acetylcysteine has been researched along with Hyperglycemia, Postprandial in 51 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (5.88) | 18.7374 |
| 1990's | 2 (3.92) | 18.2507 |
| 2000's | 14 (27.45) | 29.6817 |
| 2010's | 25 (49.02) | 24.3611 |
| 2020's | 7 (13.73) | 2.80 |
| Authors | Studies |
|---|---|
| Anna, Z; Izabela, S; Jan, M; Joanna, K; Mateusz, M; Małgorzata, ŻP; Paula, KS; Robert, ŁJ; Sara, Z | 1 |
| Chen, C; Chen, H; Dou, S; Li, Z; Qu, M; Wan, L; Wang, H; Wang, Q; Xie, L; Xue, J; Zhang, B; Zhang, Y; Zhou, Q | 1 |
| Almási, A; Kovács, S; Kulcsár, G; Mészáros, P; Páskuj, M | 1 |
| Chapman, C; Dludla, PV; Johnson, R; Kappo, AP; Louw, J; Mabasa, L; Mabhida, SE; Mosa, RA; Muller, CJF; Riedel, S; Sangweni, NF | 1 |
| Pal, A; Pal, S; Rao, GN | 1 |
| Acito, M; Bartolini, D; Beccari, T; Ceccarini, MR; Codini, M; Dominici, L; Galli, F; Moretti, M; Russo, C; Vannini, S; Villarini, M | 1 |
| Kossakowska, A; Kostecka-Sochoń, P; Maciejczyk, M; Matczuk, J; Zalewska, A; Żendzian-Piotrowska, M; Zięba, S | 1 |
| Chen, J; Hong, Z; Lin, Y; Ni, L; Shao, Z; Shi, Y; Sun, L; Tian, N; Wang, B; Wang, X; Wu, A; Wu, Y; Zhang, X; Zhou, Y | 1 |
| Dias, SC; Dludla, PV; Johnson, R; Nkambule, BB | 1 |
| Grider, JR; Mahavadi, S; Manion, O; Murthy, KS; Sriwai, W | 1 |
| Meshkani, R; Panahi, G; Pasalar, P; Rizzuto, R; Zare, M | 1 |
| Barbanera, PO; do Carmo, NOL; Fernandes, AAH; Kaga, AK; Queiroz, PM; Rosa, LRO | 1 |
| Du, Y; Jia, P; Jiao, S; Liu, H; Yin, H; Yuan, X; Zhang, C; Zhao, X; Zheng, J | 1 |
| Leng, B; Nie, Q; Wang, H; Zhang, L; Zhu, L | 1 |
| Chen, J; Guo, R; Huang, R; Li, S; Tian, L; Wu, K; Yan, H; You, Q | 1 |
| Okatan, EN; Toy, A; Tuncay, E; Turan, B | 1 |
| Clemens, DL; Dey, A; Kumar, SM; Swaminathan, K | 1 |
| Kumar, S; Li, X; Lockyer, P; Patterson, C; Pi, X; Portbury, AL; Xie, L | 1 |
| Fagundes, M; Fiori, CZ; Kaminski, RS; Marroni, NP; Martinez, D; Martins, EF; Montanari, CC; Rosa, DP | 1 |
| Adams, B; Essop, MF; Mapanga, RF | 1 |
| Kang, SS; Kim, JY; Park, JH; Tchah, H | 1 |
| Guo, Z; Guo, ZN; He, Y; Hu, Q; Matei, N; Tang, J; Tong, LS; Xu, L; Yang, P; Yang, Y; Zhang, JH | 1 |
| Cao, L; Chen, X; Li, W; Ma, Q; Xiao, X | 1 |
| Chu, FH; Gokila, VM; Liao, VH; Lin, CC; Mau, JL; Senthil, KK; Wang, SY; Wei, CC | 1 |
| Cheng, X; Hu, Y; Ni, B; Zhang, F; Zhao, J | 1 |
| Chiang, CK; Huang, JW; Hung, KY; Kao, SH; Liu, SY; Tsai, TJ | 1 |
| Chopra, K; Kamboj, SS; Sandhir, R | 2 |
| Kumar, S; Sitasawad, SL | 1 |
| Kamboj, SS; Sandhir, R; Vasishta, RK | 1 |
| Inadera, H; Shimomura, A; Tachibana, S; Takasaki, I; Tatematsu, M | 1 |
