acetylcysteine has been researched along with Huntington Disease in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lindholm, D; Myöhänen, TT; Norrbacka, S | 1 |
| Francis, PS; Frazier, AE; Gray, LJ; Hannan, AJ; McGee, SL; Renoir, T; Smith, ZM; Thorburn, DR; Wright, DJ | 1 |
| Berk, M | 1 |
| Kamboj, SS; Mehrotra, A; Sandhir, R; Sood, A | 1 |
| Johnson, WM; Mieyal, JJ; Wilson-Delfosse, AL | 1 |
| Arrigo, AP; Currie, RW; Firdaus, WJ; Giuliano, P; Kretz-Remy, C; Wyttenbach, A | 1 |
| Carmichael, J; Furlong, RA; Narain, Y; Rankin, J; Rubinsztein, DC; Swartz, J; Wyttenbach, A | 1 |
| Banks, A; Butterfield, DA; Fontaine, MA; Geddes, JW | 1 |
| Boeddrich, A; Lehrach, H; Lueder, G; Lurz, R; Scherzinger, E; Waelter, S; Wanker, EE | 1 |
| Avila, J; Hen, R; Hernández, F; Lucas, JJ; Martín-Aparicio, E; Yamamoto, A | 1 |
1 review(s) available for acetylcysteine and Huntington Disease
| Article | Year |
|---|---|
Dysregulation of glutathione homeostasis in neurodegenerative diseases.
Topics: Acetylcysteine; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Friedreich Ataxia; Glutathione; Homeostasis; Humans; Huntington Disease; Neurodegenerative Diseases; Parkinson Disease | 2012 |
9 other study(ies) available for acetylcysteine and Huntington Disease
| Article | Year |
|---|---|
Prolyl oligopeptidase inhibition reduces PolyQ aggregation and improves cell viability in cellular model of Huntington's disease.
Topics: Acetylcysteine; Biocatalysis; Cell Survival; Cysteine Proteinase Inhibitors; HeLa Cells; Humans; Huntingtin Protein; Huntington Disease; Peptides; Proline; Prolyl Oligopeptidases; Proteasome Endopeptidase Complex; Protein Aggregates; Protein Aggregation, Pathological; Serine Endopeptidases; Trinucleotide Repeats | 2019 |
N-Acetylcysteine improves mitochondrial function and ameliorates behavioral deficits in the R6/1 mouse model of Huntington's disease.
Topics: Acetylcysteine; Animals; Behavior, Animal; Brain; Disease Models, Animal; Disease Progression; Excitatory Amino Acid Transporter 2; Free Radical Scavengers; Gait; Huntington Disease; Mice; Mice, Transgenic; Mitochondria; Motor Activity; Organ Size; Oxidative Stress | 2015 |
N-Acetylcysteine for Huntington's?
Topics: Acetylcysteine; Affect; Depression; Female; Humans; Huntington Disease; Middle Aged; Psychiatric Status Rating Scales; Quality of Life; Treatment Outcome | 2015 |
N-Acetylcysteine reverses mitochondrial dysfunctions and behavioral abnormalities in 3-nitropropionic acid-induced Huntington's disease.
Topics: Acetylcysteine; Animals; Behavior, Animal; Caspase 3; Cognition; Corpus Striatum; Female; Free Radical Scavengers; Huntington Disease; Lipid Peroxidation; Mitochondria; Motor Skills; Nitro Compounds; Oxidative Stress; Propionates; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Tumor Suppressor Protein p53 | 2012 |
Huntingtin inclusion bodies are iron-dependent centers of oxidative events.
Topics: Acetylcysteine; Animals; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Deferoxamine; Exons; Heat-Shock Proteins; Huntington Disease; Inclusion Bodies; Iron; Microscopy, Confocal; Oxidation-Reduction; Phenanthridines; Rats; Recombinant Fusion Proteins | 2006 |
Effects of heat shock, heat shock protein 40 (HDJ-2), and proteasome inhibition on protein aggregation in cellular models of Huntington's disease.
Topics: Acetylcysteine; Animals; Blotting, Western; Carrier Proteins; Cell Death; COS Cells; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Exons; Heat-Shock Proteins; HSP40 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; Huntington Disease; Immunohistochemistry; Multienzyme Complexes; Peptides; Plasmids; Proteasome Endopeptidase Complex; Rats; Temperature; Time Factors; Transfection; Tumor Cells, Cultured | 2000 |
Effect of exogenous and endogenous antioxidants on 3-nitropionic acid-induced in vivo oxidative stress and striatal lesions: insights into Huntington's disease.
Topics: Acetylcysteine; Animals; Antioxidants; Cerebral Cortex; Corpus Striatum; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Glutathione; Huntington Disease; Male; Membrane Proteins; Nitro Compounds; Oxidative Stress; Propionates; Rats; Rats, Sprague-Dawley; Synaptic Membranes; Synaptosomes | 2000 |
Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation.
Topics: 14-3-3 Proteins; Acetylcysteine; alpha-Synuclein; Carrier Proteins; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Endoplasmic Reticulum Chaperone BiP; Exons; Heat-Shock Proteins; Humans; Huntingtin Protein; Huntington Disease; Immunoblotting; Inclusion Bodies; Membrane Proteins; Microscopy, Fluorescence; Models, Biological; Molecular Chaperones; Multienzyme Complexes; Mutation; Nerve Tissue Proteins; Nuclear Proteins; Peptide Fragments; Poly(A)-Binding Proteins; Proteasome Endopeptidase Complex; Proteins; Recombinant Fusion Proteins; RNA-Binding Proteins; Synucleins; T-Cell Intracellular Antigen-1; Transgenes; Tyrosine 3-Monooxygenase; Vimentin | 2001 |
Proteasomal-dependent aggregate reversal and absence of cell death in a conditional mouse model of Huntington's disease.
Topics: Acetylcysteine; Animals; Behavior, Animal; Cell Death; Cell Survival; Cells, Cultured; Corpus Striatum; Cysteine Endopeptidases; Disease Models, Animal; Gene Silencing; Genes, Dominant; Huntingtin Protein; Huntington Disease; Locomotion; Macromolecular Substances; Mice; Mice, Neurologic Mutants; Multienzyme Complexes; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Phenotype; Proteasome Endopeptidase Complex; Remission Induction; Tetracycline; Transgenes; Ubiquitin | 2001 |