acetylcysteine has been researched along with Innate Inflammatory Response in 330 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.30) | 18.7374 |
| 1990's | 9 (2.73) | 18.2507 |
| 2000's | 75 (22.73) | 29.6817 |
| 2010's | 164 (49.70) | 24.3611 |
| 2020's | 81 (24.55) | 2.80 |
| Authors | Studies |
|---|---|
| Edwards, BS; Graves, SW; Saunders, MJ; Sklar, LA; Zhu, J | 1 |
| Collado, JA; Delgado, G; Egas, V; Méndez-Cuesta, CA; Millán, E; Muñoz, E; Ramírez-Apan, T | 1 |
| Huang, J; Huang, Y; Li, J; Ma, L; Su, L; Tang, Y; Wang, R; Wu, YH; Yang, GX; Zhang, L; Zheng, LL; Zhou, LC | 1 |
| Huang, W; Huang, Y; Ma, L; Wang, R; Yang, G | 1 |
| Kim, DW; Lee, D; Lee, H; Lim Lee, H; Sung Kang, K; Wook Lee, J; Yamabe, N | 1 |
| Sekhar, RV | 1 |
| Anna, Z; Izabela, S; Jan, M; Joanna, K; Mateusz, M; Małgorzata, ŻP; Paula, KS; Robert, ŁJ; Sara, Z | 1 |
| Aggelopoulos, S; Bitsianis, S; Chatzakis, C; Gekas, C; Gkiouliava, A; Ioannidis, O; Konstantaras, D; Kyziridis, D; Makrantonakis, A; Mantzoros, I; Miliaras, D; Parpoudi, S | 1 |
| Beloosesky, R; Ben Asher, H; Ben Zvi, D; Ginsberg, Y; Gutziet, O; Iluz, R; Khatib, N; Ross, MG; Segal, L; Weiner, Z; Zmora, O | 1 |
| Chang, G; Chen, J; Guo, X; He, J; Niu, Y; Niu, Z; Song, J; Wang, J; Wang, T; Wang, Z; Zhang, R | 1 |
| Ni, XQ; Sun, XW; Wang, XH; Wang, XJ; Xia, SJ; Zhao, RZ; Zhao, S; Zhuo, J | 1 |
| Chellan, N; Dludla, PV; Gabuza, KB; Mazibuko-Mbeje, SE; Nkambule, BB; Ntamo, Y; Nyambuya, TM; Orlando, P; Tiano, L; Ziqubu, K | 1 |
| Amar, D; Chung, MK; Desiderio, D; Fischer, GW; Isbell, JM; Jones, DR; Meyers, BF; Milne, GL; Molena, D; Park, BJ; Pedoto, A; Roistacher, N; Rusch, VW; Tan, KS; Zhang, H | 1 |
| Adir, Y; Alyan, M; Arber Raviv, S; Dor, E; Egorov, E; Farkash, S; Flikshtain, OD; Gal, Y; Harush, MY; Kaneti, G; Korach-Rechtman, H; Koren, L; Mekies, LN; Nudelman, I; Pieters, C; Saadya, A; Schroeder, A; Shainsky, J; Shklover, J; Zano, A | 1 |
| Chen, W; Cheng, M; Fan, L; Guo, Y; Liang, R; Liu, W; Ma, J; Qiu, W; Song, J; Wang, B; Wang, D; Wang, X; Yang, M; Yu, L; Zhou, M | 1 |
| Donida, B; Dos Reis, BG; Faverzani, JL; Hammerschmidt, TG; Kessler, RG; Machado, AZ; Moura, AP; Moura, DJ; Reinhardt, LS; Sebastião, FM; Vargas, CR | 1 |
| Du, J; Fang, J; Hu, Q; Li, X; Liu, B; Nie, H; Shao, X; Tai, Y; Wang, J; Yin, C | 1 |
| Hsu, JW; Jahoor, F; Kumar, P; Liu, C; Minard, CG; Muthupillai, R; Sekhar, RV; Suliburk, J; Taffet, GE | 1 |
| Andrade, KO; Barberino, RS; Campinho, DSP; Lins, TLBG; Matos, MHT; Monte, APO; Palheta Junior, RC; Silva, RLS; Smitz, JEJ | 1 |
| Huang, L; Liang, Y; Liu, X; Qiu, Z; Wang, M; Yang, S; Zhang, Y; Zhou, B | 1 |
| Cui, Y; Flaker, GC; Hao, H; Jiang, M; Liu, Q; Liu, X; Liu, Z; Xiao, Y; Zhou, S; Zhu, Q | 1 |
| Doronina, OM; Gurov, AV; Yushkina, MA | 1 |
| Abdel-Daim, MM; Ahmed, OS; Hassanein, EHM; Mohamed, WR; Sayed, AM | 1 |
| Cao, X; Gao, X; Guo, L; Guo, X; Hu, G; Huang, C; Li, G; Liu, P; Yang, F; Zhou, C; Zhuang, Y | 1 |
| Danzo, F; Pini, S; Radovanovic, D; Saad, M; Santus, P; Visconti, A; Zuffi, A | 1 |
| Feng, M; Hou, X; Ma, H; Song, L; Wang, P | 1 |
| Costa, RIDD; Fischer, JMDS; Koike, MK; Montero, EFS; Rasslan, R; Utiyama, EM | 1 |
| Abe, T; Furuyashiki, T; Kikuchi, Y; Matsui, K; Nakanishi, M; Ono, C; Oyama, N; Picotin, R; Sakai, M; Stellwagen, D; Taniguchi, M; Tomita, H; Yoshii, H; Yu, Z | 1 |
| Bakr, MH; Ezzat, GM; Kamel, AA; Mohamed, S; Nassar, AY; Nassar, GA | 1 |
| Kaya, S; Kuloğlu, T; Yalçın, T; Yiğin, A | 1 |
| Addante, A; Charbit, A; Daniltchenko, M; Drescher, M; Duerr, J; Fahy, JV; Gitlin, I; Graeber, SY; Healy, AM; Kuppe, A; Mall, MA; Orain, X; Oscarson, S; Raymond, W; Scheffler, AW | 1 |
| Abraham-Fan, RJ; Lindner, JR; López, JA; Muller, M; Ozawa, K; Packwood, W; Varlamov, O; Wu, MD; Xie, A | 1 |
| Anzueto, A; Cazzola, M; Celli, BR; Matera, MG; Page, CP; Wedzicha, JA | 1 |
| Abgharmi, BA; Charkhian, H; Ebrahimi, V; Fayyazi, F; Gholinejad, Z; Mamaghani, MM; Mosarrezaii, A; Zarrini, G | 1 |
| Bando, K; Kaji, T; Kuroishi, T; Sugawara, S; Takahashi, M | 1 |
| Elfsmark, L; Gustafson, Å; Jonasson, S; Karlsson, T | 1 |
| Aslanlar, DA; Nurullahoglu Atalik, KE; Oz, M; Vişneci, EF | 1 |
| Aldilla, VR; Das, T; Farrell, J; Glasbey, T; Kriel, E; Kumar, N; Manoharan, A; Manos, J; Moore, KH; Whiteley, G | 1 |
| Atefi, N; Baghestani, A; Goodarzi, A; Khodabandehloo, N; Mahdi, Z; Najar Nobari, N; Riahi, T; Seirafianpour, F; Talebi Taher, M; Valizadeh, R | 1 |
| Boor, PJ; Du, X; Khan, MF; Liang, Y; Sun, J; Wang, G; Wang, H | 1 |
| Burgos, ES; Charron, MJ; Manuel, CR; Munnangi, S; Pekson, R; Reznik, SE; Vuguin, PM; Williams, L | 1 |
| Alizadeh, S; Meshkani, R; Sadeghi, A; Shabani, M | 1 |
| Carlsen, H; Ghoreschi, K; Hailfinger, S; Hartl, D; Kneilling, M; Kramer, D; Mehling, R; Menendez, IG; Öz, HH; Pichler, BJ; Quintanilla-Martinez, L; Röcken, M; Schulze-Osthoff, K; Schwenck, J; Thaiss, WM | 1 |
| Guo, L; Huang, J; Xiong, T; Zhang, Z; Zheng, R | 1 |
| Bagio, E; Barichello, T; Bonfante, SRSA; de Carli, RJ; de Oliveira Junior, AN; de Oliveira, MP; Della Giustina, A; Dos Santos, TM; Engel, NA; Goldim, MPS; Joaquim, L; Kanis, LA; Metzker, KLL; Muttini, S; Novochadlo, M; Petronilho, F; Rezin, GT; Tenfen, L | 1 |
| Albertini, G; Bentea, E; Deneyer, L; Massie, A | 1 |
| Dağli, F; Güntürk, I; Köse, SK; Yay, AH; Yazici, C; Yücel, B | 1 |
| Chen, Q; Chen, YH; Li, J; Li, Z; Lin, L; Shen, E; Wan, X; Xia, M; Yan, D; Zhan, W; Zhang, G; Zhang, Q | 1 |
| Cai, H; Hu, K; Li, L; Li, M; Ren, J; Su, D; Wu, X; Zhai, J; Zhang, M | 1 |
| Elseady, WS; Ibrahim, MA; Keshk, WA; Shalaby, SM; Zalat, ZA | 1 |
| Colle, I; Debacker, PJ; Devisscher, L; Geerts, A; Lefere, S; Raevens, S; Van Campenhout, S; Van Vlierberghe, H; Verhelst, X | 1 |
| Chen, Y; Dong, Y; Feng, X; Qu, C; Wang, T; Wang, Y; Wo, X; Wu, X; Xu, W; Zhang, J; Zhao, S; Zhao, W; Zhong, Z | 1 |
| Britti, D; Cordaro, M; Crupi, R; Cuzzocrea, S; Di Paola, R; Gugliandolo, E; Impellizzeri, D; Siracusa, R | 1 |
| Alnahdi, A; John, A; Raza, H | 1 |
| Hong, J; Jang, AS; Lee, PH | 1 |
| Bar-Klein, G; Friedman, A; Hameed, MQ; Jozwiak, S; Kaminski, RM; Klein, P; Klitgaard, H; Koepp, M; Löscher, W; Prince, DA; Rotenberg, A; Twyman, R; Vezzani, A; Wong, M | 1 |
| Dai, X; Kong, L; Li, Z; Sun, Y; Wang, Q; Wang, X; Zhong, W; Zhou, H | 1 |
| Charron, MJ; Chaurasia, B; Du, XQ; Katz, EB; Reznik, SE; Saghatelian, A; Seki, Y; Summers, SA; Vuguin, PM; Williams, L | 1 |
| Andreou, A; Filippou, D; Sipsas, N; Trantza, S; Tsiodras, S | 1 |
| Corn, J; Poe, FL | 1 |
| Pal, A; Pal, S; Rao, GN | 1 |
| Berk, M; Bortolasci, CC; Cotton, SM; Dean, OM; Dodd, S; Dowling, N; Gray, L; Malhi, GS; Mohebbi, M; Ng, CH; Sarris, J; Turner, A; Voigt, C; Walder, K | 1 |
| Duan, Q; Kang, T; Liu, M; Naqvi, S; Wang, Z; Xiao, S; Zhang, F; Zhang, G; Zheng, Y | 1 |
| Goldenberg, R; Ibrahim, H; Kon, Z; Lewis, T; Perl, A; Smith, D; Staniloae, C; Williams, M; Yarta, K | 1 |
| Muniroh, M | 1 |
| Faghfouri, AH; Faghfuri, E; Kord-Varkaneh, H; Ostadrahimi, A; Radkhah, N; Tan, SC; Tavakoli-Rouzbehani, OM; Zarezadeh, M | 1 |
| Abdallah, FR; Atteia, HH; Elswefy, SE; Hasan, RA; Wahba, AS | 1 |
| Angelillo, IF; Barone, B; Boccellino, M; Boffo, S; Crocetto, F; Di Domenico, M; Di Zazzo, E; Galasso, G; Imbimbo, C; Quagliuolo, L; Sciarra, A; Settembre, G | 1 |
| Accardi, M; Baietti, MG; Fadin, M; Fratter, A; Nicoletti, MC; Pellizzato, M | 1 |
| Jobe, AH | 1 |
| Ali, I; Li, C; Li, L; Wang, G; Wang, Y | 1 |
| Kaufman, G; Skrtic, D | 1 |
| Cai, L; Chen, XX; Keller, BB; Lin, Q; Tan, Y; Wang, X; Yu, HT; Zheng, Y | 1 |
| Beloosesky, R; Boulos, S; Fainaru, O; Ginsberg, Y; Gutzeit, O; Khatib, N; Millo, Z; Ross, MG; Segal, L; Weiner, Z; Zmora, O | 1 |
| Du, X; Guo, LL; Liu, L; Liu, YS; Tian, F; Wen, T; Xiang, QY; Xu, J; Zhu, LY | 1 |
| Alcock, E; Bhan, A; Dew, T; Dworakowski, R; MacCarthy, P; Monaghan, M; Navaratnarajah, A; Shah, AM; Wendler, O | 1 |
| Chattipakorn, S; Chuveera, P; Dewi, A; Ittichaicharoen, J; Jariyamana, N; Leelapornpisid, W; Srisuwan, T | 1 |
| Büyük, B; Coşkun, Ö; Öztopuz, Ö | 1 |
| Chattipakorn, S; Chompu-Inwai, P; Chuenjitkuntaworn, B; Chuveera, P; Ittichaicharoen, J; Srisuwan, T; Vaseenon, S; Weekate, K | 1 |
| Bastin, AR; Doustimotlagh, AH; Nazari-Robati, M; Sadeghi, A; Sadeghi, H | 1 |
| Kim, H; Lee, J; Lim, JW | 1 |
| Alizadeh, B; Arasteh, A; Ranji, N; Salehzadeh, A | 1 |
| Chacko, S; Hsu, JW; Jahoor, F; Kumar, P; Liu, C; Minard, C; Sekhar, RV | 1 |
| Cao, L; Cen, X; Chen, W; Cheng, M; He, H; Ma, J; Mu, G; Qiu, W; Wang, B; Wang, D; Wang, X; Xiao, L; Yang, S; Ye, Z; Yuan, J; Zhou, M; Zhou, Y; Zhu, C | 1 |
| An, L; Li, G; Qu, Y; Wang, J; Ye, W; Zhang, Q; Zhao, X; Zhao, Z; Zheng, D | 1 |
| Chen, J; Fan, F; Guo, M; Jiang, C; Long, Y; Tang, S; Wang, Y; Xu, Y | 1 |
| Abo-Youssef, AM; Hassan, MIA; Hemeida, RAM; Osman, AT; Sharkawi, SMZ | 1 |
| Hu, Z; Liu, X; Zhou, H | 1 |
| Gan, X; He, Y; Yu, H; Zhang, L; Zhu, J; Zhu, Z | 1 |
| Chen, M; Feng, J; He, J; Lan, J; Liang, W; Mo, L; Song, M; Zheng, D | 1 |
| Allenbach, Y; Alsaleh, G; Benveniste, O; Boyer, O; Charles, AL; Echaniz-Laguna, A; Geny, B; Gottenberg, JE; Grelet, E; Lannes, B; Laporte, J; Laverny, G; Lonsdorfer, E; Maurier, F; Metzger, D; Meyer, A; Nicot, AS; Sibilia, J; Singh, F; Ueberschlag, V; Zoll, J | 1 |
| Bergold, PJ; Grin'kina, NM; Haber, M; Hartman, I; Ho, J; Irizarry, R; James, J; Kim, J; Nikulina, E; Ramadani, A; Sangobowale, M | 1 |
| Ahn, G; Cho, SH; Eom, CY; Heo, SJ; Jeon, YJ; Jeong, MS; Kim, KN; Kim, SY; Ko, EY; Kwon, SH; Lee, KP; Lee, W | 1 |
| Baccarelli, AA; Bartolucci, GB; Byun, HM; Carrieri, M; Guo, L; Jiménez-Garza, O; Zhong, J | 1 |
| Bakr, AG; Khalifa, MMA; Osman, AT | 1 |
| Akhtar, F; Asmis, R; Catano, G; Kharbanda, K; Maffi, SK; Montalvo, M; Rouse, CA; Ullevig, SL | 1 |
| Ajith, TA; Antonawich, F; Janardhanan, KK; Veena, RK | 1 |
| Alipour, A; Azizi, S; Emami Zeydi, A; Habibi, MR; Habibi, V; Hasanzadeh Kiabi, F; Sohrabi, FB; Soleimani, A | 1 |
| Constantino, L; da Silva, LA; Dal-Pizzol, F; Dall'Igna, DM; de Medeiros, WA; Dos Santos Cardoso, J; Manfredini, A; Michels, M; Ritter, C; Scaini, G; Streck, EL; Vuolo, F | 1 |
| Cai, Z; Chen, Y; Dong, C; Dong, W; Geng, H; Li, R; Yang, Z; Zhang, Y | 1 |
| Bae, H; Cheng, WN; Han, SG; Hong, K; Jeong, CH; Seo, HG | 1 |
| Colpo, GD; Dantzer, R; Leboyer, M; Teixeira, AL; Trivedi, MH | 1 |
| Ghanei, M; Hashjin, MM; Panahi, Y; Rezaee, R; Sahebkar, A | 1 |
| Al-Khalidi, S; Desai, R; Gao, X; Lampraki, EM; Qureshi, MA; Wilson, JB | 1 |
| Bedreag, OH; Bratu, LM; Bratu, T; Cradigati, CA; Dinu, A; Papurica, M; Popovici, SE; Rogobete, AF; Sandesc, D; Sandesc, M; Sarandan, M; Stan, AT | 1 |
| Li, YH; Wan, RJ | 1 |
| Beloosesky, R; Efrat, S; Ginsberg, Y; Khatib, N; Mordechai, H; Ross, MG; Sharabi, H; Tamar, BK; Weiner, Z | 1 |
| Pan, X; Peng, C; Rao, C; Wu, X; Yan, D; Yan, H | 1 |
| Choi, SE; Koh, HC; Park, YS | 1 |
| Cieslik, KA; Entman, ML; Granillo, A; Gupte, AA; Hamilton, DJ; Heredia, CP; Li, S; Medrano, G; Reddy, A; Reineke, E; Sekhar, RV; Taffet, GE; Zhang, A | 1 |
| Hu, ZQ; Li, YJ; Li, ZG; Song, SD; Tang, HF; Wang, XF; Yan, CG; Zhang, ZW | 1 |
| Ko, JL; Lai, YY; Liou, GG; Tsai, MS; Tsou, HK; Wang, SH; Wang, YH | 1 |
| Calzetta, L; Cazzola, M; Facciolo, F; Matera, MG; Rinaldi, B; Rogliani, P | 1 |
| di Michele, F; Niolu, C; Siracusano, A; Talamo, A | 1 |
| Chen, J; Jiao, Y; Liu, H; Pei, Y; Tay, FR; Yang, Y | 1 |
| Li, Y; Liu, T; Liu, Y; Shi, X; Wang, H; Wang, Y; Xia, T | 1 |
| Gu, Y; Huang, LM; Li, G | 1 |
| Aldridge, K; Bowden, A; Dosanjh, D; Foronjy, R; Grudzinska, FS; Lewis, KE; Lugg, ST; Mahida, RY; Naidu, B; Parekh, D; Sapey, E; Scott, A; Thickett, DR | 1 |
| Bosker, FJ; Li, J; Schoevers, RA; Yang, C | 1 |
| Ataei, S; Basiri, Z; Hashemi, G; Kheiripour, N; Mehrpooya, M; Mirjalili, M; Ranjbar, A; Shahdoust, M; Tahamoli-Roudsari, A | 1 |
| Ahmad, SF; Al-Harbi, MM; Al-Harbi, NO; AlAsmari, AF; Alfardan, AS; Nadeem, A | 1 |
| Coitinho, AS; de Coelho, DM; Deon, M; Guerreiro, GB; Jacques, CE; Jardim, LB; Marchetti, DP; Mescka, CP; Moura, DJ; Poletto, F; Steffens, L; Vargas, CR; Viario, AG | 1 |
| Ju, Y; Ma, Y; Wang, T; Zhang, Q | 1 |
| Feng, J; Ge, CX; Gu, TT; Hu, LF; Huang, P; Li, Q; Lou, DS; Qin, YT; Tan, J; Xu, MX | 1 |
| Fernandes, J; Gupta, GL | 1 |
| Agnes, JP; Delgobo, M; Dos Santos, VW; Gonçalves, RM; Parisotto, EB; Zamoner, A; Zanotto-Filho, A | 1 |
| Cao, MM; Jiang, W; Li, YB; Liu, GD; Su, Y; Wang, J; Zhu, LB | 1 |
| Huang, S; Li, Y; Liang, X; Liu, Y; Wang, K; Wei, H; You, J; Zhang, Y | 1 |
| Choo, MS; Heo, J; Ju, H; Kim, S; Lee, S; Lim, J; Ryu, CM; Shin, DM; Shin, JH; Yu, HY | 1 |
| Apaijai, N; Arinno, A; Chattipakorn, N; Chattipakorn, SC; Chunchai, T; Keawtep, P; Pratchayasakul, W; Prus, D; Saiyasit, N | 1 |
| Cirilli, I; Dludla, PV; Louw, J; Marcheggiani, F; Mazibuko-Mbeje, SE; Mxinwa, V; Nkambule, BB; Nyambuya, TM; Tiano, L | 1 |
| Beloosesky, R; Ginsberg, Y; Itskovitz-Eldor, J; Khatib, N; Maravi, N; Ross, MG; Weiner, Z | 1 |
| Agilli, M; Alp, BF; Altayli, E; Aydin, FN; Aydin, I; Cayci, T; Cermik, H; Ozkan, E; Taslipinar, MY; Toygar, M; Ucar, F | 1 |
| Amato, L; Bernardini, G; Braconi, D; Chellini, F; Collodel, G; Frediani, B; Geminiani, M; Ghezzi, L; Millucci, L; Moretti, E; Santucci, A; Spreafico, A | 1 |
| Athanasopoulos, S; Chatzinikolaou, A; Fatouros, IG; Hawley, JA; Jamurtas, AZ; Karagounis, LG; Mandalidis, D; Michailidis, Y; Papassotiriou, I; Russell, AP; Spengos, K; Stefanetti, RJ; Terzis, G; Tsoukas, D | 1 |
| Jiang, H; Yin, G; Zhang, C; Zhang, H | 1 |
| Jiang, S; Ni, SZ; Xia, J; Zhao, Y; Zhou, XL; Zhu, YQ | 1 |
| Baba, SP; Barski, OA; Bhatnagar, A; Cai, J; Conklin, DJ; Hoetker, JD; Klein, JB; Merchant, M | 1 |
| Abdel Baki, SG; Bergold, PJ; Dash, P; Ershova, A; Grill, RJ; Grin'kina, NM; Haber, M; Irizarry, R; Orsi, S | 1 |
| Chen, GX; Chen, JT; Li, W; Qin, S; Wu, Q; Yao, L; Ye, WB; Yuan, K; Zeng, JH; Zheng, S; Zhong, ZM | 1 |
| Chen, CS; Cho, HJ; Hseu, YC; Lin, CW; Lin, SW; Lu, FJ; Senthil Kumar, KJ; Shen, PC; Yang, HL | 1 |
| Akaike, T; Aoi, J; Endo, M; Fukushima, S; Hirakawa, S; Horiguchi, H; Ihn, H; Jinnin, M; Kadomatsu, T; Masuda, T; Miyata, K; Odagiri, H; Ogata, A; Oike, Y; Sawa, T | 1 |
| Ponticelli, C | 1 |
| Chen, G; Chen, J; Chen, P; Feng, J; Guo, R; Hua, X; Mo, L; Wu, K; Xu, W; Zheng, D | 1 |
| Arab, HH; Maghrabi, IA; Omar, HA; Salama, SA; Snapka, RM | 1 |
| Alvarez, FJ; Barreiro, E; Casadevall, C; Domínguez-Álvarez, M; Gáldiz, JB; Gea, J; Sabaté-Brescó, M; Vilà-Ubach, M | 1 |
| Dieleman, JM; Jacob, KA; Kluin, J; Nathoe, HM; van Dijk, D; van Osch, D | 1 |
| Akcay, S; Ceyhan, BM; Dogan, A; Erdogan, D; Icli, A; Okutan, H; Ozaydin, M; Peker, O; Sutcu, R; Uysal, BA; Varol, E; Yucel, H | 1 |
| Ireland, DJ; Keelan, JA; Kemp, MW; Newnham, JP; Payne, MS; Stinson, LF; Stock, SJ | 1 |
| Bentley, DJ; Coutts, AJ; Dascombe, B; Slattery, KM; Wallace, LK | 1 |
| Cingi, C; Dündar, R; İlknur, AE; İnan, S; Katılmış, H; Muluk, NB | 1 |
| Abdelmoula, J; Ahmed, MB; Annabi, A; Belhadjhmida, N; Bouzid, K; Dhouib, IB; El Fazaa, S; Gharbi, N; Lamine, AJ; Lasram, MM | 1 |
| Chayanupatkul, M; Liangpunsakul, S | 1 |
| Heintz, NH; MacPherson, MB; Mossman, BT; Shukla, A; Spiess, P; Thompson, JK; Westbom, CM | 1 |
| Fu, J; Ji, K; Li, G; Luan, T; Zang, B; Zhao, Y | 1 |
| Chang, E; Cox, T; Fanning, D; Garner, S; Jenkins, DD; Wiest, DB | 1 |
| Chen, G; Guan, J; Jiang, G; Lin, S; Xu, Z | 1 |
| Antony, V; Chatfield, B; Clancy, J; Conrad, C; Davies, Z; Dunn, C; Egan, ME; Goss, CH; Herzenberg, LA; Lymp, J; Michelson, P; Moss, RB; Nichols, D; Quittell, L; Rubenstein, RC; Spahr, J; Thompson, V; Tirouvanziam, R; Vender, R | 1 |
| Choi, S; Lee, JH; Lee, S; Min, BS; Nguyen, VT; Ryoo, S; Tae, N | 1 |
| Bollineli, RC; Marques, MJ; Minatel, E; Mizobuti, DS; Moraes, LH; Silveira, Ldos R | 1 |
| Andrade, CF; da Rosa, DP; e Silva, MB; Fiori, CZ; Forgiarini, LF; Marroni, NP; Martinez, D | 1 |
| Ciofu, O; Høiby, N; Jensen, PØ; Johansen, HK; Kræmer, D; Lykkesfeldt, J; Poulsen, HE; Pressler, T; Qvist, T; Skov, M | 1 |
