acetylcysteine has been researched along with Insulin Sensitivity in 56 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (5.36) | 18.2507 |
| 2000's | 18 (32.14) | 29.6817 |
| 2010's | 23 (41.07) | 24.3611 |
| 2020's | 12 (21.43) | 2.80 |
| Authors | Studies |
|---|---|
| Billig, H; Brännström, M; Hu, M; Li, J; Liang, M; Ma, H; Ma, S; Sferruzzi-Perri, AN; Shao, LR; Wang, X; Wu, X; Zhang, Y | 1 |
| Hsu, JW; Jahoor, F; Kumar, P; Liu, C; Minard, CG; Muthupillai, R; Sekhar, RV; Suliburk, J; Taffet, GE | 1 |
| Kang, J; Liu, S; Shen, Q; Wu, H; Yao, Q; Zou, X | 1 |
| Maciejczyk, M; Szarmach, I; Zalewska, A; Żendzian-Piotrowska, M | 1 |
| Comin, VH; Luiz, KD; Pieri, BLDS; Rodrigues, MS; Silveira, GB; Silveira, PCL; Venturini, LM; Zaccaron, RP | 1 |
| Atlan, M; Béréziat, V; Bourgeois, C; Capeau, J; Desjardins, D; Ejlalmanesh, T; Fève, B; Gorwood, J; Lagathu, C; Lambotte, O; Le Grand, R; Mantecon, M; Rose, C | 1 |
| Charron, MJ; Chaurasia, B; Du, XQ; Katz, EB; Reznik, SE; Saghatelian, A; Seki, Y; Summers, SA; Vuguin, PM; Williams, L | 1 |
| Chang, CS; Chang, YH; Chuang, JH; Lian, WS; Lin, CY; Lin, HY; Lin, TK; Liou, CW; Shen, FC; Su, YJ; Tsao, CF; Wang, PW; Weng, SW | 1 |
| Kossakowska, A; Kostecka-Sochoń, P; Maciejczyk, M; Matczuk, J; Zalewska, A; Żendzian-Piotrowska, M; Zięba, S | 1 |
| Abd El-Aziz, EA; Abdelhaffez, AS; Ahmed, AM; Tohamy, MB | 1 |
| Chacko, S; Hsu, JW; Jahoor, F; Kumar, P; Liu, C; Minard, C; Sekhar, RV | 1 |
| He, YL; Li, XM; Nie, F; Xiong, Y; Zhou, XK | 1 |
| Bernlohr, DA; Burrill, JS; Hahn, WS; Kim, DH; Kuzmicic, J; Olson, DH; Park, JM | 1 |
| Barquissau, V; Capel, F; Chauvin, MA; Dardevet, D; Feillet-Coudray, C; Gallinier, A; Morio, B; Rieusset, J | 1 |
| Chang, CS; Chuang, JH; Lian, WS; Lin, CY; Lin, HY; Lin, TK; Liou, CW; Shen, FC; Tsao, CF; Wang, PW; Weng, SW | 1 |
| Arbelaez, LG; Castro, MC; Francini, F; Massa, ML; Schinella, G; Spinedi, E; Villagarcía, HG | 1 |
| Kurek, K; Maciejczyk, M; Matczuk, J; Waszkiel, D; Zalewska, A; Żendzian-Piotrowska, M; Żukowski, P | 1 |
| Feng, J; Ge, CX; Gu, TT; Hu, LF; Huang, P; Li, Q; Lou, DS; Qin, YT; Tan, J; Xu, MX | 1 |
| Abd El Aziz, WM; El Sharkwy, IA | 1 |
| Baskaran, SK; Lakshmi, BS; Posa, JK; Sangeetha, KN; Selvaraj, S | 1 |
| Cheng, J; Hisatome, I; Hu, Y; Huang, T; Li, Z; Luo, C; Luo, Y; Yamamoto, T; Yuan, H; Zhang, Y; Zhu, Y | 1 |
| Chauvin, MA; Croze, ML; Géloën, A; Guichardant, M; Koppe, L; Pesenti, S; Pillon, NJ; Rieusset, J; Soulage, CO; Vella, RE; Zarrouki, B | 1 |
| Abdelmoula, J; Annabi, A; Bouzid, K; Douib, IB; El Fazaa, S; El-Golli, N; Gharbi, N; Lamine, AJ; Lasram, MM | 1 |
| George Fantus, I; Giacca, A; Joseph, JW; Pereira, S; Shah, A | 1 |
| Annabi, A; Dhouib, IB; El Fazaa, S; Gharbi, N; Lasram, MM | 1 |
| Chen, H; Fan, HQ; He, W; Wang, ZX; Xu, KF; Xu, XY | 1 |
| Chibalin, AV; Levinger, I; Lundell, LS; McQuade, LR; Patil, KV; Perry, BD; Stepto, NK; Trewin, AJ | 1 |
