Compounds > acetylcysteine

acetylcysteine and Ischemia

acetylcysteine has been researched along with Ischemia in 78 studies

Research

Studies (78)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's20 (25.64)18.2507
2000's30 (38.46)29.6817
2010's19 (24.36)24.3611
2020's9 (11.54)2.80

Authors

AuthorsStudies
Cowan, PJ; Cui, Y; Fichman, Y; Hao, H; He, X; Hill, MA; Liu, Z; Mittler, R; Wang, M; Xu, H; Yang, C; Zhang, G; Zhou, S; Zhu, Q1
Cashin, J; Desai, K; DeSilva, G; Engel, C; Lee, JV; Semenkovich, CF; Tay, S; Zayed, MA1
Costa, RIDD; Fischer, JMDS; Koike, MK; Montero, EFS; Rasslan, R; Utiyama, EM1
Apaijai, N; Arunsak, B; Chattipakorn, N; Chattipakorn, SC; Chunchai, T; Liang, G; Maneechote, C; Pintana, H; Singhanat, K; Vongsfak, J; Wu, D1
Abraham-Fan, RJ; Lindner, JR; López, JA; Muller, M; Ozawa, K; Packwood, W; Varlamov, O; Wu, MD; Xie, A1
Gupta, JK; Kumar, S; Mukherjee, S; Patel, A; Singh, K1
Goksoy, E; Kepil, N; Umman, V; Uzun, H1
Chakfé, N; Charles, AL; Delay, C; Geny, B; Georg, I; Goupilleau, F; Lejay, A; Talha, S; Thaveau, F1
Cui, Y; Hao, H; He, X; Li, X; Liu, L; Liu, Z; Sen, CK; Tian, J; Xiao, Y; Xie, X; Zhang, J1
Brandão, JCM; Camargo, CR; Leite, AA; Marinho, M; Oliveira-Junior, IS; Reiter, RJ; Sakae, TM1
Constantino, L; da Silva, LA; Dal-Pizzol, F; Dall'Igna, DM; de Medeiros, WA; Dos Santos Cardoso, J; Manfredini, A; Michels, M; Ritter, C; Scaini, G; Streck, EL; Vuolo, F1
Archer, DR; Hansen, L; Joseph, G; Lyle, AN; Okwan-Duodu, D; Taylor, WR; Weiss, D1
McClain, SA; Singer, AJ; Towery, H1
Chakfe, N; Charles, AL; Enache, I; Geny, B; Lambert, A; Lejay, A; Paradis, S; Talha, S; Thaveau, F1
Furukawa, LNS; Pereira, RC; Romão, CM; Shimizu, MHM1
Ambros, VR; Curry, SC; Jaeschke, H; Kanchagar, C; Lee, RC; McGill, MR; Veksler-Lublinsky, I; Ward, J1
Chang, Y; Huang, CC; Hwang, SM; Lin, KJ; Pan, WY; Sung, HW; Tsai, HW; Tseng, MT; Wei, HJ; Yang, YP1
Deng, Y; Lu, X; Zhao, L1
Chen, Y; Gao, F; Lu, B; Shi, G; Wang, B; Zhang, Y; Zheng, F; Zhong, S1
Bennett, MV; Court-Vazquez, B; Gertner, M; Hwang, JY; Ofengeim, D; Pontarelli, F; Zukin, RS1
Bae, YC; Jung, JS; Kim, DH; Kim, HK; Kim, JT; Kim, YJ; Kim, YK; Kwon, CH1
DI, JF; Feng, Z; Lin, Y; Zeng, S1
Borghese, F; Pisarri, S; Rosato, E; Salsano, F1
Abdelsaid, MA; Al-Shabrawey, M; El-Remessy, AB; Matragoon, S; Pillai, BA; Prakash, R1
Jo, YH; Kim, K; Kim, TY; Kwon, WY; Lee, CC; Lee, JH; Rhee, JE; Singer, AJ; Suh, GJ1
Barbosa, PR; Cardoso, MR; Dal-Pizzol, F; Daufenbach, JF; Gonçalves, CL; Machado, RA; Rezin, GT; Roza, CA; Scaini, G; Schuck, PF; Streck, EL1
Ichihara, G; Ichihara, S; Itoh, K; Liu, F; Murohara, T; Yamada, Y; Yamamoto, M1
Moldobaeva, A; Nijmeh, J; Wagner, EM1
Bächle, AC; Harder, Y; Menger, MD; Mörsdorf, P; Ong, MF; Rezaeian, F1
Kubota, Y; Nakamura-Ishizu, A; Okuno, Y; Otsu, K; Suda, T1
Jahanshahi, A; Jahanshahi, G; Khansari, M; Sotoudeh, A; Takhtfooladi, HA; Takhtfooladi, MA1
Giri, S; Mehta, A; Orak, JK; Sekhon, CP; Singh, AK1
Lepor, NE1
Arbak, S; Ayanoğlu-Dülger, G; Ersoy, Y; Kaçmaz, A; Sehirli, AO; Sener, G; Tosun, O1
Bals, R; Boekstegers, P; Clauss, M; Gallo, RL; Gloe, T; Hiemstra, PS; Issbrücker, K; Karl, A; Koczulla, R; Krötz, F; Kupatt, C; Lebherz, C; Pfosser, A; Raake, P; Unterberger, P; Vogelmeier, C; von Degenfeld, G; Welsch, U; Zahler, S; Zaiou, M1
Andersson, R; Börjesson, A; Olanders, K; Sun, ZW1
Brokering, KL; Theobald, JC; Walker, PD1
Durham, JH; Fishbane, S; Marzo, K; Rudnick, M1
Bohosiewicz, J; Byrka-Owczarek, K; Koszutski, T; Krasoń, M; Steplewska-Mazur, K; Wojtynek, G1
Aydogdu, N; Erbas, H; Kaymak, K1
Arregui, B; Carbonell, LF; Fenoy, FJ; González-Mora, JL; Ruiz, F; Salom, MG1
Andrade, L; Coimbra, TM; de Araujo, M; Rodrigues, AC; Seguro, AC1
Badak, MI; Boga, M; Dikicioglu, E; Discigil, B; Gurcun, U; Meteoglu, I; Ozkisacik, EA; Yenisey, C1
Chen, CF; Chen, HI; Leu, FJ; Wang, D1
Abdulkader, R; Castro, I; Macedo, E; Sobrinho, AC; Vieira, JM; Yu, L1
Weinbroum, AA1
Inomata, M; Nakamura, M; Ohno, H; Shintani-Ishida, K; Uemura, K; Yoshida, K1
Assy, N; Gefen, H; Hussein, O; Schlesinger, S1
Kimura, T; Kita, M; Suzuma, K; Takagi, H; Watanabe, D; Yoshimura, N1
Geudens, N; Lerut, TE; Neyrinck, AP; Rega, FR; Van Raemdonck, DE; Vanaudenaerde, BM; Verleden, GM; Wuyts, WA1
Caputo, FJ; Deitch, EA; Qin, X; Xu, DZ1
Burigo, M; Constantino, L; Dal-Pizzol, F; Di-Pietro, PB; Dias, ML; Machado, RA; Scaini, G; Streck, EL1
Chang, Q; Cox, RA; Gong, X; Gould, LJ; Zhang, Q1
Itoh, M; Joh, T; Seno, K; Yokoyama, Y1
Acarli, K; Emre, S; Fukuzawa, K; Miller, CM; Schwartz, ME; Senyuz, O1
Davenport, M; Dunne, JB; Tredger, JM; Williams, R1
Miller, CM; Schwartz, ME; Stump, DD; Theise, ND; Vivot, C1
Gebhard, MM; Gehrcke, R; Herfarth, C; Koeppel, TA; Lehmann, TG; Otto, G; Post, S; Thies, JC1
Fukuse, T; Hirata, T; Hitomi, S; Inui, K; Kosaka, S; Liu, CJ; Ueda, M; Wada, H; Yokomise, H1
Davis, R; DiMari, J; Megyesi, J; Price, P; Safirstein, R; Udvarhelyi, N1
Baek, Y; Barama, A; Boudjema, K; Jaeck, D; Kitamura, N; Kumada, K; Nagasaki, H; Nakano, H; Suzuki, T; Tatsuno, M; Yamaguchi, M1
Carbonell, LF; Cartagena, J; Fenoy, FJ; López Conesa, E; Parrilla, P; Quesada, T; Ramírez, P; Salom, MG1
Azzimonti, B; Bernelli-Zazzera, A; Cairo, G; Minotti, G; Recalcati, S; Tacchini, L1
Demir, S; Inal-Erden, M1
Ariceta, J; Ferrer, JV; Gomis, T; Guerrero, D; Herrera, J; Larrea, MM; Lera, JM1
Ariceta, J; Balén, E; Ferrer, JV; Gomis, T; Guerrero, D; Larrea, MM; Lera, JM1
Fujiwara, Y; Kigawa, G; Kitamura, N; Kumada, K; Kuzume, M; Nagasaki, H; Nakano, H; Sasaki, J; Shimura, H; Takeuchi, S; Yamaguchi, M; Yoshida, K1
Chavez-Cartaya, R; Jamieson, NV; Marin, J; Pino-Chavez, G; Ramirez, P2
Hur, GM; Jeon, BH; Kim, YM; Lee, JH; Ryu, YS; Seok, JH; Yun, HY1
Ariceta, J; Balén, E; Ferrer, JV; Guerrero, D; Herrera, J; Lera, JM1
Defraigne, JO; Detry, O; Franssen, C; Limet, R; Meurisse, M; Pincemail, J1
Ben-Abraham, R; Karchevski, E; Rudick, V; Weinbroum, AA1
Kötting, M; Minor, T1
Itoh, M; Matsumura, Y; Ohkita, M; Shibata, A; Takaoka, M1
Entman, ML; Evans, AJ; Frangogiannis, NG; Lakshminarayanan, V; Lewallen, M; Michael, LH; Wedin, KE1
Eadie, PA; Knight, KR; Kuwata, N; Lepore, DA; MacPhadyen, K; O'Brien, BM1
Grotyohann, LW; Martin, LF; Scaduto, RC; Slusser, SO1