| Avcı, B; Çavun, S; Savcı, V; Şentürk, T; Serdar, Z; Yermezler, A | 1 |
| Adamski, J; Aichler, M; Algül, H; Artati, A; Demir, IE; Diakopoulos, KN; Erkan, M; Fischer, R; Halangk, W; Kabiri, Y; Lesina, M; Mantzoros, CS; Pilsak, C; Römisch-Margl, W; Schild, L; Schmid, RM; Song, L; Steiner, JM; Walch, A; Wartmann, T; Witt, H; Wörmann, S; Zischka, H | 1 |
| Chung, KH; Kim, HR; Shin, DY | 1 |
| Feltis, BN; Lopata, AL; Saptarshi, SR; Wright, PF | 1 |
| Fujii, H; Hai, H; Kawada, N; Kubo, S; Matsumoto, Y; Morita, T; Motoyama, H; Suoh, M; Takemura, S; Tamori, A; Thuy, le TT; Thuy, TT; Urahara, Y; Yoshizato, K | 1 |
| Chen, W; Lu, H; Qu, J; Reinach, PS; Ren, Y; Xiao, B; Zheng, Q; Zhu, Y | 1 |
| Jiménez-Vélez, BD; Ortiz-Martínez, MG; Rodríguez-Cotto, RI | 1 |
| Chen, N; Isobe, K; Ito, S; Liu, L; Nishio, N; Sun, Y; Tanaka, Y | 1 |
| Fujita, T; Kajiya, M; Kurihara, H; Matsuda, S; Ouhara, K; Shiba, H; Yoshimoto, T | 1 |
| Bent, S; Hendren, RL | 1 |
| Dal-Bó, AG; Dal-Pizzol, F; De Costa, L; Effting, PS; Ferreira, GK; Frizon, TE; Paula, MM; Petronilho, F; Pinho, RA; Santos, GP; Silveira, PC; Vuolo, F | 1 |
| Agostinis, C; Bulla, R; De Leo, R; De Seta, F; Zauli, G; Zorzet, S | 1 |
| Cao, S; Huang, C; Yuan, L | 1 |
| Brown, EL; Chatzinikolaou, A; Della Gatta, PA; Draganidis, D; Fatouros, IG; Jamurtas, AZ; Karagounis, LG; Mandalidis, D; Mastorakos, G; Methenitis, S; Michailidis, Y; Russell, AP; Spengos, K; Terzis, G; Wright, CR | 1 |
| Chehuen, M; da Silva, ND; de Oliveira, EM; Fernandes, T; Forjaz, CL; Han, SW; Martin, PK; Mota, GF; Roseguini, BT; Wolosker, N | 1 |
| Alonso-Varona, A; Azcoitia, I; Bastida, F; Castro, B; del Olmo, M; Palomares, T; Soldevilla, JJ | 1 |
| Alfonso, H; Burcham, P; Ching, S; Croft, K; de Klerk, N; Franklin, P; Joyce, D; Musk, AB; Olsen, N; Reid, A | 1 |
| Jeong, KY; Kim, CR; Kim, HP; Kim, TY; Yi, MH; Yong, TS | 1 |
| Chao, J; Chao, L; Chen, CW; Huang, YW; Lin, CF; Lin, WC; Lin, YS | 1 |
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| de Andrade, KQ; de Araújo, OR; de Farias Santos, JC; dos Santos, JM; Goulart, MO; Moura, FA | 1 |
| Barkes, B; Canono, B; Day, B; Gillespie, M; Hamzeh, N; Huang, J; Li, L; Maier, L | 1 |
| Chen, G; Feng, H; Gao, C; Gou, F; Gu, J; Huang, W; Liu, S; Long, Y; Lü, S; Luo, Q; Xu, Y; Yang, M; Zhou, X | 1 |
| Abdelzaher, LA; Hattori, Y; Imaizumi, T; Suzuki, T; Takashina, M; Tomita, K | 1 |
| Chen, F; Chen, J; Chu, X; Huang, J; Huang, S; Li, N; Sun, S; Zha, L; Zhang, Y | 1 |
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| Fang, F; Huang, D; Xu, F | 1 |
| Deng, Y; Lu, X; Zhao, L | 1 |
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| Ahmad, SF; Al-Harbi, MM; Al-Harbi, NO; Alotaibi, MR; AlSaad, AM; Ansari, MA; Nadeem, A | 1 |
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| Albano, E; Badger, TM; Baumgardner, JN; Hennings, L; Ronis, MJ; Shankar, K | 1 |
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| Alexandrou, A; Giakoustidis, AE; Katsargyris, A; Klonaris, C; Theocharis, S; Vasileiou, I | 1 |
| Beloosesky, R; Boles, J; Itskovitz-Eldor, J; Khativ, N; Mandel, R; Maravi, N; Ross, MG; Weiner, Z | 1 |
| Akamatsu, K; Hirano, T; Ichikawa, T; Ichinose, M; Kanda, M; Koarai, A; Matsunaga, K; Minakata, Y; Sugiura, H; Tanaka, R; Yanagisawa, S | 1 |
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| Anderson-Hunt, M; Berk, M; Bush, AI; Copolov, DL; Dean, OM; Jeavons, S; Kohlmann, K; Magalhães, PV; Malhi, GS; Schapkaitz, I; Weisinger, D | 1 |
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| Chen, X; Ding, B; Hou, Y; Li, J; Qiu, Y; Wang, L; Wu, G; Yang, Z; Yi, D | 1 |
| Castaño, A; García-Cuervo, L; Gavilán, E; Gavilán, MP; Gutiérrez, A; Pintado, C; Ríos, RM; Ruano, D; Vitorica, J | 1 |
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| de Senzi Moraes Pinto, R; Ferretti, R; Marques, MJ; Minatel, E; Moraes, LH; Neto, HS | 1 |
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| Karalija, A; Kingham, PJ; Novikov, LN; Novikova, LN; Wiberg, M | 1 |
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| Chen, S; Fang, X; Jin, Y; Li, H; Wu, S; Xie, G | 1 |
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| Gao, L; Guo, NN; Kang, JR; Li, F; Lu, JY; Sun, JZ; Wang, HW; Yang, W; Zhang, W | 1 |
| Arreola, JL; Barrios, R; Cisneros-Lira, J; Gaxiola, M; Kala, SV; Lieberman, MW; Pardo, A; Ramírez, R; Ruiz, V; Selman, M | 1 |
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| Santangelo, F | 1 |
| Adams, J; Berti, R; Dave, JR; Elliott, PJ; Moffett, JR; Tortella, FC; Velarde, LC; Williams, AJ; Yao, C | 1 |
| Atik, U; Aytacoglu, B; Cinel, I; Dikmengil, M; Gul, A; Karaca, K; Kocak, Z; Oral, U; Sucu, N; Tamer, L; Unlu, A | 1 |
| Adams, J; Berti, R; Dave, JR; Elliot, PJ; Tortella, FC; Williams, AJ | 1 |
| Gilg, AG; Giri, S; Jatana, M; Khan, M; Sekhon, B; Sekhon, C; Singh, AK; Singh, I | 1 |
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| Khan, M; Pannu, R; Singh, AK; Singh, I; Won, JS | 1 |
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| Andrades, M; Dal-Pizzol, F; Martins, MR; Menna-Barreto, S; Moreira, JC; Quevedo, J; Reinke, A; Ritter, C; Rocha, J | 1 |
| Barzilai, N; Berg, AH; Brownlee, M; Combs, TP; Du, X; Fantus, IG; Giacca, A; Hawkins, M; Iyengar, P; Lam, TK; Li, W; Lin, Y; Rajala, MW; Rhodes, CJ; Rollman, B; Scherer, PE | 1 |
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| Chang, JW; Kim, CS; Kim, SB; Lee, SK; Park, JS; Park, SK | 1 |
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| Dal-Pizzol, F; F Moreira, JC; Luiz Streck, E; Pinho, RA; Silva, LA; Silveira, PC | 1 |
| Bitter-Suermann, S; Kanniess, F; Magnussen, H; Watz, H | 1 |
| Kolbert, C; Morrison, DC; Papasian, C; Qureshi, AA; Qureshi, N; Raghavakaimal, S; Reis, J; Shen, J; Vogel, SN | 1 |
| Gao, JJ; Morrison, DC; Papasian, C; Qureshi, N; Shen, J; Tan, X; Vogel, SN; Zhang, G | 1 |
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37 review(s) available for acetylcysteine and Innate Inflammatory Response
| Article | Year |
|---|---|
GlyNAC Supplementation Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Aging Hallmarks, Metabolic Defects, Muscle Strength, Cognitive Decline, and Body Composition: Implications for Healthy Aging.
Topics: Acetylcysteine; Aged; Animals; Body Composition; Cognitive Dysfunction; Dietary Supplements; Glutathione; Healthy Aging; Humans; Inflammation; Mice; Mitochondria; Muscle Strength; Oxidative Stress; Randomized Controlled Trials as Topic | 2021 |
Clinical use of N-acetyl cysteine during liver transplantation: Implications of oxidative stress and inflammation as therapeutic targets.
Topics: Acetylcysteine; Humans; Inflammation; Liver Failure; Liver Transplantation; Oxidative Stress; Randomized Controlled Trials as Topic; Reperfusion Injury | 2022 |
The role of inflammation in cadmium nephrotoxicity: NF-κB comes into view.
Topics: Acetylcysteine; Cadmium; Cytochalasin D; Cytokines; Humans; Inflammation; Kidney Diseases; NF-kappa B; Polysaccharides; Sildenafil Citrate; Telmisartan | 2022 |
Use of thiols and implications for the use of inhaled corticosteroids in the presence of oxidative stress in COPD.
Topics: Acetylcysteine; Adrenal Cortex Hormones; Antioxidants; Expectorants; Humans; Inflammation; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Sulfhydryl Compounds | 2023 |
Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy?
Topics: Acetylcysteine; Animals; Anticonvulsants; Antioxidants; Atorvastatin; Brain Injuries, Traumatic; Ceftriaxone; Dibenzazepines; Drug Repositioning; Epilepsy; Epilepsy, Post-Traumatic; Erythropoietin; Fingolimod Hydrochloride; GABA Agents; Gabapentin; Humans; Immunologic Factors; Inflammation; Interleukin 1 Receptor Antagonist Protein; Isoflurane; Levetiracetam; Losartan; Neuroprotective Agents; Oxidative Stress; Pregabalin; Pyrrolidinones; Sirolimus; Stroke; Topiramate; Translational Research, Biomedical; Vigabatrin | 2020 |
COVID-19: The Potential Role of Copper and N-acetylcysteine (NAC) in a Combination of Candidate Antiviral Treatments Against SARS-CoV-2.
Topics: Acetylcysteine; Adenosine Monophosphate; Adjuvants, Immunologic; Alanine; Anti-Inflammatory Agents; Antiviral Agents; Autophagy; Betacoronavirus; Colchicine; Copper; Coronavirus Infections; COVID-19; Cytidine; Drug Synergism; Drug Therapy, Combination; Humans; Hydroxylamines; Inflammation; Nitric Oxide; Pandemics; Pneumonia, Viral; Prodrugs; Ribonucleosides; SARS-CoV-2; Virus Internalization; Virus Replication | 2020 |
Methylmercury-induced pro-inflammatory cytokines activation and its preventive strategy using anti-inflammation N-acetyl-l-cysteine: a mini-review.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Brain; Cytokines; Humans; Inflammation; Methylmercury Compounds; Mice; Rats | 2020 |
The effects of N-acetylcysteine on inflammatory and oxidative stress biomarkers: A systematic review and meta-analysis of controlled clinical trials.
Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Cytokines; Female; Humans; Inflammation; Inflammation Mediators; Male; Middle Aged; Oxidative Stress; Randomized Controlled Trials as Topic; Young Adult | 2020 |
The Crosstalk between Prostate Cancer and Microbiota Inflammation: Nutraceutical Products Are Useful to Balance This Interplay?
Topics: Acetylcysteine; Carnitine; Chronic Disease; Dietary Supplements; Disease Progression; Fatty Acids, Unsaturated; Gastrointestinal Microbiome; Humans; Inflammation; Male; Monoterpenes; Polyphenols; Prostate; Prostatic Neoplasms | 2020 |
Immune-based strategies for mood disorders: facts and challenges.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Bipolar Disorder; Cytokines; Depressive Disorder, Major; Exercise Therapy; Fatty Acids, Unsaturated; Humans; Inflammation; Mesenchymal Stem Cell Transplantation; Mood Disorders; Neuroimmunomodulation; Probiotics | 2018 |
Potential Utility of N-acetylcysteine for Treating Mustard Lung.
Topics: Acetylcysteine; Apoptosis; Chemical Warfare Agents; Humans; Inflammation; Lung; Lung Diseases; Mustard Gas; Oxidative Stress | 2017 |
N-Acetyl Cysteine and Vitamin D Supplementation in Treatment Resistant Obsessive-compulsive Disorder Patients: A General Review.
Topics: Acetylcysteine; Animals; Dietary Supplements; Humans; Inflammation; Neuroprotective Agents; Obsessive-Compulsive Disorder; Vitamin D | 2018 |
Biological Activities and Potential Oral Applications of N-Acetylcysteine: Progress and Prospects.
Topics: Acetylcysteine; Administration, Oral; Glutathione; Humans; Inflammation | 2018 |
The beneficial effects of N-acetyl cysteine (NAC) against obesity associated complications: A systematic review of pre-clinical studies.
Topics: Acetylcysteine; Animals; Humans; Inflammation; Obesity; Oxidative Stress; Transcription Factors | 2019 |
Inflammation in new-onset atrial fibrillation after cardiac surgery: a systematic review.
Topics: Acetylcysteine; Anti-Inflammatory Agents; Antioxidants; Atrial Fibrillation; Biomarkers; Cardiac Surgical Procedures; Colchicine; Epidemiologic Methods; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Postoperative Complications; Steroids; Vitamins | 2014 |
Alcoholic hepatitis: a comprehensive review of pathogenesis and treatment.
Topics: Acetylcysteine; Adrenal Cortex Hormones; Alcoholism; End Stage Liver Disease; Enteral Nutrition; Hepatitis, Alcoholic; Humans; Immunity, Innate; Inflammation; Liver Transplantation; Pentoxifylline; Propylthiouracil; S-Adenosylmethionine; Treatment Outcome | 2014 |
Complementary and alternative treatments for autism part 1: evidence-supported treatments.
Topics: Acetylcysteine; Animals; Antipsychotic Agents; Aripiprazole; Autistic Disorder; Complementary Therapies; Disease Models, Animal; Evidence-Based Medicine; Free Radical Scavengers; Gastrointestinal Tract; Humans; Inflammation; Mice; Oxidative Stress; Randomized Controlled Trials as Topic; Risperidone; United States; United States Food and Drug Administration; Vitamin B 12 | 2015 |
The Role of Reactive Oxygen Species in Myelofibrosis and Related Neoplasms.
Topics: Acetylcysteine; Animals; Antioxidants; Disease Progression; Hepatitis C; Humans; Inflammation; Mice; Myeloproliferative Disorders; Neoplasms; Oxidative Stress; Primary Myelofibrosis; Reactive Oxygen Species; Signal Transduction | 2015 |
Oxidative Stress and Inflammation in Hepatic Diseases: Therapeutic Possibilities of N-Acetylcysteine.
Topics: Acetylcysteine; Animals; Biomarkers; Humans; Inflammation; Liver Diseases; Models, Biological; Oxidative Stress | 2015 |
Oxidative stress in the pathogenesis of atherothrombosis associated with anti-phospholipid syndrome and systemic lupus erythematosus: new therapeutic approaches.
Topics: Acetylcysteine; Anticoagulants; Antioxidants; Antiphospholipid Syndrome; Atherosclerosis; Autoantibodies; beta 2-Glycoprotein I; Coagulants; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Lupus Erythematosus, Systemic; Mitochondrial Diseases; Oxidative Stress; Reactive Oxygen Species; Recurrence; Thrombosis; Ubiquinone | 2016 |
Toll-like receptors in liver ischemia reperfusion injury: a novel target for therapeutic modulation?
Topics: Acetylcysteine; Adaptor Proteins, Vesicular Transport; Animals; Communicable Diseases; Dendritic Cells; Drosophila Proteins; Endothelial Cells; Epithelial Cells; Hepatic Stellate Cells; Hepatocytes; Humans; Inflammation; Kupffer Cells; Ligands; Liver; Liver Transplantation; Mammals; Mice; Myeloid Differentiation Factor 88; Reperfusion Injury; Toll-Like Receptors | 2009 |
Oxidative stress, inflammation and carcinogenesis are controlled through the pentose phosphate pathway by transaldolase.
Topics: Acetylcysteine; Animals; Autoimmunity; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Fatty Liver; Glucose; Humans; Infertility, Male; Inflammation; Male; Mitochondria; Oxidative Stress; Pentose Phosphate Pathway; Sperm Motility; Transaldolase | 2011 |
N-Acetylcysteine mucolysis in the management of chronic obstructive pulmonary disease.
Topics: Acetylcysteine; Expectorants; Gene Expression Regulation; Humans; Inflammation; Mucins; Mucus; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Reactive Oxygen Species; Signal Transduction | 2012 |
Proteasome inhibition: a new anti-inflammatory strategy.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Arthritis, Rheumatoid; Asthma; Boronic Acids; Bortezomib; Clinical Trials as Topic; Cysteine Endopeptidases; Disease Models, Animal; Humans; Inflammation; Lysine; Models, Biological; Models, Chemical; Multienzyme Complexes; Multiple Sclerosis; Neoplasms; NF-kappa B; Peptides; Protease Inhibitors; Proteasome Endopeptidase Complex; Psoriasis; Pyrazines; Reperfusion Injury | 2003 |
MLN-519. Millennium/PAION.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Cysteine Endopeptidases; Enzyme Inhibitors; Humans; Inflammation; Multienzyme Complexes; Myocardial Infarction; Neuroprotective Agents; Proteasome Endopeptidase Complex; Stroke; Ubiquitin | 2003 |
Intracellular thiol concentration modulating inflammatory response: influence on the regulation of cell functions through cysteine prodrug approach.
Topics: Acetylcysteine; Acute-Phase Proteins; Animals; Cell Cycle; Cysteine; Cytokines; Glutathione; Humans; Inflammation; Prodrugs; Sulfhydryl Compounds; Thiazoles | 2003 |
[Oxidative stress in bronchopulmonary disease: contribution of N-acetylcysteine (NAC)].
Topics: Acetylcysteine; Glutathione; Humans; Inflammation; Lung Diseases; Oxidative Stress | 2005 |
The proteasome: a central regulator of inflammation and macrophage function.
Topics: Acetylcysteine; Aging; Animals; Atherosclerosis; Cholesterol; Humans; Inflammation; Lipopolysaccharides; Macrophages; Mice; Neurodegenerative Diseases; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Shock, Hemorrhagic; Signal Transduction; Toll-Like Receptor 2 | 2005 |
Molecular mechanisms of aging-associated inflammation.