| Babenko, NA; Belyĭ, AN; Timofiĭchuk, OA | 1 |
| Attanasio, R; Feroe, AG; Scinicariello, F | 1 |
| Cheng, J; Hisatome, I; Hong, L; Hu, Y; Li, Z; Luo, C; Wen, T; Yamamoto, T; Yuan, H; Zhang, X; Zhang, Y; Zhu, Y; Zhuang, W; Zou, J | 1 |
| Ge, X; Qi, W; Shi, X; Yu, Q; Zhai, Q | 1 |
| Couture, R; de Champlain, J; El Midaoui, A; Fantus, IG; Ismael, MA; Lu, H | 1 |
| Aw, TY; Okayama, N; Okouchi, M | 1 |
| Andrikopoulos, S; Boivin, B; Bruce, C; Cai, X; Crack, PJ; Deng, H; Febbraio, MA; Fukushima, A; Galic, S; Loh, K; Mitchell, CA; Ooms, LM; Shields, BJ; Skiba, B; Stepto, N; Tiganis, T; Tonks, NK; Watt, MJ; Wu, B | 1 |
| Lautt, WW; Legare, DJ; Macedo, MP; Schafer, J | 1 |
| Chen, WC; de la Monte, SM; Longato, L; Petersen, DR; Ronis, M; Setshedi, M; Wands, JR | 1 |
| Muderris, II; Oner, G | 1 |
| Bershteĭn, LM; Boiarkina, MP; Kisel'nikov, KS; Kovalenko, IG; Poroshina, TE; Vasil'ev, DA; Zaĭtsev, AN | 1 |
| Burdelova, EO; Fishman, S; Halpern, Z; Hoffman, S; Rechtman, MM; Shlomai, A; Sklan, EH; Solar, I; Zilberberg, A | 1 |
| Bogdanovic, E; Fantus, IG; Giacca, A; Goh, T; Gupta, N; Haber, CA; Lam, TK; Yu, Z | 1 |
| Anfossi, G; Massucco, P; Mattiello, L; Russo, I; Trovati, M | 1 |
| Delvin, E; Lambert, M; Levy, E; Seidman, E; Ziv, E; Zoltowska, M | 1 |
| Kilic-Okman, T; Kucuk, M | 1 |
| Hutchings, S; Pang, CC; Song, D | 1 |
| Bashan, N; Ben-Romano, R; Etzion, S; Greenbaum, U; Kagan, E; Potashnik, R; Rudich, A | 1 |
| Qian, Z; Sun, S; Xi, L; Xu, G; Zhou, C | 1 |
| Jia, X; Wu, L | 1 |
| Fujioka, D; Kawabata, K; Kitta, Y; Kobayashi, T; Kodama, Y; Kugiyama, K; Nakamura, T; Obata, JE; Saito, Y; Takano, H; Yano, T | 1 |
| Adachi, Y; Sakurai, H; Yoshikawa, Y | 1 |
| Li, HL; Wang, B; Yang, WY | 1 |
| Dröge, W; Hack, V; Ushmorov, A | 1 |
| Fujitani, Y; Hanafusa, T; Hori, M; Kajimoto, Y; Kaneto, H; Matsuoka, T; Matsuzawa, Y; Miyagawa, J; Umayahara, Y; Yamasaki, Y | 1 |
| Ford, CA; Gadag, V; Longerich, L; Parai, S; Vasdev, S; Wadhawan, S | 1 |
| Bogdanovic, E; Ennis, D; Fantus, C; Fantus, IG; Lai, R; Le-Tien, H; Lu, B; Nikolov, R; Salamon, L | 1 |
| Buse, MG; Greene, EL; Nelson, BA; Robinson, KA | 1 |
| Ayala, GF; Belosi, C; Ciampelli, M; Fulghesu, AM; Lanzone, A; Muzj, G; Selvaggi, L | 1 |
1 review(s) available for acetylcysteine and Insulin Sensitivity
| Article | Year |
|---|---|
A review on the possible molecular mechanism of action of N-acetylcysteine against insulin resistance and type-2 diabetes development.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Diabetes Mellitus, Type 2; Humans; Insulin Resistance | 2015 |
5 trial(s) available for acetylcysteine and Insulin Sensitivity
| Article | Year |
|---|---|
Supplementing Glycine and N-Acetylcysteine (GlyNAC) in Older Adults Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Physical Function, and Aging Hallmarks: A Randomized Clinical Trial.
