acetylcysteine has been researched along with Injury, Myocardial Reperfusion in 68 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (1.47) | 18.7374 |
1990's | 12 (17.65) | 18.2507 |
2000's | 26 (38.24) | 29.6817 |
2010's | 27 (39.71) | 24.3611 |
2020's | 2 (2.94) | 2.80 |
Authors | Studies |
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Apaijai, N; Arunsak, B; Chattipakorn, N; Chattipakorn, SC; Chunchai, T; Liang, G; Maneechote, C; Pintana, H; Singhanat, K; Vongsfak, J; Wu, D | 1 |
Chen, R; Leng, Y; Li, W; Xia, Z; Xiong, Y; Xue, R | 1 |
Barancik, M; Bartekova, M; Dhalla, NS; Ferenczyova, K | 1 |
Bai, B; Dong, A; Jing, X; Liu, H; Wang, H | 1 |
Bahremand, M; Eshraghi, A; Jalali, A; Mortazavi, SH; Nozari, Y; Pourhosseini, H; Salamzadeh, J; Salarifar, M; Talasaz, AH | 1 |
Akbarzadeh, S; Anvaripour, A; Bahtoei, M; Iranpour, D; Movahed, A; Netticadan, T; Ostovar, A; Raj, P; Shafiei, E; Shahryari, H; Tahmasebi, R | 1 |
Correa, F; El Hafidi, M; Esparza-Perusquía, M; Flores-Herrera, O; Olvera-Sánchez, S; Ostolga-Chavarría, M; Ramírez-Camacho, I; Silva-Palacios, A; Zazueta, C | 1 |
Apaijai, N; Chattipakorn, K; Chattipakorn, N; Chattipakorn, SC; Jaiwongkum, T; Palee, S; Pratchayasakul, W; Sivasinprasasn, S | 1 |
Ibanez, B; Lobo-Gonzalez, M; Rossello, X | 1 |
Bell, SP; Chen, Z; Christian, TF; Dauerman, HL; Gibson, PC; Keating, FF; Lachapelle, RR; LeWinter, MM; Meyer, M; Nyotowidjojo, I | 1 |
Irwin, MG; Lei, S; Li, H; Liu, Z; Mao, X; Ng, KF; Qiao, S; Vanhoutte, PM; Wang, J; Wang, T; Wong, GT; Xia, Z; Xu, A | 1 |
Gao, X; Irwin, MG; Liao, XL; Liu, Y; Mao, X; Ng, KF; Ou, JS; Vanhoutte, PM; Wang, T; Xia, Z; Xu, Y | 1 |
Baotic, I; Bienengraeber, M; Bosnjak, ZJ; Kersten, JR; Lazar, J; Muravyeva, M; Sedlic, F; Warltier, DC | 1 |
Chen, Y; Gao, F; Huang, Z; Li, W; Liao, H; Lu, S; Shi, G; Sun, T; Wang, B; Xu, H; Zhang, Y; Zheng, F; Zhong, S | 1 |
Adams, B; Essop, MF; Mapanga, RF | 1 |
Irwin, MG; Li, H; Li, Y; Lin, J; Wang, M; Wang, T; Xia, Z | 1 |
Dasgupta, C; Huang, X; Li, Y; Wang, L; Xiao, D; Zhang, L | 1 |
Lei, S; Lian, Q; Liu, H; Su, W; Xia, Z; Xia, ZY; Xu, J; Zhan, L; Zhang, Q; Zhang, Y; Zhu, Q | 1 |
Abe, M; Ichimaru, S; Kaji, S; Takiguchi, Y; Tsuchiya, K; Wada, K | 1 |
Erdogan, D; Ibrisim, E; Kapan, S; Ozaydin, M; Peker, O; Peker, T; Sutcu, R | 1 |
Baldwin, AS; Moss, NC; Selzman, CH; Stansfield, WE; Tang, RH; Willis, M | 1 |
Bayar, MK; Burma, O; Halifeoğlu, I; Köksal, H; Rahman, A | 1 |
Chapman, D; Dhalla, NS; Elimban, V; Maddika, S | 1 |
DI, JF; Feng, Z; Lin, Y; Zeng, S | 1 |
Altun, G; Karahan, SC; Kopuz, M; Koramaz, I; Menteşe, A; Topbaş, M; Uçar, U | 1 |
Chen, N; Ko, M | 1 |
Adams, V; Desch, S; Diederich, KW; Eitel, I; Erbs, S; Fuernau, G; Gutberlet, M; Hildebrand, L; Linke, A; Nowak, M; Schirdewahn, C; Schuler, G; Thiele, H | 1 |
Kurian, GA; Paddikkala, J | 1 |
Abdallah, Y; Erdogan, A; Gündüz, D; Iraqi, W; Kasseckert, SA; Ladilov, Y; Neuhof, C; Piper, HM; Reusch, HP; Said, M; Schlüter, KD; Shahzad, T; Tillmanns, H | 1 |
Balková, P; Hlaváčková, M; Kolář, F; Milerová, M; Neckář, J; Novák, F; Nováková, O | 1 |
Buller, CL; Charpie, JR; Peng, YW | 1 |
Fujita, M; Iwasaka, T; Okazaki, T; Otani, H; Shimazu, T; Yoshioka, K | 1 |
