acetylcysteine and Hepatic Encephalopathy

acetylcysteine has been researched along with Hepatic Encephalopathy in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19906 (14.29)18.7374
1990's14 (33.33)18.2507
2000's8 (19.05)29.6817
2010's13 (30.95)24.3611
2020's1 (2.38)2.80

Authors

AuthorsStudies
Nguyen, T; Siu, JT; Turgeon, RD1
Bunchorntavakul, C; Reddy, KR1
Amathieu, R; Chemit, M; Compagnon, P; Costentin, C; Dhonneur, G; Levesque, E; Merle, JC1
Bajaj, JS; Cheng, J; Lee, WM; Mirshahi, F; Reisch, J; Sanyal, AJ; Stravitz, RT1
Baillie, GS; Boomkamp, SD; Tsakiris, S; Zarros, A1
Koch, A; Streetz, KL; Tacke, F; Trautwein, C1
Hauffe, T; Kupferschmidt, H; Mayer, F1
Kodali, S; McGuire, BM1
Mas, A; Nogué, S1
Davern, TJ; Fontana, RJ; Hynan, LS; Larson, AM; Lee, WM; McCashland, T; Murray, NG; Reisch, JS; Robuck, PR; Rossaro, L; Stravitz, RT1
Trotter, JF1
Bémeur, C; Butterworth, RF; Desjardins, P; Vaquero, J1
Bagdure, D; Heard, K; Monte, A; Wang, GS1
Butterworth, RF1
Alonso, E; Belle, SH; Bucuvalas, J; Dhawan, A; Doo, E; Elisofon, S; Horslen, S; Karpen, S; Kerkar, N; Lawlor, S; Lobritto, S; Lopez, MJ; Narkewicz, MR; Ng, V; Olio, DD; Rand, E; Robuck, PR; Rodriguez-Baez, N; Romero, R; Rosenthal, P; Rudnick, D; Schwarz, K; Shneider, BL; Squires, RH; Subbarao, G1
Dhanda, S; Kaur, S; Sandhir, R1
Abeysekera, RA; Illangasekera, U; Jayalath, T; Kularatne, SA; Sandeepana, AG1
McGuire, BM1
Ytrebø, LM1
Aladag, M; Ara, C; Ciralik, H; Demirel, U; Firat, S; Harputluoglu, MM; Hilmioglu, F; Karincaoglu, M; Temel, I1
Björnsson, E1
Black, M1
Atwood, SJ1
Makin, AJ; Wendon, J; Williams, R1
Kirsh, BM; Lam, N; Layden, TJ; Wiley, TE1
Harrison, PM; Keays, R; Wendon, JA; Williams, R1
Cheung, L; Meyer, KC; Potts, RG1
Mutimer, D; Neuberger, J1
Hegarty, JE; Mulcahy, HE1
Harrison, P; Wendon, J; Williams, R1
Fellay, M; Kehtari, R1
Chan, TY1
Bondesen, S; Christensen, E; Ott, P; Schiødt, FV1
Bray, GP; Harrison, PM; O'Grady, JG; Tredger, JM; Williams, R1
Alexander, GJ; Gimson, AE; Harrison, PM; Wendon, JA; Williams, R1
Alexander, GJ; Forbes, A; Gove, C; Harrison, PM; Keays, R; Wendon, JA; Williams, R1
Alexander, GJ; Bray, GP; Harrison, PM; Keays, R; Williams, R1
Harvey, JM; Jones, AF; Vale, JA1
Davenport, A; Finn, R1
Alp, MH; Hickman, R1
Read, RB; Tredger, JM; Williams, R1

Reviews

14 review(s) available for acetylcysteine and Hepatic Encephalopathy

ArticleYear
N-acetylcysteine for non-paracetamol (acetaminophen)-related acute liver failure.
    The Cochrane database of systematic reviews, 2020, Dec-09, Volume: 12

    Topics: Acetylcysteine; Adolescent; Adult; Bias; Cause of Death; Child; Child, Preschool; Hepatic Encephalopathy; Humans; Infant; Infant, Newborn; Liver Failure, Acute; Liver Transplantation; Placebos; Prognosis; Randomized Controlled Trials as Topic