Topics: Acetylcysteine; Aged; Aging; Animals; Dietary Supplements; Glutathione; Glycine; Health Promotion; Humans; Inflammation; Insulin Resistance; Mice; Mitochondria; Oxidative Stress | 2023 |
Randomized controlled trial of N-acetylcysteine versus l-carnitine among women with clomiphene-citrate-resistant polycystic ovary syndrome.
Topics: Acetylcysteine; Adult; Carnitine; Clomiphene; Double-Blind Method; Female; Follicle Stimulating Hormone; Humans; Infertility, Female; Insulin Resistance; Ovulation; Ovulation Induction; Polycystic Ovary Syndrome; Pregnancy; Pregnancy Rate; Young Adult | 2019 |
Effect of N-acetylcysteine infusion on exercise-induced modulation of insulin sensitivity and signaling pathways in human skeletal muscle.
Topics: Acetylcysteine; Adult; Cross-Over Studies; Double-Blind Method; Exercise; Exercise Test; Female; Glucose Clamp Technique; Humans; Infusions, Intravenous; Insulin; Insulin Resistance; Male; Muscle Contraction; Muscle, Skeletal; Reactive Oxygen Species; Signal Transduction; Young Adult | 2015 |
Clinical, endocrine and metabolic effects of metformin vs N-acetyl-cysteine in women with polycystic ovary syndrome.
Topics: Acetylcysteine; Adolescent; Adult; Anticholesteremic Agents; Antioxidants; Body Mass Index; Female; Hirsutism; Humans; Hyperandrogenism; Hypercholesterolemia; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Menstruation Disturbances; Metformin; Patient Dropouts; Polycystic Ovary Syndrome; Severity of Illness Index; Tumor Necrosis Factor-alpha; Young Adult | 2011 |
N-acetyl-cysteine treatment improves insulin sensitivity in women with polycystic ovary syndrome.
Topics: Acetylcysteine; Adult; Androgens; Drug Administration Schedule; Female; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Liver; Polycystic Ovary Syndrome; Prospective Studies; Testosterone | 2002 |
50 other study(ies) available for acetylcysteine and Insulin Sensitivity
| Article | Year |
|---|---|
Suppression of uterine and placental ferroptosis by N-acetylcysteine in a rat model of polycystic ovary syndrome.
Topics: Acetylcysteine; Animals; Antioxidants; Dihydrotestosterone; Disease Models, Animal; Female; Ferroptosis; Glutathione; Insulin Resistance; Iron; Male; Malondialdehyde; Mitochondria; Oxidative Phosphorylation; Phospholipid Hydroperoxide Glutathione Peroxidase; Placenta; Polycystic Ovary Syndrome; Pregnancy; Rats, Sprague-Dawley; Signal Transduction; Uterus | 2021 |
Oxidative Stress as a Contributor to Insulin Resistance in the Skeletal Muscles of Mice with Polycystic Ovary Syndrome.
Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Dehydroepiandrosterone; Female; Humans; Insulin Resistance; Mice; Mice, Inbred C57BL; Muscle, Skeletal; NADP; Oxidative Stress; Oxidoreductases; Polycystic Ovary Syndrome; Reactive Oxygen Species; Receptors, Androgen; Testosterone | 2022 |
The Effect of N-Acetylcysteine on Respiratory Enzymes, ADP/ATP Ratio, Glutathione Metabolism, and Nitrosative Stress in the Salivary Gland Mitochondria of Insulin Resistant Rats.