Irwin, MG; Lam, KS; Lei, S; Liu, Y; Ng, KF; Qiao, S; Wang, T; Xia, Z; Xu, A | 1 |
Dixon, B; Patterson, AJ; Xiao, D; Xiong, F; Zhang, L | 1 |
Bauersachs, J; Becker, BF; Brielmeier, M; Conrad, M; David, R; Franz, WM; Hinkel, R; Horstkotte, J; Jeremias, I; Kiermayer, C; Kupatt, C; Lange, P; Mandal, PK; Naebauer, M; Perisic, T; Schmitt, S; Schneider, M; Schroeder, M; Schulz, S; Sinowatz, F; Widder, J; Ziegler, T; Zischka, H | 1 |
Adams, J; Ardeshirpour, F; Baldwin, AS; Bellinger, DA; Elliott, PJ; Fischer, TH; McCain, A; Merricks, E; Nichols, TC; Pien, C; Pye, J | 1 |
Bai, A; Calvillo, L; De Angelis, N; Fiordaliso, F; Ghezzi, P; Latini, R; Masson, S; Pollicino, L; Salio, M; Santangelo, F | 1 |
Allen, SJ; Cox, CS; Fischer, UM; Laine, GA; Mehlhorn, U; Stewart, RH | 1 |
Bloch, W; Dodos, F; Hellmich, M; Huebner, A; Kasper, SM; Klass, O; Mehlhorn, U; Raji, MR; Suedkamp, M; Tossios, P | 1 |
Angelos, MG; Klawitter, PF; Palmer, BS; Reiser, PJ | 1 |
Evora, PR; Rodrigues, AJ; Schaff, HV | 1 |
Aka, SA; Aykaç, Z; Orhan, G; Sargin, M; Senay, S; Yalçin, AS; Yapici, N; Yuksel, M | 1 |
Das, DK; Das, S; Engelman, RM; Maulik, N | 1 |
Bouchard, D; Carrier, M; Cartier, R; Demers, P; El-Hamamsy, I; Page, P; Pellerin, M; Perrault, LP; Stevens, LM | 1 |
Moss, NC; Selzman, CH; Stansfield, WE; Tang, R; Willis, MS | 1 |
Aydin, A; Bolcal, C; Demirkilic, U; Doganci, S; Kuralay, E; Oz, BS; Ozal, E; Sargin, M; Sayal, A; Tatar, H; Yildirim, V | 1 |
Cagiano, R; Cazzato, A; Colantuono, G; D'Agostino, D; Di Venosa, N; Federici, A; Fiore, T; Rastaldo, R; Tiravanti, EA | 1 |
Elmes, MJ; Gardner, DS; Langley-Evans, SC; McMullen, S | 1 |
Das, DK; Goswami, S; Gurusamy, N; Malik, G | 1 |
Kucharská, J; Matejíková, J; Pancza, D; Pintérová, M; Ravingerová, T | 1 |
Abe, M; Ichimaru, S; Takiguchi, Y; Tsuchiya, K; Wada, K | 1 |
Collis, CS; Davies, MJ; Rice-Evans, C | 1 |
De Wit, N; Gillet, R; Huyghens, L; Spapen, H; Zhang, H | 1 |
Arnet, U; Lüscher, TF; Siebenmann, R; Stulz, P; Turina, M; von Segesser, LK; Yang, Z | 1 |
Musilová, B; Rocek, M; Sochman, J; Vrbská, J | 1 |
Berti, F; Chiesara, E; Michael, M; Oriani, G; Radice, S; Rossoni, G | 1 |
Bernareggi, M; Berti, F; Chiesara, E; Oriani, G; Polvani, G; Radice, S; Rossoni, G | 1 |
Hegde, BM; Tripathi, Y | 1 |
Garcia-Dorado, D; Hofstaetter, B; Inserte, J; Piper, HM; Taimor, G | 1 |
Bishopric, NH; Discher, DJ; Hernandez, OM; Webster, KA | 1 |
Hegde, BM; Raghuveer, CV; Rai, YS; Tripathi, Y | 1 |
Dhalla, NS; Elmoselhi, AB; Hata, T; Makino, N | 1 |
Sochman, J | 1 |
Gauduel, Y; Grousset, C; Menasché, P; Mouas, C; Piwnica, A | 1 |
Bernier, M; Hearse, DJ; Qiu, Y | 1 |
Tang, LD; Tang, ZM | 1 |
Fabián, J; Kolc, J; Sochman, J; Vrána, M | 1 |
Goldfarb, RD; Singh, A | 1 |
5 review(s) available for acetylcysteine and Injury, Myocardial Reperfusion
Article | Year |
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Beneficial Effects of N-acetylcysteine and N-mercaptopropionylglycine on Ischemia Reperfusion Injury in the Heart.
Topics: Acetylcysteine; Animals; Antioxidants; Heart; Humans; Myocardial Reperfusion Injury; Oxidative Stress; Tiopronin | 2018 |
Editor's Choice- Pathophysiology and therapy of myocardial ischaemia/reperfusion syndrome.