2020
Acute Liver Failure.
    Clinics in liver disease, 2017, Volume: 21, Issue:4

    Topics: Acetylcysteine; Brain Edema; Chemical and Drug Induced Liver Injury; Clinical Protocols; Critical Care; Disease Management; Diuretics, Osmotic; Free Radical Scavengers; Hepatic Encephalopathy; Humans; Intracranial Hypertension; Liver Failure, Acute; Liver Transplantation; Mannitol; Saline Solution, Hypertonic; Time Factors

2017
[Severe toxic acute liver failure: etiology and treatment].
    Annales francaises d'anesthesie et de reanimation, 2013, Volume: 32, Issue:6

    Topics: Acetaminophen; Acetylcysteine; Acute Kidney Injury; Anti-Infective Agents; Blood Coagulation Disorders; Chemical and Drug Induced Liver Injury; Cholestasis; Combined Modality Therapy; Diagnosis, Differential; Disease Management; Hepatic Encephalopathy; Hepatitis, Viral, Human; Humans; Illicit Drugs; Liver Failure, Acute; Liver Function Tests; Liver Transplantation; Mushroom Poisoning; Neurologic Examination; Occupational Diseases; Respiratory Insufficiency; Sepsis; Shock; Time Factors; Valproic Acid

2013
[Acute liver failure. Diagnosis and therapy].
    Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2013, Volume: 108, Issue:8

    Topics: Acetylcysteine; Chemical and Drug Induced Liver Injury; Hepatic Encephalopathy; Humans; Liver Failure, Acute; Liver Transplantation; Multiple Organ Failure; Nucleosides; Nucleotides; Organ Dysfunction Scores; Prognosis

2013
[Poisoning with Amanita mushrooms].
    Praxis, 2013, Dec-11, Volume: 102, Issue:25

    Topics: Acetylcysteine; Adult; Amanita; Amanitins; Cause of Death; Combined Modality Therapy; Critical Care; Diagnosis, Differential; Hepatic Encephalopathy; Humans; Liver Function Tests; Liver Transplantation; Male; Mushroom Poisoning; Prognosis; Silybin; Silymarin

2013
Diagnosis and Management of Hepatic Encephalopathy in Fulminant Hepatic Failure.
    Clinics in liver disease, 2015, Volume: 19, Issue:3

    Topics: Acetylcysteine; Ammonia; Brain Edema; Free Radical Scavengers; Gastrointestinal Agents; Hepatic Encephalopathy; Humans; Intracranial Pressure; Lactulose; Liver Failure, Acute; Neuroimaging; Neuropsychological Tests; Nutritional Support; Rifamycins; Rifaximin

2015
Practical management of acute liver failure in the Intensive Care Unit.
    Current opinion in critical care, 2009, Volume: 15, Issue:2

    Topics: Acetylcysteine; Biopsy, Needle; Brain Edema; Free Radical Scavengers; Hepatic Encephalopathy; Humans; Intensive Care Units; Liver Failure, Acute; Liver Transplantation; Renal Insufficiency; United States

2009
Hepatic encephalopathy: a central neuroinflammatory disorder?
    Hepatology (Baltimore, Md.), 2011, Volume: 53, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Animals; Brain Edema; Hepatic Encephalopathy; Humans; Hypothermia, Induced; Liver Failure, Acute; Minocycline

2011
The critically ill liver patient: fulminant hepatic failure.
    Seminars in gastrointestinal disease, 2003, Volume: 14, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Brain Edema; Critical Illness; Diagnosis, Differential; Female; Free Radical Scavengers; Hepatic Encephalopathy; Humans; Liver Function Tests; Liver Transplantation; Middle Aged; Prognosis

2003
Hepatotoxicity associated with antiepileptic drugs.
    Acta neurologica Scandinavica, 2008, Volume: 118, Issue:5

    Topics: Acetylcysteine; Animals; Anticonvulsants; Autoimmune Diseases; Carnitine; Chemical and Drug Induced Liver Injury; Disseminated Intravascular Coagulation; Hepatic Encephalopathy; Hepatocytes; Humans; Liver; Liver Diseases

2008
Acetaminophen hepatotoxicity.
    Gastroenterology, 1980, Volume: 78, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Cysteamine; Cysteine; Glutathione; Hepatic Encephalopathy; Humans; Liver; Liver Function Tests; Methionine

