acetylcysteine and Heart Diseases

acetylcysteine has been researched along with Heart Diseases in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19903 (11.11)18.7374
1990's3 (11.11)18.2507
2000's8 (29.63)29.6817
2010's11 (40.74)24.3611
2020's2 (7.41)2.80

Authors

AuthorsStudies
Chan, AWH; Chan, DPC; Chan, JYW; Ji, X; Lee, SMY; Lee, SS; Leung, RKK; Li, J; Ng, PCI; Ren, Z; Wang, R; Xu, Y; Yew, WW; Zheng, J1
He, YL; Li, XM; Nie, F; Xiong, Y; Zhou, XK1
Gharibeh, L; Harper, ME; Ichim, B; Kanaan, GN; Maharsy, W; Marshall, P; Menzies, K; Nemer, M; Patten, DA; Reunov, A; Veinot, J; Xuan, JY1
Braz, LG; El Dib, R; Escudero, J; Hayes, J; Johnston, BC; Pereira, JEG1
Bai, D; Gao, Y; Ge, L; Lu, X; Wang, H; Yang, G1
El Kiki, SM; Hasan, HF; Mansour, HH1
Chen, L; He, J; Li, J; Lin, XL; Liu, J; Liu, MH; Tan, TP; Tian, W; Wu, SJ; Yu, S; Yuan, C; Zhang, Y1
Chandra, J; Egas-Bejar, DE; Fulbright, JM; Huh, WW1
Ilic, M; Jakovljevic, V; Joksimovic, J; Mitrovic, S; Orescanin-Dusic, Z; Rosic, G; Selakovic, D; Srejovic, I; Tatalović, N; Zivkovic, V1
Angioli, P; Bolognese, L; Carrera, A; Ducci, K; Falsini, G; Grotti, S; Liistro, F; Limbruno, U; Picchi, A; Pierli, C1
Amauchi, JF; Cataneo, AC; Ebaid, GX; Fernandes, AA; Novelli, EL; Rocha, KK; Seiva, FR; Souza, G1
Arya, S; Contractor, H; Gauge, V; Nabi, S; Naqvi, N; Titu, H1
Islam, KN; Koch, WJ1
Benjamin, IJ; Brewer, AC; Murray, TV; Mustafi, SB; Rajasekaran, NS1
Ghelfi, E; González-Flecha, B; Lawrence, J; Rhoden, CR; Wellenius, GA1
Krizova, B; Sochman, J1
Guo, Z; McNeill, JH; Nagareddy, PR; Xia, Z; Yeung, E; Yuen, V1
Bortone, F; Ceriani, R; Fiorentini, C; Juliano, G; Marenzi, G; Salvi, L; Sisillo, E; Veglia, F1
Bouman, CC; Schultz, MJ1
Litovitz, TL1
Giese, C; Hannemann, L; Meier-Hellmann, A; Reinhart, K; Schaffartzik, W; Specht, M; Spies, C1
Buikema, H; Crijns, HJ; de Zeeuw, D; Monnink, SH; Tio, RA; van Gilst, WH1
Gustafson, DL; Pritsos, CA; Sokoloff, M1
Monti, E; Paracchini, L; Perletti, G; Piccinini, F1
Ferrans, VJ; Herman, EH1
Carnimeo, N; Iaia, E1

Reviews

3 review(s) available for acetylcysteine and Heart Diseases

ArticleYear
N-acetylcysteine use among patients undergoing cardiac surgery: A systematic review and meta-analysis of randomized trials.
    PloS one, 2019, Volume: 14, Issue:5

    Topics: Acetylcysteine; Biomarkers; Cardiac Surgical Procedures; Heart Diseases; Humans; Mortality; Odds Ratio; Prognosis; Publication Bias; Randomized Controlled Trials as Topic; Treatment Outcome; Workflow

2019
Reductive stress linked to small HSPs, G6PD, and Nrf2 pathways in heart disease.
    Antioxidants & redox signaling, 2013, Mar-20, Volume: 18, Issue:9