Topics: Acetylcysteine; Acute Disease; Administration, Intravenous; Adrenergic beta-1 Receptor Antagonists; Animals; Cardiotonic Agents; Exenatide; Free Radical Scavengers; Humans; Hypoglycemic Agents; Incidence; Metoprolol; Mice; Mice, Transgenic; Microcirculation; Models, Animal; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Percutaneous Coronary Intervention; Randomized Controlled Trials as Topic; ST Elevation Myocardial Infarction | 2019 |
[Acetylcysteine: a promising antioxidant for cardiorespiratory disorders].
Topics: Acetaminophen; Acetylcysteine; Acquired Immunodeficiency Syndrome; Antioxidants; Chemical and Drug Induced Liver Injury; Humans; Myocardial Reperfusion Injury; Nitrates; Reactive Oxygen Species; Respiratory Distress Syndrome | 1994 |
Status of myocardial antioxidants in ischemia-reperfusion injury.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Catalase; Glutathione Peroxidase; Humans; Ischemic Preconditioning, Myocardial; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Superoxide Dismutase; Vitamin E | 2000 |
N-acetylcysteine in acute cardiology: 10 years later: what do we know and what would we like to know?!
Topics: Acetylcysteine; Cardiology; Clinical Trials as Topic; Free Radical Scavengers; Humans; Myocardial Infarction; Myocardial Reperfusion Injury; Oxidative Stress; Reactive Oxygen Species; Ventricular Function, Left | 2002 |
11 trial(s) available for acetylcysteine and Injury, Myocardial Reperfusion
Article | Year |
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Protection from Reperfusion Injury with Intracoronary N-Acetylcysteine in Patients with STEMI Undergoing Primary Percutaneous Coronary Intervention in a Cardiac Tertiary Center.
Topics: Acetylcysteine; Aged; Cardiotonic Agents; Double-Blind Method; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Injections, Intra-Arterial; Iran; Male; Middle Aged; Myocardial Reperfusion Injury; Percutaneous Coronary Intervention; Prospective Studies; ST Elevation Myocardial Infarction; Tertiary Care Centers | 2018 |
Effects of N-acetyl cysteine and melatonin on early reperfusion injury in patients undergoing coronary artery bypass grafting: A randomized, open-labeled, placebo-controlled trial.
Topics: Acetylcysteine; Adult; Aged; Antioxidants; Cardiotonic Agents; Coronary Artery Bypass; Coronary Disease; Drug Monitoring; Female; Humans; Male; Melatonin; Middle Aged; Myocardial Reperfusion Injury; Oxidative Stress; Treatment Outcome | 2018 |
Effects of intravenous N-acetylcysteine on periprocedural myocardial injury after on-pump coronary artery by-pass grafting.
Topics: Acetylcysteine; Adult; Aged; Antioxidants; Biomarkers; Coronary Artery Bypass; Creatine Kinase, MB Form; Double-Blind Method; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Myocardial Reperfusion Injury; Myocardium; Prospective Studies; Time Factors; Treatment Failure; Troponin T | 2008 |
The effects of low dose N-acetylcysteine (NAC) as an adjunct to cardioplegia in coronary artery bypass surgery.
Topics: Acetylcysteine; Aged; Cardiopulmonary Bypass; Coronary Artery Bypass; Coronary Artery Disease; Creatine Kinase, MB Form; Female; Free Radical Scavengers; Heart Arrest, Induced; Humans; Inflammation Mediators; Male; Middle Aged; Myocardial Reperfusion Injury; Oxidative Stress; Prospective Studies; Reactive Oxygen Species; Treatment Outcome | 2008 |
Ischemia-modified albumin reduction after coronary bypass surgery is associated with the cardioprotective efficacy of cold-blood cardioplegia enriched with N-acetylcysteine: a preliminary study.
Topics: Acetylcysteine; Albumins; Cardiotonic Agents; Cold Temperature; Coronary Artery Bypass; Female; Heart Arrest, Induced; Humans; Male; Malondialdehyde; Middle Aged; Myocardial Reperfusion Injury; Troponin T | 2010 |
Impact of high-dose N-acetylcysteine versus placebo on contrast-induced nephropathy and myocardial reperfusion injury in unselected patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. The LIPSIA-
Topics: Acetylcysteine; Acute Kidney Injury; Aged; Angioplasty, Balloon, Coronary; Contrast Media; Creatinine; Female; Free Radical Scavengers; Humans; Logistic Models; Magnetic Resonance Imaging; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion Injury; Oxidative Stress; Prospective Studies; Single-Blind Method; Treatment Outcome | 2010 |
N-acetylcysteine and magnesium improve biochemical abnormalities associated with myocardial ischaemic reperfusion in South Indian patients undergoing coronary artery bypass grafting: a comparative analysis.
Topics: Acetylcysteine; Adenosine Triphosphatases; Analysis of Variance; Biomarkers; Coronary Artery Bypass; Erythrocytes; Female; Free Radical Scavengers; Free Radicals; Humans; India; Lipid Peroxidation; Magnesium Compounds; Male; Middle Aged; Myocardial Reperfusion Injury; Oxidative Stress; Postoperative Complications; Thiobarbituric Acid Reactive Substances | 2010 |
N-acetylcysteine prevents reactive oxygen species-mediated myocardial stress in patients undergoing cardiac surgery: results of a randomized, double-blind, placebo-controlled clinical trial.