| Bouchier-Hayes, DJ; Lee, MJ; Moloney, MA; O'Donnell, DH | 1 |
| Bailey-Downs, L; Ballabh, P; Csiszar, A; de Cabo, R; Gautam, T; Jimenez, R; Losonczy, G; Pearson, K; Recchia, FA; Sonntag, WE; Ungvari, Z; Wilkerson, DC; Zhang, C | 1 |
| Bhat, MK; Chaube, B; Pandey, V | 1 |
| Cai, Y; Hou, W; Li, X; Shi, YY; Wang, HY; Wang, YS; Xu, CS; Yao, LB; Ye, Z; Zhang, J | 1 |
| Ji, HI; Kim, KS; Yang, HI | 1 |
| Marcheselli, F; Moroni, F; Pieri, C; Recchioni, R | 1 |
| Kehl, F; Kersten, JR; Krolikowski, JG; Pagel, PS; Warltier, DC; Weihrauch, D | 1 |
| Li, L; Renier, G; Sawamura, T | 1 |
| Barzilai, N; Berg, AH; Brownlee, M; Combs, TP; Du, X; Fantus, IG; Giacca, A; Hawkins, M; Iyengar, P; Lam, TK; Li, W; Lin, Y; Rajala, MW; Rhodes, CJ; Rollman, B; Scherer, PE | 1 |
| Gouverneur, MC; Hoekstra, JB; Holleman, F; Kastelein, JJ; Levi, M; Meijers, JC; Mooij, HL; Nieuwdorp, M; Stroes, ES; van Haeften, TW; van Lieshout, MH; Vink, H | 1 |
| Cicogna, AC; Diniz, YS; Ebaid, GM; Galhardi, CM; Novelli Filho, JL; Novelli, EL; Rocha, KK; Rodrigues, HG; Souza, GA | 1 |
| Chuang, LY; Guh, JY; Hsu, MS; Huang, JS; Huang, YJ | 1 |
| Adachi, Y; Sakurai, H; Yoshikawa, Y | 1 |
| Hsia, DY; O'Flynn, M; Rowley, WF | 1 |
| Cameron, AM; Hinson, JA; Mays, JB | 1 |
| Dunn, RJ | 1 |
| Fujitani, Y; Hori, M; Kajimoto, Y; Kaneto, H; Kawamori, R; Kishimoto, M; Matsuhisa, M; Matsuoka, T; Sakamoto, K; Watada, H; Yamasaki, Y | 1 |
| Bai, W; Guha, M; Nadler, JL; Natarajan, R | 1 |
| Deng, JF; Lin, TJ; Yang, CC | 1 |
| Boag, DE; Davidson, DF; Williamson, J | 1 |
1 trial(s) available for acetylcysteine and Hyperglycemia, Postprandial
| Article | Year |
|---|---|
Loss of endothelial glycocalyx during acute hyperglycemia coincides with endothelial dysfunction and coagulation activation in vivo.
Topics: Acetylcysteine; Adult; Blood Coagulation; Dextrans; Endothelial Cells; Glucose; Glucose Clamp Technique; Glycocalyx; Humans; Hyperglycemia; Male; Mannitol; Time Factors | 2006 |
50 other study(ies) available for acetylcysteine and Hyperglycemia, Postprandial
| Article | Year |
|---|---|
N-acetylcysteine supplementation did not reverse mitochondrial oxidative stress, apoptosis, and inflammation in the salivary glands of hyperglycemic rats.
Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Antioxidants; Apoptosis; Citrate (si)-Synthase; Diet, High-Fat; Dietary Supplements; Glutathione; Hydrogen Peroxide; Hyperglycemia; Inflammation; Male; Mitochondria; Oxidative Stress; Rats; Rats, Wistar; Salivary Glands | 2021 |
Pathogenic Role of Endoplasmic Reticulum Stress in Diabetic Corneal Endothelial Dysfunction.