Topics: Acetylcysteine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apoptosis; Cytokines; Diet, High-Fat; Electron Transport Complex IV; Energy Metabolism; Glutathione; Hydrogen Peroxide; Insulin Resistance; Male; Mitochondria; Nitrosative Stress; Rats, Wistar; Salivary Glands | 2020 |
Reduction of oxidative stress improves insulin signaling in cardiac tissue of obese mice.
Topics: Acetylcysteine; Animals; Blood Glucose; Blotting, Western; Body Weight; Diet, High-Fat; Fluoresceins; Free Radical Scavengers; Humans; Insulin Resistance; Male; Mice; Myocardium; Obesity; Oxidative Stress; Protein Carbonylation; Reactive Oxygen Species; Reference Values; Spectrophotometry | 2020 |
SIV Infection and the HIV Proteins Tat and Nef Induce Senescence in Adipose Tissue and Human Adipose Stem Cells, Resulting in Adipocyte Dysfunction.
Topics: Acetylcysteine; Adipocytes; Adipogenesis; Adipose Tissue; Animals; Cellular Senescence; Humans; Insulin Resistance; Interleukin-6; Interleukin-8; Macaca fascicularis; Mitochondria; nef Gene Products, Human Immunodeficiency Virus; Oxidative Stress; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Stem Cells; tat Gene Products, Human Immunodeficiency Virus | 2020 |
Antioxidant Effects of N-Acetylcysteine Prevent Programmed Metabolic Disease in Mice.
Topics: Acetylcysteine; Adipose Tissue, Brown; Adipose Tissue, White; Adiposity; Animals; Antioxidants; Body Temperature; Calorimetry, Indirect; Diet, High-Fat; Female; Glucose Tolerance Test; Inflammation; Injections, Intraperitoneal; Insulin Resistance; Male; Metabolic Diseases; Mice; Weight Gain | 2020 |
Legacy Effect of Antioxidant N-acetylcysteine in Cellular Senescence of Diet-induced Obesity Mice.
Topics: Acetylcysteine; Animals; Antioxidants; Cellular Senescence; Diet, High-Fat; Insulin Resistance; Male; Mice; Obesity | 2021 |
NAC Supplementation of Hyperglycemic Rats Prevents the Development of Insulin Resistance and Improves Antioxidant Status but Only Alleviates General and Salivary Gland Oxidative Stress.
Topics: Acetylcysteine; Animals; Free Radical Scavengers; Hyperglycemia; Insulin Resistance; Male; Oxidative Stress; Rats; Rats, Wistar; Salivary Glands | 2020 |
N-acetyl cysteine can blunt metabolic and cardiovascular effects via down-regulation of cardiotrophin-1 in rat model of fructose-induced metabolic syndrome.
Topics: Acetylcysteine; Animals; Aorta; Down-Regulation; Fibrosis; Fructose; Insulin Resistance; Male; Metabolic Syndrome; Oxidative Stress; Rats; Rats, Wistar | 2023 |
Glycine and N-acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity, muscle strength, and cognition: Re
Topics: Acetylcysteine; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Cognition; Dietary Supplements; DNA Damage; Endothelium; Female; Free Radical Scavengers; Geriatric Assessment; Glutathione; Glycine; Glycine Agents; Humans; Inflammation; Insulin Resistance; Male; Mitochondria; Muscle Strength; Oxidative Stress; Pilot Projects; Young Adult | 2021 |
Endogenous asymmetric dimethylarginine accumulation precipitates the cardiac and mitochondrial dysfunctions in type 1 diabetic rats.
Topics: Acetylcysteine; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Free Radical Scavengers; Glycosylation; Heart Diseases; Insulin Resistance; Male; Mitochondria; Myocardial Contraction; Myocytes, Cardiac; Nitric Oxide; Papillary Muscles; Rats, Sprague-Dawley; Signal Transduction; Streptozocin | 2021 |
Down regulation of Peroxiredoxin-3 in 3T3-L1 adipocytes leads to oxidation of Rictor in the mammalian-target of rapamycin complex 2 (mTORC2).