Topics: Acetylcysteine; Aged; Biopsy, Needle; Cardiopulmonary Bypass; Confidence Intervals; Coronary Artery Bypass; Coronary Stenosis; Double-Blind Method; Female; Follow-Up Studies; Heart Function Tests; Hemodynamics; Humans; Immunohistochemistry; Infusions, Intravenous; Intraoperative Period; Male; Middle Aged; Myocardial Reperfusion Injury; Probability; Reactive Oxygen Species; Reference Values; Stress, Physiological; Treatment Outcome | 2003 |
Effects of N-acetylcysteine on myocardial ischemia-reperfusion injury in bypass surgery.
Topics: Acetylcysteine; Acridines; Aged; Biomarkers; Cardiopulmonary Bypass; Coronary Artery Bypass; Coronary Artery Disease; Creatine Kinase, MB Form; Female; Follow-Up Studies; Free Radical Scavengers; Humans; Indicators and Reagents; Inflammation Mediators; Luminescent Measurements; Luminol; Male; Middle Aged; Myocardial Reperfusion Injury; Oxidative Stress; Reactive Oxygen Species; Research Design; Treatment Outcome; Tumor Necrosis Factor-alpha | 2006 |
Effect of intravenous N-acetylcysteine on outcomes after coronary artery bypass surgery: a randomized, double-blind, placebo-controlled clinical trial.
Topics: Acetylcysteine; Administration, Oral; Adult; Aged; Anti-Inflammatory Agents; Antioxidants; Cardiopulmonary Bypass; Coronary Artery Bypass; Double-Blind Method; Female; Humans; Injections, Intravenous; Interleukin-6; Male; Middle Aged; Myocardial Reperfusion Injury; Postoperative Complications; Preoperative Care | 2007 |
Infarct Size Limitation: acute N-acetylcysteine defense (ISLAND trial): preliminary analysis and report after the first 30 patients.
Topics: Acetylcysteine; Aged; Creatine Kinase; Drug Therapy, Combination; Electrocardiography; Fibrinolytic Agents; Free Radical Scavengers; Humans; Middle Aged; Myocardial Infarction; Myocardial Reperfusion Injury; Pilot Projects; Streptokinase; Stroke Volume; Thrombolytic Therapy; Ventricular Function, Left | 1996 |
52 other study(ies) available for acetylcysteine and Injury, Myocardial Reperfusion
Article | Year |
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Acute administration of myeloid differentiation factor 2 inhibitor and N-acetyl cysteine attenuate brain damage in rats with cardiac ischemia/reperfusion injury.
Topics: Acetylcysteine; Animals; Brain; Encephalitis; Ischemia; Male; Myocardial Reperfusion Injury; Oxidative Stress; Rats; Reperfusion Injury | 2023 |
Mechanism of N-acetylcysteine in alleviating diabetic myocardial ischemia reperfusion injury by regulating PTEN/Akt pathway through promoting DJ-1.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Cell Line; Diabetic Cardiomyopathies; Disease Models, Animal; Male; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Stress; Protein Deglycase DJ-1; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Rats; Rats, Sprague-Dawley; Signal Transduction | 2020 |
Overexpression of TIMP3 Protects Against Cardiac Ischemia/Reperfusion Injury by Inhibiting Myocardial Apoptosis Through ROS/Mapks Pathway.
Topics: Acetylcysteine; Animals; Anthracenes; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cells, Cultured; Cyclic N-Oxides; Doxorubicin; Echocardiography; Heart; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Spin Labels; Tissue Inhibitor of Metalloproteinase-3 | 2017 |
Cardioprotective strategies preserve the stability of respiratory chain supercomplexes and reduce oxidative stress in reperfused ischemic hearts.
Topics: Acetylcysteine; Animals; Antioxidants; Cardiotonic Agents; Electron Transport; Electron Transport Complex I; Electron Transport Complex III; Electron Transport Complex IV; Gene Expression Regulation; Ischemic Postconditioning; Mitochondria, Heart; Mitochondrial Membranes; Myocardial Reperfusion Injury; Myocardium; Oxidative Phosphorylation; Oxidative Stress; Oxygen Consumption; Rats; Rats, Wistar | 2018 |
N-acetylcysteine with low-dose estrogen reduces cardiac ischemia-reperfusion injury.
Topics: Acetylcysteine; Animals; Cardiotonic Agents; Dose-Response Relationship, Drug; Estradiol; Estrogens; Female; Heart Rate; Humans; Mitochondria, Heart; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Ovariectomy; Rats, Wistar | 2019 |
High dose intracoronary N-acetylcysteine in a porcine model of ST-elevation myocardial infarction.
Topics: Acetylcysteine; Animals; Contrast Media; Coronary Angiography; Disease Models, Animal; Female; Free Radical Scavengers; Iopamidol; Myocardial Infarction; Myocardial Reperfusion Injury; Swine | 2013 |
N-Acetylcysteine and allopurinol up-regulated the Jak/STAT3 and PI3K/Akt pathways via adiponectin and attenuated myocardial postischemic injury in diabetes.