    Topics: Acetylcysteine; alpha-Crystallin B Chain; Animals; Antioxidants; Catalase; Disease Models, Animal; Early Diagnosis; Glucosephosphate Dehydrogenase; Glutathione; Heart Diseases; Heat-Shock Proteins; Humans; Mice; Models, Cardiovascular; Molecular Chaperones; Neoplasm Proteins; NF-E2-Related Factor 2; Peroxidases; Precision Medicine; Reactive Nitrogen Species; Reactive Oxygen Species; Recombinant Fusion Proteins; Superoxide Dismutase; Thioredoxins

2013
The anecdotal antidotes.
    Emergency medicine clinics of North America, 1984, Volume: 2, Issue:1

    Topics: Acetylcysteine; Adult; Aged; Animals; Antidotes; Child; Cimetidine; Female; Ferrocyanides; Folic Acid; Heart Diseases; Humans; Magnesium; Male; Middle Aged; Naloxone; Niacinamide; Physostigmine; Poisoning; Pyridoxine; Thioctic Acid

1984

Trials

4 trial(s) available for acetylcysteine and Heart Diseases

ArticleYear
The contrast media and nephrotoxicity following coronary revascularization by primary angioplasty for acute myocardial infarction study: design and rationale of the CONTRAST-AMI study.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2010, Volume: 11, Issue:3

    Topics: Acetylcysteine; Acute Kidney Injury; Angioplasty, Balloon, Coronary; Biomarkers; Contrast Media; Coronary Angiography; Creatinine; Heart Diseases; Humans; Iohexol; Italy; Myocardial Infarction; Prospective Studies; Research Design; Single-Blind Method; Syndrome; Time Factors; Treatment Outcome; Triiodobenzoic Acids

2010
Prevention of contrast agent-induced renal impairment in patients with chronic renal insufficiency and heart disease by high-dose intravenous N-acetylcysteine: a pilot-ministudy.
    Kardiologia polska, 2006, Volume: 64, Issue:6

    Topics: Acetylcysteine; Acute Kidney Injury; Contrast Media; Coronary Angiography; Creatinine; Heart Diseases; Humans; Infusions, Intravenous; Pilot Projects; Poland; Premedication; Renal Insufficiency, Chronic; Safety; Treatment Outcome

2006
N-acetylcysteine for prevention of acute renal failure in patients with chronic renal insufficiency undergoing cardiac surgery: a prospective, randomized, clinical trial.
    Critical care medicine, 2008, Volume: 36, Issue:1

    Topics: Acetylcysteine; Acute Kidney Injury; Aged; Creatinine; Female; Free Radical Scavengers; Heart Diseases; Humans; Length of Stay; Male; Prospective Studies; Renal Insufficiency, Chronic; Renal Replacement Therapy; Treatment Outcome

2008
[The effect of prophylactically administered n-acetylcysteine on clinical indicators for tissue oxygenation during hyperoxic ventilation in cardiac risk patients].
    Der Anaesthesist, 1996, Volume: 45, Issue:4

    Topics: Acetylcysteine; Cardiac Output; Female; Free Radical Scavengers; Heart Diseases; Hemodynamics; Humans; Hyperoxia; Male; Middle Aged; Oxygen Consumption; Prospective Studies; Respiration, Artificial; Risk Factors

1996

Other Studies

20 other study(ies) available for acetylcysteine and Heart Diseases

ArticleYear
Role of oxidative stress in clofazimine-induced cardiac dysfunction in a zebrafish model.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 132

    Topics: Acetylcysteine; Animals; Antitubercular Agents; Clofazimine; Disease Models, Animal; Gene Expression Profiling; Heart Diseases; Oxidative Stress; Zebrafish

2020
Endogenous asymmetric dimethylarginine accumulation precipitates the cardiac and mitochondrial dysfunctions in type 1 diabetic rats.
    European journal of pharmacology, 2021, Jul-05, Volume: 902

    Topics: Acetylcysteine; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Free Radical Scavengers; Glycosylation; Heart Diseases; Insulin Resistance; Male; Mitochondria; Myocardial Contraction; Myocytes, Cardiac; Nitric Oxide; Papillary Muscles; Rats, Sprague-Dawley; Signal Transduction; Streptozocin

2021
Glutaredoxin-2 controls cardiac mitochondrial dynamics and energetics in mice, and protects against human cardiac pathologies.
    Redox biology, 2018, Volume: 14