Topics: 3T3-L1 Cells; Acetylcysteine; Adipocytes; Animals; Biological Transport; Carrier Proteins; Down-Regulation; Glucose; Insulin; Insulin Resistance; Mechanistic Target of Rapamycin Complex 2; Mice; Mice, Inbred C57BL; Mitochondria; Multiprotein Complexes; Oxidation-Reduction; Oxidative Stress; Peroxiredoxin III; Phosphorylation; Proto-Oncogene Proteins c-akt; Rapamycin-Insensitive Companion of mTOR Protein; TOR Serine-Threonine Kinases | 2017 |
Reactive oxygen species enhance mitochondrial function, insulin sensitivity and glucose uptake in skeletal muscle of senescence accelerated prone mice SAMP8.
Topics: Acetylcysteine; Animals; Antioxidants; Biological Transport; Electron Transport Complex I; Electron Transport Complex II; Electron Transport Complex IV; Female; Gene Expression Regulation; Glucose; Insulin; Insulin Resistance; Mice; Mice, Transgenic; Mitochondria, Muscle; Muscle, Skeletal; Oxidative Stress; Phosphorylation; Progeria; Protein Carbonylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Xanthine Oxidase | 2017 |
Early intervention of N-acetylcysteine better improves insulin resistance in diet-induced obesity mice.
Topics: Acetylcysteine; Animals; Diet; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mitochondria; Obesity; Reactive Oxygen Species; Secondary Prevention | 2018 |
N-Acetyl-l-Cysteine treatment efficiently prevented pre-diabetes and inflamed-dysmetabolic liver development in hypothalamic obese rats.
Topics: Acetylcysteine; Animals; Antioxidants; Blood Glucose; Hypothalamus; Insulin Resistance; Liver; Male; Obesity; Oxidative Stress; Prediabetic State; Rats; Rats, Wistar; Treatment Outcome | 2018 |
Effect of N-Acetylcysteine on Antioxidant Defense, Oxidative Modification, and Salivary Gland Function in a Rat Model of Insulin Resistance.
Topics: Acetylcysteine; Animals; Antioxidants; Disease Models, Animal; Insulin Resistance; Male; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Salivary Glands | 2018 |
Prolonged PM2.5 exposure elevates risk of oxidative stress-driven nonalcoholic fatty liver disease by triggering increase of dyslipidemia.
Topics: Acetylcysteine; Air Pollutants; Animals; Dyslipidemias; Hepatocytes; Humans; Inflammation; Insulin Resistance; Lipid Metabolism; Liver; Metabolic Syndrome; Mice; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Particulate Matter; Pyrrolidines; Signal Transduction; Thiocarbamates | 2019 |
p53 mediates impaired insulin signaling in 3T3-L1 adipocytes during hyperinsulinemia.
Topics: 3T3-L1 Cells; Acetylcysteine; Adipocytes; Animals; Cell Differentiation; Free Radical Scavengers; Glucose; Hyperinsulinism; Insulin; Insulin Resistance; Mice; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Signal Transduction; Tumor Suppressor Protein p53 | 2014 |
High uric acid directly inhibits insulin signalling and induces insulin resistance.
Topics: Acetylcysteine; Animals; Antioxidants; Disease Models, Animal; Glucose Intolerance; Hep G2 Cells; Humans; Hyperuricemia; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Uric Acid | 2014 |
Ozone exposure triggers insulin resistance through muscle c-Jun N-terminal kinase activation.
Topics: Acetylcysteine; Animals; Anthracenes; Bronchoalveolar Lavage Fluid; Cell Line; Enzyme Activation; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; Mice; Ozone; Phenylbutyrates; Rats | 2015 |
Changes in glucose metabolism and reversion of genes expression in the liver of insulin-resistant rats exposed to malathion. The protective effects of N-acetylcysteine.
Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Cholinesterase Inhibitors; Free Radical Scavengers; Gene Expression Regulation; Glucose; Glycerol Kinase; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Insulin; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Liver; Malathion; Male; Oxidative Stress; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Wistar; Signal Transduction | 2015 |
Effect of N-acetyl-l-cysteine on insulin resistance caused by prolonged free fatty acid elevation.
Topics: Acetylcysteine; Animals; Biomarkers; Blood Glucose; Emulsions; Fatty Acids, Nonesterified; Female; Free Radical Scavengers; Glucose; Heparin; Insulin Resistance; Oxidative Stress; Phospholipids; Rats; Rats, Wistar; Soybean Oil | 2015 |
FTO Inhibits Insulin Secretion and Promotes NF-κB Activation through Positively Regulating ROS Production in Pancreatic β cells.