Reviews

3 review(s) available for acetylcysteine and Ischemia

ArticleYear
A review of contemporary prevention strategies for radiocontrast nephropathy: a focus on fenoldopam and N-acetylcysteine.
    Reviews in cardiovascular medicine, 2003, Volume: 4 Suppl 1

    Topics: Acetylcysteine; Animals; Contrast Media; Diabetes Complications; Dogs; Dopamine Agonists; Evaluation Studies as Topic; Fenoldopam; Fluid Therapy; Free Radical Scavengers; Humans; Ischemia; Kidney Diseases; Kidney Tubules; Models, Animal

2003
Fenoldopam and N-acetylcysteine for the prevention of radiographic contrast material-induced nephropathy: a review.
    Pharmacotherapy, 2003, Volume: 23, Issue:12

    Topics: Acetylcysteine; Contrast Media; Dopamine Agonists; Fenoldopam; Free Radical Scavengers; Humans; Ischemia; Kidney; Kidney Diseases; Randomized Controlled Trials as Topic

2003
N-acetylcysteine in the prevention of radiocontrast-induced nephropathy.
    Journal of the American Society of Nephrology : JASN, 2004, Volume: 15, Issue:2

    Topics: Acetylcysteine; Clinical Trials as Topic; Contrast Media; Humans; Ischemia; Kidney; Kidney Diseases; Kidney Tubules; Radiography

2004

Trials

2 trial(s) available for acetylcysteine and Ischemia

ArticleYear
Impact of N-Acetyl-Cysteine on Ischemic Stumps Following Major Lower Extremity Amputation: A Pilot Randomized Clinical Trial.
    Annals of surgery, 2022, 11-01, Volume: 276, Issue:5