Topics: Acetylcysteine; Adiponectin; Allopurinol; Animals; Diabetes Complications; Diabetes Mellitus, Experimental; Gene Expression Regulation; Humans; Janus Kinases; Male; Myocardial Reperfusion Injury; Myocytes, Cardiac; Nitric Oxide; Phosphatidylinositol 3-Kinases; Phosphorylation; Rats; Signal Transduction; STAT3 Transcription Factor; Up-Regulation | 2013 |
N-acetylcysteine and allopurinol confer synergy in attenuating myocardial ischemia injury via restoring HIF-1α/HO-1 signaling in diabetic rats.
Topics: 2-Methoxyestradiol; Acetylcysteine; Allopurinol; Animals; Antioxidants; Apoptosis; Cardiotonic Agents; Diabetes Mellitus, Experimental; Dinoprost; Drug Synergism; Echocardiography; Estradiol; Heme Oxygenase (Decyclizing); Hypoxia-Inducible Factor 1, alpha Subunit; In Situ Nick-End Labeling; Isoprostanes; Male; Membrane Potential, Mitochondrial; Metalloporphyrins; Myocardial Reperfusion Injury; Protoporphyrins; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Signal Transduction; Superoxide Dismutase | 2013 |
Cardioprotection during diabetes: the role of mitochondrial DNA.
Topics: Acetylcysteine; Anesthetics, Inhalation; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; DNA, Mitochondrial; Free Radical Scavengers; Ischemic Preconditioning, Myocardial; Isoflurane; Male; Mitochondria, Heart; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Wistar; Reactive Oxygen Species | 2014 |
Effect of N-n-butyl haloperidol iodide on ROS/JNK/Egr-1 signaling in H9c2 cells after hypoxia/reoxygenation.
Topics: Acetylcysteine; Antipyrine; Cell Hypoxia; Cell Line; Early Growth Response Protein 1; Edaravone; Gene Expression Regulation; Haloperidol; Humans; MAP Kinase Kinase 4; MAP Kinase Signaling System; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Stress; Reactive Oxygen Species; Xanthine Oxidase | 2015 |
Partial inhibition of the ubiquitin-proteasome system ameliorates cardiac dysfunction following ischemia-reperfusion in the presence of high glucose.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Antioxidants; Autophagy; Diabetic Cardiomyopathies; Hyperglycemia; Inflammation Mediators; Isolated Heart Preparation; Leupeptins; Male; Myocardial Reperfusion Injury; Myocardium; Proteasome Inhibitors; Rats, Wistar; Superoxide Dismutase; Superoxide Dismutase-1; Time Factors | 2015 |
N-Acetylcysteine Restores Sevoflurane Postconditioning Cardioprotection against Myocardial Ischemia-Reperfusion Injury in Diabetic Rats.
Topics: Acetylcysteine; Adiponectin; Animals; Antioxidants; CD36 Antigens; Creatine Kinase, MB Form; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Forkhead Transcription Factors; Male; Methyl Ethers; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nerve Tissue Proteins; Oxidative Stress; Phosphorylation; Rats, Sprague-Dawley; Sevoflurane; STAT3 Transcription Factor; Time Factors; Troponin I | 2016 |
Protective Effect of Antenatal Antioxidant on Nicotine-Induced Heart Ischemia-Sensitive Phenotype in Rat Offspring.
Topics: Acetylcysteine; Animals; Antioxidants; Coronary Circulation; Disease Susceptibility; Drug Evaluation, Preclinical; Female; Fetus; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Infusion Pumps, Implantable; Male; Models, Biological; Myocardial Ischemia; Myocardial Reperfusion Injury; Nicotine; Oxidative Stress; Phenotype; Phosphorylation; Pregnancy; Prenatal Exposure Delayed Effects; Protein Kinase C-epsilon; Protein Processing, Post-Translational; Random Allocation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Recovery of Function; Ventricular Dysfunction, Left | 2016 |
N-acetylcysteine attenuates myocardial dysfunction and postischemic injury by restoring caveolin-3/eNOS signaling in diabetic rats.
Topics: Acetylcysteine; Animals; Antioxidants; Cardiomegaly; Caveolae; Caveolin 3; Cell Hypoxia; Cell Line; Cytoprotection; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Heart Rate; Male; Myocardial Reperfusion Injury; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Rats, Sprague-Dawley; RNA Interference; Signal Transduction; Streptozocin; Transfection; Ventricular Function, Left | 2016 |
Different effect of acute treatment with rosiglitazone on rat myocardial ischemia/reperfusion injury by administration method.
Topics: Acetylcysteine; Animals; Antioxidants; Computer Simulation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; I-kappa B Proteins; Infusions, Intravenous; Injections, Intravenous; Male; Models, Biological; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NF-kappa B; Peroxidase; Phosphorylation; PPAR gamma; Protective Agents; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Tumor Necrosis Factor-alpha | 2008 |
Inhibitory kappa B kinase-beta is a target for specific nuclear factor kappa B-mediated delayed cardioprotection.
