muranaka, S; Tamai, H; Utsumi, K1
Bai, H; Chen, J; Kang, J; Wang, C1
Jing, Y; Li, C; Song, D; Wang, R; Zhao, G; Zhao, L1
Bondza-Kibangou, P; El Khoury, V; Millot, C; Millot, JM1
Bessho, R; Hirota, H; Kawai, M; Kubota, M; Kuwakado, K; Lin, YW; Matsubara, K; Nishikomori, R; Okuda, A; Wakazono, Y1
Hachiya, T; Kitamura, K; Miyazaki, T; Naoe, T; Ohno, R; Omura, S; Tanaka, K; Yoshida, H1
Chau, YP; Don, MJ; Kuo, ML; Shiah, SG1
Chai, Y; Koppenhafer, SL; Paulson, HL; Perez, MK; Shoesmith, SJ1
Briehl, MM; Dorr, RT; Dvorakova, K; Payne, CM; Tome, ME; Waltmire, CN1
Chen, YC; Hou, WC; Lee, WR; Lin, HY; Shen, SC; Yang, LL1

Other Studies

19 other study(ies) available for acetylcysteine and Leukemia, Promyelocytic, Acute

ArticleYear
DDX5-targeting fully human monoclonal autoantibody inhibits proliferation and promotes differentiation of acute promyelocytic leukemia cells by increasing ROS production.
    Cell death & disease, 2020, 07-20, Volume: 11, Issue:7

    Topics: Acetylcysteine; Animals; Antibodies, Monoclonal; Cell Cycle Checkpoints; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; DEAD-box RNA Helicases; Down-Regulation; Gene Expression Regulation, Leukemic; Gene Silencing; Humans; Leukemia, Promyelocytic, Acute; Male; Mice, Inbred BALB C; Neutrophils; Reactive Oxygen Species

2020
β-Cypermethrin and its metabolite 3-phenoxybenzoic acid induce cytotoxicity and block granulocytic cell differentiation in HL-60 cells.
    Acta biochimica et biophysica Sinica, 2018, Aug-01, Volume: 50, Issue:8

    Topics: Acetylcysteine; Apoptosis; Benzoates; Cell Differentiation; Cell Survival; Dose-Response Relationship, Drug; Free Radical Scavengers; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Leukemic; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Pyrethrins; Reactive Oxygen Species

2018
Regulation of cell surface protease receptor S100A10 by retinoic acid therapy in acute promyelocytic leukemia (APL)
    Cell death & disease, 2018, 09-11, Volume: 9, Issue:9

    Topics: Acetylcysteine; Animals; Annexin A2; Antineoplastic Agents; Cell Line, Tumor; HEK293 Cells; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; MCF-7 Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; S100 Proteins; Tretinoin; U937 Cells; Ubiquitination

2018
The pyridone-annelated isoindigo (5'-Cl) induces apoptosis, dysregulation of mitochondria and formation of ROS in leukemic HL-60 cells.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2015, Volume: 35, Issue:5

    Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Caspases; Cell Line, Tumor; Cytochromes c; HL-60 Cells; Humans; Indoles; Leukemia, Promyelocytic, Acute; Membrane Potential, Mitochondrial; Mitochondria; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Pyridones; Pyrrolidines; Reactive Oxygen Species; Thiocarbamates

2015
[The comparison between the mechanisms of sodium selenite induced apoptosis and arsenic trioxide induced apoptosis in human acute promyelocytic leukemia cell line NB4 cells].
    Zhongguo shi yan xue ye xue za zhi, 2002, Volume: 10, Issue:3

    Topics: Acetylcysteine; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Division; DNA, Neoplasm; Flow Cytometry; Glutathione; Humans; Intracellular Membranes; Leukemia, Promyelocytic, Acute; Membrane Potentials; Mitochondria; Oxides; Reactive Oxygen Species; Sodium Selenite; Tumor Cells, Cultured

2002
Induction of apoptosis by sodium selenite in human acute promyelocytic leukemia NB4 cells: involvement of oxidative stress and mitochondria.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2003, Volume: 17, Issue:1