Topics: Acetylcysteine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Diabetes Mellitus, Type 2; Gene Expression Regulation; Glucose; Insulin; Insulin Resistance; Insulin-Secreting Cells; Islets of Langerhans; Mice; Mice, Inbred C57BL; Mixed Function Oxygenases; NF-kappa B; Oxo-Acid-Lyases; Reactive Oxygen Species; Receptors, G-Protein-Coupled; Signal Transduction | 2015 |
[ROLE OF NEUTRAL SPHINGOMYELINASE IN AGE-DEPENDENT MUSCLE INSULIN RESISTANCE DEVELOPMENT AND ITS IMPROVEMENT WITH N-ACETYLCYSTEINE].
Topics: Acetylcysteine; Animals; Ceramides; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Male; Muscle, Skeletal; Rats | 2015 |
Acrolein metabolites, diabetes and insulin resistance.
Topics: Acetylcysteine; Acrolein; Adult; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Humans; Insulin Resistance; Male; Nutrition Surveys | 2016 |
Metformin ameliorates high uric acid-induced insulin resistance in skeletal muscle cells.
Topics: 4-Chloro-7-nitrobenzofurazan; Acetylcysteine; Adenylate Kinase; Animals; Antioxidants; Cell Line; Deoxyglucose; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Metformin; Mice; Models, Biological; Muscle Cells; Muscle, Skeletal; Oxidative Stress; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Uric Acid | 2017 |
Chronic insulin treatment causes insulin resistance in 3T3-L1 adipocytes through oxidative stress.
Topics: 3T3-L1 Cells; Acetylcysteine; Adipocytes; Animals; Antioxidants; Catalase; Endoplasmic Reticulum; Glucose; Insulin; Insulin Resistance; MAP Kinase Kinase 4; Mice; Models, Biological; Oxidative Stress; Reactive Oxygen Species | 2008 |
Comparative effects of N-acetyl-L-cysteine and ramipril on arterial hypertension, insulin resistance, and oxidative stress in chronically glucose-fed rats.
Topics: Acetylcysteine; Aldehydes; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Blood Pressure; Diet; Free Radical Scavengers; Glucose; Hypertension; Insulin Receptor Substrate Proteins; Insulin Resistance; Lipid Peroxidation; Liver; Male; Malondialdehyde; Muscle, Skeletal; NADPH Oxidases; Oxidative Stress; Oxygen Consumption; Ramipril; Rats; Rats, Wistar | 2008 |
Preservation of cellular glutathione status and mitochondrial membrane potential by N-acetylcysteine and insulin sensitizers prevent carbonyl stress-induced human brain endothelial cell apoptosis.
Topics: Acetylcysteine; Apoptosis; Brain; Caspase 8; Caspase 9; Cell Line; Endothelial Cells; Fluorescent Dyes; Glutathione; Homeostasis; Humans; Hypoglycemic Agents; Indoles; Insulin; Insulin Resistance; Membrane Potentials; Mitochondrial Membranes; Oxidation-Reduction; Oxidative Stress; Poly(ADP-ribose) Polymerases; Protein Carbonylation | 2009 |
Reactive oxygen species enhance insulin sensitivity.
Topics: Acetylcysteine; Animals; Antioxidants; Cells, Cultured; Energy Metabolism; Female; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Insulin; Insulin Resistance; Male; Mice; Mice, Knockout; Motor Activity; Obesity; Oxidation-Reduction; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Reactive Oxygen Species; Signal Transduction | 2009 |
Bethanechol and N-acetylcysteine mimic feeding signals and reverse insulin resistance in fasted and sucrose-induced diabetic rats.
Topics: Acetylcysteine; Animals; Bethanechol; Biomimetic Materials; Diabetes Mellitus, Experimental; Fasting; Feeding Behavior; Glutathione; Insulin; Insulin Resistance; Liver; Male; Muscarinic Agonists; Muscle, Skeletal; Parasympathetic Nervous System; Rats; Rats, Sprague-Dawley; Sucrose | 2011 |
Limited therapeutic effect of N-acetylcysteine on hepatic insulin resistance in an experimental model of alcohol-induced steatohepatitis.