Topics: Acetylcysteine; Aging; Animals; Anti-Inflammatory Agents; Cell Line, Tumor; Cellular Senescence; Chemokines; Cytokines; Enzyme Inhibitors; Exoribonucleases; Free Radicals; Humans; Inflammation; Neurodegenerative Diseases; NF-kappa B; Reactive Oxygen Species | 2006 |
[Pharmacological treatment of COPD and future of anti-inflammatory therapy].
Topics: Acetylcysteine; Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antibodies, Monoclonal; Bronchodilator Agents; Carboxylic Acids; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Dyspnea; Expectorants; Forced Expiratory Volume; Forecasting; Humans; Inflammation; Infliximab; Lung; Macrolides; Nitriles; Phosphodiesterase Inhibitors; Pilot Projects; Pulmonary Disease, Chronic Obstructive; Randomized Controlled Trials as Topic; Research; Respiratory Function Tests; Simvastatin; Smoking Cessation; Tetracycline; Theophylline; Tumor Necrosis Factor-alpha | 2006 |
CF-Emerging therapies: Modulation inflammation.
Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Bronchitis; Cystic Fibrosis; Deoxyribonuclease I; Free Radical Scavengers; Glucocorticoids; Humans; Inflammation; Pancreatic Elastase; Recombinant Proteins; Treatment Outcome | 2006 |
[New pharmacological options in the therapy of COPD].
Topics: Acetylcysteine; Administration, Inhalation; Adrenal Cortex Hormones; Anti-Bacterial Agents; Biomarkers; C-Reactive Protein; Forced Expiratory Volume; Humans; Inflammation; Macrolides; Pulmonary Disease, Chronic Obstructive; Reference Values | 2007 |
Antilipid mediator and antioxidant therapy in adult respiratory distress syndrome.
Topics: Acetylcysteine; Adrenal Cortex Hormones; Antioxidants; Clinical Trials as Topic; Disease Models, Animal; Epoprostenol; Humans; Inflammation; Intensive Care Units; Leukotrienes; Lipid Peroxidation; Middle Aged; Platelet Activating Factor; Respiratory Distress Syndrome; Thromboxanes; Treatment Failure | 1993 |
Significance of glutathione in lung disease and implications for therapy.
Topics: Acetylcysteine; Animals; Cysteine; Disease Models, Animal; Glutathione; Humans; Inflammation; Lung Diseases; NF-kappa B | 1994 |
N-acetylcysteine: potential for AIDS therapy.
Topics: Acetylcysteine; Acquired Immunodeficiency Syndrome; Cytokines; Drug Therapy, Combination; Glutathione; HIV Infections; Humans; Inflammation; Lymphocytes; Reactive Oxygen Species | 1993 |
Deciphering the oxyradical inflammation Rosetta stone: O2*-NO*, OONO-, polymorphonuclear neutrophils, poly(ADP-ribose) synthetase, systemic inflammatory response syndrome, and multiple organ dysfunction syndrome.
Topics: Acetylcysteine; Free Radical Scavengers; Humans; Inflammation; Multiple Organ Failure; Neutrophils; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Systemic Inflammatory Response Syndrome | 1999 |
Proteasome inhibitors.
Topics: Acetylcysteine; Animals; Coumarins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Drug Design; Humans; Hydrolysis; Inflammation; Isocoumarins; Macromolecular Substances; Molecular Weight; Multienzyme Complexes; Neoplasms; Peptides; Proteasome Endopeptidase Complex; Substrate Specificity | 2002 |
25 trial(s) available for acetylcysteine and Innate Inflammatory Response
| Article | Year |
|---|---|
Amiodarone with or without N-Acetylcysteine for the Prevention of Atrial Fibrillation after Thoracic Surgery: A Double-blind, Randomized Trial.
Topics: Acetylcysteine; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Coronary Artery Bypass; Double-Blind Method; Humans; Inflammation; Postoperative Complications; Thoracic Surgery | 2022 |
Supplementing Glycine and N-Acetylcysteine (GlyNAC) in Older Adults Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Physical Function, and Aging Hallmarks: A Randomized Clinical Trial.
Topics: Acetylcysteine; Aged; Aging; Animals; Dietary Supplements; Glutathione; Glycine; Health Promotion; Humans; Inflammation; Insulin Resistance; Mice; Mitochondria; Oxidative Stress | 2023 |
Evaluation of the efficacy and safety of oral N-acetylcysteine in patients with COVID-19 receiving the routine antiviral and hydroxychloroquine protocol: A randomized controlled clinical trial.
Topics: Acetylcysteine; Antiviral Agents; Atazanavir Sulfate; C-Reactive Protein; COVID-19; COVID-19 Drug Treatment; Humans; Hydroxychloroquine; Inflammation; Randomized Controlled Trials as Topic; Ritonavir; SARS-CoV-2 | 2023 |
Interleukin-6 and total antioxidant capacity levels following
Topics: Acetylcysteine; Antioxidants; Bipolar Disorder; Case-Control Studies; Depressive Disorder; Dietary Supplements; Double-Blind Method; Drug Therapy, Combination; Energy Metabolism; Female; Free Radical Scavengers; Humans; Inflammation; Interleukin-6; Male; Mitochondria; Oxidative Stress; Placebos; Treatment Outcome | 2020 |
N-Acetylcysteine Improves Inflammatory Response in COPD Patients by Regulating Th17/Treg Balance through Hypoxia Inducible Factor-1
Topics: Acetylcysteine; Administration, Oral; Aged; Down-Regulation; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Interleukin-10; Interleukin-17; Lymphocyte Count; Male; Pulmonary Disease, Chronic Obstructive; T-Lymphocytes, Regulatory; Th17 Cells; Up-Regulation | 2021 |
The effect of intravenous N-acetylcysteine on prevention of atrial fibrillation after coronary artery bypass graft surgery: a double-blind, randomised, placebo-controlled trial.
Topics: Acetylcysteine; Administration, Intravenous; Adult; Aged; Atrial Fibrillation; Coronary Artery Bypass; Double-Blind Method; Electrocardiography; Female; Humans; Inflammation; Male; Middle Aged; Monitoring, Physiologic; Postoperative Complications; Receptors, Immunologic; Treatment Outcome | 2018 |
N-acetylcysteine as add-on to antidepressant medication in therapy refractory major depressive disorder patients with increased inflammatory activity: study protocol of a double-blind randomized placebo-controlled trial.
Topics: Acetylcysteine; Adult; Antidepressive Agents; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Diffusion Tensor Imaging; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Free Radical Scavengers; Humans; Inflammation; Inflammation Mediators; Male; Oxidative Stress; Psychotherapy; Treatment Outcome | 2018 |
A Pilot Study to Evaluate the Effects of Oral N-Acetyl Cysteine on Inflammatory and Oxidative Stress Biomarkers in Rheumatoid Arthritis.
Topics: Acetylcysteine; Administration, Oral; Adult; Aged; Anti-Inflammatory Agents; Antioxidants; Antirheumatic Agents; Arthritis, Rheumatoid; Biomarkers; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Inflammation; Male; Middle Aged; Oxidative Stress; Pilot Projects | 2019 |
N-acetylcysteine improves oxidative stress and inflammatory response in patients with community acquired pneumonia: A randomized controlled trial.
Topics: Acetylcysteine; Adult; Antioxidants; Community-Acquired Infections; Female; Humans; Inflammation; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Pneumonia; Superoxide Dismutase; Treatment Outcome; Tumor Necrosis Factor-alpha | 2018 |
Thiol-based antioxidant supplementation alters human skeletal muscle signaling and attenuates its inflammatory response and recovery after intense eccentric exercise.
Topics: Acetylcysteine; Adaptation, Physiological; Adult; Antioxidants; Biomarkers; C-Reactive Protein; Creatine Kinase; Cross-Over Studies; Cytokines; Diet; Dietary Supplements; Double-Blind Method; Exercise; Glutathione; Humans; Immunohistochemistry; Inflammation; Male; Muscle Contraction; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Quadriceps Muscle; Ribosomal Protein S6; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sulfhydryl Compounds; Tumor Necrosis Factor-alpha; Young Adult | 2013 |
Oxidative status, inflammation, and postoperative atrial fibrillation with metoprolol vs carvedilol or carvedilol plus N-acetyl cysteine treatment.
Topics: Acetylcysteine; Aged; Antihypertensive Agents; Atrial Fibrillation; Carbazoles; Cardiac Surgical Procedures; Carvedilol; Double-Blind Method; Drug Therapy, Combination; Female; Free Radical Scavengers; Humans; Inflammation; Leukocyte Count; Male; Metoprolol; Middle Aged; Oxidative Stress; Postoperative Period; Propanolamines; Prospective Studies; Treatment Outcome | 2014 |
Effect of N-acetylcysteine on cycling performance after intensified training.
Topics: Acetylcysteine; Antioxidants; Bicycling; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Humans; Inflammation; Oxidation-Reduction; Oxidative Stress; Physical Education and Training; Physical Endurance | 2014 |
Antenatal pharmacokinetics and placental transfer of N-acetylcysteine in chorioamnionitis for fetal neuroprotection.
Topics: Acetylcysteine; Chorioamnionitis; Double-Blind Method; Female; Fetal Blood; Free Radical Scavengers; Humans; Inflammation; Infusions, Intravenous; Male; Maternal-Fetal Exchange; Mothers; Neuroprotective Agents; Pilot Projects; Placenta; Pregnancy; Prospective Studies; Time Factors | 2014 |
Long-term treatment with oral N-acetylcysteine: affects lung function but not sputum inflammation in cystic fibrosis subjects. A phase II randomized placebo-controlled trial.
Topics: Acetylcysteine; Administration, Oral; Adolescent; Adult; Antioxidants; Child; Cystic Fibrosis; Double-Blind Method; Drug Monitoring; Female; Humans; Inflammation; Leukocyte Elastase; Lung; Male; Oxidative Stress; Respiratory Function Tests; Sputum; Time; Treatment Outcome | 2015 |
The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection -- a pilot study.
Topics: Acetylcysteine; Administration, Oral; Adult; Antioxidants; Ascorbic Acid; Chronic Disease; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Monitoring; Female; Forced Expiratory Volume; Humans; Inflammation; Lung; Male; Middle Aged; Oxidative Stress; Pseudomonas Infections; Reactive Oxygen Species; Treatment Outcome | 2015 |
Effects of oral N-acetylcysteine on walking capacity, leg reactive hyperemia, and inflammatory and angiogenic mediators in patients with intermittent claudication.
Topics: Acetylcysteine; Administration, Oral; Aged; Antioxidants; Chemokine CCL2; Endothelins; Humans; Hyperemia; Inflammation; Intermittent Claudication; Leg; Male; MicroRNAs; Middle Aged; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Vascular Cell Adhesion Molecule-1; Vascular Endothelial Growth Factor A; Walking | 2015 |
Effect of N-acetylcysteine supplementation on oxidative stress status and alveolar inflammation in people exposed to asbestos: a double-blind, randomized clinical trial.
Topics: Acetylcysteine; Aged; Asbestos; Dietary Supplements; Double-Blind Method; Female; Free Radical Scavengers; Humans; Inflammation; Male; Middle Aged; Occupational Exposure; Oxidative Stress; Pneumonia; Treatment Outcome | 2015 |
Effect of N-acetylcysteine on inflammation biomarkers in pediatric acute pyelonephritis: a randomized controlled trial.
Topics: Acetylcysteine; Acute Disease; Biomarkers; C-Reactive Protein; Calcitonin; Calcitonin Gene-Related Peptide; Child; Child, Preschool; Creatinine; Double-Blind Method; Female; Free Radical Scavengers; Humans; Inflammation; Leukocyte Count; Male; Protein Precursors; Pyelonephritis | 2015 |
The effect of an oral anti-oxidant, N-Acetyl-cysteine, on inflammatory and oxidative markers in pulmonary sarcoidosis.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Administration, Oral; Adult; Aged; Antioxidants; Bronchoalveolar Lavage Fluid; Deoxyguanosine; DNA; Double-Blind Method; Female; Glutathione; Humans; Inflammation; Lipopolysaccharides; Male; Middle Aged; Oxidation-Reduction; Oxidative Stress; Sarcoidosis, Pulmonary; Tumor Necrosis Factor-alpha | 2016 |
N-acetylcysteine supplementation and oxidative damage and inflammatory response after eccentric exercise.
Topics: Acetylcysteine; Creatine Kinase; Dietary Supplements; Double-Blind Method; Elbow Joint; Exercise; Humans; Inflammation; Interleukin-10; Lipid Peroxidation; Lipid Peroxides; Male; Malondialdehyde; Muscle, Skeletal; Myoglobin; Oxidation-Reduction; Oxidative Stress; Tumor Necrosis Factor-alpha; Young Adult | 2008 |
Randomized clinical trial on acute effects of i.v. iron sucrose during haemodialysis.
Topics: Acetylcysteine; Aged; Antioxidants; Biomarkers; CD11b Antigen; CD18 Antigens; Cross-Over Studies; Endothelium, Vascular; Female; Ferric Compounds; Ferric Oxide, Saccharated; Glucaric Acid; Hematinics; Humans; Inflammation; Inflammation Mediators; Infusions, Intravenous; Intercellular Adhesion Molecule-1; Interleukin-8; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Prospective Studies; Renal Dialysis; Time Factors; Treatment Outcome; von Willebrand Factor | 2010 |
Systemic illness moderates the impact of N-acetyl cysteine in bipolar disorder.
Topics: Acetylcysteine; Adult; Bipolar Disorder; Cardiovascular Diseases; Double-Blind Method; Endocrine System Diseases; Female; Free Radical Scavengers; Humans; Inflammation; Male; Middle Aged; Oxidative Stress | 2012 |
Effect of oral N-acetylcysteine treatment on immune system in continuous ambulatory peritoneal dialysis patients.
Topics: Acetylcysteine; Adult; Antioxidants; Biomarkers; C-Reactive Protein; Calcitonin; Calcitonin Gene-Related Peptide; Complement C3; Female; Humans; Inflammation; Interleukin-1; Interleukin-6; Kidney Failure, Chronic; Male; Middle Aged; Oxidative Stress; Peritoneal Dialysis, Continuous Ambulatory; Protein Precursors; Tumor Necrosis Factor-alpha | 2012 |
[Effect of prophylactic N-acetylcysteine on postoperative organ dysfunction and inflammatory markers after major abdominal surgery for cancer. Prospective, randomized, double-blind, placebo-controlled clinical trial].
Topics: Abdominal Neoplasms; Acetylcysteine; Aged; Albuminuria; Biomarkers; C-Reactive Protein; Calcitonin; Calcitonin Gene-Related Peptide; Critical Care; Double-Blind Method; Female; Humans; Inflammation; Infusions, Intravenous; Length of Stay; Male; Middle Aged; Multiple Organ Failure; Prospective Studies; Protein Precursors; Respiration, Artificial; Treatment Outcome | 2002 |
N-acetylcysteine for preventing pump-induced oxidoinflammatory response during cardiopulmonary bypass.
Topics: Acetylcysteine; Acute-Phase Proteins; Antioxidants; C-Reactive Protein; Cardiopulmonary Bypass; Coronary Artery Bypass; Humans; Inflammation; Inflammation Mediators; Interleukin-6; Lipid Peroxidation; Malondialdehyde; Neutrophil Activation; Orosomucoid; Oxidative Stress; Peroxidase | 2004 |
268 other study(ies) available for acetylcysteine and Innate Inflammatory Response
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Inflammation; Kinetics; Microspheres; Peptide Hydrolases; Peptides; Reproducibility of Results; Temperature | 2010 |
Effect of natural and semi-synthetic cadinanes from Heterotheca inuloides on NF-κB, Nrf2 and STAT3 signaling pathways and evaluation of their in vitro cytotoxicity in human cancer cell lines.
Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Asteraceae; Cell Line, Tumor; Cell Proliferation; Humans; Inflammation; Molecular Docking Simulation; Neoplasms; NF-E2-Related Factor 2; NF-kappa B; Polycyclic Sesquiterpenes; Sesquiterpenes; Signal Transduction; STAT3 Transcription Factor | 2017 |
Design, synthesis and evaluation of diosgenin carbamate derivatives as multitarget anti-Alzheimer's disease agents.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Carbamates; Cell Line, Tumor; Cell Survival; Diosgenin; Dose-Response Relationship, Drug; Drug Design; Galactose; Humans; Inflammation; Male; Mice; Mice, Inbred ICR; Molecular Structure; Neuroprotective Agents; Oxidative Stress; Protein Aggregates; Structure-Activity Relationship | 2020 |
Design and synthesis of novel diosgenin-triazole hybrids targeting inflammation as potential neuroprotective agents.
Topics: Alzheimer Disease; Animals; Cell Line; Diosgenin; Dose-Response Relationship, Drug; Drug Design; Inflammation; Lipopolysaccharides; Molecular Conformation; Neuroprotective Agents; Nitric Oxide; Rats; Structure-Activity Relationship; Triazoles | 2021 |
Necrostatins regulate apoptosis, necroptosis, and inflammation in cisplatin-induced nephrotoxicity in LLC-PK1 cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cisplatin; Dose-Response Relationship, Drug; Epithelial Cells; Imidazoles; Indoles; Inflammation; Kidney Tubules; LLC-PK1 Cells; Molecular Structure; Necroptosis; Small Molecule Libraries; Structure-Activity Relationship; Swine | 2021 |
N-acetylcysteine supplementation did not reverse mitochondrial oxidative stress, apoptosis, and inflammation in the salivary glands of hyperglycemic rats.
Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Antioxidants; Apoptosis; Citrate (si)-Synthase; Diet, High-Fat; Dietary Supplements; Glutathione; Hydrogen Peroxide; Hyperglycemia; Inflammation; Male; Mitochondria; Oxidative Stress; Rats; Rats, Wistar; Salivary Glands | 2021 |
Effect of N-acetyl-L-cysteine on inflammation after intraperitoneal mesh placement in a potentially contaminated environment: An experimental study in the rat.
Topics: Acetylcysteine; Animals; Ciprofloxacin; Inflammation; Interleukin-6; Male; Rats; Rats, Wistar; Surgical Mesh; Tissue Adhesions | 2022 |
Maternal N-Acetyl-Cysteine Prevents Neonatal Hypoxia-Induced Brain Injury in a Rat Model.
Topics: Acetylcysteine; Animals; Animals, Newborn; Antioxidants; Asphyxia Neonatorum; Brain; Gene Expression Regulation; Hypoxia, Brain; In Situ Nick-End Labeling; Inflammation; Interleukin-6; Nitric Oxide Synthase Type I; Oxidative Stress; Rats; Rats, Sprague-Dawley; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2021 |
N-Acetylcysteine alleviates spinal cord injury in rats after early decompression surgery by regulating inflammation and apoptosis.
Topics: Acetylcysteine; Animals; Apoptosis; Decompression; Inflammation; Rats; Recovery of Function; Spinal Cord; Spinal Cord Injuries | 2022 |
ROS-NLRP3 signaling pathway induces sterile inflammation after thulium laser resection of the prostate.
Topics: Acetylcysteine; Animals; Caspase 1; Dogs; Humans; Inflammasomes; Inflammation; Interleukin-18; Interleukin-1beta; Lasers; Male; NLR Family, Pyrin Domain-Containing 3 Protein; Prostate; Reactive Oxygen Species; Signal Transduction; Thulium | 2022 |
Lung targeted liposomes for treating ARDS.
Topics: Acetylcysteine; Animals; COVID-19; Humans; Inflammation; Lipopolysaccharides; Liposomes; Lung; Lung Diseases; Mice; Mice, Inbred C57BL; Nanoparticles; Respiratory Distress Syndrome; Tumor Necrosis Factor-alpha | 2022 |
Acrylamide exposure increases cardiovascular risk of general adult population probably by inducing oxidative stress, inflammation, and TGF-β1: A prospective cohort study.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Acrylamide; Adult; Biomarkers; Cardiovascular Diseases; Cross-Sectional Studies; Heart Disease Risk Factors; Humans; Inflammation; Oxidative Stress; Prospective Studies; Risk Factors; Transforming Growth Factor beta1 | 2022 |
Cytokine profile and cholesterol levels in patients with Niemann-Pick type C disease presenting neurological symptoms: in vivo effect of miglustat and in vitro effect of N-acetylcysteine and coenzyme Q10.
Topics: 1-Deoxynojirimycin; Acetylcysteine; Antioxidants; Cholesterol; Cytokines; Enzyme Inhibitors; Humans; Inflammation; Niemann-Pick Disease, Type C; Ubiquinone | 2022 |
Nrf2 Activation Mediates Antiallodynic Effect of Electroacupuncture on a Rat Model of Complex Regional Pain Syndrome Type-I through Reducing Local Oxidative Stress and Inflammation.
Topics: Acetylcysteine; Animals; Antioxidants; Chronic Pain; Complex Regional Pain Syndromes; Electroacupuncture; Inflammation; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2022 |
Epigallocatechin-3-gallate attenuates cyclophosphamide-induced damage in mouse ovarian tissue via suppressing inflammation, apoptosis, and expression of phosphorylated Akt, FOXO3a and rpS6.
Topics: Acetylcysteine; Animals; Apoptosis; Body Weight; Caspase 3; Catechin; Cyclophosphamide; Female; Inflammation; Mice; Proto-Oncogene Proteins c-akt; Saline Solution; Tumor Necrosis Factor-alpha | 2022 |
Pyrogallol enhances therapeutic effect of human umbilical cord mesenchymal stem cells against LPS-mediated inflammation and lung injury via activation of Nrf2/HO-1 signaling.
Topics: Acetylcysteine; Acute Lung Injury; Animals; Heme Oxygenase-1; Humans; Inflammation; Inflammation Mediators; Kelch-Like ECH-Associated Protein 1; Lipopolysaccharides; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; NF-E2-Related Factor 2; NF-kappa B; Pyrogallol; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Toll-Like Receptor 4; Umbilical Cord | 2022 |
N-acetylcysteine attenuates atherosclerosis progression in aging LDL receptor deficient mice with preserved M2 macrophages and increased CD146.
Topics: Acetylcysteine; Aging; Animals; Atherosclerosis; CD146 Antigen; Diet, High-Fat; Hyperlipidemias; Inflammation; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Reactive Oxygen Species; Receptors, LDL | 2022 |
[Features of topical therapy of inflammatory pathology of nasal cavity].
Topics: Acetylcysteine; Expectorants; Humans; Hyaluronic Acid; Inflammation; Nasal Cavity | 2022 |
Effects of N-acetyl-l-cysteine on chronic heat stress-induced oxidative stress and inflammation in the ovaries of growing pullets.
Topics: Acetylcysteine; Animals; Antioxidants; Chickens; Cytokines; Female; Heat-Shock Response; Inflammation; Ovary; Oxidative Stress | 2023 |
Oxidative stress and viral Infections: rationale, experiences, and perspectives on N-acetylcysteine.