Topics: Acetylcysteine; Animals; Cells, Cultured; Corneal Edema; Diabetes Mellitus, Experimental; Endoplasmic Reticulum Stress; Endothelial Cells; Humans; Hyperglycemia; Mice | 2022 |
Investigation of Intestinal Absorption and Excretion of Paracetamol in Streptozotocin-Induced Hyperglycemia.
Topics: Acetaminophen; Acetylcysteine; Animals; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Glucuronides; Glutathione; Hyperglycemia; Intestinal Absorption; Prostaglandin-Endoperoxide Synthases; Rats; Streptozocin; Sulfates | 2022 |
An In Vitro Study on the Combination Effect of Metformin and N-Acetyl Cysteine against Hyperglycaemia-Induced Cardiac Damage.
Topics: Acetylcysteine; Animals; Apoptosis; Cardiotonic Agents; Cell Line; Glucose; Hyperglycemia; Lipid Peroxidation; Metformin; Models, Biological; Myocytes, Cardiac; Oxidative Stress; Rats | 2019 |
High glucose-induced ROS accumulation is a critical regulator of ERK1/2-Akt-tuberin-mTOR signalling in RGC-5 cells.
Topics: Acetylcysteine; Animals; DNA, Mitochondrial; Enzyme Inhibitors; Gene Expression Regulation; Glucose; Human Umbilical Vein Endothelial Cells; Humans; Hyperglycemia; Inflammation; Interferon Regulatory Factor-3; Membrane Potential, Mitochondrial; Mice; Mitochondria; Mitogen-Activated Protein Kinase 3; NADPH Oxidases; Neurodegenerative Diseases; Oxidative Stress; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Retinal Ganglion Cells; RNA, Small Interfering; Signal Transduction; TOR Serine-Threonine Kinases; Tuberous Sclerosis Complex 2 Protein | 2020 |
Imbalance in the antioxidant defence system and pro-genotoxic status induced by high glucose concentrations: In vitro testing in human liver cells.
Topics: 4-Nitroquinoline-1-oxide; Acetylcysteine; Antioxidants; Cell Line, Tumor; Comet Assay; DNA Damage; Glucose; Glutathione Transferase; Heme Oxygenase-1; Humans; Hyperglycemia; Liver; Mutagens; Phospholipid Hydroperoxide Glutathione Peroxidase; Reactive Oxygen Species | 2020 |
NAC Supplementation of Hyperglycemic Rats Prevents the Development of Insulin Resistance and Improves Antioxidant Status but Only Alleviates General and Salivary Gland Oxidative Stress.
Topics: Acetylcysteine; Animals; Free Radical Scavengers; Hyperglycemia; Insulin Resistance; Male; Oxidative Stress; Rats; Rats, Wistar; Salivary Glands | 2020 |
High glucose suppresses autophagy through the AMPK pathway while it induces autophagy via oxidative stress in chondrocytes.
Topics: Acetylcysteine; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Autophagy; Chondrocytes; Diabetes Complications; Diabetes Mellitus; Glucose; Humans; Hyperglycemia; Mice; Oxidative Stress; Ribonucleotides | 2021 |
Cardioprotective potential of N-acetyl cysteine against hyperglycaemia-induced oxidative damage: a protocol for a systematic review.
Topics: Acetylcysteine; Cardiotonic Agents; Diabetic Cardiomyopathies; Humans; Hyperglycemia; Oxidative Stress; Research Design; Review Literature as Topic; Systematic Reviews as Topic; Treatment Outcome | 2017 |
Diabetes-induced oxidative stress mediates upregulation of RhoA/Rho kinase pathway and hypercontractility of gastric smooth muscle.
Topics: Acetylcysteine; Animals; Blotting, Western; Cells, Cultured; Diabetes Mellitus; Free Radical Scavengers; Gastric Mucosa; Gene Expression; Glucose; Hyperglycemia; Mice, Inbred C57BL; Mice, Obese; MicroRNAs; Muscle Contraction; Muscle, Smooth; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Stomach; Up-Regulation | 2017 |
High glucose induces inflammatory responses in HepG2 cells via the oxidative stress-mediated activation of NF-κB, and MAPK pathways in HepG2 cells.