Topics: Acetylcysteine; Alcoholism; Animals; Cytokines; Disease Models, Animal; Fatty Liver, Alcoholic; Insulin Resistance; Male; Rats; Rats, Sprague-Dawley | 2011 |
[The influence of metformin and N-acetylcysteine on mammographic density in postmenopausal women].
Topics: Acetylcysteine; Aged; Apoptosis; Breast; Breast Neoplasms; Cell Proliferation; DNA Repair; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Mammography; Metformin; Middle Aged; Neoplasms, Hormone-Dependent; Postmenopause; Risk Assessment; Risk Factors | 2012 |
The metabolic regulator PGC-1α links hepatitis C virus infection to hepatic insulin resistance.
Topics: Acetylcysteine; Cell Line, Tumor; Electroporation; Gene Knockdown Techniques; Genotype; Gluconeogenesis; Glucose-6-Phosphatase; Heat-Shock Proteins; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon-alpha; Liver; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Replicon; RNA, Messenger; RNA, Viral; Transcription Factors; Transcriptional Activation; Up-Regulation; Virus Replication | 2012 |
N-acetylcysteine and taurine prevent hyperglycemia-induced insulin resistance in vivo: possible role of oxidative stress.
Topics: Acetylcysteine; Animals; Blood Glucose; Glucose; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Oxidative Stress; Rats; Rats, Sprague-Dawley; Taurine | 2003 |
Platelet resistance to the antiaggregating effect of N-acetyl-L-cysteine in obese, insulin-resistant subjects.
Topics: Acetylcysteine; Adenosine Diphosphate; Adult; Amifostine; Antioxidants; Collagen; Cyclic GMP; Drug Resistance; Female; Free Radical Scavengers; Humans; Insulin Resistance; Male; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Nitroprusside; Obesity; Platelet Aggregation; Platelet Aggregation Inhibitors; Superoxide Dismutase | 2003 |
Both insulin resistance and diabetes in Psammomys obesus upregulate the hepatic machinery involved in intracellular VLDL assembly.
Topics: Acetylcysteine; Animals; Apolipoproteins B; Cells, Cultured; Cysteine Endopeptidases; Diabetes Mellitus; Disease Models, Animal; Gerbillinae; Hepatocytes; Hypercholesterolemia; Hyperinsulinism; Hypertriglyceridemia; Insulin; Insulin Resistance; Leupeptins; Lipoproteins, VLDL; Liver; Multienzyme Complexes; Protease Inhibitors; Proteasome Endopeptidase Complex | 2004 |
N-acetyl-cysteine treatment for polycystic ovary syndrome.
Topics: Acetylcysteine; Adult; Female; Free Radical Scavengers; Humans; Insulin Resistance; Polycystic Ovary Syndrome; Prospective Studies | 2004 |
Chronic N-acetylcysteine prevents fructose-induced insulin resistance and hypertension in rats.
Topics: Acetylcysteine; Adrenergic alpha-Agonists; Animals; Blood Pressure; Dinoprost; Dose-Response Relationship, Drug; Fructose; Glucose Tolerance Test; Hypertension; Insulin Resistance; Male; Methoxamine; Random Allocation; Rats; Rats, Sprague-Dawley; Triglycerides | 2005 |
Nelfinavir induces adipocyte insulin resistance through the induction of oxidative stress: differential protective effect of antioxidant agents.
Topics: 3T3-L1 Cells; Acetylcysteine; Adipocytes; Animals; Anti-HIV Agents; Antioxidants; Insulin; Insulin Resistance; Metalloporphyrins; Mice; Muscle, Smooth, Vascular; Nelfinavir; Oxidative Stress; Signal Transduction | 2006 |
Crocetin attenuates palmitate-induced insulin insensitivity and disordered tumor necrosis factor-alpha and adiponectin expression in rat adipocytes.
Topics: Acetylcysteine; Adipocytes; Adiponectin; Animals; Antimetabolites; Antioxidants; Blotting, Western; Carotenoids; Deoxyglucose; Glucose; Glucose Transporter Type 4; Insulin Resistance; Male; Onium Compounds; Palmitates; Rats; Rats, Wistar; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha; Vitamin A | 2007 |
Accumulation of endogenous methylglyoxal impaired insulin signaling in adipose tissue of fructose-fed rats.
