acetylcysteine has been researched along with Leukemia, Myeloid, Acute in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 9 (64.29) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, C; Han, Y; He, X; Hu, X; Kang, H; Liu, S; Liu, Y; Ma, X; Pan, T; Qi, J; Tang, Y; Wu, D; Yao, Y; Zhang, Z; Zhou, M | 1 |
| Alhuthali, HM; Bradshaw, TD; Kam, TS; Lim, KH; Seedhouse, CH | 1 |
| Chen, YH; Han, W; Huang, XJ; Kong, Y; Song, Y; Tang, FF; Wang, Y; Xu, LP; Yan, CH; Zhang, XH; Zhao, HY | 1 |
| Lam, CF; Lam, YM; Ng, RK; Yeung, HT | 1 |
| Chan, SM; Feng, W; Huang, M; Li, MX; Majeti, R; Mitchell, BS; Thomas, D | 1 |
| Åhsberg, J; Halvarsson, C; Jönsson, JI; Kumar, K; Nordigården, A; Rörby, E; Tang, Y; Wong, WM | 1 |
| Darling, D; Eiliazadeh, AL; Gaymes, TJ; Mohamedali, A; Mufti, GJ | 1 |
| Sun, SY | 1 |
| Avigan, D; Kharbanda, S; Kufe, D; Rosenblatt, J; Stone, R; Wu, Z; Yin, L | 1 |
| Braunagel, D; Dransfeld, CL; Ehninger, G; Kramer, M; Mahlknecht, U; Schaich, M | 1 |
| Adamo, L; Amato, G; Anastasi, G; Buccheri, S; Cavalli, M; Chiarenza, A; Conticello, C; De Maria, R; Di Raimondo, F; Giuffrida, R; Giustolisi, R; Gulisano, M; Lombardo, L; Martinetti, D; Parrinello, N | 1 |
| Corey, SJ; Lowell, CA; Mills, GB; Touw, IP; Xia, L; Zhu, QS | 1 |
| Hu, ZB; Li, M; McCulloch, EA; Minden, MD; Miyamoto, N; Yang, GS | 1 |
| Allouche, M; Bailly, JD; Bordier, C; Come, MG; Duchayne, E; Laurent, G; Mansat, V; Quillet-Mary, A | 1 |
3 trial(s) available for acetylcysteine and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Conditioning therapy with N-acetyl-L-cysteine, decitabine and modified BUCY regimen for myeloid malignancies patients prior to allogeneic hematopoietic stem cell transplantation.
Topics: Acetylcysteine; Behavior Therapy; Busulfan; Decitabine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Myeloproliferative Disorders; Neoplasms; Prospective Studies; Reactive Oxygen Species; Transplantation Conditioning | 2023 |
N-acetyl-L-cysteine improves mesenchymal stem cell function in prolonged isolated thrombocytopenia post-allotransplant.
Topics: Acetylcysteine; Bone Marrow Cells; Case-Control Studies; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Mesenchymal Stem Cells; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Thrombocytopenia | 2018 |
The T_T genotype within the NME1 promoter single nucleotide polymorphism -835 C/T is associated with an increased risk of cytarabine induced neurotoxicity in patients with acute myeloid leukemia.
Topics: Acetylcysteine; Adolescent; Adult; Aged; Apoptosis; Cytarabine; Female; Genotype; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neurons; Neurotoxicity Syndromes; NM23 Nucleoside Diphosphate Kinases; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Retrospective Studies; Survival Rate; Young Adult | 2012 |
11 other study(ies) available for acetylcysteine and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
The natural alkaloid Jerantinine B has activity in acute myeloid leukemia cells through a mechanism involving c-Jun.
Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Damage; Drug Screening Assays, Antitumor; Free Radical Scavengers; Humans; Indole Alkaloids; Leukemia, Myeloid, Acute; MAP Kinase Signaling System; Proto-Oncogene Proteins c-jun; Reactive Oxygen Species | 2020 |
Reactive oxygen species activate differentiation gene transcription of acute myeloid leukemia cells via the JNK/c-JUN signaling pathway.