1980
Diagnosis and management of fulminant hepatic failure.
    Comprehensive therapy, 1995, Volume: 21, Issue:4

    Topics: Acetylcysteine; Adrenal Cortex Hormones; Artificial Organs; Blood Coagulation Disorders; Brain Edema; Chemical and Drug Induced Liver Injury; Hepatic Encephalopathy; Hepatitis, Viral, Human; Humans; Liver; Prognosis; Renal Insufficiency; Risk Factors

1995
Paracetamol hepatotoxicity.
    Irish journal of medical science, 1993, Volume: 162, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Chemical and Drug Induced Liver Injury; Drug Overdose; Hepatic Encephalopathy; Humans; Intubation; Liver Diseases; Prognosis; Stomach

1993
[Focus: fulminant and subfulminant hepatic insufficiency].
    Revue medicale de la Suisse romande, 1996, Volume: 116, Issue:6

    Topics: Acetylcysteine; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Critical Care; Hepatic Encephalopathy; Hepatitis, Viral, Human; Humans; Hypoxia; Liver Failure, Acute; Liver Transplantation; Prognosis

1996

Trials

5 trial(s) available for acetylcysteine and Hepatic Encephalopathy

ArticleYear
Effects of N-acetylcysteine on cytokines in non-acetaminophen acute liver failure: potential mechanism of improvement in transplant-free survival.
    Liver international : official journal of the International Association for the Study of the Liver, 2013, Volume: 33, Issue:9

    Topics: Acetylcysteine; Cytokines; Enzyme-Linked Immunosorbent Assay; Hepatic Encephalopathy; Humans; Liver Failure, Acute; Logistic Models

2013
Intravenous N-acetylcysteine improves transplant-free survival in early stage non-acetaminophen acute liver failure.
    Gastroenterology, 2009, Volume: 137, Issue:3

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Double-Blind Method; Female; Hepatic Encephalopathy; Humans; Infusions, Intravenous; Liver Failure, Acute; Liver Transplantation; Male; Middle Aged; Survival Rate; Young Adult

2009
Intravenous N-acetylcysteine in pediatric patients with nonacetaminophen acute liver failure: a placebo-controlled clinical trial.
    Hepatology (Baltimore, Md.), 2013, Volume: 57, Issue:4

    Topics: Acetylcysteine; Adolescent; Child; Child, Preschool; Double-Blind Method; Female; Free Radical Scavengers; Hepatic Encephalopathy; Humans; Infant; Infant, Newborn; Infusions, Intravenous; Liver Failure, Acute; Liver Transplantation; Male; Severity of Illness Index; Survival Rate; Treatment Outcome

2013
Improvement by acetylcysteine of hemodynamics and oxygen transport in fulminant hepatic failure.
    The New England journal of medicine, 1991, Jun-27, Volume: 324, Issue:26

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Biological Transport; Chemical and Drug Induced Liver Injury; Drug Overdose; Female; Hemodynamics; Hepatic Encephalopathy; Hepatitis C; Hepatitis, Alcoholic; Humans; Male; Middle Aged; Oxygen; Oxygen Consumption

1991
Intravenous acetylcysteine in paracetamol induced fulminant hepatic failure: a prospective controlled trial.
    BMJ (Clinical research ed.), 1991, Oct-26, Volume: 303, Issue:6809

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Chemical and Drug Induced Liver Injury; Drug Overdose; Female; Hepatic Encephalopathy; Humans; Infusions, Intravenous; Liver Diseases; London; Male; Middle Aged; Prospective Studies; Prothrombin Time; Survival Rate

1991

Other Studies

23 other study(ies) available for acetylcysteine and Hepatic Encephalopathy

ArticleYear
The extent and the nature of the cholinergic contribution to the hepatic encephalopathy-induced cognitive impairment.
    Free radical biology & medicine, 2013, Volume: 65

    Topics: Acetylcysteine; Animals; Bile Ducts; Cognition Disorders; Hepatic Encephalopathy; Male; Oxidative Stress

2013
[N-acetylcisteine in Amanita phalloides poisoning].
    Medicina clinica, 2009, Oct-03, Volume: 133, Issue:12

    Topics: Acetylcysteine; Amanita; Antidotes; Clinical Trials as Topic; Free Radical Scavengers; Hepatic Encephalopathy; Hepatic Insufficiency; Humans; Liver Transplantation; Multicenter Studies as Topic; Mushroom Poisoning; Prothrombin Time