    Topics: Acetylcysteine; Animals; Cardiomegaly; Cells, Cultured; Energy Metabolism; Glutaredoxins; Heart Diseases; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Mitochondrial Dynamics; Oxidation-Reduction; Oxidative Stress; Protective Factors

2018
Cytoplasmic translocation of HuR contributes to angiotensin II induced cardiac fibrosis.
    Biochemical and biophysical research communications, 2015, Aug-07, Volume: 463, Issue:4

    Topics: Acetylcysteine; Angiotensin II; Animals; Collagen; Cytoplasm; Dose-Response Relationship, Drug; ELAV Proteins; Heart Diseases; Male; Mice; Mice, Inbred C57BL; Protein Transport; Reactive Oxygen Species; Transforming Growth Factor beta

2015
Protective effect of N-acetylcysteine on cyclophosphamide-induced cardiotoxicity in rats.
    Environmental toxicology and pharmacology, 2015, Volume: 40, Issue:2

    Topics: Acetylcysteine; Animals; Cardiotoxicity; Cyclophosphamide; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Heart Diseases; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar

2015
Hydrogen sulfide attenuates doxorubicin-induced cardiotoxicity by inhibiting reactive oxygen species-activated extracellular signal-regulated kinase 1/2 in H9c2 cardiac myocytes.
    Molecular medicine reports, 2015, Volume: 12, Issue:5

    Topics: Acetylcysteine; Animals; Antibiotics, Antineoplastic; Cardiotonic Agents; Cell Line; Cystathionine gamma-Lyase; Doxorubicin; Drug Evaluation, Preclinical; Enzyme Activation; Free Radical Scavengers; Heart Diseases; Hydrogen Sulfide; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocytes, Cardiac; Oxidative Stress; Phosphorylation; Protein Processing, Post-Translational; Rats; Reactive Oxygen Species

2015
Analysis of redox and apoptotic effects of anthracyclines to delineate a cardioprotective strategy.
    Cancer chemotherapy and pharmacology, 2015, Volume: 76, Issue:6

    Topics: Acetylcysteine; Acute Disease; Adolescent; Animals; Anthracyclines; Antioxidants; Apoptosis; Cardiotonic Agents; Cell Line; Cell Line, Tumor; Child, Preschool; Female; Heart Diseases; Humans; Jurkat Cells; Leukemia; Leukocytes, Mononuclear; Male; Mice, Inbred BALB C; Mice, SCID; Myocytes, Cardiac; Oxidation-Reduction; Oxidative Stress; Rats; Reactive Oxygen Species

2015
The effects of N-acetylcysteine on cisplatin-induced changes of cardiodynamic parameters within coronary autoregulation range in isolated rat hearts.
    Toxicology letters, 2016, Feb-03, Volume: 242

    Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Cardiotonic Agents; Cisplatin; Coronary Circulation; Coronary Vessels; Cytoprotection; Disease Models, Animal; Heart Diseases; Heart Rate; Homeostasis; Isolated Heart Preparation; Male; Myocytes, Cardiac; Oxidative Stress; Rats, Wistar; Ventricular Function, Left; Ventricular Pressure

2016
Alcoholism and alcohol abstinence: N-acetylcysteine to improve energy expenditure, myocardial oxidative stress, and energy metabolism in alcoholic heart disease.
    Alcohol (Fayetteville, N.Y.), 2009, Volume: 43, Issue:8

    Topics: Acetylcysteine; Alcoholism; Animals; Energy Metabolism; Heart Diseases; Male; Myocardium; Oxidative Stress; Oxygen Consumption; Rats; Rats, Wistar; Temperance

2009
ST segment elevation secondary to paracetamol overdose.
    Therapeutic advances in cardiovascular disease, 2011, Volume: 5, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Aged; Analgesics, Non-Narcotic; Antidotes; Coronary Angiography; Drug Overdose; Electrocardiography; Female; Heart Diseases; Humans

2011
Involvement of nuclear factor κB (NF-κB) signaling pathway in regulation of cardiac G protein-coupled receptor kinase 5 (GRK5) expression.
    The Journal of biological chemistry, 2012, Apr-13, Volume: 287, Issue:16