Topics: Acetylcysteine; Antioxidants; Humans; Inflammation; Oxidative Stress; Virus Diseases | 2022 |
N-acetyl-L-cysteine ameliorates gestational diabetes mellitus by inhibiting oxidative stress.
Topics: Acetylcysteine; Animals; Antioxidants; Diabetes, Gestational; Female; Humans; Inflammation; Mice; Oxidative Stress; Pregnancy | 2023 |
Effects of N-acetylcysteine on the inflammatory response and bacterial translocation in a model of intestinal obstruction and ischemia in rats.
Topics: Acetylcysteine; Animals; Bacterial Translocation; Inflammation; Interleukin-10; Interleukin-6; Intestinal Obstruction; Ischemia; Rats; Rats, Wistar; Resuscitation; Saline Solution, Hypertonic; Shock, Hemorrhagic; Tumor Necrosis Factor-alpha | 2023 |
N-Acetylcysteine Suppresses Microglial Inflammation and Induces Mortality Dose-Dependently via Tumor Necrosis Factor-α Signaling.
Topics: Acetylcysteine; Animals; Humans; Inflammation; Lipopolysaccharides; Mice; Microglia; Reactive Oxygen Species; Tumor Necrosis Factor-alpha | 2023 |
Acetylated Oligopeptide and N-acetyl cysteine Protected Against Oxidative Stress, Inflammation, Testicular-Blood Barrier Damage, and Testicular Cell Death in Iron-Overload Rat Model.
Topics: Acetylcysteine; Animals; Antioxidants; Beclin-1; Cell Death; Claudin-1; Dextrans; Glutathione; Inflammation; Iron; Iron Overload; Male; NF-kappa B; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Rats; Testis; Testosterone | 2023 |
N-Acetylcysteine May Regulate Altered Meteorin-Like Levels in Testicular Tissue due to Aluminum Exposure.
Topics: Acetylcysteine; Aluminum; Animals; Antioxidants; Inflammation; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Testis | 2023 |
A novel thiol-saccharide mucolytic for the treatment of muco-obstructive lung diseases.
Topics: Acetylcysteine; Adult; Animals; Carbohydrates; Cystic Fibrosis; Expectorants; Humans; Inflammation; Lung; Lung Diseases, Obstructive; Mice; Sputum; Sulfhydryl Compounds | 2023 |
Elevated LDL Cholesterol Increases Microvascular Endothelial VWF and Thromboinflammation After Myocardial Infarction.
Topics: Acetylcysteine; ADAMTS13 Protein; Animals; Cholesterol, LDL; Inflammation; Ischemia; Mice; Myocardial Infarction; Thromboinflammation; von Willebrand Factor | 2023 |
N-Acetyl cysteine amide and cerium oxide nanoparticles as a drug delivery for ischemic stroke treatment: Inflammation and oxidative stress crosstalk.
Topics: Acetylcysteine; Amides; Animals; Anti-Bacterial Agents; Antioxidants; Cerium; Chitinase-3-Like Protein 1; Drug Delivery Systems; Humans; Inflammation; Ischemic Stroke; Nanoparticles; Olive Oil; Oxidative Stress; Rats; Urea | 2023 |
N-acetyl cysteine inhibits IL-1α release from murine keratinocytes induced by 2-hydroxyethyl methacrylate.
Topics: Acetylcysteine; Animals; Calpain; Inflammation; Keratinocytes; Methacrylates; Mice; Reactive Oxygen Species | 2023 |
N-acetyl cysteine mitigates lung damage and inflammation after chlorine exposure in vivo and ex vivo.
Topics: Acetylcysteine; Animals; Antioxidants; Chlorine; Inflammation; Inflammation Mediators; Lung; Lung Injury; Mice; Swine | 2023 |
N-acetylcysteine ameliorates chemotherapy-induced impaired anxiety and depression-like behaviors by regulating inflammation, oxidative and cholinergic status, and BDNF release.
Topics: Acetylcholinesterase; Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Anxiety; Brain-Derived Neurotrophic Factor; Cholinergic Agents; Depression; Humans; Inflammation; Male; Methotrexate; Oxidative Stress; Rats; Rats, Wistar | 2024 |
Topics: Acetylcysteine; Anti-Inflammatory Agents; Biofilms; Catheters; Humans; Inflammation; Proteus Infections; Proteus mirabilis; Urease; Urinary Catheterization; Urinary Tract Infections | 2023 |
Redox regulation of hepatic NLRP3 inflammasome activation and immune dysregulation in trichloroethene-mediated autoimmunity.
Topics: Acetylcysteine; Anesthetics, Inhalation; Animals; Autoimmune Diseases; Female; Free Radical Scavengers; Inflammasomes; Inflammation; Liver; Mice; Mice, Inbred Strains; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Trichloroethylene | 2019 |
N-Acetylcysteine Resolves Placental Inflammatory-Vasculopathic Changes in Mice Consuming a High-Fat Diet.
Topics: Acetylcysteine; Animals; Diet, High-Fat; Disease Models, Animal; Female; Inflammation; Male; Maternal Nutritional Physiological Phenomena; Mice; Mice, Transgenic; Placenta; Pregnancy; Pregnancy Complications; Vascular Diseases | 2019 |
Interplay between oxidative stress and autophagy function and its role in inflammatory cytokine expression induced by palmitate in skeletal muscle cells.
Topics: Acetylcysteine; Adenine; Animals; Autophagy; Cell Line; Chloroquine; Cytokines; Free Radical Scavengers; Inflammation; Interleukin-6; Mice; Microtubule-Associated Proteins; Muscle, Skeletal; Oxidative Stress; Palmitates; Reactive Oxygen Species; Sequestosome-1 Protein; Sirolimus; Tumor Necrosis Factor-alpha | 2020 |
Temporal Dynamics of Reactive Oxygen and Nitrogen Species and NF-κB Activation During Acute and Chronic T Cell-Driven Inflammation.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Female; Free Radical Scavengers; Inflammation; Mice; Mice, Inbred C57BL; Mice, Transgenic; NF-kappa B; Optical Imaging; Picryl Chloride; Reactive Nitrogen Species; Reactive Oxygen Species; Signal Transduction; T-Lymphocytes | 2020 |
N‑acetyl cysteine protects HUVECs against lipopolysaccharide‑mediated inflammatory reaction by blocking the NF‑κB signaling pathway.
Topics: Acetylcysteine; Biomarkers; Cell Survival; Cytokines; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Inflammation Mediators; Intercellular Adhesion Molecule-1; Lipopolysaccharides; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Signal Transduction | 2019 |
Gold nanoparticles potentiates N-acetylcysteine effects on neurochemicals alterations in rats after polymicrobial sepsis.
Topics: Acetylcysteine; Animals; Antioxidants; Cytokines; Disease Models, Animal; Gold; Hippocampus; Inflammation; Male; Metal Nanoparticles; Mitochondria; Oxidation-Reduction; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Sepsis | 2020 |
Systemic LPS-induced neuroinflammation increases the susceptibility for proteasome inhibition-induced degeneration of the nigrostriatal pathway.
Topics: Acetylcysteine; Animals; Behavior, Animal; Corpus Striatum; Cysteine Proteinase Inhibitors; Disease Models, Animal; Illness Behavior; Inflammation; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Microglia; Nerve Degeneration; Neural Pathways; Proteasome Inhibitors; Substantia Nigra | 2019 |
The effect of N-acetylcysteine on inflammation and oxidative stress in cisplatin-induced nephrotoxicity: a rat model
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Antineoplastic Agents; Blood Urea Nitrogen; Cisplatin; Creatinine; Inflammation; Male; Oxidative Stress; Rats; Rats, Wistar; Treatment Outcome | 2019 |
Treatment of acetaminophen-induced liver failure by blocking the death checkpoint protein TRAIL.
Topics: Acetaminophen; Acetylcysteine; Animals; Apoptosis; Cell Line; Chemical and Drug Induced Liver Injury; Cytokines; Hepatocytes; Humans; Inflammation; Leukocytes; Liver; Liver Failure; Male; Mice; Mice, Inbred C57BL; Receptors, TNF-Related Apoptosis-Inducing Ligand; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand | 2020 |
Anti-inflammatory effects of Aureusidin in LPS-stimulated RAW264.7 macrophages via suppressing NF-κB and activating ROS- and MAPKs-dependent Nrf2/HO-1 signaling pathways.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Benzofurans; Heme Oxygenase-1; Humans; Inflammation; Lipopolysaccharides; MAP Kinase Signaling System; Membrane Proteins; Mice; Molecular Docking Simulation; NF-E2-Related Factor 2; NF-kappa B; Phosphorylation; RAW 264.7 Cells; Reactive Oxygen Species | 2020 |
Redox status, inflammation, necroptosis and inflammasome as indispensable contributors to high fat diet (HFD)-induced neurodegeneration; Effect of N-acetylcysteine (NAC).
Topics: Acetylcysteine; Animals; Antioxidants; Diet, High-Fat; Inflammasomes; Inflammation; Male; Necroptosis; Neurodegenerative Diseases; Oxidation-Reduction; Oxidative Stress; Rats, Wistar | 2020 |
Combination of sivelestat and N-acetylcysteine alleviates the inflammatory response and exceeds standard treatment for acetaminophen-induced liver injury.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Free Radical Scavengers; Glycine; Inflammation; Male; Mice; Mice, Inbred C57BL; Serine Proteinase Inhibitors; Sulfonamides | 2020 |
N-Acetyl cysteine effectively alleviates Coxsackievirus B-Induced myocarditis through suppressing viral replication and inflammatory response.
Topics: Acetylcysteine; Animals; Animals, Newborn; Antiviral Agents; Caspase Inhibitors; Coxsackievirus Infections; Enterovirus B, Human; HeLa Cells; Humans; Inflammation; Mice, Inbred BALB C; Myocarditis; Proteasome Endopeptidase Complex; Specific Pathogen-Free Organisms; Virus Replication | 2020 |
N-acetyl-L-cysteine reduces Leishmania amazonensis-induced inflammation in BALB/c mice.
Topics: Acetylcysteine; Animals; Cytokines; Hyperalgesia; Inflammation; Leishmania mexicana; Leishmaniasis, Cutaneous; Male; Mastocytosis; Mice, Inbred BALB C; Oxidative Stress | 2020 |
Mitigation of Glucolipotoxicity-Induced Apoptosis, Mitochondrial Dysfunction, and Metabolic Stress by
Topics: Acetylcysteine; Animals; Apoptosis; Autophagy; Cell Line; DNA Damage; DNA Fragmentation; Fatty Acids; Glucose; Inflammation; Insulin-Secreting Cells; Membrane Potential, Mitochondrial; Mitochondria; Oxidation-Reduction; Oxidative Stress; Palmitic Acid; Poly(ADP-ribose) Polymerases; Rats; Reactive Oxygen Species; Signal Transduction | 2020 |
N-acetylcysteine decreases airway inflammation and responsiveness in asthma by modulating claudin 18 expression.
Topics: Acetylcysteine; Animals; Asthma; Bronchoalveolar Lavage Fluid; Claudins; Disease Models, Animal; Female; Humans; Inflammation; Lung; Mice; Mice, Inbred BALB C; Ovalbumin | 2020 |
N-acetylcysteine alleviates liver injury by suppressing macrophage-mediated inflammatory response post microwave ablation.
Topics: Ablation Techniques; Acetylcysteine; Animals; Anti-Inflammatory Agents; Apoptosis; Carcinoma, Hepatocellular; Humans; Inflammation; Liver; Liver Diseases; Liver Neoplasms; Macrophages; Male; Microwaves; Peroxidase; Rats, Sprague-Dawley | 2020 |
Antioxidant Effects of N-Acetylcysteine Prevent Programmed Metabolic Disease in Mice.
Topics: Acetylcysteine; Adipose Tissue, Brown; Adipose Tissue, White; Adiposity; Animals; Antioxidants; Body Temperature; Calorimetry, Indirect; Diet, High-Fat; Female; Glucose Tolerance Test; Inflammation; Injections, Intraperitoneal; Insulin Resistance; Male; Metabolic Diseases; Mice; Weight Gain | 2020 |
N-Acetylcysteine: A potential therapeutic agent for SARS-CoV-2.
Topics: Acetylcysteine; Betacoronavirus; Clinical Trials as Topic; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Free Radicals; Glutathione; Humans; Inflammation; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidation-Reduction; Oxidative Stress; Pandemics; Pneumonia, Viral; SARS-CoV-2; Severe Acute Respiratory Syndrome; T-Lymphocytes; Tumor Necrosis Factor-alpha; Viral Load | 2020 |
High glucose-induced ROS accumulation is a critical regulator of ERK1/2-Akt-tuberin-mTOR signalling in RGC-5 cells.
Topics: Acetylcysteine; Animals; DNA, Mitochondrial; Enzyme Inhibitors; Gene Expression Regulation; Glucose; Human Umbilical Vein Endothelial Cells; Humans; Hyperglycemia; Inflammation; Interferon Regulatory Factor-3; Membrane Potential, Mitochondrial; Mice; Mitochondria; Mitogen-Activated Protein Kinase 3; NADPH Oxidases; Neurodegenerative Diseases; Oxidative Stress; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Retinal Ganglion Cells; RNA, Small Interfering; Signal Transduction; TOR Serine-Threonine Kinases; Tuberous Sclerosis Complex 2 Protein | 2020 |
Cytotoxicity of Saikosaponin A targets HEKa cell through apoptosis induction by ROS accumulation and inflammation suppression via NF-κB pathway.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Line; Humans; Imiquimod; Immunosuppression Therapy; Inflammation; Keratinocytes; Mice; NF-kappa B; Oleanolic Acid; Reactive Oxygen Species; Saponins; Signal Transduction | 2020 |
Therapeutic blockade of inflammation in severe COVID-19 infection with intravenous N-acetylcysteine.
Topics: Acetylcysteine; Adult; Antioxidants; Antirheumatic Agents; Betacoronavirus; Biomarkers; C-Reactive Protein; Coronavirus Infections; COVID-19; Cytokine Release Syndrome; Drug Administration Schedule; Ferritins; Fibrin Fibrinogen Degradation Products; Glucosephosphate Dehydrogenase Deficiency; Humans; Hydroxychloroquine; Inflammation; Male; Pandemics; Pneumonia, Viral; SARS-CoV-2; Treatment Outcome | 2020 |
Antifibrotic effect of curcumin, N-acetyl cysteine and propolis extract against bisphenol A-induced hepatotoxicity in rats: Prophylaxis versus co-treatment.
Topics: Acetylcysteine; Animals; Apoptosis; Benzhydryl Compounds; Chemical and Drug Induced Liver Injury; Curcumin; Drug Therapy, Combination; Inflammation; Interleukins; Liver; Liver Cirrhosis; Male; Phenols; Propolis; Rats; Rats, Wistar | 2020 |
Effectiveness of the integration of quercetin, turmeric, and N-acetylcysteine in reducing inflammation and pain associated with endometriosis. In-vitro and in-vivo studies.
Topics: Acetylcysteine; Curcuma; Dysmenorrhea; Dyspareunia; Endometriosis; Humans; Inflammation; Quercetin | 2020 |
A striking result from antenatal exposure to N-acetylcysteine.
Topics: Acetylcysteine; Female; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Inflammation; Pregnancy | 2021 |
N-acetylcysteine modulates non-esterified fatty acid-induced pyroptosis and inflammation in granulosa cells.
Topics: Acetylcysteine; Animals; Cattle; Cell Survival; Fatty Acids, Nonesterified; Female; Granulosa Cells; Inflammation; Inflammation Mediators; Ketosis; Models, Biological; Oxidation-Reduction; Oxidative Stress; Pyroptosis; Up-Regulation | 2020 |
N-Acetyl Cysteine Modulates the Inflammatory and Oxidative Stress Responses of Rescued Growth-Arrested Dental Pulp Microtissues Exposed to TEGDMA in ECM.
Topics: Acetylcysteine; Cell Proliferation; Composite Resins; Dental Pulp; Drug Evaluation, Preclinical; Extracellular Matrix; Gene Expression Regulation, Developmental; Humans; Inflammation; Interleukin-8; NF-E2-Related Factor 2; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Polyethylene Glycols; Polymethacrylic Acids | 2020 |
Engineered cardiac tissues: a novel in vitro model to investigate the pathophysiology of mouse diabetic cardiomyopathy.
Topics: Acetylcysteine; Animals; Benzamides; Cells, Cultured; Diabetic Cardiomyopathies; Glycation End Products, Advanced; Inflammation; Mice; Myocardium; Myocytes, Cardiac; Oxidative Stress; Receptor for Advanced Glycation End Products; Tissue Engineering | 2021 |
Maternal N-acetyl-cysteine prevents neonatal brain injury associated with necrotizing enterocolitis in a rat model.
Topics: Acetylcysteine; Animals; Animals, Newborn; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Brain Injuries; Caspase 3; Disease Models, Animal; Enterocolitis, Necrotizing; Female; In Situ Nick-End Labeling; Inflammation; Interleukin-1beta; Interleukin-6; Nitric Oxide Synthase Type I; Oxidative Stress; Pregnancy; Rats; Rats, Sprague-Dawley; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2021 |
Postprandial triglyceride-rich lipoproteins-induced premature senescence of adipose-derived mesenchymal stem cells via the SIRT1/p53/Ac-p53/p21 axis through oxidative mechanism.
Topics: Acetylation; Acetylcysteine; Adipogenesis; Animals; beta-Galactosidase; Cell Proliferation; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Down-Regulation; Inflammation; Lipoproteins; Mesenchymal Stem Cells; Mice; Obesity; Oxidative Stress; Postprandial Period; Reactive Oxygen Species; Sirtuin 1; Subcutaneous Fat; Triglycerides; Tumor Suppressor Protein p53; Up-Regulation | 2020 |
Systemic inflammation and oxidative stress contribute to acute kidney injury after transcatheter aortic valve implantation.
Topics: Acetylcysteine; Acute Kidney Injury; Aortic Valve; Aortic Valve Stenosis; Biomarkers; C-Reactive Protein; Humans; Inflammation; Interleukin-6; Oxidative Stress; Peroxidase; Transcatheter Aortic Valve Replacement; Treatment Outcome; Tumor Necrosis Factor-alpha | 2022 |
Effects of N-acetyl cysteine on mitochondrial ROS, mitochondrial dynamics, and inflammation on lipopolysaccharide-treated human apical papilla cells.
Topics: Acetylcysteine; Humans; Inflammation; Lipopolysaccharides; Mitochondria; Mitochondrial Dynamics; Reactive Oxygen Species | 2021 |
Possible protective activity of n-acetyl cysteine against cisplatin‑induced hepatotoxicity in rats.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Chemical and Drug Induced Liver Injury; Cisplatin; Humans; Inflammation; Liver; Neoplasms; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar | 2021 |
Alterations of mitochondrial dynamics, inflammation and mineralization potential of lipopolysaccharide-induced human dental pulp cells after exposure to N-acetyl cysteine, Biodentine or ProRoot MTA.
Topics: Acetylcysteine; Aluminum Compounds; Calcium Compounds; Cells, Cultured; Dental Pulp; Drug Combinations; Escherichia coli; Humans; Inflammation; Lipopolysaccharides; Mitochondrial Dynamics; Osteogenesis; Oxides; Root Canal Filling Materials; Silicates | 2021 |
Trehalose and N-Acetyl Cysteine Alleviate Inflammatory Cytokine Production and Oxidative Stress in LPS-Stimulated Human Peripheral Blood Mononuclear Cells.
Topics: Acetylcysteine; Anti-Inflammatory Agents; Antioxidants; Cytokines; Glutathione Peroxidase; Humans; Inflammation; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Leukocytes, Mononuclear; Lipopolysaccharides; Malondialdehyde; NF-kappa B; Oxidative Stress; Trehalose; Tumor Necrosis Factor-alpha | 2022 |
Lycopene Inhibits Oxidative Stress-Mediated Inflammatory Responses in Ethanol/Palmitoleic Acid-Stimulated Pancreatic Acinar AR42J Cells.
Topics: Acetylcysteine; Acinar Cells; Adenosine Triphosphate; Animals; Cell Line; DNA; Enzyme Inhibitors; Enzyme Precursors; Ethanol; Fatty Acids, Monounsaturated; Inflammation; Interleukin-6; Lycopene; Membrane Potential, Mitochondrial; Mitochondria; NADPH Oxidases; NF-kappa B; Oxidative Stress; Pancreas, Exocrine; Protein Binding; Rats; Reactive Oxygen Species | 2021 |
Effects of N-Acetyl Cysteine on Genes Expression of c-myc, and Ask-1, Histopathological, Oxidative Stress, Inflammation, and Apoptosis in the Liver of Male Rats Exposed to Cadmium.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Cadmium; Inflammation; Liver; Male; Oxidative Stress; Rats | 2022 |
Glycine and N-acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity, muscle strength, and cognition: Re
Topics: Acetylcysteine; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Cognition; Dietary Supplements; DNA Damage; Endothelium; Female; Free Radical Scavengers; Geriatric Assessment; Glutathione; Glycine; Glycine Agents; Humans; Inflammation; Insulin Resistance; Male; Mitochondria; Muscle Strength; Oxidative Stress; Pilot Projects; Young Adult | 2021 |
Acrylamide exposure and pulmonary function reduction in general population: The mediating effect of systemic inflammation.
Topics: Acetylcysteine; Acrylamide; Adult; Biomarkers; Cohort Studies; Humans; Inflammation | 2021 |
S-Allylmercapto-N-acetylcysteine ameliorates elastase-induced chronic obstructive pulmonary disease in mice via regulating autophagy.
Topics: A549 Cells; Acetylcysteine; Allyl Compounds; Animals; Autophagy; Disease Models, Animal; Humans; Inflammation; Lung; Mice; Mice, Inbred BALB C; Microtubule-Associated Proteins; Pancreatic Elastase; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pulmonary Disease, Chronic Obstructive; Swine; TOR Serine-Threonine Kinases; Up-Regulation; Weight Loss | 2021 |
PCB118 Induces Inflammation of Islet Beta Cells via Activating ROS-NLRP3 Inflammasome Signaling.
Topics: Acetylcysteine; Animals; Caspase 1; Cell Survival; Cytokines; Diabetes Mellitus; Inflammasomes; Inflammation; Interleukin-1beta; Islets of Langerhans; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Reactive Oxygen Species; Signal Transduction | 2021 |
Empagliflozin and neohesperidin protect against methotrexate-induced renal toxicity via suppression of oxidative stress and inflammation in male rats.
Topics: Acetylcysteine; Animals; Benzhydryl Compounds; Glucosides; Hesperidin; Inflammation; Kidney; Kidney Diseases; Male; Methotrexate; Oxidative Stress; Protective Agents; Rats; Signal Transduction | 2021 |
Drp1-dependent mitochondrial fission mediates osteogenic dysfunction in inflammation through elevated production of reactive oxygen species.