Topics: Acetylcysteine; Animals; Creatine Kinase, MB Form; Enzyme-Linked Immunosorbent Assay; Heart Ventricles; I-kappa B Kinase; Interleukin-6; Mice; Mice, Inbred C57BL; Myocardial Reperfusion Injury; NF-kappa B; Proteins; Time Factors; Tumor Necrosis Factor-alpha | 2008 |
Role of oxidative stress in ischemia-reperfusion-induced alterations in myofibrillar ATPase activities and gene expression in the heart.
Topics: Acetylcysteine; Animals; Antioxidants; Calcium-Transporting ATPases; Cardiac Myosins; Catalase; Enzyme Inhibitors; Gene Expression Regulation; In Vitro Techniques; Leupeptins; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Myofibrils; Myosin Heavy Chains; Myosin Light Chains; Oxidative Stress; Perfusion; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase; Ventricular Dysfunction, Left; Ventricular Pressure; Xanthine; Xanthine Oxidase | 2009 |
[Protective effects and mechanism of N-acetylcysteine on cardiac injury induced by ischemia/reperfusion in diabetic rats].
Topics: Acetylcysteine; Animals; Diabetes Complications; Disease Models, Animal; Female; Humans; Ischemia; Male; Myocardial Reperfusion Injury; Myocytes, Cardiac; Random Allocation; Rats; Rats, Sprague-Dawley | 2009 |
Schisandrin B-induced glutathione antioxidant response and cardioprotection are mediated by reactive oxidant species production in rat hearts.
Topics: Acetylcysteine; alpha-Tocopherol; Animals; Antioxidants; Cardiovascular Agents; Cyclooctanes; Cytochrome P-450 Enzyme System; Drugs, Chinese Herbal; Female; Glutathione; Lignans; Microsomes; Mitochondria; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; NADP; Oxidation-Reduction; Phytotherapy; Polycyclic Compounds; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Schisandra | 2010 |
Interplay between Ca2+ cycling and mitochondrial permeability transition pores promotes reperfusion-induced injury of cardiac myocytes.
Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Calcium; Cyclosporine; Fluoresceins; Male; Membrane Potential, Mitochondrial; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Reperfusion Injury; Myocytes, Cardiac; Necrosis; Rats; Rats, Wistar; Reactive Oxygen Species; Ruthenium Compounds; Ryanodine; Thapsigargin; Tiopronin | 2011 |
N-acetylcysteine treatment prevents the up-regulation of MnSOD in chronically hypoxic rat hearts.
Topics: Acetylcysteine; Animals; Free Radical Scavengers; Hypoxia; Male; Mitochondria; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Up-Regulation | 2011 |
Impact of N-acetylcysteine on neonatal cardiomyocyte ischemia-reperfusion injury.
Topics: Acetylcysteine; Analysis of Variance; Animals; Animals, Newborn; Antioxidants; Apoptosis; Caspase 3; Cell Line; Dose-Response Relationship, Drug; Glutathione; Membrane Glycoproteins; Myocardial Reperfusion Injury; Myocytes, Cardiac; NADPH Oxidase 2; NADPH Oxidases; Oxidation-Reduction; Oxidative Stress; Perfusion; Rabbits; Rats; Reactive Oxygen Species; Time Factors | 2011 |
Ascorbic acid and N-acetyl cysteine prevent uncoupling of nitric oxide synthase and increase tolerance to ischemia/reperfusion injury in diabetic rat heart.
Topics: Acetylcysteine; Animals; Ascorbic Acid; Biopterins; Diabetes Mellitus, Experimental; Disease Models, Animal; Male; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2011 |
N-acetylcysteine and allopurinol synergistically enhance cardiac adiponectin content and reduce myocardial reperfusion injury in diabetic rats.
Topics: Acetylcysteine; Adiponectin; Allopurinol; Animals; Antioxidants; Biomarkers; Blood Glucose; Creatine Kinase, MB Form; Diabetes Complications; Dinoprost; Drug Synergism; Gene Expression Regulation; Hemodynamics; Interleukin-6; Isoprostanes; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, Adiponectin; Signal Transduction; Tumor Necrosis Factor-alpha | 2011 |
Hypoxia-derived oxidative stress mediates epigenetic repression of PKCε gene in foetal rat hearts.
Topics: Acetylcysteine; Animals; Cyclic N-Oxides; DNA Methylation; Epigenesis, Genetic; Female; Fetal Heart; Gene Expression Regulation, Developmental; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Myocardial Reperfusion Injury; NADPH Oxidases; Oxidative Stress; Pregnancy; Promoter Regions, Genetic; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spin Labels | 2012 |
Mitochondrial thioredoxin reductase is essential for early postischemic myocardial protection.
Topics: Acetylcysteine; Animals; Cell Death; Cells, Cultured; Cyclosporine; Embryonic Stem Cells; Endothelial Cells; Enzyme Inhibitors; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Hematopoietic Stem Cells; Mice; Mice, Knockout; Mitochondria; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Stress; Sulfhydryl Compounds; Thioredoxin Reductase 1; Thioredoxin Reductase 2 | 2011 |
Proteasome inhibition ablates activation of NF-kappa B in myocardial reperfusion and reduces reperfusion injury.