    Topics: Acetylcysteine; Amputation Stumps; Amputation, Surgical; Humans; Ischemia; Lower Extremity; Peripheral Arterial Disease; Pilot Projects; Risk Factors; Treatment Outcome

2022
Lack of protection of N-acetylcysteine (NAC) in acute renal failure related to elective aortic aneurysm repair-a randomized controlled trial.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:7

    Topics: Acetylcysteine; Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Aortic Aneurysm; Double-Blind Method; Female; Free Radical Scavengers; Humans; Ischemia; Male; Middle Aged; Placebos; Treatment Outcome

2006

Other Studies

73 other study(ies) available for acetylcysteine and Ischemia

ArticleYear
Combination of Antioxidant Enzyme Overexpression and N-Acetylcysteine Treatment Enhances the Survival of Bone Marrow Mesenchymal Stromal Cells in Ischemic Limb in Mice With Type 2 Diabetes.
    Journal of the American Heart Association, 2021, 10-05, Volume: 10, Issue:19

    Topics: Acetylcysteine; Animals; Antioxidants; Bone Marrow; Bone Marrow Cells; Chronic Limb-Threatening Ischemia; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glutathione Peroxidase; Ischemia; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Reactive Oxygen Species; Superoxide Dismutase

2021
Effects of N-acetylcysteine on the inflammatory response and bacterial translocation in a model of intestinal obstruction and ischemia in rats.
    Acta cirurgica brasileira, 2023, Volume: 37, Issue:12

    Topics: Acetylcysteine; Animals; Bacterial Translocation; Inflammation; Interleukin-10; Interleukin-6; Intestinal Obstruction; Ischemia; Rats; Rats, Wistar; Resuscitation; Saline Solution, Hypertonic; Shock, Hemorrhagic; Tumor Necrosis Factor-alpha

2023
Acute administration of myeloid differentiation factor 2 inhibitor and N-acetyl cysteine attenuate brain damage in rats with cardiac ischemia/reperfusion injury.
    Archives of biochemistry and biophysics, 2023, 05-15, Volume: 740

    Topics: Acetylcysteine; Animals; Brain; Encephalitis; Ischemia; Male; Myocardial Reperfusion Injury; Oxidative Stress; Rats; Reperfusion Injury

2023
Elevated LDL Cholesterol Increases Microvascular Endothelial VWF and Thromboinflammation After Myocardial Infarction.
    Arteriosclerosis, thrombosis, and vascular biology, 2023, Volume: 43, Issue:6

    Topics: Acetylcysteine; ADAMTS13 Protein; Animals; Cholesterol, LDL; Inflammation; Ischemia; Mice; Myocardial Infarction; Thromboinflammation; von Willebrand Factor

2023
Hepatic Ischemia-reperfusion Injury: Protective Approaches and Treatment.
    Current molecular pharmacology, 2024, Volume: 17

    Topics: Acetylcysteine; Antioxidants; Humans; Ischemia; Liver; Reactive Oxygen Species; Reperfusion Injury

2024
Pre-treatment with pregabalin reduces liver ischemia-reperfusion injury in rats: tissue protection with an analgesic.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:21

    Topics: Acetylcysteine; Alanine Transaminase; Analgesics; Animals; Aspartate Aminotransferases; Ischemia; Liver; Male; Pregabalin; Rats; Rats, Wistar; Reperfusion Injury; Tumor Necrosis Factor-alpha

2023
Critical Limb Ischaemia Exacerbates Mitochondrial Dysfunction in ApoE-/- Mice Compared with ApoE+/+ Mice, but N-acetyl Cysteine still Confers Protection.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2019, Volume: 58, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Calcium; Critical Illness; Disease Models, Animal; Hyperlipidemias; Ischemia; Mice, Knockout, ApoE; Mitochondria, Muscle; Muscle, Skeletal; Oxidative Stress; Peripheral Arterial Disease; Reactive Oxygen Species

2019
N-acetylcysteine differentially regulates the populations of bone marrow and circulating endothelial progenitor cells in mice with limb ischemia.
    European journal of pharmacology, 2020, Aug-15, Volume: 881

    Topics: Acetylcysteine; Angiogenesis Inducing Agents; Animals; Antioxidants; Apoptosis; Bone Marrow Cells; Cell Proliferation; Disease Models, Animal; Endothelial Progenitor Cells; Hindlimb; Ischemia; Male; Mice, Inbred C57BL; Muscle, Skeletal; Neovascularization, Physiologic; Oxidative Stress; Phenotype; Reactive Oxygen Species; Recovery of Function

2020
Melatonin can be, more effective than N-acetylcysteine, protecting acute lung injury induced by intestinal ischemia-reperfusion in rat model.
    Clinics (Sao Paulo, Brazil), 2021, Volume: 76

    Topics: Acetylcysteine; Acute Lung Injury; Animals; Ischemia; Melatonin; Rats; Rats, Wistar; Reperfusion; Reperfusion Injury

2021
N-acetylcysteine effects on a murine model of chronic critical limb ischemia.
    Biochimica et biophysica acta. Molecular basis of disease, 2018, Volume: 1864, Issue:2

    Topics: Acetylcysteine; Animals; Disease Models, Animal; Hindlimb; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Interleukin-6; Ischemia; Lactic Acid; Male; Muscle, Skeletal; Nitrates; Nitrites; Oxidative Stress; Oxygen; Oxygen Consumption; Peroxidase; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Vascular Endothelial Growth Factor A

2018
Impaired Collateral Vessel Formation in Sickle Cell Disease.
    Arteriosclerosis, thrombosis, and vascular biology, 2018, Volume: 38, Issue:5

    Topics: Acetylcysteine; Anemia, Sickle Cell; Animals; Antioxidants; Blood Flow Velocity; Collateral Circulation; Disease Models, Animal; Female; Genetic Predisposition to Disease; Hindlimb; Hydrogen Peroxide; Ischemia; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Skeletal; Neovascularization, Physiologic; Neutrophils; Oxidative Stress; Phenotype; Regional Blood Flow; Time Factors