Topics: 3T3 Cells; Acetylcysteine; Animals; Dynamins; Inflammation; Mice; Mitochondrial Dynamics; Osteogenesis; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Tumor Necrosis Factor-alpha | 2017 |
A novel damage mechanism: Contribution of the interaction between necroptosis and ROS to high glucose-induced injury and inflammation in H9c2 cardiac cells.
Topics: Acetylcysteine; Animals; Cell Line; Gene Expression Regulation; Glucose; Inflammation; Myocytes, Cardiac; Rats; Reactive Oxygen Species; Receptor-Interacting Protein Serine-Threonine Kinases; Tumor Necrosis Factor-alpha | 2017 |
IFN-β-induced reactive oxygen species and mitochondrial damage contribute to muscle impairment and inflammation maintenance in dermatomyositis.
Topics: Acetylcysteine; Adult; Aged; Animals; Cell Line; Cytokines; Dermatomyositis; Female; Free Radical Scavengers; Freund's Adjuvant; Humans; Inflammation; Interferon-beta; Male; Mice, Inbred BALB C; Middle Aged; Mitochondria; Muscle Weakness; Muscle, Skeletal; Nervous System Autoimmune Disease, Experimental; Reactive Oxygen Species; Transcriptome | 2017 |
Minocycline plus N-acteylcysteine induces remyelination, synergistically protects oligodendrocytes and modifies neuroinflammation in a rat model of mild traumatic brain injury.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Antioxidants; Brain Injuries, Traumatic; Disease Models, Animal; Drug Synergism; Inflammation; Male; Minocycline; Oligodendroglia; Rats; Rats, Sprague-Dawley; Remyelination | 2018 |
The roles of NF-κB and ROS in regulation of pro-inflammatory mediators of inflammation induction in LPS-stimulated zebrafish embryos.
Topics: Acetylcysteine; Animals; Embryo, Nonmammalian; Fish Diseases; Fish Proteins; Gene Expression Regulation; Inflammation; Inflammation Mediators; Lipopolysaccharides; NF-kappa B; Pyrrolidines; Reactive Oxygen Species; Thiocarbamates; Zebrafish | 2017 |
Promoter methylation status in genes related with inflammation, nitrosative stress and xenobiotic metabolism in low-level benzene exposure: Searching for biomarkers of oncogenesis.
Topics: Acetylcysteine; Adult; Benzene; Biomarkers; Carcinogenesis; Cytochrome P-450 CYP2E1; DNA Methylation; Epigenesis, Genetic; Female; Humans; Inflammation; Inhalation Exposure; Interleukin-6; Male; Middle Aged; Neoplasms; Nitrosative Stress; Promoter Regions, Genetic; Xenobiotics; Young Adult | 2017 |
Protective effects of phloridzin against methotrexate-induced liver toxicity in rats.
Topics: Acetylcysteine; Animals; Biomarkers; Caspase 3; Inflammation; Liver; Male; Methotrexate; Oxidative Stress; Phlorhizin; Protective Agents; Rats; Survival Analysis | 2017 |
Acute maternal oxidant exposure causes susceptibility of the fetal brain to inflammation and oxidative stress.
Topics: Acetylcysteine; Animals; Antimetabolites; Brain; Buthionine Sulfoximine; Cytokines; Enzyme-Linked Immunosorbent Assay; Ethanol; Female; Fetus; Free Radical Scavengers; Glutathione; Inflammation; Male; Mice; Oxidative Stress; Pregnancy; Prenatal Exposure Delayed Effects; RNA, Messenger | 2017 |
Poly-MVA attenuates 7,12- dimethylbenz[a]anthracene initiated and croton oil promoted skin papilloma formation on mice skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetylcysteine; Animals; Carcinogens; Croton Oil; Dietary Supplements; Female; Free Radical Scavengers; Inflammation; Lipid Peroxidation; Mice; Molybdenum; N-Formylmethionine; Palladium; Papilloma; Rhodium; Ruthenium; Skin Neoplasms; Thioctic Acid; Vitamin B Complex | 2017 |
N-acetylcysteine effects on a murine model of chronic critical limb ischemia.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Hindlimb; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Interleukin-6; Ischemia; Lactic Acid; Male; Muscle, Skeletal; Nitrates; Nitrites; Oxidative Stress; Oxygen; Oxygen Consumption; Peroxidase; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Vascular Endothelial Growth Factor A | 2018 |
Fine chalk dust induces inflammatory response via p38 and ERK MAPK pathway in rat lung.
Topics: Acetylcysteine; Air Pollutants; Animals; Calcium Carbonate; Dietary Supplements; Dust; Inflammation; Lung; Male; MAP Kinase Signaling System; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Wistar; Up-Regulation | 2018 |
Oxidative stress-induced inflammatory responses and effects of N-acetylcysteine in bovine mammary alveolar cells.
Topics: Acetylcysteine; Animals; Cattle; Cells, Cultured; Cyclooxygenase 2; Epithelial Cells; Female; Humans; Inflammation; Mammary Glands, Animal; MAP Kinase Signaling System; Mastitis, Bovine; NF-kappa B; Oxidative Stress; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Vitamin K 3 | 2017 |
N-acetylcysteine (NAC) ameliorates Epstein-Barr virus latent membrane protein 1 induced chronic inflammation.
Topics: Acetylcysteine; Animals; Chronic Disease; Herpesvirus 4, Human; Inflammation; Mice; Mice, Transgenic; Viral Matrix Proteins | 2017 |
Analysis of oxidative stress-related markers in critically ill polytrauma patients: An observational prospective single-center study.
Topics: Acetylcysteine; Adult; Antioxidants; APACHE; Ascorbic Acid; Biomarkers; Critical Care; Critical Illness; Female; Humans; Inflammation; Lipid Peroxidation; Lipids; Male; Middle Aged; Multiple Trauma; Oxidative Stress; Partial Thromboplastin Time; Prospective Studies; Sepsis; Treatment Outcome | 2018 |
MicroRNA‑146a/NAPDH oxidase4 decreases reactive oxygen species generation and inflammation in a diabetic nephropathy model.
Topics: Acetylcysteine; Animals; Antagomirs; Cell Line; Diabetic Nephropathies; Disease Models, Animal; Glucose; Humans; Inflammation; Intercellular Adhesion Molecule-1; Male; Mice; Mice, Inbred C57BL; MicroRNAs; NADPH Oxidase 4; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; Vascular Cell Adhesion Molecule-1 | 2018 |
Therapeutic N-Acetyl-Cysteine (Nac) Following Initiation of Maternal Inflammation Attenuates Long-Term Offspring Cerebral Injury, as Evident in Magnetic Resonance Imaging (MRI).
Topics: Acetylcysteine; Animals; Brain; Brain Injuries; Disease Models, Animal; Escherichia coli; Female; Inflammation; Lipopolysaccharides; Male; Neuroprotective Agents; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Random Allocation; Rats, Sprague-Dawley | 2019 |
Acrylamide-induced oxidative stress and inflammatory response are alleviated by N-acetylcysteine in PC12 cells: Involvement of the crosstalk between Nrf2 and NF-κB pathways regulated by MAPKs.
Topics: Acetylcysteine; Acrylamide; Animals; Cytokines; Free Radical Scavengers; Inflammation; Lipid Peroxidation; Mitogen-Activated Protein Kinases; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species; Receptor Cross-Talk; Signal Transduction | 2018 |
NF-κB/p53-activated inflammatory response involves in diquat-induced mitochondrial dysfunction and apoptosis.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Caspase 3; Cyclooxygenase 2 Inhibitors; Diquat; Herbicides; Inflammation; Meloxicam; Mitochondria; NF-kappa B; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species; Signal Transduction; Thiazines; Thiazoles; Tumor Suppressor Protein p53 | 2018 |
Improved Cardiovascular Function in Old Mice After N-Acetyl Cysteine and Glycine Supplemented Diet: Inflammation and Mitochondrial Factors.
Topics: Acetylcysteine; Aging; Animals; Antioxidants; Cardiovascular Physiological Phenomena; Cellular Senescence; Diet Therapy; Dietary Supplements; Glutathione; Glycine; Inflammation; Mice; Mitochondria; Oxidative Stress | 2018 |
Protective Effect of Quercetin in LPS-Induced Murine Acute Lung Injury Mediated by cAMP-Epac Pathway.
Topics: Acetylcysteine; Acute Lung Injury; Animals; Cell Line; Cyclic AMP; Erythromycin; Inflammation; Inflammation Mediators; Lipopolysaccharides; Lung; Mice; Protective Agents; Quercetin | 2018 |
Kaempferol protects against propacetamol-induced acute liver injury through CYP2E1 inactivation, UGT1A1 activation, and attenuation of oxidative stress, inflammation and apoptosis in mice.
Topics: Acetaminophen; Acetylcysteine; Acute Lung Injury; Animals; Apoptosis; Cytochrome P-450 CYP2E1; DNA Damage; Extracellular Signal-Regulated MAP Kinases; Glucuronosyltransferase; Inflammation; Kaempferols; Male; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; Oxidative Stress; Superoxide Dismutase | 2018 |
N-Acetylcysteine protects human bronchi by modulating the release of neurokinin A in an ex vivo model of COPD exacerbation.
Topics: Acetylcysteine; Biological Availability; Bronchi; Disease Progression; Female; Humans; Inflammation; Lipopolysaccharides; Male; Middle Aged; Models, Biological; Neurokinin A; Oxidative Stress; Protective Agents; Pulmonary Disease, Chronic Obstructive; Regression Analysis | 2018 |
Pathogenesis of Abnormal Hepatic Lipid Metabolism Induced by Chronic Intermittent Hypoxia in Rats and the Therapeutic Effect of N-Acetylcysteine.
Topics: Acetylcysteine; Animals; Body Weight; Cytokines; Hypoxia; Inflammation; Lipid Metabolism; Liver; Male; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Signal Transduction | 2018 |
Inflammation induces Epac-protein kinase C alpha and epsilon signaling in TRPV1-mediated hyperalgesia.
Topics: Acetylcysteine; Action Potentials; Animals; Biotinylation; Capsaicin; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Erythromycin; Freund's Adjuvant; Ganglia, Spinal; Hyperalgesia; Inflammation; Male; Neurons; Patch-Clamp Techniques; Protein Kinase C-alpha; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X4; Signal Transduction; TRPV Cation Channels | 2018 |
Pro-inflammatory effects of e-cigarette vapour condensate on human alveolar macrophages.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Cell Survival; Chemokine CCL2; Complex Mixtures; Electronic Nicotine Delivery Systems; Gases; Humans; Inflammation; Interleukin-6; Interleukin-8; Macrophages, Alveolar; Matrix Metalloproteinase 9; Necrosis; Nicotine; Phagocytosis; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Reactive Oxygen Species; THP-1 Cells; Tumor Necrosis Factor-alpha; Vaping | 2018 |
IL-17A-induced neutrophilic airway inflammation is mediated by oxidant-antioxidant imbalance and inflammatory cytokines in mice.
Topics: Acetylcysteine; Animals; Antioxidants; Chemokine CCL2; Chemokine CXCL2; Chemokines; Cytokines; Inflammation; Interleukin-17; Interleukin-6; Lung; Male; Mice; Mice, Inbred BALB C; Neutrophils; Oxidants; Oxidative Stress; Pneumonia | 2018 |
Oxidative Imbalance, Nitrative Stress, and Inflammation in C6 Glial Cells Exposed to Hexacosanoic Acid: Protective Effect of N-acetyl-L-cysteine, Trolox, and Rosuvastatin.
Topics: Acetylcysteine; Animals; Antioxidants; Catalase; Cell Survival; Chromans; Cytoplasmic Vesicles; DNA Damage; Fatty Acids; Inflammation; Interleukin-1beta; Isoprostanes; Neuroglia; Neuroprotective Agents; Nitrates; Nitrites; Nitrosative Stress; Oxidative Stress; Rats; Rosuvastatin Calcium | 2018 |
Prolonged PM2.5 exposure elevates risk of oxidative stress-driven nonalcoholic fatty liver disease by triggering increase of dyslipidemia.
Topics: Acetylcysteine; Air Pollutants; Animals; Dyslipidemias; Hepatocytes; Humans; Inflammation; Insulin Resistance; Lipid Metabolism; Liver; Metabolic Syndrome; Mice; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Particulate Matter; Pyrrolidines; Signal Transduction; Thiocarbamates | 2019 |
N-acetylcysteine attenuates neuroinflammation associated depressive behavior induced by chronic unpredictable mild stress in rat.
Topics: Acetylcysteine; Animals; Antidepressive Agents; Behavior, Animal; Cytokines; Depression; Depressive Disorder; Disease Models, Animal; Fluoxetine; Hippocampus; Inflammation; Male; Neuroimmunomodulation; Rats; Rats, Wistar; Serotonin; Stress, Physiological; Stress, Psychological | 2019 |
N-acetylcysteine and alpha-lipoic acid improve antioxidant defenses and decrease oxidative stress, inflammation and serum lipid levels in ovariectomized rats via estrogen-independent mechanisms.
Topics: Acetylcysteine; Animals; Antioxidants; Cytokines; Dietary Supplements; Estrogens; Female; Glutathione; Inflammation; Lipids; NF-E2-Related Factor 2; Ovariectomy; Oxidative Stress; Rats, Wistar; Thioctic Acid | 2019 |
Role of autophagy in LPS‑induced inflammation in INS‑1 cells.
Topics: Acetylcysteine; Adenine; Animals; Apoptosis; Autophagy; Caspase 1; Cell Line; Inflammasomes; Inflammation; Interleukin-1beta; Lipopolysaccharides; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Reactive Oxygen Species | 2019 |
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Apoptosis; Cisplatin; Complement C5a; Disease Models, Animal; Inflammation; Kidney; Male; Mice; Mice, Inbred C57BL; Neutrophils; Oxidative Stress; Receptor, Anaphylatoxin C5a | 2019 |
N-acetylcysteine prevents bladder tissue fibrosis in a lipopolysaccharide-induced cystitis rat model.
Topics: Acetylcysteine; Animals; CARD Signaling Adaptor Proteins; Chemokine CXCL10; Cystitis; Disease Models, Animal; Female; Fibrosis; Gene Expression Profiling; Inflammation; Lipopolysaccharides; Protamines; Rats; Rats, Sprague-Dawley; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta2; Transforming Growth Factor beta3; Urinary Bladder | 2019 |
N-acetyl cysteine, inulin and the two as a combined therapy ameliorate cognitive decline in testosterone-deprived rats.
Topics: Acetylcysteine; Animals; Apoptosis; Astrocytes; Blood-Brain Barrier; Brain; Castration; Cognition; Cognitive Dysfunction; Disease Models, Animal; Drug Therapy, Combination; Dysbiosis; Hippocampus; Inflammation; Inulin; Male; Malondialdehyde; Microglia; Motor Activity; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Testosterone | 2019 |
Prophylactic maternal N-acetylcysteine in rats prevents maternal inflammation-induced offspring cerebral injury shown on magnetic resonance imaging.
Topics: Acetylcysteine; Animals; Animals, Newborn; Brain; Brain Injuries; Female; Infectious Disease Transmission, Vertical; Inflammation; Lipopolysaccharides; Magnetic Resonance Imaging; Pregnancy; Pregnancy, Animal; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley | 2013 |
The relationship between N-acetylcysteine, hyperbaric oxygen, and inflammation in a rat model of acetaminophen-induced nephrotoxicity.
Topics: Acetaminophen; Acetylcysteine; Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Creatinine; Free Radical Scavengers; Hyperbaric Oxygenation; Inflammation; Interleukin-6; Male; Neopterin; Oxygen; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Urea | 2013 |
Antioxidants inhibit SAA formation and pro-inflammatory cytokine release in a human cell model of alkaptonuria.
Topics: Acetylcysteine; Alkaptonuria; Antioxidants; Ascorbic Acid; Cell Line; Chondrocytes; Cytokines; Humans; Inflammation; Lipid Peroxidation; Phytic Acid; Serum Amyloid A Protein; Taurine; Thioctic Acid | 2013 |
High-dose N-acetylcysteine decreases silica-induced lung fibrosis in the rat.
Topics: Acetylcysteine; Administration, Oral; Animals; Antioxidants; Bronchoalveolar Lavage Fluid; C-Reactive Protein; Hydroxyproline; Inflammation; Interleukin-8; Lung; Male; Malondialdehyde; Pulmonary Fibrosis; Rats; Rats, Wistar; Silicon Dioxide; Tumor Necrosis Factor-alpha | 2013 |
Roles of lipoxin A4 in preventing paracetamol-induced acute hepatic injury in a rabbit model.
Topics: Acetaminophen; Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Chemical and Drug Induced Liver Injury; Hepatocytes; Inflammation; Interleukin-10; Lipoxins; Liver; Male; Rabbits; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2013 |
Role of aldose reductase in the metabolism and detoxification of carnosine-acrolein conjugates.
Topics: Acetylcysteine; Acrolein; Aldehyde Reductase; Animals; Antioxidants; Carnosine; Humans; Inflammation; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Reperfusion Injury; Tissue Distribution | 2013 |
Minocycline plus N-acetylcysteine synergize to modulate inflammation and prevent cognitive and memory deficits in a rat model of mild traumatic brain injury.
Topics: Acetylcysteine; Animals; Avoidance Learning; Brain Injuries; Cognition Disorders; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Inflammation; Memory Disorders; Minocycline; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 2013 |
Advanced oxidation protein products induce inflammatory response in fibroblast-like synoviocytes through NADPH oxidase -dependent activation of NF-κB.
Topics: Acetylcysteine; Advanced Oxidation Protein Products; Animals; Enzyme-Linked Immunosorbent Assay; Female; Inflammation; NADPH Oxidases; NF-kappa B; Protein Binding; Rats; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Signal Transduction; Superoxide Dismutase; Synovial Membrane; Tumor Necrosis Factor-alpha | 2013 |
Humic acid in drinking well water induces inflammation through reactive oxygen species generation and activation of nuclear factor-κB/activator protein-1 signaling pathways: a possible role in atherosclerosis.
Topics: Acetylcysteine; Animals; Antioxidants; Atherosclerosis; Cell Line, Tumor; Cell Survival; Cyclooxygenase 2; Dinoprostone; Drinking Water; Female; Gene Expression Regulation; Heme Oxygenase-1; Humic Substances; Inflammation; Interleukin-1beta; Membrane Proteins; Mice; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Reactive Oxygen Species; Signal Transduction; Taiwan; Transcription Factor AP-1; Tumor Necrosis Factor-alpha | 2014 |
Angiopoietin-like protein 2 accelerates carcinogenesis by activating chronic inflammation and oxidative stress.
Topics: Acetylcysteine; Angiopoietins; Animals; Carcinoma, Squamous Cell; DNA Methylation; Gene Expression Regulation, Neoplastic; Inflammation; Male; Mice; Mice, Knockout; MutS Homolog 2 Protein; Neoplasms, Experimental; Oxidative Stress; Promoter Regions, Genetic; Skin Neoplasms | 2014 |
Ischaemia-reperfusion injury: a major protagonist in kidney transplantation.
Topics: Acetylcysteine; Animals; Antioxidants; Arginine; Cold Ischemia; Complement C5a; Delayed Graft Function; Dendritic Cells; Graft Survival; Humans; Immunity, Innate; Inflammation; Kidney; Kidney Transplantation; Male; Reperfusion Injury; Tissue Donors; Toll-Like Receptors; Warm Ischemia | 2014 |
Exogenous hydrogen sulfide protects against doxorubicin-induced inflammation and cytotoxicity by inhibiting p38MAPK/NFκB pathway in H9c2 cardiac cells.
Topics: Acetylcysteine; Animals; Antibiotics, Antineoplastic; Cell Line; Cell Survival; Doxorubicin; Inflammation; Interleukin-1beta; Interleukin-6; NF-kappa B; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proline; Rats; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction; Sulfites; Thiocarbamates; Tumor Necrosis Factor-alpha | 2013 |
Nicotine mediates hypochlorous acid-induced nuclear protein damage in mammalian cells.
Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Cell Line; Cell Proliferation; Chromans; Glutathione; Humans; Hypochlorous Acid; Inflammation; Kidney; Lung; Neutrophils; Nicotine; Oxidation-Reduction; Proliferating Cell Nuclear Antigen | 2014 |
Molecular and physiological events in respiratory muscles and blood of rats exposed to inspiratory threshold loading.
Topics: Acetylcysteine; Animals; Antibodies, Monoclonal; Antioxidants; Biomechanical Phenomena; Inflammation; Infliximab; Male; Muscle Contraction; Muscle, Skeletal; Oxidative Stress; Random Allocation; Rats; Rats, Wistar; Regeneration; Respiratory Muscles; Specific Pathogen-Free Organisms; Tumor Necrosis Factor-alpha | 2014 |
Effects of cytokine-suppressive anti-inflammatory drugs on inflammatory activation in ex vivo human and ovine fetal membranes.
Topics: Acetylcysteine; Amides; Animals; Anti-Inflammatory Agents; Cell-Penetrating Peptides; Cells, Cultured; Cytokines; Dinoprostone; Extraembryonic Membranes; Female; Humans; Imidazoles; Inflammation; Pregnancy; Pyrimidines; Sheep; Thiophenes | 2014 |
Inhibitory effect of N-acetyl cysteine and ascorbic acid on the development of myringosclerosis: an experimental study.
Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Disease Models, Animal; Female; Fibrin Foam; Fibroblasts; Free Radical Scavengers; Guinea Pigs; Hemostatics; Immunohistochemistry; Inflammation; Leukocytes; Microscopy; Mucous Membrane; Myringosclerosis; Nitric Oxide Synthase; Random Allocation; Transforming Growth Factor beta; Tympanic Membrane; Vascular Endothelial Growth Factor A | 2014 |
Antioxidant and anti-inflammatory effects of N-acetylcysteine against malathion-induced liver damages and immunotoxicity in rats.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Biomarkers; Blotting, Western; Cell Proliferation; Chemical and Drug Induced Liver Injury; Cytokines; Flow Cytometry; Free Radical Scavengers; Inflammation; Insecticides; Leukocytes; Lipid Peroxidation; Liver; Lymphocytes; Malathion; Male; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2014 |
Asbestos modulates thioredoxin-thioredoxin interacting protein interaction to regulate inflammasome activation.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Asbestos, Crocidolite; Blotting, Western; Caspase 1; Cell Line, Tumor; Dehydroascorbic Acid; Dinitrochlorobenzene; Enzyme Activation; Epithelium; Gene Knockdown Techniques; Humans; Inflammation; L-Lactate Dehydrogenase; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; RNA, Small Interfering; Thioredoxin Reductase 1; Thioredoxins | 2014 |
Alpha-lipoic acid exerts anti-inflammatory effects on lipopolysaccharide-stimulated rat mesangial cells via inhibition of nuclear factor kappa B (NF-κB) signaling pathway.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Antioxidants; Cell Line; Cell Survival; Cyclooxygenase 2; Dinoprostone; I-kappa B Kinase; I-kappa B Proteins; Inflammation; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Mesangial Cells; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Rats; Sepsis; Signal Transduction; Thioctic Acid; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2015 |
[Effect of N-acetylcysteine on intestinal injury induced by cardiopulmonary bypass in rats].