Topics: Acetylcysteine; Cell Differentiation; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; Leukemia, Myeloid, Acute; MAP Kinase Signaling System; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-jun; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Transcription, Genetic | 2018 |
Role of cysteine 288 in nucleophosmin cytoplasmic mutations: sensitization to toxicity induced by arsenic trioxide and bortezomib.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Boronic Acids; Bortezomib; Cell Nucleolus; Cell Proliferation; Cysteine; Cytosol; Drug Resistance, Neoplasm; Flow Cytometry; Free Radical Scavengers; Humans; Leukemia, Myeloid, Acute; Mutation; Nuclear Proteins; Nucleophosmin; Oxides; Pyrazines; Reactive Oxygen Species; Tryptophan; Tumor Cells, Cultured | 2013 |
Coexpression of hyperactivated AKT1 with additional genes activated in leukemia drives hematopoietic progenitor cells to cell cycle block and apoptosis.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Cell Cycle; Cell Division; Cell Movement; Enzyme Activation; fms-Like Tyrosine Kinase 3; Gene Expression Regulation, Leukemic; Genes, bcl-2; Hematopoietic Stem Cells; Leukemia, Myeloid, Acute; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myristic Acid; Neoplasm Proteins; Neoplastic Stem Cells; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; STAT5 Transcription Factor | 2015 |
FLT3 and JAK2 Mutations in Acute Myeloid Leukemia Promote Interchromosomal Homologous Recombination and the Potential for Copy Neutral Loss of Heterozygosity.
Topics: Acetylcysteine; Adolescent; Adult; Aged; Aged, 80 and over; Cell Line, Tumor; Child; fms-Like Tyrosine Kinase 3; Homologous Recombination; Humans; Janus Kinase 2; Leukemia, Myeloid, Acute; Loss of Heterozygosity; Middle Aged; Mutation; Rad51 Recombinase; Reactive Oxygen Species; Sister Chromatid Exchange | 2017 |
N-acetylcysteine, reactive oxygen species and beyond.
Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Line, Tumor; Down-Regulation; Gene Expression Regulation, Leukemic; Glutathione; Glycyrrhetinic Acid; Humans; Leukemia, Myeloid, Acute; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Oxidation-Reduction; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Sulfhydryl Compounds; X-Linked Inhibitor of Apoptosis Protein | 2010 |
MUC1-C oncoprotein suppresses reactive oxygen species-induced terminal differentiation of acute myelogenous leukemia cells.
Topics: Acetylcysteine; Amino Acid Sequence; Apoptosis; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; Leukemia, Myeloid, Acute; Mucin-1; Necrosis; Oligopeptides; Oxidation-Reduction; Oxidative Stress; Phenotype; Protein Structure, Tertiary; Reactive Oxygen Species | 2011 |
Disulfiram, an old drug with new potential therapeutic uses for human hematological malignancies.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Caspases; Cell Line, Tumor; Copper; Disulfiram; Enzyme Inhibitors; Free Radical Scavengers; Humans; Leukemia, Myeloid, Acute; Membrane Potentials; Mitochondrial Membranes; Multiple Myeloma; Oxidative Stress; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reactive Oxygen Species | 2012 |
G-CSF induced reactive oxygen species involves Lyn-PI3-kinase-Akt and contributes to myeloid cell growth.
Topics: Acetylcysteine; Animals; Bone Marrow Cells; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Mice; Mice, Knockout; NADPH Oxidases; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Protein Transport; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Receptors, Granulocyte Colony-Stimulating Factor; Sequence Deletion; Signal Transduction; src-Family Kinases | 2006 |
Mechanism of cytosine arabinoside toxicity to the blast cells of acute myeloblastic leukemia: involvement of free radicals.
Topics: Acetylcysteine; Antioxidants; Base Sequence; Blotting, Northern; Cytarabine; Down-Regulation; Drug Interactions; Drug Screening Assays, Antitumor; Free Radicals; Gene Expression Regulation, Leukemic; Humans; Hydrocortisone; Hydrogen Peroxide; Leukemia, Myeloid, Acute; Lymphocyte Activation; Lymphocytes; Molecular Sequence Data; Polymerase Chain Reaction; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured | 1995 |
Daunorubicin-induced internucleosomal DNA fragmentation in acute myeloid cell lines.
Topics: Acetylcysteine; Antibiotics, Antineoplastic; Antioxidants; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Buthionine Sulfoximine; Cell Differentiation; Daunorubicin; DNA Damage; DNA Nucleotidylexotransferase; DNA, Neoplasm; Free Radical Scavengers; Humans; Leukemia, Myeloid, Acute; Methionine Sulfoximine; Nucleosomes; Pyrrolidines; Thiocarbamates; Tumor Cells, Cultured; Verapamil | 1996 |