2018
Effect of tadalafil on reduction of necrosis in the ischemic zone in a rat comb burn model.
    Burns : journal of the International Society for Burn Injuries, 2018, Volume: 44, Issue:6

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Burns; Disease Models, Animal; Disease Progression; Free Radical Scavengers; Ischemia; Naproxen; Necrosis; Random Allocation; Rats; Rats, Sprague-Dawley; Skin; Tadalafil; Vasodilator Agents

2018
N-Acetyl Cysteine Restores Limb Function, Improves Mitochondrial Respiration, and Reduces Oxidative Stress in a Murine Model of Critical Limb Ischaemia.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2018, Volume: 56, Issue:5

    Topics: Acetylcysteine; Animals; Calcium; Ischemia; Male; Mice; Mitochondria; Muscle, Skeletal; Oxidative Stress; Reactive Oxygen Species

2018
N-acetyl-l-cysteine exacerbates kidney dysfunction caused by a chronic high-sodium diet in renal ischemia and reperfusion rats.
    Life sciences, 2019, Aug-15, Volume: 231

    Topics: Acetylcysteine; Acute Kidney Injury; Animals; Blood Pressure; Brain Ischemia; Free Radical Scavengers; Ischemia; Kidney; Male; Rats; Rats, Wistar; Reperfusion; Reperfusion Injury; Sodium Chloride, Dietary

2019
Circulating microRNA profiles in human patients with acetaminophen hepatotoxicity or ischemic hepatitis.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Aug-19, Volume: 111, Issue:33

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Hepatitis; Humans; Ischemia; MicroRNAs; Poisoning; Real-Time Polymerase Chain Reaction

2014
Enhancement of cell adhesion, retention, and survival of HUVEC/cbMSC aggregates that are transplanted in ischemic tissues by concurrent delivery of an antioxidant for therapeutic angiogenesis.
    Biomaterials, 2016, Volume: 74

    Topics: Acetylcysteine; Animals; Antioxidants; Cell Adhesion; Cell Survival; Cell Transplantation; Human Umbilical Vein Endothelial Cells; Humans; Ischemia; Male; Mesenchymal Stem Cells; Mice; Mice, Inbred BALB C; Neovascularization, Physiologic; Oxidative Stress; Reactive Oxygen Species

2016
A multidrug cocktail approach attenuates ischemic-type biliary lesions in liver transplantation from non-heart-beating donors.
    Medical hypotheses, 2016, Volume: 91

    Topics: Acetylcysteine; Animals; Biliary Tract Diseases; Drug Therapy, Combination; Epithelial Cells; Epoprostenol; Female; Hemin; Hepatocytes; Humans; Inflammation; Ischemia; Kupffer Cells; Liver; Liver Failure; Liver Transplantation; Models, Theoretical; Organ Preservation; Reactive Oxygen Species; Reoperation; Reperfusion Injury; Streptokinase; Swine; Taurochenodeoxycholic Acid; Thiazolidinediones; Tissue Donors; Warm Ischemia

2016
N-n-butyl haloperidol iodide ameliorates hypoxia/reoxygenation injury through modulating the LKB1/AMPK/ROS pathway in cardiac microvascular endothelial cells.
    Oncotarget, 2016, Jun-07, Volume: 7, Issue:23

    Topics: Acetylcysteine; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Apoptosis; Cell Hypoxia; Cell Survival; Endothelial Cells; Haloperidol; Ischemia; L-Lactate Dehydrogenase; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2016
Global ischemia induces lysosomal-mediated degradation of mTOR and activation of autophagy in hippocampal neurons destined to die.
    Cell death and differentiation, 2017, Volume: 24, Issue:2

    Topics: Acetylcysteine; Adenine; AMP-Activated Protein Kinases; Animals; Autophagy; Autophagy-Related Protein-1 Homolog; Beclin-1; Cells, Cultured; Hippocampus; Ischemia; Leupeptins; Lysosomes; Male; Microtubule-Associated Proteins; Neurons; Phosphorylation; Rats; RNA Interference; Sirolimus; TOR Serine-Threonine Kinases

2017
Alterations in the proangiogenic functions of adipose tissue-derived stromal cells isolated from diabetic rats.
    Stem cells and development, 2008, Volume: 17, Issue:4

    Topics: Acetylcysteine; Adipose Tissue; Animals; Catalase; Cell Proliferation; Diabetes Mellitus, Experimental; Free Radical Scavengers; Glucose; Hindlimb; Humans; Ischemia; Male; Mice; Mice, Nude; Neovascularization, Physiologic; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Stromal Cells; Time Factors

2008
[Protective effects and mechanism of N-acetylcysteine on cardiac injury induced by ischemia/reperfusion in diabetic rats].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2009, Volume: 25, Issue:8

    Topics: Acetylcysteine; Animals; Diabetes Complications; Disease Models, Animal; Female; Humans; Ischemia; Male; Myocardial Reperfusion Injury; Myocytes, Cardiac; Random Allocation; Rats; Rats, Sprague-Dawley

2009
The treatment with N-acetylcysteine of Raynaud's phenomenon and ischemic ulcers therapy in sclerodermic patients: a prospective observational study of 50 patients.
    Clinical rheumatology, 2009, Volume: 28, Issue:12

    Topics: Acetylcysteine; Female; Fingers; Free Radical Scavengers; Humans; Infusions, Intravenous; Ischemia; Male; Middle Aged; Raynaud Disease; Scleroderma, Systemic; Skin; Skin Ulcer; Treatment Outcome

2009
Early intervention of tyrosine nitration prevents vaso-obliteration and neovascularization in ischemic retinopathy.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 332, Issue:1

    Topics: Acetylcysteine; Animals; Animals, Newborn; Apoptosis; Blotting, Western; Catechin; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Glutathione; Hyperoxia; Hypoxia; Ischemia; Lipid Peroxidation; Metalloporphyrins; Mice; Mice, Inbred C57BL; Peroxynitrous Acid; Protective Agents; Retinal Neovascularization; Retinal Vessels; Tyrosine