2009
N-acetylcysteine attenuates cerebral complications of non-acetaminophen-induced acute liver failure in mice: antioxidant and anti-inflammatory mechanisms.
    Metabolic brain disease, 2010, Volume: 25, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Animals; Antioxidants; Azoxymethane; Brain Edema; Carcinogens; Cytokines; Disease Models, Animal; Hepatic Encephalopathy; Inflammation; Inflammation Mediators; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Oxidative Stress

2010
Hepatic failure despite early acetylcysteine following large acetaminophen-diphenhydramine overdose.
    Pediatrics, 2011, Volume: 127, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Analgesics, Non-Narcotic; Child; Cholinergic Antagonists; Diphenhydramine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Overdose; Female; Free Radical Scavengers; Half-Life; Hepatic Encephalopathy; Humans; Infusions, Intravenous; Intensive Care Units, Pediatric; International Normalized Ratio; Liver Failure; Liver Function Tests; Metabolic Clearance Rate; Suicide, Attempted

2011
Preventive effect of N-acetyl-L-cysteine on oxidative stress and cognitive impairment in hepatic encephalopathy following bile duct ligation.
    Free radical biology & medicine, 2013, Volume: 56

    Topics: Acetylcysteine; Animals; Bile Ducts; Cognition Disorders; Hepatic Encephalopathy; Male; Oxidative Stress; Rats; Rats, Wistar

2013
Successful use of intravenous N-acetylcysteine in dengue haemorrhagic fever with acute liver failure.
    The Ceylon medical journal, 2012, Volume: 57, Issue:4

    Topics: Acetylcysteine; Administration, Intravenous; Female; Free Radical Scavengers; Hepatic Encephalopathy; Humans; Liver Failure, Acute; Middle Aged; Severe Dengue; Treatment Outcome

2012
A lowered incidence of severe encephalopathy and cardiovascular dysfunction.
    Critical care medicine, 2005, Volume: 33, Issue:5

    Topics: Acetylcysteine; Animals; Antioxidants; Hepatic Encephalopathy; Humans; Rats; Telencephalon

2005
Protective effects of Gingko biloba on thioacetamide-induced fulminant hepatic failure in rats.
    Human & experimental toxicology, 2006, Volume: 25, Issue:12

    Topics: Acetylcysteine; Alanine Transaminase; Ammonia; Animals; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drugs, Chinese Herbal; Free Radical Scavengers; Ginkgo biloba; Hepatic Encephalopathy; Liver; Male; Necrosis; Oxidative Stress; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Severity of Illness Index; Thioacetamide; Thiobarbituric Acid Reactive Substances

2006
The laboratory in the diagnosis and management of acetaminophen and salicylate intoxications.
    Pediatric clinics of North America, 1980, Volume: 27, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Acid-Base Imbalance; Aspirin; Child, Preschool; Female; Hepatic Encephalopathy; Humans; Infant; Liver; Male; Poisoning; Salicylates; Time Factors

1980
A 7-year experience of severe acetaminophen-induced hepatotoxicity (1987-1993).
    Gastroenterology, 1995, Volume: 109, Issue:6

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Brain Edema; Chi-Square Distribution; Drug Overdose; Female; Hepatic Encephalopathy; Humans; Liver; Liver Failure; Liver Transplantation; Male; Middle Aged; Prognosis; Retrospective Studies; Risk Factors; Survival Rate

1995
Cerebral blood flow and metabolism in fulminant liver failure.
    Hepatology (Baltimore, Md.), 1994, Volume: 19, Issue:6

    Topics: Acetaminophen; Acetylcysteine; Adult; Blood Flow Velocity; Brain; Brain Edema; Drug Overdose; Epoprostenol; Female; Glucose; Hepatic Encephalopathy; Hepatitis, Viral, Human; Humans; Lactates; Male; Mannitol; Middle Aged; Oxygen; Regional Blood Flow; Respiration, Artificial

1994
Acetaminophen treatment nomogram.
    The New England journal of medicine, 1994, Jun-30, Volume: 330, Issue:26

    Topics: Acetaminophen; Acetylcysteine; Adult; Drug Overdose; Female; Hepatic Encephalopathy; Humans; Reference Values