Topics: Acetylcysteine; Animals; Cardiopulmonary Bypass; Glutathione; Glutathione Peroxidase; Inflammation; Interleukin-6; Intestines; Malondialdehyde; Oxidative Stress; Rats; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2014 |
Anti-inflammatory and heme oxygenase-1 inducing activities of lanostane triterpenes isolated from mushroom Ganoderma lucidum in RAW264.7 cells.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Cell Line; Cell Survival; Chromones; Enzyme Inhibitors; Heme Oxygenase-1; Inflammation; Macrophages; Mice; Morpholines; Reishi; Reverse Transcriptase Polymerase Chain Reaction; RNA; Triterpenes | 2014 |
Effect of N-acetylcysteine plus deferoxamine on oxidative stress and inflammation in dystrophic muscle cells.
Topics: Acetylcysteine; Aldehydes; Animals; Cells, Cultured; Deferoxamine; Hydrogen Peroxide; Inflammation; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle, Skeletal; Muscular Dystrophy, Duchenne; NF-kappa B; Oxidative Stress; Tumor Necrosis Factor-alpha | 2015 |
Antioxidants inhibit the inflammatory and apoptotic processes in an intermittent hypoxia model of sleep apnea.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Caspases; Disease Models, Animal; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Liver; Male; Melatonin; Mice; Mice, Inbred BALB C; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Sleep Apnea Syndromes; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2015 |
Effective inhibition of cardiomyocyte apoptosis through the combination of trimetazidine and N-acetylcysteine in a rat model of myocardial ischemia and reperfusion injury.
Topics: Acetylcysteine; Animals; Apoptosis; Blood Pressure; Caspase 3; Cell Death; Coronary Vessels; Disease Models, Animal; Fatty Acids; Glucose; Glutathione; Inflammation; Male; Malondialdehyde; Myocardial Ischemia; Myocardium; Myocytes, Cardiac; Oxidative Stress; Oxygen; Rats; Rats, Wistar; Reperfusion Injury; S100 Calcium Binding Protein beta Subunit; Trimetazidine | 2014 |
Impaired autophagy induces chronic atrophic pancreatitis in mice via sex- and nutrition-dependent processes.
Topics: Acetylcysteine; Animals; Atrophy; Autophagy; Autophagy-Related Protein 5; Endoplasmic Reticulum Stress; Female; Free Radical Scavengers; Humans; Inflammation; Male; Mice; Mice, Knockout; Microtubule-Associated Proteins; NAD(P)H Dehydrogenase (Quinone); Palm Oil; Pancreas; Pancreatitis, Chronic; Plant Oils; Reactive Oxygen Species; Sex Factors; Tumor Suppressor Protein p53 | 2015 |
The role of NF-κB signaling pathway in polyhexamethylene guanidine phosphate induced inflammatory response in mouse macrophage RAW264.7 cells.
Topics: Acetylcysteine; Animals; Antioxidants; Cell Line; Cell Survival; Cytokines; Dose-Response Relationship, Drug; Female; Genes, Reporter; Guanidines; Inflammation; Macrophages; Mice; NF-kappa B; Pregnancy; Reactive Oxygen Species; Signal Transduction | 2015 |
Investigating the immunomodulatory nature of zinc oxide nanoparticles at sub-cytotoxic levels in vitro and after intranasal instillation in vivo.
Topics: Acetylcysteine; Administration, Intranasal; Animals; Cell Line; Dose-Response Relationship, Drug; Epithelial Cells; Female; Heme Oxygenase-1; Humans; Immunologic Factors; Inflammation; Interleukin-8; MAP Kinase Signaling System; Metal Nanoparticles; Mice, Inbred BALB C; NF-kappa B; Toxicity Tests; Zinc Oxide | 2015 |
Cytoglobin deficiency promotes liver cancer development from hepatosteatosis through activation of the oxidative stress pathway.
Topics: Acetylcysteine; Animals; Antioxidants; Cytoglobin; Diet; Globins; Hepatic Stellate Cells; Humans; Inflammation; Liver; Liver Cirrhosis; Liver Neoplasms; Macrophages; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Oxidation-Reduction; Oxidative Stress; Precancerous Conditions | 2015 |
Reactive oxygen species activated NLRP3 inflammasomes initiate inflammation in hyperosmolarity stressed human corneal epithelial cells and environment-induced dry eye patients.
Topics: Acetylcysteine; Adult; Blotting, Western; Carrier Proteins; Caspase 1; Cell Line; Dry Eye Syndromes; Enzyme-Linked Immunosorbent Assay; Epithelium, Corneal; Female; Gene Knockdown Techniques; Humans; Inflammasomes; Inflammation; Interleukin-1beta; Keratitis; Male; Middle Aged; NLR Family, Pyrin Domain-Containing 3 Protein; Osmotic Pressure; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Transfection; Young Adult | 2015 |
Organic extracts from African dust storms stimulate oxidative stress and induce inflammatory responses in human lung cells through Nrf2 but not NF-κB.
Topics: Acetylcysteine; Africa; Air Movements; Air Pollutants; Cell Line; Deferoxamine; Dust; Glutathione S-Transferase pi; Heme Oxygenase-1; Humans; Inflammation; Interleukin-6; Interleukin-8; Lung; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Puerto Rico; Reactive Oxygen Species; RNA, Messenger | 2015 |
Enhancement of the acrolein-induced production of reactive oxygen species and lung injury by GADD34.
Topics: Acetylcysteine; Acrolein; Animals; Apoptosis; Cells, Cultured; Endoplasmic Reticulum Stress; Epithelial Cells; Female; Inflammation; Lung; Lung Injury; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; Protein Phosphatase 1; Protein Serine-Threonine Kinases; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering | 2015 |
Involvement of smad2 and Erk/Akt cascade in TGF-β1-induced apoptosis in human gingival epithelial cells.
Topics: Acetylcysteine; Apoptosis; Benzamides; Caspase 3; Caspase 7; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dioxoles; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Gingiva; Humans; Inflammation; MAP Kinase Signaling System; Periodontitis; Phosphorylation; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Signal Transduction; Smad2 Protein; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2015 |
Gold nanoparticles and/or N-acetylcysteine mediate carrageenan-induced inflammation and oxidative stress in a concentration-dependent manner.
Topics: Acetylcysteine; Animals; Carrageenan; Dose-Response Relationship, Drug; Gold; Inflammation; Interleukin-10; Interleukin-1beta; Male; Metal Nanoparticles; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2015 |
The combination of N-acetyl cysteine, alpha-lipoic acid, and bromelain shows high anti-inflammatory properties in novel in vivo and in vitro models of endometriosis.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Apoptosis; Bromelains; Cells, Cultured; Disease Models, Animal; Endometriosis; Endothelial Cells; Female; Humans; Inflammation; Mice; Mice, SCID; Microscopy, Fluorescence; Thioctic Acid; Tumor Necrosis Factor-alpha; Uterus; Vascular Cell Adhesion Molecule-1 | 2015 |
Endogenous GLP-1 as a key self-defense molecule against lipotoxicity in pancreatic islets.
Topics: Acetylcysteine; Animals; Apoptosis; Cell Survival; Cells, Cultured; Diet, High-Fat; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Secreting Cells; Homeodomain Proteins; Inflammation; Insulin-Secreting Cells; Liraglutide; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Palmitates; Peptide Fragments; Proprotein Convertase 1; Reactive Oxygen Species; Signal Transduction; Trans-Activators; Transcription Factor RelA | 2015 |
Regulation of Granulocyte Colony-Stimulating Factor and Its Receptor in Skeletal Muscle is Dependent Upon the Type of Inflammatory Stimulus.
Topics: Acetylcysteine; Adult; Antioxidants; Chemokine CCL2; Exercise; Granulocyte Colony-Stimulating Factor; Humans; Inflammation; Interleukin-6; Lipopolysaccharides; Male; Muscle, Skeletal; Myoblasts; Neutrophils; Receptors, Granulocyte Colony-Stimulating Factor; RNA, Messenger; Tumor Necrosis Factor-alpha; Young Adult | 2015 |
Development and preclinical evaluation of a new galactomannan-based dressing with antioxidant properties for wound healing.
Topics: Acetylcysteine; Animals; Antioxidants; Bandages; Curcumin; Cytokines; Fibroblasts; Galactans; Galactose; Humans; Inflammation; Irritants; Mannans; Materials Testing; Oxidative Stress; Plant Gums; Reactive Oxygen Species; Sus scrofa; Wound Healing | 2015 |
House dust mite allergen Der f 1 induces IL-8 in human basophilic cells via ROS-ERK and p38 signal pathways.
Topics: Acetylcysteine; Antigens, Dermatophagoides; Arthropod Proteins; Basophils; Cell Line, Tumor; Cloning, Molecular; Cysteine Endopeptidases; Extracellular Signal-Regulated MAP Kinases; Humans; Immunoglobulin E; Inflammation; Interleukin-8; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Reactive Oxygen Species; RNA, Messenger; Signal Transduction | 2015 |
Kallistatin protects against sepsis-related acute lung injury via inhibiting inflammation and apoptosis.
Topics: Acetylcysteine; Acute Lung Injury; Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Cell Line, Tumor; Down-Regulation; Epithelial Cells; Fas Ligand Protein; fas Receptor; Humans; Inflammation; Lipopolysaccharides; Lung; Mice; NF-kappa B; Reactive Oxygen Species; Respiratory Distress Syndrome; Sepsis; Serpins; Signal Transduction | 2015 |
Effects of ROS-relative NF-κB signaling on high glucose-induced TLR4 and MCP-1 expression in podocyte injury.
Topics: Acetylcysteine; Animals; Cell Line, Transformed; Chemokine CCL2; Gene Expression Regulation; Glucose; Inflammation; Mice; NF-kappa B; Podocytes; Pyrrolidines; Reactive Oxygen Species; Signal Transduction; Thiocarbamates; Toll-Like Receptor 4 | 2015 |
Hypoxia Potentiates Palmitate-induced Pro-inflammatory Activation of Primary Human Macrophages.
Topics: Acetylcysteine; Adipocytes; Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Hypoxia; Cells, Cultured; Culture Media, Conditioned; Cytokines; Dual-Specificity Phosphatases; Endoplasmic Reticulum Stress; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Inflammation Mediators; Macrophages; Mice, Inbred C57BL; Mitochondria; Mitogen-Activated Protein Kinase Phosphatases; Mitogen-Activated Protein Kinases; NF-kappa B; Organophosphorus Compounds; Oxygen; Palmitates; Phosphorylation; Piperidines; Reactive Oxygen Species; Signal Transduction | 2016 |
High Glucose and Lipopolysaccharide Prime NLRP3 Inflammasome via ROS/TXNIP Pathway in Mesangial Cells.
Topics: Acetylcysteine; Animals; Blood Glucose; Carrier Proteins; Caspase 1; Cell Cycle Proteins; Glucose; Immunohistochemistry; Inflammasomes; Inflammation; Interleukin-1beta; Lipopolysaccharides; Male; Mesangial Cells; NLR Family, Pyrin Domain-Containing 3 Protein; Random Allocation; Rats; Reactive Oxygen Species; Signal Transduction | 2016 |
Astaxanthin alleviates oxidative stress insults-related derangements in human vascular endothelial cells exposed to glucose fluctuations.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Glucose; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Mitogen-Activated Protein Kinases; NADPH Oxidases; Nitric Oxide Synthase Type III; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Reactive Oxygen Species; Transcription Factors; Xanthophylls | 2016 |
Soyasaponin Bb inhibits the recruitment of toll-like receptor 4 (TLR4) into lipid rafts and its signaling pathway by suppressing the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase-dependent generation of reactive oxygen species.
Topics: Acetylcysteine; Adaptor Proteins, Vesicular Transport; Animals; ATPases Associated with Diverse Cellular Activities; DNA Helicases; Inflammation; Lipopolysaccharides; Macrophages; Membrane Microdomains; Mice; Myeloid Differentiation Factor 88; NADPH Oxidases; NF-kappa B; Onium Compounds; RAW 264.7 Cells; Reactive Oxygen Species; Receptors, Immunologic; Saponins; Signal Transduction; Toll-Like Receptor 4 | 2016 |
Hyperoxia induces inflammation and regulates cytokine production in alveolar epithelium through TLR2/4-NF-κB-dependent mechanism.
Topics: Acetylcysteine; Cell Line, Tumor; Cytokines; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Hyperoxia; Inflammation; NF-kappa B; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Respiratory Mucosa; RNA, Messenger; Toll-Like Receptor 2; Toll-Like Receptor 4 | 2016 |
A multidrug cocktail approach attenuates ischemic-type biliary lesions in liver transplantation from non-heart-beating donors.
Topics: Acetylcysteine; Animals; Biliary Tract Diseases; Drug Therapy, Combination; Epithelial Cells; Epoprostenol; Female; Hemin; Hepatocytes; Humans; Inflammation; Ischemia; Kupffer Cells; Liver; Liver Failure; Liver Transplantation; Models, Theoretical; Organ Preservation; Reactive Oxygen Species; Reoperation; Reperfusion Injury; Streptokinase; Swine; Taurochenodeoxycholic Acid; Thiazolidinediones; Tissue Donors; Warm Ischemia | 2016 |
Resveratrol attenuates monocyte-to-macrophage differentiation and associated inflammation via modulation of intracellular GSH homeostasis: Relevance in atherosclerosis.
Topics: Acetylcysteine; AMP-Activated Protein Kinases; Animals; Antioxidants; Apolipoproteins E; Atherosclerosis; Buthionine Sulfoximine; Cell Differentiation; Glutathione; Homeostasis; Humans; Inflammation; Macrophages; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Monocytes; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate | 2016 |
Differential Action between Schisandrin A and Schisandrin B in Eliciting an Anti-Inflammatory Action: The Depletion of Reduced Glutathione and the Induction of an Antioxidant Response.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Antioxidants; Concanavalin A; Cyclooctanes; Cytokines; Edema; Enzyme-Linked Immunosorbent Assay; Female; Glutathione; Glutathione Transferase; Inflammation; Lignans; Lipopolysaccharides; Mice; Mice, Inbred ICR; Polycyclic Compounds; RAW 264.7 Cells | 2016 |
Molecular Mechanism Underlying Pathogenesis of Lewisite-Induced Cutaneous Blistering and Inflammation: Chemical Chaperones as Potential Novel Antidotes.
Topics: Acetylcysteine; Animals; Antidotes; Antioxidants; Arsenicals; Blister; Chemical Warfare Agents; Disease Models, Animal; Female; Humans; Inflammation; Keratinocytes; Male; Mice; Mice, Hairless; Mice, Inbred C57BL; Molecular Chaperones; Patched-1 Receptor; Phenylbutyrates; Reactive Oxygen Species; Signal Transduction | 2016 |
N-acetylcysteine attenuates lipopolysaccharide-induced impairment in lamination of Ctip2-and Tbr1- expressing cortical neurons in the developing rat fetal brain.
Topics: Acetylcysteine; Animals; Brain; Fetal Development; Gene Expression Regulation, Developmental; Humans; Inflammation; Lipopolysaccharides; Male; Matrix Attachment Region Binding Proteins; Nerve Tissue Proteins; Neurons; Oxidative Stress; Rats; Repressor Proteins; T-Box Domain Proteins; Transcription Factors; Tumor Suppressor Proteins | 2016 |
[Effect of chronic intermittent hypoxia on the expression of CXC chemokine ligand-10 in rat liver and the interventional effect of N-acetylcysteine].
Topics: Acetylcysteine; Animals; Chemokine CXCL10; Fatty Liver; Hypoxia; Inflammation; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2016 |
Pre-Transplantation Blockade of TNF-α-Mediated Oxygen Species Accumulation Protects Hematopoietic Stem Cells.
Topics: Acetylcysteine; Animals; Bone Marrow; Cellular Microenvironment; Cytoprotection; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Indicators and Reagents; Inflammation; Mice, Inbred C57BL; Reactive Oxygen Species; Time Factors; Tumor Necrosis Factor-alpha | 2017 |
Apoptosis of Endothelial Cells by 13-HPODE Contributes to Impairment of Endothelial Barrier Integrity.
Topics: Acetylcysteine; Animals; Apoptosis; Cattle; Cells, Cultured; Endothelial Cells; Humans; Inflammation; Leukocytes, Mononuclear; Linoleic Acids; Lipid Peroxides; Mammary Glands, Human; Oxylipins; Streptococcus | 2016 |
"Inflamm-aging" influences immune cell survival factors in human bone marrow.
Topics: Acetylcysteine; Aging; Animals; Ascorbic Acid; Bone Marrow Cells; CD8-Positive T-Lymphocytes; Cell Survival; Cells, Cultured; Cytokines; Free Radical Scavengers; Humans; Immunologic Memory; Immunosenescence; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Reactive Oxygen Species; Superoxide Dismutase-1 | 2017 |
Premature senescence of endothelial cells upon chronic exposure to TNFα can be prevented by N-acetyl cysteine and plumericin.
Topics: Acetylcysteine; Cell Cycle Checkpoints; Cell Proliferation; Cellular Senescence; Endothelial Cells; Free Radical Scavengers; Humans; Inflammation; NF-kappa B; Phenotype; Reactive Oxygen Species; Signal Transduction; Tumor Necrosis Factor-alpha | 2017 |
Arginase-I enhances vascular endothelial inflammation and senescence through eNOS-uncoupling.
Topics: Acetylcysteine; Adenoviridae; Animals; Arginase; beta-Galactosidase; Cell Line, Tumor; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Endothelium, Vascular; Free Radical Scavengers; Genetic Vectors; Human Umbilical Vein Endothelial Cells; Humans; Immunoblotting; Inflammation; Intercellular Adhesion Molecule-1; Mice; Nitric Oxide Synthase Type III; Transfection; Tumor Suppressor Protein p53; Vascular Cell Adhesion Molecule-1 | 2017 |
Modulation of the Redox Expression and Inflammation Response in the Critically Ill Polytrauma Patient with Thoracic Injury. Statistical Correlations between Antioxidant Therapy.
Topics: Abbreviated Injury Scale; Acetylcysteine; Adult; Aged; Antioxidants; Ascorbic Acid; Critical Illness; Female; Humans; Incidence; Inflammation; Injury Severity Score; Length of Stay; Male; Middle Aged; Multiple Organ Failure; Multiple Trauma; Oxidation-Reduction; Oxidative Stress; Respiration, Artificial; Retrospective Studies; Sepsis; Thiamine; Thoracic Injuries | 2016 |
Psoriasis-like inflammation leads to renal dysfunction via upregulation of NADPH oxidases and inducible nitric oxide synthase.
Topics: Acetylcysteine; Aminoquinolines; Animals; Antioxidants; Buthionine Sulfoximine; Disease Models, Animal; Humans; Imiquimod; Inflammation; Kidney; Kidney Diseases; Male; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Nitric Oxide Synthase Type II; Oxidative Stress; Psoriasis | 2017 |
Topics: Acetylcysteine; Animals; Apoptosis; Bacterial Toxins; Caspase 3; Cell Line, Tumor; Colitis; Colon; Down-Regulation; Enterotoxins; Guinea Pigs; Inflammation; Neurons; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species; rho GTP-Binding Proteins; Up-Regulation | 2017 |
N-acetylcysteine Prevents Alcohol Related Neuroinflammation in Rats.
Topics: Acetylcysteine; Alcohol Drinking; Animals; Anti-Inflammatory Agents; Brain; Ethanol; Inflammation; Inflammation Mediators; Male; Rats; Rats, Wistar | 2017 |
Attenuation of lipopolysaccharide-induced inflammatory response and phospholipids metabolism at the feto-maternal interface by N-acetyl cysteine.
Topics: Acetylcysteine; Animals; Cyclooxygenase 2; DNA Primers; Female; Immunoblotting; Immunoenzyme Techniques; Inflammation; Lipid Peroxidation; Lipopolysaccharides; Malondialdehyde; Maternal-Fetal Exchange; Phospholipids; Placenta; Pregnancy; Rats; Reverse Transcriptase Polymerase Chain Reaction | 2008 |
NO scavenging by 3-hydroxyanthranilic acid and 3-hydroxykynurenine: N-nitrosation leads via oxadiazoles to o-quinone diazides.
Topics: 3-Hydroxyanthranilic Acid; Acetylcysteine; Aminophenols; Chromatography, Thin Layer; Diazonium Compounds; Free Radical Scavengers; Hydrazines; Inflammation; Kynurenine; Magnetic Resonance Imaging; Mass Spectrometry; Nitric Oxide; Nitrites; Nitrosation; Nuclear Magnetic Resonance, Biomolecular; ortho-Aminobenzoates; Oxadiazoles; Quinones; Tryptophan | 2008 |
Cigarette smoke-induced expression of heme oxygenase-1 in human lung fibroblasts is regulated by intracellular glutathione.
Topics: Acetylcysteine; Cell Death; Fibroblasts; Gene Expression Regulation, Enzymologic; Glutathione; Heme Oxygenase-1; Humans; Inflammation; Lung; NF-E2 Transcription Factor; NF-E2-Related Factor 2; Pulmonary Disease, Chronic Obstructive; Smoke | 2008 |
The effects of oxidative stress induced by prolonged low-dose diesel exhaust particle exposure on the generation of allergic airway inflammation differ between BALB/c and C57BL/6 mice.
Topics: Acetylcysteine; Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Cytokines; Eosinophils; Female; Goblet Cells; Immunoglobulin E; Immunoglobulin G; Inflammation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Oxidative Stress; Particulate Matter; Respiratory Hypersensitivity; Vehicle Emissions | 2009 |
N-acetylcysteine attenuates progression of liver pathology in a rat model of nonalcoholic steatohepatitis.
Topics: Acetylcysteine; Animals; Autoantibodies; Disease Models, Animal; Energy Intake; Fatty Liver; Glutathione; Inflammation; Liver; Liver Function Tests; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Triglycerides | 2008 |
Cigarette smoke extract induces thymic stromal lymphopoietin expression, leading to T(H)2-type immune responses and airway inflammation.