    Topics: Acetylcysteine; Acridines; Apoptosis; Cell Division; Cell Survival; DNA Fragmentation; Electrophoresis, Agar Gel; Flow Cytometry; G1 Phase; Glutathione; Glutathione Peroxidase; Humans; Leukemia, Promyelocytic, Acute; Luminescent Measurements; Membrane Potentials; Mitochondria; Oxidative Stress; Reactive Oxygen Species; Sodium Selenite; Superoxide Dismutase; Time Factors; Tumor Cells, Cultured

2003
Anthocyanidins induce apoptosis in human promyelocytic leukemia cells: structure-activity relationship and mechanisms involved.
    International journal of oncology, 2003, Volume: 23, Issue:3

    Topics: Acetylcysteine; Anthocyanins; Antioxidants; Apoptosis; Blotting, Western; Caspase 3; Caspases; DNA Fragmentation; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; HL-60 Cells; Humans; Hydrogen Peroxide; Leukemia, Promyelocytic, Acute; Models, Chemical; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-jun; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction; Structure-Activity Relationship; Time Factors

2003
Arsenic trioxide uses caspase-dependent and caspase-independent death pathways in myeloma cells.
    Molecular cancer therapeutics, 2003, Volume: 2, Issue:11

    Topics: Acetylcysteine; Apoptosis; Arsenic Trioxide; Arsenicals; Caspase Inhibitors; Caspases; Drug Resistance, Neoplasm; Humans; Leukemia, Promyelocytic, Acute; Oxides; Plasma Cells; Superoxides; Tumor Cells, Cultured

2003
Auranofin induces apoptosis and when combined with retinoic acid enhances differentiation of acute promyelocytic leukaemia cells in vitro.
    British journal of pharmacology, 2004, Volume: 142, Issue:4

    Topics: Acetylcysteine; Antigens, Surface; Antirheumatic Agents; Apoptosis; Auranofin; Benzimidazoles; Caspase 3; Caspases; CD11b Antigen; Cell Differentiation; DNA; Drug Therapy, Combination; Fluorescent Dyes; HL-60 Cells; Humans; Korea; Leukemia, Promyelocytic, Acute; Nucleosomes; Reactive Oxygen Species; Signal Transduction; Tretinoin; Tumor Cells, Cultured

2004
Molecular mechanism of diclofenac-induced apoptosis of promyelocytic leukemia: dependency on reactive oxygen species, Akt, Bid, cytochrome and caspase pathway.
    Free radical biology & medicine, 2004, Oct-15, Volume: 37, Issue:8

    Topics: 2-Methoxyestradiol; Acetylcysteine; Amino Acid Chloromethyl Ketones; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Carrier Proteins; Caspases; Chromones; Cyclic AMP; Cyclosporine; Cysteine Proteinase Inhibitors; Cytochromes c; Diclofenac; DNA Fragmentation; DNA, Neoplasm; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Estradiol; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Morpholines; Oligopeptides; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase

2004
Trichostatin A improves the anticancer activity of low concentrations of curcumin in human leukemia cells.
    Die Pharmazie, 2006, Volume: 61, Issue:8

    Topics: Acetylation; Acetylcysteine; Antineoplastic Agents, Phytogenic; Antioxidants; Ascorbic Acid; Cell Line, Tumor; Cell Proliferation; Cell Survival; Curcumin; Drug Synergism; Histones; HL-60 Cells; Humans; Hydroxamic Acids; Indicators and Reagents; L-Lactate Dehydrogenase; Leukemia, Promyelocytic, Acute; Protein Synthesis Inhibitors; Reactive Oxygen Species

2006
Ethacrynic acid butyl-ester induces apoptosis in leukemia cells through a hydrogen peroxide mediated pathway independent of glutathione S-transferase P1-1 inhibition.
    Cancer research, 2007, Aug-15, Volume: 67, Issue:16

    Topics: Acetylcysteine; Apoptosis; Caspases; Catalase; Cell Growth Processes; Ethacrynic Acid; Glutathione S-Transferase pi; HL-60 Cells; Humans; Hydrogen Peroxide; K562 Cells; Leukemia, Erythroblastic, Acute; Leukemia, Promyelocytic, Acute

2007
Antioxidants and doxorubicin supplementation to modulate CD14 expression and oxidative stress induced by vitamin D3 and seocalcitol in HL60 cells.
    Oncology reports, 2007, Volume: 18, Issue:6

    Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Calcitriol; Catalase; Cell Differentiation; Doxorubicin; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Lipopolysaccharide Receptors; Oxidative Stress; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Superoxide Dismutase

2007
Pyrrolidine dithiocarbamate, a potent inhibitor of nuclear factor kappa B (NF-kappa B) activation, prevents apoptosis in human promyelocytic leukemia HL-60 cells and thymocytes.
    Biochemical pharmacology, 1994, Nov-16, Volume: 48, Issue:10

    Topics: Acetylcysteine; Apoptosis; Base Sequence; Cytarabine; Endonucleases; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; NF-kappa B; Oligodeoxyribonucleotides; Phenanthrolines; Pyrrolidines; T-Lymphocytes; Thiocarbamates; Thymus Gland; Tumor Cells, Cultured

1994
Accelerated degradation of PML-retinoic acid receptor alpha (PML-RARA) oncoprotein by all-trans-retinoic acid in acute promyelocytic leukemia: possible role of the proteasome pathway.
    Cancer research, 1996, Jul-01, Volume: 56, Issue:13

    Topics: Acetylcysteine; Animals; Antibodies; Cell Differentiation; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Drug Stability; Humans; Immunoblotting; Leukemia, Promyelocytic, Acute; Neoplasm Proteins; Nuclear Proteins; Oncogene Proteins, Fusion; Promyelocytic Leukemia Protein; Rabbits; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Transcription Factors; Tretinoin; Tumor Cells, Cultured; Tumor Suppressor Proteins

1996
Involvement of hydrogen peroxide in topoisomerase inhibitor beta-lapachone-induced apoptosis and differentiation in human leukemia cells.
    Free radical biology & medicine, 1998, Mar-01, Volume: 24, Issue:4

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Ascorbic Acid; Cell Differentiation; DNA Fragmentation; Drug Resistance; Enzyme Inhibitors; Glutathione; Humans; Hydrogen Peroxide; Leukemia, Promyelocytic, Acute; Monocytes; Naphthoquinones; Proto-Oncogene Proteins c-bcl-2; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Vitamin E

1998
Evidence for proteasome involvement in polyglutamine disease: localization to nuclear inclusions in SCA3/MJD and suppression of polyglutamine aggregation in vitro.
    Human molecular genetics, 1999, Volume: 8, Issue:4

    Topics: Acetylcysteine; Adult; Animals; Ataxin-3; Brain; Brain Chemistry; Cell Line; Cell Nucleus; COS Cells; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; HeLa Cells; Humans; Immunohistochemistry; Inclusion Bodies; Leukemia, Promyelocytic, Acute; Machado-Joseph Disease; Male; Multienzyme Complexes; Mutation; Nerve Tissue Proteins; Nuclear Proteins; Oncogene Proteins; PC12 Cells; Peptides; Proteasome Endopeptidase Complex; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Repressor Proteins

1999
Induction of mitochondrial changes in myeloma cells by imexon.
    Blood, 2001, Jun-01, Volume: 97, Issue:11

    Topics: Acetone; Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; Cytochrome c Group; DNA Damage; DNA, Mitochondrial; Electron Transport Complex II; Flow Cytometry; Hexanones; Humans; Leukemia, Promyelocytic, Acute; Lymphocytes; Membrane Potentials; Microscopy, Electron; Mitochondria; Multienzyme Complexes; Multiple Myeloma; Oxidative Stress; Oxidoreductases; Polymerase Chain Reaction; Reactive Oxygen Species; Succinate Dehydrogenase; Thiophenes; Tumor Cells, Cultured

2001
Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca(2+)-dependent endonuclease.
    Biochemical pharmacology, 2002, Jan-15, Volume: 63, Issue:2

    Topics: Acetylcysteine; Apoptosis; Calcium; Caspase 1; Caspase 3; Caspases; Catalase; Cysteine Proteinase Inhibitors; Endonucleases; Enzyme Activation; Flavanones; Flavonoids; Flavonols; Free Radical Scavengers; HL-60 Cells; Humans; Hydrogen Peroxide; Leukemia, Promyelocytic, Acute; Oligopeptides; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Tumor Cells, Cultured

2002