1994
Acute liver failure: improving outcome despite a paucity of treatment options.
    The Quarterly journal of medicine, 1993, Volume: 86, Issue:7

    Topics: Acetaminophen; Acetylcysteine; Acute Disease; Hepatic Encephalopathy; Humans; Liver Transplantation; Prognosis

1993
Evidence of increased guanylate cyclase activation by acetylcysteine in fulminant hepatic failure.
    Hepatology (Baltimore, Md.), 1996, Volume: 23, Issue:5

    Topics: Acetylcysteine; Adolescent; Adult; Atrial Natriuretic Factor; Cyclic AMP; Cyclic GMP; Enzyme Activation; Female; Guanylate Cyclase; Hemodynamics; Hepatic Encephalopathy; Humans; Male; Middle Aged; Nitric Oxide; Oxygen; Oxygen Consumption

1996
The epidemiology of acetaminophen (paracetamol) poisoning in Hong Kong.
    Veterinary and human toxicology, 1996, Volume: 38, Issue:6

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Analgesics, Non-Narcotic; Cohort Studies; Female; Free Radical Scavengers; Hepatic Encephalopathy; Humans; Longitudinal Studies; Male; Poisoning

1996
The value of plasma acetaminophen half-life in antidote-treated acetaminophen overdosage.
    Clinical pharmacology and therapeutics, 2002, Volume: 71, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Analysis of Variance; Antidotes; Drug Overdose; Female; Half-Life; Hepatic Encephalopathy; Humans; Liver Failure, Acute; Male; Middle Aged; Prospective Studies; Statistics, Nonparametric

2002
Long-term anticonvulsant therapy worsens outcome in paracetamol-induced fulminant hepatic failure.
    Human & experimental toxicology, 1992, Volume: 11, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aged; Anticonvulsants; Drug Interactions; Drug Overdose; Female; Hepatic Encephalopathy; Humans; Longitudinal Studies; Male; Middle Aged; Prognosis; Risk Factors

1992
Improved outcome of paracetamol-induced fulminant hepatic failure by late administration of acetylcysteine.
    Lancet (London, England), 1990, Jun-30, Volume: 335, Issue:8705

    Topics: Acetaminophen; Acetylcysteine; Acute Disease; Adult; Aspartate Aminotransferases; Drug Evaluation; Female; Hepatic Encephalopathy; Humans; Infusions, Intravenous; Liver; Male; Necrosis; Prognosis; Prothrombin Time; Retrospective Studies; Time Factors

1990
Acetylcysteine in paracetamol poisoning.
    Lancet (London, England), 1990, Oct-13, Volume: 336, Issue:8720

    Topics: Acetaminophen; Acetylcysteine; Hepatic Encephalopathy; Humans; Prognosis; Time Factors

1990
Hypophosphataemia and phosphaturia in paracetamol poisoning.
    Lancet (London, England), 1989, Sep-09, Volume: 2, Issue:8663

    Topics: Acetaminophen; Acetylcysteine; Adult; Chemical and Drug Induced Liver Injury; Evaluation Studies as Topic; Female; Glucose; Hepatic Encephalopathy; Humans; Male; Phosphates; Potassium; Severity of Illness Index

1989
Paracetamol (acetaminophen) poisoning resulting in acute renal failure without hepatic coma.
    Nephron, 1988, Volume: 50, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Acute Kidney Injury; Adult; Female; Hepatic Encephalopathy; Humans; Kidney Tubular Necrosis, Acute; Male

1988
The effect of prostaglandins, branched-chain amino acids and other drugs on the outcome of experimental acute porcine hepatic failure.
    Journal of hepatology, 1987, Volume: 4, Issue:1

    Topics: Acetylcysteine; Amino Acids, Branched-Chain; Amino Acids, Essential; Animals; Carbon Tetrachloride; Cholestyramine Resin; Disease Models, Animal; Hepatic Encephalopathy; Phosphatidylcholines; Prostaglandins; Silymarin; Swine

1987
Analysis of factors responsible for continuing mortality after paracetamol overdose.
    Human toxicology, 1986, Volume: 5, Issue:3

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Alcoholism; Antidotes; Dextropropoxyphene; Disseminated Intravascular Coagulation; Drug Combinations; Hepatic Encephalopathy; Humans; Liver Function Tests; Male; Methionine; Retrospective Studies

1986