2010
Effect of speed of rewarming and administration of anti-inflammatory or anti-oxidant agents on acute lung injury in an intestinal ischemia model treated with therapeutic hypothermia.
    Resuscitation, 2010, Volume: 81, Issue:1

    Topics: Acetylcysteine; Acute Lung Injury; Animals; Dexamethasone; Disease Models, Animal; Hypothermia, Induced; Intestines; Ischemia; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Rewarming; Survival Rate; Time Factors

2010
Inhibition of mitochondrial respiratory chain in the brain of rats after renal ischemia is prevented by N-acetylcysteine and deferoxamine.
    Metabolic brain disease, 2010, Volume: 25, Issue:2

    Topics: Acetylcysteine; Animals; Cell Respiration; Deferoxamine; Disease Models, Animal; Drug Combinations; Drug Synergism; Electron Transport; Electron Transport Complex I; Free Radical Scavengers; Ischemia; Kidney Diseases; Male; Rats; Rats, Wistar

2010
Ablation of the transcription factor Nrf2 promotes ischemia-induced neovascularization by enhancing the inflammatory response.
    Arteriosclerosis, thrombosis, and vascular biology, 2010, Volume: 30, Issue:8

    Topics: Acetylcysteine; Angiogenic Proteins; Animals; Antioxidants; Capillaries; Cell Adhesion Molecules; Chemokine CCL2; Cyclooxygenase 2; Disease Models, Animal; Endothelial Cells; Femoral Artery; Glutathione; Heme Oxygenase-1; Hindlimb; Inflammation; Inflammation Mediators; Ischemia; Laser-Doppler Flowmetry; Ligation; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Skeletal; Neovascularization, Physiologic; NF-E2-Related Factor 2; Oxidative Stress; Peroxiredoxins; Regional Blood Flow; RNA, Messenger; Superoxides; Thioredoxins; Time Factors; Tumor Necrosis Factor-alpha

2010
Role of ROS in ischemia-induced lung angiogenesis.
    American journal of physiology. Lung cellular and molecular physiology, 2010, Volume: 299, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Disease Models, Animal; Glutathione; Glutathione Disulfide; Ischemia; Lung; Male; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; NF-E2-Related Factor 2; Pulmonary Artery; Reactive Oxygen Species

2010
N-acetylcysteine attenuates leukocytic inflammation and microvascular perfusion failure in critically ischemic random pattern flaps.
    Microvascular research, 2011, Volume: 82, Issue:1

    Topics: Acetylcysteine; Animals; Apoptosis; Arterioles; Capillaries; Cell Adhesion; Dermatologic Surgical Procedures; Inflammation; Ischemia; Leukocyte Rolling; Leukocytes; Mice; Mice, Inbred C57BL; Microcirculation; Microvessels; Necrosis; Regional Blood Flow; Surgical Flaps; Vasodilation

2011
Pathological neoangiogenesis depends on oxidative stress regulation by ATM.
    Nature medicine, 2012, Volume: 18, Issue:8

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cells, Cultured; DNA Repair; DNA-Binding Proteins; Endothelium, Vascular; Enzyme Activation; Eye Proteins; Female; Humans; Hydrogen Peroxide; Ischemia; Lipid Peroxidation; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Neovascularization, Pathologic; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Pyrones; Reactive Oxygen Species; Retinal Neovascularization; Retinal Vessels; Signal Transduction; Tumor Suppressor Proteins; Vascular Endothelial Growth Factor A

2012
Protective effect of N-acetylcysteine on kidney as a remote organ after skeletal muscle ischemia-reperfusion.
    Acta cirurgica brasileira, 2012, Volume: 27, Issue:9

    Topics: Acetylcysteine; Acute Kidney Injury; Animals; Creatinine; Ischemia; Male; Muscle, Skeletal; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury

2012
Attenuation of ischemia/reperfusion induced MAP kinases by N-acetyl cysteine, sodium nitroprusside and phosphoramidon.
    Molecular and cellular biochemistry, 2002, Volume: 240, Issue:1-2

    Topics: Acetylcysteine; Animals; Disease Models, Animal; Glycopeptides; Immunohistochemistry; Ischemia; Ischemic Preconditioning; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinases; Nitroprusside; Phosphorylation; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Reperfusion; Reperfusion Injury; Survival Rate; Time Factors; Transcription Factor AP-1

2002
Melatonin and N-acetylcysteine have beneficial effects during hepatic ischemia and reperfusion.
    Life sciences, 2003, May-02, Volume: 72, Issue:24

    Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Female; Free Radical Scavengers; Glutathione; Ischemia; Lipid Peroxidation; Liver; Liver Circulation; Liver Function Tests; Male; Malondialdehyde; Melatonin; Neutrophil Infiltration; Oxidation-Reduction; Peroxidase; Proteins; Rats; Rats, Wistar; Reperfusion Injury

2003
An angiogenic role for the human peptide antibiotic LL-37/hCAP-18.
    The Journal of clinical investigation, 2003, Volume: 111, Issue:11

    Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Apoptosis; Blotting, Western; Calcium; Cathelicidins; Cell Division; Cells, Cultured; Collagen; Cricetinae; Drug Combinations; Endothelium, Vascular; Enzyme Inhibitors; Humans; Indoles; Inflammation; Ischemia; Laminin; Maleimides; Mesocricetus; Mice; Neovascularization, Physiologic; NF-kappa B; Peptides; Prodrugs; Proteoglycans; Rabbits; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Lipoxin; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Wound Healing

2003
Protective effects of N-acetyl-L-cysteine and platelet activating factor inhibition are not linked to intercellular adhesion molecule-1 expression after intestinal ischemia and reperfusion injury in rats.
    Scandinavian journal of gastroenterology, 2003, Volume: 38, Issue:6

    Topics: Acetylcysteine; Animals; Cytoprotection; Free Radical Scavengers; Imidazoles; Intercellular Adhesion Molecule-1; Interleukin-1; Intestinal Mucosa; Intestines; Ischemia; Leucine; Male; Neutrophil Infiltration; Permeability; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2003
The evaluation of the protective action of antioxidants on small intestine of rabbits experimentally injured by ischemia and reperfusion.
    Journal of pediatric surgery, 2004, Volume: 39, Issue:8