Topics: Acetylcysteine; Administration, Intranasal; Animals; Asthma; Complex Mixtures; Cytokines; Female; Free Radical Scavengers; Gene Expression Regulation; Humans; Inflammation; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Oxidative Stress; Receptors, Tumor Necrosis Factor, Type I; Risk Factors; Th2 Cells; Thymic Stromal Lymphopoietin; Tobacco Smoke Pollution | 2008 |
Prophylactic maternal n-acetylcysteine before lipopolysaccharide suppresses fetal inflammatory cytokine responses.
Topics: Acetylcysteine; Animals; Cytokines; Female; Fetal Diseases; Inflammation; Interleukin-10; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Pregnancy; Rats; Rats, Sprague-Dawley | 2009 |
Oxidative stress augments toll-like receptor 8 mediated neutrophilic responses in healthy subjects.
Topics: Acetylcysteine; Chemotaxis, Leukocyte; Cytokines; Flow Cytometry; Humans; Hydrogen Peroxide; Imidazoles; Inflammation; Interleukin-8; Neutrophils; Oxidative Stress; Pancreatic Elastase; Phosphorylation; Reference Values; Signal Transduction; Toll-Like Receptor 7; Toll-Like Receptor 8; Transcription Factor RelA; Virus Diseases | 2009 |
Serine protease inhibitor aprotinin ameliorates renal injury in a rat model of ischemia-perfusion injury.
Topics: Acetylcysteine; Animals; Aprotinin; Glutathione; Inflammation; Kidney; Kidney Tubules; Malondialdehyde; Necrosis; Nephrectomy; Rats; Rats, Wistar; Reperfusion Injury; Serine Proteinase Inhibitors | 2009 |
Alteration of Toll-like receptor 4 activation by 4-hydroxy-2-nonenal mediated by the suppression of receptor homodimerization.
Topics: Acetylcysteine; Aldehydes; Animals; Cell Line; Chemokine CCL5; Chemokine CXCL10; Dimerization; Dithiothreitol; Humans; Immunoblotting; Inflammation; Interferon-beta; Lipopolysaccharides; Mice; Phagocytosis; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2009 |
Altered gene expression in neural crest cells exposed to ethanol in vitro.
Topics: Acetylcysteine; Animals; Apoptosis; Cell Movement; Central Nervous System Depressants; Ethanol; Free Radical Scavengers; Gene Expression Regulation, Developmental; Immunohistochemistry; In Vitro Techniques; Inflammation; Metabolism; Neural Crest; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2009 |
Effect of N-acetylcysteine on the early expression of inflammatory markers in the retina and plasma of diabetic rats.
Topics: Acetylcysteine; Animals; Biomarkers; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Dinoprost; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique, Indirect; Free Radical Scavengers; Immunoenzyme Techniques; Inflammation; Isoprostanes; Macrophages; Male; Microglia; Oxidative Stress; Pericytes; Rats; Rats, Wistar; Retina; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2009 |
Increased oxidative stress in the airway and development of allergic inflammation in a mouse model of asthma.
Topics: Acetylcysteine; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cells, Cultured; Disease Models, Animal; Female; Free Radical Scavengers; Glutathione; Immunization; Inflammation; Lung; Mice; Mice, Inbred BALB C; Mucins; Ovalbumin; Oxidative Stress; Respiratory Mucosa | 2009 |
Effects of reactive oxygen species scavenger on the protective action of 100% oxygen treatment against sterile inflammation in mice.
Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Cytokines; Free Radical Scavengers; Heart; Inflammation; Kidney; Liver; Lung; Male; Mice; Multiple Organ Failure; Myocardium; Oxygen; Reactive Oxygen Species; Sepsis; Thiourea; Zymosan | 2010 |
N-acetylcysteine improves early cardiac isograft function in a rat heterotopic transplantation model.
Topics: Acetylcysteine; Animals; Antioxidants; Echocardiography; Heart Transplantation; Inflammation; Infusions, Intravenous; Interleukin-1; L-Lactate Dehydrogenase; Models, Animal; Oxidative Stress; Rats; Rats, Inbred Lew; Transplantation, Heterotopic; Transplantation, Isogeneic; Tumor Necrosis Factor-alpha | 2009 |
N-acetylcysteine attenuates cerebral complications of non-acetaminophen-induced acute liver failure in mice: antioxidant and anti-inflammatory mechanisms.
Topics: Acetaminophen; Acetylcysteine; Animals; Antioxidants; Azoxymethane; Brain Edema; Carcinogens; Cytokines; Disease Models, Animal; Hepatic Encephalopathy; Inflammation; Inflammation Mediators; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Oxidative Stress | 2010 |
Ablation of the transcription factor Nrf2 promotes ischemia-induced neovascularization by enhancing the inflammatory response.
Topics: Acetylcysteine; Angiogenic Proteins; Animals; Antioxidants; Capillaries; Cell Adhesion Molecules; Chemokine CCL2; Cyclooxygenase 2; Disease Models, Animal; Endothelial Cells; Femoral Artery; Glutathione; Heme Oxygenase-1; Hindlimb; Inflammation; Inflammation Mediators; Ischemia; Laser-Doppler Flowmetry; Ligation; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Skeletal; Neovascularization, Physiologic; NF-E2-Related Factor 2; Oxidative Stress; Peroxiredoxins; Regional Blood Flow; RNA, Messenger; Superoxides; Thioredoxins; Time Factors; Tumor Necrosis Factor-alpha | 2010 |
Anthrax lethal toxin activates the inflammasome in sensitive rat macrophages.
Topics: Acetylcysteine; Adaptor Proteins, Signal Transducing; Animals; Antigens, Bacterial; Apoptosis Regulatory Proteins; Bacterial Toxins; Caspase 1; Cell Death; Cell Line; Cysteine Proteinase Inhibitors; Female; Inflammation; Macrophages; Proteasome Endopeptidase Complex; Rats | 2010 |
More than antioxidant: N-acetyl-L-cysteine in a murine model of endometriosis.
Topics: Acetylcysteine; Animals; Antioxidants; Cell Differentiation; Cell Movement; Cell Proliferation; Cytostatic Agents; Disease Models, Animal; Drug Evaluation, Preclinical; Endometriosis; Female; Inflammation; Inflammation Mediators; Mice; Mice, Inbred BALB C; Peritoneal Diseases | 2010 |
Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition.
Topics: Acetylcysteine; Adaptor Proteins, Signal Transducing; Adolescent; Adult; Animals; Antioxidants; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Cell Line; Cystamine; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Sodium Channels; GTP-Binding Proteins; Heat-Shock Proteins; Humans; Inflammation; Membrane Proteins; Mice; Mice, Inbred CFTR; Mice, Inbred Strains; Mice, Transgenic; Microtubule-Associated Proteins; Models, Biological; Nasal Polyps; Organometallic Compounds; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Binding; Protein Glutamine gamma Glutamyltransferase 2; Protein Transport; Reactive Oxygen Species; Respiratory Mucosa; Salicylates; Sequestosome-1 Protein; Small Ubiquitin-Related Modifier Proteins; Transglutaminases; Young Adult | 2010 |
Evaluation of thiol-based antioxidant therapeutics in cystic fibrosis sputum: Focus on myeloperoxidase.
Topics: Acetylcysteine; Adult; C-Reactive Protein; Cells, Cultured; Chloramines; Cystic Fibrosis; Female; Glutathione; Humans; Inflammation; Lung; Male; Middle Aged; Neutrophils; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Peroxidase; Sputum; Young Adult | 2011 |
Reactive oxygen species mediate human hepatocyte injury during hypoxia/reoxygenation.
Topics: Acetylcysteine; Annexin A5; Antioxidants; Apoptosis; Female; Flow Cytometry; Hepatocytes; Humans; Hypoxia; Inflammation; Kupffer Cells; Liver; Liver Diseases; Male; Mitochondria; Models, Biological; NADPH Oxidases; Reactive Oxygen Species; Reperfusion Injury; Young Adult | 2010 |
Effects of histidine and N-acetylcysteine on diclofenac-induced anti-inflammatory response in acute inflammation in rats.
Topics: Acetylcysteine; Acute Disease; Animals; Carrageenan; Cyclooxygenase Inhibitors; Diclofenac; Drug Synergism; Edema; Free Radical Scavengers; Hindlimb; Histidine; Inflammation; Injections; Male; Neutrophil Infiltration; Rats; Rats, Wistar | 2010 |
Aggravation of bleomycin-induced pulmonary inflammation and fibrosis in mice lacking peroxiredoxin I.
Topics: Acetylcysteine; Animals; Antibiotics, Antineoplastic; Apoptosis; Bleomycin; Bronchoalveolar Lavage; Cells, Cultured; Dinoprost; Free Radical Scavengers; Inflammation; Lung; Macrophage Migration-Inhibitory Factors; Mice; Mice, Transgenic; Oxidative Stress; Peroxiredoxins; Pulmonary Fibrosis | 2011 |
UVB-induced DNA damage, generation of reactive oxygen species, and inflammation are effectively attenuated by the flavonoid luteolin in vitro and in vivo.
Topics: Acetylcysteine; Antioxidants; Cell Line; Chromans; Cyclooxygenase 2; Cytoprotection; Dinoprostone; DNA Damage; Erythema; Extracellular Signal-Regulated MAP Kinases; Fluoresceins; Gene Expression; Humans; Inflammation; Inhibitory Concentration 50; Keratinocytes; Luteolin; Organ Culture Techniques; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pyrimidine Dimers; Reactive Oxygen Species; Skin; Skin Neoplasms; Ultraviolet Rays | 2011 |
N-acetyl-cysteine (NAC) attenuates LPS-induced maternal and amniotic fluid oxidative stress and inflammatory responses in the preterm gestation.
Topics: Acetylcysteine; Amniotic Fluid; Animals; Cytokines; Female; Inflammation; Lipopolysaccharides; Oxidative Stress; Pregnancy; Rats; Rats, Sprague-Dawley | 2011 |
Anti-inflammatory properties of N-acetylcysteine on lipopolysaccharide-activated macrophages.
Topics: Acetylcysteine; Animals; Cell Line; Cytokines; Humans; Immunity, Innate; Inflammation; Lipopolysaccharides; Macrophages; Oxidation-Reduction; Reactive Oxygen Species | 2011 |
N-acetylcysteine attenuates leukocytic inflammation and microvascular perfusion failure in critically ischemic random pattern flaps.
Topics: Acetylcysteine; Animals; Apoptosis; Arterioles; Capillaries; Cell Adhesion; Dermatologic Surgical Procedures; Inflammation; Ischemia; Leukocyte Rolling; Leukocytes; Mice; Mice, Inbred C57BL; Microcirculation; Microvessels; Necrosis; Regional Blood Flow; Surgical Flaps; Vasodilation | 2011 |
The effect of antioxidants on the production of pro-inflammatory cytokines and orthodontic tooth movement.
Topics: Acetylcysteine; Animals; Antioxidants; Cells, Cultured; Fibroblasts; Humans; Hypoxia; Inflammation; Inflammation Mediators; Interleukin-1beta; Male; Molar; Periodontal Ligament; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Stress, Mechanical; Tooth Mobility; Tumor Necrosis Factor-alpha; Up-Regulation | 2011 |
Treatment of ricin A-chain-induced hepatotoxicity with liposome-encapsulated N-acetylcysteine.
Topics: Acetylcysteine; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Chemical Warfare Agents; Inflammation; Lipid Peroxidation; Liposomes; Male; Rats; Rats, Sprague-Dawley; Ricin | 2011 |
PGC-1-related coactivator (PRC), a sensor of metabolic stress, orchestrates a redox-sensitive program of inflammatory gene expression.
Topics: Acetylcysteine; Adenosine Triphosphate; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Free Radical Scavengers; Gene Expression Regulation; HEK293 Cells; Humans; Inflammation; Nuclear Respiratory Factor 1; Oxidation-Reduction; Proton Ionophores; Stress, Physiological; Transcription Factors | 2011 |
Antioxidant N-acetyl cysteine reverses cigarette smoke-induced myocardial infarction by inhibiting inflammation and oxidative stress in a rat model.
Topics: Acetylcysteine; Animals; Antioxidants; Base Sequence; Cotinine; Cytokines; Disease Models, Animal; DNA Primers; Echocardiography; Inflammation; Myocardial Infarction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Smoke | 2012 |
N-acetylcysteine reduces inflammation in the small intestine by regulating redox, EGF and TLR4 signaling.
Topics: Acetylcysteine; Animals; Dietary Supplements; Epidermal Growth Factor; Female; Inflammation; Intestine, Small; Lipopolysaccharides; Oxidation-Reduction; Real-Time Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Swine; Toll-Like Receptor 4 | 2013 |
Lipopolysaccharide-induced neuroinflammation leads to the accumulation of ubiquitinated proteins and increases susceptibility to neurodegeneration induced by proteasome inhibition in rat hippocampus.
Topics: Acetylcysteine; Aging; Animals; Drug Synergism; Hippocampus; Inflammation; Lipopolysaccharides; Male; Nerve Degeneration; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Rats; Rats, Wistar; Ubiquitination | 2012 |
Free radical-operated proteotoxic stress in macrophages primed with lipopolysaccharide.
Topics: Acetylcysteine; Animals; Blotting, Western; Cell Death; Cells, Cultured; Cyclic N-Oxides; Free Radical Scavengers; Free Radicals; Immunoenzyme Techniques; Immunoprecipitation; Inflammation; Lipopolysaccharides; Macrophages; Mice; Nitrogen Oxides; Oxidation-Reduction; Oxidative Stress; Protein Carbonylation; Proteins; Reactive Oxygen Species; Spin Labels; Spin Trapping; Tandem Mass Spectrometry | 2012 |
N-acetylcysteine treatment reduces TNF-α levels and myonecrosis in diaphragm muscle of mdx mice.
Topics: Acetylcysteine; Animals; Antioxidants; Diaphragm; Dystrophin; Inflammation; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle, Skeletal; Necrosis; Tumor Necrosis Factor-alpha | 2013 |
Fructose-1,6-bisphosphate and N-acetylcysteine attenuate the formation of advanced oxidation protein products, a new class of inflammatory mediators, in vitro.
Topics: Acetylcysteine; Advanced Oxidation Protein Products; Biomarkers; Fructosediphosphates; Humans; Inflammation; Inflammation Mediators; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Serum Albumin | 2012 |
Inflammation-induced dysfunction of the low-density lipoprotein receptor-related protein-1 at the blood-brain barrier: protection by the antioxidant N-acetylcysteine.
Topics: Acetylcysteine; Algorithms; alpha-Macroglobulins; Amyloid beta-Peptides; Animals; Antioxidants; Blood-Brain Barrier; Calcium Channel Blockers; Cerebral Cortex; Chemokines; Cytokines; Glutathione; Hippocampus; Inflammation; Lipopolysaccharides; Low Density Lipoprotein Receptor-Related Protein-1; Male; Mice; Oxidative Stress; Protein Carbonylation; Receptors, LDL; Serum Albumin; Tumor Suppressor Proteins; Verapamil | 2012 |
Innate immune activation by inhaled lipopolysaccharide, independent of oxidative stress, exacerbates silica-induced pulmonary fibrosis in mice.
Topics: Acetylcysteine; Administration, Inhalation; Animals; Bronchoalveolar Lavage; Cytokines; Drinking Water; Hydroxyproline; Immunity, Innate; Inflammation; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Protein Carbonylation; Pulmonary Fibrosis; Silicon Dioxide | 2012 |
Neuroprotective effects of N-acetyl-cysteine and acetyl-L-carnitine after spinal cord injury in adult rats.
Topics: Acetylcarnitine; Acetylcysteine; Animals; Antioxidants; Astrocytes; Female; Inflammation; Microglia; Microtubule-Associated Proteins; Models, Biological; Motor Neurons; Neuroglia; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries | 2012 |
Proteasome inhibition decreases inflammation in human endothelial cells exposed to lipopolysaccharide.
Topics: Acetylcysteine; Electrophoresis, Gel, Two-Dimensional; Enzyme-Linked Immunosorbent Assay; GTP-Binding Protein beta Subunits; Heterogeneous-Nuclear Ribonucleoprotein K; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Lipopolysaccharides; Oxidative Stress; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Ribonucleoproteins; Up-Regulation | 2012 |
Dietary supplementation with N-acetyl cysteine, α-tocopherol and α-lipoic acid reduces the extent of oxidative stress and proinflammatory state in aged rat brain.
Topics: Acetylcysteine; alpha-Tocopherol; Animals; Brain; Cell Nucleus; Cytokines; Dietary Supplements; Enzyme-Linked Immunosorbent Assay; Inflammation; Mitochondria; NF-kappa B; Oxidative Stress; Rats; Reactive Oxygen Species; Thioctic Acid | 2012 |
Inflammation-mediated abrogation of androgen signaling: an in vitro model of prostate cell inflammation.
Topics: Acetylcysteine; Androgens; Antioxidants; Apoptosis; Cell Differentiation; Cell Line, Tumor; Down-Regulation; Glutathione Peroxidase; Homeodomain Proteins; Humans; I-kappa B Proteins; Inflammation; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Kallikreins; Lysine; Macrophages; Male; Matrix Metalloproteinase 9; NF-kappa B; Phosphorylation; Prostate-Specific Antigen; Prostatic Neoplasms; Prostatitis; Proto-Oncogene Proteins c-mdm2; Reactive Oxygen Species; Receptors, Androgen; Signal Transduction; Transcription Factors; Transcriptional Activation; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; U937 Cells; Up-Regulation | 2014 |
Sevoflurane combined with ATP activates caspase-1 and triggers caspase-1-dependent pyroptosis in murine J774 macrophages.
Topics: Acetylcysteine; Adenosine Triphosphate; Amino Acid Chloromethyl Ketones; Animals; Caspase 1; Caspase Inhibitors; Cell Death; Cell Line; Cell Survival; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Free Radical Scavengers; Inflammation; Macrophages; Methyl Ethers; Mice; Onium Compounds; Platelet Aggregation Inhibitors; Reactive Oxygen Species; Sevoflurane | 2013 |
Nickel-regulated heart rate variability: the roles of oxidative stress and inflammation.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Antioxidants; Celecoxib; Heart Rate; Inflammation; Injections, Intraperitoneal; Male; Models, Theoretical; Nickel; Oxidative Stress; Pyrazoles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sulfonamides | 2013 |
N-acetylcysteine administration is associated with reduced activation of NF-kB and preserves lung dendritic cells function in a zymosan-induced generalized inflammation model.
Topics: Acetylcysteine; Animals; Apoptosis; Cytokines; Dendritic Cells; Disease Models, Animal; Enzyme Activation; Histocompatibility Antigens Class II; Inflammation; Lung; Male; Mice; NF-kappa B; Receptors, CCR5; Receptors, CCR7; Respiratory Function Tests; RNA, Messenger; Zymosan | 2013 |
Activation of a PGC-1-related coactivator (PRC)-dependent inflammatory stress program linked to apoptosis and premature senescence.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Camptothecin; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Line, Tumor; Cell Survival; Cellular Senescence; Cornified Envelope Proline-Rich Proteins; Gene Expression; Gene Knockdown Techniques; Histamine H1 Antagonists; Humans; Inflammation; Irinotecan; Kinetics; Meclizine; Oxidants; Oxidative Stress; Proto-Oncogene Proteins c-myc; Proton Ionophores; RNA, Small Interfering; Topoisomerase I Inhibitors; Transcription Factors; Transcriptional Activation; Vitamin K 3 | 2013 |
Bleomycin-induced pulmonary fibrosis is attenuated in gamma-glutamyl transpeptidase-deficient mice.
Topics: Acetylcysteine; Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen; Cysteine; Disease Models, Animal; gamma-Glutamyltransferase; Glutathione; Inflammation; Leukocyte Count; Matrix Metalloproteinase 9; Mice; Mice, Inbred Strains; Neutrophils; Pulmonary Fibrosis; Severity of Illness Index; Time Factors | 2003 |
Protective effect of N-acetylcysteine against fetal death and preterm labor induced by maternal inflammation.
Topics: Acetylcysteine; Animals; Female; Fetal Death; Gestational Age; Glutathione; Inflammation; Kinetics; Lipopolysaccharides; Liver; Mice; Mice, Inbred C57BL; Obstetric Labor, Premature; Oxidation-Reduction; Pregnancy; Pregnancy Complications | 2003 |
Effect of N-acetylcysteine on microcirculation of mucosa in rat ileum in a model of intestinal inflammation.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Free Radical Scavengers; Indomethacin; Inflammation; Intestinal Mucosa; Intestine, Small; Male; Microcirculation; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Regional Blood Flow; Statistics, Nonparametric | 2003 |
An angiogenic role for the human peptide antibiotic LL-37/hCAP-18.
Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Apoptosis; Blotting, Western; Calcium; Cathelicidins; Cell Division; Cells, Cultured; Collagen; Cricetinae; Drug Combinations; Endothelium, Vascular; Enzyme Inhibitors; Humans; Indoles; Inflammation; Ischemia; Laminin; Maleimides; Mesocricetus; Mice; Neovascularization, Physiologic; NF-kappa B; Peptides; Prodrugs; Proteoglycans; Rabbits; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Lipoxin; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Wound Healing | 2003 |
Effect of the proteasome inhibitor MLN519 on the expression of inflammatory molecules following middle cerebral artery occlusion and reperfusion in the rat.
Topics: Acetylcysteine; Animals; Cell Adhesion Molecules; Cysteine Endopeptidases; Cytokines; DNA; Gene Expression Regulation; Immunohistochemistry; Infarction, Middle Cerebral Artery; Inflammation; Kinetics; Male; Middle Cerebral Artery; Multienzyme Complexes; Neuroprotective Agents; NF-kappa B; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2003 |
Delayed treatment of ischemia/reperfusion brain injury: extended therapeutic window with the proteosome inhibitor MLN519.
Topics: Acetylcysteine; Animals; Biomarkers; Brain Chemistry; Brain Ischemia; Chemotherapy, Adjuvant; Disease Models, Animal; E-Selectin; Fibrinolytic Agents; Infarction, Middle Cerebral Artery; Inflammation; Intercellular Adhesion Molecule-1; Male; Neuroprotective Agents; Neutrophil Infiltration; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tumor Necrosis Factor-alpha | 2004 |
Administration of N-acetylcysteine after focal cerebral ischemia protects brain and reduces inflammation in a rat model of experimental stroke.
Topics: Acetylcysteine; Animals; Brain Ischemia; Cerebrovascular Circulation; Cytokines; Disease Models, Animal; DNA Fragmentation; Dose-Response Relationship, Drug; Ectodysplasins; Free Radical Scavengers; Glial Fibrillary Acidic Protein; Glutathione; Immunohistochemistry; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Inflammation; Ischemic Attack, Transient; Male; Membrane Proteins; Neurologic Examination; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Time Factors | 2004 |
Characterization and modulation of the transferrin receptor on brain capillary endothelial cells.