    Topics: Acetylcysteine; Animals; G-Protein-Coupled Receptor Kinase 5; Gene Expression Regulation, Enzymologic; Heart Diseases; Myocytes, Cardiac; NF-kappa B p50 Subunit; Primary Cell Culture; Promoter Regions, Genetic; Rats; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction; Tetradecanoylphorbol Acetate; Thiophenes; Transcription Factor RelA

2012
PM-induced cardiac oxidative stress and dysfunction are mediated by autonomic stimulation.
    Biochimica et biophysica acta, 2005, Oct-10, Volume: 1725, Issue:3

    Topics: Acetylcholine; Acetylcysteine; Air Pollutants; Animals; Autonomic Agents; Autonomic Nervous System; Glycopyrrolate; Heart Diseases; Heart Rate; Inhalation Exposure; Isoproterenol; Male; Muscarine; Oxidative Stress; Particle Size; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2005
Antioxidant N-acetylcysteine restores myocardial Mn-SOD activity and attenuates myocardial dysfunction in diabetic rats.
    European journal of pharmacology, 2006, Aug-21, Volume: 544, Issue:1-3

    Topics: Acetylcysteine; Animals; Antioxidants; Diabetes Mellitus, Experimental; Free Radical Scavengers; Heart Diseases; Immunoenzyme Techniques; Male; Myocardium; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase

2006
N-acetylcysteine: multiple organ saver during cardiac surgery?
    Critical care medicine, 2008, Volume: 36, Issue:1

    Topics: Acetylcysteine; Acute Kidney Injury; Free Radical Scavengers; Heart Diseases; Humans; Research Design; Treatment Outcome

2008
Comparison of zofenopril and lisinopril to study the role of the sulfhydryl-group in improvement of endothelial dysfunction with ACE-inhibitors in experimental heart failure.
    British journal of pharmacology, 2000, Volume: 130, Issue:8

    Topics: Acetylcholine; Acetylcysteine; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Blood Pressure; Body Weight; Calcimycin; Captopril; Endothelium, Vascular; Heart Diseases; In Vitro Techniques; Lisinopril; Male; Myocardial Infarction; Nitrates; Nitrites; Nitroglycerin; omega-N-Methylarginine; Rats; Rats, Wistar; Sodium Nitrite; Sulfhydryl Compounds; Vasodilation; Vasodilator Agents

2000
N-acetylcysteine.
    Alternative medicine review : a journal of clinical therapeutic, 2000, Volume: 5, Issue:5

    Topics: Acetaminophen; Acetylcysteine; Antidotes; Expectorants; Heart Diseases; Humans; Neoplasms; Respiratory Tract Diseases

2000
PZ-51 (Ebselen) in vivo protection against adriamycin-induced mouse cardiac and hepatic lipid peroxidation and toxicity.
    Biochemical pharmacology, 1992, Aug-18, Volume: 44, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Azoles; Body Weight; Chemical and Drug Induced Liver Injury; Creatine Kinase; Doxorubicin; Drug Interactions; Female; Heart Diseases; Isoindoles; Lipid Peroxidation; Liver Diseases; Mice; Mice, Inbred BALB C; Organoselenium Compounds

1992
Are oxygen radicals responsible for the acute cardiotoxicity of doxorubicin?
    Advances in experimental medicine and biology, 1990, Volume: 264

    Topics: Acetylcysteine; Animals; Doxorubicin; Electrocardiography; Female; Free Radicals; Heart Diseases; In Vitro Techniques; Myocardial Contraction; Oxygen; Oxypurinol; Rats

1990
Amelioration of chronic anthracycline cardiotoxicity by ICRF-187 and other compounds.
    Cancer treatment reviews, 1987, Volume: 14, Issue:3-4

    Topics: Acetylcysteine; Animals; Dogs; Doxorubicin; Heart Diseases; Piperazines; Razoxane; Swine; Vitamin E

1987
[Experiences on aerosol treatment of bronchopulmonary diseases with tetracycline-1-methylene-lysine combined with acetylcysteine].
    Gazzetta medica italiana, 1965, Volume: 124, Issue:8

    Topics: Acetylcysteine; Adolescent; Adult; Aged; Bronchial Diseases; Female; Heart Diseases; Humans; Lung Diseases; Lymecycline; Male; Middle Aged; Tetracycline

1965