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Edema; Hemorrhage; Intestinal Mucosa; Intestine, Small; Ischemia; Ligation; Male; Mannitol; Mesenteric Artery, Superior; Oxidative Stress; Rabbits; Reperfusion Injury

2004
Effects of N-acetylcysteine on arginase, ornithine and nitric oxide in renal ischemia-reperfusion injury.
    Pharmacological research, 2004, Volume: 50, Issue:5

    Topics: Acetylcysteine; Animals; Arginase; Enzyme Activation; Female; Ischemia; Kidney; Nitric Oxide; Ornithine; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2004
Renal ischemia induces an increase in nitric oxide levels from tissue stores.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2005, Volume: 289, Issue:5

    Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Enzyme Inhibitors; Ischemia; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley

2005
Magnesium supplementation combined with N-acetylcysteine protects against postischemic acute renal failure.
    Journal of the American Society of Nephrology : JASN, 2005, Volume: 16, Issue:11

    Topics: Acetylcysteine; Acute Kidney Injury; Animals; Blood Flow Velocity; Cell Membrane; Dietary Supplements; Disease Models, Animal; Glomerular Filtration Rate; Ischemia; Kidney; Magnesium Chloride; Male; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Renal Circulation

2005
The combined effect of iloprost and N-acetylcysteine in preventing spinal cord ischemia in rabbits.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2006, Volume: 31, Issue:4

    Topics: Acetylcysteine; Animals; Cytoprotection; Iloprost; Ischemia; Male; Models, Animal; Nitric Oxide; Paraplegia; Phosphopyruvate Hydratase; Rabbits; Random Allocation; Spinal Cord; Vasodilator Agents

2006
Oxygen radicals and matrix metalloproteinases mediate reperfusion liver injury.
    Transplantation proceedings, 2005, Volume: 37, Issue:10

    Topics: Acetylcysteine; Animals; Hepatic Artery; Hydrogen Peroxide; Ischemia; Liver Circulation; Male; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Portal Vein; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tumor Necrosis Factor-alpha

2005
Concomitant administration of mannitol and N-acetylcysteine for the prevention of lung reperfusion injury.
    The Journal of trauma, 2006, Volume: 60, Issue:6

    Topics: Acetylcysteine; Animals; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Free Radical Scavengers; Ischemia; Liver; Lung; Male; Mannitol; Rats; Rats, Wistar; Reperfusion Injury

2006
Ischemia promotes calpain-mediated degradation of p120-catenin in SH-SY5Y cells.
    Biochemical and biophysical research communications, 2007, Feb-16, Volume: 353, Issue:3

    Topics: Acetylcysteine; Calpain; Catenins; Cell Adhesion Molecules; Cell Aggregation; Cell Death; Cell Line, Tumor; Delta Catenin; Dipeptides; Humans; Ischemia; Leupeptins; Neuroblastoma; Phosphoproteins

2007
The beneficial effect of N-acetylcysteine and ciprofloxacin therapy on the outcome of ischemic fulminant hepatic failure.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:12

    Topics: Acetylcysteine; Ciprofloxacin; Drug Therapy, Combination; Follow-Up Studies; Free Radical Scavengers; Humans; Ischemia; Liver; Liver Failure, Acute; Male; Middle Aged; Nucleic Acid Synthesis Inhibitors

2007
Comparisons between the beneficial effects of different sulphonylurea treatments on ischemia-induced retinal neovascularization.
    Free radical biology & medicine, 2007, Aug-01, Volume: 43, Issue:3

    Topics: Acetylcysteine; Animals; Blood Glucose; Female; Gliclazide; Glyburide; Ischemia; Mice; Oxidative Stress; Oxygen; Retina; Retinal Neovascularization; RNA, Messenger; Sulfonylurea Compounds; Vascular Endothelial Growth Factor A

2007
N-acetyl cysteine attenuates the inflammatory response in warm ischemic pig lungs.
    The Journal of surgical research, 2008, May-15, Volume: 146, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Disease Models, Animal; Inflammation; Ischemia; Lung; Lung Transplantation; Organ Preservation; Reperfusion Injury; Swine; Temperature

2008
Hydrophobicity of mucosal surface and its relationship to gut barrier function.
    Shock (Augusta, Ga.), 2008, Volume: 29, Issue:3

    Topics: Acetylcysteine; Animals; Expectorants; Hydrophobic and Hydrophilic Interactions; Intestinal Mucosa; Ischemia; Male; Mucus; Permeability; Rats; Rats, Sprague-Dawley

2008
Inhibition of brain creatine kinase activity after renal ischemia is attenuated by N-acetylcysteine and deferoxamine administration.
    Neuroscience letters, 2008, Mar-21, Volume: 434, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Brain; Brain Diseases, Metabolic; Creatine Kinase; Deferoxamine; Down-Regulation; Ischemia; Kidney Diseases; Male; Nerve Degeneration; Oxidative Stress; Rats; Rats, Wistar; Subcellular Fractions; Time Factors; Treatment Outcome; Uremia

2008
Hyperbaric oxygen attenuates apoptosis and decreases inflammation in an ischemic wound model.
    The Journal of investigative dermatology, 2008, Volume: 128, Issue:8

    Topics: Acetylcysteine; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cyclooxygenase 2; Free Radical Scavengers; Hyperbaric Oxygenation; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Ischemia; Male; Membrane Proteins; Mitochondrial Proteins; Models, Animal; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Signal Transduction; Tumor Suppressor Protein p53; Vascular Endothelial Growth Factor A; Wound Healing; Wounds and Injuries

2008
Role of mucus in gastric mucosal injury induced by local ischemia/reperfusion.
    The Journal of laboratory and clinical medicine, 1995, Volume: 126, Issue:3