Topics: Acetylcysteine; Animals; Creatine Kinase; Creatine Kinase, MB Form; Cysteine Endopeptidases; Disease Models, Animal; Enzyme Inhibitors; Female; Isoenzymes; Male; Multienzyme Complexes; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; NF-kappa B; Proteasome Endopeptidase Complex; Swine; Troponin I | 2003 |
In vivo cardioprotection by N-acetylcysteine and isosorbide 5-mononitrate in a rat model of ischemia-reperfusion.
Topics: Acetylcysteine; Animals; Blood Pressure; Drug Therapy, Combination; Free Radical Scavengers; Isosorbide Dinitrate; Male; Monocytes; Myocardial Infarction; Myocardial Reperfusion Injury; Neutrophils; Nitric Oxide Donors; Rats; Rats, Sprague-Dawley | 2003 |
The antioxidant N-acetylcysteine preserves myocardial function and diminishes oxidative stress after cardioplegic arrest.
Topics: Acetylcysteine; Animals; Antioxidants; Cardiopulmonary Bypass; Disease Models, Animal; Dogs; Female; Heart Arrest, Induced; Heart Function Tests; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Oxidative Stress; Probability; Random Allocation; Reference Values; Risk Assessment; Sensitivity and Specificity; Ventricular Function, Left | 2003 |
Degradation of rat cardiac troponin I during ischemia independent of reperfusion.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; Animals; Antioxidants; Blotting, Western; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Sprague-Dawley; Time Factors; Troponin I | 2004 |
Protective effect of N-acetylcysteine against oxygen radical-mediated coronary artery injury.
Topics: Acetylcysteine; Animals; Coronary Vessels; Dogs; Endothelium, Vascular; Female; Male; Myocardial Reperfusion Injury; Oxidative Stress; Reactive Oxygen Species; Vasoconstriction; Vasodilation | 2004 |
Angiotensin preconditioning of the heart: evidence for redox signaling.
Topics: Acetophenones; Acetylcysteine; Angiotensin II; Animals; Antioxidants; Apoptosis; Gene Expression; Heart; Heart Rate; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Male; Membrane Glycoproteins; Membrane Transport Proteins; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; NADPH Oxidase 2; NADPH Oxidases; Oxidation-Reduction; Perfusion; Phosphoproteins; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Ventricular Function, Left; Ventricular Remodeling | 2006 |
Proteasome inhibition attenuates infarct size and preserves cardiac function in a murine model of myocardial ischemia-reperfusion injury.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardial Reperfusion Injury; NF-kappa B; Proteasome Inhibitors | 2007 |
Do N-acetylcystein, beta-glucan, and coenzyme Q10 mollify myocardial ischemia-reperfusion injury?
Topics: Acetylcysteine; Animals; Antioxidants; beta-Glucans; Coenzymes; Disease Models, Animal; Female; Myocardial Reperfusion Injury; Rabbits; Ubiquinone | 2007 |
Hyperoxia confers myocardial protection in mechanically ventilated rats through the generation of free radicals and opening of mitochondrial ATP-sensitive potassium channels.
Topics: Acetylcysteine; Animals; Blood Pressure; Coronary Circulation; Decanoic Acids; Disease Models, Animal; Free Radical Scavengers; Glyburide; Heart Rate; Hydroxy Acids; Hypoxia; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Reactive Oxygen Species; Respiration, Artificial; Time Factors; Ventricular Function, Left; Ventricular Pressure | 2008 |
Prenatal diet determines susceptibility to cardiac ischaemia-reperfusion injury following treatment with diethylmaleic acid and N-acetylcysteine.
Topics: Acetylcysteine; Animals; Diet, Protein-Restricted; Disease Models, Animal; Female; Glutathione; Heart; Hemodynamics; Maleates; Maternal Exposure; Myocardial Reperfusion Injury; Myocardium; Pregnancy; Prenatal Exposure Delayed Effects; Prenatal Nutritional Physiological Phenomena; Rats; Ventricular Dysfunction, Left | 2008 |
Oxidative injury induces selective rather than global inhibition of proteasomal activity.
Topics: Acetylcysteine; Animals; Cell Line; Cell Nucleus; Endoplasmic Reticulum; I-kappa B Proteins; Intracellular Signaling Peptides and Proteins; Ischemic Preconditioning, Myocardial; Kelch-Like ECH-Associated Protein 1; Male; Myocardial Reperfusion Injury; Myocardium; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Phosphorylation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Processing, Post-Translational; Protein Transport; Proteins; Rats; Rats, Sprague-Dawley | 2008 |
Protection against ischemia-induced ventricular arrhythmias and myocardial dysfunction conferred by preconditioning in the rat heart: involvement of mitochondrial K(ATP) channels and reactive oxygen species.
Topics: Acetylcysteine; Animals; Anti-Arrhythmia Agents; Antioxidants; Decanoic Acids; Diazoxide; Hydroxy Acids; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Lipid Peroxidation; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Perfusion; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Reactive Oxygen Species; Recovery of Function; Thiobarbituric Acid Reactive Substances; Time Factors; Ventricular Function, Left; Ventricular Premature Complexes | 2009 |
Comparison of the protective effect of N-acetylcysteine by different treatments on rat myocardial ischemia-reperfusion injury.