Topics: Acetylcysteine; Free Radical Scavengers; Gene Expression Regulation; Glucose; Hep G2 Cells; Hepatocytes; Humans; Hyperglycemia; Interleukin-6; MAP Kinase Signaling System; NF-kappa B; Osmolar Concentration; Oxidative Stress; Phosphorylation; Plasminogen Activator Inhibitor 1; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Reactive Oxygen Species; Reproducibility of Results; Tumor Necrosis Factor-alpha | 2018 |
Beneficial effects of N-acetylcysteine on hepatic oxidative stress in streptozotocin-induced diabetic rats.
Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Diabetes Mellitus, Experimental; Fatty Acids; Hyperglycemia; Insulin; Liver; Male; Oxidative Stress; Rats, Wistar; Streptozocin; Triglycerides; Urea | 2018 |
N-Acetylcysteine alleviates gut dysbiosis and glucose metabolic disorder in high-fat diet-fed mice.
Topics: Acetylcysteine; Animals; Bacteria; Blood Glucose; Diet, High-Fat; Dysbiosis; Feces; Free Radical Scavengers; Gastrointestinal Microbiome; Glucose Intolerance; Glucose Metabolism Disorders; Hyperglycemia; Lipopolysaccharides; Mice, Inbred C57BL; RNA, Ribosomal, 16S; Sequence Analysis, DNA | 2019 |
Astragaloside IV protects against hyperglycemia-induced vascular endothelial dysfunction by inhibiting oxidative stress and Calpain-1 activation.
Topics: Acetylcysteine; Animals; Aorta, Thoracic; Biomarkers; Calpain; Cysteine Proteinase Inhibitors; Diabetes Mellitus, Experimental; Dipeptides; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Hyperglycemia; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Sprague-Dawley; Saponins; Streptozocin; Triterpenes; Vasodilation | 2019 |
Naringin inhibits ROS-activated MAPK pathway in high glucose-induced injuries in H9c2 cardiac cells.
Topics: Acetylcysteine; Animals; Anthracenes; Apoptosis; Butadienes; Cell Line; Cell Survival; Enzyme Inhibitors; Flavanones; Fruit; Glucose; Hyperglycemia; Imidazoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mitochondria; Mitogen-Activated Protein Kinase 3; Myocytes, Cardiac; Nitriles; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plant Extracts; Pyridines; Rats; Reactive Oxygen Species | 2014 |
Enhancement of cellular antioxidant-defence preserves diastolic dysfunction via regulation of both diastolic Zn2+ and Ca2+ and prevention of RyR2-leak in hyperglycemic cardiomyocytes.
Topics: Acetylcysteine; Animals; Antioxidants; Blood Glucose; Body Weight; Calcium; Diabetes Mellitus, Experimental; Diastole; Heart Ventricles; Hyperglycemia; In Vitro Techniques; Intracellular Space; Male; Myocardium; Myocytes, Cardiac; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Ryanodine Receptor Calcium Release Channel; Tacrolimus Binding Proteins; Zinc | 2014 |
GSH protects against oxidative stress and toxicity in VL-17A cells exposed to high glucose.
Topics: Acetylcysteine; Alcohol Dehydrogenase; Antimetabolites; Antioxidants; Apoptosis; Buthionine Sulfoximine; Cell Survival; Clone Cells; Cytochrome P-450 CYP2E1; Glucose; Glutathione; Hep G2 Cells; Hepatocytes; Humans; Hyperglycemia; Lactoylglutathione Lyase; Maleates; Oxidative Stress; Reactive Oxygen Species; Recombinant Proteins; Ursodeoxycholic Acid | 2015 |
NADPH oxidase-generated reactive oxygen species are required for stromal cell-derived factor-1α-stimulated angiogenesis.
Topics: Acetylcysteine; Animals; Antioxidants; Aorta; Azoles; Cattle; Cell Movement; Chemokine CXCL12; Dual-Specificity Phosphatases; Endothelial Cells; Endothelium, Vascular; Gene Knockdown Techniques; Hyperglycemia; Isoenzymes; Isoindoles; Membrane Proteins; Mitogen-Activated Protein Kinase 10; Mitogen-Activated Protein Kinase Phosphatases; NADPH Oxidases; Neovascularization, Physiologic; Organoselenium Compounds; Oxidation-Reduction; Reactive Oxygen Species; Signal Transduction | 2014 |
Melatonin prevents hyperglycemia in a model of sleep apnea.