Topics: 3T3-L1 Cells; Acetylcysteine; Adipocytes; Adipose Tissue; Animals; Diet; Fluorescent Antibody Technique; Fructose; Glucose; Glucose Tolerance Test; Immunoblotting; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mice; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Signal Transduction | 2007 |
Statin reverses reduction of adiponectin receptor expression in infarcted heart and in TNF-alpha-treated cardiomyocytes in association with improved glucose uptake.
Topics: Acetylcysteine; Adiponectin; Administration, Oral; Animals; Animals, Newborn; Antioxidants; Blood Glucose; Cells, Cultured; Coronary Vessels; Disease Models, Animal; Dose-Response Relationship, Drug; Fatty Acids; Glucose; Hydrogen Peroxide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Insulin Resistance; Ligation; Lipids; Male; Mice; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Oxidation-Reduction; Pravastatin; Rats; Rats, Sprague-Dawley; Receptors, Adiponectin; Recombinant Proteins; RNA Interference; RNA, Messenger; RNA, Small Interfering; Time Factors; Tumor Necrosis Factor-alpha | 2007 |
Antidiabetic zinc(II)-N-acetyl-L-cysteine complex: evaluations of in vitro insulinomimetic and in vivo blood glucose-lowering activities.
Topics: Acetylcysteine; Adipocytes; Animals; Antioxidants; Blood Glucose; Blood Urea Nitrogen; Cholesterol; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Evaluation, Preclinical; Glucose Tolerance Test; Hemoglobins; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Mice; Mice, Knockout; Oxidative Stress; Rats; Rats, Wistar; Zinc | 2007 |
[N-acetyl-l-cysteine improves function of islet beta cell in hyperlipidemic rats and its mechanism].
Topics: Acetylcysteine; Animals; Dietary Fats; Free Radical Scavengers; Hyperlipidemias; Insulin Resistance; Islets of Langerhans; Male; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Signal Transduction | 2007 |
Differential reconstitution of mitochondrial respiratory chain activity and plasma redox state by cysteine and ornithine in a model of cancer cachexia.
Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Biomarkers; Blood Glucose; Cachexia; Cysteine; Cystine; Electron Transport; Energy Metabolism; Fibrosarcoma; Free Radical Scavengers; Glutathione; Glycolysis; Insulin Resistance; Mice; Mice, Inbred C57BL; Mitochondria; Models, Biological; Muscle, Skeletal; Ornithine; Oxidation-Reduction; Oxidative Phosphorylation; Oxidative Stress; Plasma; Receptor, Insulin; Serum Albumin; Spermine; Sulfhydryl Compounds | 1999 |
Beneficial effects of antioxidants in diabetes: possible protection of pancreatic beta-cells against glucose toxicity.
Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Female; Insulin Resistance; Islets of Langerhans; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Vitamin E | 1999 |
Aldehyde induced hypertension in rats: prevention by N-acetyl cysteine.
Topics: Acetylcysteine; Aldehydes; Animals; Arterioles; Blood Platelets; Blood Pressure; Body Weight; Calcium; Carbohydrate Metabolism; Diet; Drinking; Eating; Energy Intake; Hyperplasia; Hypertension; Insulin Resistance; Kidney; Male; Muscle, Skeletal; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitrites; Organ Size; Pyruvaldehyde; Rats; Rats, Inbred WKY; Renal Artery; Viscera | 1998 |
Enhanced sensitivity of insulin-resistant adipocytes to vanadate is associated with oxidative stress and decreased reduction of vanadate (+5) to vanadyl (+4).
Topics: Acetylcysteine; Adipocytes; Animals; Buthionine Sulfoximine; Electron Spin Resonance Spectroscopy; Glucose; Glutathione; Insulin Resistance; Male; Oxidation-Reduction; Oxidative Stress; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Insulin; Recombinant Proteins; Vanadates | 2001 |
alpha-Lipoic acid prevents the development of glucose-induced insulin resistance in 3T3-L1 adipocytes and accelerates the decline in immunoreactive insulin during cell incubation.
Topics: 3T3 Cells; Acetylcysteine; Adipocytes; Animals; Antioxidants; Biological Transport; Culture Media, Conditioned; Dose-Response Relationship, Drug; Drug Synergism; Glucose; Insulin; Insulin Resistance; Mice; Oxidative Stress; Thioctic Acid | 2001 |