Topics: Acetylcysteine; Animals; Antioxidants; Disease Models, Animal; Glutathione; Glutathione Peroxidase; I-kappa B Proteins; Infusions, Intravenous; Injections, Intravenous; L-Lactate Dehydrogenase; Male; Myocardial Reperfusion Injury; Myocardium; Peroxidase; Phosphorylation; Rats; Rats, Wistar | 2008 |
Comparison of N-methyl hexanoylhydroxamic acid, a novel antioxidant, with desferrioxamine and N-acetyl cysteine against reperfusion-induced dysfunctions in isolated rat heart.
Topics: Acetylcysteine; Animals; Antioxidants; Cardiovascular Agents; Deferoxamine; Heart; Heart Rate; Hydroxamic Acids; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Perfusion; Rats; Rats, Wistar; Ventricular Function, Left; Ventricular Pressure | 1993 |
Development of nitrate tolerance in human arteries and veins: comparison of nitroglycerin and SPM 5185.
Topics: Acetylcysteine; Arginine; Dipeptides; Drug Tolerance; Free Radical Scavengers; Humans; In Vitro Techniques; Isometric Contraction; Mammary Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroglycerin; Saphenous Vein; Vasodilator Agents | 1995 |
Hyperbaric oxygen worsens myocardial low flow ischemia-reperfusion injury in isolated rat heart.
Topics: Acetylcysteine; Angiotensin II; Animals; Coronary Circulation; Free Radical Scavengers; Heart; Hyperbaric Oxygenation; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Polydeoxyribonucleotides; Rats; Rats, Sprague-Dawley; Time Factors; Vasoconstrictor Agents; Ventricular Pressure | 1997 |
Influence of acetylcysteine on aggravation of ischemic damage in ex vivo hearts of rats exposed to hyperbaric oxygen.
Topics: Acetylcysteine; Animals; Aorta, Thoracic; Coronary Circulation; Dinoprost; Endothelin-1; Free Radical Scavengers; Hyperbaric Oxygenation; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Sprague-Dawley; Ventricular Pressure | 1997 |
Effect of N-acetylcysteine on myocardial infarct size following ischemia and reperfusion in dogs.
Topics: Acetylcysteine; Animals; Blood Pressure; Coronary Vessels; Dogs; Free Radical Scavengers; Glutathione; Lipid Peroxidation; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Superoxide Dismutase | 1998 |
Influence of simulated ischemia on apoptosis induction by oxidative stress in adult cardiomyocytes of rats.
Topics: Acetylcysteine; Animals; Apoptosis; Cells, Cultured; Free Radical Scavengers; Hydrogen Peroxide; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Oxidants; Oxidative Stress; Phosphocreatine; Rats; Rats, Wistar | 2000 |
Rapid activation of neutral sphingomyelinase by hypoxia-reoxygenation of cardiac myocytes.
Topics: Acetylcysteine; Animals; Cell Hypoxia; Cells, Cultured; Ceramides; Enzyme Activation; Fibroblasts; Free Radical Scavengers; Hydrogen Peroxide; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Kinetics; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Muscle Fibers, Skeletal; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Oxidants; Oxidative Stress; Oxygen; Rats; Sphingomyelin Phosphodiesterase | 2000 |
Effect of N-acetylcysteine and sodium nitrite on myocardial reperfusion injury.
Topics: Acetylcysteine; Animals; Blood Pressure; Dogs; Drug Synergism; Free Radicals; Male; Myocardial Reperfusion Injury; Necrosis; Sodium Nitrite | 1999 |
Maintenance of the myocardial thiol pool by N-acetylcysteine. An effective means of improving cardioplegic protection.
Topics: Acetylcysteine; Animals; Cardioplegic Solutions; Free Radicals; Glutathione; Myocardial Reperfusion Injury; Myocardium; Organ Preservation; Potassium; Potassium Compounds; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Time Factors; Ventricular Function, Left | 1992 |
The influence of N-acetylcysteine on cardiac function and rhythm disorders during ischemia and reperfusion.
Topics: Acetylcysteine; Animals; Cardiac Complexes, Premature; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Rats; Rats, Inbred Strains; Tachycardia; Ventricular Fibrillation | 1990 |
[Protective effects of SH-compounds on ischemia reperfusion induced arrhythmias in the isolated rat heart].
Topics: Acetylcysteine; Animals; Arrhythmias, Cardiac; Coronary Circulation; Cysteamine; Cysteine; Dihydropyridines; Dimaprit; Female; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Rats; Rats, Inbred Strains; Thiourea | 1991 |
Cardioprotective effects of N-acetylcysteine: the reduction in the extent of infarction and occurrence of reperfusion arrhythmias in the dog.
Topics: Acetylcysteine; Animals; Arrhythmias, Cardiac; Dogs; Electrocardiography; Female; Male; Myocardial Infarction; Myocardial Reperfusion; Myocardial Reperfusion Injury; Time Factors | 1990 |
GSH and reperfusion injury.
Topics: Acetylcysteine; Glutathione; Humans; Myocardial Reperfusion Injury; Myocardium | 1989 |