Topics: Acetylcysteine; Animals; Antioxidants; Blood Glucose; Body Weight; Cholesterol; Disease Models, Animal; Free Radical Scavengers; Hyperglycemia; Hypoxia; Melatonin; Mice, Inbred BALB C; Sleep Apnea, Obstructive; Time Factors; Triglycerides | 2015 |
Partial inhibition of the ubiquitin-proteasome system ameliorates cardiac dysfunction following ischemia-reperfusion in the presence of high glucose.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Antioxidants; Autophagy; Diabetic Cardiomyopathies; Hyperglycemia; Inflammation Mediators; Isolated Heart Preparation; Leupeptins; Male; Myocardial Reperfusion Injury; Myocardium; Proteasome Inhibitors; Rats, Wistar; Superoxide Dismutase; Superoxide Dismutase-1; Time Factors | 2015 |
The Antioxidant N-Acetylcysteine Inhibits Inflammatory and Apoptotic Processes in Human Conjunctival Epithelial Cells in a High-Glucose Environment.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Blotting, Western; Cells, Cultured; Conjunctiva; Epithelial Cells; Flow Cytometry; Glucose; Humans; Hyperglycemia; Reactive Oxygen Species; Signal Transduction | 2015 |
Hyperbaric Oxygen Preconditioning Attenuates Hemorrhagic Transformation Through Reactive Oxygen Species/Thioredoxin-Interacting Protein/Nod-Like Receptor Protein 3 Pathway in Hyperglycemic Middle Cerebral Artery Occlusion Rats.
Topics: Acetylcysteine; Animals; Arterial Occlusive Diseases; Brain Infarction; Carrier Proteins; Cell Cycle Proteins; Cerebral Hemorrhage; Glucose; Hyperbaric Oxygenation; Hyperglycemia; Inflammasomes; Male; Matrix Metalloproteinase 9; Middle Cerebral Artery; Prospective Studies; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Cell Surface; RNA, Small Interfering; Signal Transduction | 2016 |
Resveratrol inhibits hyperglycemia-driven ROS-induced invasion and migration of pancreatic cancer cells via suppression of the ERK and p38 MAPK signaling pathways.
Topics: Acetylcysteine; Cell Line, Tumor; Cell Movement; Diabetes Complications; Flavonoids; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; Glucose; Humans; Hyperglycemia; Imidazoles; MAP Kinase Signaling System; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Pyridines; Reactive Oxygen Species; Resveratrol; Stilbenes | 2016 |
A steroid like phytochemical Antcin M is an anti-aging reagent that eliminates hyperglycemia-accelerated premature senescence in dermal fibroblasts by direct activation of Nrf2 and SIRT-1.
Topics: Acetylcysteine; Antioxidants; Antrodia; Apoptosis; Cell Cycle; Cell Proliferation; Cell Survival; Cellular Senescence; Cholestenones; Endothelial Cells; Fibroblasts; Gene Silencing; Glucose; Humans; Hyperglycemia; Medicine, Chinese Traditional; NF-E2-Related Factor 2; Oxidative Stress; Phosphorylation; Phytochemicals; Reactive Oxygen Species; Resveratrol; Retinoblastoma Protein; Sirtuin 1; Skin; Stilbenes; Triterpenes | 2016 |
High Glucose-Induced Oxidative Stress Mediates Apoptosis and Extracellular Matrix Metabolic Imbalances Possibly via p38 MAPK Activation in Rat Nucleus Pulposus Cells.
Topics: Acetylcysteine; Aggrecans; Animals; Apoptosis; Blotting, Western; Cell Survival; Cells, Cultured; Collagen Type II; Extracellular Matrix; Free Radical Scavengers; Glucose; Humans; Hyperglycemia; Matrix Metalloproteinase 3; Nucleus Pulposus; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Rats; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; SOX9 Transcription Factor; Tissue Inhibitor of Metalloproteinase-1 | 2016 |
N-acetylcysteine-mediated antioxidation prevents hyperglycemia-induced apoptosis and collagen synthesis in rat mesangial cells.
Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Apoptosis; Caspases; Cells, Cultured; Collagen; Cytochromes c; Enzyme Activation; Extracellular Matrix; Free Radical Scavengers; Gene Expression; Hyperglycemia; Malondialdehyde; Mesangial Cells; Poly(ADP-ribose) Polymerases; Rats; Reactive Oxygen Species; Transforming Growth Factor beta1 | 2009 |
Neuroprotective effect of N-acetylcysteine in the development of diabetic encephalopathy in streptozotocin-induced diabetes.
Topics: Acetylcholinesterase; Acetylcysteine; Animals; Brain; Brain Diseases; Cognition Disorders; Diabetes Mellitus, Experimental; Hyperglycemia; Lipid Peroxidation; Male; Maze Learning; Neuroprotective Agents; Oxidative Stress; Random Allocation; Rats; Rats, Wistar | 2008 |
N-acetylcysteine prevents glucose/glucose oxidase-induced oxidative stress, mitochondrial damage and apoptosis in H9c2 cells.
Topics: Acetylcysteine; Animals; Apoptosis; Blotting, Western; Cell Line; Cytochromes c; Dose-Response Relationship, Drug; Glucose; Glucose Oxidase; Hyperglycemia; Membrane Potential, Mitochondrial; Mitochondria, Heart; Myocytes, Cardiac; Oxidative Stress; Peroxynitrous Acid; Reactive Oxygen Species | 2009 |
Hyperglycemia-induced alterations in synaptosomal membrane fluidity and activity of membrane bound enzymes: beneficial effect of N-acetylcysteine supplementation.
Topics: Acetylcysteine; Animals; Antioxidants; Blood Glucose; Calcium-Transporting ATPases; Cerebral Cortex; Diabetes Mellitus, Experimental; Hyperglycemia; Intracellular Membranes; Lipid Peroxidation; Lipids; Male; Membrane Fluidity; Neuroprotective Agents; Protein Binding; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Synaptosomes | 2009 |
N-acetylcysteine inhibits hyperglycemia-induced oxidative stress and apoptosis markers in diabetic neuropathy.
Topics: Acetylcysteine; Animals; Apoptosis; Biomarkers; Blood Glucose; Diabetic Neuropathies; Hyperglycemia; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Wistar | 2010 |
Hyperglycemia perturbs biochemical networks in human trophoblast BeWo cells.
Topics: Acetylcysteine; Aromatase; Biochemical Phenomena; Cell Differentiation; Cell Line; Cluster Analysis; Dose-Response Relationship, Drug; Female; Gene Expression; Gene Expression Profiling; Glucose; Humans; Hyperglycemia; Metabolic Networks and Pathways; Oligonucleotide Array Sequence Analysis; Pregnancy; Trophoblasts | 2010 |
Contrast-induced nephrotoxicity: possible synergistic effect of stress hyperglycemia.
Topics: Acetylcysteine; Analysis of Variance; Animals; Apoptosis; Contrast Media; Dogs; Hyperglycemia; Kidney Diseases; Kidney Tubules; Necrosis; Osmolar Concentration; Oxidative Stress; Taurine | 2010 |
Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia.
Topics: Acetylcysteine; Adaptation, Physiological; Adaptor Proteins, Signal Transducing; Animals; Antioxidants; Aorta; Catalase; Cells, Cultured; Coronary Vessels; Cytoskeletal Proteins; Dietary Fats; Endothelium, Vascular; Gene Expression Regulation; Glutamate-Cysteine Ligase; Heme Oxygenase-1; Hydrogen Peroxide; Hyperglycemia; Kelch-Like ECH-Associated Protein 1; Male; Membrane Proteins; Mice; Mice, Inbred ICR; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Polyethylene Glycols; Reactive Oxygen Species | 2011 |
Hyperglycemia regulates MDR-1, drug accumulation and ROS levels causing increased toxicity of carboplatin and 5-fluorouracil in MCF-7 cells.
Topics: Acetylcysteine; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Carboplatin; Cell Line, Tumor; Female; Fluorouracil; Glucose; Humans; Hyperglycemia; Inhibitory Concentration 50; NF-kappa B; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Verapamil | 2011 |
Hyperglycaemia exacerbates choroidal neovascularisation in mice via the oxidative stress-induced activation of STAT3 signalling in RPE cells.