    Topics: Acetylcysteine; Alcian Blue; Animals; Chromium Radioisotopes; Diterpenes; Edetic Acid; Gastric Mucosa; Hexosamines; Ischemia; Male; Mucus; Periodic Acid-Schiff Reaction; Rats; Rats, Sprague-Dawley; Reperfusion Injury

1995
N-acetylcysteine ameliorates reperfusion injury after warm hepatic ischemia.
    Transplantation, 1995, Jan-15, Volume: 59, Issue:1

    Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Aspartate Aminotransferases; Bile; Glutathione; Hot Temperature; Ischemia; L-Lactate Dehydrogenase; Liver; Oxidative Stress; Reperfusion Injury; Swine

1995
Evidence that S-adenosylmethionine and N-acetylcysteine reduce injury from sequential cold and warm ischemia in the isolated perfused rat liver.
    Transplantation, 1994, Apr-27, Volume: 57, Issue:8

    Topics: Acetylcysteine; Animals; Aspartate Aminotransferases; Bile; Cold Temperature; Hot Temperature; Ischemia; Liver; Male; Oxygen; Oxygen Consumption; Rats; Rats, Inbred Lew; Regional Blood Flow; Reperfusion Injury; S-Adenosylmethionine; Time Factors

1994
N-acetylcysteine attenuates cold ischemia/reperfusion injury in the isolated perfused rat liver.
    Transplantation proceedings, 1993, Volume: 25, Issue:2

    Topics: Acetylcysteine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Bile; Cold Temperature; Glutathione; Ischemia; L-Lactate Dehydrogenase; Liver; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury

1993
Impact of N-acetylcysteine on the hepatic microcirculation after orthotopic liver transplantation.
    Transplantation, 1996, May-15, Volume: 61, Issue:9

    Topics: Acetylcysteine; Animals; Cold Temperature; Free Radical Scavengers; Ischemia; Liver Circulation; Liver Transplantation; Male; Microcirculation; Organ Preservation; Rats; Rats, Inbred Lew; Reperfusion Injury

1996
New ET-Kyoto solution containing N-acetylcysteine, nitroglycerin, and dibutyryl cyclic AMP provides reliable 30-hour canine lung preservation.
    Transplantation proceedings, 1996, Volume: 28, Issue:3

    Topics: Acetylcysteine; Adenosine; Allopurinol; Analysis of Variance; Animals; Bucladesine; Dogs; Endothelium, Vascular; Gluconates; Glutathione; Hydroxyethyl Starch Derivatives; Insulin; Ischemia; Lung; Lung Transplantation; Microscopy, Electron, Scanning; Nitroglycerin; Organ Preservation; Organ Preservation Solutions; Oxygen; Phosphates; Raffinose; Time Factors; Trehalose

1996
N-acetyl cysteine ameliorates ischemic renal failure.
    The American journal of physiology, 1997, Volume: 272, Issue:3 Pt 2

    Topics: Acetylcysteine; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Genes, fos; Genes, jun; Ischemia; JNK Mitogen-Activated Protein Kinases; Kidney; Kidney Tubules, Proximal; Male; Mitogen-Activated Protein Kinases; Necrosis; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Renal Insufficiency; Reperfusion; RNA, Messenger; Transcription, Genetic

1997
The effects of N-acetylcysteine and anti-intercellular adhesion molecule-1 monoclonal antibody against ischemia-reperfusion injury of the rat steatotic liver produced by a choline-methionine-deficient diet.
    Hepatology (Baltimore, Md.), 1997, Volume: 26, Issue:3

    Topics: Acetylcysteine; Acid Phosphatase; Alanine Transaminase; Animals; Antibodies, Monoclonal; Aspartate Aminotransferases; Bile; Choline Deficiency; Fatty Liver; In Vitro Techniques; Intercellular Adhesion Molecule-1; Ischemia; L-Lactate Dehydrogenase; Liver; Male; Malondialdehyde; Methionine; Microscopy, Electron; Neutrophils; Perfusion; Rats; Rats, Wistar; Reperfusion Injury

1997
Protective effect of N-acetyl-L-cysteine on the renal failure induced by inferior vena cava occlusion.
    Transplantation, 1998, May-27, Volume: 65, Issue:10

    Topics: Acetylcholine; Acetylcysteine; Acute Kidney Injury; Animals; Constriction; Dogs; Enzyme Inhibitors; Female; Free Radical Scavengers; Injections, Intra-Arterial; Ischemia; Kidney; Male; NG-Nitroarginine Methyl Ester; Renal Circulation; Reperfusion; Vena Cava, Inferior

1998
Effect of reactive oxygen species on iron regulatory protein activity.
    Annals of the New York Academy of Sciences, 1998, Jun-30, Volume: 851

    Topics: Acetylcysteine; Animals; Down-Regulation; Ferritins; Iron; Iron-Regulatory Proteins; Iron-Sulfur Proteins; Ischemia; Liver; Oxidation-Reduction; Oxidative Stress; Proto-Oncogene Proteins; Rats; Reactive Oxygen Species; RNA-Binding Proteins; Wnt2 Protein; Xanthine; Xanthine Oxidase

1998
Pentoxifylline and N-acetylcysteine in hepatic ischemia/reperfusion injury.
    Clinica chimica acta; international journal of clinical chemistry, 1998, Jul-28, Volume: 275, Issue:2

    Topics: Acetylcysteine; Animals; Catalase; Female; Free Radical Scavengers; Free Radicals; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Ischemia; Lipid Peroxidation; Liver; Malondialdehyde; Pentoxifylline; Rats; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase; Vasodilator Agents

1998
Somatostatine does not decrease intestinal necrosis in an ischemia-reperfusion experimental model.
    Transplantation proceedings, 1998, Volume: 30, Issue:6

    Topics: Acetylcysteine; Amylases; Animals; Biomarkers; Glutathione; Intestine, Small; Ischemia; Malondialdehyde; Myocardium; Necrosis; Peroxidase; Rats; Rats, Wistar; Reperfusion; Somatostatin

1998
Allopurinol and N-acetylcysteine avoid 60% of intestinal necrosis in an ischemia-reperfusion experimental model.
    Transplantation proceedings, 1998, Volume: 30, Issue:6

