acetylcysteine and Injuries, Spinal Cord

acetylcysteine has been researched along with Injuries, Spinal Cord in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.88)18.2507
2000's3 (17.65)29.6817
2010's10 (58.82)24.3611
2020's3 (17.65)2.80

Authors

AuthorsStudies
Wang, Z; Zhao, X1
Chang, G; Chen, J; Guo, X; He, J; Niu, Y; Niu, Z; Song, J; Wang, J; Wang, T; Wang, Z; Zhang, R1
Du, HY; Du, LJ; Gao, F; Jing, YL; Li, JJ; Li, ZH; Liang, YX; Liu, WB; Talifu, Z; Xu, X; Xu, XL; Yang, DG; Yu, Y; Zhang, CJ; Zhang, JM1
Lewin-Kowalik, J; Marcol, W; Olakowska, E; Woszczycka-Korczyńska, I; Właszczuk, A1
Cooper, B; Jannasch, A; Park, J; Shi, R; Tully, M; Walls, M; Zheng, L1
Barnett, SC; Boomkamp, SD; Houslay, MD; McGrath, MA1
Karalija, A; Kingham, PJ; Novikov, LN; Novikova, LN; Wiberg, M2
Eldahan, KC; Goldstein, GA; Magnuson, DS; Morehouse, J; Pandya, JD; Patel, SP; Rabchevsky, AG; Sullivan, PG; VanRooyen, JL; Yonutas, HM1
Chen, Z; Guo, J; Han, M; He, Z; Hu, J; Li, Y; Xu, Y; Zhang, B1
Acosta, G; Cao, P; Chen, Z; Muratori, B; Park, J; Shi, R; Vega-Alvarez, S; Zheng, L1
Bentley, RT; Packer, RA; Sangster, AM; Shi, R; Zheng, L1
Baltzer, WI; Hosgood, GL; Kerwin, SC; Levine, JM; McMichael, MA; Ruaux, CG; Steiner, JM1
Başkesen, A; Hanci, V; Kerimoğlu, A; Kiliç, K; Koca, K; Taştekin, D1
Khan, M; Pannu, R; Singh, AK; Singh, I; Won, JS1
Belce, A; Ciplak, N; Erdinçler, P; Gümüstas, K; Kaynar, MY; Tadayyon, E1
Aguilera, EJ; Slonimski, M1

Trials

1 trial(s) available for acetylcysteine and Injuries, Spinal Cord

ArticleYear
N-acetylcysteine amide preserves mitochondrial bioenergetics and improves functional recovery following spinal trauma.
    Experimental neurology, 2014, Volume: 257

    Topics: Acetylcysteine; Animals; Disease Models, Animal; Double-Blind Method; Drug Delivery Systems; Electron Transport Chain Complex Proteins; Energy Metabolism; Female; Ganglia, Spinal; Lameness, Animal; Mitochondria; Motor Activity; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord; Spinal Cord Injuries; Synapses; Time Factors

2014

Other Studies

16 other study(ies) available for acetylcysteine and Injuries, Spinal Cord

ArticleYear
Synergistic neuroprotective effects of hyperbaric oxygen and N-acetylcysteine against traumatic spinal cord injury in rat.
    Journal of chemical neuroanatomy, 2021, Volume: 118

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Cell Count; Combined Modality Therapy; Cytokines; Electromyography; Female; Hyperbaric Oxygenation; Neuroglia; Neuroprotective Agents; Rats; Rats, Wistar; Spinal Cord; Spinal Cord Injuries

2021
N-Acetylcysteine alleviates spinal cord injury in rats after early decompression surgery by regulating inflammation and apoptosis.
    Neurological research, 2022, Volume: 44, Issue:7

    Topics: Acetylcysteine; Animals; Apoptosis; Decompression; Inflammation; Rats; Recovery of Function; Spinal Cord; Spinal Cord Injuries

2022
Glycine and N-Acetylcysteine (GlyNAC) Combined with Body Weight Support Treadmill Training Improved Spinal Cord and Skeletal Muscle Structure and Function in Rats with Spinal Cord Injury.
    Nutrients, 2023, Oct-28, Volume: 15, Issue:21

    Topics: Acetylcholinesterase; Acetylcysteine; Animals; Body Weight; Humans; Muscle, Skeletal; Muscular Atrophy; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord Injuries

2023
The neuroprotective effect of N-acetylcysteine in spinal cord-injured rats.
    Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 2017, Volume: 26, Issue:9

    Topics: Acetylcysteine; Animals; Male; Nerve Regeneration; Neuroprotective Agents; Rats; Rats, Wistar; Spinal Cord Injuries

2017
Determination of urine 3-HPMA, a stable acrolein metabolite in a rat model of spinal cord injury.
    Journal of neurotrauma, 2013, Aug-01, Volume: 30, Issue:15

    Topics: Acetylcysteine; Acrolein; Animals; Biomarkers; Chromatography, Liquid; Disease Models, Animal; Immunoblotting; Male; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Tandem Mass Spectrometry

2013
Epac and the high affinity rolipram binding conformer of PDE4 modulate neurite outgrowth and myelination using an in vitro spinal cord injury model.
    British journal of pharmacology, 2014, Volume: 171, Issue:9