Topics: Acetylcysteine; Animals; Antioxidants; Choroid; Choroidal Neovascularization; Diabetes Mellitus, Experimental; DNA Damage; Epithelial Cells; Gene Expression; Hyperglycemia; Light Coagulation; Mice; Oxidative Stress; Phosphorylation; Reactive Oxygen Species; Retina; Retinal Pigment Epithelium; Severity of Illness Index; Signal Transduction; STAT3 Transcription Factor; Streptozocin; Tyrphostins; Vascular Endothelial Growth Factor A | 2012 |
Taurine may not alleviate hyperglycemia-mediated endoplasmic reticulum stress in human adipocytes.
Topics: Acetylcysteine; Adipocytes; Adiponectin; Cell Differentiation; Endoplasmic Reticulum Stress; Humans; Hyperglycemia; Leptin; Taurine; Taurochenodeoxycholic Acid; Thapsigargin | 2013 |
Apoptosis in human aortic endothelial cells induced by hyperglycemic condition involves mitochondrial depolarization and is prevented by N-acetyl-L-cysteine.
Topics: Acetylcysteine; Aorta; Apoptosis; Cells, Cultured; Endothelium, Vascular; Flow Cytometry; Fluorescence; Free Radical Scavengers; Humans; Hyperglycemia; Intracellular Membranes; Membrane Potentials; Mitochondria; Time Factors | 2002 |
N-acetylcysteine restores isoflurane-induced preconditioning against myocardial infarction during hyperglycemia.
Topics: Acetylcysteine; Anesthetics, Inhalation; Animals; Collateral Circulation; Coronary Circulation; Dogs; Female; Free Radical Scavengers; Hemodynamics; Hyperglycemia; Ischemic Preconditioning, Myocardial; Isoflurane; Male; Myocardial Infarction; Myocardium; Ventricular Function, Left | 2003 |
Glucose enhances human macrophage LOX-1 expression: role for LOX-1 in glucose-induced macrophage foam cell formation.
Topics: Acetylcysteine; Adult; Aged; Anti-Infective Agents; Antioxidants; Arteriosclerosis; Cells, Cultured; Curcumin; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Female; Flavonoids; Foam Cells; Gene Expression Regulation; Glucose; Glycation End Products, Advanced; Humans; Hyperglycemia; Macrophages; Male; MAP Kinase Signaling System; Mesylates; Middle Aged; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NF-kappa B; Nitriles; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Processing, Post-Translational; Pyrroles; Receptors, LDL; RNA, Messenger; Signal Transduction; Sulfones; Transcription Factor AP-1; Tumor Necrosis Factor-alpha | 2004 |
The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species.
Topics: 3T3-L1 Cells; 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Adenoviridae; Adipocytes; Animals; Blotting, Northern; Cell Differentiation; Deoxyguanosine; Diabetes Mellitus, Experimental; Dicarboxylic Acid Transporters; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Glucose; Hyperglycemia; Immunoblotting; Inflammation; Insulin; Interleukin-6; Membrane Potentials; Mice; Mitochondria; Oxidative Stress; Oxygen; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Streptozocin; Time Factors; Transcription, Genetic; Up-Regulation | 2005 |
Effects of N-acetylcysteine on sucrose-rich diet-induced hyperglycaemia, dyslipidemia and oxidative stress in rats.
Topics: Acetylcysteine; Animals; Antioxidants; Blood Glucose; Body Weight; Dietary Sucrose; Dyslipidemias; Glutathione; Glutathione Peroxidase; Hyperglycemia; Lipid Metabolism; Lipid Peroxides; Lipids; Liver; Male; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase | 2006 |
Antioxidants attenuate high glucose-induced hypertrophic growth in renal tubular epithelial cells.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Cell Cycle; Cell Line; Epithelial Cells; Extracellular Matrix; Glucose; Hyperglycemia; Hypertrophy; Janus Kinases; Kidney Tubules, Proximal; Mitogen-Activated Protein Kinase Kinases; Proto-Oncogene Proteins c-raf; Signal Transduction; STAT Transcription Factors; Swine; Taurine | 2007 |
Antidiabetic zinc(II)-N-acetyl-L-cysteine complex: evaluations of in vitro insulinomimetic and in vivo blood glucose-lowering activities.