    Topics: Acetylcysteine; Allopurinol; Animals; Glutathione; Intestine, Small; Ischemia; Lung; Malondialdehyde; Myocardium; Necrosis; Rats; Rats, Wistar; Reperfusion; Reperfusion Injury

1998
N-acetylcysteine and anti-ICAM-1 monoclonal antibody reduce ischemia-reperfusion injury of the steatotic rat liver.
    Transplantation proceedings, 1998, Volume: 30, Issue:7

    Topics: Acetylcysteine; Adenosine; Allopurinol; Animals; Antibodies, Monoclonal; Choline Deficiency; Fatty Liver; Glutathione; Insulin; Intercellular Adhesion Molecule-1; Ischemia; Liver; Male; Methionine; Organ Preservation; Organ Preservation Solutions; Raffinose; Rats; Rats, Wistar; Reperfusion Injury

1998
Free radical scavengers to prevent reperfusion injury following experimental warm liver ischaemia. Is there a real physiological benefit?
    Transplant international : official journal of the European Society for Organ Transplantation, 1999, Volume: 12, Issue:3

    Topics: Acetylcysteine; Allopurinol; Animals; Free Radical Scavengers; Galactose; Ischemia; Liver; Liver Function Tests; Male; Microcirculation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase; Vitamin E

1999
Hepatic ischemia/reperfusion in rats induces iNOS gene transcription by activation of NF-kappaB.
    Biochemical and biophysical research communications, 1999, Aug-11, Volume: 261, Issue:3

    Topics: Acetylcysteine; Animals; Antioxidants; Dimerization; Gene Expression; Ischemia; Kinetics; Liver; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion; RNA, Messenger

1999
Free radical scavengers to prevent reperfusion injury following warm liver ischemia.
    Transplantation proceedings, 1999, Volume: 31, Issue:6

    Topics: Acetylcysteine; Allopurinol; Animals; Free Radical Scavengers; Ischemia; Liver; Liver Circulation; Male; Microcirculation; Organ Preservation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase; Temperature; Time Factors; Vitamin E

1999
Prevention by somatostatine and N-acetylcisteine of multiorgan failure mediated by oxidative stress after intestinal ischemia.
    Transplantation proceedings, 1999, Volume: 31, Issue:6

    Topics: Acetylcysteine; Adenosine Triphosphate; Allopurinol; Animals; Glutathione; Heart; Intestine, Small; Ischemia; Liver; Lung; Malondialdehyde; Mesenteric Arteries; Multiple Organ Failure; Myocardium; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Somatostatin

1999
Ischemia-reperfusion injury of rabbit kidney: comparative effects of desferrioxamine and N-acetylcysteine as antioxidants.
    Transplantation proceedings, 2000, Volume: 32, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Aspartate Aminotransferases; Deferoxamine; Glutathione; Ischemia; Kidney; Kidney Cortex; L-Lactate Dehydrogenase; Microcirculation; Necrosis; Rabbits; Renal Circulation; Reperfusion Injury; Vitamin E

2000
N-acetyl-L-cysteine for preventing lung reperfusion injury after liver ischemia-reperfusion: a possible dual protective mechanism in a dose-response study.
    Transplantation, 2000, Mar-15, Volume: 69, Issue:5

    Topics: Acetylcysteine; Animals; Dose-Response Relationship, Drug; Free Radical Scavengers; Glutathione; Ischemia; Liver; Liver Circulation; Lung; Lung Diseases; Male; Perfusion; Pulmonary Circulation; Rats; Rats, Wistar; Reperfusion Injury; Respiration; Xanthine Oxidase

2000
Gaseous oxygen for hypothermic preservation of predamaged liver grafts: fuel to cellular homeostasis or radical tissue alteration?
    Cryobiology, 2000, Volume: 40, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Cell Hypoxia; Cryopreservation; Free Radicals; Gases; Homeostasis; Infusions, Intravenous; Insufflation; Ischemia; Liver; Liver Transplantation; Male; Organ Preservation; Oxidative Stress; Oxygen; Perfusion; Rats; Superoxide Dismutase; Tissue and Organ Procurement; Tissue Donors; Vena Cava, Inferior

2000
Preventive effect of lactacystin, a selective proteasome inhibitor, on ischemic acute renal failure in rats.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 298, Issue:2

    Topics: Acetylcysteine; Acute Kidney Injury; Animals; Blood Urea Nitrogen; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Endothelin-1; Ischemia; Kidney; Male; Multienzyme Complexes; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Renal Circulation; Reperfusion Injury

2001
Reactive oxygen intermediates induce monocyte chemotactic protein-1 in vascular endothelium after brief ischemia.
    The American journal of pathology, 2001, Volume: 159, Issue:4

    Topics: Acetylcysteine; Animals; Cells, Cultured; Chemokine CCL2; Dogs; Endothelium, Vascular; Free Radical Scavengers; Hydrogen Peroxide; Ischemia; Myocardium; NF-kappa B; Oxidants; Pyrrolidines; Reactive Oxygen Species; RNA, Messenger; Thiocarbamates; Tissue Distribution; Transcription Factor AP-1; Venules

2001
Enhancement of ischaemic rabbit skin flap survival with the antioxidant and free-radical scavenger N-acetylcysteine.
    Clinical science (London, England : 1979), 1991, Volume: 81, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Disease Models, Animal; Free Radical Scavengers; Graft Survival; Ischemia; Malondialdehyde; Phenylhydrazines; Rabbits; Reperfusion Injury; Skin; Surgical Flaps; Thromboxane B2; Vascular Resistance

1991
Glutathione catabolism by the ischemic rat kidney.
    The American journal of physiology, 1990, Volume: 258, Issue:6

    Topics: Acetylcysteine; Animals; Antimetabolites; Cysteine; gamma-Glutamyltransferase; Glutathione; Ischemia; Isoxazoles; Kidney; Male; Rats; Reperfusion; Sulfhydryl Compounds

1990