    Topics: Acetylcysteine; Animals; Animals, Newborn; Cells, Cultured; Dose-Response Relationship, Drug; Erythromycin; Nerve Fibers, Myelinated; Neurites; Phosphodiesterase 4 Inhibitors; Protein Binding; Rats; Rats, Sprague-Dawley; Rolipram; Spinal Cord Injuries

2014
The effects of N-acetyl-cysteine and acetyl-L-carnitine on neural survival, neuroinflammation and regeneration following spinal cord injury.
    Neuroscience, 2014, Jun-06, Volume: 269

    Topics: Acetylcarnitine; Acetylcysteine; Animals; Antioxidants; Apoptosis; Axons; Cell Survival; Cervical Vertebrae; Disease Models, Animal; Female; Microglia; Motor Neurons; Nerve Regeneration; Neuroimmunomodulation; Neuroprotective Agents; Random Allocation; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries

2014
N-acetylcysteine treatment following spinal cord trauma reduces neural tissue damage and improves locomotor function in mice.
    Molecular medicine reports, 2015, Volume: 12, Issue:1

    Topics: Acetylcysteine; Animals; Disease Models, Animal; Humans; Mice; Motor Activity; Neurons; Neuroprotective Agents; Oxidation-Reduction; Oxidative Stress; Recovery of Function; Spinal Cord Injuries

2015
Acrolein contributes to TRPA1 up-regulation in peripheral and central sensory hypersensitivity following spinal cord injury.
    Journal of neurochemistry, 2015, Volume: 135, Issue:5

    Topics: Acetylcysteine; Acrolein; Animals; Disease Models, Animal; Ganglia, Spinal; Hydralazine; Hyperalgesia; Locomotion; Male; Neuralgia; Pain Threshold; Rats; Rats, Sprague-Dawley; Skin; Spinal Cord; Spinal Cord Injuries; TRPA1 Cation Channel; TRPC Cation Channels; Up-Regulation; Vasodilator Agents

2015
Urinary 3-hydroxypropyl mercapturic acid (3-HPMA) concentrations in dogs with acute spinal cord injury due to intervertebral disc herniation.
    Veterinary journal (London, England : 1997), 2017, Volume: 219

    Topics: Acetylcysteine; Animals; Biomarkers; Dogs; Female; Intervertebral Disc Displacement; Male; Prospective Studies; Spinal Cord Injuries

2017
Randomized, blinded, placebo-controlled clinical trial of N-acetylcysteine in dogs with spinal cord trauma from acute intervertebral disc disease.
    Spine, 2008, Jun-01, Volume: 33, Issue:13

    Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Dinoprost; Disease Models, Animal; Dog Diseases; Dogs; Female; Infusions, Intravenous; Intervertebral Disc; Intervertebral Disc Displacement; Laminectomy; Male; Oxidative Stress; Random Allocation; Spinal Cord Injuries; Time Factors

2008
The biochemical effectiveness of N-acetylcysteine in experimental spinal cord injury in rats.
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2010, Volume: 16, Issue:1

    Topics: Acetylcysteine; Animals; Disease Models, Animal; Drug Therapy, Combination; Injections, Intraperitoneal; Injury Severity Score; Male; Malondialdehyde; Methylprednisolone; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Superoxide Dismutase

2010
Neuroprotective effects of N-acetyl-cysteine and acetyl-L-carnitine after spinal cord injury in adult rats.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Acetylcarnitine; Acetylcysteine; Animals; Antioxidants; Astrocytes; Female; Inflammation; Microglia; Microtubule-Associated Proteins; Models, Biological; Motor Neurons; Neuroglia; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries

2012
A novel role of lactosylceramide in the regulation of lipopolysaccharide/interferon-gamma-mediated inducible nitric oxide synthase gene expression: implications for neuroinflammatory diseases.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Jun-30, Volume: 24, Issue:26

    Topics: Acetylcysteine; Animals; Antigens, CD; Antioxidants; Apoptosis; Astrocytes; Cells, Cultured; Demyelinating Diseases; Drug Evaluation, Preclinical; Enzyme Induction; Enzyme Inhibitors; Fatty Acids; Female; Gait Disorders, Neurologic; Galactosyltransferases; I-kappa B Proteins; Inflammation; Interferon-gamma; Lactosylceramides; Lipopolysaccharides; Morpholines; Nerve Tissue Proteins; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidation-Reduction; Phosphorylation; Proline; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Signal Transduction; Spinal Cord Injuries; Thiocarbamates; Transfection

2004
Effect of nimodipine and N-acetylcysteine on lipid peroxidation after experimental spinal cord injury.
    Neurosurgical review, 1998, Volume: 21, Issue:4

    Topics: Acetylcysteine; Animals; Calcium Channel Blockers; Female; Free Radical Scavengers; Lipid Peroxidation; Nimodipine; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries

1998
Atelectasis and mucus plugging in spinal cord injury: case report and therapeutic approaches.
    The journal of spinal cord medicine, 2001,Winter, Volume: 24, Issue:4

    Topics: Acetylcysteine; Airway Obstruction; Bronchodilator Agents; Bronchoscopy; Combined Modality Therapy; Follow-Up Studies; Humans; Male; Middle Aged; Mucus; Pulmonary Atelectasis; Radiography; Respiratory Therapy; Spinal Cord Injuries

2001