Topics: Acetylcysteine; Adipocytes; Animals; Antioxidants; Blood Glucose; Blood Urea Nitrogen; Cholesterol; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Evaluation, Preclinical; Glucose Tolerance Test; Hemoglobins; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Mice; Mice, Knockout; Oxidative Stress; Rats; Rats, Wistar; Zinc | 2007 |
Cystic fibrosis of the pancreas.
Topics: Acetylcysteine; Anti-Bacterial Agents; Bronchi; Bronchial Diseases; Child; Cystic Fibrosis; Digestive System; Drainage; Fecal Impaction; Humans; Hyperglycemia; Intestinal Obstruction; Liver Cirrhosis; Lung; Lung Diseases; Meconium; Mucus; Pneumatosis Cystoides Intestinalis; Respiratory Function Tests; Respiratory Insufficiency; Respiratory Therapy; Respiratory Tract Diseases; Salivary Glands; Sweat | 1966 |
Acetaminophen-induced hepatic glycogen depletion and hyperglycemia in mice.
Topics: Acetaminophen; Acetylcysteine; Animals; Chemical and Drug Induced Liver Injury; Glutathione; Hyperglycemia; Liver Glycogen; Male; Mice | 1983 |
Massive sulfasalazine and paracetamol ingestion causing acidosis, hyperglycemia, coagulopathy, and methemoglobinemia.
Topics: Acetaminophen; Acetylcysteine; Acidosis, Lactic; Acute Disease; Adult; Anti-Inflammatory Agents; Blood Coagulation Disorders; Blood Platelets; Drug Combinations; Drug Overdose; Humans; Hyperglycemia; Infusions, Intravenous; Male; Methemoglobinemia; Methylene Blue; Partial Thromboplastin Time; Sodium Bicarbonate; Suicide, Attempted; Sulfasalazine | 1998 |
Induction of glycation suppresses glucokinase gene expression in HIT-T15 cells.
Topics: Acetylcysteine; Cell Line; DNA; DNA-Binding Proteins; Gene Expression; Glucokinase; Glycosylation; Guanidines; Homeodomain Proteins; Humans; Hyperglycemia; Islets of Langerhans; Nuclear Respiratory Factor 1; Phosphorylation; Promoter Regions, Genetic; Reactive Oxygen Species; Ribose; RNA, Messenger; Trans-Activators; Transcription Factors; Transcription, Genetic; Transfection | 1999 |
Molecular mechanisms of tumor necrosis factor alpha gene expression in monocytic cells via hyperglycemia-induced oxidant stress-dependent and -independent pathways.
Topics: Acetylcysteine; Cell Line; Gene Expression Regulation; Glucose; Humans; Hyperglycemia; Imidazoles; Luminescent Measurements; Mitogen-Activated Protein Kinases; Monocytes; NF-kappa B; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Proline; Pyridines; Reactive Oxygen Species; RNA, Messenger; Thiocarbamates; Transcription Factor AP-1; Transcription, Genetic; Tumor Necrosis Factor-alpha; U937 Cells | 2000 |
Pancytopenia, hyperglycemia, shock, coma, rhabdomyolysis, and pancreatitis associated with acetaminophen poisoning.
Topics: Acetaminophen; Acetylcysteine; Adult; Anti-Inflammatory Agents, Non-Steroidal; Coma; Diagnosis, Differential; Drug Overdose; Fatal Outcome; Female; Free Radical Scavengers; Humans; Hyperglycemia; Liver Failure; Pancreatitis; Pancytopenia; Renal Insufficiency; Rhabdomyolysis; Shock; Suicide, Attempted | 2001 |
Contamination of a specimen with N-acetyl cysteine infusion: a cause of spurious ketonaemia and hyperglycaemia.
Topics: Acetylcysteine; Acidosis; Adult; False Positive Reactions; Female; Humans; Hyperglycemia; Ketone Bodies; Reagent Strips | 1989 |