Topics: Acetylcysteine; Animals; Astrocytes; Capillaries; Cattle; Cells, Cultured; Cerebrovascular Circulation; Deferoxamine; Down-Regulation; Endocytosis; Endothelial Cells; Extracellular Space; Free Radical Scavengers; Inflammation; Iron; Lipopolysaccharides; Receptors, Transferrin; Transferrin; Tyrphostins | 2004 |
A novel role of lactosylceramide in the regulation of lipopolysaccharide/interferon-gamma-mediated inducible nitric oxide synthase gene expression: implications for neuroinflammatory diseases.
Topics: Acetylcysteine; Animals; Antigens, CD; Antioxidants; Apoptosis; Astrocytes; Cells, Cultured; Demyelinating Diseases; Drug Evaluation, Preclinical; Enzyme Induction; Enzyme Inhibitors; Fatty Acids; Female; Gait Disorders, Neurologic; Galactosyltransferases; I-kappa B Proteins; Inflammation; Interferon-gamma; Lactosylceramides; Lipopolysaccharides; Morpholines; Nerve Tissue Proteins; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidation-Reduction; Phosphorylation; Proline; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Signal Transduction; Spinal Cord Injuries; Thiocarbamates; Transfection | 2004 |
The effect of inducible nitric oxide synthase on postoperative adhesion formation in rats.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Enzyme Inhibitors; Female; Fibrosis; Inflammation; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peritoneal Diseases; Peritoneum; Postoperative Complications; Rats; Rats, Wistar; Tissue Adhesions | 2004 |
Protective effect of N-acetylcysteine and deferoxamine on carbon tetrachloride-induced acute hepatic failure in rats.
Topics: Acetylcysteine; Animals; Antioxidants; Carbon Tetrachloride; Deferoxamine; Hydrocarbons; Inflammation; Liver; Liver Failure, Acute; Male; Models, Animal; Necrosis; Oxidative Stress; Rats; Rats, Wistar | 2004 |
The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species.
Topics: 3T3-L1 Cells; 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Adenoviridae; Adipocytes; Animals; Blotting, Northern; Cell Differentiation; Deoxyguanosine; Diabetes Mellitus, Experimental; Dicarboxylic Acid Transporters; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Glucose; Hyperglycemia; Immunoblotting; Inflammation; Insulin; Interleukin-6; Membrane Potentials; Mice; Mitochondria; Oxidative Stress; Oxygen; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Streptozocin; Time Factors; Transcription, Genetic; Up-Regulation | 2005 |
Iron-mediated H2O2 production as a mechanism for cell type-specific inhibition of tumor necrosis factor alpha-induced but not interleukin-1beta-induced IkappaB kinase complex/nuclear factor-kappaB activation.
Topics: Acetylcysteine; Animals; Catalase; Cell Cycle; Cell Line; Cell Nucleus; Cell Separation; Cells, Cultured; Enzyme Activation; Flow Cytometry; G1 Phase; HeLa Cells; HL-60 Cells; HSP90 Heat-Shock Proteins; Humans; Hydrogen Peroxide; I-kappa B Kinase; Inflammation; Interleukin-1; Iron; Jurkat Cells; Mice; Mimosine; Mitogen-Activated Protein Kinase 8; NF-kappa B; NIH 3T3 Cells; p38 Mitogen-Activated Protein Kinases; Protein Binding; Protein Serine-Threonine Kinases; Receptors, Tumor Necrosis Factor, Type I; S Phase; Time Factors; Tumor Necrosis Factor-alpha; U937 Cells | 2005 |
Manganese potentiates in vitro production of proinflammatory cytokines and nitric oxide by microglia through a nuclear factor kappa B-dependent mechanism.
Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cells, Cultured; Chromans; Cytokines; Enzyme Inhibitors; Inflammation; L-Lactate Dehydrogenase; Lipopolysaccharides; Manganese Poisoning; Mice; Microglia; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pentoxifylline; Phosphodiesterase Inhibitors; Serine Proteinase Inhibitors; Tosylphenylalanyl Chloromethyl Ketone | 2005 |
N-Acetylcysteine administered as part of the immediate post-traumatic resuscitation regimen does not significantly influence initiation of inflammatory responses or subsequent endotoxin hyporesponsiveness.
Topics: Acetylcysteine; Animals; Endotoxins; Inflammation; Interleukin-1; Leukocytes; Neutrophils; Norway; Reactive Oxygen Species; Resuscitation; Swine; Tumor Necrosis Factor-alpha; Wounds and Injuries | 2005 |
Mitochondrial Dok-4 recruits Src kinase and regulates NF-kappaB activation in endothelial cells.
Topics: Acetylcysteine; Adaptor Proteins, Signal Transducing; Animals; Blotting, Western; Cattle; Cells, Cultured; Endothelium, Vascular; Ethidium; Gene Deletion; Green Fluorescent Proteins; Immunoprecipitation; Inflammation; Intracellular Signaling Peptides and Proteins; Microscopy, Confocal; Microscopy, Fluorescence; Mitochondria; Models, Biological; Mutation; NF-kappa B; Oxygen Consumption; Phosphoproteins; Plasmids; Protein Binding; Protein Structure, Tertiary; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Signal Transduction; src-Family Kinases; Subcellular Fractions; Time Factors; Transfection; Tumor Necrosis Factor-alpha | 2005 |
Effects of N-acetylcysteine on ethanol-induced hepatotoxicity in rats fed via total enteral nutrition.
Topics: Acetylcysteine; Aldehydes; Animals; Antioxidants; Cattle; Central Nervous System Depressants; Cytochrome P-450 CYP2E1; Cytokines; Cytosol; Enteral Nutrition; Ethanol; Glutathione; Immune System; Immunohistochemistry; Inflammation; Kupffer Cells; Lipid Peroxidation; Lipopolysaccharide Receptors; Lipopolysaccharides; Liver; Lymphotoxin-alpha; Male; Malondialdehyde; Necrosis; Oxidants; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Tumor Necrosis Factor-alpha | 2005 |
Redox regulation of cytokine-mediated inhibition of myelin gene expression in human primary oligodendrocytes.
Topics: Acetylcysteine; Animals; Antioxidants; Cells, Cultured; Cytokines; DNA Primers; Dose-Response Relationship, Drug; Down-Regulation; Encephalomyelitis, Autoimmune, Experimental; Female; Gene Expression Regulation; Humans; Hydrogen Peroxide; Inflammation; Interleukin-1; Mice; Multiple Sclerosis; Myelin Basic Protein; Myelin Proteins; Myelin Proteolipid Protein; Myelin Sheath; Myelin-Associated Glycoprotein; Myelin-Oligodendrocyte Glycoprotein; Neuroglia; Oligodendroglia; Oxidants; Oxidation-Reduction; Phosphoric Diester Hydrolases; Proline; Pyrrolidines; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Sulfhydryl Compounds; Thiocarbamates; Time Factors; Tumor Necrosis Factor-alpha | 2005 |
C-reactive protein induces NF-kappaB activation through intracellular calcium and ROS in human mesangial cells.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; Antioxidants; Blotting, Northern; C-Reactive Protein; Calcium; Cells, Cultured; Chelating Agents; Chemokine CCL2; Dose-Response Relationship, Drug; Egtazic Acid; Electrophoretic Mobility Shift Assay; Gene Expression Regulation; Humans; Inflammation; Mesangial Cells; Microscopy, Confocal; NF-kappa B; Reactive Oxygen Species; Recombinant Proteins; RNA, Messenger; Time Factors | 2005 |
Dietary supplementation of N-acetylcysteine enhances early inflammatory responses during cutaneous wound healing in protein malnourished mice.
Topics: Acetylcysteine; Animals; Antioxidants; Diet, Protein-Restricted; Dietary Supplements; Female; I-kappa B Proteins; Inflammation; Interleukin-1; Mice; Mice, Knockout; NF-KappaB Inhibitor alpha; Protein Deficiency; Reactive Oxygen Species; RNA, Messenger; Skin; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Wound Healing | 2006 |
N-acetylcysteine and deferoxamine reduce pulmonary oxidative stress and inflammation in rats after coal dust exposure.
Topics: Acetylcysteine; Animals; Coal; Deferoxamine; Dust; Free Radicals; Inflammation; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Wistar; Siderophores; Trachea | 2005 |
Key inflammatory signaling pathways are regulated by the proteasome.
Topics: Acetylcysteine; Animals; Cell Survival; Chymotrypsin; Gene Expression Regulation, Enzymologic; Inflammation; Lipopolysaccharides; Macrophages; Mice; Oligonucleotide Array Sequence Analysis; Proteasome Endopeptidase Complex; Shock, Septic; Signal Transduction; Toll-Like Receptor 4 | 2006 |
Proteasome-mediated regulation of CpG DNA- and peptidoglycan-induced cytokines, inflammatory genes, and mitogen-activated protein kinase activation.
Topics: Acetylcysteine; Animals; Cell Line; CpG Islands; Cysteine Proteinase Inhibitors; Cytokines; DNA, Bacterial; Gene Expression Regulation; Inflammation; Macrophages; MAP Kinase Signaling System; Mice; Peptidoglycan; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein-Tyrosine Kinases; Transcription Factor AP-1 | 2006 |
A microarray analysis of the murine macrophage response to infection with Francisella tularensis LVS.
Topics: Acetylcysteine; Animals; Cell Line; Clone Cells; Francisella tularensis; Free Radical Scavengers; Gene Expression Profiling; Glutathione; Inflammation; Macrophages; Mice; Nitric Oxide Synthase Type II; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Time Factors; Tularemia; Tumor Necrosis Factor-alpha | 2006 |
Maternal N-acetylcysteine suppresses fetal inflammatory cytokine responses to maternal lipopolysaccharide.
Topics: Acetylcysteine; Animals; Cytokines; Female; Fetal Diseases; Inflammation; Interleukin-1; Interleukin-10; Interleukin-6; Lipopolysaccharides; NF-kappa B; Pregnancy; Rats; Rats, Sprague-Dawley | 2006 |
Endotoxin induces toll-like receptor 4 expression in vascular smooth muscle cells via NADPH oxidase activation and mitogen-activated protein kinase signaling pathways.
Topics: Acetophenones; Acetylcysteine; Animals; Aorta; Atherosclerosis; Cells, Cultured; Endotoxins; Enzyme Inhibitors; Free Radical Scavengers; Gene Expression Regulation; Humans; Inflammation; Lipopolysaccharides; Mitogen-Activated Protein Kinase Kinases; Muscle, Smooth, Vascular; NADPH Oxidases; Onium Compounds; Rabbits; RNA, Messenger; Signal Transduction; Toll-Like Receptor 4 | 2006 |
Elevated oxidative stress in erythrocytes due to a SOD1 deficiency causes anaemia and triggers autoantibody production.
Topics: Acetylcysteine; Anemia; Animals; Antioxidants; Autoantibodies; Erythrocytes; Inflammation; Mice; Mice, Knockout; Oxidation-Reduction; Oxidative Stress; Phenotype; Superoxide Dismutase; Superoxide Dismutase-1 | 2007 |
Complex N-acetyl-L-cysteine compounds with biometals as self-defense factors of biological system.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Carrageenan; Dose-Response Relationship, Drug; Inflammation; Male; Mice; Physical Endurance; Trace Elements | 2006 |
Essential role of protein kinase C zeta in transducing a motility signal induced by superoxide and a chemotactic peptide, fMLP.
Topics: Acetylcysteine; Animals; Cell Line, Tumor; Cell Movement; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Guanine Nucleotide Dissociation Inhibitors; Humans; Inflammation; Mice; N-Formylmethionine Leucyl-Phenylalanine; Neoplasm Invasiveness; Oxidative Stress; Protein Kinase C; rho GTP-Binding Proteins; rho Guanine Nucleotide Dissociation Inhibitor alpha; rho-Specific Guanine Nucleotide Dissociation Inhibitors; Signal Transduction; Superoxide Dismutase; Superoxides | 2007 |
Wear particles generated from studded tires and pavement induces inflammatory reactions in mouse macrophage cells.
Topics: Acetylcysteine; Androstadienes; Animals; Cell Line; Cell Survival; Cytokines; Deferoxamine; Free Radical Scavengers; Gene Expression; Inflammation; Interleukin-6; Lipid Peroxidation; Macrophages; Mice; Microscopy, Electron, Scanning; Motor Vehicles; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Particulate Matter; Quartz; Reactive Oxygen Species; RNA, Messenger; Silicon Dioxide; Tumor Necrosis Factor-alpha; Wortmannin | 2007 |
Effects of laxative and N-acetylcysteine on mucus accumulation, bacterial load, transit, and inflammation in the cystic fibrosis mouse small intestine.
Topics: Acetylcysteine; Animals; Bacteria; Body Weight; Cathartics; Cystic Fibrosis; Disease Models, Animal; Expectorants; Gastric Emptying; Gastrointestinal Transit; Gene Expression Regulation; Immunity, Innate; Inflammation; Intestine, Small; Mice; Mice, Inbred CFTR; Mucus; Polyethylene Glycols; RNA, Bacterial; RNA, Ribosomal, 16S | 2007 |
N-acetyl cysteine attenuates the inflammatory response in warm ischemic pig lungs.
Topics: Acetylcysteine; Animals; Antioxidants; Disease Models, Animal; Inflammation; Ischemia; Lung; Lung Transplantation; Organ Preservation; Reperfusion Injury; Swine; Temperature | 2008 |
Genetic and pharmacologic evidence links oxidative stress to ventilator-induced lung injury in mice.
Topics: Acetylcysteine; Animals; Antioxidants; Capillary Permeability; Cytokines; Disease Models, Animal; Free Radical Scavengers; Inflammation; Male; Mice; Mice, Knockout; NF-E2-Related Factor 2; Oxidative Stress; Respiratory Distress Syndrome; Ventilators, Mechanical | 2007 |
Activation of 5-lipoxygenase and NF-kappa B in the action of acenaphthenequinone by modulation of oxidative stress.
Topics: Acenaphthenes; Acetylcysteine; Antioxidants; Arachidonate 15-Lipoxygenase; Benzoquinones; Biotransformation; Blotting, Western; Cell Line, Tumor; Enzyme Activation; Genes, Reporter; Humans; Immunoenzyme Techniques; Indicators and Reagents; Inflammation; Leukotriene B4; Luciferases; NF-kappa B; Oxidative Stress; Up-Regulation | 2008 |
Proinflammatory effects of advanced lipoxidation end products in monocytes.
Topics: Acetylcysteine; Animals; Cell Line; Cyclooxygenase 2; Gene Expression Regulation, Enzymologic; Glucose; Glycation End Products, Advanced; Humans; Inflammation; Lipid Peroxidation; Lysine; Monocytes; NF-kappa B; Rats; Receptors, CCR2 | 2008 |
Influence of ferulic acid on nicotine-induced lipid peroxidation, DNA damage and inflammation in experimental rats as compared to N-acetylcysteine.
Topics: Acetylcysteine; Alkaline Phosphatase; Animals; Antioxidants; Blotting, Western; Catalase; Comet Assay; Coumaric Acids; Cyclooxygenase 2; DNA Damage; Glutathione; Glutathione Peroxidase; Inflammation; Injections, Subcutaneous; Intubation, Gastrointestinal; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Molecular Structure; NF-kappa B; Nicotine; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2008 |
S-nitroso-N-acetylcysteine (SNAC) prevents myocardial alterations in hypercholesterolemic LDL receptor knockout mice by antiinflammatory action.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Blood Pressure; CD40 Ligand; Gene Expression Regulation, Enzymologic; Hypercholesterolemia; Hypertension; Hypertrophy, Left Ventricular; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Contraction; Nitric Oxide Synthase Type III; Receptors, LDL | 2008 |
Multimodality prevention of contrast-induced acute kidney injury.
Topics: Acetylcysteine; Acute Kidney Injury; Antioxidants; Ascorbic Acid; Biomarkers; Cell Death; Cell Hypoxia; Consensus; Contrast Media; Creatinine; Epithelial Cells; Fluid Therapy; Humans; Inflammation; Infusions, Intravenous; Kidney Tubules; Multicenter Studies as Topic; Oxidative Stress; Practice Guidelines as Topic; Protective Agents; Randomized Controlled Trials as Topic; Renal Circulation; Treatment Outcome | 2008 |
Hyperbaric oxygen attenuates apoptosis and decreases inflammation in an ischemic wound model.
Topics: Acetylcysteine; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cyclooxygenase 2; Free Radical Scavengers; Hyperbaric Oxygenation; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Ischemia; Male; Membrane Proteins; Mitochondrial Proteins; Models, Animal; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Signal Transduction; Tumor Suppressor Protein p53; Vascular Endothelial Growth Factor A; Wound Healing; Wounds and Injuries | 2008 |
BV-2 stimulation by lactacystin results in a strong inflammatory reaction and apoptotic neuronal death in SH-SY5Y cells.
Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Apoptosis; Cell Line; Cell Survival; Culture Media, Conditioned; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Humans; I-kappa B Proteins; Inflammation; Macrophage Activation; Mice; Microglia; Minocycline; Neurons; NF-KappaB Inhibitor alpha; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Proteasome Endopeptidase Complex | 2008 |
N-acetylcysteine derivative inhibits CD40-dependent proinflammatory properties of human pancreatic duct cells.
Topics: Acetylcysteine; Adenocarcinoma; CD40 Antigens; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Lysine; NF-kappa B; Pancreatic Ducts; Pancreatic Neoplasms; Transcription, Genetic | 2008 |
The reduction of experimentally induced inflammation by sulfhydryl compounds.
Topics: Acetylcysteine; Animals; Dexamethasone; Drug Synergism; Hydrocortisone; Inflammation; Male; Methionine; Penicillamine; Rabbits; Salicylates | 1967 |
N-acetylcysteine delays the infiltration of inflammatory cells into the lungs of paraquat-intoxicated rats.
Topics: Acetylcysteine; Animals; Bronchoalveolar Lavage Fluid; Chemotactic Factors; Chemotaxis, Leukocyte; Inflammation; Liver; Lung Diseases; Male; Neutrophils; Paraquat; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Superoxides | 1993 |
In vivo antioxidant treatment suppresses nuclear factor-kappa B activation and neutrophilic lung inflammation.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Base Sequence; Chemokines, CXC; Chemotactic Factors; Chemotaxis, Leukocyte; Dinoprost; Disease Models, Animal; Drug Evaluation, Preclinical; Endotoxins; F2-Isoprostanes; Gene Expression Regulation; Glutathione; Growth Substances; Inflammation; Intercellular Signaling Peptides and Proteins; Leukocyte Count; Lung; Lung Diseases; Male; Molecular Sequence Data; Neutrophils; NF-kappa B; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; RNA, Messenger; Sepsis | 1996 |
N-acetylcysteine and alpha-tocopherol reverse the inflammatory response in activated rat Kupffer cells.
Topics: Acetylcysteine; Animals; Inflammation; Kupffer Cells; Macrophage Activation; Male; Rats; Rats, Sprague-Dawley; Vitamin E | 1997 |
Functional characterization of recombinant rat macrophage inflammatory protein-1 alpha and mRNA expression in pulmonary inflammation.
Topics: Acetylcysteine; Animals; Bronchoalveolar Lavage Fluid; Cell Line; Chemokine CCL4; Chemotaxis, Leukocyte; Dimethyl Sulfoxide; Gene Expression; Inflammation; Lipopolysaccharides; Lung; Lymphocyte Activation; Macrophage Inflammatory Proteins; Macrophages; Macrophages, Alveolar; Male; Neutrophils; Rats; Rats, Sprague-Dawley; Recombinant Proteins | 1998 |
Cytokine-mediated induction of ceramide production is redox-sensitive. Implications to proinflammatory cytokine-mediated apoptosis in demyelinating diseases.
Topics: Acetylcysteine; Adrenoleukodystrophy; Amitrole; Animals; Antioxidants; Apoptosis; Brain; Cells, Cultured; Ceramides; Cytokines; Diamide; DNA Fragmentation; Glutathione; Glutathione Disulfide; Hydrogen Peroxide; Inflammation; Interleukin-1; Multiple Sclerosis; Oxidation-Reduction; Pyrrolidines; Rats; Reactive Oxygen Species; Sphingomyelins; Thiocarbamates; Tumor Necrosis Factor-alpha | 1998 |
Inhibitory and stimulatory effects of lactacystin on expression of nitric oxide synthase type 2 in brain glial cells. The role of Ikappa B-beta.
Topics: Acetylcysteine; Animals; Astrocytoma; Brain; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Enzyme Induction; Gene Expression Regulation, Enzymologic; Glioma; Humans; I-kappa B Proteins; Inflammation; Interferons; Interleukin-1; Kinetics; Neuroglia; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Promoter Regions, Genetic; Rats; Recombinant Proteins; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 2000 |
IL-4-induced oxidative stress upregulates VCAM-1 gene expression in human endothelial cells.
Topics: Acetylcysteine; Arteriosclerosis; Cells, Cultured; Endothelium, Vascular; Genes, Reporter; Humans; Inflammation; Interleukin-4; Oxidative Stress; Promoter Regions, Genetic; Pyrrolidines; Reverse Transcriptase Polymerase Chain Reaction; Sp1 Transcription Factor; Thiocarbamates; Transcription Factors; Transcription, Genetic; Transfection; Umbilical Veins; Up-Regulation; Vascular Cell Adhesion Molecule-1 | 2001 |
N-acetylcysteine and endothelial cell injury by sulfur mustard.
Topics: Acetylcysteine; Animals; Apoptosis; Cattle; Cytokines; Dermatologic Agents; Endothelium; Gene Expression Regulation; Glutathione; Inflammation; Mustard Gas; NF-kappa B | 2000 |
N-acetylcysteine inhibited nuclear factor-kappaB expression and the intimal hyperplasia in rat carotid arterial injury.
Topics: Acetylcysteine; Animals; Carotid Arteries; Carotid Artery Injuries; Carotid Stenosis; Cell Division; Coronary Restenosis; Cytokines; Disease Models, Animal; Free Radical Scavengers; Hyperplasia; Immunohistochemistry; Inflammation; Male; Muscle, Smooth, Vascular; NF-kappa B; Rats; Rats, Sprague-Dawley; Tunica Intima | 2001 |
Glutathione protects mice from lethal sepsis by limiting inflammation and potentiating host defense.
Topics: Acetylcysteine; Animals; Cell Movement; Chemokines; Glutathione; Immunity, Innate; Inflammation; Male; Mice; Mice, Inbred ICR; Neutrophils; Sepsis | 2002 |
Intracellular antioxidant activity is necessary to modulate the macrophage response to endotoxin.
Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Blood Coagulation Factors; Butylated Hydroxyanisole; Cells, Cultured; Chromans; Endotoxins; F2-Isoprostanes; Inflammation; Macrophages, Alveolar; Male; Rabbits; Reactive Oxygen Species; Respiratory Distress Syndrome; Signal Transduction; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2002 |